| 2024-03-21 | Green JeremyRedmile Group, LLC | | Buy | Pre-Funded Warrants to Purchase Common Stock | 3636364.0 | 3,893,674 | $5.5 | A |
| 2024-02-01 | Valamehr Bahram | | Buy | Stock Option (Right to Buy) | 450000.0 | 450,000 | $0.0 | A |
| 2024-02-01 | Wolchko J Scott | | Buy | Stock Option (Right to Buy) | 500000.0 | 500,000 | $0.0 | A |
| 2024-02-01 | Dulac Edward J III | | Buy | Stock Option (Right to Buy) | 425000.0 | 425,000 | $0.0 | A |
| 2024-02-01 | TAHL CINDY | | Buy | Stock Option (Right to Buy) | 425000.0 | 425,000 | $0.0 | A |
| 2023-12-26 | Redmile Group, LLCGreen Jeremy | | Buy | Common Stock | 1655370.0 | 13,135,758 | $3.7 | J |
| 2023-12-26 | Redmile Group, LLCGreen Jeremy | | Buy | Common Stock | 44630.0 | 13,180,388 | $3.7 | P |
| 2023-06-06 | COUGHLIN TIMOTHY | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | Lee Michael Stewart | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | Jooss Karin | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | Xu Yuan | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | HERSHBERG ROBERT | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | Redmile Group, LLCGreen Jeremy | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | RASTETTER WILLIAM H | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | Agarwal Shefali | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | MENDLEIN JOHN | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-06-06 | EPSTEIN ROBERT S | | Buy | Stock Option (Right to Buy) | 40000.0 | 40,000 | $0.0 | A |
| 2023-04-21 | Green JeremyRedmile Group, LLC | | Buy | Common Stock | 256639.0 | 13,135,758 | $6.2 | P |
| 2023-04-20 | Green JeremyRedmile Group, LLC | | Buy | Common Stock | 20000.0 | 12,879,119 | $6.0 | P |
| 2023-04-14 | Redmile Group, LLCGreen Jeremy | | Buy | Common Stock | 5492385.0 | 12,833,419 | $5.8 | J |