| 2024-09-16 | Caligan Partners LPJOHNSON DAVID EDWARD | | Sell | Common Stock, par value $0.01 per share ("Common Stock") | -16835154.0 | 0 | $0.0 | J |
| 2024-09-16 | Caligan Partners LPJOHNSON DAVID EDWARD | | Sell | Notional Derivative Agreements (obligation to buy) | -1.0 | 0 | $0.0 | J |
| 2024-09-16 | DeMont Ross D | | Sell | Stock Option (Right to Buy) | -50000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Performance-Based Restricted Stock Units | -75000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -147000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -45000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -30000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -20000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -200000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -150000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -150000.0 | 0 | $0.0 | D |
| 2024-09-16 | Ashman Philip | | Sell | Employee Stock Option (Right to Buy) | -125000.0 | 0 | $0.0 | D |