| Samsara BioCapital, LLC | 2,780,261 | $10,870,821 | 3.33% |
|---|
| Perceptive Advisors | 12,757,562 | $49,882,067 | 1.66% |
|---|
| Nantahala Capital Management | 4,050,218 | $15,836,352 | 1.35% |
|---|
| PURA VIDA INVESTMENTS, LLC | 1,413,242 | $5,525,776 | 1.04% |
|---|
| Ikarian Capital, LLC | 1,254,384 | $4,904,641 | 0.59% |
|---|
| Parkman Healthcare Partners LLC | 625,056 | $2,443,969 | 0.45% |
|---|
| VR Adviser, LLC | 924,170 | $3,613,505 | 0.38% |
|---|
| Soleus Capital Management, L.P. | 592,417 | $2,316,350 | 0.21% |
|---|
| ARMISTICE CAPITAL, LLC | 1,550,000 | $6,060,500 | 0.09% |
|---|
| Clearline Capital LP | 119,128 | $465,790 | 0.04% |
|---|
| PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 30,000 | $117,000 | 0.03% |
|---|
| BOOTHBAY FUND MANAGEMENT, LLC | 234,003 | $914,952 | 0.02% |
|---|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 141,800 | $554,438 | 0.01% |
|---|
| Virtu Financial LLC | 19,618 | $77 | 0.01% |
|---|
| Alyeska Investment Group, L.P. | 240,723 | $941,227 | 0.01% |
|---|
| Ensign Peak Advisors, Inc | 301,533 | $1,178,994 | 0.00% |
|---|
| Alyeska Investment Group, L.P. | 130,839 | $511,580 | 0.00% |
|---|
| LETKO, BROSSEAU & ASSOCIATES INC | 31,900 | $124,729 | 0.00% |
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| Ameliora Wealth Management Ltd. | 750 | $2,925 | 0.00% |
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| Citadel Advisors | 2,848,564 | $11,137,885 | 0.00% |
|---|