Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | Soleno Therapeutics Inc | $94,523,274 | – | 3,203,093 | – | 10.36% | – | |
| AVDL | Buy | Avadel Pharmaceuticals PLCadr | $42,193,208 | -33.1% | 4,096,428 | +7.0% | 4.62% | +6.1% |
| GRCL | Buy | Gracell Biotechnologies Incsponsored ads | $31,337,695 | +107.2% | 10,881,144 | +174.1% | 3.43% | +228.8% |
| OLMA | Buy | Olema Pharmaceuticals Inc | $23,140,244 | +91.3% | 1,873,704 | +39.9% | 2.54% | +203.6% |
| Buy | Arcellx Inc. | $18,067,912 | +31.7% | 503,565 | +16.1% | 1.98% | +109.0% | |
| New | Rayzebio Inc | $14,065,387 | – | 633,576 | – | 1.54% | – | |
| CMPS | New | Compass Pathway PLCsponsored ads | $11,899,200 | – | 1,608,000 | – | 1.30% | – |
| ZLAB | Buy | Zai Lab Ltd ADRadr | $11,051,472 | -10.5% | 454,606 | +2.0% | 1.21% | +42.0% |
| CRNX | New | Crinetics Pharmaceuticals Inc | $10,409,000 | – | 350,000 | – | 1.14% | – |
| DYN | Buy | Dyne Therapeutics Inc | $9,274,819 | +42.7% | 1,035,136 | +79.2% | 1.02% | +126.3% |
| Buy | IO Biotech Inc | $8,704,549 | +47.7% | 6,173,439 | +104.7% | 0.95% | +134.4% | |
| New | Apogee Therapeutics Inc | $8,520,000 | – | 400,000 | – | 0.93% | – | |
| DCTH | Buy | Delcath Systems, Inc. | $7,513,524 | +9.3% | 1,855,191 | +57.4% | 0.82% | +73.6% |
| SVRA | New | Savara Inc | $7,232,459 | – | 1,913,349 | – | 0.79% | – |
| ORIC | New | Oric Pharmaceuticals Inc | $4,706,561 | – | 777,944 | – | 0.52% | – |
| New | Unicycive Therapeutics | $2,984,331 | – | 3,470,152 | – | 0.33% | – | |
| FULC | Sell | Fulcrum Therapeutics Inc | $2,308,800 | +27.2% | 520,000 | -5.5% | 0.25% | +102.4% |
| CLNN | Sell | Clene Inc | $1,396,738 | -62.3% | 2,645,338 | -41.5% | 0.15% | -40.2% |
| ASLN | Sell | Aslan Pharmaceuticals Ltdads | $1,068,181 | -89.7% | 568,182 | -80.0% | 0.12% | -83.7% |
| BCAB | Sell | BioAtla Inc | $908,108 | -52.5% | 534,181 | -16.2% | 0.10% | -25.0% |
| RZLT | Sell | Rezolute Inc | $639,459 | -34.0% | 484,439 | -1.0% | 0.07% | +4.5% |
| IMUX | Exit | Immunic Inc | $0 | – | -632,184 | – | -0.11% | – |
| KDNY | Exit | Chinook Therapeutics Inc | $0 | – | -934,879 | – | -2.48% | – |
| VECT | Exit | VectivBio Holding AG | $0 | – | -2,333,300 | – | -2.72% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SVA | New | Sinovac Biotech Ltd. | $615,369,410 | – | 5,900,000 | – | 42.48% | – |
| HRMY | New | Harmony Biosciences Holdings Inc | $91,713,832 | – | 2,606,247 | – | 6.33% | – |
| VRNA | New | Verona Pharma PLCads | $89,843,267 | – | 4,249,918 | – | 6.20% | – |
| AVDL | New | Avadel Pharmaceuticals PLCadr | $63,111,429 | – | 3,829,577 | – | 4.36% | – |
| TERN | New | Terns Pharmaceuticals Inc | $58,257,430 | – | 6,657,992 | – | 4.02% | – |
| GERN | New | Geron Corp | $53,044,075 | – | 16,524,634 | – | 3.66% | – |
| TARS | New | Tarsus Pharmaceuticals Inc | $40,877,954 | – | 2,262,200 | – | 2.82% | – |
| VRDN | New | Viridian Therapeutics Inc | $39,924,545 | – | 1,678,207 | – | 2.76% | – |
| VECT | New | VectivBio Holding AG | $39,362,771 | – | 2,333,300 | – | 2.72% | – |
| KDNY | New | Chinook Therapeutics Inc | $35,918,051 | – | 934,879 | – | 2.48% | – |
| ALXO | New | ALX Oncology Holdings Inc | $31,692,560 | – | 4,220,048 | – | 2.19% | – |
| COGT | New | Cogent Biosciences Inc | $26,580,101 | – | 2,244,941 | – | 1.84% | – |
| New | Icosavax, Inc. | $16,926,360 | – | 1,704,568 | – | 1.17% | – | |
| GRCL | New | Gracell Biotechnologies Incsponsored ads | $15,123,517 | – | 3,969,427 | – | 1.04% | – |
| New | Astria Therapeutics Inc | $14,004,388 | – | 1,681,199 | – | 0.97% | – | |
| New | Ventyx Biosciences Inc | $13,844,060 | – | 422,075 | – | 0.96% | – | |
| New | Arcellx Inc. | $13,716,282 | – | 433,785 | – | 0.95% | – | |
| ALLK | New | Allakos Inc | $13,027,680 | – | 2,988,000 | – | 0.90% | – |
| ZLAB | New | Zai Lab Ltd ADRadr | $12,353,854 | – | 445,505 | – | 0.85% | – |
| OLMA | New | Olema Pharmaceuticals Inc | $12,093,617 | – | 1,339,271 | – | 0.84% | – |
| New | Verastem Inc | $11,446,150 | – | 1,538,461 | – | 0.79% | – | |
| CMPX | New | Compass Therapeutics Inc | $11,308,153 | – | 3,556,023 | – | 0.78% | – |
| ASLN | New | Aslan Pharmaceuticals Ltdads | $10,369,314 | – | 2,840,908 | – | 0.72% | – |
| ALPN | New | Alpine Immune Sciences Inc | $9,405,306 | – | 914,913 | – | 0.65% | – |
| ACRS | New | Aclaris Therapeutics, Inc. | $9,318,803 | – | 898,631 | – | 0.64% | – |
| AMRS | New | Amyris, Inc | $7,983,353 | – | 7,750,828 | – | 0.55% | – |
| KALV | New | KalVista Pharmaceuticals Inc. | $7,704,072 | – | 856,008 | – | 0.53% | – |
| GTH | New | Genetron Holdings Ltdads | $7,556,294 | – | 8,124,174 | – | 0.52% | – |
| TIL | New | Instil Bio Inc | $6,880,220 | – | 12,486,787 | – | 0.48% | – |
| DCTH | New | Delcath Systems, Inc. | $6,872,328 | – | 1,178,787 | – | 0.47% | – |
| DYN | New | Dyne Therapeutics Inc | $6,498,473 | – | 577,642 | – | 0.45% | – |
| New | Aadi Bioscience Inc | $6,456,277 | – | 509,572 | – | 0.45% | – | |
| New | Sera Prognostics Inc | $6,115,556 | – | 1,856,011 | – | 0.42% | – | |
| New | IO Biotech Inc | $5,895,390 | – | 3,015,545 | – | 0.41% | – | |
| DBVT | New | DBV Technologies SAsponsored adr | $5,146,863 | – | 2,708,875 | – | 0.36% | – |
| BOLT | New | Bolt Therapeutics Inc | $4,955,252 | – | 3,871,291 | – | 0.34% | – |
| ARWR | New | Arrowhead Pharmaceuticals Inc | $4,900,076 | – | 137,411 | – | 0.34% | – |
| IOVA | New | Iovance Biotherapeutics Inc | $4,611,601 | – | 655,057 | – | 0.32% | – |
| CLNN | New | Clene Inc | $3,706,910 | – | 4,520,622 | – | 0.26% | – |
| IMPL | New | Impel NeuroPharma Inc | $3,663,682 | – | 2,884,789 | – | 0.25% | – |
| ALGS | New | Aligos Therapeutics Inc | $3,444,166 | – | 3,547,030 | – | 0.24% | – |
| BCAB | New | BioAtla Inc | $1,911,543 | – | 637,181 | – | 0.13% | – |
| FULC | New | Fulcrum Therapeutics Inc | $1,815,000 | – | 550,000 | – | 0.12% | – |
| IMUX | New | Immunic Inc | $1,586,782 | – | 632,184 | – | 0.11% | – |
| CDXS | New | Codexis, Inc | $1,086,803 | – | 388,144 | – | 0.08% | – |
| RZLT | New | Rezolute Inc | $969,157 | – | 489,473 | – | 0.07% | – |
| FIXX | New | Homology Medicines, Inc. | $327,510 | – | 370,068 | – | 0.02% | – |
| DTIL | New | Precision Biosciences Inc | $73,774 | – | 140,255 | – | 0.01% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MTCR | Exit | Metacrine Inc | $0 | – | -146,426 | – | -0.01% | – |
| DTIL | Exit | Precision Biosciences Inc | $0 | – | -140,255 | – | -0.02% | – |
| FIXX | Exit | Homology Medicines, Inc. | $0 | – | -370,068 | – | -0.07% | – |
| RZLT | Exit | Rezolute Inc | $0 | – | -489,473 | – | -0.15% | – |
| ASLN | Exit | Aslan Pharmaceuticals Ltdads | $0 | – | -2,840,909 | – | -0.19% | – |
| Exit | Minerva Surgical Inc | $0 | – | -2,215,667 | – | -0.20% | – | |
| CDXS | Exit | Codexis, Inc | $0 | – | -388,144 | – | -0.26% | – |
| Exit | Sera Prognostics Inc | $0 | – | -1,856,011 | – | -0.33% | – | |
| GRCL | Exit | Gracell Biotechnologies Incsponsored ads | $0 | – | -961,359 | – | -0.34% | – |
| ALGS | Exit | Aligos Therapeutics Inc | $0 | – | -3,547,030 | – | -0.43% | – |
| ARWR | Exit | Arrowhead Pharmaceuticals Inc | $0 | – | -137,411 | – | -0.50% | – |
| CMPX | Exit | Compass Therapeutics Inc | $0 | – | -2,000,000 | – | -0.50% | – |
| OLMA | Exit | Olema Pharmaceuticals Inc | $0 | – | -1,689,515 | – | -0.52% | – |
| DBVT | Exit | DBV Technologies SAsponsored adr | $0 | – | -2,708,875 | – | -0.53% | – |
| CLDX | Exit | Celldex Therapeutics Inc | $0 | – | -198,983 | – | -0.62% | – |
| BOLT | Exit | Bolt Therapeutics Inc | $0 | – | -3,871,291 | – | -0.63% | – |
| IOVA | Exit | Iovance Biotherapeutics Inc | $0 | – | -655,057 | – | -0.69% | – |
| GTH | Exit | Genetron Holdings Ltdads | $0 | – | -8,124,174 | – | -0.70% | – |
| Exit | Aadi Bioscience Inc | $0 | – | -509,572 | – | -0.80% | – | |
| DYN | Exit | Dyne Therapeutics Inc | $0 | – | -577,642 | – | -0.81% | – |
| STSA | Exit | Satsuma Pharmaceuticals Inc | $0 | – | -1,232,394 | – | -0.82% | – |
| Exit | IO Biotech Inc | $0 | – | -3,015,545 | – | -0.90% | – | |
| ISEE | Exit | Iveric Bio Inc | $0 | – | -483,413 | – | -0.96% | – |
| MRUS | Exit | Merus NV | $0 | – | -442,000 | – | -0.98% | – |
| Exit | Astria Therapeutics Inc | $0 | – | -1,000,000 | – | -1.00% | – | |
| ZLAB | Exit | Zai Lab Ltd ADRadr | $0 | – | -271,528 | – | -1.02% | – |
| PCVX | Exit | Vaxcyte Inc | $0 | – | -404,508 | – | -1.07% | – |
| LEGN | Exit | Legend Biotech Corp Sponsoredsponsored ads | $0 | – | -244,375 | – | -1.10% | – |
| BLU | Exit | Bellus Health Inc | $0 | – | -1,017,152 | – | -1.19% | – |
| Exit | Cincor Pharma Inc | $0 | – | -349,237 | – | -1.26% | – | |
| IMPL | Exit | Impel NeuroPharma Inc | $0 | – | -2,884,789 | – | -1.55% | – |
| ACRS | Exit | Aclaris Therapeutics, Inc. | $0 | – | -898,631 | – | -1.56% | – |
| VERA | Exit | Vera Therapeutics Inc | $0 | – | -666,666 | – | -1.57% | – |
| AVDL | Exit | Avadel Pharmaceuticals PLCadr | $0 | – | -2,937,093 | – | -1.62% | – |
| ASND | Exit | Ascendis Pharma A/Ssponsored adr | $0 | – | -146,025 | – | -1.66% | – |
| KDNY | Exit | Chinook Therapeutics Inc | $0 | – | -872,151 | – | -1.89% | – |
| KALV | Exit | KalVista Pharmaceuticals Inc. | $0 | – | -1,533,559 | – | -2.46% | – |
| AMRS | Exit | Amyris, Inc | $0 | – | -7,750,828 | – | -2.50% | – |
| ALLK | Exit | Allakos Inc | $0 | – | -4,120,134 | – | -2.78% | – |
| RLMD | Exit | Relmada Therapeutics Inc | $0 | – | -713,238 | – | -2.92% | – |
| COGT | Exit | Cogent Biosciences Inc | $0 | – | -1,883,941 | – | -3.10% | – |
| VRDN | Exit | Viridian Therapeutics Inc | $0 | – | -1,660,019 | – | -3.76% | – |
| TERN | Exit | Terns Pharmaceuticals Inc | $0 | – | -5,899,372 | – | -3.84% | – |
| GERN | Exit | Geron Corp | $0 | – | -15,238,095 | – | -3.94% | – |
| SVA | Exit | Sinovac Biotech Ltd. | $0 | – | -5,900,000 | – | -4.21% | – |
| TARS | Exit | Tarsus Pharmaceuticals Inc | $0 | – | -2,262,200 | – | -4.28% | – |
| ALXO | Exit | ALX Oncology Holdings Inc | $0 | – | -4,220,048 | – | -4.46% | – |
| VRNA | Exit | Verona Pharma PLCads | $0 | – | -4,249,918 | – | -4.80% | – |
| Exit | Ventyx Biosciences Inc | $0 | – | -1,355,861 | – | -5.23% | – | |
| TIL | Exit | Instil Bio Inc | $0 | – | -12,486,787 | – | -6.67% | – |
| HRMY | Exit | Harmony Biosciences Holdings Inc | $0 | – | -3,400,261 | – | -16.63% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HRMY | Sell | Harmony Biosciences Holdings Inc | $150,598,000 | -24.6% | 3,400,261 | -16.9% | 16.63% | -17.1% |
| Sell | Ventyx Biosciences Inc | $47,333,000 | +101.4% | 1,355,861 | -29.4% | 5.23% | +121.4% | |
| VRNA | Buy | Verona Pharma PLCads | $43,434,000 | +277.0% | 4,249,918 | +54.5% | 4.80% | +314.4% |
| TARS | Sell | Tarsus Pharmaceuticals Inc | $38,729,000 | +14.7% | 2,262,200 | -2.2% | 4.28% | +26.1% |
| TERN | Buy | Terns Pharmaceuticals Inc | $34,747,000 | +423.8% | 5,899,372 | +120.5% | 3.84% | +476.0% |
| VRDN | Buy | Viridian Therapeutics Inc | $34,047,000 | +126.4% | 1,660,019 | +27.7% | 3.76% | +148.9% |
| COGT | Sell | Cogent Biosciences Inc | $28,108,000 | +62.2% | 1,883,941 | -1.9% | 3.10% | +78.3% |
| RLMD | Buy | Relmada Therapeutics Inc | $26,404,000 | +97.0% | 713,238 | +1.0% | 2.92% | +116.6% |
| ALLK | New | Allakos Inc | $25,215,000 | – | 4,120,134 | – | 2.78% | – |
| AMRS | Sell | Amyris, Inc | $22,632,000 | +5.1% | 7,750,828 | -33.4% | 2.50% | +15.5% |
| New | Cincor Pharma Inc | $11,462,000 | – | 349,237 | – | 1.26% | – | |
| PCVX | New | Vaxcyte Inc | $9,708,000 | – | 404,508 | – | 1.07% | – |
| New | Astria Therapeutics Inc | $9,040,000 | – | 1,000,000 | – | 1.00% | – | |
| ISEE | Sell | Iveric Bio Inc | $8,672,000 | -82.8% | 483,413 | -90.8% | 0.96% | -81.1% |
| CLDX | Sell | Celldex Therapeutics Inc | $5,593,000 | -62.9% | 198,983 | -64.4% | 0.62% | -59.2% |
| DBVT | New | DBV Technologies SAsponsored adr | $4,795,000 | – | 2,708,875 | – | 0.53% | – |
| ZYME | Exit | Zymeworks Inc | $0 | – | -286,064 | – | -0.15% | – |
| DSGN | Exit | Design Therapeutics | $0 | – | -476,589 | – | -0.67% | – |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -3,329,509 | – | -18.38% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HRMY | New | Harmony Biosciences Holdings Inc | $199,654,000 | – | 4,093,785 | – | 20.05% | – |
| SRRA | New | Sierra Oncology, Inc | $183,090,000 | – | 3,329,509 | – | 18.38% | – |
| TIL | New | Instil Bio Inc | $57,689,000 | – | 12,486,787 | – | 5.79% | – |
| ISEE | New | Iveric Bio Inc | $50,396,000 | – | 5,238,634 | – | 5.06% | – |
| SVA | New | Sinovac Biotech Ltd. | $38,173,000 | – | 5,900,000 | – | 3.83% | – |
| ALXO | New | ALX Oncology Holdings Inc | $34,140,000 | – | 4,220,048 | – | 3.43% | – |
| TARS | New | Tarsus Pharmaceuticals Inc | $33,761,000 | – | 2,312,368 | – | 3.39% | – |
| IMPL | New | Impel NeuroPharma Inc | $26,886,000 | – | 2,884,789 | – | 2.70% | – |
| GERN | New | Geron Corp | $23,619,000 | – | 15,238,095 | – | 2.37% | – |
| New | Ventyx Biosciences Inc | $23,503,000 | – | 1,921,726 | – | 2.36% | – | |
| AMRS | New | Amyris, Inc | $21,538,000 | – | 11,642,195 | – | 2.16% | – |
| COGT | New | Cogent Biosciences Inc | $17,327,000 | – | 1,920,941 | – | 1.74% | – |
| KDNY | New | Chinook Therapeutics Inc | $15,254,000 | – | 872,151 | – | 1.53% | – |
| KALV | New | KalVista Pharmaceuticals Inc. | $15,090,000 | – | 1,533,559 | – | 1.52% | – |
| CLDX | New | Celldex Therapeutics Inc | $15,061,000 | – | 558,636 | – | 1.51% | – |
| VRDN | New | Viridian Therapeutics Inc | $15,041,000 | – | 1,300,000 | – | 1.51% | – |
| New | IO Biotech Inc | $14,083,000 | – | 3,015,545 | – | 1.41% | – | |
| GTH | New | Genetron Holdings Ltdads | $13,811,000 | – | 8,124,174 | – | 1.39% | – |
| ASND | New | Ascendis Pharma A/Ssponsored adr | $13,574,000 | – | 146,025 | – | 1.36% | – |
| LEGN | New | Legend Biotech Corp Sponsoredsponsored ads | $13,441,000 | – | 244,375 | – | 1.35% | – |
| RLMD | New | Relmada Therapeutics Inc | $13,405,000 | – | 705,882 | – | 1.35% | – |
| ACRS | New | Aclaris Therapeutics, Inc. | $12,545,000 | – | 898,631 | – | 1.26% | – |
| VRNA | New | Verona Pharma PLCads | $11,522,000 | – | 2,749,918 | – | 1.16% | – |
| MRUS | New | Merus NV | $10,007,000 | – | 442,000 | – | 1.00% | – |
| ZLAB | New | Zai Lab Ltd ADRadr | $9,417,000 | – | 271,528 | – | 0.95% | – |
| BLU | New | Bellus Health Inc | $9,398,000 | – | 1,017,152 | – | 0.94% | – |
| VERA | New | Vera Therapeutics Inc | $9,073,000 | – | 666,666 | – | 0.91% | – |
| BOLT | New | Bolt Therapeutics Inc | $7,897,000 | – | 3,871,291 | – | 0.79% | – |
| IOVA | New | Iovance Biotherapeutics Inc | $7,232,000 | – | 655,057 | – | 0.73% | – |
| AVDL | New | Avadel Pharmaceuticals PLCadr | $7,167,000 | – | 2,937,093 | – | 0.72% | – |
| OLMA | New | Olema Pharmaceuticals Inc | $6,876,000 | – | 1,689,515 | – | 0.69% | – |
| DSGN | New | Design Therapeutics | $6,672,000 | – | 476,589 | – | 0.67% | – |
| TERN | New | Terns Pharmaceuticals Inc | $6,634,000 | – | 2,675,133 | – | 0.67% | – |
| New | Aadi Bioscience Inc | $6,278,000 | – | 509,572 | – | 0.63% | – | |
| CMPX | New | Compass Therapeutics Inc | $5,300,000 | – | 2,000,000 | – | 0.53% | – |
| GRCL | New | Gracell Biotechnologies Incsponsored ads | $5,287,000 | – | 961,359 | – | 0.53% | – |
| New | Minerva Surgical Inc | $5,207,000 | – | 2,215,667 | – | 0.52% | – | |
| STSA | New | Satsuma Pharmaceuticals Inc | $5,102,000 | – | 1,232,394 | – | 0.51% | – |
| ARWR | New | Arrowhead Pharmaceuticals Inc | $4,838,000 | – | 137,411 | – | 0.49% | – |
| ALGS | New | Aligos Therapeutics Inc | $4,292,000 | – | 3,547,030 | – | 0.43% | – |
| CDXS | New | Codexis, Inc | $4,060,000 | – | 388,144 | – | 0.41% | – |
| DYN | New | Dyne Therapeutics Inc | $3,968,000 | – | 577,642 | – | 0.40% | – |
| New | Sera Prognostics Inc | $3,044,000 | – | 1,856,011 | – | 0.31% | – | |
| RZLT | New | Rezolute Inc | $1,581,000 | – | 489,473 | – | 0.16% | – |
| ZYME | New | Zymeworks Inc | $1,516,000 | – | 286,064 | – | 0.15% | – |
| ASLN | New | Aslan Pharmaceuticals Ltdads | $1,406,000 | – | 2,840,909 | – | 0.14% | – |
| FIXX | New | Homology Medicines, Inc. | $729,000 | – | 370,068 | – | 0.07% | – |
| DTIL | New | Precision Biosciences Inc | $224,000 | – | 140,255 | – | 0.02% | – |
| MTCR | New | Metacrine Inc | $73,000 | – | 146,426 | – | 0.01% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MTCR | Exit | Metacrine Inc | $0 | – | -146,426 | – | -0.02% | – |
| TCDA | Exit | Tricida, Inc. | $0 | – | -167,863 | – | -0.04% | – |
| ZGNX | Exit | Zogenix Inc | $0 | – | -105,000 | – | -0.07% | – |
| DTIL | Exit | Precision Biosciences Inc | $0 | – | -140,255 | – | -0.07% | – |
| TXG | Exit | 10X Genomics Inc | $0 | – | -14,798 | – | -0.10% | – |
| ORTX | Exit | Orchard Therapeutics plcads | $0 | – | -1,325,736 | – | -0.14% | – |
| EIGR | Exit | Eiger BioPharmaceuticals Inc | $0 | – | -469,588 | – | -0.14% | – |
| ELEV | Exit | Elevation Oncology Inc | $0 | – | -496,843 | – | -0.17% | – |
| LRMR | Exit | Larimar Therapeutics Inc | $0 | – | -399,830 | – | -0.21% | – |
| ASLN | Exit | Aslan Pharmaceuticals Ltdads | $0 | – | -2,840,909 | – | -0.23% | – |
| PASG | Exit | Passage Bio Inc | $0 | – | -539,263 | – | -0.24% | – |
| STSA | Exit | Satsuma Pharmaceuticals Inc | $0 | – | -1,232,394 | – | -0.26% | – |
| SNDX | Exit | Syndax Pharmaceuticals Inc | $0 | – | -320,000 | – | -0.28% | – |
| VALN | Exit | Valneva SEsponsored ads | $0 | – | -200,000 | – | -0.28% | – |
| FIXX | Exit | Homology Medicines, Inc. | $0 | – | -853,143 | – | -0.30% | – |
| DSGN | Exit | Design Therapeutics | $0 | – | -530,991 | – | -0.35% | – |
| ZYME | Exit | Zymeworks Inc | $0 | – | -286,064 | – | -0.37% | – |
| EPIX | Exit | Essa Pharma Inc | $0 | – | -1,056,067 | – | -0.38% | – |
| ARWR | Exit | Arrowhead Pharmaceuticals Inc | $0 | – | -137,411 | – | -0.38% | – |
| CDXS | Exit | Codexis, Inc | $0 | – | -388,144 | – | -0.40% | – |
| DYN | Exit | Dyne Therapeutics Inc | $0 | – | -577,642 | – | -0.42% | – |
| MRUS | Exit | Merus NV | $0 | – | -442,000 | – | -0.44% | – |
| KURA | Exit | Kura Oncology Inc | $0 | – | -525,262 | – | -0.44% | – |
| ARQT | Exit | Arcutis Biotherapeutics Inc | $0 | – | -433,585 | – | -0.46% | – |
| CRNX | Exit | Crinetics Pharmaceuticals Inc | $0 | – | -517,280 | – | -0.49% | – |
| AUPH | Exit | Aurinia Pharmaceuticals Inc. | $0 | – | -500,732 | – | -0.50% | – |
| KDNY | Exit | Chinook Therapeutics Inc | $0 | – | -872,151 | – | -0.50% | – |
| COGT | Exit | Cogent Biosciences Inc | $0 | – | -1,420,941 | – | -0.54% | – |
| CRIS | Exit | Curis Inc | $0 | – | -1,553,500 | – | -0.55% | – |
| GRCL | Exit | Gracell Biotechnologies Incsponsored ads | $0 | – | -961,359 | – | -0.60% | – |
| Exit | Dice Therapeutics Inc | $0 | – | -410,000 | – | -0.60% | – | |
| NKTX | Exit | Nkarta Inc | $0 | – | -512,225 | – | -0.64% | – |
| VRNA | Exit | Verona Pharma PLCads | $0 | – | -2,749,918 | – | -0.68% | – |
| MREO | Exit | Mereo Biopharma Group PLCads | $0 | – | -6,907,189 | – | -0.75% | – |
| ACRS | Exit | Aclaris Therapeutics, Inc. | $0 | – | -940,754 | – | -0.76% | – |
| ZLAB | Exit | Zai Lab Ltd ADRadr | $0 | – | -174,999 | – | -0.83% | – |
| Exit | Sera Prognostics Inc | $0 | – | -1,856,011 | – | -0.93% | – | |
| VRDN | Exit | Viridian Therapeutics Inc | $0 | – | -1,300,000 | – | -0.96% | – |
| LEGN | Exit | Legend Biotech Corp Sponsoredsponsored ads | $0 | – | -488,751 | – | -1.11% | – |
| CLDX | Exit | Celldex Therapeutics Inc | $0 | – | -484,453 | – | -1.17% | – |
| TERN | Exit | Terns Pharmaceuticals Inc | $0 | – | -2,675,133 | – | -1.25% | – |
| KALV | Exit | KalVista Pharmaceuticals Inc. | $0 | – | -1,641,913 | – | -1.29% | – |
| AVDL | Exit | Avadel Pharmaceuticals PLCadr | $0 | – | -2,937,093 | – | -1.29% | – |
| OLMA | Exit | Olema Pharmaceuticals Inc | $0 | – | -1,238,575 | – | -1.53% | – |
| IMPL | Exit | Impel NeuroPharma Inc | $0 | – | -2,884,789 | – | -1.58% | – |
| KDMN | Exit | Kadmon Holdings Inc | $0 | – | -4,283,014 | – | -1.68% | – |
| SVA | Exit | Sinovac Biotech Ltd. | $0 | – | -5,900,000 | – | -1.71% | – |
| Exit | Aadi Bioscience Inc | $0 | – | -1,427,213 | – | -1.88% | – | |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -1,917,074 | – | -1.89% | – |
| BOLT | Exit | Bolt Therapeutics Inc | $0 | – | -3,871,291 | – | -2.20% | – |
| ALGS | Exit | Aligos Therapeutics Inc | $0 | – | -3,547,030 | – | -2.47% | – |
| TARS | Exit | Tarsus Pharmaceuticals Inc | $0 | – | -2,987,331 | – | -2.89% | – |
| GTH | Exit | Genetron Holdings Ltdads | $0 | – | -6,339,860 | – | -3.94% | – |
| ISEE | Exit | Iveric Bio Inc | $0 | – | -5,966,527 | – | -4.35% | – |
| ASND | Exit | Ascendis Pharma A/Ssponsored adr | $0 | – | -760,606 | – | -5.44% | – |
| AMRS | Exit | Amyris, Inc | $0 | – | -11,642,195 | – | -7.18% | – |
| NFH | Exit | New Frontier Health Corp | $0 | – | -14,300,000 | – | -7.21% | – |
| HRMY | Exit | Harmony Biosciences Holdings Inc | $0 | – | -4,884,341 | – | -8.41% | – |
| TIL | Exit | Instil Bio Inc | $0 | – | -12,486,787 | – | -10.02% | – |
| ALXO | Exit | ALX Oncology Holdings Inc | $0 | – | -4,220,048 | – | -14.00% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HRMY | Buy | Harmony Biosciences Holdings Inc | $187,217,000 | +46.3% | 4,884,341 | +7.7% | 8.41% | +51.7% |
| AMRS | Buy | Amyris, Inc | $159,847,000 | -16.1% | 11,642,195 | +0.0% | 7.18% | -13.0% |
| ASND | Sell | Ascendis Pharma A/Ssponsored adr | $121,233,000 | -39.6% | 760,606 | -50.2% | 5.44% | -37.4% |
| New | Aadi Bioscience Inc | $41,917,000 | – | 1,427,213 | – | 1.88% | – | |
| KDMN | Sell | Kadmon Holdings Inc | $37,305,000 | +65.7% | 4,283,014 | -26.4% | 1.68% | +71.8% |
| KALV | Sell | KalVista Pharmaceuticals Inc. | $28,651,000 | -35.8% | 1,641,913 | -11.9% | 1.29% | -33.5% |
| CLDX | Sell | Celldex Therapeutics Inc | $26,156,000 | -19.3% | 484,453 | -50.0% | 1.17% | -16.3% |
| LEGN | Sell | Legend Biotech Corp Sponsoredsponsored ads | $24,711,000 | -37.1% | 488,751 | -48.9% | 1.11% | -34.7% |
| VRDN | New | Viridian Therapeutics Inc | $21,385,000 | – | 1,300,000 | – | 0.96% | – |
| New | Sera Prognostics Inc | $20,620,000 | – | 1,856,011 | – | 0.93% | – | |
| ZLAB | Sell | Zai Lab Ltd ADRadr | $18,443,000 | -40.5% | 174,999 | -0.0% | 0.83% | -38.3% |
| ACRS | Sell | Aclaris Therapeutics, Inc. | $16,934,000 | -29.8% | 940,754 | -31.5% | 0.76% | -27.3% |
| MREO | Buy | Mereo Biopharma Group PLCads | $16,715,000 | +24.9% | 6,907,189 | +63.6% | 0.75% | +29.7% |
| VRNA | Sell | Verona Pharma PLCads | $15,070,000 | -24.4% | 2,749,918 | -9.8% | 0.68% | -21.6% |
| New | Dice Therapeutics Inc | $13,428,000 | – | 410,000 | – | 0.60% | – | |
| GRCL | Sell | Gracell Biotechnologies Incsponsored ads | $13,334,000 | -22.8% | 961,359 | -27.6% | 0.60% | -19.8% |
| COGT | New | Cogent Biosciences Inc | $11,950,000 | – | 1,420,941 | – | 0.54% | – |
| CRNX | Sell | Crinetics Pharmaceuticals Inc | $10,889,000 | -67.0% | 517,280 | -70.5% | 0.49% | -65.8% |
| EPIX | Sell | Essa Pharma Inc | $8,449,000 | -80.9% | 1,056,067 | -31.9% | 0.38% | -80.3% |
| VALN | Sell | Valneva SEsponsored ads | $6,280,000 | -40.4% | 200,000 | -50.0% | 0.28% | -38.2% |
| PASG | Sell | Passage Bio Inc | $5,371,000 | -37.2% | 539,263 | -16.5% | 0.24% | -34.9% |
| LRMR | Sell | Larimar Therapeutics Inc | $4,610,000 | -41.3% | 399,830 | -50.0% | 0.21% | -39.1% |
| EIGR | Sell | Eiger BioPharmaceuticals Inc | $3,137,000 | -79.4% | 469,588 | -73.8% | 0.14% | -78.7% |
| TCDA | Sell | Tricida, Inc. | $779,000 | +3.2% | 167,863 | -3.9% | 0.04% | +6.1% |
| CALT | Exit | Calliditas Therapeutics ADRsponsored ads | $0 | – | -62,306 | – | -0.08% | – |
| IMVT | Exit | Immunovant Inc | $0 | – | -532,847 | – | -0.24% | – |
| CYTK | Exit | Cytokinetics Inc | $0 | – | -700,000 | – | -0.60% | – |
| NVAX | Exit | Novavax Inc | $0 | – | -88,046 | – | -0.81% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TIL | New | Instil Bio Inc | $241,245,000 | – | 12,486,787 | – | 10.44% | – |
| ALXO | New | ALX Oncology Holdings Inc | $230,752,000 | – | 4,220,048 | – | 9.99% | – |
| ASND | New | Ascendis Pharma A/Ssponsored adr | $200,793,000 | – | 1,526,359 | – | 8.69% | – |
| AMRS | New | Amyris, Inc | $190,546,000 | – | 11,639,929 | – | 8.25% | – |
| NFH | New | New Frontier Health Corp | $159,731,000 | – | 14,300,000 | – | 6.92% | – |
| HRMY | New | Harmony Biosciences Holdings Inc | $128,004,000 | – | 4,534,341 | – | 5.54% | – |
| GTH | New | Genetron Holdings Ltdads | $127,685,000 | – | 6,339,860 | – | 5.53% | – |
| TARS | New | Tarsus Pharmaceuticals Inc | $86,573,000 | – | 2,987,331 | – | 3.75% | – |
| ALGS | New | Aligos Therapeutics Inc | $72,306,000 | – | 3,547,030 | – | 3.13% | – |
| BOLT | New | Bolt Therapeutics Inc | $59,850,000 | – | 3,871,291 | – | 2.59% | – |
| KALV | New | KalVista Pharmaceuticals Inc. | $44,645,000 | – | 1,863,296 | – | 1.93% | – |
| EPIX | New | Essa Pharma Inc | $44,331,000 | – | 1,551,680 | – | 1.92% | – |
| LEGN | New | Legend Biotech Corp Sponsoredsponsored ads | $39,273,000 | – | 956,702 | – | 1.70% | – |
| SVA | New | Sinovac Biotech Ltd. | $38,173,000 | – | 5,900,000 | – | 1.65% | – |
| ISEE | New | Iveric Bio Inc | $37,649,000 | – | 5,966,527 | – | 1.63% | – |
| SRRA | New | Sierra Oncology, Inc | $37,325,000 | – | 1,917,074 | – | 1.62% | – |
| OLMA | New | Olema Pharmaceuticals Inc | $34,655,000 | – | 1,238,575 | – | 1.50% | – |
| CRNX | New | Crinetics Pharmaceuticals Inc | $33,032,000 | – | 1,752,346 | – | 1.43% | – |
| TERN | New | Terns Pharmaceuticals Inc | $32,797,000 | – | 2,675,133 | – | 1.42% | – |
| CLDX | New | Celldex Therapeutics Inc | $32,400,000 | – | 968,906 | – | 1.40% | – |
| ZLAB | New | Zai Lab Ltd ADRadr | $30,973,000 | – | 175,000 | – | 1.34% | – |
| IMPL | New | Impel NeuroPharma Inc | $25,530,000 | – | 2,884,789 | – | 1.10% | – |
| ACRS | New | Aclaris Therapeutics, Inc. | $24,132,000 | – | 1,374,279 | – | 1.04% | – |
| KDMN | New | Kadmon Holdings Inc | $22,514,000 | – | 5,817,459 | – | 0.98% | – |
| VRNA | New | Verona Pharma PLC ADRads | $19,937,000 | – | 3,048,507 | – | 0.86% | – |
| AVDL | New | Avadel Pharmaceuticals PLCadr | $19,767,000 | – | 2,937,093 | – | 0.86% | – |
| NVAX | New | Novavax Inc | $18,693,000 | – | 88,046 | – | 0.81% | – |
| GRCL | New | Gracell Biotechnologies Incsponsored ads | $17,267,000 | – | 1,328,257 | – | 0.75% | – |
| NKTX | New | Nkarta Inc | $16,232,000 | – | 512,225 | – | 0.70% | – |
| EIGR | New | Eiger BioPharmaceuticals Inc | $15,262,000 | – | 1,791,257 | – | 0.66% | – |
| CYTK | New | Cytokinetics Inc | $13,853,000 | – | 700,000 | – | 0.60% | – |
| MREO | New | Mereo Biopharma Group PLCads | $13,380,000 | – | 4,220,938 | – | 0.58% | – |
| CRIS | New | Curis Inc | $12,537,000 | – | 1,553,500 | – | 0.54% | – |
| KDNY | New | Chinook Therapeutics Inc | $12,315,000 | – | 872,151 | – | 0.53% | – |
| DYN | New | Dyne Therapeutics Inc | $12,154,000 | – | 577,642 | – | 0.53% | – |
| ARQT | New | Arcutis Biotherapeutics Inc | $11,833,000 | – | 433,585 | – | 0.51% | – |
| ARWR | New | Arrowhead Pharmaceuticals Inc | $11,380,000 | – | 137,411 | – | 0.49% | – |
| KURA | New | Kura Oncology Inc | $10,952,000 | – | 525,262 | – | 0.47% | – |
| DSGN | New | Design Therapeutics | $10,561,000 | – | 530,991 | – | 0.46% | – |
| VALN | New | Valneva SEsponsored ads | $10,540,000 | – | 400,000 | – | 0.46% | – |
| ZYME | New | Zymeworks Inc | $9,924,000 | – | 286,064 | – | 0.43% | – |
| ASLN | New | Aslan Pharmaceuticals Ltdads | $9,375,000 | – | 2,840,909 | – | 0.41% | – |
| MRUS | New | Merus NV | $9,313,000 | – | 442,000 | – | 0.40% | – |
| CDXS | New | Codexis, Inc | $8,795,000 | – | 388,144 | – | 0.38% | – |
| STSA | New | Satsuma Pharmaceuticals Inc | $8,688,000 | – | 1,232,394 | – | 0.38% | – |
| PASG | New | Passage Bio Inc | $8,553,000 | – | 646,001 | – | 0.37% | – |
| LRMR | New | Larimar Therapeutics Inc | $7,853,000 | – | 799,662 | – | 0.34% | – |
| ELEV | New | Elevation Oncology Inc | $6,742,000 | – | 496,843 | – | 0.29% | – |
| AUPH | New | Aurinia Pharmaceuticals Inc. | $6,489,000 | – | 500,732 | – | 0.28% | – |
| FIXX | New | Homology Medicines, Inc. | $6,202,000 | – | 853,143 | – | 0.27% | – |
| ORTX | New | Orchard Therapeutics plcads | $5,820,000 | – | 1,325,736 | – | 0.25% | – |
| IMVT | New | Immunovant Inc | $5,632,000 | – | 532,847 | – | 0.24% | – |
| SNDX | New | Syndax Pharmaceuticals Inc | $5,494,000 | – | 320,000 | – | 0.24% | – |
| TXG | New | 10X Genomics Inc | $2,898,000 | – | 14,798 | – | 0.12% | – |
| ZGNX | New | Zogenix Inc | $1,814,000 | – | 105,000 | – | 0.08% | – |
| CALT | New | Calliditas Therapeutics ADRsponsored ads | $1,835,000 | – | 62,306 | – | 0.08% | – |
| DTIL | New | Precision Biosciences Inc | $1,756,000 | – | 140,255 | – | 0.08% | – |
| TCDA | New | Tricida, Inc. | $755,000 | – | 174,763 | – | 0.03% | – |
| MTCR | New | Metacrine Inc | $556,000 | – | 146,426 | – | 0.02% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| DTIL | Exit | PRECISION BIOSCIENCES INC | $0 | – | -140,255 | – | -0.05% | – |
| MTCR | Exit | METACRINE INC | $0 | – | -146,426 | – | -0.09% | – |
| TCDA | Exit | TRICIDA INC | $0 | – | -174,763 | – | -0.09% | – |
| SELB | Exit | SELECTA BIOSCIENCES INC | $0 | – | -947,175 | – | -0.14% | – |
| MEIP | Exit | MEI PHARMA INC | $0 | – | -816,956 | – | -0.15% | – |
| ATRC | Exit | ATRICURE INC | $0 | – | -64,573 | – | -0.15% | – |
| AVRO | Exit | AVROBIO INC | $0 | – | -206,225 | – | -0.16% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -140,298 | – | -0.16% | – |
| VYNE | Exit | VYNE THERAPEUTICS INC | $0 | – | -1,821,912 | – | -0.18% | – |
| RVMD | Exit | REVOLUTION MEDICINES INC | $0 | – | -99,517 | – | -0.20% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -1,647,214 | – | -0.24% | – |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -145,417 | – | -0.25% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -183,042 | – | -0.27% | – |
| ORTX | Exit | ORCHARD THERAPEUTICS PLCads | $0 | – | -1,325,736 | – | -0.32% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -300,000 | – | -0.32% | – |
| KALA | Exit | KALA PHARMACEUTICALS INC | $0 | – | -786,883 | – | -0.34% | – |
| DYN | Exit | DYNE THERAPEUTICS INC | $0 | – | -315,000 | – | -0.37% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -1,250,000 | – | -0.42% | – |
| AUPH | Exit | AURINIA PHARMACEUTICALS INC | $0 | – | -500,732 | – | -0.43% | – |
| IGMS | Exit | IGM BIOSCIENCES INC | $0 | – | -103,480 | – | -0.44% | – |
| CVAC | Exit | CUREVAC N V | $0 | – | -169,825 | – | -0.46% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -926,449 | – | -0.48% | – |
| MTNB | Exit | MATINAS BIOPHARMA HLDGS INC | $0 | – | -11,279,323 | – | -0.50% | – |
| FIXX | Exit | HOMOLOGY MEDICINES INC | $0 | – | -853,143 | – | -0.53% | – |
| ZLAB | Exit | ZAI LAB LTDadr | $0 | – | -122,107 | – | -0.59% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -1,516,865 | – | -0.60% | – |
| LRMR | Exit | LARIMAR THERAPEUTICS INC | $0 | – | -799,662 | – | -0.70% | – |
| ADRO | Exit | ADURO BIOTECH INC | $0 | – | -5,118,560 | – | -0.72% | – |
| CALT | Exit | CALLIDITAS THERAPEUTICS ABsponsored ads | $0 | – | -580,000 | – | -0.80% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -1,791,257 | – | -0.84% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -817,935 | – | -0.85% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -2,089,356 | – | -0.87% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -700,000 | – | -0.88% | – |
| NKTX | Exit | NKARTA INC | $0 | – | -512,225 | – | -0.89% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -6,220,938 | – | -0.94% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -1,476,289 | – | -1.00% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -571,833 | – | -1.02% | – |
| KNSA | Exit | KINIKSA PHARMACEUTICALS LTD | $0 | – | -1,151,622 | – | -1.02% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCsponsored adr | $0 | – | -3,526,093 | – | -1.03% | – |
| NVAX | Exit | NOVAVAX INC | $0 | – | -164,199 | – | -1.03% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -1,476,796 | – | -1.07% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -3,048,507 | – | -1.10% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -860,648 | – | -1.14% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -1,917,074 | – | -1.18% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -5,291,336 | – | -1.20% | – |
| MYOK | Exit | MYOKARDIA INC | $0 | – | -158,310 | – | -1.25% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -353,511 | – | -1.25% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -576,505 | – | -1.44% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -1,722,500 | – | -1.48% | – |
| PASG | Exit | PASSAGE BIO INC | $0 | – | -2,191,453 | – | -1.66% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -640,411 | – | -1.72% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -1,050,000 | – | -1.86% | – |
| ARQT | Exit | ARCUTIS BIOTHERAPEUTICS INC | $0 | – | -1,113,265 | – | -1.88% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -5,966,527 | – | -1.94% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -2,263,770 | – | -2.05% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -1,042,460 | – | -2.12% | – |
| SVA | Exit | SINOVAC BIOTECH LTD | $0 | – | -5,900,000 | – | -2.21% | – |
| AMRS | Exit | AMYRIS INC | $0 | – | -13,158,914 | – | -2.22% | – |
| GTH | Exit | GENETRON HLDGS LTDads | $0 | – | -6,339,860 | – | -4.38% | – |
| LEGN | Exit | LEGEND BIOTECH CORPsponsored ads | $0 | – | -3,330,269 | – | -5.94% | – |
| NFH | Exit | NEW FRONTIER HEALTH CORP | $0 | – | -14,300,000 | – | -6.30% | – |
| HRMY | Exit | HARMONY BIOSCIENCES HLDGS IN | $0 | – | -4,534,341 | – | -8.88% | – |
| ALXO | Exit | ALX ONCOLOGY HLDGS INC | $0 | – | -4,220,048 | – | -9.20% | – |
| ASND | Exit | ASCENDIS PHARMA A/Ssponsored adr | $0 | – | -1,797,745 | – | -16.03% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALXO | New | ALX ONCOLOGY HLDGS INC | $159,265,000 | – | 4,220,048 | – | 9.20% | – |
| HRMY | New | HARMONY BIOSCIENCES HLDGS IN | $153,714,000 | – | 4,534,341 | – | 8.88% | – |
| LEGN | Sell | LEGEND BIOTECH CORPsponsored ads | $102,805,000 | -32.1% | 3,330,269 | -6.3% | 5.94% | -45.2% |
| AMRS | Buy | AMYRIS INC | $38,424,000 | -11.6% | 13,158,914 | +29.2% | 2.22% | -28.7% |
| IMVT | Buy | IMMUNOVANT INC | $36,684,000 | +88.3% | 1,042,460 | +30.3% | 2.12% | +51.8% |
| CRNX | Sell | CRINETICS PHARMACEUTICALS IN | $35,473,000 | -12.6% | 2,263,770 | -2.3% | 2.05% | -29.6% |
| ARQT | Sell | ARCUTIS BIOTHERAPEUTICS INC | $32,619,000 | -16.3% | 1,113,265 | -13.7% | 1.88% | -32.6% |
| ZYME | Sell | ZYMEWORKS INC | $29,830,000 | +12.6% | 640,411 | -12.8% | 1.72% | -9.2% |
| PASG | Sell | PASSAGE BIO INC | $28,730,000 | -52.9% | 2,191,453 | -1.7% | 1.66% | -62.0% |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $25,545,000 | +22.8% | 1,722,500 | +7.7% | 1.48% | -1.0% |
| SAGE | Buy | SAGE THERAPEUTICS INC | $21,607,000 | +51.4% | 353,511 | +3.0% | 1.25% | +22.1% |
| KDMN | Sell | KADMON HLDGS INC | $20,742,000 | -24.2% | 5,291,336 | -1.1% | 1.20% | -38.9% |
| SRRA | New | SIERRA ONCOLOGY INC | $20,455,000 | – | 1,917,074 | – | 1.18% | – |
| VRNA | Buy | VERONA PHARMA PLCsponsored ads | $19,023,000 | +172.3% | 3,048,507 | +104.2% | 1.10% | +119.4% |
| NVAX | New | NOVAVAX INC | $17,791,000 | – | 164,199 | – | 1.03% | – |
| AKRO | Sell | AKERO THERAPEUTICS INC | $17,607,000 | +19.5% | 571,833 | -3.3% | 1.02% | -3.6% |
| CDXS | Sell | CODEXIS INC | $17,332,000 | +1.8% | 1,476,289 | -1.2% | 1.00% | -17.9% |
| MREO | Buy | MEREO BIOPHARMA GROUP PLCads | $16,299,000 | +584.5% | 6,220,938 | +699.6% | 0.94% | +450.9% |
| NKTX | New | NKARTA INC | $15,397,000 | – | 512,225 | – | 0.89% | – |
| CYTK | New | CYTOKINETICS INC | $15,155,000 | – | 700,000 | – | 0.88% | – |
| ZGNX | Buy | ZOGENIX INC | $14,666,000 | -17.5% | 817,935 | +24.2% | 0.85% | -33.5% |
| EPIX | New | ESSA PHARMA INC | $10,466,000 | – | 1,516,865 | – | 0.60% | – |
| FIXX | Sell | HOMOLOGY MEDICINES INC | $9,129,000 | -31.4% | 853,143 | -2.6% | 0.53% | -44.7% |
| PSTX | New | POSEIDA THERAPEUTICS INC | $8,218,000 | – | 926,449 | – | 0.48% | – |
| CVAC | New | CUREVAC N V | $7,905,000 | – | 169,825 | – | 0.46% | – |
| IGMS | Sell | IGM BIOSCIENCES INC | $7,638,000 | -12.4% | 103,480 | -13.4% | 0.44% | -29.4% |
| OVID | New | OVID THERAPEUTICS INC | $7,175,000 | – | 1,250,000 | – | 0.42% | – |
| DYN | New | DYNE THERAPEUTICS INC | $6,360,000 | – | 315,000 | – | 0.37% | – |
| ATHA | New | ATHIRA PHARMA INC | $5,538,000 | – | 300,000 | – | 0.32% | – |
| ETNB | New | 89BIO INC | $4,697,000 | – | 183,042 | – | 0.27% | – |
| BDTX | Sell | BLACK DIAMOND THERAPEUTICS I | $4,396,000 | -30.7% | 145,417 | -3.3% | 0.25% | -44.2% |
| RVMD | Sell | REVOLUTION MEDICINES INC | $3,463,000 | -45.0% | 99,517 | -50.1% | 0.20% | -55.8% |
| VYNE | New | VYNE THERAPEUTICS INC | $3,024,000 | – | 1,821,912 | – | 0.18% | – |
| AVRO | Sell | AVROBIO INC | $2,685,000 | -39.3% | 206,225 | -18.7% | 0.16% | -51.1% |
| MEIP | Sell | MEI PHARMA INC | $2,549,000 | -43.0% | 816,956 | -24.5% | 0.15% | -54.1% |
| SELB | Sell | SELECTA BIOSCIENCES INC | $2,349,000 | -63.3% | 947,175 | -58.0% | 0.14% | -70.4% |
| TCDA | Sell | TRICIDA INC | $1,583,000 | -67.0% | 174,763 | -0.0% | 0.09% | -73.5% |
| MTCR | New | METACRINE INC | $1,495,000 | – | 146,426 | – | 0.09% | – |
| DBVT | Exit | DBV Technologies S.A.adr | $0 | – | -269,995 | – | -0.08% | – |
| GLMD | Exit | Galmed Pharmaceuticals Ltd | $0 | – | -860,103 | – | -0.30% | – |
| MNLO | Exit | Menlo Therapeutics Inc. | $0 | – | -3,643,824 | – | -0.45% | – |
| VSTM | Exit | Verastem Inc | $0 | – | -4,639,535 | – | -0.57% | – |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -1,917,074 | – | -1.66% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | New | Ascendis Pharma A/Sadr | $265,886,000 | – | 1,797,745 | – | 19.06% | – |
| LEGN | New | Legend Biotech Corp Sponsoredsponsored ads | $151,301,000 | – | 3,555,007 | – | 10.85% | – |
| NFH | New | New Frontier Health Corp | $118,404,000 | – | 14,300,000 | – | 8.49% | – |
| GTH | New | Genetron Holdings Ltdads | $76,522,000 | – | 6,339,860 | – | 5.49% | – |
| PASG | New | Passage Bio Inc | $60,935,000 | – | 2,229,587 | – | 4.37% | – |
| AMRS | New | Amyris, Inc | $43,475,000 | – | 10,181,472 | – | 3.12% | – |
| CRNX | New | Crinetics Pharmaceuticals Inc | $40,587,000 | – | 2,316,628 | – | 2.91% | – |
| ARQT | New | Arcutis Biotherapeutics Inc | $38,990,000 | – | 1,289,360 | – | 2.80% | – |
| SVA | New | Sinovac Biotech Ltd. | $38,173,000 | – | 5,900,000 | – | 2.74% | – |
| ISEE | New | Iveric Bio Inc | $30,429,000 | – | 5,966,527 | – | 2.18% | – |
| KNSA | New | Kiniksa Pharmaceuticals | $29,343,000 | – | 1,151,622 | – | 2.10% | – |
| AVDL | New | Avadel Pharmaceuticals PLCadr | $28,491,000 | – | 3,526,093 | – | 2.04% | – |
| KDMN | New | Kadmon Holdings Inc | $27,381,000 | – | 5,347,768 | – | 1.96% | – |
| ZYME | New | Zymeworks Inc | $26,481,000 | – | 734,161 | – | 1.90% | – |
| ARWR | New | Arrowhead Pharmaceuticals Inc | $24,899,000 | – | 576,505 | – | 1.78% | – |
| SRRA | New | Sierra Oncology, Inc | $23,197,000 | – | 1,917,074 | – | 1.66% | – |
| CLDX | New | Celldex Therapeutics Inc | $20,800,000 | – | 1,600,000 | – | 1.49% | – |
| IMVT | New | Immunovant Inc | $19,480,000 | – | 800,000 | – | 1.40% | – |
| RCKT | New | Rocket Pharmaceuticals Inc | $18,013,000 | – | 860,648 | – | 1.29% | – |
| KALV | New | KalVista Pharmaceuticals Inc. | $17,869,000 | – | 1,476,796 | – | 1.28% | – |
| ZGNX | New | Zogenix Inc | $17,787,000 | – | 658,523 | – | 1.28% | – |
| EIGR | New | Eiger BioPharmaceuticals Inc | $17,196,000 | – | 1,791,257 | – | 1.23% | – |
| KURA | New | Kura Oncology Inc | $17,115,000 | – | 1,050,000 | – | 1.23% | – |
| CDXS | New | Codexis, Inc | $17,030,000 | – | 1,493,903 | – | 1.22% | – |
| MYOK | New | Myokardia Inc | $15,296,000 | – | 158,310 | – | 1.10% | – |
| AKRO | New | Akero Therapeutics Inc | $14,732,000 | – | 591,169 | – | 1.06% | – |
| SAGE | New | Sage Therapeutics Inc | $14,269,000 | – | 343,179 | – | 1.02% | – |
| CALT | New | Calliditas Therapeutics ABsponsored ads | $13,456,000 | – | 580,000 | – | 0.96% | – |
| FIXX | New | Homology Medicines, Inc. | $13,302,000 | – | 875,696 | – | 0.95% | – |
| ADRO | New | Aduro Biotech Inc | $11,824,000 | – | 5,118,560 | – | 0.85% | – |
| LRMR | New | Larimar Therapeutics Inc | $10,276,000 | – | 799,662 | – | 0.74% | – |
| ZLAB | New | Zai Lab Limitedadr | $10,029,000 | – | 122,107 | – | 0.72% | – |
| IGMS | New | IGM Biosciences Inc | $8,722,000 | – | 119,480 | – | 0.62% | – |
| MTNB | New | Matinas Biopharma Hldgs Inc | $8,719,000 | – | 11,279,323 | – | 0.62% | – |
| KALA | New | Kala Pharmaceuticals, Inc. | $8,270,000 | – | 786,883 | – | 0.59% | – |
| AUPH | New | Aurinia Pharmaceuticals Inc. | $8,137,000 | – | 500,732 | – | 0.58% | – |
| VSTM | New | Verastem Inc | $7,980,000 | – | 4,639,535 | – | 0.57% | – |
| ORTX | New | Orchard Therapeutics plcads | $7,954,000 | – | 1,325,736 | – | 0.57% | – |
| CBAY | New | Cymabay Therapeutics Inc | $7,292,000 | – | 2,089,356 | – | 0.52% | – |
| VRNA | New | Verona Pharma PLCads | $6,987,000 | – | 1,492,951 | – | 0.50% | – |
| SELB | New | Selecta Biosciences Inc | $6,406,000 | – | 2,255,781 | – | 0.46% | – |
| BDTX | New | Black Diamond Therapeutics Inc | $6,339,000 | – | 150,349 | – | 0.46% | – |
| RVMD | New | Revolution Medicines Inc | $6,299,000 | – | 199,518 | – | 0.45% | – |
| MNLO | New | Menlo Therapeutics Inc. | $6,304,000 | – | 3,643,824 | – | 0.45% | – |
| TCDA | New | Tricida, Inc. | $4,803,000 | – | 174,764 | – | 0.34% | – |
| MEIP | New | MEI Pharma Inc | $4,469,000 | – | 1,082,080 | – | 0.32% | – |
| AVRO | New | Avrobio Inc | $4,426,000 | – | 253,625 | – | 0.32% | – |
| CNST | New | Constellation Pharmaceutical | $4,216,000 | – | 140,298 | – | 0.30% | – |
| GLMD | New | Galmed Pharmaceuticals Ltd | $4,111,000 | – | 860,103 | – | 0.30% | – |
| ATRC | New | Atricure Inc | $2,903,000 | – | 64,573 | – | 0.21% | – |
| ACRS | New | Aclaris Therapeutics, Inc. | $2,668,000 | – | 1,647,214 | – | 0.19% | – |
| MREO | New | Mereo Biopharma Group PLCads | $2,381,000 | – | 778,000 | – | 0.17% | – |
| DBVT | New | DBV Technologies S.A.adr | $1,185,000 | – | 269,995 | – | 0.08% | – |
| DTIL | New | Precision Biosciences Inc | $1,168,000 | – | 140,255 | – | 0.08% | – |
Q4 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Exit | Soleno Therapeutics, Inc. - Warrant834203135 | $0 | – | -188,772 | – | -0.00% | – | |
| Exit | Verona Pharma PLC925050106 | $0 | – | -2,805,035 | – | -2.55% | – | |
| Exit | Sinovac Biotech Ltd.p8696w104 | $0 | – | -9,610,156 | – | -5.49% | – | |
| Exit | Zai Lab Limited98887q104 | $0 | – | -2,552,237 | – | -23.66% | – | |
| Exit | Zymeworks Inch5861p103 | $0 | – | -82,834,668 | – | -68.30% | – |
Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | Zymeworks Inch5861p103 | $600,219,000 | – | 82,834,668 | – | 68.30% | – | |
| New | Zai Lab Limited98887q104 | $207,939,000 | – | 2,552,237 | – | 23.66% | – | |
| New | Sinovac Biotech Ltd.p8696w104 | $48,250,000 | – | 9,610,156 | – | 5.49% | – | |
| New | Verona Pharma PLC925050106 | $22,411,000 | – | 2,805,035 | – | 2.55% | – | |
| New | Soleno Therapeutics, Inc. - Warrant834203135 | $9,000 | – | 188,772 | – | 0.00% | – | |
| SLNOW | Exit | Soleno Therapeutics, Inc. - Warrantwarrant | $0 | – | -188,772 | – | -0.00% | – |
| BPMX | Exit | BioPharmX Corporation | $0 | – | -317,270 | – | -0.02% | – |
| AKTX | Exit | Akari Therapeutics Plcadr | $0 | – | -345,850 | – | -0.07% | – |
| SELB | Exit | Selecta Biosciences Inc | $0 | – | -546,054 | – | -0.09% | – |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -2,438,270 | – | -0.13% | – |
| AGRX | Exit | Agile Therapeutics, Inc. | $0 | – | -1,513,975 | – | -0.21% | – |
| DBVT | Exit | DBV Technologies S.A.adr | $0 | – | -269,995 | – | -0.21% | – |
| GNCA | Exit | Genocea Biosciences Inc | $0 | – | -626,401 | – | -0.23% | – |
| ACRS | Exit | Aclaris Therapeutics, Inc. | $0 | – | -1,647,214 | – | -0.34% | – |
| DTIL | Exit | Precision Biosciences Inc | $0 | – | -280,511 | – | -0.35% | – |
| ZGNX | Exit | Zogenix Inc | $0 | – | -105,000 | – | -0.47% | – |
| MTNB | Exit | Matinas Biopharma Hldgs Inc | $0 | – | -6,818,181 | – | -0.55% | – |
| KRTX | Exit | Karuna Therapeutics Inc | $0 | – | -325,000 | – | -0.61% | – |
| KALA | Exit | Kala Pharmaceuticals, Inc. | $0 | – | -1,043,020 | – | -0.62% | – |
| DERM | Exit | Dermira Inc | $0 | – | -700,000 | – | -0.63% | – |
| GLMD | Exit | Galmed Pharmaceuticals Ltd | $0 | – | -971,337 | – | -0.67% | – |
| VRNA | Exit | Verona Pharma PLCads | $0 | – | -1,492,951 | – | -0.71% | – |
| APLS | Exit | Apellis Pharmaceuticals, Inc. | $0 | – | -383,538 | – | -0.91% | – |
| Exit | Nabriva Therapeutics AG | $0 | – | -4,039,139 | – | -0.92% | – | |
| OBSV | Exit | Obseva SA | $0 | – | -937,147 | – | -0.99% | – |
| KNSA | Exit | Kiniksa Pharmaceuticals | $0 | – | -843,478 | – | -1.07% | – |
| RCKT | Exit | Rocket Pharmaceuticals Inc | $0 | – | -786,712 | – | -1.11% | – |
| SLNO | Exit | Soleno Therapeutics, Inc. | $0 | – | -4,268,959 | – | -1.12% | – |
| AUPH | Exit | Aurinia Pharmaceuticals Inc. | $0 | – | -1,913,623 | – | -1.18% | – |
| XENE | Exit | Xenon Pharmaceuticals Inc | $0 | – | -1,405,476 | – | -1.30% | – |
| MEIP | Exit | MEI Pharma Inc | $0 | – | -5,681,397 | – | -1.33% | – |
| CBAY | Exit | Cymabay Therapeutics Inc | $0 | – | -2,154,934 | – | -1.45% | – |
| CHMA | Exit | Chiasma Inc | $0 | – | -2,377,213 | – | -1.66% | – |
| ORTX | Exit | Orchard Therapeutics plcads | $0 | – | -1,312,084 | – | -1.72% | – |
| EIGR | Exit | Eiger BioPharmaceuticals Inc | $0 | – | -1,791,257 | – | -1.78% | – |
| FIXX | Exit | Homology Medicines, Inc. | $0 | – | -1,159,742 | – | -2.13% | – |
| AMRS | Exit | Amyris, Inc | $0 | – | -6,490,557 | – | -2.16% | – |
| MRTX | Exit | Mirati Therapeutics Inc. | $0 | – | -233,045 | – | -2.25% | – |
| MNLO | Exit | Menlo Therapeutics Inc. | $0 | – | -4,011,236 | – | -2.25% | – |
| MDCO | Exit | The Medicines Company | $0 | – | -669,012 | – | -2.29% | – |
| KDMN | Exit | Kadmon Holdings Inc | $0 | – | -12,606,605 | – | -2.43% | – |
| KALV | Exit | KalVista Pharmaceuticals Inc. | $0 | – | -1,359,149 | – | -2.82% | – |
| ZYME | Exit | Zymeworks Inc | $0 | – | -1,453,467 | – | -3.00% | – |
| SVA | Exit | Sinovac Biotech Ltd. | $0 | – | -5,900,000 | – | -3.58% | – |
| IOVA | Exit | Iovance Biotherapeutics, Inc. | $0 | – | -1,600,000 | – | -3.68% | – |
| INSM | Exit | Insmed Inc | $0 | – | -1,748,174 | – | -4.19% | – |
| CDXS | Exit | Codexis, Inc | $0 | – | -2,614,458 | – | -4.52% | – |
| TCDA | Exit | Tricida, Inc. | $0 | – | -1,424,525 | – | -5.27% | – |
| ARWR | Exit | Arrowhead Pharmaceuticals Inc | $0 | – | -2,765,153 | – | -6.87% | – |
| CRNX | Exit | Crinetics Pharmaceuticals Inc | $0 | – | -3,375,169 | – | -7.91% | – |
| ASND | Exit | Ascendis Pharma A/Sadr | $0 | – | -2,060,135 | – | -22.23% | – |
Q2 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | New | Ascendis Pharma A/Sadr | $237,225,000 | – | 2,060,135 | – | 22.23% | – |
| CRNX | New | Crinetics Pharmaceuticals Inc | $84,379,000 | – | 3,375,169 | – | 7.91% | – |
| ARWR | New | Arrowhead Pharmaceuticals Inc | $73,277,000 | – | 2,765,153 | – | 6.87% | – |
| TCDA | New | Tricida, Inc. | $56,212,000 | – | 1,424,525 | – | 5.27% | – |
| CDXS | New | Codexis, Inc | $48,184,000 | – | 2,614,458 | – | 4.52% | – |
| INSM | New | Insmed Inc | $44,753,000 | – | 1,748,174 | – | 4.19% | – |
| IOVA | New | Iovance Biotherapeutics, Inc. | $39,232,000 | – | 1,600,000 | – | 3.68% | – |
| SVA | New | Sinovac Biotech Ltd. | $38,173,000 | – | 5,900,000 | – | 3.58% | – |
| ZYME | New | Zymeworks Inc | $31,976,000 | – | 1,453,467 | – | 3.00% | – |
| KALV | New | KalVista Pharmaceuticals Inc. | $30,105,000 | – | 1,359,149 | – | 2.82% | – |
| KDMN | New | Kadmon Holdings Inc | $25,970,000 | – | 12,606,605 | – | 2.43% | – |
| MDCO | New | The Medicines Company | $24,399,000 | – | 669,012 | – | 2.29% | – |
| MNLO | New | Menlo Therapeutics Inc. | $24,027,000 | – | 4,011,236 | – | 2.25% | – |
| MRTX | New | Mirati Therapeutics Inc. | $24,004,000 | – | 233,045 | – | 2.25% | – |
| AMRS | New | Amyris, Inc | $23,106,000 | – | 6,490,557 | – | 2.16% | – |
| FIXX | New | Homology Medicines, Inc. | $22,696,000 | – | 1,159,742 | – | 2.13% | – |
| EIGR | New | Eiger BioPharmaceuticals Inc | $18,987,000 | – | 1,791,257 | – | 1.78% | – |
| ORTX | New | Orchard Therapeutics plcads | $18,356,000 | – | 1,312,084 | – | 1.72% | – |
| CHMA | New | Chiasma Inc | $17,758,000 | – | 2,377,213 | – | 1.66% | – |
| CBAY | New | Cymabay Therapeutics Inc | $15,429,000 | – | 2,154,934 | – | 1.45% | – |
| MEIP | New | MEI Pharma Inc | $14,203,000 | – | 5,681,397 | – | 1.33% | – |
| XENE | New | Xenon Pharmaceuticals Inc | $13,858,000 | – | 1,405,476 | – | 1.30% | – |
| AUPH | New | Aurinia Pharmaceuticals Inc. | $12,592,000 | – | 1,913,623 | – | 1.18% | – |
| SLNO | New | Soleno Therapeutics, Inc. | $11,953,000 | – | 4,268,959 | – | 1.12% | – |
| RCKT | New | Rocket Pharmaceuticals Inc | $11,801,000 | – | 786,712 | – | 1.11% | – |
| KNSA | New | Kiniksa Pharmaceuticals | $11,421,000 | – | 843,478 | – | 1.07% | – |
| OBSV | New | Obseva SA | $10,599,000 | – | 937,147 | – | 0.99% | – |
| New | Nabriva Therapeutics AG | $9,815,000 | – | 4,039,139 | – | 0.92% | – | |
| APLS | New | Apellis Pharmaceuticals, Inc. | $9,719,000 | – | 383,538 | – | 0.91% | – |
| VRNA | New | Verona Pharma PLCads | $7,614,000 | – | 1,492,951 | – | 0.71% | – |
| GLMD | New | Galmed Pharmaceuticals Ltd | $7,139,000 | – | 971,337 | – | 0.67% | – |
| DERM | New | Dermira Inc | $6,692,000 | – | 700,000 | – | 0.63% | – |
| KALA | New | Kala Pharmaceuticals, Inc. | $6,654,000 | – | 1,043,020 | – | 0.62% | – |
| KRTX | New | Karuna Therapeutics Inc | $6,507,000 | – | 325,000 | – | 0.61% | – |
| MTNB | New | Matinas Biopharma Hldgs Inc | $5,840,000 | – | 6,818,181 | – | 0.55% | – |
| ZGNX | New | Zogenix Inc | $5,017,000 | – | 105,000 | – | 0.47% | – |
| DTIL | New | Precision Biosciences Inc | $3,717,000 | – | 280,511 | – | 0.35% | – |
| ACRS | New | Aclaris Therapeutics, Inc. | $3,607,000 | – | 1,647,214 | – | 0.34% | – |
| GNCA | New | Genocea Biosciences Inc | $2,455,000 | – | 626,401 | – | 0.23% | – |
| DBVT | New | DBV Technologies S.A.adr | $2,219,000 | – | 269,995 | – | 0.21% | – |
| AGRX | New | Agile Therapeutics, Inc. | $2,210,000 | – | 1,513,975 | – | 0.21% | – |
| SRRA | New | Sierra Oncology, Inc | $1,365,000 | – | 2,438,270 | – | 0.13% | – |
| SELB | New | Selecta Biosciences Inc | $977,000 | – | 546,054 | – | 0.09% | – |
| AKTX | New | Akari Therapeutics Plcadr | $699,000 | – | 345,850 | – | 0.07% | – |
| BPMX | New | BioPharmX Corporation | $189,000 | – | 317,270 | – | 0.02% | – |
| SLNOW | New | Soleno Therapeutics, Inc. - Warrantwarrant | $19,000 | – | 188,772 | – | 0.00% | – |
Q4 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SLNOW | Exit | Soleno Therapeutics, Inc.warrant | $0 | – | -188,772 | – | -0.00% | – |
| GTXI | Exit | GTX Inc | $0 | – | -105,043 | – | -0.02% | – |
| SNSS | Exit | Sunesis Pharmaceuticals, Inc. | $0 | – | -195,474 | – | -0.04% | – |
| AGRX | Exit | Agile Therapeutics, Inc. | $0 | – | -1,513,975 | – | -0.06% | – |
| AKTX | Exit | Akari Therapeutics Plcadr | $0 | – | -345,850 | – | -0.09% | – |
| FOMX | Exit | Foamix Pharmaceuticals Ltd. | $0 | – | -427,500 | – | -0.25% | – |
| BPMX | Exit | BioPharmX Corporation | $0 | – | -16,128,515 | – | -0.31% | – |
| TRVN | Exit | Trevena, Inc. | $0 | – | -1,728,000 | – | -0.37% | – |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -2,438,270 | – | -0.42% | – |
| SBBP | Exit | Strongbridge Biopharma plc | $0 | – | -918,132 | – | -0.45% | – |
| ZLAB | Exit | Zai Lab LTDadr | $0 | – | -231,010 | – | -0.45% | – |
| ARVN | Exit | Arvinas Holding Co LLC | $0 | – | -300,000 | – | -0.51% | – |
| ZGNX | Exit | Zogenix, Inc. | $0 | – | -105,000 | – | -0.52% | – |
| GNCA | Exit | Genocea Biosciences Inc(NMS) | $0 | – | -8,180,000 | – | -0.64% | – |
| KNSA | Exit | Kiniksa Pharmaceuticals-A | $0 | – | -264,878 | – | -0.68% | – |
| AUPH | Exit | Aurinia Pharmaceuticals Inc. | $0 | – | -1,213,290 | – | -0.81% | – |
| DCPH | Exit | Deciphera Pharmaceuticals In | $0 | – | -212,648 | – | -0.83% | – |
| SLNO | Exit | Soleno Therapeutics, Inc. | $0 | – | -4,359,683 | – | -0.95% | – |
| ZYME | Exit | Zymeworks Inc | $0 | – | -620,134 | – | -0.98% | – |
| CBAY | Exit | Cymabay Therapeutics inc | $0 | – | -906,000 | – | -1.01% | – |
| KALA | Exit | Kala Pharmaceuticals, Inc. | $0 | – | -1,043,020 | – | -1.04% | – |
| GLMD | Exit | Galmed Pharmaceuticals Ltd | $0 | – | -851,492 | – | -1.16% | – |
| SELB | Exit | Selecta Biosciences, Inc. | $0 | – | -761,253 | – | -1.19% | – |
| OBSV | Exit | Obseva SA | $0 | – | -937,147 | – | -1.70% | – |
| ACER | Exit | Acer Therapeutics Inc | $0 | – | -565,579 | – | -1.76% | – |
| Exit | Nabriva Therapeutics Plc | $0 | – | -6,619,190 | – | -1.80% | – | |
| XENE | Exit | Xenon Pharmaceuticals Inc | $0 | – | -1,405,476 | – | -1.87% | – |
| VRNA | Exit | Verona Pharma Plcads | $0 | – | -1,492,951 | – | -1.88% | – |
| EIGR | Exit | Eiger BioPharmaceuticals | $0 | – | -1,791,257 | – | -2.17% | – |
| ACRS | Exit | Aclaris Therapeutics | $0 | – | -1,647,214 | – | -2.41% | – |
| APLS | Exit | Apellis Pharmaceuticals, Inc. | $0 | – | -1,354,554 | – | -2.43% | – |
| MEIP | Exit | MEI Pharma Inc (NAS) | $0 | – | -5,778,106 | – | -2.51% | – |
| FIXX | Exit | Homology Medicines, Inc. | $0 | – | -1,159,742 | – | -2.67% | – |
| KALV | Exit | KalVista Pharmaceuticals, Inc. | $0 | – | -1,359,149 | – | -3.03% | – |
| TCDA | Exit | Tricida, Inc. | $0 | – | -991,711 | – | -3.05% | – |
| KDMN | Exit | Kadmon Holdings (KDMN) | $0 | – | -10,454,545 | – | -3.52% | – |
| MNLO | Exit | Menlo Therapeutics | $0 | – | -4,011,236 | – | -3.98% | – |
| AMRS | Exit | Amyris, Inc. | $0 | – | -5,575,118 | – | -4.46% | – |
| ARWR | Exit | Arrowhead Pharmaceuticals In | $0 | – | -2,328,475 | – | -4.50% | – |
| SVA | Exit | Sinovac Biotech Ltd | $0 | – | -5,900,000 | – | -4.53% | – |
| CDXS | Exit | Codexis, Inc. | $0 | – | -2,749,343 | – | -4.75% | – |
| BHVN | Exit | Biohaven Pharmaceutical Holding Company Ltd | $0 | – | -2,049,545 | – | -7.76% | – |
| CRNX | Exit | Crinetics Pharmaceuticals Inc | $0 | – | -3,792,169 | – | -10.95% | – |
| ASND | Exit | Ascendis Pharmaadr | $0 | – | -2,166,832 | – | -15.48% | – |
Q3 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CRNX | New | Crinetics Pharmaceuticals Inc | $108,646,000 | – | 3,792,169 | – | 10.95% | – |
| CDXS | Sell | Codexis, Inc. | $47,151,000 | +7.2% | 2,749,343 | -10.0% | 4.75% | -16.2% |
| SVA | New | Sinovac Biotech Ltd | $44,958,000 | – | 5,900,000 | – | 4.53% | – |
| ARWR | Buy | Arrowhead Pharmaceuticals In | $44,637,000 | +72.7% | 2,328,475 | +22.6% | 4.50% | +35.1% |
| AMRS | Buy | Amyris, Inc. | $44,266,000 | +145.1% | 5,575,118 | +97.2% | 4.46% | +91.7% |
| KALV | Buy | KalVista Pharmaceuticals, Inc. | $30,051,000 | +1132.1% | 1,359,149 | +352.6% | 3.03% | +864.6% |
| FIXX | Sell | Homology Medicines, Inc. | $26,512,000 | -7.8% | 1,159,742 | -17.7% | 2.67% | -27.9% |
| MEIP | Sell | MEI Pharma Inc (NAS) | $24,904,000 | -4.2% | 5,778,106 | -12.5% | 2.51% | -25.1% |
| APLS | Sell | Apellis Pharmaceuticals, Inc. | $24,084,000 | -24.8% | 1,354,554 | -7.0% | 2.43% | -41.2% |
| XENE | New | Xenon Pharmaceuticals Inc | $18,552,000 | – | 1,405,476 | – | 1.87% | – |
| Buy | Nabriva Therapeutics Plc | $17,872,000 | +26.1% | 6,619,190 | +62.5% | 1.80% | -1.4% | |
| ACER | New | Acer Therapeutics Inc | $17,442,000 | – | 565,579 | – | 1.76% | – |
| OBSV | Buy | Obseva SA | $16,897,000 | +20.6% | 937,147 | +1.3% | 1.70% | -5.7% |
| SELB | Sell | Selecta Biosciences, Inc. | $11,837,000 | +14.4% | 761,253 | -2.5% | 1.19% | -10.5% |
| GLMD | Buy | Galmed Pharmaceuticals Ltd | $11,563,000 | +22.6% | 851,492 | +7.4% | 1.16% | -4.1% |
| DCPH | Sell | Deciphera Pharmaceuticals In | $8,234,000 | -17.3% | 212,648 | -15.9% | 0.83% | -35.3% |
| KNSA | Buy | Kiniksa Pharmaceuticals-A | $6,754,000 | +109.2% | 264,878 | +42.4% | 0.68% | +63.7% |
| ARVN | New | Arvinas Holding Co LLC | $5,061,000 | – | 300,000 | – | 0.51% | – |
| SBBP | Sell | Strongbridge Biopharma plc | $4,453,000 | -61.3% | 918,132 | -52.1% | 0.45% | -69.7% |
| FOMX | Sell | Foamix Pharmaceuticals Ltd. | $2,450,000 | -42.8% | 427,500 | -50.0% | 0.25% | -55.3% |
| GTXI | New | GTX Inc | $165,000 | – | 105,043 | – | 0.02% | – |
| RGNX | Exit | Regenxbio Inc. | $0 | – | -82,403 | – | -0.76% | – |
| MDGL | Exit | Madrigal Pharmaceuticals Inc | $0 | – | -62,220 | – | -2.24% | – |
Q2 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | New | Ascendis Pharmaadr | $144,138,000 | – | 2,166,832 | – | 18.57% | – |
| BHVN | New | Biohaven Pharmaceutical Holding Company Ltd | $80,998,000 | – | 2,049,545 | – | 10.44% | – |
| KDMN | New | Kadmon Holdings (KDMN) | $68,919,000 | – | 10,454,545 | – | 8.88% | – |
| CDXS | New | Codexis, Inc. | $43,989,000 | – | 3,054,825 | – | 5.67% | – |
| ACRS | New | Aclaris Therapeutics | $32,895,000 | – | 1,647,214 | – | 4.24% | – |
| MNLO | New | Menlo Therapeutics | $32,571,000 | – | 4,011,236 | – | 4.20% | – |
| APLS | New | Apellis Pharmaceuticals, Inc. | $32,043,000 | – | 1,456,499 | – | 4.13% | – |
| TCDA | New | Tricida, Inc. | $29,652,000 | – | 991,711 | – | 3.82% | – |
| FIXX | New | Homology Medicines, Inc. | $28,759,000 | – | 1,409,742 | – | 3.71% | – |
| MEIP | New | MEI Pharma Inc (NAS) | $26,007,000 | – | 6,600,660 | – | 3.35% | – |
| ARWR | New | Arrowhead Pharmaceuticals In | $25,840,000 | – | 1,900,000 | – | 3.33% | – |
| EIGR | New | Eiger BioPharmaceuticals | $21,853,000 | – | 1,791,257 | – | 2.82% | – |
| AMRS | New | Amyris, Inc. | $18,063,000 | – | 2,826,711 | – | 2.33% | – |
| MDGL | New | Madrigal Pharmaceuticals Inc | $17,402,000 | – | 62,220 | – | 2.24% | – |
| KALA | New | Kala Pharmaceuticals, Inc. | $14,321,000 | – | 1,043,020 | – | 1.84% | – |
| New | Nabriva Therapeutics Plc | $14,178,000 | – | 4,074,190 | – | 1.83% | – | |
| OBSV | New | Obseva SA | $14,005,000 | – | 925,000 | – | 1.80% | – |
| CBAY | New | Cymabay Therapeutics inc | $12,158,000 | – | 906,000 | – | 1.57% | – |
| SBBP | New | Strongbridge Biopharma plc | $11,509,000 | – | 1,918,132 | – | 1.48% | – |
| SELB | New | Selecta Biosciences, Inc. | $10,343,000 | – | 780,601 | – | 1.33% | – |
| SLNO | New | Soleno Therapeutics, Inc. | $10,202,000 | – | 4,359,683 | – | 1.32% | – |
| DCPH | New | Deciphera Pharmaceuticals In | $9,953,000 | – | 252,942 | – | 1.28% | – |
| GLMD | New | Galmed Pharmaceuticals Ltd | $9,433,000 | – | 792,707 | – | 1.22% | – |
| ZYME | New | Zymeworks Inc | $9,166,000 | – | 620,134 | – | 1.18% | – |
| SRRA | New | Sierra Oncology, Inc | $7,217,000 | – | 2,438,270 | – | 0.93% | – |
| GNCA | New | Genocea Biosciences Inc(NMS) | $7,000,000 | – | 8,180,000 | – | 0.90% | – |
| AUPH | New | Aurinia Pharmaceuticals Inc. | $6,831,000 | – | 1,213,290 | – | 0.88% | – |
| RGNX | New | Regenxbio Inc. | $5,912,000 | – | 82,403 | – | 0.76% | – |
| ZLAB | New | Zai Lab LTDadr | $5,371,000 | – | 231,010 | – | 0.69% | – |
| ZGNX | New | Zogenix, Inc. | $4,641,000 | – | 105,000 | – | 0.60% | – |
| FOMX | New | Foamix Pharmaceuticals Ltd. | $4,284,000 | – | 855,000 | – | 0.55% | – |
| BPMX | New | BioPharmX Corporation | $3,561,000 | – | 16,128,515 | – | 0.46% | – |
| KNSA | New | Kiniksa Pharmaceuticals-A | $3,228,000 | – | 186,073 | – | 0.42% | – |
| VRNA | New | Verona Pharma Plcads | $2,792,000 | – | 1,492,951 | – | 0.36% | – |
| TRVN | New | Trevena, Inc. | $2,488,000 | – | 1,728,000 | – | 0.32% | – |
| KALV | New | KalVista Pharmaceuticals, Inc. | $2,439,000 | – | 300,325 | – | 0.31% | – |
| AGRX | New | Agile Therapeutics, Inc. | $742,000 | – | 1,513,975 | – | 0.10% | – |
| AKTX | New | Akari Therapeutics Plcadr | $674,000 | – | 345,850 | – | 0.09% | – |
| SNSS | New | Sunesis Pharmaceuticals, Inc. | $414,000 | – | 195,474 | – | 0.05% | – |
| SLNOW | New | Soleno Therapeutics, Inc.warrant | $79,000 | – | 188,772 | – | 0.01% | – |
Q4 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SLNOW | Exit | Soleno Therapeutics, Inc. (W)warrant | $0 | – | -943,858 | – | -0.02% | – |
| SNSS | Exit | Sunesis Pharmaceuticals, Inc. | $0 | – | -500,000 | – | -0.20% | – |
| KALV | Exit | KalVista Pharmaceuticals, Inc. | $0 | – | -300,325 | – | -0.41% | – |
| AKTX | Exit | Akari Therapeutics Plcadr | $0 | – | -345,850 | – | -0.43% | – |
| RVNC | Exit | ReVance Therapeutics, Inc. | $0 | – | -77,373 | – | -0.43% | – |
| CRSP | Exit | CRISPR Therapeutics AGnamen akt | $0 | – | -148,878 | – | -0.54% | – |
| SRRA | Exit | Sierra Oncology, Inc | $0 | – | -2,438,270 | – | -0.76% | – |
| BPMX | Exit | BioPharmX Corporation | $0 | – | -14,096,338 | – | -0.82% | – |
| TRVN | Exit | Trevena, Inc. | $0 | – | -1,728,000 | – | -0.89% | – |
| FOMX | Exit | Foamix Pharmaceuticals Ltd. | $0 | – | -855,000 | – | -0.96% | – |
| RGNX | Exit | Regenxbio Inc. | $0 | – | -164,403 | – | -1.10% | – |
| AGRX | Exit | Agile Therapeutics, Inc. | $0 | – | -1,513,975 | – | -1.36% | – |
| AUPH | Exit | Aurinia Pharmaceuticals Inc. | $0 | – | -1,213,290 | – | -1.54% | – |
| SLNO | Exit | Soleno Therapeutics, Inc. | $0 | – | -14,695,264 | – | -1.54% | – |
| ZLAB | Exit | Zai Labadr | $0 | – | -325,000 | – | -1.77% | – |
| AMRS | Exit | Amyris | $0 | – | -2,826,711 | – | -1.83% | – |
| KDMN | Exit | Kadmon Holdings, Inc. | $0 | – | -3,333,333 | – | -2.26% | – |
| AAAP | Exit | Advanced Accelerator Applications S.A.ads | $0 | – | -249,241 | – | -3.41% | – |
| AIMT | Exit | Aimmune Therapeutics, Inc. | $0 | – | -776,813 | – | -3.89% | – |
| EIGR | Exit | Eiger BioPharmaceuticals | $0 | – | -1,787,091 | – | -3.97% | – |
| CDXS | Exit | Codexis, Inc. | $0 | – | -3,054,825 | – | -4.11% | – |
| SELB | Exit | Selecta Biosciences, Inc. | $0 | – | -1,119,189 | – | -4.13% | – |
| SBBP | Exit | Strongbridge Biopharma plcordinary shares | $0 | – | -2,962,645 | – | -4.13% | – |
| VRNA | Exit | Verona Pharma Plcads | $0 | – | -1,492,951 | – | -4.63% | – |
| KALA | Exit | Kala Pharmaceuticals Inc. | $0 | – | -1,158,911 | – | -5.35% | – |
| Exit | Nabriva Therapeutics PLC | $0 | – | -4,074,190 | – | -6.74% | – | |
| ASND | Exit | Ascendis Pharmaadr | $0 | – | -1,766,832 | – | -12.94% | – |
| ACRS | Exit | Aclaris Therapeutics | $0 | – | -2,858,569 | – | -14.91% | – |
| BHVN | Exit | Biohaven Pharmaceutical Holding Company Ltd | $0 | – | -1,976,818 | – | -14.93% | – |
Q3 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BHVN | New | Biohaven Pharmaceutical Holding Company Ltd | $73,893,000 | – | 1,976,818 | – | 14.93% | – |
| New | Nabriva Therapeutics PLC | $33,368,000 | – | 4,074,190 | – | 6.74% | – | |
| KALA | New | Kala Pharmaceuticals Inc. | $26,470,000 | – | 1,158,911 | – | 5.35% | – |
| VRNA | Buy | Verona Pharma Plcads | $22,917,000 | +179.2% | 1,492,951 | +112.0% | 4.63% | +124.0% |
| SBBP | Sell | Strongbridge Biopharma plcordinary shares | $20,442,000 | -4.7% | 2,962,645 | -1.2% | 4.13% | -23.5% |
| CDXS | Sell | Codexis, Inc. | $20,315,000 | -29.6% | 3,054,825 | -42.3% | 4.11% | -43.5% |
| AAAP | Sell | Advanced Accelerator Applications S.A.ads | $16,854,000 | +20.3% | 249,241 | -30.5% | 3.41% | -3.5% |
| KDMN | New | Kadmon Holdings, Inc. | $11,167,000 | – | 3,333,333 | – | 2.26% | – |
| AMRS | New | Amyris | $9,045,000 | – | 2,826,711 | – | 1.83% | – |
| ZLAB | New | Zai Labadr | $8,775,000 | – | 325,000 | – | 1.77% | – |
| SLNO | New | Soleno Therapeutics, Inc. | $7,642,000 | – | 14,695,264 | – | 1.54% | – |
| AUPH | Buy | Aurinia Pharmaceuticals Inc. | $7,607,000 | +22.5% | 1,213,290 | +19.8% | 1.54% | -1.7% |
| SRRA | New | Sierra Oncology, Inc | $3,779,000 | – | 2,438,270 | – | 0.76% | – |
| AKTX | Sell | Akari Therapeutics Plcadr | $2,124,000 | -12.7% | 345,850 | -34.5% | 0.43% | -30.0% |
| KALV | New | KalVista Pharmaceuticals, Inc. | $2,021,000 | – | 300,325 | – | 0.41% | – |
| SLNOW | New | Soleno Therapeutics, Inc. (W)warrant | $112,000 | – | 943,858 | – | 0.02% | – |
| CAPNW | Exit | Capnia, Inc.warrant | $0 | – | -943,858 | – | -0.04% | – |
| Exit | KalVista Pharmaceuticals, Inc. | $0 | – | -300,325 | – | -0.56% | – | |
| DNAI | Exit | Sierra Oncology, Inc. | $0 | – | -2,438,270 | – | -0.72% | – |
| DVAX | Exit | Dynavax Technologies Corporation | $0 | – | -359,827 | – | -0.87% | – |
| CAPN | Exit | Capnia, Inc. | $0 | – | -14,695,264 | – | -1.85% | – |
| NBRV | Exit | Nabriva Therapeutics AGadr | $0 | – | -4,021,559 | – | -10.61% | – |
| Exit | Biohaven Pharmaceutical Holding Company Ltd | $0 | – | -1,976,818 | – | -12.45% | – |
Q2 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ACRS | New | Aclaris therapeutics | $77,524,000 | – | 2,858,569 | – | 19.52% | – |
| New | Biohaven Pharmaceutical Holding Company Ltd | $49,420,000 | – | 1,976,818 | – | 12.45% | – | |
| ASND | New | Ascendis Pharmaadr | $49,047,000 | – | 1,766,832 | – | 12.35% | – |
| NBRV | New | Nabriva Therapeutics AGadr | $42,146,000 | – | 4,021,559 | – | 10.61% | – |
| CDXS | New | Codexis, Inc. | $28,857,000 | – | 5,294,825 | – | 7.27% | – |
| SELB | New | Selecta Biosciences, Inc. | $22,227,000 | – | 1,119,189 | – | 5.60% | – |
| SBBP | New | Strongbridge Biopharma plcordinary shares | $21,450,000 | – | 3,000,000 | – | 5.40% | – |
| AIMT | New | Aimmune Therapeutics, Inc. | $15,971,000 | – | 776,813 | – | 4.02% | – |
| EIGR | New | Eiger BioPharmaceuticals | $14,118,000 | – | 1,787,091 | – | 3.56% | – |
| AAAP | New | Advanced Accelerator Applications S.A. | $14,007,000 | – | 358,786 | – | 3.53% | – |
| VRNA | New | Verona Pharma Plcads | $8,208,000 | – | 704,225 | – | 2.07% | – |
| CAPN | New | Capnia, Inc. | $7,362,000 | – | 14,695,264 | – | 1.85% | – |
| BPMX | New | BioPharmX Corporation | $6,752,000 | – | 14,096,338 | – | 1.70% | – |
| AUPH | New | Aurinia Pharmaceuticals Inc. | $6,211,000 | – | 1,013,149 | – | 1.56% | – |
| AGRX | New | Agile Therapeutics, Inc. | $5,677,000 | – | 1,513,975 | – | 1.43% | – |
| TRVN | New | Trevena, Inc. | $3,974,000 | – | 1,728,000 | – | 1.00% | – |
| FOMX | New | Foamix Pharmaceuticals Ltd. | $3,967,000 | – | 855,000 | – | 1.00% | – |
| DVAX | New | Dynavax Technologies Corporation | $3,472,000 | – | 359,827 | – | 0.87% | – |
| RGNX | New | Regenxbio Inc. | $3,247,000 | – | 164,403 | – | 0.82% | – |
| DNAI | New | Sierra Oncology, Inc. | $2,853,000 | – | 2,438,270 | – | 0.72% | – |
| AKTX | New | Akari Therapeutics Plcadr | $2,433,000 | – | 527,842 | – | 0.61% | – |
| CRSP | New | CRISPR Therapeutics AG | $2,385,000 | – | 148,878 | – | 0.60% | – |
| New | KalVista Pharmaceuticals, Inc. | $2,210,000 | – | 300,325 | – | 0.56% | – | |
| RVNC | New | ReVance Therapeutics, Inc. | $2,043,000 | – | 77,373 | – | 0.52% | – |
| SNSS | New | Sunesis Pharmaceuticals, Inc. | $1,350,000 | – | 500,000 | – | 0.34% | – |
| CAPNW | New | Capnia, Inc.warrant | $159,000 | – | 943,858 | – | 0.04% | – |
Q4 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ZSAN | Exit | Zosano Pharma Corp | $0 | – | -98,515 | – | -0.02% | – |
| PTN | Exit | Palatin Technologies, Inc. | $0 | – | -234,909 | – | -0.05% | – |
| CAPNW | Exit | Capnia, Inc.warrant | $0 | – | -943,858 | – | -0.06% | – |
| OCRX | Exit | Ocera Therapeutics, Inc. | $0 | – | -153,331 | – | -0.13% | – |
| RVNC | Exit | ReVance Therapeutics, Inc. | $0 | – | -77,373 | – | -0.39% | – |
| CBYL | Exit | Carbylan Therapeutics | $0 | – | -4,204,562 | – | -0.60% | – |
| DVAX | Exit | Dynavax Technologies Corporation | $0 | – | -359,828 | – | -1.18% | – |
| DNAI | Exit | ProNAi Therapeutics, Inc. | $0 | – | -2,438,270 | – | -1.38% | – |
| AKTX | Exit | Akari Therapeutics Plcadr | $0 | – | -527,842 | – | -1.40% | – |
| CAPN | Exit | Capnia, Inc. | $0 | – | -7,456,984 | – | -2.09% | – |
| FOMX | Exit | Foamix Pharmaceuticals Ltd. | $0 | – | -855,000 | – | -2.47% | – |
| CLCD | Exit | CoLucid Pharmaceuticals, Inc. | $0 | – | -225,000 | – | -2.68% | – |
| AIMT | Exit | Aimmune Therapeutics, Inc. | $0 | – | -763,009 | – | -3.57% | – |
| TRVN | Exit | Trevena, Inc. | $0 | – | -1,728,000 | – | -3.64% | – |
| RGNX | Exit | Regenxbio Inc. | $0 | – | -990,449 | – | -4.32% | – |
| AGRX | Exit | Agile Therapeutics, Inc. | $0 | – | -2,019,955 | – | -4.39% | – |
| AAAP | Exit | Advanced Accelerator Applications S.A. | $0 | – | -455,798 | – | -5.41% | – |
| NBRV | Exit | Nabriva Therapeutics AGadr | $0 | – | -3,151,700 | – | -6.92% | – |
| CDXS | Exit | Codexis, Inc. | $0 | – | -5,294,825 | – | -7.33% | – |
| EIGR | Exit | Eiger BioPharmaceuticals | $0 | – | -1,787,091 | – | -7.46% | – |
| ASND | Exit | Ascendis Pharmaadr | $0 | – | -1,766,832 | – | -11.07% | – |
| ACRS | Exit | Aclaris therapeutics | $0 | – | -4,191,397 | – | -33.45% | – |
Q3 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| EIGR | Buy | Eiger BioPharmaceuticals | $23,929,000 | -24.5% | 1,787,091 | +11.7% | 7.46% | -13.9% |
| CDXS | Sell | Codexis, Inc. | $23,509,000 | +4.7% | 5,294,825 | -5.0% | 7.33% | +19.4% |
| CLCD | New | CoLucid Pharmaceuticals, Inc. | $8,584,000 | – | 225,000 | – | 2.68% | – |
| FOMX | New | Foamix Pharmaceuticals Ltd. | $7,917,000 | – | 855,000 | – | 2.47% | – |
| MEIP | Exit | MEI Pharma, Inc. | $0 | – | -1,101,129 | – | -0.41% | – |
| NERV | Exit | Minerva Neurosciences, Inc. | $0 | – | -200,000 | – | -0.56% | – |
| SGNT | Exit | Sagent Pharmaceuticals, Inc. | $0 | – | -6,495,416 | – | -26.57% | – |
Q2 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SGNT | New | Sagent Pharmaceuticals, Inc. | $97,301,000 | – | 6,495,416 | – | 26.57% | – |
| ACRS | New | Aclaris therapeutics | $77,415,000 | – | 4,191,397 | – | 21.14% | – |
| EIGR | New | Eiger BioPharmaceuticals | $31,704,000 | – | 1,599,591 | – | 8.66% | – |
| NBRV | New | Nabriva Therapeutics AGadr | $23,638,000 | – | 3,151,700 | – | 6.46% | – |
| ASND | New | Ascendis Pharmaadr | $23,446,000 | – | 1,766,832 | – | 6.40% | – |
| CDXS | New | Codexis, Inc. | $22,460,000 | – | 5,573,319 | – | 6.13% | – |
| AGRX | New | Agile Therapeutics, Inc. | $15,372,000 | – | 2,019,955 | – | 4.20% | – |
| AAAP | New | Advanced Accelerator Applications S.A. | $13,781,000 | – | 455,798 | – | 3.76% | – |
| TRVN | New | Trevena, Inc. | $10,886,000 | – | 1,728,000 | – | 2.97% | – |
| CAPN | New | Capnia, Inc. | $8,650,000 | – | 7,456,984 | – | 2.36% | – |
| AIMT | New | Aimmune Therapeutics, Inc. | $8,256,000 | – | 763,009 | – | 2.26% | – |
| RGNX | New | Regenxbio Inc. | $7,924,000 | – | 990,449 | – | 2.16% | – |
| AKTX | New | Akari Therapeutics Plcadr | $7,121,000 | – | 527,842 | – | 1.94% | – |
| DVAX | New | Dynavax Technologies Corporation | $5,246,000 | – | 359,828 | – | 1.43% | – |
| DNAI | New | ProNAi Therapeutics, Inc. | $4,852,000 | – | 2,438,270 | – | 1.32% | – |
| CBYL | New | Carbylan Therapeutics | $2,775,000 | – | 4,204,562 | – | 0.76% | – |
| NERV | New | Minerva Neurosciences, Inc. | $2,042,000 | – | 200,000 | – | 0.56% | – |
| MEIP | New | MEI Pharma, Inc. | $1,498,000 | – | 1,101,129 | – | 0.41% | – |
| RVNC | New | ReVance Therapeutics, Inc. | $1,052,000 | – | 77,373 | – | 0.29% | – |
| OCRX | New | Ocera Therapeutics, Inc. | $291,000 | – | 153,331 | – | 0.08% | – |
| CAPNW | New | Capnia, Inc.warrant | $245,000 | – | 943,858 | – | 0.07% | – |
| ZSAN | New | Zosano Pharma Corp | $125,000 | – | 98,515 | – | 0.03% | – |
| PTN | New | Palatin Technologies, Inc. | $103,000 | – | 234,909 | – | 0.03% | – |