$1.3 Billion is the total value of Frazier Life Sciences Management, L.P.'s 43 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 29.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Buy | HILLEVAX INC | $166,770,000 | +64.3% | 9,758,359 | +5.1% | 12.84% | +34.1% | |
| ARQT | Buy | ARCUTIS BIOTHERAPEUTICS INC | $165,956,000 | -7.7% | 8,684,232 | +3.0% | 12.78% | -24.7% |
| PHAT | Buy | PHATHOM PHARMACEUTICALS INC | $93,151,000 | +89.4% | 8,407,152 | +44.3% | 7.17% | +54.6% |
| KDNY | Buy | CHINOOK THERAPEUTICS INC | $83,861,000 | +33.4% | 4,265,559 | +18.7% | 6.46% | +8.8% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $82,010,000 | +33.4% | 3,412,838 | +6.8% | 6.32% | +8.8% |
| MIRM | Buy | MIRUM PHARMACEUTICALS INC | $80,422,000 | +15.9% | 3,827,781 | +7.3% | 6.19% | -5.5% |
| KRYS | Sell | KRYSTAL BIOTECH INC | $70,982,000 | -1.3% | 1,018,388 | -7.0% | 5.47% | -19.5% |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $46,403,000 | – | 1,894,000 | +100.0% | 3.57% | – |
| IMAGO BIOSCIENCES INC | $44,718,000 | +12.4% | 2,971,274 | 0.0% | 3.44% | -8.3% | ||
| PCVX | Sell | VAXCYTE INC | $37,138,000 | -4.5% | 1,547,405 | -13.4% | 2.86% | -22.1% |
| COGT | Sell | COGENT BIOSCIENCES INC | $30,946,000 | +63.8% | 2,074,154 | -1.0% | 2.38% | +33.7% |
| TARS | TARSUS PHARMACEUTICALS INC | $30,602,000 | +17.3% | 1,787,527 | 0.0% | 2.36% | -4.3% | |
| ALLK | New | ALLAKOS INC | $29,327,000 | – | 4,792,000 | +100.0% | 2.26% | – |
| CRNX | CRINETICS PHARMACEUTICALS IN | $27,787,000 | +5.3% | 1,414,823 | 0.0% | 2.14% | -14.1% | |
| TCDA | Buy | TRICIDA INC | $26,721,000 | +32.6% | 2,549,671 | +22.5% | 2.06% | +8.2% |
| ANAB | ANAPTYSBIO INC | $22,951,000 | +25.7% | 899,700 | 0.0% | 1.77% | +2.5% | |
| KALV | KALVISTA PHARMACEUTICALS INC | $22,813,000 | +47.5% | 1,572,192 | 0.0% | 1.76% | +20.3% | |
| ALPN | ALPINE IMMUNE SCIENCES INC | $21,497,000 | -15.4% | 2,985,757 | 0.0% | 1.66% | -31.0% | |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $21,457,000 | – | 2,099,541 | +100.0% | 1.65% | – |
| FLACU | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $15,235,000 | +2.8% | 1,501,000 | 0.0% | 1.17% | -16.1% | |
| MRUS | Buy | MERUS N V | $14,952,000 | -2.0% | 746,479 | +10.8% | 1.15% | -20.1% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $14,026,000 | – | 857,338 | +100.0% | 1.08% | – |
| REPL | REPLIMUNE GROUP INC | $13,924,000 | -1.2% | 806,267 | 0.0% | 1.07% | -19.4% | |
| GRTS | GRITSTONE BIO INC | $13,460,000 | +6.2% | 5,237,348 | 0.0% | 1.04% | -13.4% | |
| ARVN | ARVINAS INC | $12,694,000 | +5.7% | 285,331 | 0.0% | 0.98% | -13.8% | |
| Sell | TYRA BIOSCIENCES INC | $11,670,000 | +18.7% | 1,327,665 | -3.4% | 0.90% | -3.1% | |
| NTLA | INTELLIA THERAPEUTICS INC | $11,398,000 | +8.1% | 203,684 | 0.0% | 0.88% | -11.8% | |
| CERE | Buy | CEREVEL THERAPEUTICS HLDNG I | $11,106,000 | +107.7% | 393,000 | +94.3% | 0.86% | +69.3% |
| STRO | SUTRO BIOPHARMA INC | $9,859,000 | +6.5% | 1,776,479 | 0.0% | 0.76% | -13.1% | |
| GRCL | Sell | GRACELL BIOTECHNOLOGIES INCsponsored ads | $9,306,000 | -45.6% | 2,890,102 | -7.1% | 0.72% | -55.6% |
| BLUE | New | BLUEBIRD BIO INC | $9,120,000 | – | 1,440,757 | +100.0% | 0.70% | – |
| SLN | SILENCE THERAPEUTICS PLCads | $8,697,000 | -16.7% | 881,173 | 0.0% | 0.67% | -32.0% | |
| TRVI | Buy | TREVI THERAPEUTICS INC | $8,322,000 | +152.8% | 5,403,590 | +361.2% | 0.64% | +106.1% |
| AUTL | AUTOLUS THERAPEUTICS PLCspon ads | $8,018,000 | -24.4% | 3,746,857 | 0.0% | 0.62% | -38.4% | |
| ACRS | ACLARIS THERAPEUTICS INC | $6,427,000 | +12.8% | 408,329 | 0.0% | 0.50% | -8.0% | |
| PASG | Sell | PASSAGE BIO INC | $4,696,000 | -60.3% | 3,756,915 | -25.0% | 0.36% | -67.6% |
| IMVT | IMMUNOVANT INC | $3,269,000 | +43.1% | 585,759 | 0.0% | 0.25% | +16.7% | |
| MGNX | New | MACROGENICS INC | $2,428,000 | – | 701,631 | +100.0% | 0.19% | – |
| PARDES BIOSCIENCES INC | $1,564,000 | -39.8% | 845,636 | 0.0% | 0.12% | -51.0% | ||
| EPIX | ESSA PHARMA INC | $1,261,000 | -42.2% | 692,910 | 0.0% | 0.10% | -52.9% | |
| MTEM | MOLECULAR TEMPLATES INC | $1,030,000 | -17.8% | 1,374,047 | 0.0% | 0.08% | -33.1% | |
| APTX | APTINYX INC | $693,000 | -34.1% | 1,883,244 | 0.0% | 0.05% | -46.5% | |
| New | NABRIVA THERAPEUTICS PLC | $35,000 | – | 17,025 | +100.0% | 0.00% | – | |
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -425,650 | -100.0% | -0.01% | – | |
| EPZM | Exit | EPIZYME INC | $0 | – | -739,369 | -100.0% | -0.10% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -170,000 | -100.0% | -0.15% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -980,302 | -100.0% | -1.07% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -870,636 | -100.0% | -4.52% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-11-14
Signatures
The EDGAR filing(s) were signed by:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ARCUTIS BIOTHERAPEUTICS INC | 7 | Q3 2023 | 17.0% |
| MIRUM PHARMACEUTICALS INC | 7 | Q3 2023 | 13.6% |
| PHATHOM PHARMACEUTICALS INC | 7 | Q3 2023 | 8.6% |
| KRYSTAL BIOTECH INC | 7 | Q3 2023 | 7.6% |
| SYNDAX PHARMACEUTICALS INC | 7 | Q3 2023 | 6.3% |
| VAXCYTE INC | 7 | Q3 2023 | 4.8% |
| CRINETICS PHARMACEUTICALS IN | 7 | Q3 2023 | 3.1% |
| ALPINE IMMUNE SCIENCES INC | 7 | Q3 2023 | 3.2% |
| TARSUS PHARMACEUTICALS INC | 7 | Q3 2023 | 2.5% |
| KALVISTA PHARMACEUTICALS INC | 7 | Q3 2023 | 2.1% |
View Frazier Life Sciences Management, L.P.'s complete holdings history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| 13F-HR/A | 2023-02-07 |
| 13F-HR | 2023-02-03 |
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-10 |
| 13F-HR | 2022-05-16 |
View Frazier Life Sciences Management, L.P.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.