| Chicago Capital, LLC | 5,791,735 | $85,543,929 | 4.00% |
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| Deep Track Capital, LP | 6,756,956 | $99,800,240 | 3.85% |
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| Intrinsic Edge Capital Management LLC | 1,133,099 | $16,735,872 | 1.89% |
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| Bain Capital Life Sciences Investors, LLC | 915,000 | $13,514,550 | 1.51% |
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| Kynam Capital Management, LP | 500,000 | $7,385,000 | 1.21% |
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| Rhenman & Partners Asset Management AB | 700,000 | $10,339,000 | 1.12% |
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| AlphaCentric Advisors LLC | 110,000 | $1,624,700 | 0.92% |
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| HighVista Strategies LLC | 133,000 | $1,964,410 | 0.91% |
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| Affinity Asset Advisors, LLC | 200,000 | $2,954,000 | 0.83% |
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| Rock Springs Capital Management LP | 1,813,758 | $26,789,206 | 0.72% |
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| TANG CAPITAL MANAGEMENT LLC | 300,000 | $4,431,000 | 0.62% |
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| OBERWEIS ASSET MANAGEMENT INC/ | 385,200 | $5,689,404 | 0.60% |
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| SummerHaven Investment Management, LLC | 52,174 | $770,610 | 0.57% |
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| GLOBEFLEX CAPITAL L P | 291,351 | $4,303,254 | 0.50% |
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| FEDERATED HERMES, INC. | 12,628,725 | $186,526,268 | 0.50% |
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| Eventide Asset Management | 1,425,000 | $21,047,250 | 0.38% |
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| MIZUHO MARKETS AMERICAS LLC | 704,857 | $10,410,738 | 0.36% |
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| BURNEY CO/ | 520,914 | $7,693,900 | 0.36% |
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| HUSSMAN STRATEGIC ADVISORS, INC. | 124,000 | $1,831,480 | 0.35% |
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| New Vernon Capital Holdings II LLC | 27,138 | $400,828 | 0.35% |
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