Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PLRX | Sell | PLIANT THERAPEUTICS INC | $52,266,211 | -7.5% | 3,014,199 | -3.3% | 20.72% | +20.9% |
| RPTX | Sell | REPARE THERAPEUTICS INC | $35,837,422 | +13.0% | 2,966,674 | -1.1% | 14.20% | +47.5% |
| Sell | ACELYRIN INC | $23,014,608 | -58.7% | 2,262,990 | -15.0% | 9.12% | -46.0% | |
| Buy | ORCHARD THERAPEUTICS PLCspon ads new | $14,034,773 | +256.4% | 12,315,654 | +1529.6% | 5.56% | +365.5% | |
| KROS | Buy | KEROS THERAPEUTICS INC | $12,995,340 | -19.6% | 407,633 | +1.4% | 5.15% | +5.1% |
| IKNA | Buy | IKENA ONCOLOGY INC | $9,443,445 | -32.2% | 2,180,934 | +2.8% | 3.74% | -11.4% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $7,664,750 | +95.5% | 215,000 | +152.9% | 3.04% | +155.3% |
| New | MINERALYS THERAPEUTICS INC | $5,405,284 | – | 568,379 | – | 2.14% | – | |
| INZY | Buy | INOZYME PHARMA INC | $5,334,112 | -19.9% | 1,270,027 | +6.3% | 2.11% | +4.7% |
| Buy | SYROS PHARMACEUTICALS INC | $5,119,170 | +111.8% | 1,299,359 | +69.3% | 2.03% | +176.4% | |
| BPMC | New | BLUEPRINT MEDICINES CORP | $4,664,835 | – | 92,888 | – | 1.85% | – |
| LABD | Sell | DIREXION SHS ETF TRdaily s&p biotec | $4,635,000 | -0.8% | 225,000 | -30.8% | 1.84% | +29.6% |
| Buy | 2SEVENTY BIO INC | $3,927,867 | -54.4% | 1,002,007 | +17.6% | 1.56% | -40.5% | |
| New | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $3,420,000 | – | 60,000 | – | 1.36% | – | |
| New | SAGIMET BIOSCIENCES INC | $3,069,810 | – | 348,842 | – | 1.22% | – | |
| BDTX | Sell | BLACK DIAMOND THERAPEUTICS I | $2,066,400 | -45.4% | 720,000 | -4.0% | 0.82% | -28.7% |
| Sell | RALLYBIO CORP | $1,316,774 | -57.1% | 390,734 | -28.0% | 0.52% | -44.0% | |
| Sell | DISC MEDICINE INC | $1,174,500 | -78.9% | 25,000 | -80.0% | 0.47% | -72.4% | |
| Buy | FREELINE THERAPEUTICS HLDGSsponsored ads | $372,613 | +566.6% | 86,654 | +300.0% | 0.15% | +770.6% | |
| DTIL | Sell | PRECISION BIOSCIENCES INC | $207,043 | -75.5% | 606,629 | -62.2% | 0.08% | -68.0% |
| RPTX | New | REPARE THERAPEUTICS INCcall | $157,500 | – | 50,000 | – | 0.06% | – |
| PLRX | Buy | PLIANT THERAPEUTICS INCcall | $55,000 | -66.0% | 137,500 | +5.5% | 0.02% | -55.1% |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -200,000 | – | -0.14% | – |
| HOOK | Exit | HOOKIPA PHARMA INC | $0 | – | -788,740 | – | -0.21% | – |
| VECT | Exit | VECTIVBIO HLDG AG | $0 | – | -2,782,756 | – | -14.24% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PLRX | New | PLIANT THERAPEUTICS INC | $56,480,348 | – | 3,117,017 | – | 17.14% | – |
| New | ACELYRIN INC | $55,673,548 | – | 2,663,806 | – | 16.89% | – | |
| VECT | New | VECTIVBIO HLDG AG | $46,945,093 | – | 2,782,756 | – | 14.24% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $36,736,673 | – | 3,414,189 | – | 11.15% | – |
| RPTX | New | REPARE THERAPEUTICS INC | $31,726,606 | – | 2,998,734 | – | 9.63% | – |
| KROS | New | KEROS THERAPEUTICS INC | $16,157,101 | – | 402,118 | – | 4.90% | – |
| IKNA | New | IKENA ONCOLOGY INC | $13,920,582 | – | 2,122,040 | – | 4.22% | – |
| CMPX | New | COMPASS THERAPEUTICS INC | $8,998,484 | – | 2,829,712 | – | 2.73% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $8,720,383 | – | 3,414,468 | – | 2.65% | – |
| New | 2SEVENTY BIO INC | $8,622,311 | – | 852,007 | – | 2.62% | – | |
| INZY | New | INOZYME PHARMA INC | $6,656,301 | – | 1,195,027 | – | 2.02% | – |
| New | OMEGA THERAPEUTICS INC | $5,912,938 | – | 1,055,882 | – | 1.79% | – | |
| New | DISC MEDICINE INC | $5,556,172 | – | 125,139 | – | 1.69% | – | |
| LABD | New | DIREXION SHS ETF TRdaily s&p biotec | $4,670,250 | – | 325,000 | – | 1.42% | – |
| New | ORCHARD THERAPEUTICS PLCspon ads new | $3,937,394 | – | 755,738 | – | 1.20% | – | |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $3,921,050 | – | 85,000 | – | 1.19% | – |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $3,787,500 | – | 750,000 | – | 1.15% | – |
| New | RALLYBIO CORP | $3,072,101 | – | 542,774 | – | 0.93% | – | |
| OVID | New | OVID THERAPEUTICS INC | $2,836,616 | – | 864,822 | – | 0.86% | – |
| New | SYROS PHARMACEUTICALS INC | $2,417,452 | – | 767,445 | – | 0.73% | – | |
| DTIL | New | PRECISION BIOSCIENCES INC | $843,471 | – | 1,603,557 | – | 0.26% | – |
| HOOK | New | HOOKIPA PHARMA INC | $694,091 | – | 788,740 | – | 0.21% | – |
| GRPH | New | GRAPHITE BIO INC | $600,439 | – | 230,938 | – | 0.18% | – |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $458,000 | – | 200,000 | – | 0.14% | – |
| PLRX | New | PLIANT THERAPEUTICS INCcall | $161,828 | – | 130,300 | – | 0.05% | – |
| New | FREELINE THERAPEUTICS HLDGSsponsored ads | $55,898 | – | 21,666 | – | 0.02% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LABD | Exit | DIREXION SHS ETF TRdaily s&p biotec | $0 | – | -50,000 | – | -0.32% | – |
| NKTX | Exit | NKARTA INC | $0 | – | -117,599 | – | -0.42% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -864,822 | – | -0.43% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -2,384,402 | – | -0.52% | – |
| ONCR | Exit | ONCORUS INC | $0 | – | -2,367,436 | – | -0.54% | – |
| Exit | RALLYBIO CORP | $0 | – | -194,297 | – | -0.76% | – | |
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -4,814,419 | – | -0.91% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -455,100 | – | -0.92% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCspon ads | $0 | – | -7,987,396 | – | -1.07% | – |
| GTHX | Exit | G1 THERAPEUTICS INC | $0 | – | -323,945 | – | -1.09% | – |
| IKNA | Exit | IKENA ONCOLOGY INC | $0 | – | -1,214,304 | – | -1.16% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -3,674,820 | – | -1.28% | – |
| INZY | Exit | INOZYME PHARMA INC | $0 | – | -1,996,277 | – | -1.44% | – |
| Exit | OMEGA THERAPEUTICS INC | $0 | – | -1,055,882 | – | -1.54% | – | |
| CMPX | Exit | COMPASS THERAPEUTICS INC | $0 | – | -2,829,712 | – | -1.74% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -200,229 | – | -2.03% | – |
| Exit | 2SEVENTY BIO INC | $0 | – | -530,223 | – | -2.07% | – | |
| AKUS | Exit | AKOUOS INC | $0 | – | -1,288,358 | – | -2.34% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -3,415,148 | – | -2.94% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -1,762,793 | – | -4.08% | – |
| VECT | Exit | VECTIVBIO HLDG AG | $0 | – | -4,119,572 | – | -6.65% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -3,069,847 | – | -10.01% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -3,243,185 | – | -11.18% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -3,409,758 | – | -19.15% | – |
| RXDX | Exit | PROMETHEUS BIOSCIENCES INC | $0 | – | -1,601,785 | – | -25.42% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $94,521,000 | +100.3% | 1,601,785 | -4.2% | 25.42% | +41.0% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $71,230,000 | +186.2% | 3,409,758 | +9.8% | 19.15% | +101.5% |
| CGEM | Buy | CULLINAN ONCOLOGY INC | $41,578,000 | +6.4% | 3,243,185 | +6.4% | 11.18% | -25.1% |
| RPTX | Buy | REPARE THERAPEUTICS INC | $37,237,000 | +0.6% | 3,069,847 | +16.0% | 10.01% | -29.2% |
| VECT | Buy | VECTIVBIO HLDG AG | $24,717,000 | +21.0% | 4,119,572 | +8.9% | 6.65% | -14.8% |
| KZR | Sell | KEZAR LIFE SCIENCES INC | $15,178,000 | -0.3% | 1,762,793 | -4.2% | 4.08% | -29.8% |
| LRMR | Buy | LARIMAR THERAPEUTICS INC | $10,928,000 | +267.9% | 3,415,148 | +125.4% | 2.94% | +159.1% |
| AKUS | Buy | AKOUOS INC | $8,709,000 | +122.1% | 1,288,358 | +54.1% | 2.34% | +56.3% |
| Sell | 2SEVENTY BIO INC | $7,715,000 | -28.7% | 530,223 | -35.3% | 2.07% | -49.8% | |
| KROS | Buy | KEROS THERAPEUTICS INC | $7,533,000 | +163.6% | 200,229 | +93.6% | 2.03% | +85.5% |
| INZY | Sell | INOZYME PHARMA INC | $5,350,000 | -44.9% | 1,996,277 | -1.8% | 1.44% | -61.2% |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $4,777,000 | -0.6% | 3,674,820 | +22.3% | 1.28% | -30.1% |
| IKNA | Buy | IKENA ONCOLOGY INC | $4,311,000 | -10.8% | 1,214,304 | +11.3% | 1.16% | -37.2% |
| GTHX | Sell | G1 THERAPEUTICS INC | $4,046,000 | +6.8% | 323,945 | -57.8% | 1.09% | -24.8% |
| ORTX | Buy | ORCHARD THERAPEUTICS PLCspon ads | $3,994,000 | +28.8% | 7,987,396 | +50.5% | 1.07% | -9.3% |
| EIGR | Buy | EIGER BIOPHARMACEUTICALS INC | $3,427,000 | +186.3% | 455,100 | +139.5% | 0.92% | +101.5% |
| FRLN | Sell | FREELINE THERAPEUTICS HLDGSsponsored ads | $3,370,000 | -20.3% | 4,814,419 | -1.0% | 0.91% | -43.9% |
| New | RALLYBIO CORP | $2,811,000 | – | 194,297 | – | 0.76% | – | |
| CRVS | Buy | CORVUS PHARMACEUTICALS INC | $1,952,000 | -10.9% | 2,384,402 | +7.7% | 0.52% | -37.3% |
| NKTX | Sell | NKARTA INC | $1,548,000 | -64.9% | 117,599 | -67.2% | 0.42% | -75.3% |
| LABD | New | DIREXION SHS ETF TRdaily s&p biotec | $1,197,000 | – | 50,000 | – | 0.32% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INCcall | $0 | – | -100,000 | – | -0.00% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INCcall | $0 | – | -25,100 | – | -0.00% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -157,000 | – | -0.14% | – |
| PHAS | Exit | PHASEBIO PHARMACEUTICALS INC | $0 | – | -750,000 | – | -0.17% | – |
| Exit | ENTRADA THERAPEUTICS INC | $0 | – | -163,496 | – | -0.76% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $47,200,000 | – | 1,671,976 | – | 18.03% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $39,070,000 | – | 3,047,609 | – | 14.92% | – |
| RPTX | New | REPARE THERAPEUTICS INC | $37,028,000 | – | 2,646,781 | – | 14.14% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $24,886,000 | – | 3,106,807 | – | 9.50% | – |
| VECT | New | VECTIVBIO HLDG AG | $20,424,000 | – | 3,782,199 | – | 7.80% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $15,223,000 | – | 1,840,793 | – | 5.81% | – |
| New | 2SEVENTY BIO INC | $10,820,000 | – | 819,672 | – | 4.13% | – | |
| INZY | New | INOZYME PHARMA INC | $9,701,000 | – | 2,033,802 | – | 3.70% | – |
| CMPX | New | COMPASS THERAPEUTICS INC | $7,499,000 | – | 2,829,712 | – | 2.86% | – |
| IKNA | New | IKENA ONCOLOGY INC | $4,833,000 | – | 1,090,937 | – | 1.85% | – |
| DTIL | New | PRECISION BIOSCIENCES INC | $4,806,000 | – | 3,003,751 | – | 1.84% | – |
| NKTX | New | NKARTA INC | $4,411,000 | – | 358,013 | – | 1.68% | – |
| FRLN | New | FREELINE THERAPEUTICS HLDGSsponsored ads | $4,230,000 | – | 4,862,319 | – | 1.62% | – |
| New | OMEGA THERAPEUTICS INC | $4,012,000 | – | 1,055,882 | – | 1.53% | – | |
| AKUS | New | AKOUOS INC | $3,921,000 | – | 836,120 | – | 1.50% | – |
| GTHX | New | G1 THERAPEUTICS INC | $3,790,000 | – | 767,235 | – | 1.45% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $3,101,000 | – | 5,307,751 | – | 1.18% | – |
| ONCR | New | ONCORUS INC | $2,983,000 | – | 2,367,436 | – | 1.14% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $2,970,000 | – | 1,515,148 | – | 1.13% | – |
| KROS | New | KEROS THERAPEUTICS INC | $2,858,000 | – | 103,429 | – | 1.09% | – |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $2,192,000 | – | 2,214,184 | – | 0.84% | – |
| New | ENTRADA THERAPEUTICS INC | $1,991,000 | – | 163,496 | – | 0.76% | – | |
| OVID | New | OVID THERAPEUTICS INC | $1,859,000 | – | 864,822 | – | 0.71% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INC | $1,197,000 | – | 190,000 | – | 0.46% | – |
| PHAS | New | PHASEBIO PHARMACEUTICALS INC | $450,000 | – | 750,000 | – | 0.17% | – |
| XBI | New | SPDR SER TRput | $372,000 | – | 157,000 | – | 0.14% | – |
| EIGR | New | EIGER BIOPHARMACEUTICALS INCcall | $4,000 | – | 25,100 | – | 0.00% | – |
| KZR | New | KEZAR LIFE SCIENCES INCcall | $5,000 | – | 100,000 | – | 0.00% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -12,627 | – | -0.15% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -75,000 | – | -0.19% | – |
| GTHX | Exit | G1 THERAPEUTICS INC | $0 | – | -50,000 | – | -0.20% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -233,510 | – | -0.23% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -165,927 | – | -0.23% | – |
| IKNA | Exit | IKENA ONCOLOGY INC | $0 | – | -315,000 | – | -1.16% | – |
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -1,427,481 | – | -1.42% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -646,729 | – | -2.18% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -4,081,972 | – | -2.74% | – |
| AKUS | Exit | AKOUOS INC | $0 | – | -858,027 | – | -2.91% | – |
| INZY | Exit | INOZYME PHARMA INC | $0 | – | -920,264 | – | -3.11% | – |
| ONCR | Exit | ONCORUS INC | $0 | – | -1,755,979 | – | -4.79% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -1,515,148 | – | -5.10% | – |
| Exit | OMEGA THERAPEUTICS INC | $0 | – | -1,055,882 | – | -5.81% | – | |
| VECT | Exit | VECTIVBIO HLDG AG | $0 | – | -2,592,602 | – | -5.85% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -2,484,724 | – | -12.24% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -2,244,841 | – | -14.79% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -2,232,783 | – | -17.10% | – |
| RXDX | Exit | PROMETHEUS BIOSCIENCES INC | $0 | – | -2,862,059 | – | -19.81% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RXDX | Buy | PROMETHEUS BIOSCIENCES INC | $67,859,000 | -3.1% | 2,862,059 | +0.4% | 19.81% | +21.6% |
| RPTX | Sell | REPARE THERAPEUTICS INC | $58,588,000 | -26.0% | 2,232,783 | -12.1% | 17.10% | -7.2% |
| CGEM | Buy | CULLINAN ONCOLOGY INC | $50,666,000 | -12.3% | 2,244,841 | +0.1% | 14.79% | +10.1% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $41,942,000 | -39.2% | 2,484,724 | +4.9% | 12.24% | -23.7% |
| VECT | Buy | VECTIVBIO HLDG AG | $20,028,000 | -33.6% | 2,592,602 | +0.3% | 5.85% | -16.7% |
| New | OMEGA THERAPEUTICS INC | $19,904,000 | – | 1,055,882 | – | 5.81% | – | |
| ONCR | Buy | ONCORUS INC | $16,401,000 | -31.5% | 1,755,979 | +1.2% | 4.79% | -14.1% |
| INZY | Sell | INOZYME PHARMA INC | $10,666,000 | -32.5% | 920,264 | -0.8% | 3.11% | -15.3% |
| DTIL | Sell | PRECISION BIOSCIENCES INC | $7,463,000 | -8.5% | 646,729 | -0.8% | 2.18% | +14.8% |
| FRLN | Buy | FREELINE THERAPEUTICS HLDGSsponsored ads | $4,867,000 | -56.7% | 1,427,481 | +3.5% | 1.42% | -45.7% |
| IKNA | Sell | IKENA ONCOLOGY INC | $3,975,000 | -65.3% | 315,000 | -61.3% | 1.16% | -56.4% |
| CRVS | Sell | CORVUS PHARMACEUTICALS INC | $803,000 | -58.2% | 165,927 | -76.9% | 0.23% | -47.7% |
| OVID | Buy | OVID THERAPEUTICS INC | $785,000 | -8.1% | 233,510 | +6.9% | 0.23% | +15.1% |
| KZR | Sell | KEZAR LIFE SCIENCES INC | $648,000 | -18.6% | 75,000 | -48.9% | 0.19% | +2.2% |
| KROS | Sell | KEROS THERAPEUTICS INC | $500,000 | -89.9% | 12,627 | -89.2% | 0.15% | -87.3% |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RPTX | New | REPARE THERAPEUTICS INC | $79,186,000 | – | 2,539,644 | – | 18.42% | – |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $70,046,000 | – | 2,852,009 | – | 16.30% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $68,953,000 | – | 2,367,888 | – | 16.04% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $57,753,000 | – | 2,242,841 | – | 13.44% | – |
| VECT | New | VECTIVBIO HLDG AG | $30,152,000 | – | 2,585,986 | – | 7.01% | – |
| ONCR | New | ONCORUS INC | $23,956,000 | – | 1,735,979 | – | 5.57% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $17,919,000 | – | 4,081,972 | – | 4.17% | – |
| INZY | New | INOZYME PHARMA INC | $15,801,000 | – | 927,264 | – | 3.68% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $14,879,000 | – | 1,515,148 | – | 3.46% | – |
| IKNA | New | IKENA ONCOLOGY INC | $11,440,000 | – | 814,756 | – | 2.66% | – |
| FRLN | New | FREELINE THERAPEUTICS HLDGSsponsored ads | $11,246,000 | – | 1,379,843 | – | 2.62% | – |
| AKUS | New | AKOUOS INC | $10,768,000 | – | 858,027 | – | 2.50% | – |
| DTIL | New | PRECISION BIOSCIENCES INC | $8,160,000 | – | 651,729 | – | 1.90% | – |
| KROS | New | KEROS THERAPEUTICS INC | $4,944,000 | – | 116,406 | – | 1.15% | – |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $1,920,000 | – | 719,132 | – | 0.45% | – |
| GTHX | New | G1 THERAPEUTICS INC | $1,097,000 | – | 50,000 | – | 0.26% | – |
| OVID | New | OVID THERAPEUTICS INC | $854,000 | – | 218,510 | – | 0.20% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $796,000 | – | 146,680 | – | 0.18% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INcall | $0 | – | -10,000 | – | -0.01% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -8,000 | – | -0.15% | – |
| LVGO | Exit | LIVONGO HEALTH INC | $0 | – | -3,640 | – | -0.18% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -6,500 | – | -0.22% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -7,500 | – | -0.22% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -70,000 | – | -0.26% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -16,000 | – | -0.31% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -7,000 | – | -0.34% | – |
| GTHX | Exit | G1 THERAPEUTICS INC | $0 | – | -84,000 | – | -0.34% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -246,643 | – | -0.42% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -583,232 | – | -0.83% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -618,092 | – | -1.26% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -1,014,840 | – | -2.22% | – |
| AMWL | Exit | AMERICAN WELL CORPcl a | $0 | – | -248,352 | – | -2.62% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -2,931,185 | – | -4.29% | – |
| AKUS | Exit | AKOUOS INC | $0 | – | -846,397 | – | -6.89% | – |
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -1,324,364 | – | -7.35% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -569,458 | – | -7.81% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -1,515,148 | – | -8.18% | – |
| INZY | Exit | INOZYME PHARMA INC | $0 | – | -1,009,117 | – | -9.44% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -2,352,291 | – | -18.95% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -2,530,494 | – | -27.70% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RPTX | Buy | REPARE THERAPEUTICS INC | $77,863,000 | +0.3% | 2,530,494 | +1.1% | 27.70% | -8.6% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $53,279,000 | -28.8% | 2,352,291 | +2.0% | 18.95% | -35.1% |
| INZY | New | INOZYME PHARMA INC | $26,529,000 | – | 1,009,117 | – | 9.44% | – |
| KROS | Sell | KEROS THERAPEUTICS INC | $21,964,000 | +1.0% | 569,458 | -1.8% | 7.81% | -7.9% |
| FRLN | New | FREELINE THERAPEUTICS HLDGSsponsored ads | $20,673,000 | – | 1,324,364 | – | 7.35% | – |
| AKUS | Sell | AKOUOS INC | $19,357,000 | -11.8% | 846,397 | -13.2% | 6.89% | -19.6% |
| AMWL | New | AMERICAN WELL CORPcl a | $7,361,000 | – | 248,352 | – | 2.62% | – |
| DTIL | Buy | PRECISION BIOSCIENCES INC | $6,251,000 | -21.8% | 1,014,840 | +5.7% | 2.22% | -28.7% |
| OVID | Buy | OVID THERAPEUTICS INC | $3,548,000 | -11.5% | 618,092 | +13.6% | 1.26% | -19.4% |
| CRVS | Buy | CORVUS PHARMACEUTICALS INC | $2,339,000 | +136.3% | 583,232 | +60.2% | 0.83% | +115.5% |
| KZR | Sell | KEZAR LIFE SCIENCES INC | $1,194,000 | -32.4% | 246,643 | -27.7% | 0.42% | -38.3% |
| GTHX | Buy | G1 THERAPEUTICS INC | $970,000 | -9.1% | 84,000 | +90.9% | 0.34% | -17.1% |
| MYOK | Sell | MYOKARDIA INC | $954,000 | -26.8% | 7,000 | -48.1% | 0.34% | -33.4% |
| GBT | Buy | GLOBAL BLOOD THERAPEUTICS IN | $882,000 | +7.4% | 16,000 | +23.1% | 0.31% | -1.9% |
| ADVM | Buy | ADVERUM BIOTECHNOLOGIES INC | $721,000 | -30.9% | 70,000 | +40.0% | 0.26% | -37.1% |
| RARE | Sell | ULTRAGENYX PHARMACEUTICAL IN | $616,000 | -39.4% | 7,500 | -42.3% | 0.22% | -44.8% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $603,000 | -35.6% | 6,500 | -45.8% | 0.22% | -41.1% |
| LVGO | Sell | LIVONGO HEALTH INC | $510,000 | -54.8% | 3,640 | -75.7% | 0.18% | -58.9% |
| GBT | New | GLOBAL BLOOD THERAPEUTICS INcall | $26,000 | – | 10,000 | – | 0.01% | – |
| UMRX | Exit | UNUM THERAPEUTICS INC | $0 | – | -940,805 | – | -0.17% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RPTX | New | REPARE THERAPEUTICS INC | $77,656,000 | – | 2,503,408 | – | 30.30% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $74,853,000 | – | 2,305,994 | – | 29.21% | – |
| AKUS | New | AKOUOS INC | $21,938,000 | – | 974,985 | – | 8.56% | – |
| KROS | New | KEROS THERAPEUTICS INC | $21,746,000 | – | 579,744 | – | 8.49% | – |
| LRMR | New | LARIMAR THERAPEUTICS INC | $19,470,000 | – | 1,515,148 | – | 7.60% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $17,587,000 | – | 2,931,185 | – | 6.86% | – |
| DTIL | New | PRECISION BIOSCIENCES INC | $7,997,000 | – | 960,040 | – | 3.12% | – |
| OVID | New | OVID THERAPEUTICS INC | $4,011,000 | – | 544,281 | – | 1.56% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $1,766,000 | – | 340,973 | – | 0.69% | – |
| MYOK | New | MYOKARDIA INC | $1,304,000 | – | 13,500 | – | 0.51% | – |
| LVGO | New | LIVONGO HEALTH INC | $1,128,000 | – | 15,000 | – | 0.44% | – |
| GTHX | New | G1 THERAPEUTICS INC | $1,067,000 | – | 44,000 | – | 0.42% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $1,044,000 | – | 50,000 | – | 0.41% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $1,017,000 | – | 13,000 | – | 0.40% | – |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $990,000 | – | 364,132 | – | 0.39% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $936,000 | – | 12,000 | – | 0.36% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $821,000 | – | 13,000 | – | 0.32% | – |
| BLUE | New | BLUEBIRD BIO INC | $488,000 | – | 8,000 | – | 0.19% | – |
| UMRX | New | UNUM THERAPEUTICS INC | $433,000 | – | 940,805 | – | 0.17% | – |
Q4 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -148,092 | – | -0.47% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -35,000 | – | -0.96% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -24,000 | – | -1.00% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -12,000 | – | -1.07% | – |
| UMRX | Exit | UNUM THERAPEUTICS INC | $0 | – | -790,805 | – | -1.11% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -22,464 | – | -1.14% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -390,307 | – | -1.14% | – |
| BPMC | Exit | BLUEPRINT MEDICINES CORP | $0 | – | -18,000 | – | -1.29% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -28,000 | – | -1.32% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -727,260 | – | -2.29% | – |
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -1,083,786 | – | -8.85% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -2,990,211 | – | -34.58% | – |
| LVGO | Exit | LIVONGO HEALTH INC | $0 | – | -2,636,640 | – | -44.76% | – |
Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LVGO | New | LIVONGO HEALTH INC | $45,983,000 | – | 2,636,640 | – | 44.76% | – |
| ORTX | New | ORCHARD THERAPEUTICS PLCads | $35,524,000 | – | 2,990,211 | – | 34.58% | – |
| DTIL | New | PRECISION BIOSCIENCES INC | $9,093,000 | – | 1,083,786 | – | 8.85% | – |
| OVID | New | OVID THERAPEUTICS INC | $2,356,000 | – | 727,260 | – | 2.29% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $1,359,000 | – | 28,000 | – | 1.32% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $1,322,000 | – | 18,000 | – | 1.29% | – |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $1,175,000 | – | 390,307 | – | 1.14% | – |
| MYOK | New | MYOKARDIA INC | $1,171,000 | – | 22,464 | – | 1.14% | – |
| UMRX | New | UNUM THERAPEUTICS INC | $1,139,000 | – | 790,805 | – | 1.11% | – |
| BLUE | New | BLUEBIRD BIO INC | $1,102,000 | – | 12,000 | – | 1.07% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $1,027,000 | – | 24,000 | – | 1.00% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $983,000 | – | 35,000 | – | 0.96% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $486,000 | – | 148,092 | – | 0.47% | – |