| 2024-04-08 | AGARWAL SUNIL | | Buy | Stock Option (Right to Buy) | 28200.0 | 28,200 | $0.0 | A |
| 2024-04-01 | Morabito Christopher | | Buy | Common Stock | 10000.0 | 10,000 | $3.9 | M |
| 2024-02-08 | Milne Jill C. | | Buy | Stock Option (Right to Buy) | 534600.0 | 534,600 | $0.0 | A |
| 2024-02-08 | Harshbarger Benjamin | | Buy | Stock Option (Right to Buy) | 175000.0 | 175,000 | $0.0 | A |
| 2024-02-08 | Matthews Andrea | | Buy | Stock Option (Right to Buy) | 175000.0 | 175,000 | $0.0 | A |
| 2024-02-08 | Morabito Christopher | | Buy | Stock Option (Right to Buy) | 175000.0 | 175,000 | $0.0 | A |
| 2024-02-08 | Clauser Noah | | Buy | Stock Option (Right to Buy) | 175000.0 | 175,000 | $0.0 | A |
| 2024-02-08 | Komjathy Andrew | | Buy | Stock Option (Right to Buy) | 175000.0 | 175,000 | $0.0 | A |
| 2024-02-01 | PERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTDPerceptive Xontogeny Venture Fund, LPEDELMAN JOSEPH | | Buy | Common Stock | 2481350.0 | 4,873,721 | $12.1 | P |
| 2024-01-29 | Morabito Christopher | | Buy | Common Stock | 9200.0 | 9,200 | $3.9 | M |
| 2024-01-26 | Morabito Christopher | | Buy | Common Stock | 800.0 | 800 | $3.9 | M |
| 2023-12-21 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTDPerceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLC | | Buy | Common Stock | 740000.0 | 2,392,371 | $6.2 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Common Warrants (right to buy) | 460546.0 | 345,409 | $6.5 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Common Stock | 614062.0 | 1,652,371 | $6.5 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Common Stock | 460546.0 | 1,611,699 | $6.5 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Common Warrants (right to buy) | 921093.0 | 1,151,366 | $6.5 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Pre-funded Warrants (right to buy) | 921093.0 | 921,093 | $6.5 | P |
| 2023-10-16 | Perceptive Xontogeny Venture Fund, LPEDELMAN JOSEPHPERCEPTIVE ADVISORS LLCPERCEPTIVE LIFE SCIENCES MASTER FUND LTD | | Buy | Common Warrants (right to buy) | 614062.0 | 460,546 | $6.5 | P |
| 2023-06-02 | Beck Joanne T. | | Buy | Stock Option (Right to Buy) | 14100.0 | 14,100 | $0.0 | A |
| 2023-06-02 | Clauser Noah | | Buy | Stock Option (Right to Buy) | 100000.0 | 100,000 | $0.0 | A |