Integral Health Asset Management, LLC Activity Q4 2019-Q3 2023

Q3 2023

			Value		Shares		↓ Weighting
THC	Buy	TENET HEALTHCARE CORP	$35,580,600	+88.5%	540,000	+132.8%	4.93%	+110.7%
ARGX	Buy	ARGENX SEsponsored adr	$34,414,100	+120.8%	70,000	+75.0%	4.76%	+146.8%
BSX	Buy	BOSTON SCIENTIFIC CORP	$29,040,000	+15.2%	550,000	+18.0%	4.02%	+28.8%
	Buy	MOONLAKE IMMUNOTHERAPEUTICSclass a ord	$28,500,000	+86.3%	500,000	+66.7%	3.95%	+108.3%
CYTK	Buy	CYTOKINETICS INC	$23,568,000	+11.2%	800,000	+23.1%	3.26%	+24.3%
MDT	Buy	MEDTRONIC PLC	$23,508,000	+233.5%	300,000	+275.0%	3.25%	+272.7%
NARI	Buy	INARI MED INC	$22,890,000	+154.0%	350,000	+125.8%	3.17%	+184.0%
MCK	Sell	MCKESSON CORP	$21,742,500	-29.3%	50,000	-30.6%	3.01%	-21.0%
INSP	Buy	INSPIRE MED SYS INC	$20,836,200	-37.7%	105,000	+1.9%	2.88%	-30.3%
NVS	Buy	NOVARTIS AGsponsored adr	$20,372,000	+96.0%	200,000	+94.2%	2.82%	+119.1%
ABC	Buy	CENCORA INC	$19,796,700	+295.7%	110,000	+323.1%	2.74%	+342.1%
AMGN	New	AMGEN INC	$17,469,400	–	65,000	–	2.42%	–
CI	Sell	THE CIGNA GROUP	$17,164,200	-66.0%	60,000	-66.7%	2.38%	-62.0%
BDX	New	BECTON DICKINSON & CO	$16,804,450	–	65,000	–	2.33%	–
EHC	Buy	ENCOMPASS HEALTH CORP	$16,790,000	+12.7%	250,000	+13.6%	2.32%	+26.0%
DXCM	New	DEXCOM INC	$16,327,500	–	175,000	–	2.26%	–
	Buy	VENTYX BIOSCIENCES INC	$14,933,900	+30.1%	430,000	+22.9%	2.07%	+45.5%
RVMD	Buy	REVOLUTION MEDICINES INC	$14,532,000	+52.6%	525,000	+47.5%	2.01%	+70.7%
LLY	Sell	ELI LILLY & CO	$13,428,250	-4.6%	25,000	-16.7%	1.86%	+6.7%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$12,482,250	+122.3%	275,000	+175.0%	1.73%	+148.6%
MOH	New	MOLINA HEALTHCARE INC	$11,476,150	–	35,000	–	1.59%	–
TDOC	Buy	TELADOC HEALTH INC	$11,154,000	+120.3%	600,000	+200.0%	1.54%	+146.3%
PKI	Sell	REVVITY INC	$11,070,000	-33.4%	100,000	-28.6%	1.53%	-25.5%
AVTR	New	AVANTOR INC	$11,067,000	–	525,000	–	1.53%	–
ANTM	Sell	ELEVANCE HEALTH INC	$10,885,500	-18.3%	25,000	-16.7%	1.51%	-8.7%
SIBN	Buy	SI-BONE INC	$10,301,400	+68.2%	485,000	+113.7%	1.43%	+88.1%
GH	Sell	GUARDANT HEALTH INC	$9,633,000	-34.7%	325,000	-21.1%	1.33%	-26.9%
NBIX	New	NEUROCRINE BIOSCIENCES INC	$9,562,500	–	85,000	–	1.32%	–
LFST	Buy	LIFESTANCE HEALTH GROUP INC	$8,931,000	+26.5%	1,300,000	+68.2%	1.24%	+41.4%
VKTX	Buy	VIKING THERAPEUTICS INC	$8,856,000	-25.2%	800,000	+9.6%	1.23%	-16.3%
NTRA	New	NATERA INC	$8,850,000	–	200,000	–	1.22%	–
HOLX	Sell	HOLOGIC INC	$8,675,000	-38.8%	125,000	-28.6%	1.20%	-31.6%
	New	MOONLAKE IMMUNOTHERAPEUTICSput	$8,550,000	–	150,000	–	1.18%	–
ELAN	Buy	ELANCO ANIMAL HEALTH INC	$8,407,520	+317.9%	748,000	+274.0%	1.16%	+367.5%
KRYS	Buy	KRYSTAL BIOTECH INC	$8,120,000	+11.6%	70,000	+12.9%	1.12%	+24.8%
ZBH	Sell	ZIMMER BIOMET HOLDINGS INC	$7,855,400	-82.0%	70,000	-76.7%	1.09%	-79.9%
ALKS	Sell	ALKERMES PLC	$7,702,750	-13.3%	275,000	-3.2%	1.07%	-3.2%
CTLT	New	CATALENT INC	$7,284,800	–	160,000	–	1.01%	–
BBIO	New	BRIDGEBIO PHARMA INC	$7,251,750	–	275,000	–	1.00%	–
ITCI	Sell	INTRA-CELLULAR THERAPIES INC	$6,927,970	-22.9%	133,000	-6.3%	0.96%	-13.8%
RLAY	Buy	RELAY THERAPEUTICS INC	$6,728,000	-23.5%	800,000	+14.3%	0.93%	-14.5%
PACB	New	PACIFIC BIOSCIENCES CALIF IN	$6,680,000	–	800,000	–	0.92%	–
SUPN	Buy	SUPERNUS PHARMACEUTICALS INC	$6,065,400	+169.0%	220,000	+193.3%	0.84%	+201.1%
	New	SAREPTA THERAPEUTICS INCcall	$6,061,000	–	50,000	–	0.84%	–
CRNX	New	CRINETICS PHARMACEUTICALS IN	$5,948,000	–	200,000	–	0.82%	–
WBA	New	WALGREENS BOOTS ALLIANCE INC	$5,560,000	–	250,000	–	0.77%	–
	New	ROIVANT SCIENCES LTD	$5,256,000	–	450,000	–	0.73%	–
MRK	New	MERCK & CO INC	$5,147,500	–	50,000	–	0.71%	–
AKRO	Buy	AKERO THERAPEUTICS INC	$5,058,000	+54.8%	100,000	+42.9%	0.70%	+72.8%
CABA	New	CABALETTA BIO INC	$5,022,600	–	330,000	–	0.70%	–
PFE	New	PFIZER INC	$4,975,500	–	150,000	–	0.69%	–
COO	Sell	COOPER COS INC	$4,770,150	-76.1%	15,000	-71.2%	0.66%	-73.3%
REPL	Sell	REPLIMUNE GROUP INC	$4,277,500	-58.6%	250,000	-43.8%	0.59%	-53.7%
LBPH	Buy	LONGBOARD PHARMACEUTICALS IN	$4,225,600	-3.7%	760,000	+27.1%	0.58%	+7.7%
ZTS	New	ZOETIS INCcl a	$3,479,600	–	20,000	–	0.48%	–
	New	89BIO INCcall	$3,088,000	–	200,000	–	0.43%	–
WW	New	WW INTL INC	$2,767,500	–	250,000	–	0.38%	–
TNDM	New	TANDEM DIABETES CARE INC	$2,700,100	–	130,000	–	0.37%	–
BPMC	New	BLUEPRINT MEDICINES CORP	$2,511,000	–	50,000	–	0.35%	–
HCA	Sell	HCA HEALTHCARE INC	$2,459,800	-79.7%	10,000	-75.0%	0.34%	-77.3%
SILK	New	SILK RD MED INC	$2,248,500	–	150,000	–	0.31%	–
RVNC	Sell	REVANCE THERAPEUTICS INC	$1,147,000	-81.9%	100,000	-60.0%	0.16%	-79.7%
DYN	Exit	DYNE THERAPEUTICS INC	$0	–	-62,000	–	-0.09%	–
TERN	Exit	TERNS PHARMACEUTICALS INC	$0	–	-180,000	–	-0.20%	–
ALLO	Exit	ALLOGENE THERAPEUTICS INC	$0	–	-412,000	–	-0.25%	–
PTGX	Exit	PROTAGONIST THERAPEUTICS INC	$0	–	-75,000	–	-0.26%	–
KROS	Exit	KEROS THERAPEUTICS INC	$0	–	-52,000	–	-0.26%	–
	Exit	UNIQURE NVcall	$0	–	-200,000	–	-0.28%	–
	Exit	WALGREENS BOOTS ALLIANCE INCcall	$0	–	-100,000	–	-0.35%	–
PRTA	Exit	PROTHENA CORP PLC	$0	–	-52,000	–	-0.44%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-80,000	–	-0.47%	–
BNTX	Exit	BIONTECH SEsponsored ads	$0	–	-36,000	–	-0.48%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-100,000	–	-0.50%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-50,000	–	-0.54%	–
CCRN	Exit	CROSS CTRY HEALTHCARE INC	$0	–	-155,000	–	-0.54%	–
FOLD	Exit	AMICUS THERAPEUTICS INC	$0	–	-387,000	–	-0.60%	–
PRVA	Exit	PRIVIA HEALTH GROUP INC	$0	–	-200,000	–	-0.65%	–
TGTX	Exit	TG THERAPEUTICS INC	$0	–	-250,000	–	-0.77%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-72,000	–	-0.81%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-174,000	–	-0.88%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-88,000	–	-1.02%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-206,000	–	-1.04%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-52,000	–	-1.22%	–
PEN	Exit	PENUMBRA INC	$0	–	-30,000	–	-1.28%	–
SGRY	Exit	SURGERY PARTNERS INC	$0	–	-250,000	–	-1.39%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-72,000	–	-1.48%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-50,000	–	-1.49%	–
RETA	Exit	REATA PHARMACEUTICALS INCcl a	$0	–	-120,000	–	-1.52%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-36,000	–	-1.52%	–
	Exit	GSK PLCsponsored adr	$0	–	-350,000	–	-1.54%	–
SDGR	Exit	SCHRODINGER INC	$0	–	-265,000	–	-1.64%	–
ABBV	Exit	ABBVIE INC	$0	–	-100,000	–	-1.67%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-200,000	–	-1.67%	–
	Exit	NOVO-NORDISK A Sput	$0	–	-250,000	–	-5.01%	–

Q2 2023

			Value		Shares		↓ Weighting
CI	New	THE CIGNA GROUP	$50,508,000	–	180,000	–	6.25%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$43,680,000	–	300,000	–	5.41%	–
	New	NOVO-NORDISK A Sput	$40,457,500	–	250,000	–	5.01%	–
INSP	New	INSPIRE MED SYS INC	$33,437,920	–	103,000	–	4.14%	–
MCK	New	MCKESSON CORP	$30,766,320	–	72,000	–	3.81%	–
BSX	New	BOSTON SCIENTIFIC CORP	$25,205,940	–	466,000	–	3.12%	–
CYTK	New	CYTOKINETICS INC	$21,203,000	–	650,000	–	2.62%	–
COO	New	COOPER COS INC	$19,938,360	–	52,000	–	2.47%	–
THC	New	TENET HEALTHCARE CORP	$18,880,160	–	232,000	–	2.34%	–
PKI	New	REVVITY INC	$16,630,600	–	140,000	–	2.06%	–
ARGX	New	ARGENX SEsponsored adr	$15,589,200	–	40,000	–	1.93%	–
	New	MOONLAKE IMMUNOTHERAPEUTICSclass a ord	$15,300,000	–	300,000	–	1.89%	–
EHC	New	ENCOMPASS HEALTH CORP	$14,896,200	–	220,000	–	1.84%	–
GH	New	GUARDANT HEALTH INC	$14,749,600	–	412,000	–	1.83%	–
HOLX	New	HOLOGIC INC	$14,169,750	–	175,000	–	1.76%	–
LLY	New	LILLY ELI & CO	$14,069,400	–	30,000	–	1.74%	–
CNC	New	CENTENE CORP DEL	$13,490,000	–	200,000	–	1.67%	–
ABBV	New	ABBVIE INC	$13,473,000	–	100,000	–	1.67%	–
ANTM	New	ELEVANCE HEALTH INC	$13,328,700	–	30,000	–	1.65%	–
SDGR	New	SCHRODINGER INC	$13,228,800	–	265,000	–	1.64%	–
ZNTL	New	ZENTALIS PHARMACEUTICALS INC	$12,694,500	–	450,000	–	1.57%	–
	New	GSK PLCsponsored adr	$12,474,000	–	350,000	–	1.54%	–
ISRG	New	INTUITIVE SURGICAL INC	$12,309,840	–	36,000	–	1.52%	–
RETA	New	REATA PHARMACEUTICALS INCcl a	$12,235,200	–	120,000	–	1.52%	–
HCA	New	HCA HEALTHCARE INC	$12,139,200	–	40,000	–	1.50%	–
DHR	New	DANAHER CORPORATION	$12,000,000	–	50,000	–	1.49%	–
JNJ	New	JOHNSON & JOHNSON	$11,917,440	–	72,000	–	1.48%	–
VKTX	New	VIKING THERAPEUTICS INC	$11,833,300	–	730,000	–	1.46%	–
	New	VENTYX BIOSCIENCES INC	$11,480,000	–	350,000	–	1.42%	–
SGRY	New	SURGERY PARTNERS INC	$11,247,500	–	250,000	–	1.39%	–
NVS	New	NOVARTIS AGsponsored adr	$10,393,730	–	103,000	–	1.29%	–
REPL	New	REPLIMUNE GROUP INC	$10,332,900	–	445,000	–	1.28%	–
PEN	New	PENUMBRA INC	$10,321,800	–	30,000	–	1.28%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$9,876,880	–	52,000	–	1.22%	–
RVMD	New	REVOLUTION MEDICINES INC	$9,523,000	–	356,000	–	1.18%	–
NARI	New	INARI MED INC	$9,011,700	–	155,000	–	1.12%	–
ITCI	New	INTRA-CELLULAR THERAPIES INC	$8,991,440	–	142,000	–	1.11%	–
ALKS	New	ALKERMES PLC	$8,889,200	–	284,000	–	1.10%	–
RLAY	New	RELAY THERAPEUTICS INC	$8,792,000	–	700,000	–	1.09%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$8,400,680	–	206,000	–	1.04%	–
EXAS	New	EXACT SCIENCES CORP	$8,263,200	–	88,000	–	1.02%	–
TEVA	New	TEVA PHARMACEUTICAL INDS LTDsponsored ads	$7,530,000	–	1,000,000	–	0.93%	–
KRYS	New	KRYSTAL BIOTECH INC	$7,278,800	–	62,000	–	0.90%	–
PTCT	New	PTC THERAPEUTICS INC	$7,076,580	–	174,000	–	0.88%	–
LFST	New	LIFESTANCE HEALTH GROUP INC	$7,057,490	–	773,000	–	0.87%	–
MDT	New	MEDTRONIC PLC	$7,048,000	–	80,000	–	0.87%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$6,559,200	–	72,000	–	0.81%	–
RVNC	New	REVANCE THERAPEUTICS INC	$6,327,500	–	250,000	–	0.78%	–
TGTX	New	TG THERAPEUTICS INC	$6,210,000	–	250,000	–	0.77%	–
SIBN	New	SI-BONE INC	$6,124,460	–	227,000	–	0.76%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$5,614,000	–	100,000	–	0.70%	–
PRVA	New	PRIVIA HEALTH GROUP INC	$5,222,000	–	200,000	–	0.65%	–
NVST	New	ENVISTA HOLDINGS CORPORATION	$5,076,000	–	150,000	–	0.63%	–
TDOC	New	TELADOC HEALTH INC	$5,064,000	–	200,000	–	0.63%	–
ABC	New	AMERISOURCEBERGEN CORP	$5,003,180	–	26,000	–	0.62%	–
FOLD	New	AMICUS THERAPEUTICS INC	$4,860,720	–	387,000	–	0.60%	–
LBPH	New	LONGBOARD PHARMACEUTICALS IN	$4,389,320	–	598,000	–	0.54%	–
CCRN	New	CROSS CTRY HEALTHCARE INC	$4,352,400	–	155,000	–	0.54%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$4,334,000	–	50,000	–	0.54%	–
XRAY	New	DENTSPLY SIRONA INC	$4,002,000	–	100,000	–	0.50%	–
BNTX	New	BIONTECH SEsponsored ads	$3,885,480	–	36,000	–	0.48%	–
SAGE	New	SAGE THERAPEUTICS INC	$3,761,600	–	80,000	–	0.47%	–
PRTA	New	PROTHENA CORP PLC	$3,550,560	–	52,000	–	0.44%	–
AKRO	New	AKERO THERAPEUTICS INC	$3,268,300	–	70,000	–	0.40%	–
	New	WALGREENS BOOTS ALLIANCE INCcall	$2,849,000	–	100,000	–	0.35%	–
	New	UNIQURE NVcall	$2,292,000	–	200,000	–	0.28%	–
SUPN	New	SUPERNUS PHARMACEUTICALS INC	$2,254,500	–	75,000	–	0.28%	–
KROS	New	KEROS THERAPEUTICS INC	$2,089,360	–	52,000	–	0.26%	–
PTGX	New	PROTAGONIST THERAPEUTICS INC	$2,071,500	–	75,000	–	0.26%	–
ALLO	New	ALLOGENE THERAPEUTICS INC	$2,047,640	–	412,000	–	0.25%	–
ELAN	New	ELANCO ANIMAL HEALTH INC	$2,012,000	–	200,000	–	0.25%	–
TERN	New	TERNS PHARMACEUTICALS INC	$1,575,000	–	180,000	–	0.20%	–
DYN	New	DYNE THERAPEUTICS INC	$697,500	–	62,000	–	0.09%	–

Q4 2022

			Value		Shares		↓ Weighting
LBPH	Exit	LONGBOARD PHARMACEUTICALS IN	$0	–	-110,000	–	-0.08%	–
MGTA	Exit	MAGENTA THERAPEUTICS INC	$0	–	-377,000	–	-0.10%	–
MIRM	Exit	MIRUM PHARMACEUTICALS INC	$0	–	-50,000	–	-0.20%	–
FOLD	Exit	AMICUS THERAPEUTICS INC	$0	–	-130,000	–	-0.26%	–
	Exit	CINCOR PHARMA INC	$0	–	-50,000	–	-0.32%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB L	$0	–	-30,000	–	-0.36%	–
ARCT	Exit	ARCTURUS THERAPEUTICS HLDGS	$0	–	-130,000	–	-0.37%	–
DSGN	Exit	DESIGN THERAPEUTICS INC	$0	–	-125,000	–	-0.41%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-100,000	–	-0.55%	–
HRTX	Exit	HERON THERAPEUTICS INC	$0	–	-700,000	–	-0.57%	–
AMED	Exit	AMEDISYS INC	$0	–	-33,000	–	-0.62%	–
FMTX	Exit	FORMA THERAPEUTICS HLDGS INC	$0	–	-92,000	–	-0.64%	–
REPL	Exit	REPLIMUNE GROUP INC	$0	–	-200,000	–	-0.67%	–
LFST	Exit	LIFESTANCE HEALTH GROUP INC	$0	–	-525,000	–	-0.68%	–
	Exit	VENTYX BIOSCIENCES INC	$0	–	-100,000	–	-0.68%	–
SIBN	Exit	SI-BONE INC	$0	–	-200,000	–	-0.68%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-115,000	–	-0.69%	–
GOSS	Exit	GOSSAMER BIO INC	$0	–	-300,000	–	-0.70%	–
ITOS	Exit	ITEOS THERAPEUTICS INC	$0	–	-195,000	–	-0.72%	–
RVNC	Exit	REVANCE THERAPEUTICS INC	$0	–	-150,000	–	-0.79%	–
ALKS	Exit	ALKERMES PLC	$0	–	-200,000	–	-0.87%	–
NVRO	Exit	NEVRO CORP	$0	–	-100,000	–	-0.90%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-70,000	–	-0.93%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-150,000	–	-0.95%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-70,000	–	-0.95%	–
ACRS	Exit	ACLARIS THERAPEUTICS INC	$0	–	-340,000	–	-1.04%	–
ILMN	Exit	ILLUMINA INC	$0	–	-30,000	–	-1.11%	–
PODD	Exit	INSULET CORP	$0	–	-25,000	–	-1.11%	–
BPMC	Exit	BLUEPRINT MEDICINES CORP	$0	–	-93,000	–	-1.19%	–
DVA	Exit	DAVITA INC	$0	–	-75,000	–	-1.21%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-50,000	–	-1.22%	–
KRYS	Exit	KRYSTAL BIOTECH INC	$0	–	-90,000	–	-1.22%	–
THC	Exit	TENET HEALTHCARE CORP	$0	–	-130,000	–	-1.30%	–
ISEE	Exit	IVERIC BIO INC	$0	–	-375,000	–	-1.31%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-500,000	–	-1.33%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-125,000	–	-1.36%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-40,000	–	-1.38%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-15,000	–	-1.47%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-30,000	–	-1.50%	–
AKRO	Exit	AKERO THERAPEUTICS INC	$0	–	-230,000	–	-1.52%	–
LLY	Exit	LILLY ELI & CO	$0	–	-25,000	–	-1.57%	–
QURE	Exit	UNIQURE NV	$0	–	-433,000	–	-1.58%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-163,000	–	-1.59%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-107,000	–	-1.76%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-250,000	–	-1.85%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-90,000	–	-1.86%	–
MCK	Exit	MCKESSON CORP	$0	–	-30,000	–	-1.98%	–
PRGO	Exit	PERRIGO CO PLC	$0	–	-320,000	–	-2.22%	–
ZNTL	Exit	ZENTALIS PHARMACEUTICALS INC	$0	–	-550,000	–	-2.31%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-130,000	–	-2.41%	–
CAH	Exit	CARDINAL HEALTH INC	$0	–	-200,000	–	-2.59%	–
BIIB	Exit	BIOGEN INC	$0	–	-50,000	–	-2.59%	–
RLAY	Exit	RELAY THERAPEUTICS INC	$0	–	-600,000	–	-2.61%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-350,000	–	-2.63%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-357,000	–	-2.72%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-70,000	–	-2.72%	–
CRSP	Exit	CRISPR THERAPEUTICS AGnamen akt	$0	–	-220,000	–	-2.79%	–
NVST	Exit	ENVISTA HOLDINGS CORPORATION	$0	–	-440,000	–	-2.80%	–
MRK	Exit	MERCK & CO INC	$0	–	-185,000	–	-3.10%	–
BAX	Exit	BAXTER INTL INC	$0	–	-300,000	–	-3.14%	–
CYTK	Exit	CYTOKINETICS INC	$0	–	-350,000	–	-3.29%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-225,000	–	-3.40%	–
ANTM	Exit	ELEVANCE HEALTH INC	$0	–	-40,000	–	-3.53%	–
	Exit	CYTOKINETICS INCcall	$0	–	-456,300	–	-4.30%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-450,000	–	-4.71%	–

Q3 2022

			Value		Shares		↓ Weighting
GH	Buy	GUARDANT HEALTH INC	$24,224,000	+55.9%	450,000	+16.8%	4.71%	+47.2%
	New	CYTOKINETICS INCcall	$22,108,000	–	456,300	–	4.30%	–
ANTM	Sell	ELEVANCE HEALTH INC	$18,170,000	-44.5%	40,000	-41.0%	3.53%	-47.6%
CNC	Sell	CENTENE CORP DEL	$17,507,000	-40.9%	225,000	-35.7%	3.40%	-44.2%
CYTK	Sell	CYTOKINETICS INC	$16,958,000	-17.8%	350,000	-33.3%	3.29%	-22.4%
BAX	New	BAXTER INTL INC	$16,158,000	–	300,000	–	3.14%	–
MRK	Buy	MERCK & CO INC	$15,932,000	+67.4%	185,000	+77.3%	3.10%	+58.2%
NVST	Buy	ENVISTA HOLDINGS CORPORATION	$14,436,000	-3.0%	440,000	+13.9%	2.80%	-8.4%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$14,377,000	+195.7%	220,000	+175.0%	2.79%	+179.3%
ALNY	Buy	ALNYLAM PHARMACEUTICALS INC	$14,011,000	+104.5%	70,000	+49.0%	2.72%	+93.2%
SAGE	Sell	SAGE THERAPEUTICS INC	$13,980,000	+5.0%	357,000	-13.4%	2.72%	-0.8%
BSX	New	BOSTON SCIENTIFIC CORP	$13,556,000	–	350,000	–	2.63%	–
RLAY	Buy	RELAY THERAPEUTICS INC	$13,422,000	+83.7%	600,000	+37.5%	2.61%	+73.5%
BIIB	New	BIOGEN INC	$13,350,000	–	50,000	–	2.59%	–
CAH	New	CARDINAL HEALTH INC	$13,336,000	–	200,000	–	2.59%	–
CVS	Sell	CVS HEALTH CORP	$12,398,000	-5.0%	130,000	-7.7%	2.41%	-10.3%
ZNTL	Buy	ZENTALIS PHARMACEUTICALS INC	$11,913,000	+24.6%	550,000	+61.6%	2.31%	+17.6%
PRGO	Buy	PERRIGO CO PLC	$11,411,000	+54.0%	320,000	+75.2%	2.22%	+45.5%
MCK	Sell	MCKESSON CORP	$10,196,000	-25.1%	30,000	-28.1%	1.98%	-29.3%
NBIX	New	NEUROCRINE BIOSCIENCES INC	$9,559,000	–	90,000	–	1.86%	–
SNY	Sell	SANOFIsponsored adr	$9,505,000	-45.7%	250,000	-28.6%	1.85%	-48.8%
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$9,070,000	-13.3%	107,000	-15.3%	1.76%	-18.2%
PTCT	Buy	PTC THERAPEUTICS INC	$8,183,000	+95.2%	163,000	+55.7%	1.59%	+84.5%
QURE	Buy	UNIQURE NV	$8,123,000	+23.4%	433,000	+22.6%	1.58%	+16.5%
LLY	Sell	LILLY ELI & CO	$8,084,000	-65.9%	25,000	-65.8%	1.57%	-67.8%
AKRO	Sell	AKERO THERAPEUTICS INC	$7,832,000	+187.7%	230,000	-20.2%	1.52%	+171.6%
DHR	New	DANAHER CORPORATION	$7,749,000	–	30,000	–	1.50%	–
UNH	New	UNITEDHEALTH GROUP INC	$7,576,000	–	15,000	–	1.47%	–
INSP	New	INSPIRE MED SYS INC	$7,095,000	–	40,000	–	1.38%	–
NTLA	Buy	INTELLIA THERAPEUTICS INC	$6,995,000	+61.8%	125,000	+49.7%	1.36%	+52.9%
KURA	Buy	KURA ONCOLOGY INC	$6,830,000	-19.2%	500,000	+8.4%	1.33%	-23.7%
ISEE	New	IVERIC BIO INC	$6,728,000	–	375,000	–	1.31%	–
THC	Sell	TENET HEALTHCARE CORP	$6,705,000	-49.1%	130,000	-48.1%	1.30%	-51.9%
KRYS	Buy	KRYSTAL BIOTECH INC	$6,273,000	+83.1%	90,000	+72.5%	1.22%	+72.9%
IRTC	Sell	IRHYTHM TECHNOLOGIES INC	$6,264,000	+1.0%	50,000	-12.9%	1.22%	-4.6%
DVA	Buy	DAVITA INC	$6,208,000	+48.8%	75,000	+43.7%	1.21%	+40.6%
BPMC	Sell	BLUEPRINT MEDICINES CORP	$6,128,000	-6.7%	93,000	-28.5%	1.19%	-11.9%
PODD	New	INSULET CORP	$5,735,000	–	25,000	–	1.11%	–
ILMN	New	ILLUMINA INC	$5,724,000	–	30,000	–	1.11%	–
ACRS	Buy	ACLARIS THERAPEUTICS INC	$5,352,000	+34.1%	340,000	+18.9%	1.04%	+26.7%
MRTX	New	MIRATI THERAPEUTICS INC	$4,889,000	–	70,000	–	0.95%	–
EXAS	New	EXACT SCIENCES CORP	$4,874,000	–	150,000	–	0.95%	–
APLS	Sell	APELLIS PHARMACEUTICALS INC	$4,781,000	+6.6%	70,000	-29.4%	0.93%	+0.8%
NVRO	Buy	NEVRO CORP	$4,660,000	+35.8%	100,000	+27.8%	0.90%	+28.2%
ALKS	Sell	ALKERMES PLC	$4,466,000	-42.8%	200,000	-23.7%	0.87%	-45.9%
RVNC	New	REVANCE THERAPEUTICS INC	$4,050,000	–	150,000	–	0.79%	–
ITOS	Buy	ITEOS THERAPEUTICS INC	$3,715,000	+15.2%	195,000	+24.6%	0.72%	+8.9%
GOSS	New	GOSSAMER BIO INC	$3,594,000	–	300,000	–	0.70%	–
DNLI	New	DENALI THERAPEUTICS INC	$3,529,000	–	115,000	–	0.69%	–
	New	VENTYX BIOSCIENCES INC	$3,491,000	–	100,000	–	0.68%	–
SIBN	Buy	SI-BONE INC	$3,492,000	+68.1%	200,000	+27.1%	0.68%	+58.8%
LFST	Buy	LIFESTANCE HEALTH GROUP INC	$3,476,000	+66.4%	525,000	+39.7%	0.68%	+57.0%
REPL	Sell	REPLIMUNE GROUP INC	$3,454,000	-9.9%	200,000	-8.8%	0.67%	-14.8%
FMTX	Sell	FORMA THERAPEUTICS HLDGS INC	$3,306,000	+269.0%	92,000	-29.3%	0.64%	+248.9%
AMED	New	AMEDISYS INC	$3,194,000	–	33,000	–	0.62%	–
HRTX	Sell	HERON THERAPEUTICS INC	$2,954,000	+5.9%	700,000	-30.0%	0.57%	0.0%
AGIO	New	AGIOS PHARMACEUTICALS INC	$2,828,000	–	100,000	–	0.55%	–
DSGN	New	DESIGN THERAPEUTICS INC	$2,090,000	–	125,000	–	0.41%	–
ARCT	Sell	ARCTURUS THERAPEUTICS HLDGS	$1,927,000	-21.8%	130,000	-17.0%	0.37%	-26.2%
HZNP	New	HORIZON THERAPEUTICS PUB L	$1,857,000	–	30,000	–	0.36%	–
	Buy	CINCOR PHARMA INC	$1,641,000	+108.5%	50,000	+19.8%	0.32%	+96.9%
FOLD	Sell	AMICUS THERAPEUTICS INC	$1,357,000	-82.1%	130,000	-81.5%	0.26%	-83.0%
MIRM	Sell	MIRUM PHARMACEUTICALS INC	$1,051,000	-69.6%	50,000	-71.8%	0.20%	-71.3%
MGTA	Buy	MAGENTA THERAPEUTICS INC	$532,000	+35.0%	377,000	+14.8%	0.10%	+27.2%
LBPH	Buy	LONGBOARD PHARMACEUTICALS IN	$409,000	+131.1%	110,000	+91.9%	0.08%	+119.4%
LXRX	Exit	LEXICON PHARMACEUTICALS INC	$0	–	-300,000	–	-0.12%	–
ATRA	Exit	ATARA BIOTHERAPEUTICS INC	$0	–	-208,738	–	-0.33%	–
INSM	Exit	INSMED INC	$0	–	-104,369	–	-0.42%	–
KNSA	Exit	KINIKSA PHARMACEUTICALS LTD	$0	–	-234,830	–	-0.47%	–
NSTG	Exit	NANOSTRING TECHNOLOGIES INC	$0	–	-188,500	–	-0.49%	–
XENE	Exit	XENON PHARMACEUTICALS INC	$0	–	-97,281	–	-0.61%	–
RETA	Exit	REATA PHARMACEUTICALS INCcl a	$0	–	-104,369	–	-0.65%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-20,874	–	-0.67%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-124,369	–	-0.85%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-41,748	–	-0.90%	–
ITCI	Exit	INTRA-CELLULAR THERAPIES INC	$0	–	-78,277	–	-0.92%	–
AGL	Exit	AGILON HEALTH INC	$0	–	-230,655	–	-1.04%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-156,554	–	-1.12%	–
SGEN	Exit	SEAGEN INC	$0	–	-31,311	–	-1.14%	–
MRNA	Exit	MODERNA INC	$0	–	-40,000	–	-1.18%	–
ONEM	Exit	1LIFE HEALTHCARE INC	$0	–	-730,582	–	-1.18%	–
ICLR	Exit	ICON PLC	$0	–	-31,311	–	-1.40%	–
SWAV	Exit	SHOCKWAVE MED INC	$0	–	-46,966	–	-1.85%	–
PKI	Exit	PERKINELMER INC	$0	–	-67,840	–	-1.98%	–
DXCM	Exit	DEXCOM INC	$0	–	-166,991	–	-2.56%	–
CCXI	Exit	CHEMOCENTRYX INC	$0	–	-574,029	–	-2.93%	–
AZN	Exit	ASTRAZENECA PLCsponsored adr	$0	–	-234,830	–	-3.19%	–

Q2 2022

			Value		Shares		↓ Weighting
ANTM	New	ELEVANCE HEALTH INC	$32,738,000	–	67,840	–	6.73%	–
CNC	New	CENTENE CORP DEL	$29,614,000	–	350,000	–	6.09%	–
LLY	New	LILLY ELI & CO	$23,688,000	–	73,059	–	4.87%	–
CYTK	New	CYTOKINETICS INC	$20,627,000	–	525,000	–	4.24%	–
SNY	New	SANOFIsponsored adr	$17,511,000	–	350,000	–	3.60%	–
GH	New	GUARDANT HEALTH INC	$15,543,000	–	385,291	–	3.20%	–
AZN	New	ASTRAZENECA PLCsponsored adr	$15,515,000	–	234,830	–	3.19%	–
NVST	New	ENVISTA HOLDINGS CORPORATION	$14,883,000	–	386,165	–	3.06%	–
CCXI	New	CHEMOCENTRYX INC	$14,224,000	–	574,029	–	2.93%	–
MCK	New	MCKESSON CORP	$13,619,000	–	41,748	–	2.80%	–
SAGE	New	SAGE THERAPEUTICS INC	$13,316,000	–	412,257	–	2.74%	–
THC	New	TENET HEALTHCARE CORP	$13,165,000	–	250,485	–	2.71%	–
CVS	New	CVS HEALTH CORP	$13,056,000	–	140,898	–	2.69%	–
DXCM	New	DEXCOM INC	$12,446,000	–	166,991	–	2.56%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$10,465,000	–	126,286	–	2.15%	–
PKI	New	PERKINELMER INC	$9,648,000	–	67,840	–	1.98%	–
ZNTL	New	ZENTALIS PHARMACEUTICALS INC	$9,561,000	–	340,243	–	1.97%	–
MRK	New	MERCK & CO INC	$9,515,000	–	104,369	–	1.96%	–
SWAV	New	SHOCKWAVE MED INC	$8,978,000	–	46,966	–	1.85%	–
KURA	New	KURA ONCOLOGY INC	$8,456,000	–	461,310	–	1.74%	–
ALKS	New	ALKERMES PLC	$7,804,000	–	261,966	–	1.60%	–
FOLD	New	AMICUS THERAPEUTICS INC	$7,566,000	–	704,490	–	1.56%	–
PRGO	New	PERRIGO CO PLC	$7,410,000	–	182,645	–	1.52%	–
RLAY	New	RELAY THERAPEUTICS INC	$7,307,000	–	436,262	–	1.50%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$6,850,000	–	46,966	–	1.41%	–
ICLR	New	ICON PLC	$6,785,000	–	31,311	–	1.40%	–
QURE	New	UNIQURE NV	$6,582,000	–	353,106	–	1.35%	–
BPMC	New	BLUEPRINT MEDICINES CORP	$6,566,000	–	130,000	–	1.35%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$6,201,000	–	57,403	–	1.28%	–
ONEM	New	1LIFE HEALTHCARE INC	$5,728,000	–	730,582	–	1.18%	–
MRNA	New	MODERNA INC	$5,714,000	–	40,000	–	1.18%	–
SGEN	New	SEAGEN INC	$5,540,000	–	31,311	–	1.14%	–
ZLAB	New	ZAI LAB LTDadr	$5,429,000	–	156,554	–	1.12%	–
AGL	New	AGILON HEALTH INC	$5,035,000	–	230,655	–	1.04%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$4,862,000	–	80,010	–	1.00%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$4,484,000	–	99,150	–	0.92%	–
ITCI	New	INTRA-CELLULAR THERAPIES INC	$4,468,000	–	78,277	–	0.92%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$4,386,000	–	41,748	–	0.90%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$4,322,000	–	83,495	–	0.89%	–
PTCT	New	PTC THERAPEUTICS INC	$4,193,000	–	104,656	–	0.86%	–
DVA	New	DAVITA INC	$4,173,000	–	52,184	–	0.86%	–
TDOC	New	TELADOC HEALTH INC	$4,130,000	–	124,369	–	0.85%	–
ACRS	New	ACLARIS THERAPEUTICS INC	$3,992,000	–	285,971	–	0.82%	–
REPL	New	REPLIMUNE GROUP INC	$3,832,000	–	219,194	–	0.79%	–
MIRM	New	MIRUM PHARMACEUTICALS INC	$3,453,000	–	177,427	–	0.71%	–
NVRO	New	NEVRO CORP	$3,431,000	–	78,277	–	0.71%	–
KRYS	New	KRYSTAL BIOTECH INC	$3,426,000	–	52,184	–	0.70%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$3,257,000	–	20,874	–	0.67%	–
ITOS	New	ITEOS THERAPEUTICS INC	$3,225,000	–	156,553	–	0.66%	–
RETA	New	REATA PHARMACEUTICALS INCcl a	$3,172,000	–	104,369	–	0.65%	–
XENE	New	XENON PHARMACEUTICALS INC	$2,959,000	–	97,281	–	0.61%	–
HRTX	New	HERON THERAPEUTICS INC	$2,790,000	–	1,000,000	–	0.57%	–
AKRO	New	AKERO THERAPEUTICS INC	$2,722,000	–	288,058	–	0.56%	–
ARCT	New	ARCTURUS THERAPEUTICS HLDGS	$2,464,000	–	156,553	–	0.51%	–
NSTG	New	NANOSTRING TECHNOLOGIES INC	$2,394,000	–	188,500	–	0.49%	–
KNSA	New	KINIKSA PHARMACEUTICALS LTD	$2,276,000	–	234,830	–	0.47%	–
LFST	New	LIFESTANCE HEALTH GROUP INC	$2,089,000	–	375,728	–	0.43%	–
SIBN	New	SI-BONE INC	$2,077,000	–	157,317	–	0.43%	–
INSM	New	INSMED INC	$2,058,000	–	104,369	–	0.42%	–
ATRA	New	ATARA BIOTHERAPEUTICS INC	$1,626,000	–	208,738	–	0.33%	–
FMTX	New	FORMA THERAPEUTICS HLDGS INC	$896,000	–	130,051	–	0.18%	–
	New	CINCOR PHARMA INC	$787,000	–	41,748	–	0.16%	–
LXRX	New	LEXICON PHARMACEUTICALS INC	$558,000	–	300,000	–	0.12%	–
MGTA	New	MAGENTA THERAPEUTICS INC	$394,000	–	328,269	–	0.08%	–
LBPH	New	LONGBOARD PHARMACEUTICALS IN	$177,000	–	57,335	–	0.04%	–

Q4 2021

			Value		Shares		↓ Weighting
LBPH	Exit	LONGBOARD PHARMACEUTICALS IN	$0	–	-30,000	–	-0.08%	–
CMRX	Exit	CHIMERIX INC	$0	–	-90,000	–	-0.16%	–
PTGX	Exit	PROTAGONIST THERAPEUTICS INC	$0	–	-35,000	–	-0.18%	–
MGTA	Exit	MAGENTA THERAPEUTICS INC	$0	–	-90,000	–	-0.19%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-20,000	–	-0.26%	–
AVIR	Exit	ATEA PHARMACEUTICALS INC	$0	–	-30,000	–	-0.30%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-60,000	–	-0.32%	–
FMTX	Exit	FORMA THERAPEUTICS HLDGS INC	$0	–	-60,000	–	-0.40%	–
RVNC	Exit	REVANCE THERAPEUTICS INC	$0	–	-50,000	–	-0.40%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-18,000	–	-0.40%	–
DTIL	Exit	PRECISION BIOSCIENCES INC	$0	–	-125,000	–	-0.42%	–
ZYME	Exit	ZYMEWORKS INC	$0	–	-50,000	–	-0.42%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-65,000	–	-0.42%	–
LXRX	Exit	LEXICON PHARMACEUTICALS INC	$0	–	-350,000	–	-0.48%	–
IMGN	Exit	IMMUNOGEN INC	$0	–	-300,000	–	-0.49%	–
AKRO	Exit	AKERO THERAPEUTICS INC	$0	–	-85,000	–	-0.55%	–
LYEL	Exit	LYELL IMMUNOPHARMA INC	$0	–	-140,000	–	-0.60%	–
ZY	Exit	ZYMERGEN INC	$0	–	-160,000	–	-0.61%	–
RGNX	Exit	REGENXBIO INC	$0	–	-55,000	–	-0.66%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-10,000	–	-0.67%	–
REPL	Exit	REPLIMUNE GROUP INC	$0	–	-90,000	–	-0.77%	–
INSM	Exit	INSMED INC	$0	–	-100,000	–	-0.79%	–
BHVN	Exit	BIOHAVEN PHARMACTL HLDG CO L	$0	–	-20,000	–	-0.80%	–
AERI	Exit	AERIE PHARMACEUTICALS INC	$0	–	-250,000	–	-0.82%	–
ACRS	Exit	ACLARIS THERAPEUTICS INC	$0	–	-185,000	–	-0.96%	–
MGNX	Exit	MACROGENICS INC	$0	–	-160,000	–	-0.96%	–
NVRO	Exit	NEVRO CORP	$0	–	-30,000	–	-1.00%	–
RETA	Exit	REATA PHARMACEUTICALS INCcl a	$0	–	-35,000	–	-1.01%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-20,000	–	-1.02%	–
	Exit	AVALO THERAPEUTICS INC	$0	–	-1,625,000	–	-1.02%	–
ATRA	Exit	ATARA BIOTHERAPEUTICS INC	$0	–	-200,000	–	-1.03%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-97,100	–	-1.04%	–
SIBN	Exit	SI-BONE INC	$0	–	-170,000	–	-1.05%	–
ABBV	Exit	ABBVIE INC	$0	–	-35,000	–	-1.08%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-75,000	–	-1.09%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-35,000	–	-1.14%	–
FOLD	Exit	AMICUS THERAPEUTICS INC	$0	–	-425,000	–	-1.17%	–
ARCT	Exit	ARCTURUS THERAPEUTICS HLDGS	$0	–	-85,000	–	-1.17%	–
UHS	Exit	UNIVERSAL HLTH SVCS INCcl b	$0	–	-30,000	–	-1.19%	–
HRTX	Exit	HERON THERAPEUTICS INC	$0	–	-410,000	–	-1.26%	–
RLAY	Exit	RELAY THERAPEUTICS INC	$0	–	-140,000	–	-1.27%	–
NTRA	Exit	NATERA INC	$0	–	-40,000	–	-1.28%	–
AGL	Exit	AGILON HEALTH INC	$0	–	-180,000	–	-1.36%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-25,000	–	-1.36%	–
ABC	Exit	AMERISOURCEBERGEN CORP	$0	–	-40,000	–	-1.37%	–
LFST	Exit	LIFESTANCE HEALTH GROUP INC	$0	–	-350,000	–	-1.46%	–
CCXI	Exit	CHEMOCENTRYX INC	$0	–	-300,000	–	-1.48%	–
DXCM	Exit	DEXCOM INC	$0	–	-10,000	–	-1.57%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-95,000	–	-1.62%	–
ZNTL	Exit	ZENTALIS PHARMACEUTICALS INC	$0	–	-90,000	–	-1.72%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-10,000	–	-1.74%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-100,000	–	-1.79%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-190,000	–	-1.80%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB L	$0	–	-60,000	–	-1.89%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-50,000	–	-1.93%	–
SGEN	Exit	SEAGEN INC	$0	–	-40,000	–	-1.95%	–
PKI	Exit	PERKINELMER INC	$0	–	-50,000	–	-2.49%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-60,000	–	-2.52%	–
HOLX	Exit	HOLOGIC INC	$0	–	-120,000	–	-2.55%	–
ANTM	Exit	ANTHEM INC	$0	–	-25,000	–	-2.68%	–
NVST	Exit	ENVISTA HOLDINGS CORPORATION	$0	–	-230,000	–	-2.76%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-80,000	–	-2.88%	–
BPMC	Exit	BLUEPRINT MEDICINES CORP	$0	–	-98,000	–	-2.90%	–
PFE	Exit	PFIZER INC	$0	–	-250,000	–	-3.09%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-150,000	–	-3.30%	–
CYTK	Exit	CYTOKINETICS INC	$0	–	-325,000	–	-3.34%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-150,000	–	-3.66%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-319,000	–	-4.06%	–
ACHC	Exit	ACADIA HEALTHCARE COMPANY IN	$0	–	-255,000	–	-4.68%	–
ARNA	Exit	ARENA PHARMACEUTICALS INC	$0	–	-300,000	–	-5.14%	–

Q3 2021

			Value		Shares		↓ Weighting
ARNA	Buy	ARENA PHARMACEUTICALS INC	$17,865,000	+16.4%	300,000	+33.3%	5.14%	+21.6%
ACHC	Sell	ACADIA HEALTHCARE COMPANY IN	$16,264,000	-0.3%	255,000	-1.9%	4.68%	+4.1%
SAGE	Buy	SAGE THERAPEUTICS INC	$14,135,000	+11.1%	319,000	+42.4%	4.06%	+16.0%
CVS	New	CVS HEALTH CORP	$12,729,000	–	150,000	–	3.66%	–
CYTK	Sell	CYTOKINETICS INC	$11,616,000	-16.1%	325,000	-53.6%	3.34%	-12.5%
GMED	Buy	GLOBUS MED INCcl a	$11,493,000	+14.0%	150,000	+15.4%	3.30%	+19.1%
PFE	New	PFIZER INC	$10,753,000	–	250,000	–	3.09%	–
BPMC	Sell	BLUEPRINT MEDICINES CORP	$10,075,000	+14.5%	98,000	-2.0%	2.90%	+19.6%
NVST	Buy	ENVISTA HOLDINGS CORPORATION	$9,616,000	+23.6%	230,000	+27.8%	2.76%	+29.1%
ANTM	Sell	ANTHEM INC	$9,320,000	-51.2%	25,000	-50.0%	2.68%	-49.0%
HOLX	New	HOLOGIC INC	$8,857,000	–	120,000	–	2.55%	–
ZBH	Buy	ZIMMER BIOMET HOLDINGS INC	$8,782,000	+56.0%	60,000	+71.4%	2.52%	+62.9%
PKI	Buy	PERKINELMER INC	$8,665,000	+40.3%	50,000	+25.0%	2.49%	+46.5%
SGEN	New	SEAGEN INC	$6,792,000	–	40,000	–	1.95%	–
NTLA	Buy	INTELLIA THERAPEUTICS INC	$6,708,000	+38.1%	50,000	+66.7%	1.93%	+44.2%
HZNP	New	HORIZON THERAPEUTICS PUB L	$6,572,000	–	60,000	–	1.89%	–
APLS	Buy	APELLIS PHARMACEUTICALS INC	$6,262,000	+183.1%	190,000	+442.9%	1.80%	+195.6%
CNC	New	CENTENE CORP DEL	$6,231,000	–	100,000	–	1.79%	–
REGN	Sell	REGENERON PHARMACEUTICALS	$6,052,000	-41.4%	10,000	-45.9%	1.74%	-38.8%
ZNTL	Sell	ZENTALIS PHARMACEUTICALS INC	$5,998,000	-9.8%	90,000	-28.0%	1.72%	-5.8%
FATE	Buy	FATE THERAPEUTICS INC	$5,631,000	-18.9%	95,000	+18.8%	1.62%	-15.3%
DXCM	New	DEXCOM INC	$5,469,000	–	10,000	–	1.57%	–
CCXI	Buy	CHEMOCENTRYX INC	$5,130,000	+119.0%	300,000	+71.4%	1.48%	+128.7%
LFST	New	LIFESTANCE HEALTH GROUP INC	$5,075,000	–	350,000	–	1.46%	–
ABC	Sell	AMERISOURCEBERGEN CORP	$4,778,000	-40.4%	40,000	-42.9%	1.37%	-37.7%
AGL	Buy	AGILON HEALTH INC	$4,718,000	+16.3%	180,000	+80.0%	1.36%	+21.4%
NTRA	Sell	NATERA INC	$4,458,000	-28.6%	40,000	-27.3%	1.28%	-25.4%
RLAY	Buy	RELAY THERAPEUTICS INC	$4,414,000	+0.5%	140,000	+16.7%	1.27%	+5.0%
HRTX	Buy	HERON THERAPEUTICS INC	$4,383,000	+182.4%	410,000	+310.0%	1.26%	+195.1%
UHS	Sell	UNIVERSAL HLTH SVCS INCcl b	$4,151,000	-56.4%	30,000	-53.8%	1.19%	-54.5%
FOLD	Sell	AMICUS THERAPEUTICS INC	$4,059,000	-11.4%	425,000	-10.5%	1.17%	-7.5%
ARCT	New	ARCTURUS THERAPEUTICS HLDGS	$4,061,000	–	85,000	–	1.17%	–
EW	Sell	EDWARDS LIFESCIENCES CORP	$3,962,000	-41.1%	35,000	-46.2%	1.14%	-38.5%
DNLI	Sell	DENALI THERAPEUTICS INC	$3,784,000	-40.4%	75,000	-7.4%	1.09%	-37.8%
ABBV	New	ABBVIE INC	$3,775,000	–	35,000	–	1.08%	–
SIBN	Buy	SI-BONE INC	$3,641,000	+28.6%	170,000	+88.9%	1.05%	+34.2%
PTCT	Sell	PTC THERAPEUTICS INC	$3,613,000	-22.4%	97,100	-11.8%	1.04%	-18.9%
ATRA	New	ATARA BIOTHERAPEUTICS INC	$3,580,000	–	200,000	–	1.03%	–
	New	AVALO THERAPEUTICS INC	$3,543,000	–	1,625,000	–	1.02%	–
MRTX	Sell	MIRATI THERAPEUTICS INC	$3,538,000	-56.2%	20,000	-60.0%	1.02%	-54.3%
RETA	Sell	REATA PHARMACEUTICALS INCcl a	$3,521,000	-40.8%	35,000	-16.7%	1.01%	-38.1%
NVRO	Sell	NEVRO CORP	$3,491,000	-44.6%	30,000	-21.1%	1.00%	-42.1%
MGNX	New	MACROGENICS INC	$3,350,000	–	160,000	–	0.96%	–
ACRS	Buy	ACLARIS THERAPEUTICS INC	$3,330,000	+8.4%	185,000	+5.7%	0.96%	+13.1%
AERI	Sell	AERIE PHARMACEUTICALS INC	$2,850,000	-56.6%	250,000	-39.0%	0.82%	-54.7%
BHVN	New	BIOHAVEN PHARMACTL HLDG CO L	$2,778,000	–	20,000	–	0.80%	–
INSM	New	INSMED INC	$2,754,000	–	100,000	–	0.79%	–
INSP	New	INSPIRE MED SYS INC	$2,329,000	–	10,000	–	0.67%	–
RGNX	New	REGENXBIO INC	$2,306,000	–	55,000	–	0.66%	–
ZY	New	ZYMERGEN INC	$2,107,000	–	160,000	–	0.61%	–
LYEL	New	LYELL IMMUNOPHARMA INC	$2,072,000	–	140,000	–	0.60%	–
IMGN	New	IMMUNOGEN INC	$1,701,000	–	300,000	–	0.49%	–
LXRX	New	LEXICON PHARMACEUTICALS INC	$1,684,000	–	350,000	–	0.48%	–
MYOV	Sell	MYOVANT SCIENCES LTD	$1,459,000	-24.6%	65,000	-23.5%	0.42%	-21.4%
ZYME	New	ZYMEWORKS INC	$1,452,000	–	50,000	–	0.42%	–
DTIL	Sell	PRECISION BIOSCIENCES INC	$1,443,000	-34.1%	125,000	-28.6%	0.42%	-31.2%
RVNC	New	REVANCE THERAPEUTICS INC	$1,393,000	–	50,000	–	0.40%	–
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$1,391,000	-33.3%	18,000	-28.0%	0.40%	-30.3%
FMTX	Buy	FORMA THERAPEUTICS HLDGS INC	$1,391,000	+24.2%	60,000	+33.3%	0.40%	+29.9%
KURA	Sell	KURA ONCOLOGY INC	$1,124,000	-23.0%	60,000	-14.3%	0.32%	-19.7%
AVIR	New	ATEA PHARMACEUTICALS INC	$1,052,000	–	30,000	–	0.30%	–
AGIO	Sell	AGIOS PHARMACEUTICALS INC	$923,000	-44.2%	20,000	-33.3%	0.26%	-41.8%
MGTA	Buy	MAGENTA THERAPEUTICS INC	$655,000	-10.8%	90,000	+20.0%	0.19%	-6.9%
PTGX	New	PROTAGONIST THERAPEUTICS INC	$620,000	–	35,000	–	0.18%	–
CMRX	Buy	CHIMERIX INC	$557,000	-7.2%	90,000	+20.0%	0.16%	-3.0%
ARDX	Exit	ARDELYX INC	$0	–	-70,000	–	-0.15%	–
ALEC	Exit	ALECTOR INC	$0	–	-35,000	–	-0.20%	–
KDMN	Exit	KADMON HLDGS INC	$0	–	-225,000	–	-0.24%	–
MSON	Exit	MISONIX INC	$0	–	-45,000	–	-0.28%	–
	Exit	TRILLIUM THERAPEUTICS INC	$0	–	-150,000	–	-0.40%	–
AXGN	Exit	AXOGEN INC	$0	–	-70,000	–	-0.42%	–
KPTI	Exit	KARYOPHARM THERAPEUTICS INC	$0	–	-150,000	–	-0.43%	–
ALT	Exit	ALTIMMUNE INC	$0	–	-160,000	–	-0.43%	–
ONEM	Exit	1LIFE HEALTHCARE INC	$0	–	-50,000	–	-0.46%	–
MCRB	Exit	SERES THERAPEUTICS INC	$0	–	-75,000	–	-0.49%	–
BCRX	Exit	BIOCRYST PHARMACEUTICALS INC	$0	–	-125,000	–	-0.54%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-5,000	–	-0.55%	–
CERC	Exit	CERECOR INC	$0	–	-675,000	–	-0.61%	–
AXNX	Exit	AXONICS INC	$0	–	-40,000	–	-0.70%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-50,000	–	-0.91%	–
PNTG	Exit	PENNANT GROUP INC	$0	–	-90,000	–	-1.01%	–
ALKS	Exit	ALKERMES PLC	$0	–	-150,000	–	-1.01%	–
BNTX	Exit	BIONTECH SEsponsored ads	$0	–	-17,000	–	-1.05%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-15,000	–	-1.11%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-25,000	–	-1.22%	–
ACCD	Exit	ACCOLADE INC	$0	–	-100,000	–	-1.50%	–
A	Exit	AGILENT TECHNOLOGIES INC	$0	–	-40,000	–	-1.63%	–
TFX	Exit	TELEFLEX INCORPORATED	$0	–	-20,000	–	-2.21%	–
LHCG	Exit	LHC GROUP INC	$0	–	-42,000	–	-2.32%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-175,000	–	-2.54%	–
BIIB	Exit	BIOGEN INC	$0	–	-35,000	–	-3.34%	–

Q2 2021

			Value		Shares		↓ Weighting
ANTM	New	ANTHEM INC	$19,090,000	–	50,000	–	5.26%	–
ACHC	New	ACADIA HEALTHCARE COMPANY IN	$16,315,000	–	260,000	–	4.49%	–
ARNA	New	ARENA PHARMACEUTICALS INC	$15,345,000	–	225,000	–	4.22%	–
CYTK	New	CYTOKINETICS INC	$13,853,000	–	700,000	–	3.81%	–
SAGE	New	SAGE THERAPEUTICS INC	$12,725,000	–	224,000	–	3.50%	–
BIIB	New	BIOGEN INC	$12,119,000	–	35,000	–	3.34%	–
REGN	New	REGENERON PHARMACEUTICALS	$10,333,000	–	18,500	–	2.84%	–
GMED	New	GLOBUS MED INCcl a	$10,079,000	–	130,000	–	2.78%	–
MDT	New	MEDTRONIC PLC	$9,930,000	–	80,000	–	2.73%	–
UHS	New	UNIVERSAL HLTH SVCS INCcl b	$9,518,000	–	65,000	–	2.62%	–
SNY	New	SANOFIsponsored adr	$9,216,000	–	175,000	–	2.54%	–
BPMC	New	BLUEPRINT MEDICINES CORP	$8,796,000	–	100,000	–	2.42%	–
LHCG	New	LHC GROUP INC	$8,411,000	–	42,000	–	2.32%	–
MRTX	New	MIRATI THERAPEUTICS INC	$8,077,000	–	50,000	–	2.22%	–
TFX	New	TELEFLEX INCORPORATED	$8,036,000	–	20,000	–	2.21%	–
ABC	New	AMERISOURCEBERGEN CORP	$8,014,000	–	70,000	–	2.21%	–
NVST	New	ENVISTA HOLDINGS CORPORATION	$7,778,000	–	180,000	–	2.14%	–
FATE	New	FATE THERAPEUTICS INC	$6,943,000	–	80,000	–	1.91%	–
EW	New	EDWARDS LIFESCIENCES CORP	$6,732,000	–	65,000	–	1.85%	–
ZNTL	New	ZENTALIS PHARMACEUTICALS INC	$6,650,000	–	125,000	–	1.83%	–
AERI	New	AERIE PHARMACEUTICALS INC	$6,564,000	–	410,000	–	1.81%	–
DNLI	New	DENALI THERAPEUTICS INC	$6,354,000	–	81,000	–	1.75%	–
NVRO	New	NEVRO CORP	$6,300,000	–	38,000	–	1.73%	–
NTRA	New	NATERA INC	$6,244,000	–	55,000	–	1.72%	–
PKI	New	PERKINELMER INC	$6,176,000	–	40,000	–	1.70%	–
RETA	New	REATA PHARMACEUTICALS INCcl a	$5,944,000	–	42,000	–	1.64%	–
A	New	AGILENT TECHNOLOGIES INC	$5,912,000	–	40,000	–	1.63%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$5,629,000	–	35,000	–	1.55%	–
ACCD	New	ACCOLADE INC	$5,431,000	–	100,000	–	1.50%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$4,857,000	–	30,000	–	1.34%	–
PTCT	New	PTC THERAPEUTICS INC	$4,654,000	–	110,100	–	1.28%	–
FOLD	New	AMICUS THERAPEUTICS INC	$4,579,000	–	475,000	–	1.26%	–
ZLAB	New	ZAI LAB LTDadr	$4,425,000	–	25,000	–	1.22%	–
RLAY	New	RELAY THERAPEUTICS INC	$4,391,000	–	120,000	–	1.21%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$4,238,000	–	25,000	–	1.17%	–
AGL	New	AGILON HEALTH INC	$4,057,000	–	100,000	–	1.12%	–
DHR	New	DANAHER CORPORATION	$4,025,000	–	15,000	–	1.11%	–
BNTX	New	BIONTECH SEsponsored ads	$3,806,000	–	17,000	–	1.05%	–
PNTG	New	PENNANT GROUP INC	$3,681,000	–	90,000	–	1.01%	–
ALKS	New	ALKERMES PLC	$3,678,000	–	150,000	–	1.01%	–
REPL	New	REPLIMUNE GROUP INC	$3,458,000	–	90,000	–	0.95%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$3,318,000	–	50,000	–	0.91%	–
ACRS	New	ACLARIS THERAPEUTICS INC	$3,073,000	–	175,000	–	0.85%	–
SIBN	New	SI-BONE INC	$2,832,000	–	90,000	–	0.78%	–
AXNX	New	AXONICS INC	$2,536,000	–	40,000	–	0.70%	–
CCXI	New	CHEMOCENTRYX INC	$2,343,000	–	175,000	–	0.64%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$2,212,000	–	35,000	–	0.61%	–
CERC	New	CERECOR INC	$2,207,000	–	675,000	–	0.61%	–
DTIL	New	PRECISION BIOSCIENCES INC	$2,191,000	–	175,000	–	0.60%	–
AKRO	New	AKERO THERAPEUTICS INC	$2,109,000	–	85,000	–	0.58%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$2,086,000	–	25,000	–	0.57%	–
UNH	New	UNITEDHEALTH GROUP INC	$2,002,000	–	5,000	–	0.55%	–
BCRX	New	BIOCRYST PHARMACEUTICALS INC	$1,976,000	–	125,000	–	0.54%	–
MYOV	New	MYOVANT SCIENCES LTD	$1,935,000	–	85,000	–	0.53%	–
MCRB	New	SERES THERAPEUTICS INC	$1,789,000	–	75,000	–	0.49%	–
ONEM	New	1LIFE HEALTHCARE INC	$1,653,000	–	50,000	–	0.46%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$1,653,000	–	30,000	–	0.46%	–
ALT	New	ALTIMMUNE INC	$1,576,000	–	160,000	–	0.43%	–
HRTX	New	HERON THERAPEUTICS INC	$1,552,000	–	100,000	–	0.43%	–
KPTI	New	KARYOPHARM THERAPEUTICS INC	$1,548,000	–	150,000	–	0.43%	–
AXGN	New	AXOGEN INC	$1,513,000	–	70,000	–	0.42%	–
KURA	New	KURA ONCOLOGY INC	$1,460,000	–	70,000	–	0.40%	–
	New	TRILLIUM THERAPEUTICS INC	$1,455,000	–	150,000	–	0.40%	–
FMTX	New	FORMA THERAPEUTICS HLDGS INC	$1,120,000	–	45,000	–	0.31%	–
MSON	New	MISONIX INC	$998,000	–	45,000	–	0.28%	–
KDMN	New	KADMON HLDGS INC	$871,000	–	225,000	–	0.24%	–
MGTA	New	MAGENTA THERAPEUTICS INC	$734,000	–	75,000	–	0.20%	–
ALEC	New	ALECTOR INC	$729,000	–	35,000	–	0.20%	–
CMRX	New	CHIMERIX INC	$600,000	–	75,000	–	0.16%	–
ARDX	New	ARDELYX INC	$531,000	–	70,000	–	0.15%	–
LBPH	New	LONGBOARD PHARMACEUTICALS IN	$274,000	–	30,000	–	0.08%	–

Q4 2020

			Value		Shares		↓ Weighting
ALEC	Exit	ALECTOR INC	$0	–	-30,000	–	-0.10%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-50,000	–	-0.22%	–
CHNG	Exit	CHANGE HEALTHCARE INC	$0	–	-50,000	–	-0.22%	–
INSM	Exit	INSMED INC	$0	–	-25,000	–	-0.25%	–
MCRB	Exit	SERES THERAPEUTICS INC	$0	–	-30,000	–	-0.26%	–
GMAB	Exit	GENMAB A/Ssponsored ads	$0	–	-30,000	–	-0.34%	–
	Exit	INOVIO PHARMACEUTICALS INCput	$0	–	-100,000	–	-0.36%	–
	Exit	GOSSAMER BIO INCcall	$0	–	-100,000	–	-0.38%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-30,100	–	-0.43%	–
DRNA	Exit	DICERNA PHARMACEUTICALS INC	$0	–	-80,000	–	-0.44%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-50,000	–	-0.47%	–
GNMK	Exit	GENMARK DIAGNOSTICS INC	$0	–	-125,000	–	-0.54%	–
KNSA	Exit	KINIKSA PHARMACEUTICALS LTD	$0	–	-120,000	–	-0.56%	–
DTIL	Exit	PRECISION BIOSCIENCES INC	$0	–	-300,000	–	-0.56%	–
SWAV	Exit	SHOCKWAVE MED INC	$0	–	-25,000	–	-0.58%	–
CHWY	Exit	CHEWY INCcl a	$0	–	-35,000	–	-0.59%	–
GKOS	Exit	GLAUKOS CORP	$0	–	-40,000	–	-0.61%	–
ACHC	Exit	ACADIA HEALTHCARE COMPANY IN	$0	–	-70,000	–	-0.63%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-25,000	–	-0.64%	–
MGNX	Exit	MACROGENICS INC	$0	–	-90,000	–	-0.69%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB L	$0	–	-30,000	–	-0.71%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-30,000	–	-0.73%	–
DXCM	Exit	DEXCOM INC	$0	–	-6,000	–	-0.76%	–
GOSS	Exit	GOSSAMER BIO INC	$0	–	-200,000	–	-0.76%	–
KPTI	Exit	KARYOPHARM THERAPEUTICS INC	$0	–	-175,000	–	-0.78%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-100,000	–	-0.78%	–
AKRO	Exit	AKERO THERAPEUTICS INC	$0	–	-85,000	–	-0.80%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-90,000	–	-0.83%	–
BHC	Exit	BAUSCH HEALTH COS INC	$0	–	-175,000	–	-0.83%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-15,000	–	-0.84%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-12,000	–	-0.87%	–
PNTG	Exit	PENNANT GROUP INC	$0	–	-75,000	–	-0.88%	–
CTLT	Exit	CATALENT INC	$0	–	-35,000	–	-0.92%	–
BMY	Exit	BRISTOL-MYERS SQUIBB CO	$0	–	-50,000	–	-0.92%	–
UHS	Exit	UNIVERSAL HLTH SVCS INCcl b	$0	–	-30,000	–	-0.98%	–
BAX	Exit	BAXTER INTL INC	$0	–	-40,000	–	-0.98%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-65,000	–	-0.98%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-30,000	–	-1.03%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-85,000	–	-1.04%	–
	Exit	MODERNA INCput	$0	–	-50,000	–	-1.08%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-25,000	–	-1.11%	–
HOLX	Exit	HOLOGIC INC	$0	–	-55,000	–	-1.12%	–
RETA	Exit	REATA PHARMACEUTICALS INCcl a	$0	–	-40,000	–	-1.19%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-155,000	–	-1.25%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-14,500	–	-1.27%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-120,000	–	-1.28%	–
CYTK	Exit	CYTOKINETICS INC	$0	–	-200,000	–	-1.32%	–
	Exit	CYTOKINETICS INCcall	$0	–	-200,000	–	-1.32%	–
NTRA	Exit	NATERA INC	$0	–	-66,000	–	-1.46%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-30,000	–	-1.52%	–
PODD	Exit	INSULET CORP	$0	–	-22,000	–	-1.59%	–
EHTH	Exit	EHEALTH INC	$0	–	-70,000	–	-1.69%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-95,000	–	-1.70%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-165,000	–	-1.81%	–
NVST	Exit	ENVISTA HOLDINGS CORPORATION	$0	–	-250,000	–	-1.89%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-125,000	–	-1.92%	–
GWPH	Exit	GW PHARMACEUTICALS PLCads	$0	–	-65,000	–	-1.94%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-50,000	–	-2.08%	–
CRL	Exit	CHARLES RIV LABS INTL INC	$0	–	-33,000	–	-2.29%	–
MRK	Exit	MERCK & CO. INC	$0	–	-100,000	–	-2.54%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-120,000	–	-2.79%	–
MCK	Exit	MCKESSON CORP	$0	–	-62,000	–	-2.82%	–
NVRO	Exit	NEVRO CORP	$0	–	-68,000	–	-2.90%	–
ABC	Exit	AMERISOURCEBERGEN CORP	$0	–	-100,000	–	-2.96%	–
BPMC	Exit	BLUEPRINT MEDICINES CORP	$0	–	-105,000	–	-2.98%	–
CCXI	Exit	CHEMOCENTRYX INC	$0	–	-185,000	–	-3.10%	–
HUM	Exit	HUMANA INC	$0	–	-26,000	–	-3.29%	–
ARNA	Exit	ARENA PHARMACEUTICALS INC	$0	–	-150,000	–	-3.43%	–
ABT	Exit	ABBOTT LABS	$0	–	-110,000	–	-3.66%	–
PKI	Exit	PERKINELMER INC	$0	–	-110,000	–	-4.22%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-230,000	–	-4.30%	–
LHCG	Exit	LHC GROUP INC	$0	–	-75,000	–	-4.88%	–

Q3 2020

			Value		Shares		↓ Weighting
LHCG	Sell	LHC GROUP INC	$15,942,000	-26.8%	75,000	-40.0%	4.88%	-25.3%
SAGE	Buy	SAGE THERAPEUTICS INC	$14,058,000	+73.4%	230,000	+17.9%	4.30%	+77.1%
PKI	Buy	PERKINELMER INC	$13,806,000	+369.1%	110,000	+266.7%	4.22%	+379.3%
ABT	Buy	ABBOTT LABS	$11,971,000	+161.8%	110,000	+120.0%	3.66%	+167.4%
ARNA	Sell	ARENA PHARMACEUTICALS INC	$11,219,000	+1.8%	150,000	-14.3%	3.43%	+4.0%
HUM	Buy	HUMANA INC	$10,761,000	+38.8%	26,000	+30.0%	3.29%	+41.7%
CCXI	Buy	CHEMOCENTRYX INC	$10,138,000	+17.5%	185,000	+23.3%	3.10%	+20.0%
BPMC	Sell	BLUEPRINT MEDICINES CORP	$9,734,000	+13.4%	105,000	-4.5%	2.98%	+15.9%
ABC	Buy	AMERISOURCEBERGEN CORP	$9,692,000	+6.9%	100,000	+11.1%	2.96%	+9.1%
NVRO	Sell	NEVRO CORP	$9,472,000	+5.7%	68,000	-9.3%	2.90%	+8.0%
MCK	Buy	MCKESSON CORP	$9,234,000	+140.7%	62,000	+148.0%	2.82%	+145.8%
BMRN	Buy	BIOMARIN PHARMACEUTICAL INC	$9,130,000	-7.5%	120,000	+50.0%	2.79%	-5.5%
MRK	Buy	MERCK & CO. INC	$8,295,000	+43.0%	100,000	+33.3%	2.54%	+46.1%
CRL	Sell	CHARLES RIV LABS INTL INC	$7,473,000	-22.1%	33,000	-40.0%	2.29%	-20.4%
ZBH	Buy	ZIMMER BIOMET HOLDINGS INC	$6,807,000	+62.9%	50,000	+42.9%	2.08%	+66.4%
GWPH	Sell	GW PHARMACEUTICALS PLCads	$6,328,000	-31.2%	65,000	-13.3%	1.94%	-29.8%
SNY	New	SANOFIsponsored adr	$6,271,000	–	125,000	–	1.92%	–
NVST	Buy	ENVISTA HOLDINGS CORPORATION	$6,170,000	+67.2%	250,000	+42.9%	1.89%	+70.8%
DNLI	Buy	DENALI THERAPEUTICS INC	$5,912,000	+88.1%	165,000	+26.9%	1.81%	+92.1%
CNC	New	CENTENE CORP DEL	$5,541,000	–	95,000	–	1.70%	–
EHTH	New	EHEALTH INC	$5,530,000	–	70,000	–	1.69%	–
PODD	Buy	INSULET CORP	$5,205,000	+48.8%	22,000	+22.2%	1.59%	+52.1%
MRTX	Sell	MIRATI THERAPEUTICS INC	$4,982,000	-12.7%	30,000	-40.0%	1.52%	-10.9%
NTRA	New	NATERA INC	$4,768,000	–	66,000	–	1.46%	–
CYTK	Sell	CYTOKINETICS INC	$4,330,000	-46.0%	200,000	-41.2%	1.32%	-44.8%
	New	CYTOKINETICS INCcall	$4,330,000	–	200,000	–	1.32%	–
AGIO	Sell	AGIOS PHARMACEUTICALS INC	$4,200,000	-47.6%	120,000	-20.0%	1.28%	-46.5%
BGNE	Buy	BEIGENE LTDsponsored adr	$4,153,000	+120.4%	14,500	+45.0%	1.27%	+125.2%
HALO	Buy	HALOZYME THERAPEUTICS INC	$4,073,000	+12.5%	155,000	+14.8%	1.25%	+14.9%
RETA	New	REATA PHARMACEUTICALS INCcl a	$3,897,000	–	40,000	–	1.19%	–
HOLX	New	HOLOGIC INC	$3,656,000	–	55,000	–	1.12%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$3,640,000	–	25,000	–	1.11%	–
FATE	Buy	FATE THERAPEUTICS INC	$3,397,000	+41.4%	85,000	+21.4%	1.04%	+44.5%
GH	New	GUARDANT HEALTH INC	$3,353,000	–	30,000	–	1.03%	–
GMED	New	GLOBUS MED INCcl a	$3,219,000	–	65,000	–	0.98%	–
BAX	Sell	BAXTER INTL INC	$3,217,000	-25.3%	40,000	-20.0%	0.98%	-23.7%
UHS	Sell	UNIVERSAL HLTH SVCS INCcl b	$3,211,000	-46.8%	30,000	-53.8%	0.98%	-45.7%
BMY	Sell	BRISTOL-MYERS SQUIBB CO	$3,015,000	-74.4%	50,000	-75.0%	0.92%	-73.8%
CTLT	Sell	CATALENT INC	$2,998,000	-59.1%	35,000	-65.0%	0.92%	-58.2%
PNTG	New	PENNANT GROUP INC	$2,892,000	–	75,000	–	0.88%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$2,857,000	–	12,000	–	0.87%	–
MOH	Sell	MOLINA HEALTHCARE INC	$2,746,000	-61.4%	15,000	-62.5%	0.84%	-60.6%
BHC	New	BAUSCH HEALTH COS INC	$2,720,000	–	175,000	–	0.83%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$2,715,000	–	90,000	–	0.83%	–
AKRO	New	AKERO THERAPEUTICS INC	$2,617,000	–	85,000	–	0.80%	–
ITCI	New	INTRA CELLULAR THERAPIES INC	$2,566,000	–	100,000	–	0.78%	–
KPTI	Buy	KARYOPHARM THERAPEUTICS INC	$2,555,000	+79.8%	175,000	+133.3%	0.78%	+83.3%
GOSS	Sell	GOSSAMER BIO INC	$2,482,000	-29.3%	200,000	-25.9%	0.76%	-27.8%
DXCM	Sell	DEXCOM INC	$2,473,000	-59.3%	6,000	-60.0%	0.76%	-58.5%
EW	New	EDWARDS LIFESCIENCES CORP	$2,395,000	–	30,000	–	0.73%	–
HZNP	Sell	HORIZON THERAPEUTICS PUB L	$2,330,000	-47.6%	30,000	-62.5%	0.71%	-46.4%
MGNX	Buy	MACROGENICS INC	$2,267,000	+16.0%	90,000	+28.6%	0.69%	+18.5%
ZLAB	New	ZAI LAB LTDadr	$2,079,000	–	25,000	–	0.64%	–
ACHC	New	ACADIA HEALTHCARE COMPANY IN	$2,064,000	–	70,000	–	0.63%	–
GKOS	New	GLAUKOS CORP	$1,981,000	–	40,000	–	0.61%	–
CHWY	New	CHEWY INCcl a	$1,919,000	–	35,000	–	0.59%	–
SWAV	New	SHOCKWAVE MED INC	$1,895,000	–	25,000	–	0.58%	–
DTIL	New	PRECISION BIOSCIENCES INC	$1,848,000	–	300,000	–	0.56%	–
KNSA	New	KINIKSA PHARMACEUTICALS LTD	$1,838,000	–	120,000	–	0.56%	–
GNMK	Buy	GENMARK DIAGNOSTICS INC	$1,775,000	+20.7%	125,000	+25.0%	0.54%	+23.1%
KURA	New	KURA ONCOLOGY INC	$1,532,000	–	50,000	–	0.47%	–
DRNA	Sell	DICERNA PHARMACEUTICALS INC	$1,439,000	-48.5%	80,000	-27.3%	0.44%	-47.4%
PTCT	Buy	PTC THERAPEUTICS INC	$1,407,000	-7.6%	30,100	+0.3%	0.43%	-5.7%
	New	GOSSAMER BIO INCcall	$1,241,000	–	100,000	–	0.38%	–
	New	INOVIO PHARMACEUTICALS INCput	$1,160,000	–	100,000	–	0.36%	–
GMAB	New	GENMAB A/Ssponsored ads	$1,098,000	–	30,000	–	0.34%	–
MCRB	New	SERES THERAPEUTICS INC	$849,000	–	30,000	–	0.26%	–
INSM	New	INSMED INC	$804,000	–	25,000	–	0.25%	–
CHNG	Sell	CHANGE HEALTHCARE INC	$726,000	-74.1%	50,000	-80.0%	0.22%	-73.5%
MYOV	New	MYOVANT SCIENCES LTD	$703,000	–	50,000	–	0.22%	–
ALEC	New	ALECTOR INC	$316,000	–	30,000	–	0.10%	–
BMYRT	Exit	BRISTOL-MYERS SQUIBB COright 99/99/9999	$0	–	-150,000	–	-0.16%	–
INCY	Exit	INCYTE CORP	$0	–	-10,000	–	-0.31%	–
WBA	Exit	WALGREENS BOOTS ALLIANCE INC	$0	–	-40,000	–	-0.51%	–
AMRN	Exit	AMARIN CORP PLCspons adr new	$0	–	-350,000	–	-0.72%	–
ZGNX	Exit	ZOGENIX INC	$0	–	-90,000	–	-0.73%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-20,000	–	-0.73%	–
ABBV	Exit	ABBVIE INC	$0	–	-25,000	–	-0.74%	–
	Exit	INTRA CELLULAR THERAPIES INCcall	$0	–	-100,000	–	-0.77%	–
AKBA	Exit	AKEBIA THERAPEUTICS INC	$0	–	-250,000	–	-1.02%	–
EXEL	Exit	EXELIXIS INC	$0	–	-150,000	–	-1.07%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-55,000	–	-1.43%	–
MNTA	Exit	MOMENTA PHARMACEUTICALS INC	$0	–	-150,000	–	-1.50%	–
LLY	Exit	LILLY ELI & CO	$0	–	-35,000	–	-1.72%	–
AMGN	Exit	AMGEN INC	$0	–	-25,000	–	-1.77%	–
AZN	Exit	ASTRAZENECA PLCsponsored adr	$0	–	-125,000	–	-1.98%	–
NUVA	Exit	NUVASIVE INC	$0	–	-125,000	–	-2.08%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-12,000	–	-2.24%	–
SGEN	Exit	SEATTLE GENETICS INC	$0	–	-45,000	–	-2.29%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-45,000	–	-2.38%	–
DGX	Exit	QUEST DIAGNOSTICS INC	$0	–	-120,000	–	-4.10%	–

Q2 2020

			Value		Shares		↓ Weighting
LHCG	New	LHC GROUP INC	$21,790,000	–	125,000	–	6.52%	–
DGX	New	QUEST DIAGNOSTICS INC	$13,675,000	–	120,000	–	4.10%	–
BMY	New	BRISTOL-MYERS SQUIBB CO	$11,760,000	–	200,000	–	3.52%	–
ARNA	New	ARENA PHARMACEUTICALS INC	$11,016,000	–	175,000	–	3.30%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$9,867,000	–	80,000	–	2.96%	–
CRL	New	CHARLES RIV LABS INTL INC	$9,589,000	–	55,000	–	2.87%	–
GWPH	New	GW PHARMACEUTICALS PLCads	$9,204,000	–	75,000	–	2.76%	–
ABC	New	AMERISOURCEBERGEN CORP	$9,069,000	–	90,000	–	2.72%	–
NVRO	New	NEVRO CORP	$8,960,000	–	75,000	–	2.68%	–
CCXI	New	CHEMOCENTRYX INC	$8,631,000	–	150,000	–	2.58%	–
BPMC	New	BLUEPRINT MEDICINES CORP	$8,580,000	–	110,000	–	2.57%	–
SAGE	New	SAGE THERAPEUTICS INC	$8,108,000	–	195,000	–	2.43%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$8,022,000	–	150,000	–	2.40%	–
CYTK	New	CYTOKINETICS INC	$8,014,000	–	340,000	–	2.40%	–
DHR	New	DANAHER CORPORATION	$7,957,000	–	45,000	–	2.38%	–
HUM	New	HUMANA INC	$7,755,000	–	20,000	–	2.32%	–
SGEN	New	SEATTLE GENETICS INC	$7,646,000	–	45,000	–	2.29%	–
REGN	New	REGENERON PHARMACEUTICALS	$7,484,000	–	12,000	–	2.24%	–
CTLT	New	CATALENT INC	$7,330,000	–	100,000	–	2.20%	–
MOH	New	MOLINA HEALTHCARE INC	$7,119,000	–	40,000	–	2.13%	–
NUVA	New	NUVASIVE INC	$6,958,000	–	125,000	–	2.08%	–
AZN	New	ASTRAZENECA PLCsponsored adr	$6,611,000	–	125,000	–	1.98%	–
DXCM	New	DEXCOM INC	$6,081,000	–	15,000	–	1.82%	–
UHS	New	UNIVERSAL HLTH SVCS INCcl b	$6,038,000	–	65,000	–	1.81%	–
AMGN	New	AMGEN INC	$5,897,000	–	25,000	–	1.77%	–
MRK	New	MERCK & CO. INC	$5,800,000	–	75,000	–	1.74%	–
LLY	New	LILLY ELI & CO	$5,746,000	–	35,000	–	1.72%	–
MRTX	New	MIRATI THERAPEUTICS INC	$5,709,000	–	50,000	–	1.71%	–
MNTA	New	MOMENTA PHARMACEUTICALS INC	$4,991,000	–	150,000	–	1.50%	–
EXAS	New	EXACT SCIENCES CORP	$4,782,000	–	55,000	–	1.43%	–
ABT	New	ABBOTT LABS	$4,572,000	–	50,000	–	1.37%	–
HZNP	New	HORIZON THERAPEUTICS PUB LTD	$4,446,000	–	80,000	–	1.33%	–
BAX	New	BAXTER INTL INC	$4,305,000	–	50,000	–	1.29%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$4,178,000	–	35,000	–	1.25%	–
MCK	New	MCKESSON CORP	$3,836,000	–	25,000	–	1.15%	–
NVST	New	ENVISTA HOLDINGS CORPORATION	$3,691,000	–	175,000	–	1.10%	–
HALO	New	HALOZYME THERAPEUTICS INC	$3,619,000	–	135,000	–	1.08%	–
EXEL	New	EXELIXIS INC	$3,561,000	–	150,000	–	1.07%	–
GOSS	New	GOSSAMER BIO INC	$3,510,000	–	270,000	–	1.05%	–
PODD	New	INSULET CORP	$3,497,000	–	18,000	–	1.05%	–
AKBA	New	AKEBIA THERAPEUTICS INC	$3,395,000	–	250,000	–	1.02%	–
	New	MODERNA INCput	$3,211,000	–	50,000	–	0.96%	–
DNLI	New	DENALI THERAPEUTICS INC	$3,143,000	–	130,000	–	0.94%	–
PKI	New	PERKINELMER INC	$2,943,000	–	30,000	–	0.88%	–
CHNG	New	CHANGE HEALTHCARE INC	$2,800,000	–	250,000	–	0.84%	–
DRNA	New	DICERNA PHARMACEUTICALS INC	$2,794,000	–	110,000	–	0.84%	–
	New	INTRA CELLULAR THERAPIES INCcall	$2,567,000	–	100,000	–	0.77%	–
ABBV	New	ABBVIE INC	$2,455,000	–	25,000	–	0.74%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$2,440,000	–	20,000	–	0.73%	–
ZGNX	New	ZOGENIX INC	$2,431,000	–	90,000	–	0.73%	–
AMRN	New	AMARIN CORP PLCspons adr new	$2,422,000	–	350,000	–	0.72%	–
FATE	New	FATE THERAPEUTICS INC	$2,402,000	–	70,000	–	0.72%	–
MGNX	New	MACROGENICS INC	$1,954,000	–	70,000	–	0.58%	–
BGNE	New	BEIGENE LTDsponsored adr	$1,884,000	–	10,000	–	0.56%	–
WBA	New	WALGREENS BOOTS ALLIANCE INC	$1,696,000	–	40,000	–	0.51%	–
PTCT	New	PTC THERAPEUTICS INC	$1,522,000	–	30,000	–	0.46%	–
GNMK	New	GENMARK DIAGNOSTICS INC	$1,471,000	–	100,000	–	0.44%	–
KPTI	New	KARYOPHARM THERAPEUTICS INC	$1,421,000	–	75,000	–	0.43%	–
INCY	New	INCYTE CORP	$1,040,000	–	10,000	–	0.31%	–
BMYRT	New	BRISTOL-MYERS SQUIBB COright 99/99/9999	$537,000	–	150,000	–	0.16%	–

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