MPM BioImpact LLC Activity Q4 2019-Q3 2023

Q3 2023
 Value Shares↓ Weighting
OLMA BuyOlema Pharmaceuticals, Inc.$22,942,360
+449.3%
1,857,681
+301.7%
6.12%
+628.2%
GERN BuyGeron Corporation$22,710,460
-23.0%
10,712,481
+16.6%
6.06%
+2.1%
SellMoonlake Immunotherapeutics$16,768,830
+11.4%
294,190
-0.3%
4.48%
+47.7%
IOVA BuyIovance Biotherapeutics Inc$14,957,656
-28.0%
3,287,397
+11.4%
3.99%
-4.5%
INSM SellInsmed Incorporated$13,318,315
+19.2%
527,458
-0.4%
3.56%
+57.9%
NewSTRUCTURE THERAPEUTICS INC$11,634,970230,7613.11%
RLAY SellRelay Therapeutics Inc.$11,371,439
-33.2%
1,352,133
-0.2%
3.04%
-11.4%
CBAY NewCYMABAY THERAPEUTICS INC$9,106,581610,7702.43%
KRTX SellKaruna Therapeutics Inc$8,997,279
-22.3%
53,210
-0.4%
2.40%
+3.0%
FOLD BuyAmicus Therapeutics Inc.$8,708,250
+34.3%
716,139
+38.7%
2.32%
+78.2%
BuyXeris Biopharma Holdings Inc$7,417,619
-28.8%
3,987,967
+0.3%
1.98%
-5.6%
AVDL BuyAvadel Pharmaceuticals PLC$6,841,507
+7.8%
664,224
+72.5%
1.83%
+42.9%
MDGL BuyMadrigal Pharmaceuticals inc$5,967,048
-32.0%
40,859
+7.5%
1.59%
-9.9%
KALV SellKalvista Pharmaceuticals Inc$5,565,736
-18.8%
577,958
-24.1%
1.49%
+7.7%
MORF NewMORPHIC HOLDING INC$4,582,000200,0001.22%
PHAT BuyPhathom Pharmaceuticals inc$3,601,833
-10.9%
347,332
+23.0%
0.96%
+18.2%
VKTX NewVIKING THERAPEUTICS INC$3,597,750325,0000.96%
NewHarpoon Therapeutics, Inc.$1,288,270319,6700.34%
ONCR ExitOncorus, Inc.$0-2,377,031-0.02%
ExitVentyx Biosciences Inc$0-31,747-0.21%
HARP ExitHarpoon Therapeutics, Inc.$0-3,196,707-0.46%
EWTX ExitEdgewise Therapeutics Inc$0-712,798-1.11%
RETA ExitReata Pharmaceuticals, Inc.$0-234,478-4.81%
KDNY ExitChinook Therapeutics, Inc.$0-1,003,406-7.76%
ISEE ExitIveric Bio Inc$0-1,214,662-9.62%
Q2 2023
 Value Shares↓ Weighting
CGEM NewCullinan Oncology, Inc.$82,295,3647,648,26816.57%
ISEE NewIveric Bio Inc$47,784,8031,214,6629.62%
KDNY NewChinook Therapeutics, Inc.$38,550,8591,003,4067.76%
GERN NewGeron Corporation$29,504,0419,191,2905.94%
RETA NewReata Pharmaceuticals, Inc.$23,907,377234,4784.81%
ITOS NewiTeos Therapeutics, Inc.$23,116,2851,745,9434.66%
NTLA NewIntellia Therapeutics, Inc.$22,210,378544,6394.47%
IOVA NewIovance Biotherapeutics Inc$20,768,8312,950,1184.18%
RPTX NewRepare Therapeutics, Inc.$17,349,6021,639,8493.49%
RLAY NewRelay Therapeutics Inc.$17,010,8621,354,3683.42%
VERV NewVerve Therapeutics, Inc$16,086,375857,9403.24%
NewMoonlake Immunotherapeutics$15,050,661295,1113.03%
RGNX NewREGENXBIO Inc.$13,127,793656,7182.64%
KRTX NewKaruna Therapeutics Inc$11,579,57353,3992.33%
INSM NewInsmed Incorporated$11,177,577529,7432.25%
NewXeris Biopharma Holdings Inc$10,414,4973,974,9992.10%
MDGL NewMadrigal Pharmaceuticals inc$8,780,54138,0111.77%
CRNX NewCrinetics Pharmaceuticals Inc.$8,632,535479,0531.74%
TVTX NewTravere Therapeutics Inc.$8,491,715552,8461.71%
RVMD NewRevolution Medicines, Inc.$7,313,664273,4081.47%
HOWL NewWerewolf Therapeutics, Inc.$7,283,4342,388,0111.47%
KALV NewKalvista Pharmaceuticals Inc$6,853,842761,5381.38%
AXSM NewAxsome Therapeutics, Inc.$6,725,09093,5861.35%
FOLD NewAmicus Therapeutics Inc.$6,482,706516,1391.30%
AVDL NewAvadel Pharmaceuticals PLCsponsored adr$6,344,635384,9901.28%
VRDN NewViridian Therapeutics Inc$6,074,134255,3231.22%
EWTX NewEdgewise Therapeutics Inc$5,524,185712,7981.11%
ADAP NewAdaptimmune Therapeutics plc$4,713,7195,095,9120.95%
OLMA NewOlema Pharmaceuticals, Inc.$4,176,375462,5000.84%
PHAT NewPhathom Pharmaceuticals inc$4,042,994282,3320.81%
HARP NewHarpoon Therapeutics, Inc.$2,269,6623,196,7070.46%
INZY NewInozyme Pharma Inc.$1,820,950326,9210.37%
NewVentyx Biosciences Inc$1,041,30231,7470.21%
ONCR NewOncorus, Inc.$96,2702,377,0310.02%
Q4 2022
 Value Shares↓ Weighting
BDTX ExitBlack Diamond Therapeutics, Inc.$0-239,888-0.10%
AVRO ExitAVROBIO, Inc.$0-647,918-0.10%
EPIX ExitESSA Pharma, Inc.$0-405,700-0.18%
ADCT ExitADC Therapeutics, Inc.$0-334,384-0.38%
INZY ExitInozyme Pharma Inc.$0-661,144-0.42%
ONCR ExitOncorus, Inc.$0-2,377,031-0.48%
MIRM ExitMirum Pharmaceuticals Inc.$0-97,322-0.48%
AVDL ExitAvadel Pharmaceuticals Plc$0-412,363-0.49%
PHAT ExitPhathom Pharmaceuticals Inc$0-193,326-0.51%
VSTM ExitVerastem, Inc.$0-3,244,650-0.65%
RVMD ExitRevolution Medicines, Inc.$0-146,041-0.68%
MDGL ExitMadrigal Pharmaceuticals Inc$0-44,747-0.69%
EWTX ExitEdgewise Therapeutics, Inc.$0-304,027-0.71%
HARP ExitHarpoon Therapeutics, Inc.$0-3,196,707-0.73%
PRVB ExitProvention Bio Inc$0-740,344-0.79%
FOLD ExitAmicus Therapeutics Inc.$0-392,946-0.97%
RETA ExitReata Pharmaceuticals Inc$0-179,058-1.07%
ARQT ExitArcutis Biotherapeutics inc$0-257,185-1.16%
HRMY ExitHarmony Biosciences Hldgs Inc.$0-136,780-1.44%
TCRR ExitTCR2 Therapeutics, Inc.$0-3,370,982-1.44%
YMAB ExitY Mabs Therapeutics, Inc.$0-443,702-1.52%
TVTX ExitTravere Therapeutics Inc.$0-276,460-1.61%
CRNX ExitCrinetics Pharmaceuticals Inc.$0-364,710-1.70%
BCRX ExitBiocryst Pharmaceuticals Inc.$0-605,663-1.81%
CYTK ExitCytokinetics Inc.$0-193,205-2.22%
GTHX ExitG1 Therapeutics, Inc.$0-856,798-2.53%
HOWL ExitWerewolf Therapeutics, Inc.$0-2,388,011-2.55%
IOVA ExitIovance Biotherapeutics Inc$0-1,700,000-3.86%
RGNX ExitREGENXBIO Inc.$0-619,083-3.88%
MRUS ExitMerus N.V.$0-918,310-4.36%
ISEE ExitIveric Bio Inc$0-1,050,000-4.46%
GERN ExitGeron Corporation$0-8,422,582-4.67%
RPTX ExitRepare Therapeutics, Inc.$0-1,639,849-4.71%
NTLA ExitIntellia Therapeutics, Inc.$0-374,409-4.96%
VERV ExitVerve Therapeutics, Inc$0-635,792-5.17%
INBX ExitInhibrx, Inc$0-1,279,995-5.44%
ITOS ExitiTeos Therapeutics, Inc.$0-1,745,943-7.88%
CGEM ExitCullinan Oncology, Inc.$0-7,648,268-23.22%
Q3 2022
 Value Shares↓ Weighting
INBX BuyInhibrx, Inc$22,976,000
+97.8%
1,279,995
+25.1%
5.44%
+68.7%
VERV NewVerve Therapeutics, Inc$21,839,000635,7925.17%
NTLA BuyIntellia Therapeutics, Inc.$20,952,000
+35.2%
374,409
+25.0%
4.96%
+15.3%
GERN SellGeron Corporation$19,709,000
+50.7%
8,422,582
-0.1%
4.67%
+28.5%
ISEE NewIveric Bio Inc$18,837,0001,050,0004.46%
MRUS SellMerus N.V.$18,394,000
-11.6%
918,310
-0.1%
4.36%
-24.7%
RGNX NewREGENXBIO Inc.$16,362,000619,0833.88%
IOVA BuyIovance Biotherapeutics Inc$16,286,000
+22.9%
1,700,000
+41.7%
3.86%
+4.8%
CYTK SellCytokinetics Inc.$9,361,000
+22.7%
193,205
-0.5%
2.22%
+4.6%
BCRX SellBiocryst Pharmaceuticals Inc.$7,631,000
+12.9%
605,663
-5.2%
1.81%
-3.8%
CRNX SellCrinetics Pharmaceuticals Inc.$7,163,000
+4.7%
364,710
-0.5%
1.70%
-10.7%
TVTX SellTravere Therapeutics Inc.$6,812,000
+1.1%
276,460
-0.5%
1.61%
-13.8%
HRMY SellHarmony Biosciences Hldgs Inc.$6,058,000
-9.7%
136,780
-0.5%
1.44%
-23.0%
ARQT SellArcutis Biotherapeutics inc$4,915,000
-10.8%
257,185
-0.5%
1.16%
-23.9%
RETA SellReata Pharmaceuticals Inc$4,500,000
-17.7%
179,058
-0.5%
1.07%
-29.8%
FOLD SellAmicus Therapeutics Inc.$4,102,000
-22.9%
392,946
-20.7%
0.97%
-34.3%
PRVB BuyProvention Bio Inc$3,332,000
+40.6%
740,344
+25.0%
0.79%
+19.9%
EWTX NewEdgewise Therapeutics, Inc.$2,992,000304,0270.71%
MDGL SellMadrigal Pharmaceuticals Inc$2,908,000
-9.7%
44,747
-0.6%
0.69%
-23.0%
MIRM SellMirum Pharmaceuticals Inc.$2,045,000
-63.6%
97,322
-66.3%
0.48%
-69.0%
INZY SellInozyme Pharma Inc.$1,772,000
-44.1%
661,144
-0.6%
0.42%
-52.3%
EPIX SellESSA Pharma, Inc.$738,000
-64.6%
405,700
-38.6%
0.18%
-69.7%
NEO ExitNeogenomics Inc.$0-135,573-0.31%
KRTX ExitKaruna Therapeutics inc$0-20,000-0.70%
EPZM ExitEpizyme, Inc.$0-3,425,202-1.40%
Q2 2022
 Value Shares↓ Weighting
CGEM NewCullinan Oncology, Inc.$98,051,0007,648,26827.24%
ITOS NewiTeos Therapeutics, Inc.$35,966,0001,745,9439.99%
RPTX NewRepare Therapeutics, Inc.$22,941,0001,639,8496.37%
MRUS NewMerus N.V.$20,817,000919,4825.78%
NTLA NewIntellia Therapeutics, Inc.$15,497,000299,4094.30%
IOVA NewIovance Biotherapeutics Inc Com$13,248,0001,200,0003.68%
GERN NewGeron Corporation$13,074,0008,434,9913.63%
INBX NewInhibrx, Inc.$11,615,0001,023,3253.23%
TCRR NewTCR2 Therapeutics, Inc.$9,776,0003,370,9822.72%
HOWL NewWerewolf Therapeutics, Inc.$9,767,0002,388,0112.71%
CYTK NewCytokinetics Inc.$7,632,000194,2462.12%
CRNX NewCrinetics Pharmaceuticals Inc.$6,839,000366,6761.90%
BCRX NewBiocryst Pharmaceuticals Inc.$6,762,000639,0891.88%
TVTX NewTravere Therapeutics Inc.$6,735,000277,9501.87%
YMAB NewYmAbs Therapeutics, Inc.$6,713,000443,7021.86%
HRMY NewHarmony Biosciences Hldgs Inc.$6,707,000137,5171.86%
HARP NewHarpoon Therapeutics, Inc.$6,106,0003,196,7071.70%
MIRM NewMirum Pharmaceuticals Inc.$5,615,000288,5311.56%
ARQT NewArcutis Biotherapeutics inc$5,509,000258,5001.53%
RETA NewReata Pharmaceuticals inc-a$5,470,000180,0001.52%
FOLD NewAmicus Therapeutics Inc.$5,323,000495,6031.48%
EPZM NewEpizyme, Inc.$5,035,0003,425,2021.40%
GTHX NewG1 Therapeutics, Inc.$4,233,000856,7981.18%
VSTM NewVerastem, Inc.$3,764,0003,244,6501.05%
MDGL NewMadrigal Pharmaceuticals inc$3,221,00045,0000.90%
INZY NewInozyme Pharma Inc.$3,172,000664,9800.88%
ONCR NewOncorus, Inc.$2,995,0002,377,0310.83%
RVMD NewRevolution Medicines, Inc.$2,846,000146,0410.79%
ADCT NewADC Therapeutics, Inc.$2,658,000334,3840.74%
KRTX NewKaruna Therapeutics inc$2,530,00020,0000.70%
PRVB NewProvention Bio Inc$2,370,000592,4350.66%
EPIX NewESSA Pharma, Inc.$2,082,000660,8920.58%
PHAT NewPhathom Pharmaceuticals inc$1,632,000193,3260.45%
NEO NewNeogenomics Inc.$1,105,000135,5730.31%
AVDL NewAvadel Pharmaceuticals Plcadr$1,006,000412,3630.28%
AVRO NewAVROBIO, Inc.$596,000647,9180.17%
BDTX NewBlack Diamond Therapeutics, Inc.$590,000239,8880.16%
Q4 2021
 Value Shares↓ Weighting
BDTX ExitBlack Diamond Therapeutics, Inc.$0-248,506-0.33%
AXSM ExitAxsome Therapeutics Inc.$0-110,155-0.56%
INZY ExitInozyme Pharma Inc.$0-320,724-0.58%
AVDL ExitAvadel Pharmaceuticals Plc$0-400,000-0.61%
RVMD ExitRevolution Medicines, Inc.$0-150,000-0.64%
LHDX ExitLucira Health Inc.$0-578,114-0.68%
AVRO ExitAVROBIO, Inc.$0-861,858-0.75%
FOLD ExitAmicus Therapeutics Inc.$0-546,558-0.81%
EPIX ExitESSA Pharma, Inc.$0-683,287-0.85%
HRMY ExitHarmony Biosciences Hldgs Inc.$0-151,650-0.90%
MIRM ExitMirum Pharmaceuticals Inc.$0-308,532-0.95%
CRNX ExitCrinetics Pharmaceuticals Inc.$0-298,392-0.97%
NEO ExitNeogenomics Inc.$0-149,504-1.12%
TVTX ExitTravere Therapeutics Inc.$0-306,515-1.15%
GERN ExitGeron Corporation$0-5,732,770-1.22%
VSTM ExitVerastem, Inc.$0-2,824,857-1.35%
CYTK ExitCytokinetics Inc.$0-247,291-1.37%
ADCT ExitADC Therapeutics, Inc.$0-344,519-1.45%
BCRX ExitBiocryst Pharmaceuticals Inc.$0-704,767-1.57%
GTHX ExitG1 Therapeutics, Inc.$0-860,502-1.79%
YMAB ExitYmAbs Therapeutics, Inc.$0-452,970-2.00%
TPTX ExitTurning Point Therapeutics, Inc.$0-271,350-2.80%
EPZM ExitEpizyme, Inc.$0-3,972,830-3.16%
MRUS ExitMerus N.V.$0-941,948-3.21%
NTLA ExitIntellia Therapeutics, Inc.$0-162,620-3.38%
ONCR ExitOncorus, Inc.$0-2,377,031-3.44%
HARP ExitHarpoon Therapeutics, Inc.$0-3,196,707-3.92%
TCRR ExitTCR2 Therapeutics, Inc.$0-3,370,982-4.45%
ExitMEI Pharma, Inc.$0-12,494,118-5.35%
HOWL ExitWerewolf Therapeutics, Inc.$0-2,388,011-6.36%
RPTX ExitRepare Therapeutics, Inc.$0-1,639,849-6.68%
ITOS ExitiTeos Therapeutics, Inc.$0-2,107,092-8.82%
CGEM ExitCullinan Oncology, Inc.$0-7,648,268-26.78%
Q3 2021
 Value Shares↓ Weighting
CGEM SellCullinan Oncology, Inc.$172,621,000
-15.3%
7,648,268
-3.4%
26.78%
-20.0%
ITOS SelliTeos Therapeutics, Inc.$56,891,000
-5.2%
2,107,092
-9.9%
8.82%
-10.4%
RPTX SellRepare Therapeutics, Inc.$43,030,000
-17.7%
1,639,849
-2.2%
6.68%
-22.2%
BuyMEI Pharma, Inc.$34,484,000
+19.4%
12,494,118
+23.2%
5.35%
+12.7%
NTLA NewIntellia Therapeutics, Inc.$21,815,000162,6203.38%
MRUS BuyMerus N.V.$20,723,000
+40.3%
941,948
+34.4%
3.21%
+32.5%
EPZM BuyEpizyme, Inc.$20,341,000
+5.0%
3,972,830
+70.4%
3.16%
-0.9%
TPTX BuyTurning Point Therapeutics, Inc.$18,026,000
-14.2%
271,350
+0.8%
2.80%
-19.0%
YMAB BuyYmAbs Therapeutics, Inc.$12,928,000
+13.4%
452,970
+34.3%
2.00%
+7.0%
GTHX BuyG1 Therapeutics, Inc.$11,548,000
-35.2%
860,502
+5.9%
1.79%
-38.9%
BCRX NewBiocryst Pharmaceuticals Inc.$10,128,000704,7671.57%
ADCT BuyADC Therapeutics, Inc.$9,357,000
+76.2%
344,519
+58.0%
1.45%
+66.4%
CYTK NewCytokinetics Inc.$8,838,000247,2911.37%
VSTM NewVerastem, Inc.$8,701,0002,824,8571.35%
GERN NewGeron Corporation$7,854,0005,732,7701.22%
TVTX NewTravere Therapeutics Inc.$7,433,000306,5151.15%
NEO NewNeogenomics Inc.$7,212,000149,5041.12%
CRNX NewCrinetics Pharmaceuticals Inc.$6,281,000298,3920.97%
MIRM NewMirum Pharmaceuticals Inc.$6,146,000308,5320.95%
HRMY NewHarmony Biosciences Hldgs Inc.$5,813,000151,6500.90%
EPIX NewESSA Pharma, Inc.$5,466,000683,2870.85%
FOLD NewAmicus Therapeutics Inc.$5,220,000546,5580.81%
AVRO NewAVROBIO, Inc.$4,809,000861,8580.75%
LHDX NewLucira Health Inc.$4,394,000578,1140.68%
RVMD NewRevolution Medicines, Inc.$4,127,000150,0000.64%
AVDL NewAvadel Pharmaceuticals Plc$3,920,000400,0000.61%
INZY NewInozyme Pharma Inc.$3,717,000320,7240.58%
AXSM NewAxsome Therapeutics Inc.$3,631,000110,1550.56%
BDTX NewBlack Diamond Therapeutics, Inc.$2,102,000248,5060.33%
Q2 2021
 Value Shares↓ Weighting
CGEM NewCullinan Management, Inc.$203,783,0007,913,88733.48%
ITOS NewiTeos Therapeutics, Inc.$59,985,0002,338,5819.85%
TCRR NewTCR2 Therapeutics, Inc.$55,318,0003,370,9829.09%
RPTX NewRepare Therapeutics, Inc.$52,260,0001,676,0878.58%
HARP NewHarpoon Therapeutics, Inc.$44,338,0003,196,7077.28%
HOWL NewWerewolf Therapeutics, Inc.$41,647,0002,388,0116.84%
ONCR NewOncorus, Inc.$32,803,0002,377,0315.39%
NewMEI Pharma, Inc.$28,893,00010,137,8594.75%
TPTX NewTurning Point Therapeutics, Inc.$21,002,000269,1863.45%
EPZM NewEpizyme, Inc.$19,375,0002,331,5343.18%
GTHX NewG1 Therapeutics, Inc.$17,833,000812,7942.93%
MRUS NewMerus N.V.$14,768,000700,8792.43%
YMAB NewYmAbs Therapeutics, Inc.$11,400,000337,2911.87%
ADCT NewADC Therapeutics, Inc.$5,309,000218,0270.87%
Q4 2020
 Value Shares↓ Weighting
AUTL ExitAutolus Therapeutics Limited$0-39,740-0.11%
MRUS ExitMerus N.V.$0-700,879-2.03%
YMAB ExitYmAbs Therapeutics, Inc.$0-337,291-3.12%
GTHX ExitG1 Therapeutics, Inc.$0-1,423,794-3.96%
ADCT ExitADC Therapeutics, Inc.$0-539,648-4.29%
TPTX ExitTurning Point Therapeutics, Inc.$0-308,686-6.50%
ExitMEI Pharma, Inc.$0-10,137,859-7.62%
EPZM ExitEpizyme, Inc.$0-2,854,737-8.20%
ITOS ExitiTeos Therapeutics, Inc.$0-2,355,557-14.00%
HARP ExitHarpoon Therapeutics, Inc.$0-3,898,422-15.96%
TCRR ExitTCR2 Therapeutics, Inc.$0-3,370,982-16.50%
RPTX ExitRepare Therapeutics, Inc.$0-2,388,337-17.71%
Q3 2020
 Value Shares↓ Weighting
ITOS NewiTeos Therapeutics, Inc.$58,112,0002,355,55714.00%
EPZM BuyEpizyme, Inc.$34,057,000
-9.0%
2,854,737
+22.4%
8.20%
-17.6%
Q2 2020
 Value Shares↓ Weighting
RPTX NewRepare Therapeutics, Inc.$74,086,0002,388,33719.70%
HARP NewHarpoon Therapeutics, Inc.$64,714,0003,898,42217.21%
TCRR NewTCR2 Therapeutics, Inc.$51,778,0003,370,98213.77%
NewMEI Pharma, Inc.$41,869,00010,137,85911.13%
EPZM NewEpizyme, Inc.$37,444,0002,331,5349.96%
GTHX NewG1 Therapeutics, Inc.$34,541,0001,423,7949.18%
ADCT NewADC Therapeutics, Inc.$25,261,000539,6486.72%
TPTX NewTurning Point Therapeutics, Inc.$19,938,000308,6865.30%
YMAB NewYmAbs Therapeutics, Inc.$14,571,000337,2913.87%
MRUS NewMerus N.V.$11,277,000700,8793.00%
AUTL NewAutolus Therapeutics Limited$637,00039,7400.17%

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