Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRUS | Buy | MERUS N V | $104,413,938 | -0.9% | 4,428,072 | +10.7% | 12.20% | +3.1% |
| PCVX | Buy | VAXCYTE INC | $56,078,000 | +10.6% | 1,100,000 | +8.4% | 6.56% | +15.1% |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $47,569,375 | – | 2,075,000 | – | 5.56% | – |
| AMAM | Buy | AMBRX BIOPHARMA INCsponsored ads | $40,463,394 | -22.6% | 3,518,556 | +10.8% | 4.73% | -19.5% |
| Buy | ENLIVEN THERAPEUTICS INC | $39,638,807 | -17.3% | 2,901,816 | +23.6% | 4.63% | -14.0% | |
| CABA | Buy | CABALETTA BIO INC | $38,441,961 | +25.7% | 2,525,753 | +6.7% | 4.49% | +30.8% |
| IMVT | Buy | IMMUNOVANT INC | $38,390,000 | +124.9% | 1,000,000 | +11.1% | 4.49% | +133.8% |
| Sell | NUVALENT INC | $38,098,925 | -21.4% | 828,778 | -27.9% | 4.45% | -18.3% | |
| AKRO | Sell | AKERO THERAPEUTICS INC | $28,577,700 | -63.5% | 565,000 | -66.3% | 3.34% | -62.0% |
| New | SOLENO THERAPEUTICS INC | $26,190,125 | – | 887,500 | – | 3.06% | – | |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $19,447,421 | -9.3% | 706,665 | +11.9% | 2.27% | -5.6% |
| CELC | Buy | CELCUITY INC | $15,484,449 | -2.3% | 1,694,141 | +17.3% | 1.81% | +1.6% |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $14,870,000 | – | 500,000 | – | 1.74% | – |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $13,903,031 | -33.4% | 957,509 | -4.0% | 1.62% | -30.7% |
| Buy | THIRD HARMONIC BIO INC | $10,863,000 | +127.4% | 1,700,000 | +71.1% | 1.27% | +136.5% | |
| New | VISTAGEN THERAPEUTICS INC | $8,253,000 | – | 1,575,000 | – | 0.96% | – | |
| New | RAYZEBIO INC | $6,413,824 | – | 288,911 | – | 0.75% | – | |
| New | APOGEE THERAPEUTICS INC | $5,325,000 | – | 250,000 | – | 0.62% | – | |
| MRSN | New | MERSANA THERAPEUTICS INC | $2,850,360 | – | 2,244,378 | – | 0.33% | – |
| New | AEGLEA BIOTHERAPEUTICS INC | $1,424,969 | – | 116,324 | – | 0.17% | – | |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -2,908,100 | – | -0.15% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -312,553 | – | -0.32% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -610,000 | – | -2.44% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -2,025,000 | – | -2.49% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRUS | New | MERUS N V | $105,320,000 | – | 4,000,000 | – | 11.84% | – |
| VERA | New | VERA THERAPEUTICS INCcl a | $87,472,500 | – | 5,450,000 | – | 9.83% | – |
| AKRO | New | AKERO THERAPEUTICS INC | $78,205,750 | – | 1,675,000 | – | 8.79% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $71,032,500 | – | 1,845,000 | – | 7.98% | – |
| COGT | New | COGENT BIOSCIENCES INC | $65,901,748 | – | 5,566,026 | – | 7.41% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $52,338,000 | – | 2,200,000 | – | 5.88% | – |
| AMAM | New | AMBRX BIOPHARMA INCsponsored ads | $52,260,500 | – | 3,175,000 | – | 5.87% | – |
| PCVX | New | VAXCYTE INC | $50,689,100 | – | 1,015,000 | – | 5.70% | – |
| New | NUVALENT INC | $48,495,500 | – | 1,150,000 | – | 5.45% | – | |
| New | ENLIVEN THERAPEUTICS INC | $47,928,232 | – | 2,348,272 | – | 5.39% | – | |
| CABA | New | CABALETTA BIO INC | $30,573,281 | – | 2,368,186 | – | 3.44% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $22,173,750 | – | 2,025,000 | – | 2.49% | – |
| ARWR | New | ARROWHEAD PHARMACEUTICALS IN | $21,752,600 | – | 610,000 | – | 2.44% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $21,432,393 | – | 631,665 | – | 2.41% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $20,879,684 | – | 997,596 | – | 2.35% | – |
| IDYA | New | IDEAYA BIOSCIENCES INC | $18,212,500 | – | 775,000 | – | 2.05% | – |
| IMVT | New | IMMUNOVANT INC | $17,073,000 | – | 900,000 | – | 1.92% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $15,900,000 | – | 10,000,000 | – | 1.79% | – |
| CELC | New | CELCUITY INC | $15,856,668 | – | 1,444,141 | – | 1.78% | – |
| KURA | New | KURA ONCOLOGY INC | $14,812,000 | – | 1,400,000 | – | 1.66% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $13,621,000 | – | 1,325,000 | – | 1.53% | – |
| DAWN | New | DAY ONE BIOPHARMACEUTICALS I | $8,831,552 | – | 739,661 | – | 0.99% | – |
| New | THIRD HARMONIC BIO INC | $4,777,744 | – | 993,294 | – | 0.54% | – | |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $2,812,977 | – | 312,553 | – | 0.32% | – |
| AGLE | New | AEGLEA BIOTHERAPEUTICS INC | $1,310,099 | – | 2,908,100 | – | 0.15% | – |
| DBVT | New | DBV TECHNOLOGIES S Asponsored adr | $176,105 | – | 92,687 | – | 0.02% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TERN | Exit | TERNS PHARMACEUTICALS INC | $0 | – | -205,870 | – | -0.20% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -750,000 | – | -0.39% | – |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -250,000 | – | -0.40% | – |
| IMUX | Exit | IMMUNIC INC | $0 | – | -893,013 | – | -0.45% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC NE | $0 | – | -467,468 | – | -0.50% | – |
| RZLT | Exit | REZOLUTE INC | $0 | – | -1,210,000 | – | -0.53% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -312,553 | – | -0.73% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -103,494 | – | -0.86% | – |
| CELC | Exit | CELCUITY INC | $0 | – | -920,464 | – | -1.49% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -1,325,000 | – | -1.53% | – |
| ALLK | Exit | ALLAKOS INC | $0 | – | -1,643,500 | – | -1.62% | – |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -1,935,609 | – | -1.70% | – |
| ABOS | Exit | ACUMEN PHARMACEUTICALS INC | $0 | – | -1,100,000 | – | -1.77% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -899,407 | – | -1.98% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -404,078 | – | -2.15% | – |
| DAWN | Exit | DAY ONE BIOPHARMACEUTICALS I | $0 | – | -739,661 | – | -2.38% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -538,812 | – | -2.44% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -738,110 | – | -2.85% | – |
| Exit | THIRD HARMONIC BIO INC | $0 | – | -1,018,569 | – | -3.11% | – | |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -5,738,500 | – | -3.23% | – |
| TCDA | Exit | TRICIDA INC | $0 | – | -1,975,403 | – | -3.33% | – |
| STSA | Exit | SATSUMA PHARMACEUTICALS INC | $0 | – | -3,711,286 | – | -3.58% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -743,472 | – | -4.07% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -2,410,622 | – | -6.10% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -893,646 | – | -6.96% | – |
| MRUS | Exit | MERUS N V | $0 | – | -2,615,762 | – | -8.42% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -5,128,557 | – | -8.71% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -2,696,340 | – | -8.89% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -1,594,932 | – | -9.26% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -4,319,940 | – | -10.36% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| COGT | Sell | COGENT BIOSCIENCES INC | $64,454,000 | +44.5% | 4,319,940 | -12.6% | 10.36% | +9.9% |
| VRDN | Buy | VIRIDIAN THERAPEUTICS INC | $55,302,000 | +191.7% | 2,696,340 | +64.6% | 8.89% | +121.9% |
| BLU | Buy | BELLUS HEALTH INC NEW | $54,158,000 | +30.8% | 5,128,557 | +14.5% | 8.71% | -0.5% |
| AKRO | New | AKERO THERAPEUTICS INC | $25,315,000 | – | 743,472 | – | 4.07% | – |
| TCDA | Sell | TRICIDA INC | $20,702,000 | +5.4% | 1,975,403 | -2.6% | 3.33% | -19.8% |
| New | THIRD HARMONIC BIO INC | $19,322,000 | – | 1,018,569 | – | 3.11% | – | |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $17,737,000 | – | 738,110 | – | 2.85% | – |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS IN | $13,355,000 | +21.4% | 404,078 | +29.3% | 2.15% | -7.7% |
| KURA | Sell | KURA ONCOLOGY INC | $12,286,000 | -63.3% | 899,407 | -50.8% | 1.98% | -72.1% |
| ABOS | New | ACUMEN PHARMACEUTICALS INC | $11,033,000 | – | 1,100,000 | – | 1.77% | – |
| ALLK | New | ALLAKOS INC | $10,058,000 | – | 1,643,500 | – | 1.62% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $9,540,000 | – | 1,325,000 | – | 1.53% | – |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $5,368,000 | – | 103,494 | – | 0.86% | – |
| ESPR | New | ESPERION THERAPEUTICS INC NE | $3,132,000 | – | 467,468 | – | 0.50% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $2,400,000 | – | 750,000 | – | 0.39% | – |
| TERN | New | TERNS PHARMACEUTICALS INC | $1,213,000 | – | 205,870 | – | 0.20% | – |
| IVA | Exit | INVENTIVA SAads | $0 | – | -175,500 | – | -0.21% | – |
| Exit | TENAYA THERAPEUTICS INC | $0 | – | -357,699 | – | -0.43% | – | |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -13,049,079 | – | -2.43% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -2,409,961 | – | -4.90% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MRUS | New | MERUS N V | $59,221,000 | – | 2,615,762 | – | 12.52% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $48,518,000 | – | 1,594,932 | – | 10.26% | – |
| COGT | New | COGENT BIOSCIENCES INC | $44,601,000 | – | 4,944,708 | – | 9.43% | – |
| BLU | New | BELLUS HEALTH INC NEW | $41,393,000 | – | 4,479,784 | – | 8.75% | – |
| CYTK | New | CYTOKINETICS INC | $35,111,000 | – | 893,646 | – | 7.42% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $33,652,000 | – | 2,410,622 | – | 7.12% | – |
| KURA | New | KURA ONCOLOGY INC | $33,480,000 | – | 1,826,491 | – | 7.08% | – |
| ISEE | New | IVERIC BIO INC | $23,184,000 | – | 2,409,961 | – | 4.90% | – |
| TCDA | New | TRICIDA INC | $19,635,000 | – | 2,028,453 | – | 4.15% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $18,959,000 | – | 1,638,609 | – | 4.01% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $16,929,000 | – | 5,738,500 | – | 3.58% | – |
| STSA | New | SATSUMA PHARMACEUTICALS INC | $15,365,000 | – | 3,711,286 | – | 3.25% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $14,526,000 | – | 538,812 | – | 3.07% | – |
| DAWN | New | DAY ONE BIOPHARMACEUTICALS I | $13,240,000 | – | 739,661 | – | 2.80% | – |
| VTGN | New | VISTAGEN THERAPEUTICS INC | $11,483,000 | – | 13,049,079 | – | 2.43% | – |
| ARWR | New | ARROWHEAD PHARMACEUTICALS IN | $11,004,000 | – | 312,533 | – | 2.33% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $8,730,000 | – | 1,935,609 | – | 1.85% | – |
| CELC | New | CELCUITY INC | $8,376,000 | – | 920,464 | – | 1.77% | – |
| RZLT | New | REZOLUTE INC | $3,908,000 | – | 1,210,000 | – | 0.83% | – |
| IMUX | New | IMMUNIC INC | $3,099,000 | – | 893,013 | – | 0.66% | – |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $3,076,000 | – | 312,553 | – | 0.65% | – |
| BLSA | New | BCLS ACQUISITION CORP | $2,475,000 | – | 250,000 | – | 0.52% | – |
| New | TENAYA THERAPEUTICS INC | $2,014,000 | – | 357,699 | – | 0.43% | – | |
| IVA | New | INVENTIVA SAads | $995,000 | – | 175,500 | – | 0.21% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -97,143 | – | -0.26% | – |
| Exit | ASTRIA THERAPEUTICS INC | $0 | – | -239,270 | – | -0.56% | – | |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -250,000 | – | -0.66% | – |
| IVA | Exit | INVENTIVA SAads | $0 | – | -262,658 | – | -0.98% | – |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -125,000 | – | -0.98% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -1,972,958 | – | -1.26% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -305,125 | – | -1.31% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -312,553 | – | -1.44% | – |
| GNCA | Exit | GENOCEA BIOSCIENCES INC | $0 | – | -3,079,756 | – | -1.56% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -226,228 | – | -1.64% | – |
| KRON | Exit | KRONOS BIO INC | $0 | – | -298,839 | – | -1.65% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -498,079 | – | -2.33% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -579,432 | – | -2.33% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -362,869 | – | -2.36% | – |
| Exit | TENAYA THERAPEUTICS INC | $0 | – | -513,930 | – | -2.80% | – | |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -667,674 | – | -2.90% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -248,207 | – | -3.53% | – |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -5,123,509 | – | -3.70% | – |
| STSA | Exit | SATSUMA PHARMACEUTICALS INC | $0 | – | -3,118,761 | – | -3.83% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -4,169,896 | – | -4.01% | – |
| MRUS | Exit | MERUS N V | $0 | – | -718,136 | – | -4.16% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -1,912,511 | – | -4.24% | – |
| CELC | Exit | CELCUITY INC | $0 | – | -920,464 | – | -4.37% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -999,433 | – | -4.94% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -481,094 | – | -5.67% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -1,292,251 | – | -6.87% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -796,578 | – | -7.51% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -2,190,291 | – | -10.39% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -2,750,137 | – | -11.78% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ISEE | Buy | IVERIC BIO INC | $44,662,000 | +304.9% | 2,750,137 | +57.3% | 11.78% | +206.4% |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $39,425,000 | +34.5% | 2,190,291 | +31.2% | 10.39% | +1.8% |
| CYTK | Buy | CYTOKINETICS INC | $28,470,000 | +104.3% | 796,578 | +13.1% | 7.51% | +54.6% |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $26,052,000 | – | 1,292,251 | – | 6.87% | – |
| KURA | Buy | KURA ONCOLOGY INC | $18,719,000 | +44.5% | 999,433 | +60.8% | 4.94% | +9.3% |
| CELC | Buy | CELCUITY INC | $16,568,000 | -20.7% | 920,464 | +5.7% | 4.37% | -40.0% |
| COGT | Buy | COGENT BIOSCIENCES INC | $16,084,000 | +45.0% | 1,912,511 | +39.8% | 4.24% | +9.8% |
| MRUS | New | MERUS N V | $15,799,000 | – | 718,136 | – | 4.16% | – |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $15,220,000 | -1.1% | 4,169,896 | +18.1% | 4.01% | -25.1% |
| STSA | Buy | SATSUMA PHARMACEUTICALS INC | $14,533,000 | -33.4% | 3,118,761 | +0.7% | 3.83% | -49.6% |
| VTGN | Buy | VISTAGEN THERAPEUTICS INC | $14,038,000 | +33.8% | 5,123,509 | +53.8% | 3.70% | +1.2% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEW | $13,401,000 | +23.9% | 248,207 | -23.3% | 3.53% | -6.2% |
| VRDN | Buy | VIRIDIAN THERAPEUTICS INC | $10,983,000 | +222.2% | 667,674 | +258.2% | 2.90% | +143.8% |
| New | TENAYA THERAPEUTICS INC | $10,613,000 | – | 513,930 | – | 2.80% | – | |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $8,948,000 | – | 362,869 | – | 2.36% | – |
| XENE | Buy | XENON PHARMACEUTICALS INC | $8,854,000 | +45.7% | 579,432 | +77.6% | 2.33% | +10.3% |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $8,826,000 | -6.6% | 498,079 | +136.5% | 2.33% | -29.3% |
| RVMD | New | REVOLUTION MEDICINES INC | $6,224,000 | – | 226,228 | – | 1.64% | – |
| GNCA | Buy | GENOCEA BIOSCIENCES INC | $5,913,000 | -13.7% | 3,079,756 | +5.1% | 1.56% | -34.7% |
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $5,454,000 | +0.4% | 312,553 | +37.9% | 1.44% | -24.0% |
| MREO | Sell | MEREO BIOPHARMA GROUP PLCads | $4,775,000 | -26.9% | 1,972,958 | -4.2% | 1.26% | -44.7% |
| New | ASTRIA THERAPEUTICS INC | $2,115,000 | – | 239,270 | – | 0.56% | – | |
| Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -1,617,000 | – | -1.19% | – | |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -145,453 | – | -1.21% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -429,228 | – | -2.03% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -281,911 | – | -2.81% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -393,850 | – | -3.69% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -440,869 | – | -5.19% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ACRS | New | ACLARIS THERAPEUTICS INC | $29,307,000 | – | 1,668,987 | – | 10.21% | – |
| STSA | New | SATSUMA PHARMACEUTICALS INC | $21,832,000 | – | 3,096,729 | – | 7.61% | – |
| CELC | New | CELCUITY INC | $20,903,000 | – | 870,967 | – | 7.28% | – |
| CCCC | New | C4 THERAPEUTICS INC | $18,205,000 | – | 481,094 | – | 6.34% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $15,388,000 | – | 3,529,465 | – | 5.36% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $14,901,000 | – | 440,869 | – | 5.19% | – |
| CYTK | New | CYTOKINETICS INC | $13,938,000 | – | 704,317 | – | 4.86% | – |
| KURA | New | KURA ONCOLOGY INC | $12,958,000 | – | 621,493 | – | 4.52% | – |
| COGT | New | COGENT BIOSCIENCES INC | $11,091,000 | – | 1,367,582 | – | 3.86% | – |
| ISEE | New | IVERIC BIO INC | $11,031,000 | – | 1,748,241 | – | 3.84% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $10,816,000 | – | 323,437 | – | 3.77% | – |
| MGNX | New | MACROGENICS INC | $10,579,000 | – | 393,850 | – | 3.69% | – |
| VTGN | New | VISTAGEN THERAPEUTICS INC | $10,494,000 | – | 3,331,315 | – | 3.66% | – |
| PTGX | New | PROTAGONIST THERAPEUTICS INC | $9,452,000 | – | 210,600 | – | 3.29% | – |
| EPIX | New | ESSA PHARMA INC | $8,054,000 | – | 281,911 | – | 2.81% | – |
| KRON | New | KRONOS BIO INC | $7,157,000 | – | 298,839 | – | 2.49% | – |
| GNCA | New | GENOCEA BIOSCIENCES INC | $6,855,000 | – | 2,929,447 | – | 2.39% | – |
| MREO | New | MEREO BIOPHARMA GROUP PLCads | $6,529,000 | – | 2,059,729 | – | 2.28% | – |
| DYN | New | DYNE THERAPEUTICS INC | $6,420,000 | – | 305,125 | – | 2.24% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $6,076,000 | – | 326,336 | – | 2.12% | – |
| MRSN | New | MERSANA THERAPEUTICS INC | $5,829,000 | – | 429,228 | – | 2.03% | – |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $5,431,000 | – | 226,671 | – | 1.89% | – |
| PMVP | New | PMV PHARMACEUTICALS INC | $4,270,000 | – | 125,000 | – | 1.49% | – |
| IVA | New | INVENTIVA SAads | $3,581,000 | – | 262,658 | – | 1.25% | – |
| MCRB | New | SERES THERAPEUTICS INC | $3,469,000 | – | 145,453 | – | 1.21% | – |
| New | CATABASIS PHARMACEUTICALS IN | $3,412,000 | – | 1,617,000 | – | 1.19% | – | |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $3,409,000 | – | 186,405 | – | 1.19% | – |
| SBTX | New | SILVERBACK THERAPEUTICS INC | $3,001,000 | – | 97,143 | – | 1.05% | – |
| BLSA | New | BCLS ACQUISITION CORP | $2,633,000 | – | 250,000 | – | 0.92% | – |