$671 Million is the total value of Ikarian Capital, LLC's 186 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 53.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | Sell | SPDR SER TRput | $60,727,000 | -25.7% | 542,400 | -16.6% | 9.05% | +57.2% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INCcall | $30,237,000 | -10.9% | 178,300 | -0.8% | 4.50% | +88.4% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB Lcall | $26,607,000 | -42.4% | 246,900 | -41.5% | 3.96% | +21.8% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEWcall | $22,946,000 | -46.3% | 593,800 | -25.0% | 3.42% | +13.6% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEWput | $17,433,000 | -37.9% | 451,200 | -13.3% | 2.60% | +31.3% |
| GOSS | Sell | GOSSAMER BIO INC | $13,199,000 | -22.3% | 1,166,933 | -13.7% | 1.97% | +64.2% |
| SRRA | Sell | SIERRA ONCOLOGY INC | $12,370,000 | -1.6% | 569,029 | -0.8% | 1.84% | +108.2% |
| XBI | Sell | SPDR SER TRcall | $10,345,000 | -72.6% | 92,400 | -69.2% | 1.54% | -42.0% |
| IMTX | Sell | IMMATICS N.V | $9,913,000 | -13.6% | 737,546 | -16.5% | 1.48% | +82.8% |
| APLS | Sell | APELLIS PHARMACEUTICALS INCcall | $9,455,000 | +23.1% | 200,000 | -14.2% | 1.41% | +160.3% |
| BIIB | Sell | BIOGEN INC | $7,087,000 | -22.3% | 29,533 | -8.4% | 1.06% | +64.5% |
| INBX | Sell | INHIBRX INC | $6,542,000 | -32.2% | 149,850 | -48.3% | 0.98% | +43.4% |
| XENE | Sell | XENON PHARMACEUTICALS INC | $5,597,000 | -2.9% | 179,138 | -52.5% | 0.83% | +105.4% |
| XFOR | Sell | X4 PHARMACEUTICALS INC | $5,186,000 | -61.4% | 2,264,491 | -10.8% | 0.77% | -18.3% |
| CMRX | Sell | CHIMERIX INC | $5,114,000 | +3.1% | 795,410 | -0.7% | 0.76% | +118.3% |
| CABA | Sell | CABALETTA BIO INC | $3,678,000 | -74.5% | 970,398 | -18.3% | 0.55% | -46.1% |
| Sell | RENOVACOR INC | $2,641,000 | -34.1% | 342,902 | -22.6% | 0.39% | +39.4% | |
| RETA | Sell | REATA PHARMACEUTICALS INCput | $2,637,000 | -94.4% | 100,000 | -78.8% | 0.39% | -88.2% |
| MGNX | Sell | MACROGENICS INC | $2,506,000 | -36.5% | 156,047 | -17.2% | 0.37% | +34.2% |
| OVID | Sell | OVID THERAPEUTICS INC | $2,264,000 | -39.1% | 705,082 | -36.2% | 0.34% | +28.6% |
| ARNA | Sell | ARENA PHARMACEUTICALS INCcall | $2,072,000 | -76.6% | 22,300 | -85.0% | 0.31% | -50.4% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $1,896,000 | -52.0% | 164,174 | -60.4% | 0.28% | +1.4% |
| TARA | Sell | PROTARA THERAPEUTICS INC | $1,885,000 | -43.2% | 279,256 | -41.8% | 0.28% | +20.1% |
| CMMB | Sell | CHEMOMAB THERAPEUTICS LTDsponsored ads | $1,829,000 | -42.1% | 265,264 | -7.0% | 0.27% | +22.0% |
| ODT | Sell | ODONATE THERAPEUTICS INC | $1,810,000 | -66.2% | 1,340,631 | -27.2% | 0.27% | -28.4% |
| LYRA | Sell | LYRA THERAPEUTICS INC | $1,719,000 | -53.4% | 394,536 | -2.2% | 0.26% | -1.5% |
| LQDA | Sell | LIQUIDIA CORPORATION | $1,583,000 | -35.2% | 325,445 | -63.2% | 0.24% | +37.2% |
| IFRX | Sell | INFLARX NV | $1,577,000 | -3.5% | 331,048 | -47.5% | 0.24% | +104.3% |
| PHAT | Sell | PHATHOM PHARMACEUTICALS INC | $1,467,000 | -54.1% | 74,560 | -25.1% | 0.22% | -2.7% |
| Sell | MAXCYTE INC | $1,325,000 | -27.6% | 130,000 | -13.3% | 0.20% | +52.7% | |
| VSTM | Sell | VERASTEM INC | $1,308,000 | -65.4% | 637,371 | -48.1% | 0.20% | -26.7% |
| SNPX | Sell | SYNAPTOGENIX INC | $1,239,000 | -49.2% | 145,629 | -40.7% | 0.18% | +7.6% |
| SYBX | Sell | SYNLOGIC INC | $1,171,000 | -51.3% | 483,818 | -38.7% | 0.17% | +3.0% |
| CRVS | Sell | CORVUS PHARMACEUTICALS INC | $1,163,000 | -68.3% | 482,610 | -36.3% | 0.17% | -32.9% |
| VTGN | Sell | VISTAGEN THERAPEUTICS INC | $927,000 | -43.7% | 475,693 | -20.8% | 0.14% | +19.0% |
| NXTC | Sell | NEXTCURE INC | $804,000 | -76.6% | 134,055 | -73.7% | 0.12% | -50.4% |
| ISEE | Sell | IVERIC BIO INC | $778,000 | -77.9% | 46,519 | -78.5% | 0.12% | -53.2% |
| DMAC | Sell | DIAMEDICA THERAPEUTICS INC | $779,000 | -37.5% | 209,082 | -32.8% | 0.12% | +31.8% |
| CDAK | Sell | CODIAK BIOSCIENCES INC | $554,000 | -71.7% | 49,680 | -58.6% | 0.08% | -39.9% |
| Sell | ALTAMIRA THERAPEUTICS LTD | $553,000 | -31.1% | 304,791 | -23.6% | 0.08% | +43.9% | |
| RFL | Sell | RAFAEL HLDGS INCput | $510,000 | -96.0% | 100,000 | -75.8% | 0.08% | -91.5% |
| KALV | Sell | KALVISTA PHARMACEUTICALS INC | $484,000 | -71.3% | 36,576 | -62.1% | 0.07% | -39.5% |
| BLU | Sell | BELLUS HEALTH INC NEW | $402,000 | -91.2% | 50,000 | -93.3% | 0.06% | -81.4% |
| MREO | Sell | MEREO BIOPHARMA GROUP PLCads | $307,000 | -4.7% | 853,680 | -5.5% | 0.05% | +100.0% |
| EYPT | Sell | EYEPOINT PHARMACEUTICALS INC | $262,000 | -31.1% | 21,427 | -41.2% | 0.04% | +44.4% |
| LIFE | Sell | ATYR PHARMA INC | $262,000 | -94.9% | 35,048 | -93.8% | 0.04% | -89.1% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $204,000 | -26.1% | 1,195 | -18.2% | 0.03% | +57.9% |
| OCUL | Sell | OCULAR THERAPEUTIX INC | $191,000 | -93.1% | 27,551 | -90.1% | 0.03% | -85.6% |
| ASLN | Sell | ASLAN PHARMACEUTICALS LTDads | $187,000 | -35.1% | 917,348 | -35.3% | 0.03% | +40.0% |
| ACRS | Sell | ACLARIS THERAPEUTICS INC | $156,000 | -79.7% | 10,785 | -74.7% | 0.02% | -57.4% |
| IGMS | Sell | IGM BIOSCIENCES INC | $44,000 | -98.7% | 1,500 | -97.1% | 0.01% | -97.1% |
| ACAD | Sell | ACADIA PHARMACEUTICALS INC | $42,000 | -99.1% | 1,765 | -99.4% | 0.01% | -98.2% |
| FLACU | Sell | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $9,000 | -98.8% | 941 | -98.7% | 0.00% | -98.0% |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -30,727 | -100.0% | -0.02% | – |
| DCTH | Exit | DELCATH SYS INC | $0 | – | -44,857 | -100.0% | -0.03% | – |
| INMB | Exit | INMUNE BIO INC | $0 | – | -26,632 | -100.0% | -0.04% | – |
| KLDO | Exit | KALEIDO BIOSCIENCES INC | $0 | – | -100,000 | -100.0% | -0.04% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -6,496 | -100.0% | -0.04% | – |
| KNSA | Exit | KINIKSA PHARMACEUTICALS LTD | $0 | – | -59,422 | -100.0% | -0.05% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -83,046 | -100.0% | -0.05% | – |
| STTK | Exit | SHATTUCK LABS INC | $0 | – | -36,240 | -100.0% | -0.05% | – |
| AVIR | Exit | ATEA PHARMACEUTICALS INCput | $0 | – | -22,800 | -100.0% | -0.06% | – |
| ASND | Exit | ASCENDIS PHARMA A/Scall | $0 | – | -8,400 | -100.0% | -0.09% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -53,370 | -100.0% | -0.11% | – |
| CRTX | Exit | CORTEXYME INC | $0 | – | -20,160 | -100.0% | -0.13% | – |
| HSAQ | Exit | HEALTH SCIENCES ACQ CORP 2 | $0 | – | -197,173 | -100.0% | -0.14% | – |
| EDIT | Exit | EDITAS MEDICINE INCcall | $0 | – | -50,000 | -100.0% | -0.14% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -32,666 | -100.0% | -0.16% | – |
| RLAY | Exit | RELAY THERAPEUTICS INCput | $0 | – | -80,000 | -100.0% | -0.18% | – |
| RLAY | Exit | RELAY THERAPEUTICS INCcall | $0 | – | -80,000 | -100.0% | -0.18% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -134,575 | -100.0% | -0.18% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INCcall | $0 | – | -300,000 | -100.0% | -0.20% | – |
| ARKG | Exit | ARK ETF TRgenomic rev etf | $0 | – | -40,961 | -100.0% | -0.22% | – |
| TCDA | Exit | TRICIDA INC | $0 | – | -670,771 | -100.0% | -0.22% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGnamen akt | $0 | – | -27,968 | -100.0% | -0.22% | – |
| VINC | Exit | VINCERX PHARMA INC | $0 | – | -199,057 | -100.0% | -0.23% | – |
| ISEE | Exit | IVERIC BIO INCcall | $0 | – | -200,000 | -100.0% | -0.23% | – |
| ALLK | Exit | ALLAKOS INC | $0 | – | -31,526 | -100.0% | -0.24% | – |
| Exit | TRILLIUM THERAPEUTICS INCcall | $0 | – | -198,400 | -100.0% | -0.24% | – | |
| XENE | Exit | XENON PHARMACEUTICALS INCput | $0 | – | -230,000 | -100.0% | -0.25% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS INCcall | $0 | – | -250,000 | -100.0% | -0.25% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INCput | $0 | – | -403,500 | -100.0% | -0.27% | – |
| AUPH | Exit | AURINIA PHARMACEUTICALS INCcall | $0 | – | -200,000 | -100.0% | -0.31% | – |
| OCUL | Exit | OCULAR THERAPEUTIX INCcall | $0 | – | -493,200 | -100.0% | -0.35% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INCcall | $0 | – | -600,000 | -100.0% | -0.37% | – |
| BCYC | Exit | BICYCLE THERAPEUTICS PLCcall | $0 | – | -130,000 | -100.0% | -0.38% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -196,400 | -100.0% | -0.41% | – |
| FATE | Exit | FATE THERAPEUTICS INCput | $0 | – | -100,000 | -100.0% | -0.42% | – |
| AZN | Exit | ASTRAZENECA PLCcall | $0 | – | -100,000 | -100.0% | -0.42% | – |
| ELAN | Exit | ELANCO ANIMAL HEALTH INCcall | $0 | – | -200,000 | -100.0% | -0.45% | – |
| IGMS | Exit | IGM BIOSCIENCES INCcall | $0 | – | -100,000 | -100.0% | -0.46% | – |
| INCY | Exit | INCYTE CORPcall | $0 | – | -98,700 | -100.0% | -0.48% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCsponsored ads | $0 | – | -229,202 | -100.0% | -0.48% | – |
| ITCI | Exit | INTRA-CELLULAR THERAPIES INC | $0 | – | -211,670 | -100.0% | -0.56% | – |
| XENE | Exit | XENON PHARMACEUTICALS INCcall | $0 | – | -546,700 | -100.0% | -0.59% | – |
| MGNX | Exit | MACROGENICS INCcall | $0 | – | -446,000 | -100.0% | -0.66% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INCcall | $0 | – | -493,600 | -100.0% | -0.70% | – |
| CCXI | Exit | CHEMOCENTRYX INCcall | $0 | – | -600,000 | -100.0% | -0.72% | – |
| CCXI | Exit | CHEMOCENTRYX INCput | $0 | – | -600,000 | -100.0% | -0.72% | – |
| EDIT | Exit | EDITAS MEDICINE INCput | $0 | – | -254,100 | -100.0% | -0.74% | – |
| MRK | Exit | MERCK & CO INCcall | $0 | – | -150,000 | -100.0% | -0.79% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INCput | $0 | – | -345,400 | -100.0% | -0.80% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -347,545 | -100.0% | -0.81% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCcall | $0 | – | -70,000 | -100.0% | -0.87% | – |
| CRTX | Exit | CORTEXYME INCcall | $0 | – | -142,100 | -100.0% | -0.92% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INCcall | $0 | – | -200,000 | -100.0% | -0.94% | – |
| NVAX | Exit | NOVAVAX INCcall | $0 | – | -70,000 | -100.0% | -1.02% | – |
| KRYS | Exit | KRYSTAL BIOTECH INCcall | $0 | – | -282,300 | -100.0% | -1.04% | – |
| KRYS | Exit | KRYSTAL BIOTECH INCput | $0 | – | -292,500 | -100.0% | -1.08% | – |
| RFL | Exit | RAFAEL HLDGS INCcall | $0 | – | -580,400 | -100.0% | -1.26% | – |
| CRSP | Exit | CRISPR THERAPEUTICS AGput | $0 | – | -197,300 | -100.0% | -1.56% | – |
| CMPS | Exit | COMPASS PATHWAYS PLCcall | $0 | – | -848,100 | -100.0% | -1.78% | – |
| UNH | Exit | UNITEDHEALTH GROUP INCcall | $0 | – | -100,000 | -100.0% | -2.75% | – |
| BIIB | Exit | BIOGEN INCcall | $0 | – | -167,500 | -100.0% | -3.34% | – |
| SPY | Exit | SPDR S&P 500 ETF TRput | $0 | – | -300,000 | -100.0% | -9.07% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| XENON PHARMACEUTICALS INC | 15 | Q2 2023 | 1.5% |
| OCULAR THERAPEUTIX INC | 15 | Q3 2023 | 1.4% |
| SAREPTA THERAPEUTICS INC | 14 | Q3 2023 | 6.4% |
| X4 PHARMACEUTICALS INC - PIPE | 14 | Q2 2023 | 1.4% |
| PROTARA THERAPEUTICS INC | 14 | Q3 2023 | 1.2% |
| SPDR SER TR | 13 | Q3 2023 | 9.0% |
| VAXCYTE INC | 13 | Q3 2023 | 2.9% |
| TRACON PHARMACEUTICALS INC | 13 | Q3 2023 | 1.4% |
| MILESTONE PHARMACEUTICALS IN | 13 | Q3 2023 | 1.7% |
| BELLUS HEALTH INC NEW | 13 | Q1 2023 | 1.8% |
View Ikarian Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Milestone Pharmaceuticals Inc. | February 14, 2023 | 460,416 | 1.3% |
| X4 Pharmaceuticals, Inc | February 14, 2023 | 349,133 | 0.3% |
| aTYR PHARMA INC | February 14, 2022 | 35,048 | 0.1% |
| Cyclacel Pharmaceuticals, Inc. | February 14, 2022 | 99,422 | 1.0% |
| KalVista Pharmaceuticals, Inc. | February 14, 2022 | 36,576 | 0.2% |
| Lyra Therapeutics, Inc. | February 14, 2022 | 394,536 | 3.0% |
| Odonate Therapeutics, Inc. | February 14, 2022 | 1,340,631 | 3.5% |
| Protara Therapeutics, Inc. | February 14, 2022 | 279,256 | 2.5% |
| Science 37 Holdings, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
| scPharmaceuticals Inc. | February 14, 2022 | 901,362 | 3.3% |
View Ikarian Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-05 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
View Ikarian Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.