$1.33 Billion is the total value of Ikarian Capital, LLC's 151 reported holdings in Q1 2020. The portfolio turnover from Q4 2019 to Q1 2020 was 218.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SPY | New | SPDR S&P 500 ETF TRput | $244,863,000 | – | 950,000 | +100.0% | 18.42% | – |
| TLT | New | ISHARES TRput | $65,988,000 | – | 400,000 | +100.0% | 4.96% | – |
| SPY | New | SPDR S&P 500 ETF TRcall | $64,438,000 | – | 250,000 | +100.0% | 4.85% | – |
| REGN | New | REGENERON PHARMACEUTICALSput | $63,478,000 | – | 130,000 | +100.0% | 4.77% | – |
| BIIB | New | BIOGEN INCcall | $45,369,000 | – | 143,400 | +100.0% | 3.41% | – |
| QQQ | New | INVESCO QQQ TRput | $29,552,000 | – | 550,000 | +100.0% | 2.22% | – |
| XLRN | New | ACCELERON PHARMA INCput | $28,480,000 | – | 316,900 | +100.0% | 2.14% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCcall | $26,875,000 | – | 246,900 | +100.0% | 2.02% | – |
| AXSM | New | AXSOME THERAPEUTICS INCcall | $22,061,000 | – | 375,000 | +100.0% | 1.66% | – |
| XLRN | New | ACCELERON PHARMA INC | $21,501,000 | – | 239,249 | +100.0% | 1.62% | – |
| MYOK | Buy | MYOKARDIA INCput | $19,671,000 | +357.5% | 419,600 | +611.2% | 1.48% | +112.2% |
| XBI | New | SPDR SER TRcall | $19,360,000 | – | 250,000 | +100.0% | 1.46% | – |
| XLRN | New | ACCELERON PHARMA INCcall | $18,891,000 | – | 210,200 | +100.0% | 1.42% | – |
| ZGNX | Buy | ZOGENIX INCput | $18,533,000 | +139.9% | 749,400 | +405.7% | 1.39% | +11.3% |
| RETA | New | REATA PHARMACEUTICALS INCput | $18,043,000 | – | 125,000 | +100.0% | 1.36% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INCcall | $17,958,000 | – | 200,000 | +100.0% | 1.35% | – |
| IWM | New | ISHARES TRput | $17,169,000 | – | 150,000 | +100.0% | 1.29% | – |
| ARGX | New | ARGENX SEput | $16,572,000 | – | 125,800 | +100.0% | 1.25% | – |
| BTAI | Buy | BIOXCEL THERAPEUTICS INC | $15,505,000 | +570.1% | 693,716 | +338.0% | 1.17% | +210.9% |
| LGND | New | LIGAND PHARMACEUTICALS INCcall | $14,544,000 | – | 200,000 | +100.0% | 1.09% | – |
| VSTM | New | VERASTEM INC | $13,866,000 | – | 5,252,427 | +100.0% | 1.04% | – |
| ZGNX | New | ZOGENIX INC | $13,588,000 | – | 549,459 | +100.0% | 1.02% | – |
| IMVT | Buy | IMMUNOVANT INC | $13,113,000 | +63.9% | 842,463 | +67.1% | 0.99% | -23.9% |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCput | $13,095,000 | – | 120,300 | +100.0% | 0.98% | – |
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO Lcall | $11,911,000 | +9.4% | 350,000 | +75.0% | 0.90% | -49.2% |
| MRTX | Buy | MIRATI THERAPEUTICS INCput | $11,446,000 | +81.7% | 148,900 | +204.5% | 0.86% | -15.7% |
| ABBV | New | ABBVIE INCcall | $11,429,000 | – | 150,000 | +100.0% | 0.86% | – |
| KPTI | Buy | KARYOPHARM THERAPEUTICS INCput | $10,600,000 | +176.3% | 551,800 | +175.8% | 0.80% | +28.1% |
| TARA | New | ARTARA THERAPEUTICS INC | $10,368,000 | – | 450,772 | +100.0% | 0.78% | – |
| ACAD | Buy | ACADIA PHARMACEUTICALS INCput | $10,140,000 | +69.3% | 240,000 | +71.4% | 0.76% | -21.3% |
| ADRO | Buy | ADURO BIOTECH INC | $9,968,000 | +359.6% | 3,638,000 | +97.9% | 0.75% | +113.7% |
| ARGX | New | ARGENX SEcall | $9,880,000 | – | 75,000 | +100.0% | 0.74% | – |
| AXSM | Buy | AXSOME THERAPEUTICS INCput | $8,825,000 | +206.0% | 150,000 | +437.6% | 0.66% | +42.2% |
| ARGX | New | ARGENX SEsponsored adr | $8,675,000 | – | 65,856 | +100.0% | 0.65% | – |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INCcall | $8,655,000 | +1018.2% | 100,000 | +1288.9% | 0.65% | +420.8% |
| ARDX | Buy | ARDELYX INC | $8,313,000 | +71.6% | 1,462,234 | +126.5% | 0.62% | -20.4% |
| SCPH | New | SCPHARMACEUTICALS INC | $7,945,000 | – | 1,073,647 | +100.0% | 0.60% | – |
| OCUL | Buy | OCULAR THERAPEUTIX INC | $7,717,000 | +250.3% | 1,558,936 | +179.6% | 0.58% | +62.5% |
| CRSP | Buy | CRISPR THERAPEUTICS AGput | $7,596,000 | +0.8% | 179,100 | +44.8% | 0.57% | -53.2% |
| CHMA | Buy | CHIASMA INC | $7,576,000 | +38.5% | 2,075,492 | +88.1% | 0.57% | -35.7% |
| KURA | New | KURA ONCOLOGY INC | $7,560,000 | – | 759,803 | +100.0% | 0.57% | – |
| MLND | New | MILLENDO THERAPEUTICS INCput | $7,413,000 | – | 1,403,900 | +100.0% | 0.56% | – |
| CARA | New | CARA THERAPEUTICS INC | $7,294,000 | – | 552,163 | +100.0% | 0.55% | – |
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $7,242,000 | +91.4% | 946,605 | +345.6% | 0.54% | -11.1% |
| FGEN | New | FIBROGEN INCcall | $6,950,000 | – | 200,000 | +100.0% | 0.52% | – |
| GLPG | New | GALAPAGOS NVcall | $6,857,000 | – | 35,000 | +100.0% | 0.52% | – |
| SBBP | New | STRONGBRIDGE BIOPHARMA PLC | $6,412,000 | – | 3,392,787 | +100.0% | 0.48% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INCcall | $6,338,000 | – | 150,000 | +100.0% | 0.48% | – |
| CCXI | New | CHEMOCENTRYX INCcall | $6,027,000 | – | 150,000 | +100.0% | 0.45% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCcall | $5,955,000 | – | 750,000 | +100.0% | 0.45% | – |
| CYTK | New | CYTOKINETICS INCcall | $5,895,000 | – | 500,000 | +100.0% | 0.44% | – |
| CVM | Buy | CEL SCI CORPput | $5,770,000 | +110.0% | 500,000 | +66.6% | 0.43% | -2.5% |
| KNSA | New | KINIKSA PHARMACEUTICALS LTD | $5,556,000 | – | 358,924 | +100.0% | 0.42% | – |
| KDMN | New | KADMON HLDGS INC | $5,518,000 | – | 1,316,846 | +100.0% | 0.42% | – |
| MYOK | New | MYOKARDIA INCcall | $5,316,000 | – | 113,400 | +100.0% | 0.40% | – |
| ZGNX | Buy | ZOGENIX INCcall | $5,265,000 | +2093.8% | 212,900 | +4528.3% | 0.40% | +915.4% |
| SAGE | Buy | SAGE THERAPEUTICS INC | $5,257,000 | -45.2% | 183,051 | +37.6% | 0.40% | -74.6% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $5,030,000 | +57.6% | 443,582 | +82.2% | 0.38% | -26.9% |
| CLVS | Buy | CLOVIS ONCOLOGY INCcall | $4,928,000 | -8.0% | 774,900 | +50.8% | 0.37% | -57.3% |
| INSM | Buy | INSMED INCcall | $4,809,000 | +229.2% | 300,000 | +390.2% | 0.36% | +52.7% |
| CYTK | New | CYTOKINETICS INCput | $4,532,000 | – | 384,400 | +100.0% | 0.34% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL INcall | $4,443,000 | – | 100,000 | +100.0% | 0.33% | – |
| SAGE | New | SAGE THERAPEUTICS INCcall | $4,431,000 | – | 154,300 | +100.0% | 0.33% | – |
| TCDA | New | TRICIDA INC | $3,956,000 | – | 179,800 | +100.0% | 0.30% | – |
| BPMC | New | BLUEPRINT MEDICINES CORPput | $3,860,000 | – | 66,000 | +100.0% | 0.29% | – |
| ITCI | New | INTRA CELLULAR THERAPIES INC | $3,827,000 | – | 249,002 | +100.0% | 0.29% | – |
| ASND | New | ASCENDIS PHARMA A Sput | $3,761,000 | – | 70,000 | +100.0% | 0.28% | – |
| BMYRT | New | BRISTOL-MYERS SQUIBB COright 99/99/9999 | $3,610,000 | – | 950,000 | +100.0% | 0.27% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $3,503,000 | – | 2,366,850 | +100.0% | 0.26% | – |
| MYOV | New | MYOVANT SCIENCES LTD | $3,398,000 | – | 450,000 | +100.0% | 0.26% | – |
| BLUE | New | BLUEBIRD BIO INCcall | $3,217,000 | – | 70,000 | +100.0% | 0.24% | – |
| BPMC | New | BLUEPRINT MEDICINES CORPcall | $2,924,000 | – | 50,000 | +100.0% | 0.22% | – |
| FGEN | New | FIBROGEN INCput | $2,780,000 | – | 80,000 | +100.0% | 0.21% | – |
| INSM | New | INSMED INC | $2,772,000 | – | 172,919 | +100.0% | 0.21% | – |
| OTIC | Buy | OTONOMY INC | $2,694,000 | -34.1% | 1,367,271 | +28.1% | 0.20% | -69.3% |
| CLVS | New | CLOVIS ONCOLOGY INC | $2,620,000 | – | 411,918 | +100.0% | 0.20% | – |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $2,622,000 | +250.1% | 1,680,529 | +380.2% | 0.20% | +62.8% |
| BBIO | New | BRIDGEBIO PHARMA INC | $2,549,000 | – | 87,900 | +100.0% | 0.19% | – |
| BTAI | New | BIOXCEL THERAPEUTICS INCcall | $2,309,000 | – | 103,300 | +100.0% | 0.17% | – |
| ARVN | Buy | ARVINAS INCcall | $2,261,000 | +1680.3% | 56,100 | +1709.7% | 0.17% | +709.5% |
| NTLA | New | INTELLIA THERAPEUTICS INC | $2,262,000 | – | 184,989 | +100.0% | 0.17% | – |
| CASI | New | CASI PHARMACEUTICALS INC | $2,121,000 | – | 1,039,910 | +100.0% | 0.16% | – |
| MGNX | Buy | MACROGENICS INC | $2,095,000 | +1822.0% | 360,030 | +3489.5% | 0.16% | +777.8% |
| NERV | Buy | MINERVA NEUROSCIENCES INCcall | $2,056,000 | +287.9% | 341,600 | +358.5% | 0.16% | +80.2% |
| RLMD | New | RELMADA THERAPEUTICS INC | $1,882,000 | – | 55,172 | +100.0% | 0.14% | – |
| INO | New | INOVIO PHARMACEUTICALS INCput | $1,860,000 | – | 250,000 | +100.0% | 0.14% | – |
| ADMA | New | ADMA BIOLOGICS INC | $1,814,000 | – | 630,000 | +100.0% | 0.14% | – |
| AGTC | Buy | APPLIED GENETIC TECHNOL CORP | $1,790,000 | +97.1% | 545,884 | +171.7% | 0.14% | -8.2% |
| IWM | New | ISHARES TRrussell 2000 etf | $1,735,000 | – | 15,154 | +100.0% | 0.13% | – |
| NERV | New | MINERVA NEUROSCIENCES INCput | $1,678,000 | – | 278,700 | +100.0% | 0.13% | – |
| ALBO | New | ALBIREO PHARMA INCcall | $1,645,000 | – | 100,500 | +100.0% | 0.12% | – |
| NXTC | New | NEXTCURE INCput | $1,509,000 | – | 40,700 | +100.0% | 0.11% | – |
| AUPH | New | AURINIA PHARMACEUTICALS INCput | $1,451,000 | – | 100,000 | +100.0% | 0.11% | – |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $1,396,000 | +69700.0% | 52,126 | +98250.9% | 0.10% | – |
| CERC | Buy | CERECOR INC | $1,399,000 | -50.1% | 564,005 | +8.5% | 0.10% | -76.9% |
| ALLK | New | ALLAKOS INCput | $1,335,000 | – | 30,000 | +100.0% | 0.10% | – |
| SLDB | New | SOLID BIOSCIENCES INC | $1,288,000 | – | 539,053 | +100.0% | 0.10% | – |
| APTX | New | APTINYX INC | $1,277,000 | – | 591,000 | +100.0% | 0.10% | – |
| SAVA | New | CASSAVA SCIENCES INC | $1,233,000 | – | 300,000 | +100.0% | 0.09% | – |
| CRTX | New | CORTEXYME INC | $1,140,000 | – | 25,000 | +100.0% | 0.09% | – |
| OVID | Buy | OVID THERAPEUTICS INC | $1,126,000 | -22.5% | 377,737 | +7.9% | 0.08% | -63.8% |
| PTGX | Buy | PROTAGONIST THERAPEUTICS INC | $1,117,000 | +102.4% | 158,222 | +102.0% | 0.08% | -5.6% |
| FATE | New | FATE THERAPEUTICS INCput | $1,113,000 | – | 50,100 | +100.0% | 0.08% | – |
| FATE | New | FATE THERAPEUTICS INCcall | $1,113,000 | – | 50,100 | +100.0% | 0.08% | – |
| SLDB | Buy | SOLID BIOSCIENCES INCcall | $1,075,000 | -21.0% | 449,800 | +47.2% | 0.08% | -63.2% |
| MBIO | Buy | MUSTANG BIO INC | $955,000 | -27.6% | 356,475 | +10.3% | 0.07% | -66.4% |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $894,000 | +12.0% | 228,113 | +206.0% | 0.07% | -48.1% |
| ICAD | New | ICAD INC | $786,000 | – | 107,103 | +100.0% | 0.06% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $700,000 | – | 36,422 | +100.0% | 0.05% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCsponsored adr | $652,000 | – | 82,143 | +100.0% | 0.05% | – |
| NERV | Buy | MINERVA NEUROSCIENCES INC | $623,000 | -12.4% | 103,504 | +3.5% | 0.05% | -59.1% |
| OTIC | New | OTONOMY INCcall | $591,000 | – | 300,000 | +100.0% | 0.04% | – |
| PFNX | New | PFENEX INC | $566,000 | – | 64,211 | +100.0% | 0.04% | – |
| KOD | New | KODIAK SCIENCES INCput | $563,000 | – | 11,800 | +100.0% | 0.04% | – |
| BXRX | New | BAUDAX BIO INC | $434,000 | – | 175,000 | +100.0% | 0.03% | – |
| CMRX | Buy | CHIMERIX INC | $300,000 | -14.5% | 208,258 | +20.4% | 0.02% | -59.6% |
| BLUE | New | BLUEBIRD BIO INC | $299,000 | – | 6,498 | +100.0% | 0.02% | – |
| CLLS | New | CELLECTIS S Asponsored ads | $285,000 | – | 30,928 | +100.0% | 0.02% | – |
| BIIB | New | BIOGEN INC | $252,000 | – | 795 | +100.0% | 0.02% | – |
| CARA | Buy | CARA THERAPEUTICS INCcall | $259,000 | -9.1% | 19,600 | +10.7% | 0.02% | -58.7% |
| DBVT | New | DBV TECHNOLOGIES S Aput | $207,000 | – | 52,800 | +100.0% | 0.02% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2020-05-15
Signatures
The EDGAR filing(s) were signed by:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| XENON PHARMACEUTICALS INC | 15 | Q2 2023 | 1.5% |
| OCULAR THERAPEUTIX INC | 15 | Q3 2023 | 1.4% |
| SAREPTA THERAPEUTICS INC | 14 | Q3 2023 | 6.4% |
| X4 PHARMACEUTICALS INC - PIPE | 14 | Q2 2023 | 1.4% |
| PROTARA THERAPEUTICS INC | 14 | Q3 2023 | 1.2% |
| SPDR SER TR | 13 | Q3 2023 | 9.0% |
| VAXCYTE INC | 13 | Q3 2023 | 2.9% |
| TRACON PHARMACEUTICALS INC | 13 | Q3 2023 | 1.4% |
| MILESTONE PHARMACEUTICALS IN | 13 | Q3 2023 | 1.7% |
| BELLUS HEALTH INC NEW | 13 | Q1 2023 | 1.8% |
View Ikarian Capital, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Milestone Pharmaceuticals Inc. | February 14, 2023 | 460,416 | 1.3% |
| X4 Pharmaceuticals, Inc | February 14, 2023 | 349,133 | 0.3% |
| aTYR PHARMA INC | February 14, 2022 | 35,048 | 0.1% |
| Cyclacel Pharmaceuticals, Inc. | February 14, 2022 | 99,422 | 1.0% |
| KalVista Pharmaceuticals, Inc. | February 14, 2022 | 36,576 | 0.2% |
| Lyra Therapeutics, Inc. | February 14, 2022 | 394,536 | 3.0% |
| Odonate Therapeutics, Inc. | February 14, 2022 | 1,340,631 | 3.5% |
| Protara Therapeutics, Inc. | February 14, 2022 | 279,256 | 2.5% |
| Science 37 Holdings, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
| scPharmaceuticals Inc. | February 14, 2022 | 901,362 | 3.3% |
View Ikarian Capital, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-05 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
| SC 13G/A | 2023-02-14 |
View Ikarian Capital, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.