Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Sell | Disc Medicine, Inc. | $128,975,838 | -16.1% | 2,745,335 | -20.7% | 19.98% | +4.4% | |
| AKRO | Sell | Akero Therapeutics, Inc. | $18,170,915 | -34.5% | 359,251 | -39.5% | 2.81% | -18.5% |
| New | Dianthus Therapeutics, Inc. | $3,239,503 | – | 236,979 | – | 0.50% | – | |
| MGTA | Exit | Magenta Therapeutics, Inc. | $0 | – | -3,791,698 | – | -0.36% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | Disc Medicine, Inc. | $153,703,210 | – | 3,461,784 | – | 19.13% | – | |
| KYMR | New | Kymera Therapeutics, Inc. | $134,681,443 | – | 5,858,262 | – | 16.76% | – |
| DYN | New | Dyne Therapeutics, Inc. | $111,211,301 | – | 9,885,449 | – | 13.84% | – |
| DAWN | New | Day One Biopharmaceuticals, Inc. | $90,844,224 | – | 7,608,394 | – | 11.30% | – |
| New | Vigil Neuroscience, Inc. | $54,866,616 | – | 5,836,874 | – | 6.83% | – | |
| New | Third Harmonic Bio, Inc. | $52,466,802 | – | 10,907,859 | – | 6.53% | – | |
| REPL | New | Replimune Group, Inc. | $48,722,526 | – | 2,098,300 | – | 6.06% | – |
| GBIO | New | Generation Bio, Co. | $45,537,162 | – | 8,279,484 | – | 5.67% | – |
| AVTE | New | Aerovate Therapeutics, Inc. | $34,973,120 | – | 2,039,249 | – | 4.35% | – |
| IKNA | New | Ikena Oncology, Inc. | $32,919,248 | – | 5,018,178 | – | 4.10% | – |
| AKRO | New | Akero Therapeutics, Inc. | $27,745,579 | – | 594,251 | – | 3.45% | – |
| New | Xilio Therapeutics, Inc. | $7,229,481 | – | 2,759,344 | – | 0.90% | – | |
| AVRO | New | AvroBio, Inc. | $4,314,766 | – | 4,541,381 | – | 0.54% | – |
| MGTA | New | Magenta Therapeutics, Inc. | $2,874,107 | – | 3,791,698 | – | 0.36% | – |
| SPRO | New | Spero Therapeutics, Inc. | $1,469,485 | – | 1,013,438 | – | 0.18% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| VRDN | Exit | Viridian Therapeutics, Inc. | $0 | – | -90,072 | – | -0.20% | – |
| SPRO | Exit | Spero Therapeutics, Inc. | $0 | – | -1,031,160 | – | -0.23% | – |
| AVRO | Exit | AvroBio, Inc. | $0 | – | -4,520,863 | – | -0.32% | – |
| FSTX | Exit | F-star Therapeutics, Inc. | $0 | – | -599,524 | – | -0.34% | – |
| MGTA | Exit | Magenta Therapeutics, Inc. | $0 | – | -3,476,536 | – | -0.54% | – |
| Exit | Xilio Therapeutics, Inc. | $0 | – | -2,759,344 | – | -0.89% | – | |
| GMTX | Exit | Gemini Therapeutics, Inc. | $0 | – | -5,254,365 | – | -0.95% | – |
| IKNA | Exit | Ikena Oncology, Inc. | $0 | – | -5,018,178 | – | -1.97% | – |
| AKRO | Exit | Akero Therapeutics, Inc. | $0 | – | -994,251 | – | -3.74% | – |
| AVTE | Exit | Aerovate Therapeutics, Inc. | $0 | – | -2,327,909 | – | -4.26% | – |
| GBIO | Exit | Generation Bio, Co. | $0 | – | -8,278,876 | – | -4.85% | – |
| Exit | Vigil Neuroscience, Inc. | $0 | – | -5,836,874 | – | -5.86% | – | |
| REPL | Exit | Replimune Group, Inc. | $0 | – | -3,108,300 | – | -5.92% | – |
| DYN | Exit | Dyne Therapeutics, Inc. | $0 | – | -8,934,902 | – | -12.52% | – |
| KYMR | Exit | Kymera Therapeutics, Inc. | $0 | – | -6,875,698 | – | -16.52% | – |
| DAWN | Exit | Day One Biopharmaceuticals, Inc. | $0 | – | -8,169,171 | – | -18.06% | – |
| Exit | Third Harmonic Bio, Inc. | $0 | – | -10,907,859 | – | -22.84% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | Third Harmonic Bio, Inc. | $206,922,000 | – | 10,907,859 | – | 22.84% | – | |
| DAWN | Sell | Day One Biopharmaceuticals, Inc. | $163,628,000 | +1.9% | 8,169,171 | -8.9% | 18.06% | -32.7% |
| REPL | Sell | Replimune Group, Inc. | $53,680,000 | -4.3% | 3,108,300 | -3.2% | 5.92% | -36.8% |
| AVTE | Sell | Aerovate Therapeutics, Inc. | $38,597,000 | -6.4% | 2,327,909 | -11.8% | 4.26% | -38.2% |
| AKRO | Sell | Akero Therapeutics, Inc. | $33,854,000 | +60.5% | 994,251 | -55.5% | 3.74% | +5.9% |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| DAWN | New | Day One Biopharmaceuticals, Inc. | $160,533,000 | – | 8,968,305 | – | 26.84% | – |
| KYMR | New | Kymera Therapeutics, Inc. | $135,382,000 | – | 6,875,698 | – | 22.63% | – |
| DYN | New | Dyne Therapeutics, Inc. | $61,383,000 | – | 8,934,902 | – | 10.26% | – |
| REPL | New | Replimune Group, Inc. | $56,104,000 | – | 3,209,627 | – | 9.38% | – |
| GBIO | New | Generation Bio, Co. | $54,309,000 | – | 8,278,876 | – | 9.08% | – |
| AVTE | New | Aerovate Therapeutics, Inc. | $41,237,000 | – | 2,638,297 | – | 6.89% | – |
| IKNA | New | Ikena Oncology, Inc. | $22,231,000 | – | 5,018,178 | – | 3.72% | – |
| AKRO | New | Akero Therapeutics, Inc. | $21,095,000 | – | 2,232,251 | – | 3.53% | – |
| New | Vigil Neuroscience, Inc. | $15,059,000 | – | 5,836,874 | – | 2.52% | – | |
| GMTX | New | Gemini Therapeutics, Inc. | $8,880,000 | – | 5,254,365 | – | 1.48% | – |
| New | Xilio Therapeutics, Inc. | $8,057,000 | – | 2,759,344 | – | 1.35% | – | |
| MGTA | New | Magenta Therapeutics, Inc. | $4,172,000 | – | 3,476,536 | – | 0.70% | – |
| AVRO | New | AvroBio, Inc. | $4,159,000 | – | 4,520,863 | – | 0.70% | – |
| FSTX | New | F-star Therapeutics, Inc. | $3,753,000 | – | 599,524 | – | 0.63% | – |
| VRDN | New | Viridian Therapeutics, Inc. | $1,042,000 | – | 90,072 | – | 0.17% | – |
| SPRO | New | Spero Therapeutics, Inc. | $764,000 | – | 1,031,160 | – | 0.13% | – |