| SC 13G/A | 2016-07-08 | BlackRock Inc. | Orexigen Therapeutics, Inc. | 4,110,947 | 2.8% | EDGAR |
| SC 13G/A | 2016-05-10 | FMR LLC | Orexigen Therapeutics, Inc. | 7,055,902 | 4.8% | EDGAR |
| SC 13D | 2016-03-24 | BAUPOST GROUP LLC/MA | Orexigen Therapeutics, Inc. | 27,268,399 | 18.1% | EDGAR |
| SC 13G/A | 2016-02-12 | BAUPOST GROUP LLC/MA | Orexigen Therapeutics, Inc. | 27,268,399 | 18.1% | EDGAR |
| SC 13G/A | 2016-02-12 | Foresite Capital Fund II, L.P. | Orexigen Therapeutics, Inc. | 2,000,000 | 1.4% | EDGAR |
| SC 13G/A | 2016-02-09 | PRICE T ROWE ASSOCIATES INC /MD/ | Orexigen Therapeutics, Inc. | 6,508,415 | 4.4% | EDGAR |
| SC 13G/A | 2016-01-27 | BlackRock Inc. | Orexigen Therapeutics, Inc. | 8,195,234 | 6.5% | EDGAR |
| SC 13G/A | 2016-01-11 | STATE STREET CORP | Orexigen Therapeutics, Inc. | - | 1.2% | EDGAR |
| SC 13G | 2015-10-09 | BAUPOST GROUP LLC/MA | Orexigen Therapeutics, Inc. | 25,821,363 | 17.2% | EDGAR |
| SC 13G/A | 2015-08-24 | FMR LLC | Orexigen Therapeutics, Inc. | 12,819,935 | 10.2% | EDGAR |
| SC 13G | 2015-08-04 | Foresite Capital Fund III, L.P. | Orexigen Therapeutics, Inc. | 1,229,287 | 1.0% | EDGAR |
| SC 13G/A | 2015-02-17 | Partner Fund Management, L.P. | Orexigen Therapeutics, Inc. | - | 2.6% | EDGAR |
| SC 13G/A | 2015-02-13 | FMR LLC | Orexigen Therapeutics, Inc. | 11,835,211 | 9.5% | EDGAR |
| SC 13G/A | 2015-02-13 | Capital Research Global Investors | Orexigen Therapeutics, Inc. | 5,924,493 | 4.8% | EDGAR |
| SC 13G | 2015-02-12 | PRICE T ROWE ASSOCIATES INC /MD/ | Orexigen Therapeutics, Inc. | 6,665,200 | 5.4% | EDGAR |
| SC 13G/A | 2015-02-11 | FIRST MANHATTAN CO | Orexigen Therapeutics, Inc. | 20,000 | 0.0% | EDGAR |
| SC 13G/A | 2015-02-11 | QVT Financial LP | Orexigen Therapeutics, Inc. | 0 | 0.0% | EDGAR |
| SC 13G/A | 2015-01-29 | BlackRock Inc. | Orexigen Therapeutics, Inc. | 8,476,873 | 6.9% | EDGAR |
| SC 13G/A | 2014-08-08 | Capital Research Global Investors | Orexigen Therapeutics, Inc. | 8,201,299 | 7.1% | EDGAR |
| SC 13G/A | 2014-03-10 | FMR LLC | Orexigen Therapeutics, Inc. | 11,019,159 | 10.7% | EDGAR |