Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | New | SPDR SER TRcall | $91,275,000 | – | 1,250,000 | – | 8.42% | – |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $64,861,959 | +21.0% | 287,165 | +18.3% | 5.98% | +0.5% |
| TEVA | Buy | TEVA PHARMACEUTICAL INDS LTDsponsored ads | $61,732,073 | +92.9% | 6,052,164 | +42.4% | 5.70% | +60.1% |
| EDAP | Buy | EDAP TMS S Asponsored adr | $43,922,624 | -13.0% | 6,256,784 | +14.3% | 4.05% | -27.8% |
| SRDX | Sell | SURMODICS INC | $39,498,362 | -5.6% | 1,230,862 | -7.9% | 3.64% | -21.7% |
| ORGO | Buy | ORGANOGENESIS HLDGS INC | $39,101,798 | +0.4% | 12,296,163 | +4.8% | 3.61% | -16.7% |
| New | GSK PLCsponsored adr | $34,183,750 | – | 943,000 | – | 3.15% | – | |
| HUM | Buy | HUMANA INC | $33,473,549 | +19.3% | 68,802 | +9.6% | 3.09% | -1.0% |
| IRMD | Sell | IRADIMED CORP | $27,873,500 | -24.5% | 628,206 | -18.8% | 2.57% | -37.4% |
| PCVX | Sell | VAXCYTE INC | $25,472,157 | -10.7% | 499,650 | -12.5% | 2.35% | -25.9% |
| TMCI | New | TREACE MED CONCEPTS INC | $25,011,560 | – | 1,907,823 | – | 2.31% | – |
| TGTX | Buy | TG THERAPEUTICS INC | $24,113,434 | +122.9% | 2,884,382 | +562.3% | 2.22% | +85.0% |
| NPCE | Sell | NEUROPACE INC | $23,996,175 | +116.7% | 2,466,205 | -0.0% | 2.21% | +79.9% |
| Sell | ARCELLX INC | $23,098,719 | -27.1% | 643,777 | -35.8% | 2.13% | -39.5% | |
| Buy | TANGO THERAPEUTICS INC | $21,720,754 | +268.2% | 1,929,019 | +8.6% | 2.00% | +205.5% | |
| PODD | New | INSULET CORP | $20,363,683 | – | 127,680 | – | 1.88% | – |
| EOLS | Buy | EVOLUS INC | $18,992,920 | +156.9% | 2,078,000 | +104.3% | 1.75% | +113.1% |
| AXGN | Buy | AXOGEN INC | $18,929,145 | +15.8% | 3,785,829 | +111.5% | 1.75% | -3.9% |
| CRL | Sell | CHARLES RIV LABS INTL INC | $18,826,623 | -57.3% | 96,064 | -54.1% | 1.74% | -64.5% |
| CELC | Buy | CELCUITY INC | $18,796,264 | -11.0% | 2,056,484 | +6.9% | 1.73% | -26.1% |
| SKIN | Buy | THE BEAUTY HEALTH COMPANY | $16,896,454 | -18.7% | 2,806,720 | +13.1% | 1.56% | -32.5% |
| AXSM | Buy | AXSOME THERAPEUTICS INC | $16,598,875 | +827.7% | 237,500 | +853.8% | 1.53% | +669.3% |
| SNN | Buy | SMITH & NEPHEW PLCspdn adr new | $16,197,103 | +2.7% | 653,900 | +33.6% | 1.49% | -14.8% |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $15,987,256 | -12.6% | 14,803,015 | +4.4% | 1.48% | -27.4% |
| IMVT | Buy | IMMUNOVANT INC | $15,340,606 | +365.8% | 399,599 | +130.2% | 1.42% | +286.6% |
| KRYS | Buy | KRYSTAL BIOTECH INC | $13,675,472 | +5.7% | 117,892 | +7.0% | 1.26% | -12.2% |
| SIBN | Buy | SI-BONE INC | $13,642,218 | -19.2% | 642,289 | +2.6% | 1.26% | -33.0% |
| CVS | Sell | CVS HEALTH CORP | $13,444,120 | -45.2% | 192,554 | -45.8% | 1.24% | -54.6% |
| ATRC | New | ATRICURE INC | $13,402,800 | – | 306,000 | – | 1.24% | – |
| EPIX | Buy | ESSA PHARMA INC | $13,247,120 | +16.8% | 4,287,094 | +2.0% | 1.22% | -3.1% |
| MREO | New | MEREO BIOPHARMA GROUP PLCspon ads | $12,483,871 | – | 9,677,419 | – | 1.15% | – |
| BHC | Buy | BAUSCH HEALTH COS INC | $11,580,344 | +25.3% | 1,408,801 | +21.9% | 1.07% | +3.9% |
| Buy | VERASTEM INC | $10,954,110 | +182.9% | 1,347,369 | +158.9% | 1.01% | +135.1% | |
| BNTX | New | BIONTECH SEsponsored ads | $10,646,720 | – | 98,000 | – | 0.98% | – |
| INBX | Buy | INHIBRX INC | $10,077,508 | -18.0% | 549,183 | +16.1% | 0.93% | -31.9% |
| New | RAYZEBIO INC | $10,015,819 | – | 451,163 | – | 0.92% | – | |
| New | SOLENO THERAPEUTICS INC | $9,590,750 | – | 325,000 | – | 0.88% | – | |
| MRUS | New | MERUS N V | $9,066,274 | – | 384,490 | – | 0.84% | – |
| BCYC | Sell | BICYCLE THERAPEUTICS PLCsponsored ads | $7,871,262 | -25.1% | 391,800 | -4.9% | 0.73% | -37.8% |
| BCAB | Buy | BIOATLA INC | $7,405,535 | -42.9% | 4,356,197 | +0.8% | 0.68% | -52.6% |
| PHVS | Sell | PHARVARIS N V | $7,178,758 | +21.0% | 343,975 | -12.2% | 0.66% | +0.3% |
| CMPS | New | COMPASS PATHWAYS PLCsponsored ads | $7,137,670 | – | 964,550 | – | 0.66% | – |
| Sell | NUVALENT INC | $7,098,504 | -21.0% | 154,416 | -27.5% | 0.66% | -34.4% | |
| INSP | Buy | INSPIRE MED SYS INC | $7,064,464 | +224.8% | 35,600 | +431.3% | 0.65% | +169.4% |
| EXAS | Buy | EXACT SCIENCES CORP | $6,971,811 | +6.8% | 102,196 | +47.0% | 0.64% | -11.3% |
| NRIX | New | NURIX THERAPEUTICS INC | $6,398,040 | – | 814,000 | – | 0.59% | – |
| BLFS | New | BIOLIFE SOLUTIONS INC | $6,062,590 | – | 439,000 | – | 0.56% | – |
| Buy | JASPER THERAPEUTICS INC | $5,810,686 | -45.5% | 8,300,980 | +6.8% | 0.54% | -54.7% | |
| NVCR | Buy | NOVOCURE LTD | $5,557,215 | -45.4% | 344,100 | +40.4% | 0.51% | -54.6% |
| INSM | New | INSMED INC | $5,504,500 | – | 218,000 | – | 0.51% | – |
| ETNB | Buy | 89BIO INC | $5,342,750 | +24.5% | 346,033 | +52.8% | 0.49% | +3.4% |
| URGN | New | UROGEN PHARMA LTD | $5,211,720 | – | 372,000 | – | 0.48% | – |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $5,098,027 | +222.5% | 244,627 | +270.6% | 0.47% | +167.0% |
| New | THERATECHNOLOGIES INC | $5,012,458 | – | 2,331,376 | – | 0.46% | – | |
| CSTL | New | CASTLE BIOSCIENCES INC | $4,788,315 | – | 283,500 | – | 0.44% | – |
| TARS | New | TARSUS PHARMACEUTICALS INC | $4,442,500 | – | 250,000 | – | 0.41% | – |
| MCRB | Sell | SERES THERAPEUTICS INC | $4,333,940 | -55.8% | 1,820,983 | -11.0% | 0.40% | -63.3% |
| MIRM | Sell | MIRUM PHARMACEUTICALS INC | $3,254,800 | -28.5% | 103,000 | -41.5% | 0.30% | -40.7% |
| APLT | New | APPLIED THERAPEUTICS INC | $2,969,639 | – | 1,192,626 | – | 0.27% | – |
| New | BIOHAVEN LTD | $2,959,938 | – | 113,800 | – | 0.27% | – | |
| Buy | GENEDX HOLDINGS CORP | $2,844,281 | -32.9% | 781,396 | +9.8% | 0.26% | -44.4% | |
| KNSA | Sell | KINIKSA PHARMACEUTICALS LTD | $2,733,152 | -62.6% | 157,349 | -69.7% | 0.25% | -69.0% |
| NTRA | Sell | NATERA INC | $2,715,932 | -66.9% | 61,377 | -63.6% | 0.25% | -72.5% |
| DSGN | New | DESIGN THERAPEUTICS INC | $2,419,000 | – | 1,025,000 | – | 0.22% | – |
| PRAX | Sell | PRAXIS PRECISION MEDICINES I | $1,966,500 | -18.6% | 1,150,000 | -45.2% | 0.18% | -32.5% |
| XENE | Sell | XENON PHARMACEUTICALS INC | $1,776,320 | -30.1% | 52,000 | -21.2% | 0.16% | -41.8% |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $1,735,140 | -61.0% | 119,500 | -43.8% | 0.16% | -67.7% |
| FDMT | Sell | 4D MOLECULAR THERAPEUTICS IN | $1,575,312 | -60.2% | 123,748 | -43.5% | 0.14% | -67.0% |
| ALKS | Sell | ALKERMES PLC | $1,523,744 | -75.0% | 54,400 | -72.0% | 0.14% | -79.1% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $1,352,754 | -75.2% | 122,200 | -63.7% | 0.12% | -79.4% |
| ANNX | Sell | ANNEXON INC | $1,216,344 | -44.3% | 515,400 | -16.9% | 0.11% | -53.9% |
| KRTX | Sell | KARUNA THERAPEUTICS INC | $1,088,940 | -64.5% | 6,440 | -54.5% | 0.10% | -70.7% |
| AVDL | Sell | AVADEL PHARMACEUTICALS PLCsponsored adr | $1,071,200 | -78.8% | 104,000 | -66.1% | 0.10% | -82.4% |
| New | APOGEE THERAPEUTICS INC | $745,500 | – | 35,000 | – | 0.07% | – | |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $690,690 | – | 3,900 | – | 0.06% | – |
| GLTO | Sell | GALECTO INC | $645,864 | -74.4% | 897,657 | -10.2% | 0.06% | -78.6% |
| DCTH | New | DELCATH SYS INC | $587,080 | – | 144,958 | – | 0.05% | – |
| Sell | XERIS BIOPHARMA HOLDINGS INC | $565,594 | -89.5% | 304,083 | -85.2% | 0.05% | -91.3% | |
| SBTX | New | ARS PHARMACEUTICALS INC | $567,000 | – | 150,000 | – | 0.05% | – |
| KROS | Sell | KEROS THERAPEUTICS INC | $404,876 | -85.8% | 12,700 | -82.1% | 0.04% | -88.3% |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -25,887 | – | -0.01% | – |
| Exit | PARAGON 28 INC | $0 | – | -10,000 | – | -0.02% | – | |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -21,600 | – | -0.04% | – |
| Exit | INDIVIOR PLCord | $0 | – | -18,624 | – | -0.05% | – | |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -21,700 | – | -0.05% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -13,600 | – | -0.05% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -320,000 | – | -0.06% | – |
| LUNG | Exit | PULMONX CORP | $0 | – | -41,000 | – | -0.06% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -33,500 | – | -0.07% | – |
| RYTM | Exit | RHYTHM PHARMACEUTICALS INC | $0 | – | -38,600 | – | -0.07% | – |
| Exit | VENTYX BIOSCIENCES INC | $0 | – | -21,300 | – | -0.08% | – | |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -13,600 | – | -0.09% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -34,000 | – | -0.09% | – |
| IMCR | Exit | IMMUNOCORE HLDGS PLCads | $0 | – | -16,400 | – | -0.11% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -39,800 | – | -0.12% | – |
| Exit | MINERALYS THERAPEUTICS INC | $0 | – | -76,817 | – | -0.15% | – | |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -46,000 | – | -0.16% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -151,000 | – | -0.17% | – |
| LLY | Exit | LILLY ELI & CO | $0 | – | -4,300 | – | -0.22% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -435,000 | – | -0.24% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -42,400 | – | -0.26% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -67,049 | – | -0.28% | – |
| Exit | AMYLYX PHARMACEUTICALS INC | $0 | – | -120,000 | – | -0.29% | – | |
| TWST | Exit | TWIST BIOSCIENCE CORP | $0 | – | -160,000 | – | -0.36% | – |
| Exit | DICE THERAPEUTICS INC | $0 | – | -80,000 | – | -0.41% | – | |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -373,000 | – | -0.45% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -33,000 | – | -0.47% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -57,800 | – | -0.56% | – |
| TMDX | Exit | TRANSMEDICS GROUP INC | $0 | – | -74,200 | – | -0.69% | – |
| BBIO | Exit | BRIDGEBIO PHARMA INC | $0 | – | -364,000 | – | -0.70% | – |
| THTX | Exit | THERATECHNOLOGIES INC | $0 | – | -9,325,511 | – | -0.87% | – |
| ANGO | Exit | ANGIODYNAMICS INC | $0 | – | -768,500 | – | -0.89% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -45,900 | – | -0.96% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -97,547 | – | -1.11% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -71,000 | – | -1.52% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $53,583,751 | – | 242,735 | – | 5.96% | – |
| EDAP | New | EDAP TMS S Asponsored adr | $50,472,327 | – | 5,474,222 | – | 5.61% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $44,046,534 | – | 209,496 | – | 4.90% | – |
| SRDX | New | SURMODICS INC | $41,856,398 | – | 1,336,838 | – | 4.65% | – |
| ORGO | New | ORGANOGENESIS HLDGS INC | $38,937,169 | – | 11,728,063 | – | 4.33% | – |
| IRMD | New | IRADIMED CORP | $36,936,152 | – | 773,694 | – | 4.11% | – |
| TEVA | New | TEVA PHARMACEUTICAL INDS LTDsponsored ads | $32,002,500 | – | 4,250,000 | – | 3.56% | – |
| New | ARCELLX INC | $31,683,208 | – | 1,001,999 | – | 3.52% | – | |
| PCVX | New | VAXCYTE INC | $28,528,225 | – | 571,250 | – | 3.17% | – |
| HUM | New | HUMANA INC | $28,057,408 | – | 62,750 | – | 3.12% | – |
| CVS | New | CVS HEALTH CORP | $24,544,883 | – | 355,054 | – | 2.73% | – |
| CELC | New | CELCUITY INC | $21,117,647 | – | 1,923,283 | – | 2.35% | – |
| SKIN | New | THE BEAUTY HEALTH COMPANY | $20,772,574 | – | 2,481,789 | – | 2.31% | – |
| RIGL | New | RIGEL PHARMACEUTICALS INC | $18,289,639 | – | 14,178,015 | – | 2.03% | – |
| SIBN | New | SI-BONE INC | $16,893,365 | – | 626,144 | – | 1.88% | – |
| AXGN | New | AXOGEN INC | $16,342,682 | – | 1,789,998 | – | 1.82% | – |
| SNN | New | SMITH & NEPHEW PLCspdn adr new | $15,778,893 | – | 489,268 | – | 1.75% | – |
| SGEN | New | SEAGEN INC | $13,664,660 | – | 71,000 | – | 1.52% | – |
| BCAB | New | BIOATLA INC | $12,963,591 | – | 4,321,197 | – | 1.44% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $12,936,541 | – | 110,192 | – | 1.44% | – |
| INBX | New | INHIBRX INC | $12,283,831 | – | 473,183 | – | 1.37% | – |
| EPIX | New | ESSA PHARMA INC | $11,345,654 | – | 4,202,094 | – | 1.26% | – |
| NPCE | New | NEUROPACE INC | $11,073,301 | – | 2,466,214 | – | 1.23% | – |
| TGTX | New | TG THERAPEUTICS INC | $10,817,820 | – | 435,500 | – | 1.20% | – |
| New | JASPER THERAPEUTICS INC | $10,653,093 | – | 7,775,980 | – | 1.18% | – | |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $10,509,136 | – | 411,800 | – | 1.17% | – |
| NVCR | New | NOVOCURE LTD | $10,171,650 | – | 245,100 | – | 1.13% | – |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $9,945,892 | – | 97,547 | – | 1.11% | – |
| MCRB | New | SERES THERAPEUTICS INC | $9,800,259 | – | 2,045,983 | – | 1.09% | – |
| BHC | New | BAUSCH HEALTH COS INC | $9,244,000 | – | 1,155,500 | – | 1.03% | – |
| New | NUVALENT INC | $8,982,210 | – | 213,000 | – | 1.00% | – | |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $8,728,030 | – | 1,239,777 | – | 0.97% | – |
| ILMN | New | ILLUMINA INC | $8,605,791 | – | 45,900 | – | 0.96% | – |
| NTRA | New | NATERA INC | $8,213,808 | – | 168,800 | – | 0.91% | – |
| ANGO | New | ANGIODYNAMICS INC | $8,015,455 | – | 768,500 | – | 0.89% | – |
| THTX | New | THERATECHNOLOGIES INC | $7,845,077 | – | 9,325,511 | – | 0.87% | – |
| CCCC | New | C4 THERAPEUTICS INC | $7,403,055 | – | 2,692,020 | – | 0.82% | – |
| EOLS | New | EVOLUS INC | $7,393,590 | – | 1,017,000 | – | 0.82% | – |
| KNSA | New | KINIKSA PHARMACEUTICALS LTD | $7,316,531 | – | 519,640 | – | 0.81% | – |
| EXAS | New | EXACT SCIENCES CORP | $6,526,050 | – | 69,500 | – | 0.72% | – |
| BBIO | New | BRIDGEBIO PHARMA INC | $6,260,800 | – | 364,000 | – | 0.70% | – |
| TMDX | New | TRANSMEDICS GROUP INC | $6,231,316 | – | 74,200 | – | 0.69% | – |
| ALKS | New | ALKERMES PLC | $6,084,720 | – | 194,400 | – | 0.68% | – |
| PHVS | New | PHARVARIS N V | $5,933,366 | – | 391,900 | – | 0.66% | – |
| New | TANGO THERAPEUTICS INC | $5,899,298 | – | 1,776,897 | – | 0.66% | – | |
| VKTX | New | VIKING THERAPEUTICS INC | $5,457,907 | – | 336,700 | – | 0.61% | – |
| New | XERIS BIOPHARMA HOLDINGS INC | $5,381,755 | – | 2,054,105 | – | 0.60% | – | |
| AVDL | New | AVADEL PHARMACEUTICALS PLCsponsored adr | $5,059,360 | – | 307,000 | – | 0.56% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $5,010,104 | – | 57,800 | – | 0.56% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $4,553,120 | – | 176,000 | – | 0.51% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $4,449,718 | – | 212,600 | – | 0.50% | – |
| ETNB | New | 89BIO INC | $4,292,175 | – | 226,500 | – | 0.48% | – |
| New | GENEDX HOLDINGS CORP | $4,239,920 | – | 711,396 | – | 0.47% | – | |
| DXCM | New | DEXCOM INC | $4,240,830 | – | 33,000 | – | 0.47% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $4,084,350 | – | 373,000 | – | 0.45% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $3,960,004 | – | 219,148 | – | 0.44% | – |
| New | VERASTEM INC | $3,871,545 | – | 520,369 | – | 0.43% | – | |
| New | DICE THERAPEUTICS INC | $3,716,800 | – | 80,000 | – | 0.41% | – | |
| NSPR | New | INSPIREMD INC | $3,459,101 | – | 1,378,128 | – | 0.38% | – |
| IMVT | New | IMMUNOVANT INC | $3,293,173 | – | 173,599 | – | 0.37% | – |
| TWST | New | TWIST BIOSCIENCE CORP | $3,273,600 | – | 160,000 | – | 0.36% | – |
| KRTX | New | KARUNA THERAPEUTICS INC | $3,066,259 | – | 14,140 | – | 0.34% | – |
| KROS | New | KEROS THERAPEUTICS INC | $2,844,744 | – | 70,800 | – | 0.32% | – |
| New | AMYLYX PHARMACEUTICALS INC | $2,588,400 | – | 120,000 | – | 0.29% | – | |
| XENE | New | XENON PHARMACEUTICALS INC | $2,541,000 | – | 66,000 | – | 0.28% | – |
| GLTO | New | GALECTO INC | $2,520,000 | – | 1,000,000 | – | 0.28% | – |
| VCEL | New | VERICEL CORP | $2,519,031 | – | 67,049 | – | 0.28% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $2,434,834 | – | 592,417 | – | 0.27% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $2,415,000 | – | 2,100,000 | – | 0.27% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $2,380,336 | – | 42,400 | – | 0.26% | – |
| New | AADI BIOSCIENCE INC | $2,279,273 | – | 333,227 | – | 0.25% | – | |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $2,196,750 | – | 435,000 | – | 0.24% | – |
| ANNX | New | ANNEXON INC | $2,183,808 | – | 620,400 | – | 0.24% | – |
| INSP | New | INSPIRE MED SYS INC | $2,175,088 | – | 6,700 | – | 0.24% | – |
| LLY | New | LILLY ELI & CO | $2,016,614 | – | 4,300 | – | 0.22% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $1,789,314 | – | 24,900 | – | 0.20% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $1,580,700 | – | 66,000 | – | 0.18% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $1,565,870 | – | 151,000 | – | 0.17% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $1,462,340 | – | 46,000 | – | 0.16% | – |
| LQDA | New | LIQUIDIA CORPORATION | $1,373,750 | – | 175,000 | – | 0.15% | – |
| New | MINERALYS THERAPEUTICS INC | $1,309,730 | – | 76,817 | – | 0.15% | – | |
| RCEL | New | AVITA MEDICAL INC | $1,275,750 | – | 75,000 | – | 0.14% | – |
| PTGX | New | PROTAGONIST THERAPEUTICS INC | $1,099,276 | – | 39,800 | – | 0.12% | – |
| YMAB | New | Y-MABS THERAPEUTICS INC | $1,067,266 | – | 157,182 | – | 0.12% | – |
| IMCR | New | IMMUNOCORE HLDGS PLCads | $983,344 | – | 16,400 | – | 0.11% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $905,390 | – | 88,073 | – | 0.10% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $808,860 | – | 34,000 | – | 0.09% | – |
| MORF | New | MORPHIC HLDG INC | $779,688 | – | 13,600 | – | 0.09% | – |
| IMUX | New | IMMUNIC INC | $753,000 | – | 300,000 | – | 0.08% | – |
| New | VENTYX BIOSCIENCES INC | $698,640 | – | 21,300 | – | 0.08% | – | |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $636,514 | – | 38,600 | – | 0.07% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $607,020 | – | 33,500 | – | 0.07% | – |
| New | XILIO THERAPEUTICS INC | $594,585 | – | 226,941 | – | 0.07% | – | |
| LUNG | New | PULMONX CORP | $537,510 | – | 41,000 | – | 0.06% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $508,800 | – | 320,000 | – | 0.06% | – |
| VRNA | New | VERONA PHARMA PLCsponsored ads | $458,738 | – | 21,700 | – | 0.05% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $461,448 | – | 13,600 | – | 0.05% | – |
| New | INDIVIOR PLCord | $443,251 | – | 18,624 | – | 0.05% | – | |
| TVTX | New | TRAVERE THERAPEUTICS INC | $331,776 | – | 21,600 | – | 0.04% | – |
| New | PARAGON 28 INC | $177,400 | – | 10,000 | – | 0.02% | – | |
| STRO | New | SUTRO BIOPHARMA INC | $120,375 | – | 25,887 | – | 0.01% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -19,518 | – | -0.05% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -25,300 | – | -0.06% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -21,200 | – | -0.06% | – |
| Exit | DA32 LIFE SCNCE TEC ACQSTN C | $0 | – | -50,000 | – | -0.07% | – | |
| IMUX | Exit | IMMUNIC INC | $0 | – | -240,000 | – | -0.10% | – |
| Exit | IO BIOTECH INC | $0 | – | -288,119 | – | -0.11% | – | |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -13,400 | – | -0.12% | – |
| Exit | BRIDGEBIO PHARMA INCnote 2.500% 3/1 | $0 | – | -1,950,000 | – | -0.16% | – | |
| Exit | PEPGEN INC | $0 | – | -130,000 | – | -0.16% | – | |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -87,182 | – | -0.17% | – |
| Exit | XILIO THERAPEUTICS INC | $0 | – | -453,660 | – | -0.18% | – | |
| VSTM | Exit | VERASTEM INC | $0 | – | -1,644,500 | – | -0.19% | – |
| NVO | Exit | NOVO-NORDISK A Sadr | $0 | – | -14,100 | – | -0.19% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -22,000 | – | -0.20% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -67,300 | – | -0.20% | – |
| KDNY | Exit | CHINOOK THERAPEUTICS INC | $0 | – | -78,000 | – | -0.21% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -64,027 | – | -0.22% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -219,000 | – | -0.22% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -330,000 | – | -0.26% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -23,836 | – | -0.26% | – |
| INMD | Exit | INMODE LTD | $0 | – | -67,449 | – | -0.27% | – |
| OSUR | Exit | ORASURE TECHNOLOGIES INC | $0 | – | -565,000 | – | -0.29% | – |
| MIRM | Exit | MIRUM PHARMACEUTICALS INC | $0 | – | -135,618 | – | -0.39% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -592,417 | – | -0.40% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -234,026 | – | -0.41% | – |
| Exit | IMAGO BIOSCIENCES INC | $0 | – | -213,000 | – | -0.44% | – | |
| NVRO | Exit | NEVRO CORP | $0 | – | -72,000 | – | -0.46% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -62,620 | – | -0.46% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -96,800 | – | -0.48% | – |
| CELC | Exit | CELCUITY INC | $0 | – | -443,912 | – | -0.61% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -144,800 | – | -0.64% | – |
| Exit | ENOVIS CORPORATION | $0 | – | -102,100 | – | -0.64% | – | |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -4,134,868 | – | -0.65% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -2,640,539 | – | -0.65% | – |
| AXGN | Exit | AXOGEN INC | $0 | – | -424,998 | – | -0.69% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -5,587,789 | – | -0.72% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -27,000 | – | -0.73% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -146,000 | – | -0.75% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -23,200 | – | -0.84% | – |
| APEN | Exit | APOLLO ENDOSURGERY INC | $0 | – | -1,137,105 | – | -0.85% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -123,014 | – | -0.87% | – |
| ISRG | Exit | INTUITIVE SURGICAL INC | $0 | – | -34,800 | – | -0.89% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -363,902 | – | -0.89% | – |
| NRIX | Exit | NURIX THERAPEUTICS INC | $0 | – | -504,144 | – | -0.89% | – |
| HUM | Exit | HUMANA INC | $0 | – | -14,200 | – | -0.94% | – |
| TMDX | Exit | TRANSMEDICS GROUP INC | $0 | – | -175,300 | – | -0.99% | – |
| NARI | Exit | INARI MED INC | $0 | – | -101,608 | – | -1.00% | – |
| CSTL | Exit | CASTLE BIOSCIENCES INC | $0 | – | -297,840 | – | -1.06% | – |
| PCVX | Exit | VAXCYTE INC | $0 | – | -335,650 | – | -1.10% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -374,000 | – | -1.18% | – |
| NPCE | Exit | NEUROPACE INC | $0 | – | -2,334,003 | – | -1.19% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -1,025,200 | – | -1.33% | – |
| CVRX | Exit | CVRX INC | $0 | – | -1,059,040 | – | -1.34% | – |
| Exit | DICE THERAPEUTICS INC | $0 | – | -535,358 | – | -1.48% | – | |
| CUTR | Exit | CUTERA INC | $0 | – | -255,792 | – | -1.58% | – |
| INSP | Exit | INSPIRE MED SYS INC | $0 | – | -67,400 | – | -1.62% | – |
| NTRA | Exit | NATERA INC | $0 | – | -275,673 | – | -1.64% | – |
| Exit | AMYLYX PHARMACEUTICALS INC | $0 | – | -429,336 | – | -1.64% | – | |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -1,441,513 | – | -1.72% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -207,332 | – | -1.96% | – |
| NVST | Exit | ENVISTA HOLDINGS CORPORATION | $0 | – | -480,000 | – | -2.14% | – |
| THTX | Exit | THERATECHNOLOGIES INC | $0 | – | -8,007,714 | – | -2.58% | – |
| TNDM | Exit | TANDEM DIABETES CARE INC | $0 | – | -415,200 | – | -2.70% | – |
| IRMD | Exit | IRADIMED CORP | $0 | – | -684,690 | – | -2.80% | – |
| ORGO | Exit | ORGANOGENESIS HLDGS INC | $0 | – | -6,489,063 | – | -2.86% | – |
| Exit | ARCELLX INC | $0 | – | -1,239,913 | – | -3.16% | – | |
| SRDX | Exit | SURMODICS INC | $0 | – | -768,478 | – | -3.17% | – |
| CRL | Exit | CHARLES RIV LABS INTL INC | $0 | – | -129,100 | – | -3.45% | – |
| LLY | Exit | LILLY ELI & CO | $0 | – | -80,800 | – | -3.55% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -3,400,503 | – | -3.56% | – |
| CVS | Exit | CVS HEALTH CORP | $0 | – | -285,900 | – | -3.70% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -151,600 | – | -3.93% | – |
| SKIN | Exit | THE BEAUTY HEALTH COMPANY | $0 | – | -2,665,876 | – | -4.27% | – |
| EDAP | Exit | EDAP TMS S Asponsored adr | $0 | – | -4,889,745 | – | -5.48% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -2,502,601 | – | -6.10% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -234,859 | – | -6.68% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $49,175,000 | -29.4% | 234,859 | -20.5% | 6.68% | -38.5% |
| ISEE | Buy | IVERIC BIO INC | $44,897,000 | +410.4% | 2,502,601 | +173.7% | 6.10% | +344.6% |
| EDAP | Buy | EDAP TMS S Asponsored adr | $40,340,000 | +80.6% | 4,889,745 | +48.9% | 5.48% | +57.3% |
| SKIN | Sell | THE BEAUTY HEALTH COMPANY | $31,431,000 | -25.4% | 2,665,876 | -18.6% | 4.27% | -35.0% |
| ILMN | New | ILLUMINA INC | $28,924,000 | – | 151,600 | – | 3.93% | – |
| CVS | Buy | CVS HEALTH CORP | $27,266,000 | +34.1% | 285,900 | +30.3% | 3.70% | +16.8% |
| BCAB | Buy | BIOATLA INC | $26,184,000 | +181.6% | 3,400,503 | +4.2% | 3.56% | +145.2% |
| LLY | New | LILLY ELI & CO | $26,127,000 | – | 80,800 | – | 3.55% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $25,407,000 | – | 129,100 | – | 3.45% | – |
| SRDX | Buy | SURMODICS INC | $23,362,000 | -5.1% | 768,478 | +16.3% | 3.17% | -17.3% |
| Buy | ARCELLX INC | $23,273,000 | +41.5% | 1,239,913 | +36.3% | 3.16% | +23.2% | |
| ORGO | Buy | ORGANOGENESIS HLDGS INC | $21,025,000 | -18.5% | 6,489,063 | +22.8% | 2.86% | -29.0% |
| IRMD | Buy | IRADIMED CORP | $20,582,000 | -2.3% | 684,690 | +10.3% | 2.80% | -14.9% |
| TNDM | Buy | TANDEM DIABETES CARE INC | $19,867,000 | +82.6% | 415,200 | +125.9% | 2.70% | +59.0% |
| THTX | Buy | THERATECHNOLOGIES INC | $18,978,000 | +6.9% | 8,007,714 | +2.4% | 2.58% | -6.9% |
| NVST | New | ENVISTA HOLDINGS CORPORATION | $15,749,000 | – | 480,000 | – | 2.14% | – |
| KRYS | Sell | KRYSTAL BIOTECH INC | $14,451,000 | +2.6% | 207,332 | -3.3% | 1.96% | -10.6% |
| CCCC | Buy | C4 THERAPEUTICS INC | $12,642,000 | +493.2% | 1,441,513 | +410.0% | 1.72% | +417.5% |
| New | AMYLYX PHARMACEUTICALS INC | $12,086,000 | – | 429,336 | – | 1.64% | – | |
| NTRA | Buy | NATERA INC | $12,080,000 | +158.5% | 275,673 | +109.0% | 1.64% | +125.1% |
| INSP | Sell | INSPIRE MED SYS INC | $11,955,000 | -26.4% | 67,400 | -24.2% | 1.62% | -35.9% |
| CUTR | Sell | CUTERA INC | $11,664,000 | +20.7% | 255,792 | -0.7% | 1.58% | +5.2% |
| Sell | DICE THERAPEUTICS INC | $10,857,000 | -14.2% | 535,358 | -34.4% | 1.48% | -25.3% | |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $9,821,000 | +23.6% | 1,025,200 | +42.5% | 1.33% | +7.7% |
| VCEL | New | VERICEL CORP | $8,677,000 | – | 374,000 | – | 1.18% | – |
| PCVX | Sell | VAXCYTE INC | $8,056,000 | -0.1% | 335,650 | -9.4% | 1.10% | -13.0% |
| CSTL | New | CASTLE BIOSCIENCES INC | $7,768,000 | – | 297,840 | – | 1.06% | – |
| NARI | Buy | INARI MED INC | $7,381,000 | +50.1% | 101,608 | +40.5% | 1.00% | +30.8% |
| TMDX | Sell | TRANSMEDICS GROUP INC | $7,317,000 | +26.1% | 175,300 | -5.0% | 0.99% | +9.8% |
| HUM | New | HUMANA INC | $6,890,000 | – | 14,200 | – | 0.94% | – |
| NRIX | Sell | NURIX THERAPEUTICS INC | $6,569,000 | -47.9% | 504,144 | -49.3% | 0.89% | -54.6% |
| INBX | New | INHIBRX INC | $6,532,000 | – | 363,902 | – | 0.89% | – |
| ISRG | New | INTUITIVE SURGICAL INC | $6,523,000 | – | 34,800 | – | 0.89% | – |
| ENTA | Buy | ENANTA PHARMACEUTICALS INC | $6,381,000 | +35.0% | 123,014 | +23.0% | 0.87% | +17.6% |
| APEN | Sell | APOLLO ENDOSURGERY INC | $6,265,000 | -47.5% | 1,137,105 | -65.2% | 0.85% | -54.3% |
| BIIB | New | BIOGEN INC | $6,194,000 | – | 23,200 | – | 0.84% | – |
| KROS | New | KEROS THERAPEUTICS INC | $5,493,000 | – | 146,000 | – | 0.75% | – |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $5,404,000 | +84.3% | 27,000 | +34.3% | 0.73% | +60.6% |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $5,308,000 | – | 5,587,789 | – | 0.72% | – |
| AXGN | New | AXOGEN INC | $5,066,000 | – | 424,998 | – | 0.69% | – |
| EPIX | Sell | ESSA PHARMA INC | $4,806,000 | -63.4% | 2,640,539 | -36.7% | 0.65% | -68.1% |
| EXAS | Buy | EXACT SCIENCES CORP | $4,705,000 | +0.4% | 144,800 | +21.7% | 0.64% | -12.6% |
| New | ENOVIS CORPORATION | $4,704,000 | – | 102,100 | – | 0.64% | – | |
| CELC | Buy | CELCUITY INC | $4,457,000 | +16.9% | 443,912 | +6.0% | 0.61% | +1.8% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $3,494,000 | +53.1% | 96,800 | +29.1% | 0.48% | +33.4% |
| ESTA | Sell | ESTABLISHMENT LABS HLDGS INC | $3,420,000 | -19.8% | 62,620 | -20.1% | 0.46% | -30.1% |
| NVRO | New | NEVRO CORP | $3,355,000 | – | 72,000 | – | 0.46% | – |
| New | IMAGO BIOSCIENCES INC | $3,206,000 | – | 213,000 | – | 0.44% | – | |
| FGEN | Sell | FIBROGEN INC | $3,045,000 | -4.6% | 234,026 | -22.6% | 0.41% | -16.9% |
| MIRM | Sell | MIRUM PHARMACEUTICALS INC | $2,849,000 | -25.3% | 135,618 | -30.8% | 0.39% | -35.0% |
| OSUR | New | ORASURE TECHNOLOGIES INC | $2,141,000 | – | 565,000 | – | 0.29% | – |
| INMD | Sell | INMODE LTD | $1,963,000 | -53.3% | 67,449 | -64.0% | 0.27% | -59.2% |
| DXCM | Sell | DEXCOM INC | $1,920,000 | -45.5% | 23,836 | -49.5% | 0.26% | -52.5% |
| ETNB | New | 89BIO INC | $1,911,000 | – | 330,000 | – | 0.26% | – |
| EIGR | Sell | EIGER BIOPHARMACEUTICALS INC | $1,649,000 | -69.1% | 219,000 | -74.1% | 0.22% | -73.0% |
| ANAB | Sell | ANAPTYSBIO INC | $1,633,000 | -87.5% | 64,027 | -90.1% | 0.22% | -89.1% |
| KDNY | Sell | CHINOOK THERAPEUTICS INC | $1,533,000 | -0.4% | 78,000 | -11.4% | 0.21% | -13.3% |
| FATE | Sell | FATE THERAPEUTICS INC | $1,508,000 | -68.7% | 67,300 | -65.4% | 0.20% | -72.7% |
| NVO | New | NOVO-NORDISK A Sadr | $1,405,000 | – | 14,100 | – | 0.19% | – |
| YMAB | Sell | Y-MABS THERAPEUTICS INC | $1,257,000 | -39.0% | 87,182 | -36.0% | 0.17% | -46.7% |
| Sell | PEPGEN INC | $1,180,000 | -32.1% | 130,000 | -25.7% | 0.16% | -41.0% | |
| APLS | New | APELLIS PHARMACEUTICALS INC | $915,000 | – | 13,400 | – | 0.12% | – |
| Sell | IO BIOTECH INC | $781,000 | -74.5% | 288,119 | -56.0% | 0.11% | -77.8% | |
| PLRX | Sell | PLIANT THERAPEUTICS INC | $443,000 | -88.7% | 21,200 | -95.7% | 0.06% | -90.2% |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $404,000 | -90.8% | 25,300 | -92.0% | 0.06% | -91.9% |
| VRDN | Sell | VIRIDIAN THERAPEUTICS INC | $400,000 | -95.9% | 19,518 | -97.7% | 0.05% | -96.4% |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -825,000 | – | -0.11% | – |
| NVCR | Exit | NOVOCURE LTD | $0 | – | -13,275 | – | -0.14% | – |
| OM | Exit | OUTSET MED INC | $0 | – | -69,200 | – | -0.16% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -95,485 | – | -0.19% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -252,000 | – | -0.32% | – |
| LNTH | Exit | LANTHEUS HLDGS INC | $0 | – | -55,222 | – | -0.57% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -154,400 | – | -0.60% | – |
| STAA | Exit | STAAR SURGICAL CO | $0 | – | -75,094 | – | -0.83% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -79,700 | – | -0.94% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -77,842 | – | -0.97% | – |
| SUPN | Exit | SUPERNUS PHARMACEUTICALS INC | $0 | – | -258,100 | – | -1.16% | – |
| STE | Exit | STERIS PLC | $0 | – | -37,310 | – | -1.20% | – |
| PEN | Exit | PENUMBRA INC | $0 | – | -68,800 | – | -1.34% | – |
| EOLS | Exit | EVOLUS INC | $0 | – | -810,676 | – | -1.47% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -169,696 | – | -1.75% | – |
| ANGO | Exit | ANGIODYNAMICS INC | $0 | – | -670,000 | – | -2.02% | – |
| SKIN | Exit | THE BEAUTY HEALTH COMPANYcall | $0 | – | -1,300,000 | – | -2.61% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $69,641,000 | – | 295,541 | – | 10.86% | – |
| SKIN | New | THE BEAUTY HEALTH COMPANY | $42,130,000 | – | 3,276,037 | – | 6.57% | – |
| ORGO | New | ORGANOGENESIS HLDGS INC | $25,796,000 | – | 5,286,167 | – | 4.02% | – |
| SRDX | New | SURMODICS INC | $24,609,000 | – | 661,004 | – | 3.84% | – |
| EDAP | New | EDAP TMS S Asponsored adr | $22,332,000 | – | 3,284,189 | – | 3.48% | – |
| IRMD | New | IRADIMED CORP | $21,069,000 | – | 620,765 | – | 3.29% | – |
| CVS | New | CVS HEALTH CORP | $20,330,000 | – | 219,400 | – | 3.17% | – |
| THTX | New | THERATECHNOLOGIES INC | $17,757,000 | – | 7,822,412 | – | 2.77% | – |
| SKIN | New | THE BEAUTY HEALTH COMPANYcall | $16,718,000 | – | 1,300,000 | – | 2.61% | – |
| New | ARCELLX INC | $16,448,000 | – | 909,739 | – | 2.57% | – | |
| INSP | New | INSPIRE MED SYS INC | $16,248,000 | – | 88,950 | – | 2.54% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $14,083,000 | – | 214,482 | – | 2.20% | – |
| EPIX | New | ESSA PHARMA INC | $13,132,000 | – | 4,168,799 | – | 2.05% | – |
| ANAB | New | ANAPTYSBIO INC | $13,065,000 | – | 643,575 | – | 2.04% | – |
| ANGO | New | ANGIODYNAMICS INC | $12,965,000 | – | 670,000 | – | 2.02% | – |
| New | DICE THERAPEUTICS INC | $12,660,000 | – | 815,740 | – | 1.98% | – | |
| NRIX | New | NURIX THERAPEUTICS INC | $12,600,000 | – | 994,492 | – | 1.97% | – |
| APEN | New | APOLLO ENDOSURGERY INC | $11,932,000 | – | 3,268,948 | – | 1.86% | – |
| NPCE | New | NEUROPACE INC | $11,553,000 | – | 2,334,003 | – | 1.80% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $11,212,000 | – | 169,696 | – | 1.75% | – |
| TNDM | New | TANDEM DIABETES CARE INC | $10,879,000 | – | 183,800 | – | 1.70% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $9,731,000 | – | 841,018 | – | 1.52% | – |
| CUTR | New | CUTERA INC | $9,660,000 | – | 257,600 | – | 1.51% | – |
| EOLS | New | EVOLUS INC | $9,404,000 | – | 810,676 | – | 1.47% | – |
| BCAB | New | BIOATLA INC | $9,299,000 | – | 3,262,703 | – | 1.45% | – |
| ISEE | New | IVERIC BIO INC | $8,796,000 | – | 914,346 | – | 1.37% | – |
| PEN | New | PENUMBRA INC | $8,567,000 | – | 68,800 | – | 1.34% | – |
| PCVX | New | VAXCYTE INC | $8,065,000 | – | 370,650 | – | 1.26% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $7,944,000 | – | 719,600 | – | 1.24% | – |
| PIRS | New | PIERIS PHARMACEUTICALS INC | $7,732,000 | – | 4,134,868 | – | 1.21% | – |
| STE | New | STERIS PLC | $7,691,000 | – | 37,310 | – | 1.20% | – |
| SUPN | New | SUPERNUS PHARMACEUTICALS INC | $7,464,000 | – | 258,100 | – | 1.16% | – |
| CVRX | New | CVRX INC | $6,365,000 | – | 1,059,040 | – | 0.99% | – |
| HZNP | New | HORIZON THERAPEUTICS PUB L | $6,209,000 | – | 77,842 | – | 0.97% | – |
| INCY | New | INCYTE CORP | $6,055,000 | – | 79,700 | – | 0.94% | – |
| TMDX | New | TRANSMEDICS GROUP INC | $5,801,000 | – | 184,455 | – | 0.90% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $5,330,000 | – | 846,000 | – | 0.83% | – |
| STAA | New | STAAR SURGICAL CO | $5,326,000 | – | 75,094 | – | 0.83% | – |
| NARI | New | INARI MED INC | $4,916,000 | – | 72,298 | – | 0.77% | – |
| FATE | New | FATE THERAPEUTICS INC | $4,817,000 | – | 194,400 | – | 0.75% | – |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $4,727,000 | – | 100,000 | – | 0.74% | – |
| EXAS | New | EXACT SCIENCES CORP | $4,687,000 | – | 119,000 | – | 0.73% | – |
| NTRA | New | NATERA INC | $4,674,000 | – | 131,873 | – | 0.73% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $4,377,000 | – | 318,100 | – | 0.68% | – |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $4,263,000 | – | 78,400 | – | 0.66% | – |
| INMD | New | INMODE LTD | $4,201,000 | – | 187,449 | – | 0.66% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $3,925,000 | – | 490,000 | – | 0.61% | – |
| CCXI | New | CHEMOCENTRYX INC | $3,826,000 | – | 154,400 | – | 0.60% | – |
| CELC | New | CELCUITY INC | $3,812,000 | – | 418,912 | – | 0.60% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $3,815,000 | – | 196,018 | – | 0.60% | – |
| LNTH | New | LANTHEUS HLDGS INC | $3,646,000 | – | 55,222 | – | 0.57% | – |
| DXCM | New | DEXCOM INC | $3,520,000 | – | 47,236 | – | 0.55% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $3,347,000 | – | 592,417 | – | 0.52% | – |
| FGEN | New | FIBROGEN INC | $3,192,000 | – | 302,226 | – | 0.50% | – |
| New | IO BIOTECH INC | $3,061,000 | – | 655,404 | – | 0.48% | – | |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $2,932,000 | – | 20,100 | – | 0.46% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $2,282,000 | – | 75,000 | – | 0.36% | – |
| CCCC | New | C4 THERAPEUTICS INC | $2,131,000 | – | 282,640 | – | 0.33% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $2,084,000 | – | 252,000 | – | 0.32% | – |
| YMAB | New | Y-MABS THERAPEUTICS INC | $2,060,000 | – | 136,182 | – | 0.32% | – |
| VSTM | New | VERASTEM INC | $1,908,000 | – | 1,644,500 | – | 0.30% | – |
| New | PEPGEN INC | $1,738,000 | – | 175,000 | – | 0.27% | – | |
| KDNY | New | CHINOOK THERAPEUTICS INC | $1,539,000 | – | 88,000 | – | 0.24% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $1,337,000 | – | 22,000 | – | 0.21% | – |
| New | XILIO THERAPEUTICS INC | $1,325,000 | – | 453,660 | – | 0.21% | – | |
| CGEM | New | CULLINAN ONCOLOGY INC | $1,224,000 | – | 95,485 | – | 0.19% | – |
| New | BRIDGEBIO PHARMA INCnote 2.500% 3/1 | $1,068,000 | – | 1,950,000 | – | 0.17% | – | |
| OM | New | OUTSET MED INC | $1,028,000 | – | 69,200 | – | 0.16% | – |
| NVCR | New | NOVOCURE LTD | $923,000 | – | 13,275 | – | 0.14% | – |
| IMUX | New | IMMUNIC INC | $833,000 | – | 240,000 | – | 0.13% | – |
| VTGN | New | VISTAGEN THERAPEUTICS INC | $726,000 | – | 825,000 | – | 0.11% | – |
| New | DA32 LIFE SCNCE TEC ACQSTN C | $485,000 | – | 50,000 | – | 0.08% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| EWTX | Exit | EDGEWISE THERAPEUTICS INC | $0 | – | -31,300 | – | -0.08% | – |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -25,000 | – | -0.09% | – |
| BEAM | Exit | BEAM THERAPEUTICS INC | $0 | – | -7,700 | – | -0.10% | – |
| RFL | Exit | RAFAEL HLDGS INC | $0 | – | -21,742 | – | -0.10% | – |
| CUTR | Exit | CUTERA INC | $0 | – | -14,480 | – | -0.10% | – |
| Exit | PROCEPT BIOROBOTICS CORP | $0 | – | -20,000 | – | -0.12% | – | |
| NGM | Exit | NGM BIOPHARMACEUTICALS INC | $0 | – | -41,000 | – | -0.13% | – |
| EDIT | Exit | EDITAS MEDICINE INC | $0 | – | -23,500 | – | -0.15% | – |
| Exit | ASTRIA THERAPEUTICS INC | $0 | – | -112,499 | – | -0.16% | – | |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -261,050 | – | -0.21% | – |
| BVS | Exit | BIOVENTUS INC | $0 | – | -94,602 | – | -0.21% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -213,519 | – | -0.22% | – |
| CELC | Exit | CELCUITY INC | $0 | – | -83,688 | – | -0.24% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -215,576 | – | -0.31% | – |
| AXGN | Exit | AXOGEN INC | $0 | – | -158,140 | – | -0.39% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -171,000 | – | -0.40% | – |
| Exit | BRIDGEBIO PHARMA INCnote 2.500% 3/1 | $0 | – | -1,950,000 | – | -0.42% | – | |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -178,360 | – | -0.45% | – |
| CDMO | Exit | AVID BIOSERVICES INC | $0 | – | -135,000 | – | -0.45% | – |
| ARYD | Exit | ARYA SCIENCES ACQU CORP IVcl a | $0 | – | -300,000 | – | -0.47% | – |
| CORT | Exit | CORCEPT THERAPEUTICS INC | $0 | – | -155,000 | – | -0.48% | – |
| VIVO | Exit | MERIDIAN BIOSCIENCE INC | $0 | – | -163,000 | – | -0.49% | – |
| LUNG | Exit | PULMONX CORP | $0 | – | -87,612 | – | -0.49% | – |
| NVCR | Exit | NOVOCURE LTD | $0 | – | -27,275 | – | -0.49% | – |
| FDMT | Exit | 4D MOLECULAR THERAPEUTICS IN | $0 | – | -120,900 | – | -0.51% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -97,979 | – | -0.51% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -215,697 | – | -0.51% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -56,800 | – | -0.53% | – |
| Exit | DA32 LIFE SCNCE TEC ACQSTN C | $0 | – | -350,000 | – | -0.54% | – | |
| PCRX | Exit | PACIRA BIOSCIENCES INC | $0 | – | -66,000 | – | -0.58% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCsponsored ads | $0 | – | -127,743 | – | -0.60% | – |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -740,000 | – | -0.60% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -1,122,000 | – | -0.61% | – |
| AVIR | Exit | ATEA PHARMACEUTICALS INC | $0 | – | -117,600 | – | -0.64% | – |
| EOLS | Exit | EVOLUS INC | $0 | – | -642,934 | – | -0.76% | – |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -210,815 | – | -0.80% | – |
| VNDA | Exit | VANDA PHARMACEUTICALS INC | $0 | – | -298,600 | – | -0.80% | – |
| Exit | SOMALOGIC INC | $0 | – | -422,243 | – | -0.82% | – | |
| SKIN | Exit | THE BEAUTY HEALTH COMPANY | $0 | – | -201,994 | – | -0.82% | – |
| ITMR | Exit | ITAMAR MED LTDsponsored ads | $0 | – | -180,839 | – | -0.85% | – |
| GLPG | Exit | GALAPAGOS NVspon adr | $0 | – | -115,300 | – | -0.94% | – |
| ANGO | Exit | ANGIODYNAMICS INC | $0 | – | -242,525 | – | -0.98% | – |
| CTSO | Exit | CYTOSORBENTS CORP | $0 | – | -800,000 | – | -1.01% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -125,529 | – | -1.02% | – |
| INSP | Exit | INSPIRE MED SYS INC | $0 | – | -30,950 | – | -1.12% | – |
| YMAB | Exit | Y-MABS THERAPEUTICS INC | $0 | – | -265,700 | – | -1.18% | – |
| NRIX | Exit | NURIX THERAPEUTICS INC | $0 | – | -263,900 | – | -1.23% | – |
| CDNA | Exit | CAREDX INC | $0 | – | -126,661 | – | -1.25% | – |
| Exit | GOSSAMER BIO INCnote 5.000% 6/0 | $0 | – | -8,200,000 | – | -1.31% | – | |
| PCVX | Exit | VAXCYTE INC | $0 | – | -355,650 | – | -1.41% | – |
| ORGO | Exit | ORGANOGENESIS HLDGS INC | $0 | – | -639,887 | – | -1.42% | – |
| NEO | Exit | NEOGENOMICS INC | $0 | – | -190,556 | – | -1.43% | – |
| HOWL | Exit | WEREWOLF THERAPEUTICS INC | $0 | – | -563,396 | – | -1.51% | – |
| CVRX | Exit | CVRX INC | $0 | – | -619,065 | – | -1.60% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -92,214 | – | -1.61% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -182,400 | – | -1.62% | – |
| FLXN | Exit | FLEXION THERAPEUTICS INC | $0 | – | -2,084,050 | – | -1.98% | – |
| SIEN | Exit | SIENTRA INC | $0 | – | -2,386,063 | – | -2.13% | – |
| IRMD | Exit | IRADIMED CORP | $0 | – | -450,679 | – | -2.36% | – |
| NTRA | Exit | NATERA INC | $0 | – | -138,989 | – | -2.41% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -1,093,020 | – | -2.77% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -101,800 | – | -2.93% | – |
| EDAP | Exit | EDAP TMS S Asponsored adr | $0 | – | -2,956,367 | – | -2.94% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -319,396 | – | -2.99% | – |
| SRDX | Exit | SURMODICS INC | $0 | – | -381,522 | – | -3.31% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -2,868,023 | – | -3.58% | – |
| NPCE | Exit | NEUROPACE INC | $0 | – | -1,670,136 | – | -4.12% | – |
| THTX | Exit | THERATECHNOLOGIES INC | $0 | – | -7,612,383 | – | -4.45% | – |
| Exit | DICE THERAPEUTICS INC | $0 | – | -879,903 | – | -4.49% | – | |
| LNTH | Exit | LANTHEUS HLDGS INC | $0 | – | -1,229,827 | – | -4.92% | – |
| CCCC | Exit | C4 THERAPEUTICS INC | $0 | – | -750,633 | – | -5.23% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -2,515,424 | – | -11.54% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BCAB | Sell | BIOATLA INC | $74,054,000 | -37.5% | 2,515,424 | -10.0% | 11.54% | -36.6% |
| CCCC | Sell | C4 THERAPEUTICS INC | $33,538,000 | +1.8% | 750,633 | -13.8% | 5.23% | +3.1% |
| LNTH | Buy | LANTHEUS HLDGS INC | $31,582,000 | +25.1% | 1,229,827 | +34.6% | 4.92% | +26.7% |
| New | DICE THERAPEUTICS INC | $28,817,000 | – | 879,903 | – | 4.49% | – | |
| THTX | Buy | THERATECHNOLOGIES INC | $28,546,000 | +4.7% | 7,612,383 | +8.3% | 4.45% | +6.1% |
| NPCE | Buy | NEUROPACE INC | $26,472,000 | -19.6% | 1,670,136 | +20.6% | 4.12% | -18.6% |
| EPIX | Buy | ESSA PHARMA INC | $22,944,000 | -64.1% | 2,868,023 | +28.1% | 3.58% | -63.6% |
| SRDX | Buy | SURMODICS INC | $21,213,000 | +40.5% | 381,522 | +37.0% | 3.31% | +42.3% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $19,183,000 | +28.0% | 319,396 | +27.7% | 2.99% | +29.7% |
| EDAP | Buy | EDAP TMS S Asponsored adr | $18,862,000 | +3.3% | 2,956,367 | +14.7% | 2.94% | +4.6% |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $18,790,000 | – | 101,800 | – | 2.93% | – |
| ISEE | Sell | IVERIC BIO INC | $17,751,000 | +0.2% | 1,093,020 | -61.1% | 2.77% | +1.5% |
| NTRA | Buy | NATERA INC | $15,489,000 | +34.0% | 138,989 | +36.5% | 2.41% | +35.8% |
| IRMD | Sell | IRADIMED CORP | $15,138,000 | +3.5% | 450,679 | -9.4% | 2.36% | +4.9% |
| SIEN | Buy | SIENTRA INC | $13,672,000 | +17.5% | 2,386,063 | +63.3% | 2.13% | +19.1% |
| FLXN | New | FLEXION THERAPEUTICS INC | $12,713,000 | – | 2,084,050 | – | 1.98% | – |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $10,362,000 | – | 182,400 | – | 1.62% | – |
| CRSP | Sell | CRISPR THERAPEUTICS AGnamen akt | $10,322,000 | -38.2% | 92,214 | -10.6% | 1.61% | -37.4% |
| CVRX | Buy | CVRX INC | $10,239,000 | -14.2% | 619,065 | +45.2% | 1.60% | -13.1% |
| NEO | Sell | NEOGENOMICS INC | $9,192,000 | -42.2% | 190,556 | -45.9% | 1.43% | -41.4% |
| ORGO | New | ORGANOGENESIS HLDGS INC | $9,112,000 | – | 639,887 | – | 1.42% | – |
| PCVX | Sell | VAXCYTE INC | $9,023,000 | +6.7% | 355,650 | -5.3% | 1.41% | +8.2% |
| Sell | GOSSAMER BIO INCnote 5.000% 6/0 | $8,432,000 | -1.9% | 8,200,000 | -23.4% | 1.31% | -0.6% | |
| CDNA | Buy | CAREDX INC | $8,027,000 | +199.3% | 126,661 | +332.3% | 1.25% | +203.6% |
| NRIX | New | NURIX THERAPEUTICS INC | $7,906,000 | – | 263,900 | – | 1.23% | – |
| YMAB | Buy | Y-MABS THERAPEUTICS INC | $7,583,000 | +55.5% | 265,700 | +84.1% | 1.18% | +57.6% |
| INSP | Buy | INSPIRE MED SYS INC | $7,208,000 | +73.1% | 30,950 | +43.6% | 1.12% | +75.5% |
| KRYS | Buy | KRYSTAL BIOTECH INC | $6,554,000 | +42.7% | 125,529 | +85.9% | 1.02% | +44.6% |
| CTSO | New | CYTOSORBENTS CORP | $6,496,000 | – | 800,000 | – | 1.01% | – |
| ANGO | New | ANGIODYNAMICS INC | $6,291,000 | – | 242,525 | – | 0.98% | – |
| GLPG | New | GALAPAGOS NVspon adr | $6,066,000 | – | 115,300 | – | 0.94% | – |
| ITMR | Sell | ITAMAR MED LTDsponsored ads | $5,465,000 | -56.3% | 180,839 | -65.9% | 0.85% | -55.7% |
| SKIN | Sell | THE BEAUTY HEALTH COMPANY | $5,246,000 | -66.6% | 201,994 | -78.4% | 0.82% | -66.2% |
| New | SOMALOGIC INC | $5,232,000 | – | 422,243 | – | 0.82% | – | |
| VNDA | New | VANDA PHARMACEUTICALS INC | $5,118,000 | – | 298,600 | – | 0.80% | – |
| TVTX | New | TRAVERE THERAPEUTICS INC | $5,112,000 | – | 210,815 | – | 0.80% | – |
| EOLS | Buy | EVOLUS INC | $4,899,000 | -33.2% | 642,934 | +10.9% | 0.76% | -32.4% |
| AVIR | New | ATEA PHARMACEUTICALS INC | $4,123,000 | – | 117,600 | – | 0.64% | – |
| PIRS | New | PIERIS PHARMACEUTICALS INC | $3,826,000 | – | 740,000 | – | 0.60% | – |
| PCRX | New | PACIRA BIOSCIENCES INC | $3,696,000 | – | 66,000 | – | 0.58% | – |
| New | DA32 LIFE SCNCE TEC ACQSTN C | $3,441,000 | – | 350,000 | – | 0.54% | – | |
| ARNA | New | ARENA PHARMACEUTICALS INC | $3,382,000 | – | 56,800 | – | 0.53% | – |
| XENE | Sell | XENON PHARMACEUTICALS INC | $3,296,000 | -24.2% | 215,697 | -7.7% | 0.51% | -23.2% |
| INBX | Sell | INHIBRX INC | $3,264,000 | -51.2% | 97,979 | -59.6% | 0.51% | -50.5% |
| FDMT | Buy | 4D MOLECULAR THERAPEUTICS IN | $3,261,000 | +34.4% | 120,900 | +19.9% | 0.51% | +36.2% |
| NVCR | Sell | NOVOCURE LTD | $3,169,000 | -85.6% | 27,275 | -72.4% | 0.49% | -85.4% |
| LUNG | Buy | PULMONX CORP | $3,152,000 | -16.2% | 87,612 | +2.8% | 0.49% | -15.1% |
| VIVO | New | MERIDIAN BIOSCIENCE INC | $3,136,000 | – | 163,000 | – | 0.49% | – |
| CORT | New | CORCEPT THERAPEUTICS INC | $3,050,000 | – | 155,000 | – | 0.48% | – |
| CDMO | New | AVID BIOSERVICES INC | $2,912,000 | – | 135,000 | – | 0.45% | – |
| ZGNX | New | ZOGENIX INC | $2,597,000 | – | 171,000 | – | 0.40% | – |
| LYRA | Buy | LYRA THERAPEUTICS INC | $1,967,000 | +33.8% | 215,576 | +17.8% | 0.31% | +35.8% |
| CELC | Sell | CELCUITY INC | $1,506,000 | -61.9% | 83,688 | -49.2% | 0.24% | -61.3% |
| BVS | New | BIOVENTUS INC | $1,340,000 | – | 94,602 | – | 0.21% | – |
| CTMX | New | CYTOMX THERAPEUTICS INC | $1,329,000 | – | 261,050 | – | 0.21% | – |
| New | ASTRIA THERAPEUTICS INC | $994,000 | – | 112,499 | – | 0.16% | – | |
| EDIT | Sell | EDITAS MEDICINE INC | $965,000 | -82.2% | 23,500 | -75.4% | 0.15% | -82.0% |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $862,000 | – | 41,000 | – | 0.13% | – |
| New | PROCEPT BIOROBOTICS CORP | $763,000 | – | 20,000 | – | 0.12% | – | |
| CUTR | Sell | CUTERA INC | $675,000 | -86.6% | 14,480 | -85.9% | 0.10% | -86.5% |
| RFL | Sell | RAFAEL HLDGS INC | $668,000 | -64.4% | 21,742 | -40.8% | 0.10% | -63.9% |
| BEAM | Sell | BEAM THERAPEUTICS INC | $670,000 | -76.4% | 7,700 | -65.2% | 0.10% | -76.2% |
| GLUE | Sell | MONTE ROSA THERAPEUTICS INC | $557,000 | -67.3% | 25,000 | -66.7% | 0.09% | -66.8% |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -7,300 | – | -0.04% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -86,442 | – | -0.05% | – |
| NARI | Exit | INARI MED INC | $0 | – | -6,150 | – | -0.09% | – |
| TCRR | Exit | TCR2 THERAPEUTICS INC | $0 | – | -47,537 | – | -0.12% | – |
| MGTA | Exit | MAGENTA THERAPEUTICS INC | $0 | – | -90,000 | – | -0.14% | – |
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -31,306 | – | -0.15% | – |
| RNLX | Exit | RENALYTIX PLCads | $0 | – | -47,300 | – | -0.22% | – |
| CMAX | Exit | CAREMAX INC | $0 | – | -118,900 | – | -0.24% | – |
| Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -775,000 | – | -0.25% | – | |
| HALO | Exit | HALOZYME THERAPEUTICS INC | $0 | – | -44,100 | – | -0.31% | – |
| GH | Exit | GUARDANT HEALTH INC | $0 | – | -17,500 | – | -0.33% | – |
| MSON | Exit | MISONIX INC | $0 | – | -100,788 | – | -0.34% | – |
| ESTA | Exit | ESTABLISHMENT LABS HLDGS INC | $0 | – | -26,568 | – | -0.36% | – |
| PODD | Exit | INSULET CORP | $0 | – | -8,980 | – | -0.38% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -5,884 | – | -0.39% | – |
| TKNO | Exit | ALPHA TEKNOVA INC | $0 | – | -114,546 | – | -0.42% | – |
| GLTO | Exit | GALECTO INC | $0 | – | -538,152 | – | -0.42% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -125,700 | – | -0.61% | – |
| MDXG | Exit | MIMEDX GROUP INC | $0 | – | -322,160 | – | -0.62% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BCAB | New | BIOATLA INC | $118,420,000 | – | 2,794,233 | – | 18.21% | – |
| EPIX | New | ESSA PHARMA INC | $63,943,000 | – | 2,238,104 | – | 9.83% | – |
| CCCC | New | C4 THERAPEUTICS INC | $32,949,000 | – | 870,758 | – | 5.07% | – |
| NPCE | New | NEUROPACE INC | $32,935,000 | – | 1,384,387 | – | 5.06% | – |
| THTX | New | THERATECHNOLOGIES INC | $27,269,000 | – | 7,028,096 | – | 4.19% | – |
| LNTH | New | LANTHEUS HLDGS INC | $25,255,000 | – | 913,697 | – | 3.88% | – |
| NVCR | New | NOVOCURE LTD | $21,955,000 | – | 98,975 | – | 3.38% | – |
| EDAP | New | EDAP TMS S Asponsored adr | $18,267,000 | – | 2,576,401 | – | 2.81% | – |
| ISEE | New | IVERIC BIO INC | $17,721,000 | – | 2,808,343 | – | 2.72% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $16,693,000 | – | 103,114 | – | 2.57% | – |
| NEO | New | NEOGENOMICS INC | $15,900,000 | – | 352,007 | – | 2.44% | – |
| SKIN | New | THE BEAUTY HEALTH COMPANY | $15,697,000 | – | 934,316 | – | 2.41% | – |
| SRDX | New | SURMODICS INC | $15,103,000 | – | 278,404 | – | 2.32% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $14,984,000 | – | 250,146 | – | 2.30% | – |
| IRMD | New | IRADIMED CORP | $14,622,000 | – | 497,179 | – | 2.25% | – |
| ITMR | New | ITAMAR MED LTDsponsored ads | $12,501,000 | – | 530,839 | – | 1.92% | – |
| CVRX | New | CVRX INC | $11,939,000 | – | 426,394 | – | 1.84% | – |
| SIEN | New | SIENTRA INC | $11,634,000 | – | 1,461,563 | – | 1.79% | – |
| NTRA | New | NATERA INC | $11,562,000 | – | 101,839 | – | 1.78% | – |
| HOWL | New | WEREWOLF THERAPEUTICS INC | $9,826,000 | – | 563,396 | – | 1.51% | – |
| New | GOSSAMER BIO INCnote 5.000% 6/0 | $8,596,000 | – | 10,700,000 | – | 1.32% | – | |
| PCVX | New | VAXCYTE INC | $8,456,000 | – | 375,650 | – | 1.30% | – |
| EOLS | New | EVOLUS INC | $7,337,000 | – | 580,000 | – | 1.13% | – |
| INBX | New | INHIBRX INC | $6,682,000 | – | 242,789 | – | 1.03% | – |
| EDIT | New | EDITAS MEDICINE INC | $5,415,000 | – | 95,600 | – | 0.83% | – |
| CUTR | New | CUTERA INC | $5,049,000 | – | 102,980 | – | 0.78% | – |
| YMAB | New | Y-MABS THERAPEUTICS INC | $4,877,000 | – | 144,300 | – | 0.75% | – |
| CMPS | New | COMPASS PATHWAYS PLCsponsored ads | $4,873,000 | – | 127,743 | – | 0.75% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $4,592,000 | – | 67,529 | – | 0.71% | – |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $4,353,000 | – | 1,122,000 | – | 0.67% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $4,351,000 | – | 233,697 | – | 0.67% | – |
| INSP | New | INSPIRE MED SYS INC | $4,165,000 | – | 21,550 | – | 0.64% | – |
| MDXG | New | MIMEDX GROUP INC | $4,030,000 | – | 322,160 | – | 0.62% | – |
| RVMD | New | REVOLUTION MEDICINES INC | $3,990,000 | – | 125,700 | – | 0.61% | – |
| CELC | New | CELCUITY INC | $3,956,000 | – | 164,824 | – | 0.61% | – |
| LUNG | New | PULMONX CORP | $3,761,000 | – | 85,250 | – | 0.58% | – |
| DYN | New | DYNE THERAPEUTICS INC | $3,753,000 | – | 178,360 | – | 0.58% | – |
| AXGN | New | AXOGEN INC | $3,417,000 | – | 158,140 | – | 0.52% | – |
| ARYD | New | ARYA SCIENCES ACQU CORP IVcl a | $3,216,000 | – | 300,000 | – | 0.50% | – |
| New | BRIDGEBIO PHARMA INCnote 2.500% 3/1 | $3,201,000 | – | 1,950,000 | – | 0.49% | – | |
| BEAM | New | BEAM THERAPEUTICS INC | $2,844,000 | – | 22,100 | – | 0.44% | – |
| GLTO | New | GALECTO INC | $2,723,000 | – | 538,152 | – | 0.42% | – |
| TKNO | New | ALPHA TEKNOVA INC | $2,718,000 | – | 114,546 | – | 0.42% | – |
| CDNA | New | CAREDX INC | $2,682,000 | – | 29,300 | – | 0.41% | – |
| DXCM | New | DEXCOM INC | $2,512,000 | – | 5,884 | – | 0.39% | – |
| PODD | New | INSULET CORP | $2,465,000 | – | 8,980 | – | 0.38% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $2,427,000 | – | 100,800 | – | 0.37% | – |
| ESTA | New | ESTABLISHMENT LABS HLDGS INC | $2,320,000 | – | 26,568 | – | 0.36% | – |
| MSON | New | MISONIX INC | $2,235,000 | – | 100,788 | – | 0.34% | – |
| GH | New | GUARDANT HEALTH INC | $2,173,000 | – | 17,500 | – | 0.33% | – |
| HALO | New | HALOZYME THERAPEUTICS INC | $2,003,000 | – | 44,100 | – | 0.31% | – |
| RFL | New | RAFAEL HLDGS INC | $1,876,000 | – | 36,742 | – | 0.29% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,819,000 | – | 213,519 | – | 0.28% | – |
| GLUE | New | MONTE ROSA THERAPEUTICS INC | $1,703,000 | – | 75,000 | – | 0.26% | – |
| New | CATABASIS PHARMACEUTICALS IN | $1,635,000 | – | 775,000 | – | 0.25% | – | |
| CMAX | New | CAREMAX INC | $1,534,000 | – | 118,900 | – | 0.24% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $1,470,000 | – | 183,076 | – | 0.23% | – |
| RNLX | New | RENALYTIX PLCads | $1,460,000 | – | 47,300 | – | 0.22% | – |
| SBTX | New | SILVERBACK THERAPEUTICS INC | $967,000 | – | 31,306 | – | 0.15% | – |
| MGTA | New | MAGENTA THERAPEUTICS INC | $880,000 | – | 90,000 | – | 0.14% | – |
| TCRR | New | TCR2 THERAPEUTICS INC | $780,000 | – | 47,537 | – | 0.12% | – |
| EWTX | New | EDGEWISE THERAPEUTICS INC | $668,000 | – | 31,300 | – | 0.10% | – |
| NARI | New | INARI MED INC | $574,000 | – | 6,150 | – | 0.09% | – |
| KDMN | New | KADMON HLDGS INC | $335,000 | – | 86,442 | – | 0.05% | – |
| RPTX | New | REPARE THERAPEUTICS INC | $228,000 | – | 7,300 | – | 0.04% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UMRX | Exit | UNUM THERAPEUTICS INC | $0 | – | -47,900 | – | -0.06% | – |
| Exit | INSMED INCnote 1.750% 1/1 | $0 | – | -180,000 | – | -0.10% | – | |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -10,742 | – | -0.12% | – |
| AFMD | Exit | AFFIMED N V | $0 | – | -68,493 | – | -0.12% | – |
| IRTC | Exit | IRHYTHM TECHNOLOGIES INC | $0 | – | -1,187 | – | -0.15% | – |
| CSTL | Exit | CASTLE BIOSCIENCES INC | $0 | – | -6,269 | – | -0.17% | – |
| FATE | Exit | FATE THERAPEUTICS INC | $0 | – | -9,712 | – | -0.21% | – |
| KYMR | Exit | KYMERA THERAPEUTICS INC | $0 | – | -15,305 | – | -0.26% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -9,203 | – | -0.27% | – |
| ENTA | Exit | ENANTA PHARMACEUTICALS INC | $0 | – | -11,500 | – | -0.28% | – |
| PCRX | Exit | PACIRA BIOSCIENCES | $0 | – | -10,200 | – | -0.32% | – |
| HARP | Exit | HARPOON THERAPEUTICS INC | $0 | – | -42,472 | – | -0.38% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -167,798 | – | -0.38% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -200,841 | – | -0.42% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -10,977 | – | -0.44% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -10,200 | – | -0.45% | – |
| PODD | Exit | INSULET CORP | $0 | – | -3,632 | – | -0.46% | – |
| STAA | Exit | STAAR SURGICAL CO | $0 | – | -15,346 | – | -0.46% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -19,648 | – | -0.49% | – |
| Exit | GOSSAMER BIO INCnote 5.000% 6/0 | $0 | – | -1,000,000 | – | -0.54% | – | |
| MDNA | Exit | MEDICENNA THERAPEUTICS CORP | $0 | – | -248,860 | – | -0.55% | – |
| PIRS | Exit | PIERIS PHARMACEUTICALS INC | $0 | – | -500,000 | – | -0.55% | – |
| RVNC | Exit | REVANCE THERAPEUTICS INC | $0 | – | -41,617 | – | -0.55% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -76,184 | – | -0.61% | – |
| LYRA | Exit | LYRA THERAPEUTICS INC | $0 | – | -110,670 | – | -0.66% | – |
| AXGN | Exit | AXOGEN INC | $0 | – | -135,111 | – | -0.83% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -112,742 | – | -0.85% | – | |
| RFL | Exit | RAFAEL HLDGS INC | $0 | – | -104,737 | – | -0.86% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -11,926 | – | -0.88% | – |
| TARA | Exit | PROTARA THERAPEUTICS INC | $0 | – | -100,000 | – | -0.89% | – |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -139,418 | – | -0.95% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -20,454 | – | -1.00% | – |
| ZYXI | Exit | ZYNEX INC | $0 | – | -118,047 | – | -1.09% | – |
| MRK | Exit | MERCK & CO. INC | $0 | – | -26,579 | – | -1.17% | – |
| AXNX | Exit | AXONICS MODULATION TECHNOLOG | $0 | – | -54,089 | – | -1.46% | – |
| ITMR | Exit | ITAMAR MED LTDsponsored ads | $0 | – | -140,524 | – | -1.52% | – |
| MSON | Exit | MISONIX INC | $0 | – | -250,253 | – | -1.56% | – |
| SRDX | Exit | SURMODICS INC | $0 | – | -77,283 | – | -1.59% | – |
| DXCM | Exit | DEXCOM INC | $0 | – | -7,583 | – | -1.66% | – |
| OSH | Exit | OAK STR HEALTH INC | $0 | – | -58,892 | – | -1.67% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -11,556 | – | -1.74% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -30,077 | – | -1.82% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -364,349 | – | -1.99% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -472,558 | – | -2.04% | – |
| CRDF | Exit | CARDIFF ONCOLOGY INC | $0 | – | -281,819 | – | -2.12% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -52,227 | – | -2.15% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -89,233 | – | -2.20% | – |
| IRMD | Exit | IRADIMED CORP | $0 | – | -198,739 | – | -2.25% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCsponsored ads | $0 | – | -156,982 | – | -2.90% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -500,264 | – | -2.94% | – |
| TCRR | Exit | TCR2 THERAPEUTICS INC | $0 | – | -282,041 | – | -3.04% | – |
| NVCR | Exit | NOVOCURE LTD | $0 | – | -52,377 | – | -3.09% | – |
| LNTH | Exit | LANTHEUS HLDGS INC | $0 | – | -509,544 | – | -3.42% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -46,166 | – | -3.44% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -76,268 | – | -3.44% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -353,006 | – | -3.47% | – |
| QDEL | Exit | QUIDEL CORP | $0 | – | -30,751 | – | -3.58% | – |
| NTRA | Exit | NATERA INC | $0 | – | -101,089 | – | -3.87% | – |
| INBX | Exit | INHIBRX INC | $0 | – | -406,500 | – | -3.88% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -393,041 | – | -3.88% | – |
| OSUR | Exit | ORASURE TECHNOLOGIES INC | $0 | – | -625,109 | – | -4.03% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -1,685,879 | – | -5.04% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -1,826,980 | – | -6.68% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| EPIX | Sell | ESSA PHARMA INC | $12,606,000 | -2.3% | 1,826,980 | -12.3% | 6.68% | -9.2% |
| ISEE | Buy | IVERIC BIO INC | $9,508,000 | +14.6% | 1,685,879 | +3.6% | 5.04% | +6.6% |
| OSUR | Buy | ORASURE TECHNOLOGIES INC | $7,608,000 | +193.2% | 625,109 | +180.1% | 4.03% | +172.7% |
| MRSN | New | MERSANA THERAPEUTICS INC | $7,318,000 | – | 393,041 | – | 3.88% | – |
| INBX | New | INHIBRX INC | $7,317,000 | – | 406,500 | – | 3.88% | – |
| NTRA | New | NATERA INC | $7,303,000 | – | 101,089 | – | 3.87% | – |
| QDEL | Sell | QUIDEL CORP | $6,746,000 | -2.4% | 30,751 | -0.5% | 3.58% | -9.3% |
| VCEL | Buy | VERICEL CORP | $6,540,000 | +98.4% | 353,006 | +48.0% | 3.47% | +84.5% |
| IMMU | Sell | IMMUNOMEDICS INC | $6,485,000 | +53.8% | 76,268 | -35.9% | 3.44% | +43.0% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $6,483,000 | +17.2% | 46,166 | +33.8% | 3.44% | +9.0% |
| LNTH | New | LANTHEUS HLDGS INC | $6,456,000 | – | 509,544 | – | 3.42% | – |
| NVCR | Sell | NOVOCURE LTD | $5,830,000 | +74.3% | 52,377 | -7.1% | 3.09% | +62.1% |
| TCRR | New | TCR2 THERAPEUTICS INC | $5,731,000 | – | 282,041 | – | 3.04% | – |
| XENE | Buy | XENON PHARMACEUTICALS INC | $5,538,000 | +76.0% | 500,264 | +99.4% | 2.94% | +63.7% |
| CMPS | New | COMPASS PATHWAYS PLCsponsored ads | $5,479,000 | – | 156,982 | – | 2.90% | – |
| IRMD | Sell | IRADIMED CORP | $4,249,000 | -13.8% | 198,739 | -6.4% | 2.25% | -19.9% |
| ZYME | Sell | ZYMEWORKS INC | $4,156,000 | -72.6% | 89,233 | -78.8% | 2.20% | -74.5% |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $4,057,000 | +146.6% | 52,227 | +76.4% | 2.15% | +129.3% |
| CRDF | New | CARDIFF ONCOLOGY INC | $3,999,000 | – | 281,819 | – | 2.12% | – |
| EIGR | Sell | EIGER BIOPHARMACEUTICALS INC | $3,847,000 | -35.4% | 472,558 | -23.8% | 2.04% | -39.9% |
| ADVM | Buy | ADVERUM BIOTECHNOLOGIES INC | $3,753,000 | -17.8% | 364,349 | +66.6% | 1.99% | -23.6% |
| ALXN | Sell | ALEXION PHARMACEUTICALS INC | $3,442,000 | -39.6% | 30,077 | -40.8% | 1.82% | -43.8% |
| BIIB | Buy | BIOGEN INC | $3,278,000 | +433.0% | 11,556 | +402.4% | 1.74% | +395.2% |
| OSH | New | OAK STR HEALTH INC | $3,147,000 | – | 58,892 | – | 1.67% | – |
| DXCM | Sell | DEXCOM INC | $3,126,000 | -19.2% | 7,583 | -20.6% | 1.66% | -24.9% |
| SRDX | Buy | SURMODICS INC | $3,007,000 | +58.2% | 77,283 | +75.7% | 1.59% | +47.0% |
| MSON | Buy | MISONIX INC | $2,935,000 | +10.2% | 250,253 | +27.5% | 1.56% | +2.5% |
| AXNX | Buy | AXONICS MODULATION TECHNOLOG | $2,761,000 | +61.2% | 54,089 | +10.8% | 1.46% | +49.8% |
| MRK | New | MERCK & CO. INC | $2,205,000 | – | 26,579 | – | 1.17% | – |
| ZYXI | Sell | ZYNEX INC | $2,060,000 | -53.1% | 118,047 | -33.1% | 1.09% | -56.4% |
| BPMC | New | BLUEPRINT MEDICINES CORP | $1,896,000 | – | 20,454 | – | 1.00% | – |
| PRVB | Buy | PROVENTION BIO INC | $1,789,000 | +111.7% | 139,418 | +132.8% | 0.95% | +96.7% |
| TARA | New | PROTARA THERAPEUTICS INC | $1,683,000 | – | 100,000 | – | 0.89% | – |
| NVRO | Sell | NEVRO CORP | $1,661,000 | -26.0% | 11,926 | -36.6% | 0.88% | -31.2% |
| New | TRILLIUM THERAPEUTICS INC | $1,602,000 | – | 112,742 | – | 0.85% | – | |
| AXGN | Buy | AXOGEN INC | $1,571,000 | +111.7% | 135,111 | +68.2% | 0.83% | +96.9% |
| LYRA | Buy | LYRA THERAPEUTICS INC | $1,237,000 | +80.1% | 110,670 | +82.4% | 0.66% | +67.3% |
| LRMR | Buy | LARIMAR THERAPEUTICS INC | $1,156,000 | +189.0% | 76,184 | +144.4% | 0.61% | +168.9% |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $1,046,000 | +50.5% | 41,617 | +46.2% | 0.55% | +39.9% |
| PIRS | New | PIERIS PHARMACEUTICALS INC | $1,035,000 | – | 500,000 | – | 0.55% | – |
| MDNA | New | MEDICENNA THERAPEUTICS CORP | $1,030,000 | – | 248,860 | – | 0.55% | – |
| IONS | Sell | IONIS PHARMACEUTICALS INC | $932,000 | -56.6% | 19,648 | -46.0% | 0.49% | -59.6% |
| STAA | Sell | STAAR SURGICAL CO | $868,000 | -30.9% | 15,346 | -24.9% | 0.46% | -35.8% |
| PODD | Sell | INSULET CORP | $859,000 | +10.6% | 3,632 | -9.2% | 0.46% | +2.7% |
| CRSP | Sell | CRISPR THERAPEUTICS AGnamen akt | $853,000 | -32.5% | 10,200 | -40.7% | 0.45% | -37.3% |
| ARNA | New | ARENA PHARMACEUTICALS INC | $821,000 | – | 10,977 | – | 0.44% | – |
| DVAX | Buy | DYNAVAX TECHNOLOGIES CORP | $725,000 | -18.3% | 167,798 | +67.8% | 0.38% | -24.1% |
| HARP | Buy | HARPOON THERAPEUTICS INC | $722,000 | +41.0% | 42,472 | +37.5% | 0.38% | +31.2% |
| PCRX | Sell | PACIRA BIOSCIENCES | $613,000 | -4.2% | 10,200 | -16.4% | 0.32% | -11.0% |
| AZN | Sell | ASTRAZENECA PLCsponsored adr | $504,000 | -93.0% | 9,203 | -93.2% | 0.27% | -93.5% |
| KYMR | New | KYMERA THERAPEUTICS INC | $495,000 | – | 15,305 | – | 0.26% | – |
| FATE | Sell | FATE THERAPEUTICS INC | $388,000 | -65.7% | 9,712 | -70.6% | 0.21% | -68.1% |
| CSTL | Sell | CASTLE BIOSCIENCES INC | $323,000 | -42.8% | 6,269 | -58.2% | 0.17% | -46.9% |
| IRTC | New | IRHYTHM TECHNOLOGIES INC | $283,000 | – | 1,187 | – | 0.15% | – |
| AFMD | New | AFFIMED N V | $232,000 | – | 68,493 | – | 0.12% | – |
| CNST | Sell | CONSTELLATION PHARMCETICLS I | $218,000 | -78.3% | 10,742 | -67.8% | 0.12% | -79.7% |
| UMRX | New | UNUM THERAPEUTICS INC | $112,000 | – | 47,900 | – | 0.06% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -6,000 | – | -0.12% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -6,900 | – | -0.18% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -15,100 | – | -0.25% | – |
| INSP | Exit | INSPIRE MED SYS INC | $0 | – | -5,608 | – | -0.28% | – |
| ATRS | Exit | ANTARES PHARMA INC | $0 | – | -229,046 | – | -0.36% | – |
| MASI | Exit | MASIMO CORP | $0 | – | -3,400 | – | -0.44% | – |
| VAPO | Exit | VAPOTHERM INC | $0 | – | -21,700 | – | -0.51% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO L | $0 | – | -14,000 | – | -0.58% | – |
| SILK | Exit | SILK RD MED INC | $0 | – | -27,711 | – | -0.66% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -127,300 | – | -1.09% | – |
| HUM | Exit | HUMANA INC | $0 | – | -6,600 | – | -1.46% | – |
| ABBV | Exit | ABBVIE INC | $0 | – | -28,900 | – | -1.62% | – |
| NARI | Exit | INARI MED INC | $0 | – | -65,817 | – | -1.82% | – |
| LLY | Exit | LILLY ELI & CO | $0 | – | -20,800 | – | -1.95% | – |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -369,852 | – | -1.95% | – |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -674,603 | – | -4.02% | – |
| ZYME | Exit | ZYMEWORKS INCput | $0 | – | -327,900 | – | -6.74% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ZYME | New | ZYMEWORKS INC | $15,179,000 | – | 420,836 | – | 8.65% | – |
| EPIX | New | ESSA PHARMA INC | $12,909,000 | – | 2,082,185 | – | 7.36% | – |
| ZYME | New | ZYMEWORKS INCput | $11,827,000 | – | 327,900 | – | 6.74% | – |
| ISEE | New | IVERIC BIO INC | $8,296,000 | – | 1,626,701 | – | 4.73% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $7,204,000 | – | 136,214 | – | 4.11% | – |
| PRTA | New | PROTHENA CORP PLC | $7,056,000 | – | 674,603 | – | 4.02% | – |
| QDEL | New | QUIDEL CORP | $6,913,000 | – | 30,900 | – | 3.94% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $5,954,000 | – | 620,266 | – | 3.39% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $5,700,000 | – | 50,789 | – | 3.25% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $5,531,000 | – | 34,500 | – | 3.15% | – |
| IRMD | New | IRADIMED CORP | $4,930,000 | – | 212,436 | – | 2.81% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $4,566,000 | – | 218,723 | – | 2.60% | – |
| ZYXI | New | ZYNEX INC | $4,390,000 | – | 176,541 | – | 2.50% | – |
| IMMU | New | IMMUNOMEDICS INC | $4,217,000 | – | 119,000 | – | 2.40% | – |
| DXCM | New | DEXCOM INC | $3,871,000 | – | 9,550 | – | 2.21% | – |
| AGLE | New | AEGLEA BIOTHERAPEUTICS INC | $3,421,000 | – | 369,852 | – | 1.95% | – |
| LLY | New | LILLY ELI & CO | $3,414,000 | – | 20,800 | – | 1.95% | – |
| NVCR | New | NOVOCURE LTD | $3,344,000 | – | 56,397 | – | 1.91% | – |
| VCEL | New | VERICEL CORP | $3,296,000 | – | 238,532 | – | 1.88% | – |
| NARI | New | INARI MED INC | $3,188,000 | – | 65,817 | – | 1.82% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $3,146,000 | – | 250,897 | – | 1.79% | – |
| ABBV | New | ABBVIE INC | $2,837,000 | – | 28,900 | – | 1.62% | – |
| MSON | New | MISONIX INC | $2,663,000 | – | 196,301 | – | 1.52% | – |
| ITMR | New | ITAMAR MED LTDsponsored ads | $2,613,000 | – | 140,524 | – | 1.49% | – |
| OSUR | New | ORASURE TECHNOLOGIES INC | $2,595,000 | – | 223,200 | – | 1.48% | – |
| HUM | New | HUMANA INC | $2,559,000 | – | 6,600 | – | 1.46% | – |
| NVRO | New | NEVRO CORP | $2,246,000 | – | 18,800 | – | 1.28% | – |
| IONS | New | IONIS PHARMACEUTICALS INC | $2,146,000 | – | 36,400 | – | 1.22% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $1,919,000 | – | 127,300 | – | 1.09% | – |
| SRDX | New | SURMODICS INC | $1,901,000 | – | 43,978 | – | 1.08% | – |
| AXNX | New | AXONICS MODULATION TECHNOLOG | $1,713,000 | – | 48,800 | – | 0.98% | – |
| HZNP | New | HORIZON THERAPEUTICS PUB LTD | $1,645,000 | – | 29,600 | – | 0.94% | – |
| RFL | New | RAFAEL HLDGS INC | $1,505,000 | – | 104,737 | – | 0.86% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $1,264,000 | – | 17,200 | – | 0.72% | – |
| STAA | New | STAAR SURGICAL CO | $1,257,000 | – | 20,428 | – | 0.72% | – |
| SILK | New | SILK RD MED INC | $1,160,000 | – | 27,711 | – | 0.66% | – |
| FATE | New | FATE THERAPEUTICS INC | $1,132,000 | – | 33,000 | – | 0.64% | – |
| KDMN | New | KADMON HLDGS INC | $1,028,000 | – | 200,841 | – | 0.59% | – |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $1,023,000 | – | 14,000 | – | 0.58% | – |
| CNST | New | CONSTELLATION PHARMCETICLS I | $1,003,000 | – | 33,400 | – | 0.57% | – |
| New | GOSSAMER BIO INCnote 5.000% 6/0 | $1,001,000 | – | 1,000,000 | – | 0.57% | – | |
| VAPO | New | VAPOTHERM INC | $889,000 | – | 21,700 | – | 0.51% | – |
| DVAX | New | DYNAVAX TECHNOLOGIES CORP | $887,000 | – | 100,000 | – | 0.51% | – |
| PRVB | New | PROVENTION BIO INC | $845,000 | – | 59,900 | – | 0.48% | – |
| PODD | New | INSULET CORP | $777,000 | – | 4,000 | – | 0.44% | – |
| MASI | New | MASIMO CORP | $775,000 | – | 3,400 | – | 0.44% | – |
| AXGN | New | AXOGEN INC | $742,000 | – | 80,350 | – | 0.42% | – |
| RVNC | New | REVANCE THERAPEUTICS INC | $695,000 | – | 28,469 | – | 0.40% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $687,000 | – | 60,670 | – | 0.39% | – |
| PCRX | New | PACIRA BIOSCIENCES | $640,000 | – | 12,200 | – | 0.36% | – |
| ATRS | New | ANTARES PHARMA INC | $629,000 | – | 229,046 | – | 0.36% | – |
| BIIB | New | BIOGEN INC | $615,000 | – | 2,300 | – | 0.35% | – |
| ENTA | New | ENANTA PHARMACEUTICALS INC | $577,000 | – | 11,500 | – | 0.33% | – |
| CSTL | New | CASTLE BIOSCIENCES INC | $565,000 | – | 15,000 | – | 0.32% | – |
| HARP | New | HARPOON THERAPEUTICS INC | $512,000 | – | 30,886 | – | 0.29% | – |
| INSP | New | INSPIRE MED SYS INC | $488,000 | – | 5,608 | – | 0.28% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $438,000 | – | 15,100 | – | 0.25% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $400,000 | – | 31,170 | – | 0.23% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $308,000 | – | 6,900 | – | 0.18% | – |
| ARVN | New | ARVINAS INC | $201,000 | – | 6,000 | – | 0.12% | – |
| New | INSMED INCnote 1.750% 1/1 | $174,000 | – | 180,000 | – | 0.10% | – |