Bellevue Group AG Activity Q1 2016-Q3 2023

Q3 2023

			Value		Shares		↓ Weighting
ARGX	Sell	ARGENX SEsponsored adr	$448,135,494	+24.5%	911,530	-1.3%	7.22%	+40.7%
IONS	Sell	IONIS PHARMACEUTICALS INC	$418,840,632	+8.8%	9,233,700	-1.6%	6.75%	+22.9%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$348,691,069	-9.7%	1,002,735	-8.6%	5.62%	+2.0%
NBIX	Sell	NEUROCRINE BIOSCIENCES INC	$290,649,375	+18.0%	2,583,550	-1.1%	4.68%	+33.2%
ISRG	Sell	INTUITIVE SURGICAL INC	$242,308,117	-15.9%	828,999	-1.6%	3.90%	-5.0%
ITCI	Sell	INTRA-CELLULAR THERAPIES INC	$165,138,323	-18.5%	3,170,250	-1.0%	2.66%	-8.0%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$158,388,500	-7.3%	894,345	-0.6%	2.55%	+4.7%
MRNA	Sell	MODERNA INC	$154,452,120	-16.6%	1,495,325	-1.9%	2.49%	-5.9%
ABT	Sell	ABBOTT LABS	$151,179,751	-15.8%	1,560,968	-5.2%	2.44%	-4.8%
INCY	Sell	INCYTE CORP	$143,931,067	-12.4%	2,491,450	-5.7%	2.32%	-1.1%
BSX	Sell	BOSTON SCIENTIFIC CORP	$139,724,376	-2.9%	2,646,295	-0.6%	2.25%	+9.6%
RVMD	Sell	REVOLUTION MEDICINES INC	$130,691,120	+2.9%	4,721,500	-0.5%	2.11%	+16.3%
UNH	Buy	UNITEDHEALTH GROUP INC	$130,184,379	+28.9%	258,205	+22.9%	2.10%	+45.5%
SYK	Sell	STRYKER CORPORATION	$129,970,765	-10.7%	475,613	-0.3%	2.09%	+0.9%
AXNX	Buy	AXONICS INC	$126,429,998	+12.7%	2,252,851	+1.3%	2.04%	+27.2%
EVH	Buy	EVOLENT HEALTH INCcl a	$100,127,842	-4.2%	3,677,115	+6.6%	1.61%	+8.3%
HUM	Buy	HUMANA INC	$82,730,780	+45.3%	170,046	+33.5%	1.33%	+64.2%
INSM	Sell	INSMED INC	$79,859,059	+14.7%	3,162,735	-4.2%	1.29%	+29.5%
BDX	Sell	BECTON DICKINSON & CO	$78,652,582	-11.8%	304,230	-9.9%	1.27%	-0.4%
EXAS	Buy	EXACT SCIENCES CORP	$76,394,052	-19.2%	1,119,819	+11.2%	1.23%	-8.7%
ANTM	Buy	ELEVANCE HEALTH INC	$75,713,877	+66.3%	173,887	+69.7%	1.22%	+88.0%
OPCH	Sell	OPTION CARE HEALTH INC	$73,896,879	-0.6%	2,284,293	-0.1%	1.19%	+12.4%
SAGE	Buy	SAGE THERAPEUTICS INC	$72,304,764	-50.6%	3,513,351	+12.8%	1.16%	-44.2%
EW	Sell	EDWARDS LIFESCIENCES CORP	$71,043,661	-27.4%	1,025,457	-1.2%	1.14%	-18.0%
DXCM	Sell	DEXCOM INC	$63,978,889	-34.6%	685,733	-10.0%	1.03%	-26.1%
PACB	Sell	PACIFIC BIOSCIENCES CALIF IN	$60,497,320	-39.7%	7,245,188	-3.9%	0.98%	-31.9%
PEN	Buy	PENUMBRA INC	$57,393,631	-28.8%	237,252	+1.3%	0.92%	-19.6%
CLDX	Buy	CELLDEX THERAPEUTICS INC NEW	$52,288,000	-14.4%	1,900,000	+5.6%	0.84%	-3.3%
MOH	Sell	MOLINA HEALTHCARE INC	$51,950,236	+4.9%	158,438	-3.6%	0.84%	+18.6%
EXEL	Sell	EXELIXIS INC	$51,913,961	+7.2%	2,375,925	-6.2%	0.84%	+21.0%
ALGN	Sell	ALIGN TECHNOLOGY INC	$50,953,634	-15.8%	166,886	-2.5%	0.82%	-4.9%
SWAV	Sell	SHOCKWAVE MED INC	$50,626,949	-34.4%	254,279	-6.0%	0.82%	-25.9%
MDT	Sell	MEDTRONIC PLC	$50,267,313	-59.5%	641,492	-54.5%	0.81%	-54.3%
BIO	Sell	BIO RAD LABS INCcl a	$48,150,589	-5.6%	134,330	-0.2%	0.78%	+6.6%
ACCD	Buy	ACCOLADE INC	$47,905,425	-21.3%	4,527,923	+0.2%	0.77%	-11.2%
MGNX	Buy	MACROGENICS INC	$45,683,439	-11.1%	9,803,313	+2.0%	0.74%	+0.4%
VEEV	Sell	VEEVA SYS INC	$45,593,145	-14.9%	224,100	-17.3%	0.74%	-3.8%
CRL	Sell	CHARLES RIV LABS INTL INC	$44,946,445	-32.0%	229,342	-27.1%	0.72%	-23.2%
TNDM	Buy	TANDEM DIABETES CARE INC	$44,505,312	-13.3%	2,142,769	+2.4%	0.72%	-2.2%
AXSM	Buy	AXSOME THERAPEUTICS INC	$44,134,626	+6.9%	631,487	+9.9%	0.71%	+20.7%
LLY	Sell	ELI LILLY & CO	$43,798,117	-1.9%	81,541	-14.3%	0.71%	+10.8%
PODD	Sell	INSULET CORP	$42,162,617	-54.8%	264,359	-18.3%	0.68%	-49.0%
ARVN	Sell	ARVINAS INC	$41,738,928	-20.9%	2,125,200	-0.1%	0.67%	-10.8%
RLAY	Buy	RELAY THERAPEUTICS INC	$41,082,850	-21.6%	4,885,000	+17.1%	0.66%	-11.4%
CRSP	Sell	CRISPR THERAPEUTICS AGnamen akt	$40,778,376	-19.2%	898,400	-0.1%	0.66%	-8.8%
HCA	Sell	HCA HEALTHCARE INC	$38,285,065	-21.4%	155,643	-3.0%	0.62%	-11.2%
CI	Buy	THE CIGNA GROUP	$35,902,357	+153.9%	125,502	+149.0%	0.58%	+186.1%
JAZZ	Sell	JAZZ PHARMACEUTICALS PLC	$34,460,293	-3.7%	266,226	-7.8%	0.56%	+8.6%
DHR	Sell	DANAHER CORPORATION	$33,873,837	-23.2%	136,533	-25.7%	0.55%	-13.2%
TMO	Sell	THERMO FISHER SCIENTIFIC INC	$33,644,108	-32.9%	66,468	-30.8%	0.54%	-24.2%
ATRC	Sell	ATRICURE INC	$32,743,128	-11.4%	747,560	-0.1%	0.53%	+0.2%
ZBH	Buy	ZIMMER BIOMET HOLDINGS INC	$31,970,131	-22.9%	284,888	+0.0%	0.52%	-13.0%
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$30,958,090	-1.0%	349,888	-3.0%	0.50%	+11.9%
HCM	Sell	HUTCHMED CHINA LTDsponsored ads	$30,584,761	+41.2%	1,802,963	-0.1%	0.49%	+59.5%
CNC	Buy	CENTENE CORP DEL	$30,585,682	+55.0%	444,043	+51.8%	0.49%	+75.4%
IQV	Sell	IQVIA HLDGS INC	$30,539,535	-16.2%	155,220	-4.3%	0.49%	-5.4%
GMED	Sell	GLOBUS MED INCcl a	$30,267,385	-21.5%	609,615	-5.9%	0.49%	-11.3%
APLS	Buy	APELLIS PHARMACEUTICALS INC	$30,197,712	-36.1%	793,841	+53.1%	0.49%	-27.7%
MRK	Sell	MERCK & CO INC	$30,050,693	-15.1%	291,896	-4.8%	0.48%	-4.2%
TMDX	Sell	TRANSMEDICS GROUP INC	$29,386,351	-42.9%	536,737	-12.4%	0.47%	-35.6%
SRPT	Buy	SAREPTA THERAPEUTICS INC	$29,305,177	+27.8%	241,752	+20.7%	0.47%	+44.3%
	Buy	PROCEPT BIOROBOTICS CORP	$29,144,992	+11.2%	888,296	+19.8%	0.47%	+25.7%
CDNA	Buy	CAREDX INC	$27,585,586	-12.7%	3,940,798	+6.0%	0.44%	-1.6%
OM	Sell	OUTSET MED INC	$26,203,718	-61.7%	2,408,430	-23.0%	0.42%	-56.7%
PRVA	Sell	PRIVIA HEALTH GROUP INC	$24,269,094	-17.2%	1,055,178	-6.0%	0.39%	-6.5%
SILK	Buy	SILK RD MED INC	$21,444,124	-51.4%	1,430,562	+5.4%	0.34%	-45.2%
CSTL	Buy	CASTLE BIOSCIENCES INC	$20,741,444	+34.5%	1,228,031	+9.3%	0.33%	+51.8%
LEGN	Buy	LEGEND BIOTECH CORPsponsored ads	$18,683,604	-1.8%	278,154	+0.9%	0.30%	+10.7%
BEAM	Sell	BEAM THERAPEUTICS INC	$16,710,445	-24.7%	694,821	-0.1%	0.27%	-15.1%
SUPN	Sell	SUPERNUS PHARMACEUTICALS INC	$16,007,142	-18.1%	580,600	-10.7%	0.26%	-7.5%
PNT	Buy	POINT BIOPHARMA GLOBAL INC	$15,682,237	+37.8%	2,351,160	+87.2%	0.25%	+56.2%
SRRK	Sell	SCHOLAR ROCK HLDG CORP	$15,179,268	-5.9%	2,137,925	-0.1%	0.24%	+6.5%
INSP	Sell	INSPIRE MED SYS INC	$13,963,826	-88.0%	70,368	-80.3%	0.22%	-86.4%
VRNA	Buy	VERONA PHARMA PLCsponsored ads	$13,958,635	+15.4%	856,358	+49.6%	0.22%	+30.1%
GBIO	Sell	GENERATION BIO CO	$13,708,733	-31.2%	3,617,080	-0.1%	0.22%	-22.2%
AMGN	Buy	AMGEN INC	$13,027,603	+114.9%	48,473	+77.5%	0.21%	+144.2%
REGN	Sell	REGENERON PHARMACEUTICALS	$12,294,199	+4.8%	14,939	-8.5%	0.20%	+18.6%
TXG	Sell	10X GENOMICS INC	$12,145,320	-33.0%	294,432	-9.3%	0.20%	-24.3%
NTRA	Buy	NATERA INC	$11,402,606	+0.7%	257,686	+10.7%	0.18%	+13.6%
RMD	Sell	RESMED INC	$11,341,038	-47.2%	76,696	-22.0%	0.18%	-40.2%
OMCL	Sell	OMNICELL COM	$10,777,126	-50.1%	239,279	-18.4%	0.17%	-43.5%
PHR	Sell	PHREESIA INC	$10,816,449	-45.4%	579,039	-9.3%	0.17%	-38.5%
FATE	Sell	FATE THERAPEUTICS INC	$10,285,347	-55.5%	4,851,579	-0.1%	0.17%	-49.7%
AMED	Sell	AMEDISYS INC	$9,936,546	-53.6%	106,387	-54.6%	0.16%	-47.7%
ILMN	Sell	ILLUMINA INC	$9,888,278	-37.2%	72,030	-14.3%	0.16%	-29.3%
BGNE	Buy	BEIGENE LTDsponsored adr	$9,503,850	+422.6%	53,200	+421.6%	0.15%	+488.5%
DOCS	Sell	DOXIMITY INCcl a	$8,476,478	-44.5%	399,457	-11.0%	0.14%	-37.2%
GILD	Sell	GILEAD SCIENCES INC	$8,044,809	-7.3%	107,350	-4.7%	0.13%	+4.8%
TDOC	Sell	TELADOC HEALTH INC	$6,611,515	-33.4%	355,649	-9.3%	0.11%	-24.6%
MRSN	Sell	MERSANA THERAPEUTICS INC	$6,627,654	-61.4%	5,218,625	-0.0%	0.11%	-56.3%
	New	MOLECULAR TEMPLATES INC	$6,519,794	–	1,031,613	–	0.10%	–
AZN	Sell	ASTRAZENECA PLCsponsored adr	$5,726,045	-6.5%	84,600	-1.2%	0.09%	+5.7%
RDY	Sell	DR REDDYS LABS LTDadr	$5,414,381	-6.4%	80,200	-12.5%	0.09%	+4.8%
BIIB	Sell	BIOGEN INC	$4,449,871	-39.0%	17,314	-32.4%	0.07%	-30.8%
ESPR	Sell	ESPERION THERAPEUTICS INC NE	$4,120,179	-29.6%	4,204,264	-0.1%	0.07%	-20.5%
NVRO	Sell	NEVRO CORP	$3,808,847	-31.4%	198,171	-9.3%	0.06%	-22.8%
JNJ	Buy	JOHNSON & JOHNSON	$3,554,682	+1.2%	22,823	+7.5%	0.06%	+14.0%
OLK	Sell	OLINK HLDG ABsponsored ads	$3,204,526	-28.7%	217,256	-9.3%	0.05%	-18.8%
ABC	Buy	CENCORA INC	$3,075,147	+0.4%	17,087	+7.4%	0.05%	+13.6%
MCK	Buy	MCKESSON CORP	$2,359,061	+67.5%	5,425	+64.6%	0.04%	+90.0%
KOS	Sell	KOSMOS ENERGY LTD	$2,323,120	+21.8%	284,000	-10.8%	0.04%	+37.0%
GH	Sell	GUARDANT HEALTH INC	$2,208,921	-24.9%	74,525	-9.3%	0.04%	-14.3%
BBIO	Sell	BRIDGEBIO PHARMA INC	$2,075,319	+24.5%	78,700	-18.8%	0.03%	+37.5%
VTRS	New	VIATRIS INC	$1,743,721	–	176,848	–	0.03%	–
RYTM	New	RHYTHM PHARMACEUTICALS INC	$1,680,403	–	73,300	–	0.03%	–
PCVX	Buy	VAXCYTE INC	$1,554,890	+19.8%	30,500	+17.3%	0.02%	+31.6%
KRYS	Sell	KRYSTAL BIOTECH INC	$1,450,000	-31.4%	12,500	-30.6%	0.02%	-23.3%
CERT	New	CERTARA INC	$1,331,951	–	91,606	–	0.02%	–
RXRX	New	RECURSION PHARMACEUTICALS INcl a	$1,331,750	–	174,085	–	0.02%	–
AKRO	Sell	AKERO THERAPEUTICS INC	$1,264,500	-0.1%	25,000	-7.7%	0.02%	+11.1%
DVAX	New	DYNAVAX TECHNOLOGIES CORP	$1,228,864	–	83,200	–	0.02%	–
KRTX	Sell	KARUNA THERAPEUTICS INC	$1,166,721	-46.7%	6,900	-31.7%	0.02%	-38.7%
ZTS	Sell	ZOETIS INCcl a	$1,124,259	+0.5%	6,462	-0.5%	0.02%	+12.5%
SPY	Buy	SPDR S&P 500 ETF TRtr unit	$1,111,448	+39.3%	2,600	+44.4%	0.02%	+63.6%
IMCR	New	IMMUNOCORE HLDGS PLCads	$1,030,215	–	19,850	–	0.02%	–
VRDN	Buy	VIRIDIAN THERAPEUTICS INC	$978,232	-7.4%	63,770	+43.6%	0.02%	+6.7%
	New	STRUCTURE THERAPEUTICS INCsponsord ads	$847,056	–	16,800	–	0.01%	–
	New	GE HEALTHCARE TECHNOLOGIES I	$850,500	–	12,500	–	0.01%	–
BCYC	Buy	BICYCLE THERAPEUTICS PLCsponsored ads	$787,528	+23.4%	39,200	+56.8%	0.01%	+44.4%
ABBV	Sell	ABBVIE INC	$709,973	-14.6%	4,763	-22.9%	0.01%	-8.3%
ETNB	Sell	89BIO INC	$605,248	-51.0%	39,200	-39.9%	0.01%	-44.4%
PTGX	New	PROTAGONIST THERAPEUTICS INC	$500,400	–	30,000	–	0.01%	–
PFE	New	PFIZER INC	$316,939	–	9,555	–	0.01%	–
SEER	Sell	SEER INC	$272,771	-53.1%	123,426	-9.3%	0.00%	-50.0%
DGX	Sell	QUEST DIAGNOSTICS INC	$161,343	-40.9%	1,324	-31.8%	0.00%	-25.0%
GRCL	Sell	GRACELL BIOTECHNOLOGIES INCsponsored ads	$109,440	-80.3%	38,000	-73.9%	0.00%	-75.0%
THC	Buy	TENET HEALTHCARE CORP	$46,123	-15.3%	700	+4.6%	0.00%	0.0%
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-10,000	–	0.00%	–
ABCM	Exit	ABCAM PLCads	$0	–	-2,573	–	-0.00%	–
JMIA	Exit	JUMIA TECHNOLOGIES AGsponsored ads	$0	–	-18,000	–	-0.00%	–
VKTX	Exit	VIKING THERAPEUTICS INC	$0	–	-33,000	–	-0.01%	–
ARWR	Exit	ARROWHEAD PHARMACEUTICALS IN	$0	–	-20,700	–	-0.01%	–
	Exit	DICE THERAPEUTICS INC	$0	–	-18,200	–	-0.01%	–
FDMT	Exit	4D MOLECULAR THERAPEUTICS IN	$0	–	-45,000	–	-0.01%	–
RCKT	Exit	ROCKET PHARMACEUTICALS INC	$0	–	-55,600	–	-0.02%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-44,050	–	-0.02%	–
AMWL	Exit	AMERICAN WELL CORPcl a	$0	–	-953,613	–	-0.03%	–
	Exit	SIGHT SCIENCES INC	$0	–	-286,284	–	-0.03%	–
MTEM	Exit	MOLECULAR TEMPLATES INC	$0	–	-11,230,003	–	-0.08%	–
BAX	Exit	BAXTER INTL INC	$0	–	-213,434	–	-0.14%	–

Q2 2023

			Value		Shares		↓ Weighting
VRTX	New	VERTEX PHARMACEUTICALS INC	$386,103,687	–	1,097,166	–	5.51%	–
IONS	New	IONIS PHARMACEUTICALS INC	$384,873,709	–	9,380,300	–	5.49%	–
ARGX	New	ARGENX SEsponsored adr	$359,831,473	–	923,284	–	5.13%	–
ISRG	New	INTUITIVE SURGICAL INC	$287,990,074	–	842,224	–	4.11%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$246,387,040	–	2,612,800	–	3.52%	–
ITCI	New	INTRA-CELLULAR THERAPIES INC	$202,737,976	–	3,201,800	–	2.89%	–
MRNA	New	MODERNA INC	$185,294,669	–	1,525,059	–	2.64%	–
ABT	New	ABBOTT LABS	$179,501,539	–	1,646,501	–	2.56%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$170,879,521	–	899,650	–	2.44%	–
INCY	New	INCYTE CORP	$164,387,621	–	2,640,765	–	2.34%	–
SAGE	New	SAGE THERAPEUTICS INC	$146,437,913	–	3,114,375	–	2.09%	–
SYK	New	STRYKER CORPORATION	$145,511,455	–	476,946	–	2.08%	–
BSX	New	BOSTON SCIENTIFIC CORP	$143,957,939	–	2,661,452	–	2.05%	–
RVMD	New	REVOLUTION MEDICINES INC	$126,955,500	–	4,746,000	–	1.81%	–
MDT	New	MEDTRONIC PLC	$124,264,345	–	1,410,492	–	1.77%	–
INSP	New	INSPIRE MED SYS INC	$115,902,973	–	357,020	–	1.65%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$113,662,320	–	4,013,500	–	1.62%	–
AXNX	New	AXONICS INC	$112,215,907	–	2,223,418	–	1.60%	–
EVH	New	EVOLENT HEALTH INCcl a	$104,484,157	–	3,448,322	–	1.49%	–
UNH	New	UNITEDHEALTH GROUP INC	$100,995,441	–	210,127	–	1.44%	–
PACB	New	PACIFIC BIOSCIENCES CALIF IN	$100,319,626	–	7,542,829	–	1.43%	–
EW	New	EDWARDS LIFESCIENCES CORP	$97,923,218	–	1,038,092	–	1.40%	–
DXCM	New	DEXCOM INC	$97,888,123	–	761,716	–	1.40%	–
EXAS	New	EXACT SCIENCES CORP	$94,535,891	–	1,006,772	–	1.35%	–
PODD	New	INSULET CORP	$93,305,094	–	323,594	–	1.33%	–
BDX	New	BECTON DICKINSON & CO	$89,162,249	–	337,723	–	1.27%	–
PEN	New	PENUMBRA INC	$80,585,733	–	234,220	–	1.15%	–
SWAV	New	SHOCKWAVE MED INC	$77,210,826	–	270,526	–	1.10%	–
OPCH	New	OPTION CARE HEALTH INC	$74,324,871	–	2,287,623	–	1.06%	–
INSM	New	INSMED INC	$69,649,222	–	3,300,911	–	0.99%	–
OM	New	OUTSET MED INC	$68,363,127	–	3,125,886	–	0.98%	–
CRL	New	CHARLES RIV LABS INTL INC	$66,126,358	–	314,513	–	0.94%	–
CLDX	New	CELLDEX THERAPEUTICS INC NEW	$61,074,000	–	1,800,000	–	0.87%	–
ACCD	New	ACCOLADE INC	$60,898,664	–	4,521,059	–	0.87%	–
ALGN	New	ALIGN TECHNOLOGY INC	$60,521,950	–	171,140	–	0.86%	–
IDXX	New	IDEXX LABS INC	$57,475,703	–	114,441	–	0.82%	–
HUM	New	HUMANA INC	$56,952,289	–	127,373	–	0.81%	–
VEEV	New	VEEVA SYS INC	$53,593,926	–	271,046	–	0.76%	–
ARVN	New	ARVINAS INC	$52,792,140	–	2,127,000	–	0.75%	–
RLAY	New	RELAY THERAPEUTICS INC	$52,385,248	–	4,170,800	–	0.75%	–
TMDX	New	TRANSMEDICS GROUP INC	$51,447,240	–	612,613	–	0.73%	–
TNDM	New	TANDEM DIABETES CARE INC	$51,360,600	–	2,092,934	–	0.73%	–
MGNX	New	MACROGENICS INC	$51,413,035	–	9,609,913	–	0.73%	–
BIO	New	BIO RAD LABS INCcl a	$51,004,151	–	134,533	–	0.73%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$50,486,702	–	899,300	–	0.72%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$50,140,697	–	96,101	–	0.72%	–
MOH	New	MOLINA HEALTHCARE INC	$49,505,179	–	164,338	–	0.71%	–
HCA	New	HCA HEALTHCARE INC	$48,713,092	–	160,515	–	0.70%	–
EXEL	New	EXELIXIS INC	$48,424,740	–	2,534,000	–	0.69%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$47,234,895	–	518,495	–	0.67%	–
ANTM	New	ELEVANCE HEALTH INC	$45,518,843	–	102,453	–	0.65%	–
LLY	New	LILLY ELI & CO	$44,625,792	–	95,155	–	0.64%	–
SILK	New	SILK RD MED INC	$44,081,230	–	1,356,763	–	0.63%	–
DHR	New	DANAHER CORPORATION	$44,090,160	–	183,709	–	0.63%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$41,471,976	–	284,835	–	0.59%	–
AXSM	New	AXSOME THERAPEUTICS INC	$41,273,725	–	574,363	–	0.59%	–
BDTX	New	BLACK DIAMOND THERAPEUTICS I	$41,085,987	–	8,135,839	–	0.59%	–
GMED	New	GLOBUS MED INCcl a	$38,560,783	–	647,645	–	0.55%	–
ATRC	New	ATRICURE INC	$36,951,538	–	748,613	–	0.53%	–
IQV	New	IQVIA HLDGS INC	$36,439,712	–	162,120	–	0.52%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$35,799,932	–	288,779	–	0.51%	–
MRK	New	MERCK & CO INC	$35,389,421	–	306,694	–	0.50%	–
COO	New	COOPER COS INC	$33,192,385	–	86,567	–	0.47%	–
CDNA	New	CAREDX INC	$31,590,055	–	3,716,477	–	0.45%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$31,257,155	–	360,604	–	0.45%	–
PRVA	New	PRIVIA HEALTH GROUP INC	$29,312,235	–	1,122,644	–	0.42%	–
	New	PROCEPT BIOROBOTICS CORP	$26,212,626	–	741,517	–	0.37%	–
HOLX	New	HOLOGIC INC	$23,492,312	–	290,136	–	0.34%	–
FATE	New	FATE THERAPEUTICS INC	$23,113,508	–	4,855,779	–	0.33%	–
SRPT	New	SAREPTA THERAPEUTICS INC	$22,929,195	–	200,220	–	0.33%	–
BEAM	New	BEAM THERAPEUTICS INC	$22,204,793	–	695,421	–	0.32%	–
HCM	New	HUTCHMED CHINA LTDsponsored ads	$21,666,996	–	1,805,583	–	0.31%	–
OMCL	New	OMNICELL COM	$21,610,726	–	293,345	–	0.31%	–
RMD	New	RESMED INC	$21,473,088	–	98,275	–	0.31%	–
AMED	New	AMEDISYS INC	$21,426,038	–	234,318	–	0.31%	–
EPIX	New	ESSA PHARMA INC	$21,326,174	–	7,898,583	–	0.30%	–
GBIO	New	GENERATION BIO CO	$19,911,540	–	3,620,280	–	0.28%	–
PHR	New	PHREESIA INC	$19,804,630	–	638,653	–	0.28%	–
CNC	New	CENTENE CORP DEL	$19,730,946	–	292,527	–	0.28%	–
SUPN	New	SUPERNUS PHARMACEUTICALS INC	$19,546,695	–	650,256	–	0.28%	–
LEGN	New	LEGEND BIOTECH CORPsponsored ads	$19,035,299	–	275,754	–	0.27%	–
TXG	New	10X GENOMICS INC	$18,133,817	–	324,746	–	0.26%	–
MRSN	New	MERSANA THERAPEUTICS INC	$17,171,908	–	5,219,425	–	0.24%	–
WVE	New	WAVE LIFE SCIENCES LTD	$16,359,827	–	4,494,458	–	0.23%	–
SRRK	New	SCHOLAR ROCK HLDG CORP	$16,135,789	–	2,140,025	–	0.23%	–
ILMN	New	ILLUMINA INC	$15,754,035	–	84,026	–	0.22%	–
CSTL	New	CASTLE BIOSCIENCES INC	$15,421,870	–	1,124,043	–	0.22%	–
DOCS	New	DOXIMITY INCcl a	$15,260,658	–	448,579	–	0.22%	–
CI	New	THE CIGNA GROUP	$14,141,959	–	50,399	–	0.20%	–
VRNA	New	VERONA PHARMA PLCsponsored ads	$12,098,739	–	572,315	–	0.17%	–
REGN	New	REGENERON PHARMACEUTICALS	$11,731,603	–	16,327	–	0.17%	–
NTRA	New	NATERA INC	$11,326,832	–	232,775	–	0.16%	–
PNT	New	POINT BIOPHARMA GLOBAL INC	$11,381,145	–	1,256,197	–	0.16%	–
TDOC	New	TELADOC HEALTH INC	$9,932,124	–	392,264	–	0.14%	–
BAX	New	BAXTER INTL INC	$9,724,053	–	213,434	–	0.14%	–
GILD	New	GILEAD SCIENCES INC	$8,681,936	–	112,650	–	0.12%	–
BIIB	New	BIOGEN INC	$7,291,590	–	25,598	–	0.10%	–
AZN	New	ASTRAZENECA PLCsponsored adr	$6,126,392	–	85,600	–	0.09%	–
AMGN	New	AMGEN INC	$6,063,366	–	27,310	–	0.09%	–
ESPR	New	ESPERION THERAPEUTICS INC NE	$5,849,487	–	4,208,264	–	0.08%	–
RDY	New	DR REDDYS LABS LTDadr	$5,787,187	–	91,700	–	0.08%	–
NVRO	New	NEVRO CORP	$5,556,126	–	218,573	–	0.08%	–
MTEM	New	MOLECULAR TEMPLATES INC	$5,390,401	–	11,230,003	–	0.08%	–
OLK	New	OLINK HLDG ABsponsored ads	$4,492,950	–	239,624	–	0.06%	–
SGEN	New	SEAGEN INC	$4,234,120	–	22,000	–	0.06%	–
JNJ	New	JOHNSON & JOHNSON	$3,513,162	–	21,225	–	0.05%	–
ABC	New	AMERISOURCEBERGEN CORP	$3,061,561	–	15,910	–	0.04%	–
GH	New	GUARDANT HEALTH INC	$2,942,653	–	82,197	–	0.04%	–
ALKS	New	ALKERMES PLC	$2,557,210	–	81,700	–	0.04%	–
CVS	New	CVS HEALTH CORP	$2,441,257	–	35,314	–	0.04%	–
	New	SIGHT SCIENCES INC	$2,370,432	–	286,284	–	0.03%	–
KRTX	New	KARUNA THERAPEUTICS INC	$2,190,185	–	10,100	–	0.03%	–
KRYS	New	KRYSTAL BIOTECH INC	$2,113,200	–	18,000	–	0.03%	–
AMWL	New	AMERICAN WELL CORPcl a	$2,002,587	–	953,613	–	0.03%	–
KOS	New	KOSMOS ENERGY LTD	$1,906,617	–	318,300	–	0.03%	–
BGNE	New	BEIGENE LTDsponsored adr	$1,818,660	–	10,200	–	0.03%	–
LH	New	LABORATORY CORP AMER HLDGS	$1,686,414	–	6,988	–	0.02%	–
BBIO	New	BRIDGEBIO PHARMA INC	$1,666,680	–	96,900	–	0.02%	–
MCK	New	MCKESSON CORP	$1,408,414	–	3,296	–	0.02%	–
PCVX	New	VAXCYTE INC	$1,298,440	–	26,000	–	0.02%	–
DNLI	New	DENALI THERAPEUTICS INC	$1,299,916	–	44,050	–	0.02%	–
ETNB	New	89BIO INC	$1,235,540	–	65,200	–	0.02%	–
INBX	New	INHIBRX INC	$1,266,848	–	48,800	–	0.02%	–
AKRO	New	AKERO THERAPEUTICS INC	$1,265,299	–	27,100	–	0.02%	–
CYTK	New	CYTOKINETICS INC	$1,210,202	–	37,100	–	0.02%	–
MRUS	New	MERUS N V	$1,171,685	–	44,500	–	0.02%	–
RCKT	New	ROCKET PHARMACEUTICALS INC	$1,104,772	–	55,600	–	0.02%	–
ZTS	New	ZOETIS INCcl a	$1,118,676	–	6,496	–	0.02%	–
VRDN	New	VIRIDIAN THERAPEUTICS INC	$1,056,276	–	44,400	–	0.02%	–
GDX	New	VANECK ETF TRUSTgold miners etf	$993,630	–	33,000	–	0.01%	–
XENE	New	XENON PHARMACEUTICALS INC	$920,150	–	23,900	–	0.01%	–
	New	DICE THERAPEUTICS INC	$845,572	–	18,200	–	0.01%	–
ABBV	New	ABBVIE INC	$831,823	–	6,174	–	0.01%	–
FDMT	New	4D MOLECULAR THERAPEUTICS IN	$813,150	–	45,000	–	0.01%	–
SPY	New	SPDR S&P 500 ETF TRtr unit	$797,904	–	1,800	–	0.01%	–
ARWR	New	ARROWHEAD PHARMACEUTICALS IN	$738,162	–	20,700	–	0.01%	–
	New	VENTYX BIOSCIENCES INC	$803,600	–	24,500	–	0.01%	–
GOOG	New	ALPHABET INCcap stk cl c	$725,820	–	6,000	–	0.01%	–
BCYC	New	BICYCLE THERAPEUTICS PLCsponsored ads	$638,000	–	25,000	–	0.01%	–
VKTX	New	VIKING THERAPEUTICS INC	$534,930	–	33,000	–	0.01%	–
GRCL	New	GRACELL BIOTECHNOLOGIES INCsponsored ads	$554,911	–	145,646	–	0.01%	–
SEER	New	SEER INC	$581,288	–	136,133	–	0.01%	–
XOP	New	SPDR SER TRs&p oilgas exp	$502,437	–	3,900	–	0.01%	–
DGX	New	QUEST DIAGNOSTICS INC	$272,968	–	1,942	–	0.00%	–
MCHI	New	ISHARES TRmsci china etf	$183,434	–	4,100	–	0.00%	–
GDXJ	New	VANECK ETF TRUSTjunior gold mine	$178,300	–	5,000	–	0.00%	–
TSM	New	TAIWAN SEMICONDUCTOR MFG LTDsponsored ads	$109,902	–	1,089	–	0.00%	–
ABCM	New	ABCAM PLCads	$62,961	–	2,573	–	0.00%	–
THC	New	TENET HEALTHCARE CORP	$54,443	–	669	–	0.00%	–
JMIA	New	JUMIA TECHNOLOGIES AGsponsored ads	$61,560	–	18,000	–	0.00%	–
ASR	New	GRUPO AEROPORTUARIO DEL SUREspon adr ser b	$37,488	–	135	–	0.00%	–
KZR	New	KEZAR LIFE SCIENCES INC	$24,500	–	10,000	–	0.00%	–
EQIX	New	EQUINIX INC	$31,358	–	40	–	0.00%	–
EVTC	New	EVERTEC INC	$27,217	–	739	–	0.00%	–
UMC	New	UNITED MICROELECTRONICS CORPspon adr new	$21,287	–	2,698	–	0.00%	–
INFY	New	INFOSYS LTDsponsored adr	$18,159	–	1,130	–	0.00%	–

Q4 2022

			Value		Shares		↓ Weighting
ASR	Exit	GRUPO AEROPORTUARIO DEL SUREspon adr ser b	$0	–	-135	–	0.00%	–
EQIX	Exit	EQUINIX INC	$0	–	-40	–	0.00%	–
CTLT	Exit	CATALENT INC	$0	–	-473	–	0.00%	–
UMC	Exit	UNITED MICROELECTRONICS CORPspon adr new	$0	–	-2,698	–	0.00%	–
INFY	Exit	INFOSYS LTDsponsored adr	$0	–	-1,130	–	0.00%	–
NVST	Exit	ENVISTA HOLDINGS CORP	$0	–	-822	–	0.00%	–
EVTC	Exit	EVERTEC INC	$0	–	-739	–	0.00%	–
DLB	Exit	DOLBY LABORATORIES INC	$0	–	-1,600	–	-0.00%	–
CAH	Exit	CARDINAL HEALTH INC	$0	–	-918	–	-0.00%	–
ACHC	Exit	ACADIA HEALTHCARE COMPANY IN	$0	–	-906	–	-0.00%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-14,800	–	-0.00%	–
TSM	Exit	TAIWAN SEMICONDUCTOR MFG LTDsponsored ads	$0	–	-770	–	-0.00%	–
ZTS	Exit	ZOETIS INCcl a	$0	–	-246	–	-0.00%	–
UTHR	Exit	UNITED THERAPEUTICS CORP	$0	–	-301	–	-0.00%	–
IPGP	Exit	IPG PHOTONICS CORP	$0	–	-1,050	–	-0.00%	–
MELI	Exit	MERCADOLIBRE INC	$0	–	-170	–	-0.00%	–
MKTX	Exit	MARKETAXESS HOLDINGS INC	$0	–	-662	–	-0.00%	–
GDXJ	Exit	VANECK ETF TRUSTjunior gold mine	$0	–	-5,000	–	-0.00%	–
AVLR	Exit	AVALARA INC	$0	–	-1,300	–	-0.00%	–
MCHI	Exit	ISHARES TRmsci china etf	$0	–	-4,100	–	-0.00%	–
JMIA	Exit	JUMIA TECHNOLOGIES AGsponsored ads	$0	–	-18,000	–	-0.00%	–
SWKS	Exit	SKYWORKS SOLUTIONS INC	$0	–	-2,100	–	-0.00%	–
EL	Exit	ESTEE LAUDER COMPANIEScl a	$0	–	-1,348	–	-0.00%	–
OPT	Exit	OPTHEA LTDsponsored ads	$0	–	-47,000	–	-0.00%	–
GDX	Exit	VANECK ETF TRUSTgold miners etf	$0	–	-13,400	–	-0.01%	–
MRK	Exit	MERCK & CO. INC.	$0	–	-4,844	–	-0.01%	–
BMY	Exit	BRISTOL-MYERS SQUIBB CO	$0	–	-7,062	–	-0.01%	–
MRUS	Exit	MERUS NV	$0	–	-25,400	–	-0.01%	–
XOP	Exit	SPDR S&P SER TRs&p oilgas exp	$0	–	-3,900	–	-0.01%	–
DSGN	Exit	DESIGN THERAPEUTICS INC	$0	–	-34,881	–	-0.01%	–
GOOG	Exit	ALPHABET INCcap stk cl c	$0	–	-6,000	–	-0.01%	–
XNCR	Exit	XENCOR INC	$0	–	-25,400	–	-0.01%	–
SPY	Exit	SPDR S&P 500 ETF TRUSTtr unit	$0	–	-1,800	–	-0.01%	–
	Exit	CARIBOU BIOSCIENCES INC	$0	–	-66,300	–	-0.01%	–
RDY	Exit	DR. REDDYS LABS LTDadr	$0	–	-12,400	–	-0.01%	–
INBX	Exit	INHIBRX INC	$0	–	-43,500	–	-0.01%	–
LH	Exit	LABORATORY CRP OF AMER HLDGS	$0	–	-3,900	–	-0.01%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-7,000	–	-0.01%	–
DNLI	Exit	DENALI THERAPEUTICS INC	$0	–	-31,000	–	-0.01%	–
MCK	Exit	MCKESSON CORP	$0	–	-2,938	–	-0.01%	–
VRDN	Exit	VIRIDIAN THERAPEUTICS INC	$0	–	-46,100	–	-0.01%	–
A	Exit	AGILENT TECHNOLOGIES INC	$0	–	-8,627	–	-0.02%	–
SEER	Exit	SEER INC	$0	–	-136,133	–	-0.02%	–
BLI	Exit	BERKELEY LTS INC	$0	–	-385,014	–	-0.02%	–
RGEN	Exit	REPLIGEN CORP	$0	–	-6,600	–	-0.02%	–
KRYS	Exit	KRYSTAL BIOTECH INC	$0	–	-18,300	–	-0.02%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-36,600	–	-0.02%	–
AKRO	Exit	AKERO THERAPEUTICS INC	$0	–	-41,634	–	-0.02%	–
NPCE	Exit	NEUROPACE INC	$0	–	-388,368	–	-0.02%	–
ABC	Exit	AMERISOURCEBERGEN CORP	$0	–	-11,910	–	-0.02%	–
KOS	Exit	KOSMOS ENERGY LTD	$0	–	-318,300	–	-0.02%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-30,478	–	-0.02%	–
	Exit	SIGHT SCIENCES INC	$0	–	-294,606	–	-0.03%	–
RLMD	Exit	RELMADA THERAPEUTICS INC	$0	–	-53,187	–	-0.03%	–
RCUS	Exit	ARCUS BIOSCIENCES INC	$0	–	-83,500	–	-0.03%	–
BCYC	Exit	BICYCLE THERAPEUTICS PLCsponsored ads	$0	–	-98,100	–	-0.03%	–
ABBV	Exit	ABBVIE INC	$0	–	-16,997	–	-0.03%	–
AZN	Exit	ASTRAZENECA PLCsponsored adr	$0	–	-44,400	–	-0.04%	–
FIXX	Exit	HOMOLOGY MEDICINES INC	$0	–	-1,622,522	–	-0.04%	–
OLK	Exit	OLINK HOLDING ABsponsored ads	$0	–	-230,522	–	-0.04%	–
LUNG	Exit	PULMONX CORP	$0	–	-173,336	–	-0.04%	–
LLY	Exit	ELI LILLY & CO	$0	–	-9,490	–	-0.04%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-62,083	–	-0.05%	–
CYTK	Exit	CYTOKINETICS INC	$0	–	-71,200	–	-0.05%	–
SUPN	Exit	SUPERNUS PHARMACEUTICALS INC	$0	–	-119,278	–	-0.06%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-53,493	–	-0.06%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-30,671	–	-0.07%	–
DOCS	Exit	DOXIMITY INCcl a	$0	–	-193,439	–	-0.08%	–
SGEN	Exit	SEAGEN INC	$0	–	-42,926	–	-0.08%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-97,854	–	-0.09%	–
TFX	Exit	TELEFLEX INC	$0	–	-31,480	–	-0.09%	–
AMWL	Exit	AMERICAN WELL CORPcl a	$0	–	-1,769,703	–	-0.09%	–
TXG	Exit	10X GENOMICS INC	$0	–	-254,134	–	-0.10%	–
BIIB	Exit	BIOGEN INC	$0	–	-28,735	–	-0.11%	–
BDTX	Exit	BLACK DIAMOND THERAPEUTICS I	$0	–	-4,717,113	–	-0.11%	–
MTEM	Exit	MOLECULAR TEMPLATES INC	$0	–	-11,278,003	–	-0.12%	–
AVTR	Exit	AVANTOR INC	$0	–	-503,007	–	-0.14%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-390,286	–	-0.14%	–
AMGN	Exit	AMGEN INC	$0	–	-45,196	–	-0.15%	–
EPIX	Exit	ESSA PHARMA INC	$0	–	-5,898,583	–	-0.15%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-17,389	–	-0.17%	–
NVRO	Exit	NEVRO CORP	$0	–	-260,835	–	-0.17%	–
SRRK	Exit	SCHOLAR ROCK HOLDING CORP	$0	–	-2,152,025	–	-0.21%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-74,939	–	-0.22%	–
HCM	Exit	HUTCHMED CHINA LTDsponsored ads	$0	–	-1,758,075	–	-0.23%	–
HOLX	Exit	HOLOGIC INC	$0	–	-251,412	–	-0.23%	–
WVE	Exit	WAVE LIFE SCIENCES LTD	$0	–	-4,494,458	–	-0.23%	–
ILMN	Exit	ILLUMINA INC	$0	–	-85,927	–	-0.24%	–
PHR	Exit	PHREESIA INC	$0	–	-666,419	–	-0.24%	–
BAX	Exit	BAXTER INTL INC	$0	–	-319,548	–	-0.25%	–
PRVA	Exit	PRIVIA HEALTH GROUP INC	$0	–	-515,030	–	-0.25%	–
RMD	Exit	RESMED INC	$0	–	-84,612	–	-0.26%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB L	$0	–	-301,850	–	-0.27%	–
GBIO	Exit	GENERATION BIO CO	$0	–	-3,627,280	–	-0.28%	–
BNTX	Exit	BIONTECH SEsponsored ads	$0	–	-153,580	–	-0.30%	–
AUPH	Exit	AURINIA PHARMACEUTICALS INC	$0	–	-2,846,457	–	-0.31%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-225,114	–	-0.31%	–
COO	Exit	COOPER COS INC	$0	–	-81,313	–	-0.31%	–
AXSM	Exit	AXSOME THERAPEUTICS INC	$0	–	-496,524	–	-0.32%	–
ADPT	Exit	ADAPTIVE BIOTECHNOLOGIES	$0	–	-3,279,620	–	-0.34%	–
	Exit	PROCEPT BIOROBOTICS CORP	$0	–	-589,262	–	-0.35%	–
CSTL	Exit	CASTLE BIOSCIENCES INC	$0	–	-941,871	–	-0.35%	–
ATRC	Exit	ATRICURE INC	$0	–	-642,447	–	-0.36%	–
MGNX	Exit	MACROGENICS INC	$0	–	-7,325,514	–	-0.36%	–
LEGN	Exit	LEGEND BIOTECH CORPsponsored ads	$0	–	-625,461	–	-0.37%	–
VEEV	Exit	VEEVA SYSTEMS INC	$0	–	-157,591	–	-0.37%	–
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-3,031,000	–	-0.38%	–
BEAM	Exit	BEAM THERAPEUTICS INC	$0	–	-571,721	–	-0.39%	–
TMDX	Exit	TRANSMEDICS GROUP INC	$0	–	-653,814	–	-0.39%	–
MRSN	Exit	MERSANA THERAPEUTICS INC	$0	–	-4,082,600	–	-0.40%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-265,270	–	-0.40%	–
ESPR	Exit	ESPERION THERAPEUTICS INC	$0	–	-4,225,264	–	-0.41%	–
IQV	Exit	IQVIA HOLDINGS INC	$0	–	-160,227	–	-0.42%	–
HRMY	Exit	HARMONY BIOSCIENCES HOLDINGS	$0	–	-657,188	–	-0.42%	–
PACB	Exit	PACIFIC BIOSCIENCES OF CALIF	$0	–	-5,439,551	–	-0.45%	–
PFE	Exit	PFIZER INC	$0	–	-767,300	–	-0.48%	–
IDXX	Exit	IDEXX LABORATORIES INC	$0	–	-108,822	–	-0.51%	–
PEN	Exit	PENUMBRA INC	$0	–	-189,774	–	-0.52%	–
OMCL	Exit	OMNICELL INC	$0	–	-414,284	–	-0.52%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-72,144	–	-0.52%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-1,129,653	–	-0.53%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-930,500	–	-0.53%	–
GMED	Exit	GLOBUS MEDICAL INCcl a	$0	–	-647,163	–	-0.55%	–
OM	Exit	OUTSET MEDICAL INC	$0	–	-2,417,456	–	-0.55%	–
ACCD	Exit	ACCOLADE INC	$0	–	-3,571,870	–	-0.58%	–
ABMD	Exit	ABIOMED INC	$0	–	-166,355	–	-0.59%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-528,440	–	-0.59%	–
EXEL	Exit	EXELIXIS INC	$0	–	-2,673,500	–	-0.60%	–
BIO	Exit	BIO RAD LABS INCcl a	$0	–	-101,818	–	-0.61%	–
CDNA	Exit	CAREDX INC	$0	–	-2,601,446	–	-0.64%	–
SILK	Exit	SILK ROAD MEDICAL INC	$0	–	-1,047,356	–	-0.68%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-615,926	–	-0.71%	–
CLDX	Exit	CELLDEX THERAPEUTICS INC	$0	–	-1,800,000	–	-0.73%	–
CRL	Exit	CHARLES RIV LABS INC	$0	–	-262,993	–	-0.74%	–
CI	Exit	CIGNA CORP NEW	$0	–	-188,701	–	-0.75%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-285,789	–	-0.75%	–
AMED	Exit	AMEDISYS INC	$0	–	-598,934	–	-0.83%	–
CRSP	Exit	CRISPR THERAPEUTICS AGnamen akt	$0	–	-928,305	–	-0.87%	–
HUM	Exit	HUMANA INC	$0	–	-134,206	–	-0.94%	–
EVH	Exit	EVOLENT HEALTH INCcl a	$0	–	-1,869,055	–	-0.96%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-1,007,444	–	-0.99%	–
INSM	Exit	INSMED INC	$0	–	-3,214,704	–	-0.99%	–
DXCM	Exit	DEXCOM INC	$0	–	-860,460	–	-1.00%	–
INSP	Exit	INSPIRE MEDICAL SYSTEMS INC	$0	–	-401,768	–	-1.02%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-334,838	–	-1.07%	–
TNDM	Exit	TANDEM DIABETES CARE INC	$0	–	-1,566,015	–	-1.08%	–
SWAV	Exit	SHOCKWAVE MEDICAL INC	$0	–	-276,132	–	-1.10%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-240,590	–	-1.14%	–
OPCH	Exit	OPTION CARE HEALTH INC	$0	–	-2,629,172	–	-1.19%	–
SRPT	Exit	SAREPTA THERAPEUTICS INC	$0	–	-755,898	–	-1.20%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-3,746,086	–	-1.20%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-1,025,715	–	-1.22%	–
PODD	Exit	INSULET CORP	$0	–	-373,953	–	-1.23%	–
ANTM	Exit	ELEVANCE HEALTH INC	$0	–	-202,492	–	-1.32%	–
RVMD	Exit	REVOLUTION MEDICINES INC	$0	–	-4,680,162	–	-1.32%	–
RLAY	Exit	RELAY THERAPEUTICS INC	$0	–	-4,204,820	–	-1.35%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-367,435	–	-1.36%	–
SYK	Exit	STRYKER CORPORATION	$0	–	-476,932	–	-1.39%	–
ARVN	Exit	ARVINAS INC	$0	–	-2,190,762	–	-1.40%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-5,912,639	–	-1.52%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-823,839	–	-1.58%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-4,058,792	–	-1.65%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-2,970,678	–	-1.67%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-3,804,047	–	-2.11%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-296,754	–	-2.15%	–
ABT	Exit	ABBOTT LABS	$0	–	-1,569,851	–	-2.18%	–
AXNX	Exit	AXONICS INC	$0	–	-2,193,200	–	-2.22%	–
ITCI	Exit	INTRA-CELLULAR THERAPIES INC	$0	–	-3,329,279	–	-2.22%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-898,092	–	-2.42%	–
INCY	Exit	INCYTE CORP	$0	–	-2,744,277	–	-2.62%	–
MRNA	Exit	MODERNA INC	$0	–	-1,559,801	–	-2.65%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-956,762	–	-2.75%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-2,855,146	–	-4.35%	–
ARGX	Exit	ARGENX SEsponsored adr	$0	–	-919,346	–	-4.76%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-1,158,126	–	-4.81%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-9,463,400	–	-6.01%	–

Q3 2022

			Value		Shares		↓ Weighting
IONS	Sell	IONIS PHARMACEUTICALS INC	$418,566,000	+15.6%	9,463,400	-3.2%	6.01%	+17.4%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$335,323,000	+1.2%	1,158,126	-1.5%	4.81%	+2.7%
ARGX	Sell	ARGENX SEsponsored adr	$331,858,000	-5.1%	919,346	-1.5%	4.76%	-3.6%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$303,245,000	+9.4%	2,855,146	+0.4%	4.35%	+11.0%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$191,505,000	+24.1%	956,762	-9.6%	2.75%	+25.9%
MRNA	Sell	MODERNA INC	$184,447,000	-18.1%	1,559,801	-1.1%	2.65%	-16.9%
INCY	Sell	INCYTE CORP	$182,878,000	-13.2%	2,744,277	-1.0%	2.62%	-11.9%
ISRG	Sell	INTUITIVE SURGICAL INC	$168,338,000	-7.8%	898,092	-1.2%	2.42%	-6.4%
ITCI	Sell	INTRA-CELLULAR THERAPIES INC	$154,912,000	-19.0%	3,329,279	-0.6%	2.22%	-17.8%
AXNX	Sell	AXONICS INC	$154,489,000	+17.8%	2,193,200	-5.2%	2.22%	+19.6%
ABT	Sell	ABBOTT LABS	$151,899,000	-11.2%	1,569,851	-0.3%	2.18%	-9.8%
UNH	Sell	UNITEDHEALTH GROUP INC	$149,873,000	-3.4%	296,754	-1.8%	2.15%	-1.9%
BSX	Sell	BOSTON SCIENTIFIC CORP	$147,331,000	+2.7%	3,804,047	-1.2%	2.11%	+4.2%
SAGE	Sell	SAGE THERAPEUTICS INC	$116,332,000	+21.1%	2,970,678	-0.1%	1.67%	+23.0%
AGIO	Sell	AGIOS PHARMACEUTICALS INC	$114,783,000	+27.4%	4,058,792	-0.1%	1.65%	+29.4%
JAZZ	Sell	JAZZ PHARMACEUTICALS PLC	$109,810,000	-23.3%	823,839	-10.2%	1.58%	-22.1%
MYOV	Sell	MYOVANT SCIENCES LTD	$106,191,000	+44.3%	5,912,639	-0.1%	1.52%	+46.5%
ARVN	Buy	ARVINAS INC	$97,467,000	+9.0%	2,190,762	+3.1%	1.40%	+10.7%
SYK	Sell	STRYKER CORPORATION	$96,598,000	+1.7%	476,932	-0.1%	1.39%	+3.2%
DHR	Buy	DANAHER CORPORATION	$94,905,000	+2.8%	367,435	+0.9%	1.36%	+4.4%
RLAY	Buy	RELAY THERAPEUTICS INC	$94,062,000	+39.3%	4,204,820	+4.3%	1.35%	+41.4%
RVMD	Buy	REVOLUTION MEDICINES INC	$92,293,000	+40.0%	4,680,162	+38.3%	1.32%	+42.2%
ANTM	Sell	ELEVANCE HEALTH INC	$91,979,000	-8.6%	202,492	-2.9%	1.32%	-7.2%
PODD	Sell	INSULET CORP	$85,785,000	+1.9%	373,953	-3.2%	1.23%	+3.4%
EW	Buy	EDWARDS LIFESCIENCES CORP	$84,755,000	-11.8%	1,025,715	+1.5%	1.22%	-10.5%
FATE	Buy	FATE THERAPEUTICS INC	$83,950,000	-4.6%	3,746,086	+5.5%	1.20%	-3.1%
SRPT	Sell	SAREPTA THERAPEUTICS INC	$83,557,000	-2.2%	755,898	-33.7%	1.20%	-0.7%
OPCH	Sell	OPTION CARE HEALTH INC	$82,740,000	+3.1%	2,629,172	-8.9%	1.19%	+4.7%
MOH	Sell	MOLINA HEALTHCARE INC	$79,356,000	+14.3%	240,590	-3.1%	1.14%	+16.1%
SWAV	Sell	SHOCKWAVE MEDICAL INC	$76,784,000	+8.3%	276,132	-25.5%	1.10%	+10.0%
TNDM	Buy	TANDEM DIABETES CARE INC	$74,933,000	-3.8%	1,566,015	+19.0%	1.08%	-2.4%
BDX	Sell	BECTON DICKINSON & CO	$74,612,000	-11.8%	334,838	-2.4%	1.07%	-10.4%
INSP	Sell	INSPIRE MEDICAL SYSTEMS INC	$71,262,000	-4.2%	401,768	-1.3%	1.02%	-2.7%
DXCM	Sell	DEXCOM INC	$69,301,000	+0.1%	860,460	-7.3%	1.00%	+1.7%
INSM	Sell	INSMED INC	$69,245,000	-3.0%	3,214,704	-11.2%	0.99%	-1.6%
APLS	Sell	APELLIS PHARMACEUTICALS INC	$68,809,000	+26.1%	1,007,444	-16.5%	0.99%	+28.1%
EVH	Sell	EVOLENT HEALTH INCcl a	$67,155,000	+8.3%	1,869,055	-7.4%	0.96%	+10.0%
HUM	Sell	HUMANA INC	$65,115,000	-4.3%	134,206	-7.6%	0.94%	-2.7%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$60,664,000	+8.3%	928,305	+0.7%	0.87%	+10.0%
AMED	Buy	AMEDISYS INC	$57,971,000	-5.8%	598,934	+2.4%	0.83%	-4.4%
HCA	Sell	HCA HEALTHCARE INC	$52,525,000	+6.8%	285,789	-2.4%	0.75%	+8.3%
CI	Sell	CIGNA CORP NEW	$52,359,000	+2.6%	188,701	-2.6%	0.75%	+4.2%
CRL	Buy	CHARLES RIV LABS INC	$51,757,000	+4.7%	262,993	+13.8%	0.74%	+6.3%
CLDX	Buy	CELLDEX THERAPEUTICS INC	$50,598,000	+102.9%	1,800,000	+94.6%	0.73%	+105.7%
MDT	Sell	MEDTRONIC PLC	$49,736,000	-14.2%	615,926	-4.6%	0.71%	-12.8%
SILK	Buy	SILK ROAD MEDICAL INC	$47,131,000	+23.7%	1,047,356	+0.0%	0.68%	+25.4%
CDNA	Buy	CAREDX INC	$44,277,000	-18.8%	2,601,446	+2.5%	0.64%	-17.5%
BIO	Buy	BIO RAD LABS INCcl a	$42,472,000	-5.9%	101,818	+11.7%	0.61%	-4.4%
EXEL	Sell	EXELIXIS INC	$41,921,000	-24.8%	2,673,500	-0.2%	0.60%	-23.6%
CNC	Sell	CENTENE CORP DEL	$41,118,000	-11.0%	528,440	-3.2%	0.59%	-9.6%
ABMD	Sell	ABIOMED INC	$40,867,000	-2.6%	166,355	-1.9%	0.59%	-1.0%
ACCD	Sell	ACCOLADE INC	$40,790,000	+51.6%	3,571,870	-1.7%	0.58%	+53.9%
OM	Buy	OUTSET MEDICAL INC	$38,510,000	+11.4%	2,417,456	+3.9%	0.55%	+13.1%
GMED	Sell	GLOBUS MEDICAL INCcl a	$38,551,000	+4.6%	647,163	-1.4%	0.55%	+6.1%
HALO	Sell	HALOZYME THERAPEUTICS INC	$36,792,000	-13.9%	930,500	-4.2%	0.53%	-12.6%
EXAS	Buy	EXACT SCIENCES CORP	$36,702,000	+22.9%	1,129,653	+49.0%	0.53%	+24.9%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$36,591,000	-6.2%	72,144	+0.5%	0.52%	-4.9%
OMCL	Sell	OMNICELL INC	$36,055,000	-25.6%	414,284	-2.7%	0.52%	-24.5%
PEN	Sell	PENUMBRA INC	$35,981,000	+50.0%	189,774	-1.5%	0.52%	+52.2%
IDXX	Sell	IDEXX LABORATORIES INC	$35,454,000	-12.7%	108,822	-6.0%	0.51%	-11.3%
PFE	Sell	PFIZER INC	$33,577,000	-23.4%	767,300	-8.2%	0.48%	-22.1%
PACB	Sell	PACIFIC BIOSCIENCES OF CALIF	$31,577,000	+19.8%	5,439,551	-8.8%	0.45%	+21.8%
HRMY	Sell	HARMONY BIOSCIENCES HOLDINGS	$29,107,000	-15.0%	657,188	-6.4%	0.42%	-13.6%
IQV	Sell	IQVIA HOLDINGS INC	$29,024,000	-20.7%	160,227	-5.0%	0.42%	-19.3%
ESPR	Sell	ESPERION THERAPEUTICS INC	$28,309,000	+5.1%	4,225,264	-0.2%	0.41%	+6.6%
ZBH	Sell	ZIMMER BIOMET HOLDINGS INC	$27,734,000	-0.8%	265,270	-0.3%	0.40%	+0.8%
MRSN	Buy	MERSANA THERAPEUTICS INC	$27,599,000	+53.4%	4,082,600	+4.8%	0.40%	+55.9%
TMDX	Buy	TRANSMEDICS GROUP INC	$27,290,000	+49.6%	653,814	+12.7%	0.39%	+51.9%
BEAM	Sell	BEAM THERAPEUTICS INC	$27,237,000	+22.9%	571,721	-0.2%	0.39%	+24.9%
KZR	Sell	KEZAR LIFE SCIENCES INC	$26,097,000	+4.0%	3,031,000	-0.1%	0.38%	+5.6%
VEEV	Sell	VEEVA SYSTEMS INC	$25,984,000	-22.3%	157,591	-6.6%	0.37%	-21.0%
LEGN	Sell	LEGEND BIOTECH CORPsponsored ads	$25,519,000	-26.4%	625,461	-0.8%	0.37%	-25.3%
ATRC	Buy	ATRICURE INC	$25,120,000	-4.2%	642,447	+0.1%	0.36%	-2.7%
CSTL	Buy	CASTLE BIOSCIENCES INC	$24,564,000	+18.9%	941,871	+0.1%	0.35%	+20.9%
	Sell	PROCEPT BIOROBOTICS CORP	$24,431,000	+25.5%	589,262	-1.0%	0.35%	+27.6%
ADPT	Sell	ADAPTIVE BIOTECHNOLOGIES	$23,351,000	-18.4%	3,279,620	-7.3%	0.34%	-17.3%
AXSM	Sell	AXSOME THERAPEUTICS INC	$22,155,000	-29.2%	496,524	-39.2%	0.32%	-28.1%
CVS	Sell	CVS HEALTH CORP	$21,469,000	+1.1%	225,114	-1.8%	0.31%	+2.7%
COO	Sell	COOPER COS INC	$21,459,000	-15.9%	81,313	-0.2%	0.31%	-14.7%
AUPH	Buy	AURINIA PHARMACEUTICALS INC	$21,405,000	-20.3%	2,846,457	+6.6%	0.31%	-19.2%
BNTX	Buy	BIONTECH SEsponsored ads	$20,715,000	-8.1%	153,580	+1.6%	0.30%	-6.9%
HZNP	Sell	HORIZON THERAPEUTICS PUB L	$18,681,000	-30.6%	301,850	-10.5%	0.27%	-29.5%
RMD	Sell	RESMED INC	$18,471,000	+3.8%	84,612	-0.3%	0.26%	+5.6%
PRVA	Sell	PRIVIA HEALTH GROUP INC	$17,542,000	+15.9%	515,030	-0.9%	0.25%	+17.8%
BAX	Sell	BAXTER INTL INC	$17,211,000	-41.5%	319,548	-30.2%	0.25%	-40.6%
PHR	Sell	PHREESIA INC	$16,980,000	-0.2%	666,419	-2.0%	0.24%	+1.7%
ILMN	Sell	ILLUMINA INC	$16,394,000	+2.4%	85,927	-1.1%	0.24%	+4.0%
HOLX	Sell	HOLOGIC INC	$16,221,000	-13.6%	251,412	-7.2%	0.23%	-12.1%
HCM	Buy	HUTCHMED CHINA LTDsponsored ads	$15,947,000	-25.3%	1,758,075	+0.1%	0.23%	-24.2%
ALGN	Sell	ALIGN TECHNOLOGY INC	$15,521,000	-51.5%	74,939	-44.6%	0.22%	-50.7%
NVRO	Sell	NEVRO CORP	$12,155,000	+4.5%	260,835	-1.7%	0.17%	+6.1%
REGN	Sell	REGENERON PHARMACEUTICALS	$11,979,000	+14.3%	17,389	-1.9%	0.17%	+16.2%
EPIX	Buy	ESSA PHARMA INC	$10,736,000	-32.0%	5,898,583	+17.7%	0.15%	-30.9%
AMGN	Sell	AMGEN INC	$10,187,000	-17.8%	45,196	-11.3%	0.15%	-16.6%
TDOC	Sell	TELADOC HEALTH INC	$9,894,000	-28.4%	390,286	-6.2%	0.14%	-27.2%
BIIB	Buy	BIOGEN INC	$7,672,000	+72.2%	28,735	+31.5%	0.11%	+74.6%
TXG	Sell	10X GENOMICS INC	$7,238,000	-38.3%	254,134	-2.0%	0.10%	-37.3%
TFX	Sell	TELEFLEX INC	$6,342,000	-73.1%	31,480	-67.2%	0.09%	-72.8%
GILD	Buy	GILEAD SCIENCES INC	$6,037,000	+29.5%	97,854	+29.7%	0.09%	+31.8%
DOCS	Buy	DOXIMITY INCcl a	$5,846,000	+23.2%	193,439	+41.9%	0.08%	+25.4%
SGEN	Sell	SEAGEN INC	$5,874,000	-32.8%	42,926	-13.1%	0.08%	-32.3%
JNJ	Buy	JOHNSON & JOHNSON	$5,010,000	-2.4%	30,671	+6.1%	0.07%	-1.4%
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$4,535,000	-25.8%	53,493	-27.5%	0.06%	-24.4%
SUPN	Buy	SUPERNUS PHARMACEUTICALS INC	$4,038,000	+69.5%	119,278	+44.8%	0.06%	+70.6%
CYTK	Buy	CYTOKINETICS INC	$3,450,000	+32.2%	71,200	+7.2%	0.05%	+35.1%
GH	Sell	GUARDANT HEALTH INC	$3,342,000	+17.4%	62,083	-12.0%	0.05%	+20.0%
LLY	Buy	ELI LILLY & CO	$3,069,000	+877.4%	9,490	+879.4%	0.04%	+1000.0%
OLK	Sell	OLINK HOLDING ABsponsored ads	$2,799,000	-21.7%	230,522	-2.0%	0.04%	-21.6%
AZN	Sell	ASTRAZENECA PLCsponsored adr	$2,457,000	-57.3%	44,400	-49.0%	0.04%	-56.8%
ABBV	Buy	ABBVIE INC	$2,281,000	+1739.5%	16,997	+2003.6%	0.03%	+1550.0%
BCYC	Buy	BICYCLE THERAPEUTICS PLCsponsored ads	$2,282,000	+61.2%	98,100	+16.2%	0.03%	+65.0%
RCUS	Sell	ARCUS BIOSCIENCES INC	$2,184,000	-4.3%	83,500	-7.3%	0.03%	-3.1%
RLMD	Buy	RELMADA THERAPEUTICS INC	$1,969,000	+196.1%	53,187	+52.0%	0.03%	+211.1%
NTLA	Buy	INTELLIA THERAPEUTICS INC	$1,706,000	+108.8%	30,478	+93.0%	0.02%	+100.0%
ABC	Sell	AMERISOURCEBERGEN CORP	$1,612,000	-12.3%	11,910	-8.4%	0.02%	-11.5%
NPCE	Sell	NEUROPACE INC	$1,456,000	-42.1%	388,368	-23.5%	0.02%	-41.7%
AKRO	New	AKERO THERAPEUTICS INC	$1,418,000	–	41,634	–	0.02%	–
RGEN	New	REPLIGEN CORP	$1,235,000	–	6,600	–	0.02%	–
ZLAB	New	ZAI LAB LTDadr	$1,278,000	–	36,600	–	0.02%	–
KRYS	Buy	KRYSTAL BIOTECH INC	$1,276,000	+45.0%	18,300	+36.6%	0.02%	+50.0%
A	New	AGILENT TECHNOLOGIES INC	$1,049,000	–	8,627	–	0.02%	–
VRDN	Sell	VIRIDIAN THERAPEUTICS INC	$946,000	+66.8%	46,100	-5.9%	0.01%	+75.0%
DNLI	New	DENALI THERAPEUTICS INC	$951,000	–	31,000	–	0.01%	–
MCK	Buy	MCKESSON CORP	$999,000	+20.7%	2,938	+15.8%	0.01%	+16.7%
BGNE	New	BEIGENE LTDsponsored adr	$940,000	–	7,000	–	0.01%	–
LH	Sell	LABORATORY CRP OF AMER HLDGS	$799,000	-19.8%	3,900	-8.2%	0.01%	-21.4%
INBX	Sell	INHIBRX INC	$781,000	-10.1%	43,500	-43.2%	0.01%	-8.3%
	Sell	CARIBOU BIOSCIENCES INC	$699,000	+83.0%	66,300	-5.7%	0.01%	+100.0%
XNCR	Sell	XENCOR INC	$660,000	-9.0%	25,400	-4.2%	0.01%	-10.0%
SPY	New	SPDR S&P 500 ETF TRUSTtr unit	$643,000	–	1,800	–	0.01%	–
DSGN	New	DESIGN THERAPEUTICS INC	$583,000	–	34,881	–	0.01%	–
GOOG	Buy	ALPHABET INCcap stk cl c	$577,000	-12.0%	6,000	+1900.0%	0.01%	-11.1%
BMY	Sell	BRISTOL-MYERS SQUIBB CO	$502,000	-73.8%	7,062	-71.6%	0.01%	-74.1%
MRUS	New	MERUS NV	$509,000	–	25,400	–	0.01%	–
XOP	New	SPDR S&P SER TRs&p oilgas exp	$486,000	–	3,900	–	0.01%	–
MRK	Buy	MERCK & CO. INC.	$417,000	+373.9%	4,844	+402.5%	0.01%	+500.0%
ACHC	New	ACADIA HEALTHCARE COMPANY IN	$71,000	–	906	–	0.00%	–
NKTR	Sell	NEKTAR THERAPEUTICS	$47,000	-56.9%	14,800	-48.6%	0.00%	-50.0%
CAH	New	CARDINAL HEALTH INC	$61,000	–	918	–	0.00%	–
ZTS	Sell	ZOETIS INCcl a	$36,000	-58.1%	246	-51.1%	0.00%	0.0%
UTHR	Buy	UNITED THERAPEUTICS CORP	$63,000	+40.0%	301	+56.0%	0.00%	0.0%
TSM	New	TAIWAN SEMICONDUCTOR MFG LTDsponsored ads	$53,000	–	770	–	0.00%	–
NVST	Buy	ENVISTA HOLDINGS CORP	$27,000	+42.1%	822	+69.8%	0.00%	–
UMC	New	UNITED MICROELECTRONICS CORPspon adr new	$15,000	–	2,698	–	0.00%	–
CTLT	New	CATALENT INC	$34,000	–	473	–	0.00%	–
SLN	Exit	SILENCE THERAPEUTICS PLCads	$0	–	-30,483	–	-0.01%	–
ARCT	Exit	ARCTURUS THERAPEUTICS HLDGS	$0	–	-39,550	–	-0.01%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-63,700	–	-0.02%	–
NVCR	Exit	NOVOCURE LTD	$0	–	-25,300	–	-0.02%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL IN	$0	–	-31,000	–	-0.03%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-42,300	–	-0.03%	–
PCRX	Exit	PACIRA BIOSCIENCES INC	$0	–	-51,936	–	-0.04%	–
ALKS	Exit	ALKERMES PLC	$0	–	-107,200	–	-0.04%	–
HCAT	Exit	HEALTH CATALYST INC	$0	–	-424,611	–	-0.09%	–
ONEM	Exit	1LIFE HEALTHCARE INC	$0	–	-836,190	–	-0.09%	–
RDUS	Exit	RADIUS HEALTH INC	$0	–	-8,796,538	–	-1.29%	–

Q2 2022

			Value		Shares		↓ Weighting
IONS	New	IONIS PHARMACEUTICALS INC	$361,927,000	–	9,776,528	–	5.12%	–
ARGX	New	ARGENX SEsponsored adr	$349,641,000	–	933,803	–	4.94%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$331,423,000	–	1,176,136	–	4.68%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$277,263,000	–	2,844,305	–	3.92%	–
MRNA	New	MODERNA INC	$225,324,000	–	1,577,351	–	3.18%	–
INCY	New	INCYTE CORP	$210,693,000	–	2,773,377	–	2.98%	–
ITCI	New	INTRA-CELLULAR THERAPIES INC	$191,183,000	–	3,349,379	–	2.70%	–
ISRG	New	INTUITIVE SURGICAL INC	$182,516,000	–	909,348	–	2.58%	–
ABT	New	ABBOTT LABS	$170,994,000	–	1,573,807	–	2.42%	–
UNH	New	UNITEDHEALTH GROUP INC	$155,138,000	–	302,044	–	2.19%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$154,336,000	–	1,058,186	–	2.18%	–
BSX	New	BOSTON SCIENTIFIC CORP	$143,496,000	–	3,850,171	–	2.03%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$143,203,000	–	917,907	–	2.02%	–
AXNX	New	AXONICS INC	$131,126,000	–	2,313,852	–	1.85%	–
ANTM	New	ELEVANCE HEALTH INC	$100,618,000	–	208,500	–	1.42%	–
SAGE	New	SAGE THERAPEUTICS INC	$96,034,000	–	2,973,178	–	1.36%	–
EW	New	EDWARDS LIFESCIENCES CORP	$96,101,000	–	1,010,627	–	1.36%	–
SYK	New	STRYKER CORPORATION	$95,016,000	–	477,634	–	1.34%	–
DHR	New	DANAHER CORPORATION	$92,290,000	–	364,036	–	1.30%	–
RDUS	New	RADIUS HEALTH INC	$91,220,000	–	8,796,538	–	1.29%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$90,072,000	–	4,062,792	–	1.27%	–
ARVN	New	ARVINAS INC	$89,411,000	–	2,124,276	–	1.26%	–
FATE	New	FATE THERAPEUTICS INC	$87,972,000	–	3,550,086	–	1.24%	–
SRPT	New	SAREPTA THERAPEUTICS INC	$85,414,000	–	1,139,455	–	1.21%	–
BDX	New	BECTON DICKINSON & CO	$84,555,000	–	342,982	–	1.20%	–
PODD	New	INSULET CORP	$84,198,000	–	386,335	–	1.19%	–
OPCH	New	OPTION CARE HEALTH INC	$80,237,000	–	2,887,259	–	1.13%	–
TNDM	New	TANDEM DIABETES CARE INC	$77,887,000	–	1,315,873	–	1.10%	–
INSP	New	INSPIRE MED SYS INC	$74,357,000	–	407,057	–	1.05%	–
MYOV	New	MYOVANT SCIENCES LTD	$73,581,000	–	5,919,639	–	1.04%	–
INSM	New	INSMED INC	$71,417,000	–	3,621,562	–	1.01%	–
SWAV	New	SHOCKWAVE MED INC	$70,867,000	–	370,699	–	1.00%	–
MOH	New	MOLINA HEALTHCARE INC	$69,431,000	–	248,313	–	0.98%	–
DXCM	New	DEXCOM INC	$69,202,000	–	928,508	–	0.98%	–
HUM	New	HUMANA INC	$68,015,000	–	145,309	–	0.96%	–
RLAY	New	RELAY THERAPEUTICS INC	$67,541,000	–	4,032,262	–	0.96%	–
RVMD	New	REVOLUTION MEDICINES INC	$65,940,000	–	3,383,262	–	0.93%	–
EVH	New	EVOLENT HEALTH INCcl a	$61,989,000	–	2,018,521	–	0.88%	–
AMED	New	AMEDISYS INC	$61,511,000	–	585,154	–	0.87%	–
MDT	New	MEDTRONIC PLC	$57,934,000	–	645,506	–	0.82%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$56,031,000	–	922,005	–	0.79%	–
EXEL	New	EXELIXIS INC	$55,767,000	–	2,678,500	–	0.79%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$54,554,000	–	1,206,422	–	0.77%	–
CDNA	New	CAREDX INC	$54,506,000	–	2,537,524	–	0.77%	–
CI	New	CIGNA CORP NEW	$51,032,000	–	193,657	–	0.72%	–
CRL	New	CHARLES RIV LABS INTL INC	$49,442,000	–	231,069	–	0.70%	–
HCA	New	HCA HEALTHCARE INC	$49,203,000	–	292,771	–	0.70%	–
OMCL	New	OMNICELL COM	$48,437,000	–	425,823	–	0.68%	–
CNC	New	CENTENE CORP DEL	$46,189,000	–	545,903	–	0.65%	–
BIO	New	BIO RAD LABS INCcl a	$45,125,000	–	91,161	–	0.64%	–
PFE	New	PFIZER INC	$43,815,000	–	835,684	–	0.62%	–
HALO	New	HALOZYME THERAPEUTICS INC	$42,737,000	–	971,300	–	0.60%	–
ABMD	New	ABIOMED INC	$41,955,000	–	169,509	–	0.59%	–
IDXX	New	IDEXX LABS INC	$40,605,000	–	115,773	–	0.57%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$39,017,000	–	71,818	–	0.55%	–
SILK	New	SILK RD MED INC	$38,111,000	–	1,047,286	–	0.54%	–
GMED	New	GLOBUS MED INCcl a	$36,866,000	–	656,681	–	0.52%	–
IQV	New	IQVIA HLDGS INC	$36,584,000	–	168,598	–	0.52%	–
LEGN	New	LEGEND BIOTECH CORPsponsored ads	$34,674,000	–	630,439	–	0.49%	–
OM	New	OUTSET MED INC	$34,575,000	–	2,326,718	–	0.49%	–
HRMY	New	HARMONY BIOSCIENCES HLDGS IN	$34,240,000	–	702,068	–	0.48%	–
VEEV	New	VEEVA SYS INC	$33,424,000	–	168,776	–	0.47%	–
ALGN	New	ALIGN TECHNOLOGY INC	$32,007,000	–	135,240	–	0.45%	–
AXSM	New	AXSOME THERAPEUTICS INC	$31,297,000	–	817,141	–	0.44%	–
EXAS	New	EXACT SCIENCES CORP	$29,859,000	–	758,023	–	0.42%	–
BAX	New	BAXTER INTL INC	$29,406,000	–	457,819	–	0.42%	–
ADPT	New	ADAPTIVE BIOTECHNOLOGIES COR	$28,631,000	–	3,539,055	–	0.40%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$27,955,000	–	266,087	–	0.40%	–
ESPR	New	ESPERION THERAPEUTICS INC NE	$26,936,000	–	4,235,264	–	0.38%	–
AUPH	New	AURINIA PHARMACEUTICALS INC	$26,848,000	–	2,671,413	–	0.38%	–
ACCD	New	ACCOLADE INC	$26,898,000	–	3,634,886	–	0.38%	–
HZNP	New	HORIZON THERAPEUTICS PUB L	$26,914,000	–	337,434	–	0.38%	–
PACB	New	PACIFIC BIOSCIENCES CALIF IN	$26,349,000	–	5,961,229	–	0.37%	–
ATRC	New	ATRICURE INC	$26,228,000	–	641,896	–	0.37%	–
COO	New	COOPER COS INC	$25,513,000	–	81,479	–	0.36%	–
KZR	New	KEZAR LIFE SCIENCES INC	$25,099,000	–	3,035,000	–	0.36%	–
CLDX	New	CELLDEX THERAPEUTICS	$24,938,000	–	925,000	–	0.35%	–
PEN	New	PENUMBRA INC	$23,981,000	–	192,588	–	0.34%	–
GBIO	New	GENERATION BIO CO	$23,795,000	–	3,627,280	–	0.34%	–
TFX	New	TELEFLEX INCORPORATED	$23,598,000	–	95,984	–	0.33%	–
BNTX	New	BIONTECH SEsponsored ads	$22,544,000	–	151,200	–	0.32%	–
BEAM	New	BEAM THERAPEUTICS INC	$22,166,000	–	572,621	–	0.31%	–
MGNX	New	MACROGENICS INC	$21,610,000	–	7,325,514	–	0.30%	–
HCM	New	HUTCHMED CHINA LTDsponsored ads	$21,359,000	–	1,756,307	–	0.30%	–
CVS	New	CVS HEALTH CORP	$21,233,000	–	229,153	–	0.30%	–
CSTL	New	CASTLE BIOSCIENCES INC	$20,656,000	–	941,059	–	0.29%	–
	New	PROCEPT BIOROBOTICS CORP	$19,463,000	–	595,380	–	0.28%	–
HOLX	New	HOLOGIC INC	$18,768,000	–	270,825	–	0.26%	–
TMDX	New	TRANSMEDICS GROUP INC	$18,237,000	–	579,887	–	0.26%	–
MRSN	New	MERSANA THERAPEUTICS INC	$17,996,000	–	3,895,200	–	0.25%	–
RMD	New	RESMED INC	$17,790,000	–	84,865	–	0.25%	–
PHR	New	PHREESIA INC	$17,011,000	–	680,153	–	0.24%	–
ILMN	New	ILLUMINA INC	$16,015,000	–	86,867	–	0.23%	–
EPIX	New	ESSA PHARMA INC	$15,781,000	–	5,009,714	–	0.22%	–
AVTR	New	AVANTOR INC	$15,644,000	–	503,007	–	0.22%	–
PRVA	New	PRIVIA HEALTH GROUP INC	$15,139,000	–	519,876	–	0.21%	–
WVE	New	WAVE LIFE SCIENCES LTD	$14,607,000	–	4,494,458	–	0.21%	–
TDOC	New	TELADOC HEALTH INC	$13,819,000	–	416,112	–	0.20%	–
AMGN	New	AMGEN INC	$12,398,000	–	50,959	–	0.18%	–
SRRK	New	SCHOLAR ROCK HLDG CORP	$11,815,000	–	2,152,025	–	0.17%	–
TXG	New	10X GENOMICS INC	$11,737,000	–	259,371	–	0.17%	–
BDTX	New	BLACK DIAMOND THERAPEUTICS I	$11,605,000	–	4,717,113	–	0.16%	–
NVRO	New	NEVRO CORP	$11,630,000	–	265,339	–	0.16%	–
REGN	New	REGENERON PHARMACEUTICALS	$10,479,000	–	17,727	–	0.15%	–
MTEM	New	MOLECULAR TEMPLATES INC	$10,281,000	–	11,278,003	–	0.14%	–
SGEN	New	SEAGEN INC	$8,737,000	–	49,376	–	0.12%	–
AMWL	New	AMERICAN WELL CORPcl a	$7,645,000	–	1,769,703	–	0.11%	–
ONEM	New	1LIFE HEALTHCARE INC	$6,556,000	–	836,190	–	0.09%	–
HCAT	New	HEALTH CATALYST INC	$6,153,000	–	424,611	–	0.09%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$6,112,000	–	73,753	–	0.09%	–
AZN	New	ASTRAZENECA PLCsponsored adr	$5,748,000	–	87,000	–	0.08%	–
JNJ	New	JOHNSON & JOHNSON	$5,133,000	–	28,914	–	0.07%	–
DOCS	New	DOXIMITY INCcl a	$4,747,000	–	136,322	–	0.07%	–
GILD	New	GILEAD SCIENCES INC	$4,662,000	–	75,426	–	0.07%	–
BIIB	New	BIOGEN INC	$4,456,000	–	21,850	–	0.06%	–
OLK	New	OLINK HLDG ABsponsored ads	$3,576,000	–	235,273	–	0.05%	–
FIXX	New	HOMOLOGY MEDICINES INC	$3,196,000	–	1,622,522	–	0.04%	–
ALKS	New	ALKERMES PLC	$3,193,000	–	107,200	–	0.04%	–
PCRX	New	PACIRA BIOSCIENCES INC	$3,028,000	–	51,936	–	0.04%	–
GH	New	GUARDANT HEALTH INC	$2,847,000	–	70,580	–	0.04%	–
CYTK	New	CYTOKINETICS INC	$2,609,000	–	66,400	–	0.04%	–
	New	SIGHT SCIENCES INC	$2,649,000	–	294,606	–	0.04%	–
LUNG	New	PULMONX CORP	$2,552,000	–	173,336	–	0.04%	–
NPCE	New	NEUROPACE INC	$2,514,000	–	507,930	–	0.04%	–
SUPN	New	SUPERNUS PHARMACEUTICALS INC	$2,383,000	–	82,400	–	0.03%	–
RCUS	New	ARCUS BIOSCIENCES INC	$2,283,000	–	90,100	–	0.03%	–
SNY	New	SANOFIsponsored adr	$2,116,000	–	42,300	–	0.03%	–
KOS	New	KOSMOS ENERGY LTD	$1,970,000	–	318,300	–	0.03%	–
BLI	New	BERKELEY LTS INC	$1,914,000	–	385,014	–	0.03%	–
BMY	New	BRISTOL-MYERS SQUIBB CO	$1,918,000	–	24,907	–	0.03%	–
ABC	New	AMERISOURCEBERGEN CORP	$1,839,000	–	13,000	–	0.03%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL IN	$1,849,000	–	31,000	–	0.03%	–
NVCR	New	NOVOCURE LTD	$1,758,000	–	25,300	–	0.02%	–
BCYC	New	BICYCLE THERAPEUTICS PLCsponsored ads	$1,416,000	–	84,400	–	0.02%	–
KURA	New	KURA ONCOLOGY INC	$1,168,000	–	63,700	–	0.02%	–
SEER	New	SEER INC	$1,218,000	–	136,133	–	0.02%	–
LH	New	LABORATORY CORP AMER HLDGS	$996,000	–	4,250	–	0.01%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$817,000	–	15,794	–	0.01%	–
MCK	New	MCKESSON CORP	$828,000	–	2,537	–	0.01%	–
KRYS	New	KRYSTAL BIOTECH INC	$880,000	–	13,400	–	0.01%	–
INBX	New	INHIBRX INC	$869,000	–	76,600	–	0.01%	–
XNCR	New	XENCOR INC	$725,000	–	26,500	–	0.01%	–
RDY	New	DR REDDYS LABS LTDadr	$687,000	–	12,400	–	0.01%	–
GOOG	New	ALPHABET INCcap stk cl c	$656,000	–	300	–	0.01%	–
ARCT	New	ARCTURUS THERAPEUTICS HLDGS	$623,000	–	39,550	–	0.01%	–
RLMD	New	RELMADA THERAPEUTICS INC	$665,000	–	35,000	–	0.01%	–
VRDN	New	VIRIDIAN THERAPEUTICS INC	$567,000	–	49,000	–	0.01%	–
GDX	New	VANECK ETF TRUSTgold miners etf	$367,000	–	13,400	–	0.01%	–
SLN	New	SILENCE THERAPEUTICS PLCads	$361,000	–	30,483	–	0.01%	–
	New	CARIBOU BIOSCIENCES INC	$382,000	–	70,300	–	0.01%	–
EL	New	LAUDER ESTEE COS INCcl a	$343,000	–	1,348	–	0.01%	–
OPT	New	OPTHEA LTDsponsored ads	$296,000	–	47,000	–	0.00%	–
LLY	New	LILLY ELI & CO	$314,000	–	969	–	0.00%	–
MCHI	New	ISHARES TRmsci china etf	$229,000	–	4,100	–	0.00%	–
SWKS	New	SKYWORKS SOLUTIONS INC	$195,000	–	2,100	–	0.00%	–
MELI	New	MERCADOLIBRE INC	$108,000	–	170	–	0.00%	–
GDXJ	New	VANECK ETF TRUSTjunior gold mine	$160,000	–	5,000	–	0.00%	–
MKTX	New	MARKETAXESS HLDGS INC	$169,000	–	662	–	0.00%	–
DLB	New	DOLBY LABORATORIES INC	$114,000	–	1,600	–	0.00%	–
JMIA	New	JUMIA TECHNOLOGIES AGsponsored ads	$109,000	–	18,000	–	0.00%	–
ABBV	New	ABBVIE INC	$124,000	–	808	–	0.00%	–
NKTR	New	NEKTAR THERAPEUTICS	$109,000	–	28,800	–	0.00%	–
ZTS	New	ZOETIS INCcl a	$86,000	–	503	–	0.00%	–
MRK	New	MERCK & CO. INC	$88,000	–	964	–	0.00%	–
UTHR	New	UNITED THERAPEUTICS CORP DEL	$45,000	–	193	–	0.00%	–
IPGP	New	IPG PHOTONICS CORP	$99,000	–	1,050	–	0.00%	–
AVLR	New	AVALARA INC	$92,000	–	1,300	–	0.00%	–
EQIX	New	EQUINIX INC	$26,000	–	40	–	0.00%	–
NVST	New	ENVISTA HOLDINGS CORPORATION	$19,000	–	484	–	0.00%	–
ASR	New	GRUPO AEROPORTUARIO DEL SUREspon adr ser b	$27,000	–	135	–	0.00%	–
EVTC	New	EVERTEC INC	$27,000	–	739	–	0.00%	–
INFY	New	INFOSYS LTDsponsored adr	$21,000	–	1,130	–	0.00%	–

Q4 2021

			Value		Shares		↓ Weighting
CVAC	Exit	CUREVAC N Vcall	$0	–	-120	–	0.00%	–
STNE	Exit	STONECO LTD	$0	–	-4,300	–	-0.00%	–
OLED	Exit	UNIVERSAL DISPLAY CORP	$0	–	-1,365	–	-0.00%	–
IPGP	Exit	IPG PHOTONICS CORP	$0	–	-1,350	–	-0.00%	–
SPOT	Exit	SPOTIFY TECHNOLOGY SA	$0	–	-1,100	–	-0.00%	–
MKC	Exit	MCCORMICK & CO INC	$0	–	-4,000	–	-0.00%	–
ST	Exit	SENSATA TECHNOLOGIES HLDNG PL	$0	–	-5,900	–	-0.00%	–
CYBR	Exit	CYBERARK SOFTWARE LTD	$0	–	-2,100	–	-0.00%	–
MELI	Exit	MERCADOLIBRE INC	$0	–	-170	–	-0.00%	–
MKTX	Exit	MARKETAXESS HLDGS INC	$0	–	-662	–	-0.00%	–
TCOM	Exit	TRIP COM GROUP LTDads	$0	–	-10,000	–	-0.00%	–
STZ	Exit	CONSTELLATION BRANDS INCcl a	$0	–	-1,459	–	-0.00%	–
CLX	Exit	CLOROX CO DEL	$0	–	-2,000	–	-0.00%	–
CSGP	Exit	COSTAR GROUP INC	$0	–	-3,500	–	-0.00%	–
GGG	Exit	GRACO INC	$0	–	-4,500	–	-0.00%	–
AZPN	Exit	ASPEN TECHNOLOGY INC	$0	–	-2,400	–	-0.00%	–
DLB	Exit	DOLBY LABORATORIES INC	$0	–	-3,600	–	-0.00%	–
JD	Exit	JD.COM INCspon adr cl a	$0	–	-3,600	–	-0.00%	–
ANSS	Exit	ANSYS INC	$0	–	-900	–	-0.00%	–
BFB	Exit	BROWN FORMAN CORPcl b	$0	–	-4,600	–	-0.00%	–
JMIA	Exit	JUMIA TECHNOLOGIES AGsponsored ads	$0	–	-18,000	–	-0.00%	–
EA	Exit	ELECTRONIC ARTS INC	$0	–	-2,270	–	-0.00%	–
ICE	Exit	INTERCONTINENTAL EXCHANGE IN	$0	–	-3,000	–	-0.00%	–
WSO	Exit	WATSCO INC	$0	–	-1,300	–	-0.00%	–
ENTG	Exit	ENTEGRIS INC	$0	–	-3,000	–	-0.00%	–
TRMB	Exit	TRIMBLE INC	$0	–	-4,800	–	-0.00%	–
LYV	Exit	LIVE NATION ENTERTAINMENT IN	$0	–	-4,700	–	-0.00%	–
NYT	Exit	NEW YORK TIMES COcl a	$0	–	-7,500	–	-0.00%	–
POOL	Exit	POOL CORP	$0	–	-900	–	-0.00%	–
TRU	Exit	TRANSUNION	$0	–	-3,696	–	-0.00%	–
BKNG	Exit	BOOKING HOLDINGS INC	$0	–	-160	–	-0.00%	–
SCI	Exit	SERVICE CORP INTL	$0	–	-6,500	–	-0.00%	–
OPT	Exit	OPTHEA LTDsponsored ads	$0	–	-49,000	–	-0.00%	–
MKL	Exit	MARKEL CORP	$0	–	-300	–	-0.00%	–
TW	Exit	TRADEWEB MKTS INCcl a	$0	–	-5,200	–	-0.00%	–
FDS	Exit	FACTSET RESH SYS INC	$0	–	-1,050	–	-0.00%	–
VRSK	Exit	VERISK ANALYTICS INC	$0	–	-1,739	–	-0.00%	–
MTCH	Exit	MATCH GROUP INC NEW	$0	–	-2,378	–	-0.00%	–
SBUX	Exit	STARBUCKS CORP	$0	–	-3,234	–	-0.00%	–
A	Exit	AGILENT TECHNOLOGIES INC	$0	–	-2,700	–	-0.00%	–
TYL	Exit	TYLER TECHNOLOGIES INC	$0	–	-800	–	-0.00%	–
KMX	Exit	CARMAX INC	$0	–	-2,850	–	-0.00%	–
MTD	Exit	METTLER TOLEDO INTERNATIONAL	$0	–	-270	–	-0.00%	–
AVLR	Exit	AVALARA INC	$0	–	-2,300	–	-0.00%	–
VRSN	Exit	VERISIGN INC	$0	–	-1,700	–	-0.00%	–
WAB	Exit	WABTEC	$0	–	-4,200	–	-0.00%	–
EL	Exit	LAUDER ESTEE COS INCcl a	$0	–	-1,348	–	-0.00%	–
AXP	Exit	AMERICAN EXPRESS CO	$0	–	-2,600	–	-0.00%	–
FAST	Exit	FASTENAL CO	$0	–	-7,000	–	-0.00%	–
SWKS	Exit	SKYWORKS SOLUTIONS INC	$0	–	-2,100	–	-0.00%	–
PKI	Exit	PERKINELMER INC	$0	–	-2,200	–	-0.00%	–
ULTA	Exit	ULTA BEAUTY INC	$0	–	-1,100	–	-0.00%	–
MCK	Exit	MCKESSON CORP	$0	–	-2,430	–	-0.01%	–
INTU	Exit	INTUIT	$0	–	-900	–	-0.01%	–
MSCI	Exit	MSCI INC	$0	–	-816	–	-0.01%	–
SPGI	Exit	S&P GLOBAL INC	$0	–	-1,200	–	-0.01%	–
MCO	Exit	MOODYS CORP	$0	–	-1,250	–	-0.01%	–
DPZ	Exit	DOMINOS PIZZA INC	$0	–	-1,000	–	-0.01%	–
IT	Exit	GARTNER INC	$0	–	-2,100	–	-0.01%	–
RDY	Exit	DR REDDYS LABS LTDadr	$0	–	-8,500	–	-0.01%	–
FTNT	Exit	FORTINET INC	$0	–	-2,200	–	-0.01%	–
ACIU	Exit	AC IMMUNE SA	$0	–	-139,000	–	-0.01%	–
KOS	Exit	KOSMOS ENERGY LTD	$0	–	-292,000	–	-0.01%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-57,500	–	-0.01%	–
CLLS	Exit	CELLECTIS S Aspon ads	$0	–	-82,500	–	-0.01%	–
ZTS	Exit	ZOETIS INCcl a	$0	–	-7,100	–	-0.01%	–
APLS	Exit	APELLIS PHARMACEUTICALS INC	$0	–	-48,000	–	-0.02%	–
XNCR	Exit	XENCOR INC	$0	–	-52,100	–	-0.02%	–
ARCT	Exit	ARCTURUS THERAPEUTICS HLDGS	$0	–	-34,500	–	-0.02%	–
DGX	Exit	QUEST DIAGNOSTICS INC	$0	–	-13,000	–	-0.02%	–
CDNA	Exit	CAREDX INC	$0	–	-30,943	–	-0.02%	–
CVAC	Exit	CUREVAC N V	$0	–	-35,200	–	-0.02%	–
ALLK	Exit	ALLAKOS INC	$0	–	-18,500	–	-0.02%	–
CCCC	Exit	C4 THERAPEUTICS INC	$0	–	-47,200	–	-0.02%	–
KYMR	Exit	KYMERA THERAPEUTICS INC	$0	–	-35,500	–	-0.02%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-16,594	–	-0.02%	–
BHVN	Exit	BIOHAVEN PHARMACTL HLDG CO L	$0	–	-17,500	–	-0.02%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL IN	$0	–	-27,900	–	-0.03%	–
BCYC	Exit	BICYCLE THERAPEUTICS PLCsponsored ads	$0	–	-65,700	–	-0.03%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-67,000	–	-0.03%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-18,900	–	-0.03%	–
NVAX	Exit	NOVAVAX INC	$0	–	-16,000	–	-0.03%	–
RCUS	Exit	ARCUS BIOSCIENCES INC	$0	–	-94,700	–	-0.03%	–
BNTX	Exit	BIONTECH SEsponsored ads	$0	–	-12,700	–	-0.04%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-51,700	–	-0.04%	–
PFE	Exit	PFIZER INC	$0	–	-99,600	–	-0.04%	–
SEER	Exit	SEER INC	$0	–	-136,133	–	-0.05%	–
CTLT	Exit	CATALENT INC	$0	–	-36,000	–	-0.05%	–
OLK	Exit	OLINK HLDG ABsponsored ads	$0	–	-197,527	–	-0.05%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-30,500	–	-0.05%	–
HRMY	Exit	HARMONY BIOSCIENCES HLDGS IN	$0	–	-129,289	–	-0.05%	–
SYNH	Exit	SYNEOS HEALTH INCcl a	$0	–	-57,000	–	-0.05%	–
	Exit	PROCEPT BIOROBOTICS CORP	$0	–	-150,000	–	-0.06%	–
LUNG	Exit	PULMONX CORP	$0	–	-176,510	–	-0.06%	–
	Exit	SIGHT SCIENCES INC	$0	–	-300,000	–	-0.07%	–
GKOS	Exit	GLAUKOS CORP	$0	–	-143,870	–	-0.07%	–
AMGN	Exit	AMGEN INC	$0	–	-33,950	–	-0.07%	–
BLI	Exit	BERKELEY LTS INC	$0	–	-385,014	–	-0.08%	–
NPCE	Exit	NEUROPACE INC	$0	–	-507,930	–	-0.08%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-23,000	–	-0.08%	–
BNR	Exit	BURNING ROCK BIOTECH LTDsponsored ads	$0	–	-489,890	–	-0.09%	–
SGEN	Exit	SEAGEN INC	$0	–	-53,400	–	-0.09%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-159,129	–	-0.09%	–
GTH	Exit	GENETRON HLDGS LTDads	$0	–	-723,137	–	-0.10%	–
INGN	Exit	INOGEN INC	$0	–	-242,174	–	-0.11%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-157,000	–	-0.11%	–
OSCR	Exit	OSCAR HEALTH INCcl a	$0	–	-679,952	–	-0.12%	–
IMAB	Exit	I MABsponsored ads	$0	–	-162,957	–	-0.12%	–
BHG	Exit	BRIGHT HEALTH GROUP INC	$0	–	-1,500,000	–	-0.12%	–
LH	Exit	LABORATORY CORP AMER HLDGS	$0	–	-44,100	–	-0.13%	–
PRVA	Exit	PRIVIA HEALTH GROUP INC	$0	–	-525,000	–	-0.13%	–
WVE	Exit	WAVE LIFE SCIENCES LTD	$0	–	-2,602,858	–	-0.13%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-125,000	–	-0.13%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-158,548	–	-0.14%	–
FIXX	Exit	HOMOLOGY MEDICINES INC	$0	–	-1,737,122	–	-0.14%	–
LEGN	Exit	LEGEND BIOTECH CORPsponsored ads	$0	–	-286,556	–	-0.15%	–
ONEM	Exit	1LIFE HEALTHCARE INC	$0	–	-836,190	–	-0.17%	–
TMDX	Exit	TRANSMEDICS GROUP INC	$0	–	-581,029	–	-0.20%	–
AMWL	Exit	AMERICAN WELL CORPcl a	$0	–	-2,127,838	–	-0.20%	–
AVTR	Exit	AVANTOR INC	$0	–	-512,216	–	-0.21%	–
OM	Exit	OUTSET MED INC	$0	–	-457,060	–	-0.23%	–
RMD	Exit	RESMED INC	$0	–	-88,145	–	-0.24%	–
AXSM	Exit	AXSOME THERAPEUTICS INC	$0	–	-752,945	–	-0.25%	–
NVRO	Exit	NEVRO CORP	$0	–	-214,956	–	-0.25%	–
CRL	Exit	CHARLES RIV LABS INTL INC	$0	–	-63,329	–	-0.26%	–
NEO	Exit	NEOGENOMICS INC	$0	–	-561,683	–	-0.28%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-215,906	–	-0.28%	–
ILMN	Exit	ILLUMINA INC	$0	–	-70,130	–	-0.29%	–
ATRC	Exit	ATRICURE INC	$0	–	-418,016	–	-0.30%	–
BDTX	Exit	BLACK DIAMOND THERAPEUTICS I	$0	–	-3,463,000	–	-0.30%	–
QTRX	Exit	QUANTERIX CORP	$0	–	-593,819	–	-0.30%	–
ABBV	Exit	ABBVIE INC	$0	–	-282,900	–	-0.31%	–
COO	Exit	COOPER COS INC	$0	–	-74,266	–	-0.31%	–
TXG	Exit	10X GENOMICS INC	$0	–	-232,672	–	-0.34%	–
BIO	Exit	BIO RAD LABS INCcl a	$0	–	-46,015	–	-0.35%	–
MASI	Exit	MASIMO CORP	$0	–	-127,713	–	-0.35%	–
HCAT	Exit	HEALTH CATALYST INC	$0	–	-727,233	–	-0.37%	–
HCM	Exit	HUTCHMED CHINA LTDsponsored ads	$0	–	-1,006,147	–	-0.37%	–
TFX	Exit	TELEFLEX INCORPORATED	$0	–	-97,818	–	-0.37%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-921,500	–	-0.38%	–
PHR	Exit	PHREESIA INC	$0	–	-622,542	–	-0.39%	–
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-4,533,148	–	-0.40%	–
MRSN	Exit	MERSANA THERAPEUTICS INC	$0	–	-4,261,000	–	-0.41%	–
EPIX	Exit	ESSA PHARMA INC	$0	–	-5,034,814	–	-0.41%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-280,082	–	-0.42%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-429,273	–	-0.42%	–
PACB	Exit	PACIFIC BIOSIENCES CALIF IN	$0	–	-1,643,159	–	-0.43%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-339,125	–	-0.43%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-339,894	–	-0.43%	–
SILK	Exit	SILK RD MED INC	$0	–	-781,660	–	-0.44%	–
CI	Exit	CIGNA CORP NEW	$0	–	-217,812	–	-0.44%	–
AMED	Exit	AMEDISYS INC	$0	–	-302,798	–	-0.46%	–
ADPT	Exit	ADAPTIVE BIOTECHNOLOGIES COR	$0	–	-1,336,023	–	-0.46%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB L	$0	–	-416,200	–	-0.46%	–
IQV	Exit	IQVIA HLDGS INC	$0	–	-190,620	–	-0.46%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-168,255	–	-0.46%	–
ABMD	Exit	ABIOMED INC	$0	–	-151,178	–	-0.50%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-86,879	–	-0.50%	–
VEEV	Exit	VEEVA SYS INC	$0	–	-174,551	–	-0.51%	–
SRPT	Exit	SAREPTA THERAPEUTICS INC	$0	–	-569,168	–	-0.53%	–
VCRA	Exit	VOCERA COMMUNICATONS INC	$0	–	-1,154,041	–	-0.54%	–
BEAM	Exit	BEAM THERAPEUTICS INC	$0	–	-612,821	–	-0.54%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NE	$0	–	-4,519,164	–	-0.55%	–
PEN	Exit	PENUMBRA INC	$0	–	-205,692	–	-0.56%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-729,420	–	-0.57%	–
OMCL	Exit	OMNICELL INC	$0	–	-393,583	–	-0.59%	–
EXEL	Exit	EXELIXIS INC	$0	–	-2,859,000	–	-0.61%	–
GBIO	Exit	GENERATION BIO CO	$0	–	-2,472,180	–	-0.63%	–
OPCH	Exit	OPTION CARE HEALTH INC	$0	–	-2,595,814	–	-0.64%	–
HRC	Exit	HILL-ROM HLDGS INC	$0	–	-420,716	–	-0.64%	–
HOLX	Exit	HOLOGIC INC	$0	–	-870,662	–	-0.65%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-106,410	–	-0.65%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-1,154,545	–	-0.73%	–
MTEM	Exit	MOLECULAR TEMPLATES INC	$0	–	-10,878,003	–	-0.74%	–
IDXX	Exit	IDEXX LABS INC	$0	–	-118,120	–	-0.74%	–
BAX	Exit	BAXTER INTL INC	$0	–	-923,223	–	-0.75%	–
SRRK	Exit	SCHOLAR ROCK HLDG CORP	$0	–	-2,294,425	–	-0.77%	–
BMY	Exit	BRISTOL-MYERS SQUIBB CO	$0	–	-1,302,934	–	-0.78%	–
ACCD	Exit	ACCOLADE INC	$0	–	-1,860,203	–	-0.80%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-4,594,656	–	-0.84%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-341,473	–	-0.84%	–
INSM	Exit	INSMED INC	$0	–	-3,385,645	–	-0.95%	–
EVH	Exit	EVOLENT HEALTH INCcl a	$0	–	-3,032,678	–	-0.95%	–
RVMD	Exit	REVOLUTION MEDICINES INC	$0	–	-3,458,805	–	-0.97%	–
SWAV	Exit	SHOCKWAVE MED INC	$0	–	-464,247	–	-0.97%	–
RDUS	Exit	RADIUS HEALTH INC	$0	–	-7,768,714	–	-0.98%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-421,058	–	-1.00%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-869,951	–	-1.00%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-769,238	–	-1.02%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-157,031	–	-1.06%	–
AXNX	Exit	AXONICS INC	$0	–	-1,608,794	–	-1.06%	–
PODD	Exit	INSULET CORP	$0	–	-382,994	–	-1.10%	–
CRSP	Exit	CRISPR THERAPEUTICS AGnamen akt	$0	–	-974,684	–	-1.11%	–
SYK	Exit	STRYKER CORPORATION	$0	–	-422,332	–	-1.13%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-455,572	–	-1.14%	–
RLAY	Exit	RELAY THERAPEUTICS INC	$0	–	-3,755,962	–	-1.20%	–
HUM	Exit	HUMANA INC	$0	–	-312,762	–	-1.24%	–
TNDM	Exit	TANDEM DIABETES CARE INC	$0	–	-1,034,519	–	-1.25%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-2,967,127	–	-1.31%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-5,769,039	–	-1.31%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-337,982	–	-1.34%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-456,679	–	-1.41%	–
ITCI	Exit	INTRA-CELLULAR THERAPIES INC	$0	–	-3,773,919	–	-1.43%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-3,209,004	–	-1.44%	–
DXCM	Exit	DEXCOM INC	$0	–	-263,839	–	-1.46%	–
BIIB	Exit	BIOGEN INC	$0	–	-527,000	–	-1.51%	–
ABT	Exit	ABBOTT LABS	$0	–	-1,387,499	–	-1.66%	–
ANTM	Exit	ANTHEM INC	$0	–	-475,210	–	-1.80%	–
MGNX	Exit	MACROGENICS INC	$0	–	-8,544,597	–	-1.82%	–
ARVN	Exit	ARVINAS INC	$0	–	-2,241,403	–	-1.87%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-3,238,036	–	-1.95%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-4,341,992	–	-2.03%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-203,595	–	-2.05%	–
INCY	Exit	INCYTE CORP	$0	–	-2,957,000	–	-2.06%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-1,408,418	–	-2.70%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-3,004,051	–	-2.92%	–
ARGX	Exit	ARGENX SEsponsored adr	$0	–	-983,938	–	-3.02%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-9,347,926	–	-3.18%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-1,761,616	–	-3.24%	–
MRNA	Exit	MODERNA INC	$0	–	-1,727,349	–	-6.75%	–

Q3 2021

			Value		Shares		↓ Weighting
MRNA	Sell	MODERNA INC	$664,787,000	+11.3%	1,727,349	-32.1%	6.75%	+15.7%
VRTX	Buy	VERTEX PHARMACEUTICALS INC	$319,540,000	-8.6%	1,761,616	+1.6%	3.24%	-5.0%
IONS	Sell	IONIS PHARMACEUTICALS INC	$313,529,000	-20.8%	9,347,926	-5.9%	3.18%	-17.7%
ARGX	Buy	ARGENX SEsponsored adr	$297,149,000	+1.3%	983,938	+1.0%	3.02%	+5.3%
NBIX	Sell	NEUROCRINE BIOSCIENCES INC	$288,119,000	-1.9%	3,004,051	-0.5%	2.92%	+2.0%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$265,924,000	+1.3%	1,408,418	-9.1%	2.70%	+5.3%
INCY	Sell	INCYTE CORP	$203,383,000	-18.6%	2,957,000	-0.5%	2.06%	-15.4%
ISRG	Buy	INTUITIVE SURGICAL INC	$202,404,000	+8.9%	203,595	+0.7%	2.05%	+13.2%
AGIO	Sell	AGIOS PHARMACEUTICALS INC	$200,383,000	-16.5%	4,341,992	-0.3%	2.03%	-13.2%
FATE	Buy	FATE THERAPEUTICS INC	$191,918,000	-15.4%	3,238,036	+23.9%	1.95%	-12.0%
ARVN	Buy	ARVINAS INC	$184,199,000	+6.9%	2,241,403	+0.2%	1.87%	+11.1%
MGNX	Buy	MACROGENICS INC	$178,924,000	-9.7%	8,544,597	+15.8%	1.82%	-6.1%
ANTM	Buy	ANTHEM INC	$177,158,000	-0.4%	475,210	+2.0%	1.80%	+3.5%
ABT	Buy	ABBOTT LABS	$163,905,000	+2.6%	1,387,499	+0.7%	1.66%	+6.7%
BIIB	Sell	BIOGEN INC	$149,136,000	-18.4%	527,000	-0.2%	1.51%	-15.2%
DXCM	Buy	DEXCOM INC	$144,283,000	+38.0%	263,839	+7.8%	1.46%	+43.5%
SAGE	Buy	SAGE THERAPEUTICS INC	$142,191,000	+5.9%	3,209,004	+35.7%	1.44%	+10.1%
ITCI	Buy	INTRA-CELLULAR THERAPIES INC	$140,691,000	-4.5%	3,773,919	+4.5%	1.43%	-0.7%
DHR	Sell	DANAHER CORPORATION	$139,031,000	+7.3%	456,679	-5.4%	1.41%	+11.5%
UNH	Sell	UNITEDHEALTH GROUP INC	$132,063,000	-3.9%	337,982	-1.5%	1.34%	-0.1%
MYOV	Buy	MYOVANT SCIENCES LTD	$129,458,000	+7.9%	5,769,039	+9.5%	1.31%	+12.2%
BSX	Buy	BOSTON SCIENTIFIC CORP	$128,744,000	+29.4%	2,967,127	+27.5%	1.31%	+34.6%
TNDM	Buy	TANDEM DIABETES CARE INC	$123,500,000	+24.3%	1,034,519	+1.4%	1.25%	+29.2%
HUM	Buy	HUMANA INC	$121,712,000	-2.8%	312,762	+10.6%	1.24%	+1.1%
RLAY	Buy	RELAY THERAPEUTICS INC	$118,426,000	+22.6%	3,755,962	+42.2%	1.20%	+27.5%
BDX	Sell	BECTON DICKINSON & CO	$111,989,000	-0.1%	455,572	-1.2%	1.14%	+3.8%
SYK	Buy	STRYKER CORPORATION	$111,377,000	+24.5%	422,332	+22.6%	1.13%	+29.4%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$109,096,000	-30.3%	974,684	+0.8%	1.11%	-27.6%
PODD	Buy	INSULET CORP	$108,858,000	+23.1%	382,994	+18.9%	1.10%	+28.0%
AXNX	Sell	AXONICS INC	$104,716,000	-4.6%	1,608,794	-7.0%	1.06%	-0.7%
ALGN	Buy	ALIGN TECHNOLOGY INC	$104,493,000	+9.1%	157,031	+0.2%	1.06%	+13.4%
JAZZ	Buy	JAZZ PHARMACEUTICALS PLC	$100,162,000	+3.5%	769,238	+41.2%	1.02%	+7.5%
EW	Sell	EDWARDS LIFESCIENCES CORP	$98,487,000	+6.8%	869,951	-2.3%	1.00%	+11.0%
INSP	Buy	INSPIRE MED SYS INC	$98,056,000	+35.9%	421,058	+12.8%	1.00%	+41.3%
RDUS	Buy	RADIUS HEALTH INC	$96,410,000	-29.8%	7,768,714	+3.2%	0.98%	-27.1%
SWAV	Sell	SHOCKWAVE MED INC	$95,579,000	-2.5%	464,247	-10.2%	0.97%	+1.4%
RVMD	Buy	REVOLUTION MEDICINES INC	$95,152,000	+61.6%	3,458,805	+86.5%	0.97%	+68.0%
EVH	Sell	EVOLENT HEALTH INCcl a	$94,013,000	+22.3%	3,032,678	-16.6%	0.95%	+27.2%
INSM	Buy	INSMED INC	$93,241,000	+5.0%	3,385,645	+8.5%	0.95%	+9.1%
HCA	Buy	HCA HEALTHCARE INC	$82,882,000	+19.9%	341,473	+2.2%	0.84%	+24.6%
NKTR	Buy	NEKTAR THERAPEUTICS	$82,519,000	+17.2%	4,594,656	+12.0%	0.84%	+21.8%
ACCD	Buy	ACCOLADE INC	$78,445,000	-16.3%	1,860,203	+7.9%	0.80%	-12.9%
BMY	Sell	BRISTOL-MYERS SQUIBB CO	$77,095,000	-21.2%	1,302,934	-11.0%	0.78%	-18.1%
SRRK	Sell	SCHOLAR ROCK HLDG CORP	$75,762,000	+14.1%	2,294,425	-0.1%	0.77%	+18.7%
BAX	Buy	BAXTER INTL INC	$74,255,000	+2.4%	923,223	+2.5%	0.75%	+6.5%
MTEM	Buy	MOLECULAR TEMPLATES INC	$72,991,000	-3.1%	10,878,003	+13.0%	0.74%	+0.8%
CNC	Sell	CENTENE CORP DEL	$71,940,000	-28.8%	1,154,545	-16.7%	0.73%	-26.0%
REGN	Buy	REGENERON PHARMACEUTICALS	$64,397,000	+9.1%	106,410	+0.7%	0.65%	+13.5%
HOLX	Sell	HOLOGIC INC	$64,264,000	+5.4%	870,662	-4.7%	0.65%	+9.6%
HRC	Sell	HILL-ROM HLDGS INC	$63,107,000	-17.6%	420,716	-37.6%	0.64%	-14.3%
OPCH	Buy	OPTION CARE HEALTH INC	$62,974,000	+60.8%	2,595,814	+45.0%	0.64%	+67.3%
GBIO	Sell	GENERATION BIO CO	$61,977,000	-7.0%	2,472,180	-0.2%	0.63%	-3.4%
EXEL	Sell	EXELIXIS INC	$60,439,000	+13.1%	2,859,000	-2.5%	0.61%	+17.7%
PEN	Buy	PENUMBRA INC	$54,817,000	+9.8%	205,692	+12.9%	0.56%	+14.2%
VCRA	Buy	VOCERA COMMUNICATONS INC	$52,809,000	+103.0%	1,154,041	+76.8%	0.54%	+111.0%
SRPT	New	SAREPTA THERAPEUTICS INC	$52,637,000	–	569,168	–	0.53%	–
VEEV	Buy	VEEVA SYS INC	$50,300,000	-6.3%	174,551	+1.1%	0.51%	-2.7%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$49,637,000	+134.4%	86,879	+107.0%	0.50%	+143.5%
MOH	Sell	MOLINA HEALTHCARE INC	$45,649,000	-9.2%	168,255	-15.3%	0.46%	-5.7%
HZNP	Sell	HORIZON THERAPEUTICS PUB L	$45,591,000	+16.6%	416,200	-0.4%	0.46%	+21.2%
IQV	Buy	IQVIA HLDGS INC	$45,661,000	+6.2%	190,620	+7.5%	0.46%	+10.2%
ADPT	Buy	ADAPTIVE BIOTECHNOLOGIES COR	$45,411,000	+15.5%	1,336,023	+38.8%	0.46%	+20.1%
AMED	Buy	AMEDISYS INC	$45,148,000	+204.7%	302,798	+400.6%	0.46%	+215.9%
CI	Sell	CIGNA CORP NEW	$43,597,000	-28.4%	217,812	-15.2%	0.44%	-25.6%
SILK	Sell	SILK RD MED INC	$43,015,000	-30.5%	781,660	-39.6%	0.44%	-27.6%
GH	Sell	GUARDANT HEALTH INC	$42,490,000	-9.9%	339,894	-10.5%	0.43%	-6.3%
MDT	Sell	MEDTRONIC PLC	$42,509,000	-4.8%	339,125	-5.7%	0.43%	-1.1%
EXAS	Buy	EXACT SCIENCES CORP	$40,974,000	+19.6%	429,273	+55.7%	0.42%	+24.2%
EPIX	Buy	ESSA PHARMA INC	$40,279,000	-42.7%	5,034,814	+104.7%	0.41%	-40.4%
MRSN	Buy	MERSANA THERAPEUTICS INC	$40,181,000	+0.6%	4,261,000	+44.9%	0.41%	+4.6%
HALO	Sell	HALOZYME THERAPEUTICS INC	$37,487,000	-62.9%	921,500	-58.6%	0.38%	-61.5%
TFX	Sell	TELEFLEX INCORPORATED	$36,833,000	-8.5%	97,818	-2.3%	0.37%	-4.8%
HCM	Buy	HUTCHMED CHINA LTDsponsored ads	$36,835,000	+8.5%	1,006,147	+16.3%	0.37%	+13.0%
HCAT	Sell	HEALTH CATALYST INC	$36,369,000	-13.1%	727,233	-3.5%	0.37%	-9.6%
BIO	Sell	BIO RAD LABS INCcl a	$34,325,000	-39.0%	46,015	-47.3%	0.35%	-36.6%
ABBV	Sell	ABBVIE INC	$30,516,000	-16.4%	282,900	-12.7%	0.31%	-12.9%
QTRX	Sell	QUANTERIX CORP	$29,566,000	-21.0%	593,819	-6.9%	0.30%	-17.8%
ATRC	Buy	ATRICURE INC	$29,073,000	-2.1%	418,016	+11.6%	0.30%	+1.7%
ILMN	Sell	ILLUMINA INC	$28,445,000	-20.2%	70,130	-6.9%	0.29%	-17.0%
TDOC	Sell	TELADOC HEALTH INC	$27,379,000	-36.2%	215,906	-16.3%	0.28%	-33.7%
NEO	Sell	NEOGENOMICS INC	$27,096,000	-26.7%	561,683	-31.4%	0.28%	-23.8%
CRL	Sell	CHARLES RIV LABS INTL INC	$26,134,000	-60.4%	63,329	-64.5%	0.26%	-58.9%
NVRO	Buy	NEVRO CORP	$25,017,000	-17.6%	214,956	+17.3%	0.25%	-14.2%
AXSM	Buy	AXSOME THERAPEUTICS INC	$24,817,000	+4.5%	752,945	+113.9%	0.25%	+8.6%
AMWL	Sell	AMERICAN WELL CORPcl a	$19,385,000	-28.1%	2,127,838	-0.6%	0.20%	-25.1%
TMDX	Sell	TRANSMEDICS GROUP INC	$19,226,000	-20.6%	581,029	-20.4%	0.20%	-17.4%
LEGN	Sell	LEGEND BIOTECH CORPsponsored ads	$14,488,000	-9.5%	286,556	-26.6%	0.15%	-5.8%
CVS	Sell	CVS HEALTH CORP	$13,454,000	+0.7%	158,548	-1.0%	0.14%	+5.4%
ZLAB	Buy	ZAI LAB LTDadr	$13,174,000	-39.0%	125,000	+2.5%	0.13%	-36.5%
LH	Buy	LABORATORY CORP AMER HLDGS	$12,412,000	+24.3%	44,100	+21.8%	0.13%	+29.9%
IMAB	Sell	I MABsponsored ads	$11,813,000	-23.3%	162,957	-11.2%	0.12%	-20.0%
OSCR	Sell	OSCAR HEALTH INCcl a	$11,824,000	-20.8%	679,952	-2.0%	0.12%	-17.8%
GILD	Buy	GILEAD SCIENCES INC	$10,966,000	+43.5%	157,000	+41.4%	0.11%	+48.0%
INGN	Sell	INOGEN INC	$10,435,000	-43.0%	242,174	-13.8%	0.11%	-40.8%
SGEN	Buy	SEAGEN INC	$9,067,000	+108.8%	53,400	+94.2%	0.09%	+119.0%
BGNE	Sell	BEIGENE LTDsponsored adr	$8,349,000	-71.1%	23,000	-72.7%	0.08%	-69.9%
AMGN	Sell	AMGEN INC	$7,219,000	-77.1%	33,950	-73.8%	0.07%	-76.3%
GKOS	Sell	GLAUKOS CORP	$6,930,000	-83.5%	143,870	-71.0%	0.07%	-82.9%
	New	SIGHT SCIENCES INC	$6,810,000	–	300,000	–	0.07%	–
	New	PROCEPT BIOROBOTICS CORP	$5,723,000	–	150,000	–	0.06%	–
SYNH	Sell	SYNEOS HEALTH INCcl a	$4,986,000	-21.0%	57,000	-19.1%	0.05%	-17.7%
HRMY	New	HARMONY BIOSCIENCES HLDGS IN	$4,956,000	–	129,289	–	0.05%	–
JNJ	Sell	JOHNSON & JOHNSON	$4,926,000	-3.5%	30,500	-1.6%	0.05%	0.0%
CTLT	Buy	CATALENT INC	$4,791,000	+1540.8%	36,000	+1233.3%	0.05%	+1533.3%
PFE	New	PFIZER INC	$4,284,000	–	99,600	–	0.04%	–
BMRN	Buy	BIOMARIN PHARMACEUTICAL INC	$3,996,000	+18.3%	51,700	+27.7%	0.04%	+24.2%
BNTX	Sell	BIONTECH SEsponsored ads	$3,467,000	-31.5%	12,700	-43.8%	0.04%	-28.6%
RCUS	Buy	ARCUS BIOSCIENCES INC	$3,302,000	+60.3%	94,700	+26.3%	0.03%	+70.0%
MRTX	Buy	MIRATI THERAPEUTICS INC	$3,344,000	+183.6%	18,900	+158.9%	0.03%	+183.3%
NVAX	New	NOVAVAX INC	$3,317,000	–	16,000	–	0.03%	–
SNY	Sell	SANOFIsponsored adr	$3,230,000	-9.8%	67,000	-1.5%	0.03%	-5.7%
BCYC	New	BICYCLE THERAPEUTICS PLCsponsored ads	$2,732,000	–	65,700	–	0.03%	–
RARE	Buy	ULTRAGENYX PHARMACEUTICAL IN	$2,516,000	+23.3%	27,900	+30.4%	0.03%	+30.0%
BHVN	Sell	BIOHAVEN PHARMACTL HLDG CO L	$2,431,000	-30.4%	17,500	-51.4%	0.02%	-26.5%
NTLA	New	INTELLIA THERAPEUTICS INC	$2,226,000	–	16,594	–	0.02%	–
KYMR	New	KYMERA THERAPEUTICS INC	$2,085,000	–	35,500	–	0.02%	–
CCCC	Buy	C4 THERAPEUTICS INC	$2,109,000	+79.8%	47,200	+52.3%	0.02%	+90.9%
CVAC	New	CUREVAC N V	$1,923,000	–	35,200	–	0.02%	–
CDNA	Sell	CAREDX INC	$1,961,000	-85.6%	30,943	-79.2%	0.02%	-85.0%
DGX	New	QUEST DIAGNOSTICS INC	$1,889,000	–	13,000	–	0.02%	–
XNCR	Sell	XENCOR INC	$1,702,000	-7.0%	52,100	-1.9%	0.02%	-5.6%
ARCT	New	ARCTURUS THERAPEUTICS HLDGS	$1,648,000	–	34,500	–	0.02%	–
CLLS	Sell	CELLECTIS S Aspon ads	$1,040,000	-19.5%	82,500	-1.2%	0.01%	-15.4%
KURA	Sell	KURA ONCOLOGY INC	$1,077,000	-10.9%	57,500	-0.9%	0.01%	-8.3%
ACIU	New	AC IMMUNE SA	$933,000	–	139,000	–	0.01%	–
OPT	Sell	OPTHEA LTDsponsored ads	$392,000	-1.3%	49,000	-2.0%	0.00%	0.0%
CVAC	Buy	CUREVAC N Vcall	$1,000	-97.4%	120	+71.4%	0.00%	–
RXRX	Exit	RECURSION PHARMACEUTICALS INcl a	$0	–	-20,000	–	-0.01%	–
ACAD	Exit	ACADIA PHARMACEUTICALS INC	$0	–	-65,900	–	-0.02%	–
DRNA	Exit	DICERNA PHARMACEUTICALS INC	$0	–	-61,000	–	-0.02%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INC	$0	–	-14,300	–	-0.03%	–
SGFY	Exit	SIGNIFY HEALTH INC	$0	–	-200,000	–	-0.06%	–
XENT	Exit	INTERSECT ENT INC	$0	–	-617,968	–	-0.10%	–
EAR	Exit	EARGO INC	$0	–	-434,054	–	-0.17%	–

Q2 2021

			Value		Shares		↓ Weighting
MRNA	New	MODERNA INC	$597,390,000	–	2,542,300	–	5.83%	–
IONS	New	IONIS PHARMACEUTICALS INC	$396,117,000	–	9,930,245	–	3.87%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$349,565,000	–	1,733,694	–	3.41%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$293,688,000	–	3,017,751	–	2.87%	–
ARGX	New	ARGENX SEsponsored adr	$293,254,000	–	974,038	–	2.86%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$262,602,000	–	1,549,092	–	2.56%	–
INCY	New	INCYTE CORP	$249,984,000	–	2,971,400	–	2.44%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$239,893,000	–	4,352,992	–	2.34%	–
FATE	New	FATE THERAPEUTICS INC	$226,829,000	–	2,613,536	–	2.21%	–
MGNX	New	MACROGENICS INC	$198,121,000	–	7,376,026	–	1.93%	–
ISRG	New	INTUITIVE SURGICAL INC	$185,855,000	–	202,095	–	1.81%	–
BIIB	New	BIOGEN INC	$182,865,000	–	528,100	–	1.78%	–
ANTM	New	ANTHEM INC	$177,909,000	–	465,976	–	1.74%	–
ARVN	New	ARVINAS INC	$172,281,000	–	2,237,403	–	1.68%	–
ABT	New	ABBOTT LABS	$159,693,000	–	1,377,499	–	1.56%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$156,529,000	–	966,884	–	1.53%	–
ITCI	New	INTRA-CELLULAR THERAPIES INC	$147,357,000	–	3,609,919	–	1.44%	–
RDUS	New	RADIUS HEALTH INC	$137,373,000	–	7,531,414	–	1.34%	–
UNH	New	UNITEDHEALTH GROUP INC	$137,371,000	–	343,051	–	1.34%	–
SAGE	New	SAGE THERAPEUTICS INC	$134,310,000	–	2,364,204	–	1.31%	–
DHR	New	DANAHER CORPORATION	$129,602,000	–	482,940	–	1.26%	–
HUM	New	HUMANA INC	$125,182,000	–	282,755	–	1.22%	–
MYOV	New	MYOVANT SCIENCES LTD	$119,976,000	–	5,269,039	–	1.17%	–
BDX	New	BECTON DICKINSON & CO	$112,102,000	–	460,965	–	1.09%	–
AXNX	New	AXONICS INC	$109,729,000	–	1,730,471	–	1.07%	–
DXCM	New	DEXCOM INC	$104,519,000	–	244,776	–	1.02%	–
CNC	New	CENTENE CORP DEL	$101,103,000	–	1,386,297	–	0.99%	–
HALO	New	HALOZYME THERAPEUTICS INC	$101,013,000	–	2,224,466	–	0.99%	–
BSX	New	BOSTON SCIENTIFIC CORP	$99,493,000	–	2,326,787	–	0.97%	–
TNDM	New	TANDEM DIABETES CARE INC	$99,384,000	–	1,020,368	–	0.97%	–
SWAV	New	SHOCKWAVE MED INC	$98,074,000	–	516,915	–	0.96%	–
BMY	New	BRISTOL-MYERS SQUIBB CO	$97,786,000	–	1,463,432	–	0.96%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$96,769,000	–	544,750	–	0.94%	–
RLAY	New	RELAY THERAPEUTICS INC	$96,633,000	–	2,640,962	–	0.94%	–
ALGN	New	ALIGN TECHNOLOGY INC	$95,786,000	–	156,770	–	0.94%	–
ESPR	New	ESPERION THERAPEUTICS INC NE	$95,580,000	–	4,519,164	–	0.93%	–
ACCD	New	ACCOLADE INC	$93,668,000	–	1,724,699	–	0.91%	–
EW	New	EDWARDS LIFESCIENCES CORP	$92,204,000	–	890,256	–	0.90%	–
SYK	New	STRYKER CORPORATION	$89,481,000	–	344,514	–	0.87%	–
INSM	New	INSMED INC	$88,821,000	–	3,120,901	–	0.87%	–
PODD	New	INSULET CORP	$88,425,000	–	322,119	–	0.86%	–
BEAM	New	BEAM THERAPEUTICS INC	$78,876,000	–	612,821	–	0.77%	–
EVH	New	EVOLENT HEALTH INCcl a	$76,843,000	–	3,638,411	–	0.75%	–
HRC	New	HILL-ROM HLDGS INC	$76,546,000	–	673,878	–	0.75%	–
MTEM	New	MOLECULAR TEMPLATES INC	$75,296,000	–	9,628,621	–	0.74%	–
IDXX	New	IDEXX LABS INC	$74,599,000	–	118,120	–	0.73%	–
BAX	New	BAXTER INTL INC	$72,500,000	–	900,623	–	0.71%	–
INSP	New	INSPIRE MED SYS INC	$72,130,000	–	373,226	–	0.70%	–
NKTR	New	NEKTAR THERAPEUTICS	$70,380,000	–	4,101,404	–	0.69%	–
EPIX	New	ESSA PHARMA INC	$70,277,000	–	2,459,814	–	0.69%	–
HCA	New	HCA HEALTHCARE INC	$69,108,000	–	334,273	–	0.68%	–
GBIO	New	GENERATION BIO CO	$66,664,000	–	2,478,180	–	0.65%	–
SRRK	New	SCHOLAR ROCK HLDG CORP	$66,401,000	–	2,297,625	–	0.65%	–
CRL	New	CHARLES RIV LABS INTL INC	$65,946,000	–	178,270	–	0.64%	–
SILK	New	SILK RD MED INC	$61,920,000	–	1,293,759	–	0.60%	–
HOLX	New	HOLOGIC INC	$60,965,000	–	913,752	–	0.60%	–
CI	New	CIGNA CORP NEW	$60,866,000	–	256,742	–	0.59%	–
OMCL	New	OMNICELL INC	$59,608,000	–	393,583	–	0.58%	–
REGN	New	REGENERON PHARMACEUTICALS	$59,015,000	–	105,660	–	0.58%	–
RVMD	New	REVOLUTION MEDICINES INC	$58,871,000	–	1,854,805	–	0.58%	–
PACB	New	PACIFIC BIOSIENCES CALIF IN	$57,461,000	–	1,643,159	–	0.56%	–
GMED	New	GLOBUS MED INCcl a	$56,552,000	–	729,420	–	0.55%	–
BIO	New	BIO RAD LABS INCcl a	$56,247,000	–	87,301	–	0.55%	–
VEEV	New	VEEVA SYS INC	$53,685,000	–	172,647	–	0.52%	–
EXEL	New	EXELIXIS INC	$53,421,000	–	2,932,000	–	0.52%	–
MOH	New	MOLINA HEALTHCARE INC	$50,292,000	–	198,734	–	0.49%	–
PEN	New	PENUMBRA INC	$49,913,000	–	182,125	–	0.49%	–
ABMD	New	ABIOMED INC	$47,184,000	–	151,178	–	0.46%	–
GH	New	GUARDANT HEALTH INC	$47,144,000	–	379,609	–	0.46%	–
TXG	New	10X GENOMICS INC	$45,562,000	–	232,672	–	0.44%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$45,043,000	–	280,082	–	0.44%	–
MDT	New	MEDTRONIC PLC	$44,640,000	–	359,625	–	0.44%	–
IQV	New	IQVIA HLDGS INC	$42,988,000	–	177,400	–	0.42%	–
TDOC	New	TELADOC HEALTH INC	$42,894,000	–	257,948	–	0.42%	–
BDTX	New	BLACK DIAMOND THERAPEUTICS I	$42,214,000	–	3,463,000	–	0.41%	–
GKOS	New	GLAUKOS CORP	$42,027,000	–	495,432	–	0.41%	–
HCAT	New	HEALTH CATALYST INC	$41,834,000	–	753,621	–	0.41%	–
TFX	New	TELEFLEX INCORPORATED	$40,244,000	–	100,161	–	0.39%	–
MRSN	New	MERSANA THERAPEUTICS INC	$39,939,000	–	2,941,000	–	0.39%	–
ADPT	New	ADAPTIVE BIOTECHNOLOGIES COR	$39,322,000	–	962,352	–	0.38%	–
OPCH	New	OPTION CARE HEALTH INC	$39,151,000	–	1,790,192	–	0.38%	–
HZNP	New	HORIZON THERAPEUTICS PUB L	$39,113,000	–	417,700	–	0.38%	–
PHR	New	PHREESIA INC	$38,162,000	–	622,542	–	0.37%	–
QTRX	New	QUANTERIX CORP	$37,414,000	–	637,815	–	0.36%	–
NEO	New	NEOGENOMICS INC	$36,963,000	–	818,313	–	0.36%	–
ABBV	New	ABBVIE INC	$36,518,000	–	324,200	–	0.36%	–
ILMN	New	ILLUMINA INC	$35,647,000	–	75,330	–	0.35%	–
EXAS	New	EXACT SCIENCES CORP	$34,269,000	–	275,673	–	0.34%	–
HCM	New	HUTCHMED CHINA LTDsponsored ads	$33,959,000	–	864,760	–	0.33%	–
AMGN	New	AMGEN INC	$31,585,000	–	129,580	–	0.31%	–
MASI	New	MASIMO CORP	$30,964,000	–	127,713	–	0.30%	–
NVRO	New	NEVRO CORP	$30,373,000	–	183,201	–	0.30%	–
ATRC	New	ATRICURE INC	$29,703,000	–	374,418	–	0.29%	–
COO	New	COOPER COS INC	$29,429,000	–	74,266	–	0.29%	–
BGNE	New	BEIGENE LTDsponsored adr	$28,931,000	–	84,300	–	0.28%	–
ONEM	New	1LIFE HEALTHCARE INC	$27,644,000	–	836,190	–	0.27%	–
AMWL	New	AMERICAN WELL CORPcl a	$26,943,000	–	2,141,758	–	0.26%	–
VCRA	New	VOCERA COMMUNICATONS INC	$26,015,000	–	652,832	–	0.25%	–
BHG	New	BRIGHT HEALTH GROUP INC	$25,740,000	–	1,500,000	–	0.25%	–
KZR	New	KEZAR LIFE SCIENCES INC	$24,615,000	–	4,533,148	–	0.24%	–
TMDX	New	TRANSMEDICS GROUP INC	$24,221,000	–	729,989	–	0.24%	–
AXSM	New	AXSOME THERAPEUTICS INC	$23,747,000	–	352,021	–	0.23%	–
PRVA	New	PRIVIA HEALTH GROUP INC	$23,294,000	–	525,000	–	0.23%	–
OM	New	OUTSET MED INC	$22,844,000	–	457,060	–	0.22%	–
RMD	New	RESMED INC	$21,730,000	–	88,145	–	0.21%	–
ZLAB	New	ZAI LAB LTDadr	$21,593,000	–	122,000	–	0.21%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$21,175,000	–	41,974	–	0.21%	–
INGN	New	INOGEN INC	$18,304,000	–	280,863	–	0.18%	–
AVTR	New	AVANTOR INC	$18,189,000	–	512,216	–	0.18%	–
WVE	New	WAVE LIFE SCIENCES LTD	$17,335,000	–	2,602,858	–	0.17%	–
EAR	New	EARGO INC	$17,323,000	–	434,054	–	0.17%	–
BLI	New	BERKELEY LTS INC	$17,252,000	–	385,014	–	0.17%	–
LEGN	New	LEGEND BIOTECH CORPsponsored ads	$16,016,000	–	390,163	–	0.16%	–
IMAB	New	I MABsponsored ads	$15,401,000	–	183,457	–	0.15%	–
OSCR	New	OSCAR HEALTH INCcl a	$14,924,000	–	694,136	–	0.15%	–
AMED	New	AMEDISYS INC	$14,815,000	–	60,487	–	0.14%	–
GTH	New	GENETRON HLDGS LTDads	$14,564,000	–	723,137	–	0.14%	–
BNR	New	BURNING ROCK BIOTECH LTDsponsored adr	$14,432,000	–	489,890	–	0.14%	–
CDNA	New	CAREDX INC	$13,625,000	–	148,871	–	0.13%	–
CVS	New	CVS HEALTH CORP	$13,363,000	–	160,148	–	0.13%	–
FIXX	New	HOMOLOGY MEDICINES INC	$12,629,000	–	1,737,122	–	0.12%	–
NPCE	New	NEUROPACE INC	$12,084,000	–	507,930	–	0.12%	–
XENT	New	INTERSECT ENT INC	$10,561,000	–	617,968	–	0.10%	–
XRAY	New	DENTSPLY SIRONA INC	$10,067,000	–	159,129	–	0.10%	–
LH	New	LABORATORY CORP AMER HLDGS	$9,986,000	–	36,200	–	0.10%	–
LUNG	New	PULMONX CORP	$7,788,000	–	176,510	–	0.08%	–
GILD	New	GILEAD SCIENCES INC	$7,643,000	–	111,000	–	0.08%	–
OLK	New	OLINK HLDG ABsponsored ads	$6,799,000	–	197,527	–	0.07%	–
SYNH	New	SYNEOS HEALTH INCcl a	$6,309,000	–	70,500	–	0.06%	–
SGFY	New	SIGNIFY HEALTH INC	$6,086,000	–	200,000	–	0.06%	–
JNJ	New	JOHNSON & JOHNSON	$5,107,000	–	31,000	–	0.05%	–
BNTX	New	BIONTECH SEsponsored ads	$5,060,000	–	22,600	–	0.05%	–
SEER	New	SEER INC	$4,462,000	–	136,133	–	0.04%	–
SGEN	New	SEAGEN INC	$4,342,000	–	27,500	–	0.04%	–
SNY	New	SANOFIsponsored adr	$3,581,000	–	68,000	–	0.04%	–
BHVN	New	BIOHAVEN PHARMACTL HLDG CO L	$3,495,000	–	36,000	–	0.03%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$3,379,000	–	40,500	–	0.03%	–
APLS	New	APELLIS PHARMACEUTICALS INC	$3,034,000	–	48,000	–	0.03%	–
ALXN	New	ALEXION PHARMACEUTICALS INC	$2,627,000	–	14,300	–	0.03%	–
DRNA	New	DICERNA PHARMACEUTICALS INC	$2,277,000	–	61,000	–	0.02%	–
RCUS	New	ARCUS BIOSCIENCES INC	$2,060,000	–	75,000	–	0.02%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL IN	$2,040,000	–	21,400	–	0.02%	–
XNCR	New	XENCOR INC	$1,831,000	–	53,100	–	0.02%	–
ACAD	New	ACADIA PHARMACEUTICALS INC	$1,607,000	–	65,900	–	0.02%	–
ALLK	New	ALLAKOS INC	$1,579,000	–	18,500	–	0.02%	–
ZTS	New	ZOETIS INCcl a	$1,323,000	–	7,100	–	0.01%	–
CLLS	New	CELLECTIS S Aspon ads	$1,292,000	–	83,500	–	0.01%	–
MRTX	New	MIRATI THERAPEUTICS INC	$1,179,000	–	7,300	–	0.01%	–
KURA	New	KURA ONCOLOGY INC	$1,209,000	–	58,000	–	0.01%	–
CCCC	New	C4 THERAPEUTICS INC	$1,173,000	–	31,000	–	0.01%	–
KOS	New	KOSMOS ENERGY LTD	$1,010,000	–	292,000	–	0.01%	–
RXRX	New	RECURSION PHARMACEUTICALS INcl a	$730,000	–	20,000	–	0.01%	–
RDY	New	DR REDDYS LABS LTDadr	$625,000	–	8,500	–	0.01%	–
MCK	New	MCKESSON CORP	$465,000	–	2,430	–	0.01%	–
DPZ	New	DOMINOS PIZZA INC	$466,000	–	1,000	–	0.01%	–
JMIA	New	JUMIA TECHNOLOGIES AGsponsored ads	$546,000	–	18,000	–	0.01%	–
IT	New	GARTNER INC	$509,000	–	2,100	–	0.01%	–
FTNT	New	FORTINET INC	$524,000	–	2,200	–	0.01%	–
SPGI	New	S&P GLOBAL INC	$493,000	–	1,200	–	0.01%	–
POOL	New	POOL CORP	$413,000	–	900	–	0.00%	–
ENTG	New	ENTEGRIS INC	$369,000	–	3,000	–	0.00%	–
FAST	New	FASTENAL CO	$364,000	–	7,000	–	0.00%	–
TRU	New	TRANSUNION	$406,000	–	3,696	–	0.00%	–
AVLR	New	AVALARA INC	$372,000	–	2,300	–	0.00%	–
INTU	New	INTUIT	$441,000	–	900	–	0.00%	–
WSO	New	WATSCO INC	$373,000	–	1,300	–	0.00%	–
OPT	New	OPTHEA LTDsponsored ads	$397,000	–	50,000	–	0.00%	–
EL	New	LAUDER ESTEE COS INCcl a	$429,000	–	1,348	–	0.00%	–
LYV	New	LIVE NATION ENTERTAINMENT IN	$412,000	–	4,700	–	0.00%	–
VRSN	New	VERISIGN INC	$387,000	–	1,700	–	0.00%	–
MSCI	New	MSCI INC	$435,000	–	816	–	0.00%	–
AXP	New	AMERICAN EXPRESS CO	$430,000	–	2,600	–	0.00%	–
SWKS	New	SKYWORKS SOLUTIONS INC	$403,000	–	2,100	–	0.00%	–
SBUX	New	STARBUCKS CORP	$362,000	–	3,234	–	0.00%	–
A	New	AGILENT TECHNOLOGIES INC	$399,000	–	2,700	–	0.00%	–
MCO	New	MOODYS CORP	$453,000	–	1,250	–	0.00%	–
MTCH	New	MATCH GROUP INC NEW	$383,000	–	2,378	–	0.00%	–
CLX	New	CLOROX CO DEL	$360,000	–	2,000	–	0.00%	–
MTD	New	METTLER TOLEDO INTERNATIONAL	$374,000	–	270	–	0.00%	–
TRMB	New	TRIMBLE INC	$393,000	–	4,800	–	0.00%	–
ULTA	New	ULTA BEAUTY INC	$380,000	–	1,100	–	0.00%	–
TW	New	TRADEWEB MKTS INCcl a	$440,000	–	5,200	–	0.00%	–
TYL	New	TYLER TECHNOLOGIES INC	$362,000	–	800	–	0.00%	–
KMX	New	CARMAX INC	$368,000	–	2,850	–	0.00%	–
AZPN	New	ASPEN TECHNOLOGY INC	$330,000	–	2,400	–	0.00%	–
DLB	New	DOLBY LABORATORIES INC	$354,000	–	3,600	–	0.00%	–
FDS	New	FACTSET RESH SYS INC	$352,000	–	1,050	–	0.00%	–
CSGP	New	COSTAR GROUP INC	$290,000	–	3,500	–	0.00%	–
GGG	New	GRACO INC	$341,000	–	4,500	–	0.00%	–
STZ	New	CONSTELLATION BRANDS INCcl a	$341,000	–	1,459	–	0.00%	–
CTLT	New	CATALENT INC	$292,000	–	2,700	–	0.00%	–
IPGP	New	IPG PHOTONICS CORP	$285,000	–	1,350	–	0.00%	–
ICE	New	INTERCONTINENTAL EXCHANGE IN	$356,000	–	3,000	–	0.00%	–
BFB	New	BROWN FORMAN CORPcl b	$345,000	–	4,600	–	0.00%	–
BKNG	New	BOOKING HOLDINGS INC	$350,000	–	160	–	0.00%	–
JD	New	JD.COM INCspon adr cl a	$287,000	–	3,600	–	0.00%	–
MKL	New	MARKEL CORP	$356,000	–	300	–	0.00%	–
MKTX	New	MARKETAXESS HLDGS INC	$307,000	–	662	–	0.00%	–
MKC	New	MCCORMICK & CO INC	$353,000	–	4,000	–	0.00%	–
MELI	New	MERCADOLIBRE INC	$265,000	–	170	–	0.00%	–
NYT	New	NEW YORK TIMES COcl a	$327,000	–	7,500	–	0.00%	–
PKI	New	PERKINELMER INC	$340,000	–	2,200	–	0.00%	–
EA	New	ELECTRONIC ARTS INC	$326,000	–	2,270	–	0.00%	–
ANSS	New	ANSYS INC	$312,000	–	900	–	0.00%	–
SCI	New	SERVICE CORP INTL	$348,000	–	6,500	–	0.00%	–
TCOM	New	TRIP COM GROUP LTDads	$355,000	–	10,000	–	0.00%	–
OLED	New	UNIVERSAL DISPLAY CORP	$303,000	–	1,365	–	0.00%	–
VRSK	New	VERISK ANALYTICS INC	$304,000	–	1,739	–	0.00%	–
WAB	New	WABTEC	$346,000	–	4,200	–	0.00%	–
ST	New	SENSATA TECHNOLOGIES HLDNG PL	$342,000	–	5,900	–	0.00%	–
STNE	New	STONECO LTD	$288,000	–	4,300	–	0.00%	–
SPOT	New	SPOTIFY TECHNOLOGY SA	$303,000	–	1,100	–	0.00%	–
CYBR	New	CYBERARK SOFTWARE LTD	$274,000	–	2,100	–	0.00%	–
CVAC	New	CUREVAC N Vcall	$39,000	–	70	–	0.00%	–

Q4 2020

			Value		Shares		↓ Weighting
CVET	Exit	COVETRUS INC	$0	–	-1,520	–	-0.00%	–
BLKB	Exit	BLACKBAUD INC	$0	–	-4,107	–	-0.00%	–
BKNG	Exit	BOOKING HOLDINGS INC	$0	–	-200	–	-0.01%	–
MKTX	Exit	MARKETAXESS HLDGS INC	$0	–	-822	–	-0.01%	–
TW	Exit	TRADEWEB MKTS INCcl a	$0	–	-6,800	–	-0.01%	–
SBUX	Exit	STARBUCKS CORP	$0	–	-4,334	–	-0.01%	–
AZPN	Exit	ASPEN TECHNOLOGY INC	$0	–	-3,000	–	-0.01%	–
WAB	Exit	WABTEC	$0	–	-6,400	–	-0.01%	–
AXP	Exit	AMERICAN EXPRESS CO	$0	–	-3,600	–	-0.01%	–
STZ	Exit	CONSTELLATION BRANDS INCcl a	$0	–	-2,059	–	-0.01%	–
SCI	Exit	SERVICE CORP INTL	$0	–	-8,500	–	-0.01%	–
AVNT	Exit	AVIENT CORPORATION	$0	–	-13,600	–	-0.01%	–
MKL	Exit	MARKEL CORP	$0	–	-400	–	-0.01%	–
FTNT	Exit	FORTINET INC	$0	–	-2,900	–	-0.01%	–
LYV	Exit	LIVE NATION ENTERTAINMENT IN	$0	–	-6,200	–	-0.01%	–
XLNX	Exit	XILINX INC	$0	–	-4,200	–	-0.01%	–
TRU	Exit	TRANSUNION	$0	–	-5,096	–	-0.01%	–
MSCI	Exit	MSCI INC	$0	–	-1,186	–	-0.01%	–
IT	Exit	GARTNER INC	$0	–	-3,400	–	-0.01%	–
VRSK	Exit	VERISK ANALYTICS INC	$0	–	-2,489	–	-0.01%	–
PAYX	Exit	PAYCHEX INC	$0	–	-5,400	–	-0.01%	–
CYBR	Exit	CYBERARK SOFTWARE LTD	$0	–	-4,300	–	-0.01%	–
IQV	Exit	IQVIA HLDGS INC	$0	–	-2,900	–	-0.01%	–
CLX	Exit	CLOROX CO DEL	$0	–	-2,000	–	-0.01%	–
DPZ	Exit	DOMINOS PIZZA INC	$0	–	-1,000	–	-0.01%	–
IPGP	Exit	IPG PHOTONICS CORP	$0	–	-2,700	–	-0.01%	–
KOS	Exit	KOSMOS ENERGY LTD	$0	–	-425,000	–	-0.01%	–
ST	Exit	SENSATA TECHNOLOGIES HLDNG P	$0	–	-9,900	–	-0.01%	–
TCOM	Exit	TRIP COM GROUP LTDads	$0	–	-13,100	–	-0.01%	–
BR	Exit	BROADRIDGE FINL SOLUTIONS IN	$0	–	-3,400	–	-0.01%	–
IBKR	Exit	INTERACTIVE BROKERS GROUP IN	$0	–	-9,400	–	-0.01%	–
VRSN	Exit	VERISIGN INC	$0	–	-2,100	–	-0.01%	–
FAST	Exit	FASTENAL CO	$0	–	-10,000	–	-0.01%	–
ULTA	Exit	ULTA BEAUTY INC	$0	–	-2,000	–	-0.01%	–
CTLT	Exit	CATALENT INC	$0	–	-5,700	–	-0.01%	–
ICE	Exit	INTERCONTINENTAL EXCHANGE IN	$0	–	-4,800	–	-0.01%	–
TYL	Exit	TYLER TECHNOLOGIES INC	$0	–	-1,525	–	-0.01%	–
EL	Exit	LAUDER ESTEE COS INCcl a	$0	–	-2,248	–	-0.01%	–
ADBE	Exit	ADOBE SYSTEMS INCORPORATED	$0	–	-1,100	–	-0.01%	–
ADI	Exit	ANALOG DEVICES INC	$0	–	-4,100	–	-0.01%	–
MELI	Exit	MERCADOLIBRE INC	$0	–	-500	–	-0.01%	–
ALV	Exit	AUTOLIV INC	$0	–	-6,800	–	-0.01%	–
SWKS	Exit	SKYWORKS SOLUTIONS INC	$0	–	-3,700	–	-0.01%	–
MTCH	Exit	MATCH GROUP INC NEW	$0	–	-5,478	–	-0.01%	–
EA	Exit	ELECTRONIC ARTS INC	$0	–	-4,670	–	-0.01%	–
SPGI	Exit	S&P GLOBAL INC	$0	–	-1,700	–	-0.01%	–
ANSS	Exit	ANSYS INC	$0	–	-1,802	–	-0.01%	–
MCK	Exit	MCKESSON CORP	$0	–	-3,892	–	-0.01%	–
ENTG	Exit	ENTEGRIS INC	$0	–	-7,300	–	-0.01%	–
PKI	Exit	PERKINELMER INC	$0	–	-4,800	–	-0.01%	–
GGG	Exit	GRACO INC	$0	–	-9,700	–	-0.01%	–
STNE	Exit	STONECO LTD	$0	–	-10,700	–	-0.01%	–
SQM	Exit	SOCIEDAD QUIMICA Y MINERA DEspon adr ser b	$0	–	-18,200	–	-0.01%	–
CSGP	Exit	COSTAR GROUP INC	$0	–	-700	–	-0.01%	–
MCO	Exit	MOODYS CORP	$0	–	-2,000	–	-0.01%	–
RDY	Exit	DR REDDYS LABS LTDadr	$0	–	-8,500	–	-0.01%	–
FDS	Exit	FACTSET RESH SYS INC	$0	–	-1,700	–	-0.01%	–
BFB	Exit	BROWN FORMAN CORPcl b	$0	–	-7,600	–	-0.01%	–
HTHT	Exit	HUAZHU GROUP LTDsponsored ads	$0	–	-13,500	–	-0.01%	–
MKC	Exit	MCCORMICK & CO INC	$0	–	-2,800	–	-0.01%	–
TRMB	Exit	TRIMBLE INC	$0	–	-11,700	–	-0.01%	–
WSO	Exit	WATSCO INC	$0	–	-2,800	–	-0.01%	–
JD	Exit	JD.COM INCspon adr cl a	$0	–	-8,700	–	-0.01%	–
A	Exit	AGILENT TECHNOLOGIES INC	$0	–	-6,200	–	-0.01%	–
MTD	Exit	METTLER TOLEDO INTERNATIONAL	$0	–	-700	–	-0.01%	–
POOL	Exit	POOL CORP	$0	–	-2,200	–	-0.01%	–
VAR	Exit	VARIAN MED SYS INC	$0	–	-4,100	–	-0.01%	–
QURE	Exit	UNIQURE NV	$0	–	-34,500	–	-0.02%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-48,000	–	-0.02%	–
CLLS	Exit	CELLECTIS S Aspon ads	$0	–	-83,500	–	-0.02%	–
BHVN	Exit	BIOHAVEN PHARMACTL HLDG CO L	$0	–	-24,500	–	-0.02%	–
BMYRT	Exit	BRISTOL MYERS SQUIBB COright 99/99/9999	$0	–	-800,000	–	-0.02%	–
ACAD	Exit	ACADIA PHARMACEUTICALS INC	$0	–	-44,900	–	-0.03%	–
GTH	Exit	GENETRON HLDGS LTDads	$0	–	-160,410	–	-0.03%	–
FGEN	Exit	FIBROGEN INC	$0	–	-53,000	–	-0.03%	–
CVAC	Exit	CUREVAC NV	$0	–	-50,500	–	-0.03%	–
ASND	Exit	ASCENDIS PHARMA A Ssponsored adr	$0	–	-15,500	–	-0.03%	–
BIIB	Exit	BIOGEN INC	$0	–	-8,600	–	-0.03%	–
PFE	Exit	PFIZER INC	$0	–	-73,900	–	-0.04%	–
SRPT	Exit	SAREPTA THERAPEUTICS INC	$0	–	-20,300	–	-0.04%	–
SNY	Exit	SANOFIsponsored adr	$0	–	-57,000	–	-0.04%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-17,800	–	-0.04%	–
IMAB	Exit	I MABsponsored ads	$0	–	-65,000	–	-0.04%	–
ABBV	Exit	ABBVIE INC	$0	–	-37,000	–	-0.04%	–
BNTX	Exit	BIONTECH SEsponsored ads	$0	–	-49,500	–	-0.05%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL IN	$0	–	-41,000	–	-0.05%	–
BNR	Exit	BURNING ROCK BIOTECH LTDsponsored adr	$0	–	-146,761	–	-0.05%	–
NUVA	Exit	NUVASIVE INC	$0	–	-82,100	–	-0.06%	–
OM	Exit	OUTSET MED INC	$0	–	-79,921	–	-0.06%	–
GOCO	Exit	GOHEALTH INC	$0	–	-314,672	–	-0.06%	–
INGN	Exit	INOGEN INC	$0	–	-148,912	–	-0.06%	–
QTNT	Exit	QUOTIENT LTD	$0	–	-917,074	–	-0.06%	–
IART	Exit	INTEGRA LIFESCIENCES HLDGS C	$0	–	-122,426	–	-0.08%	–
VCRA	Exit	VOCERA COMMUNICATONS INC	$0	–	-201,390	–	-0.08%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB LTD	$0	–	-77,400	–	-0.08%	–
AKCA	Exit	AKCEA THERAPEUTICS INC	$0	–	-340,264	–	-0.08%	–
AVTR	Exit	AVANTOR INC	$0	–	-307,089	–	-0.10%	–
DGX	Exit	QUEST DIAGNOSTICS INC	$0	–	-60,005	–	-0.10%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-159,129	–	-0.10%	–
XENT	Exit	INTERSECT ENT INC	$0	–	-473,382	–	-0.11%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-123,700	–	-0.11%	–
TMDX	Exit	TRANSMEDICS GROUP INC	$0	–	-577,147	–	-0.11%	–
CDTX	Exit	CIDARA THERAPEUTICS INC	$0	–	-2,822,495	–	-0.11%	–
ACCD	Exit	ACCOLADE INC	$0	–	-209,327	–	-0.11%	–
BLI	Exit	BERKELEY LTS INC	$0	–	-107,510	–	-0.11%	–
GTHX	Exit	G1 THERAPEUTICS INC	$0	–	-721,925	–	-0.12%	–
COO	Exit	COOPER COS INC	$0	–	-25,345	–	-0.12%	–
SGEN	Exit	SEATTLE GENETICS INC	$0	–	-46,600	–	-0.13%	–
OXFD	Exit	OXFORD IMMUNOTEC GLOBAL PLC	$0	–	-800,157	–	-0.13%	–
TRHC	Exit	TABULA RASA HEALTHCARE INC	$0	–	-244,469	–	-0.14%	–
LH	Exit	LABORATORY CORP AMER HLDGS	$0	–	-54,234	–	-0.14%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-186,981	–	-0.15%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-20,000	–	-0.16%	–
AMWL	Exit	AMERICAN WELL CORPcl a	$0	–	-379,854	–	-0.16%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-39,400	–	-0.16%	–
RMD	Exit	RESMED INC	$0	–	-77,805	–	-0.18%	–
ONEM	Exit	1LIFE HEALTHCARE INC	$0	–	-468,564	–	-0.18%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-161,200	–	-0.18%	–
PHR	Exit	PHREESIA INC	$0	–	-426,956	–	-0.19%	–
AMED	Exit	AMEDISYS INC	$0	–	-61,851	–	-0.20%	–
NEO	Exit	NEOGENOMICS INC	$0	–	-426,892	–	-0.22%	–
NVRO	Exit	NEVRO CORP	$0	–	-120,569	–	-0.23%	–
GNMK	Exit	GENMARK DIAGNOSTICS INC	$0	–	-1,263,811	–	-0.25%	–
ILMN	Exit	ILLUMINA INC	$0	–	-58,547	–	-0.25%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-162,383	–	-0.25%	–
FIXX	Exit	HOMOLOGY MEDICINES INC	$0	–	-1,737,122	–	-0.26%	–
HCAT	Exit	HEALTH CATALYST INC	$0	–	-521,896	–	-0.26%	–
TXG	Exit	10X GENOMICS INC	$0	–	-153,989	–	-0.26%	–
SILK	Exit	SILK RD MED INC	$0	–	-300,619	–	-0.28%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-409,735	–	-0.28%	–
OMCL	Exit	OMNICELL INC	$0	–	-278,421	–	-0.29%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-90,518	–	-0.30%	–
HMSY	Exit	HMS HLDGS CORP	$0	–	-916,984	–	-0.30%	–
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-4,533,148	–	-0.30%	–
WVE	Exit	WAVE LIFE SCIENCES LTD	$0	–	-2,602,858	–	-0.30%	–
PEN	Exit	PENUMBRA INC	$0	–	-121,194	–	-0.33%	–
MASI	Exit	MASIMO CORP	$0	–	-102,153	–	-0.33%	–
QTRX	Exit	QUANTERIX CORP	$0	–	-723,674	–	-0.34%	–
CHNG	Exit	CHANGE HEALTHCARE INC	$0	–	-1,697,939	–	-0.34%	–
GKOS	Exit	GLAUKOS CORP	$0	–	-515,754	–	-0.35%	–
CHRS	Exit	COHERUS BIOSCIENCES INC	$0	–	-1,403,400	–	-0.36%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-121,354	–	-0.37%	–
TFX	Exit	TELEFLEX INCORPORATED	$0	–	-78,644	–	-0.37%	–
VEEV	Exit	VEEVA SYS INC	$0	–	-95,367	–	-0.37%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-84,635	–	-0.38%	–
DVA	Exit	DAVITA INC	$0	–	-326,400	–	-0.39%	–
ABMD	Exit	ABIOMED INC	$0	–	-101,398	–	-0.39%	–
LVGO	Exit	LIVONGO HEALTH INC	$0	–	-203,329	–	-0.39%	–
VYGR	Exit	VOYAGER THERAPEUTICS INC	$0	–	-2,712,083	–	-0.40%	–
ICPT	Exit	INTERCEPT PHARMACEUTICALS IN	$0	–	-704,976	–	-0.40%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-164,572	–	-0.42%	–
HCM	Exit	HUTCHISON CHINA MEDITECH LTDsponsored adr	$0	–	-947,674	–	-0.42%	–
ZBH	Exit	ZIMMER BIOMET HOLDINGS INC	$0	–	-225,740	–	-0.42%	–
IDXX	Exit	IDEXX LABS INC	$0	–	-78,398	–	-0.43%	–
EXAS	Exit	EXACT SCIENCES CORP	$0	–	-304,490	–	-0.43%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-70,865	–	-0.43%	–
AXNX	Exit	AXONICS MODULATION TECHNOLOG	$0	–	-644,944	–	-0.46%	–
SWAV	Exit	SHOCKWAVE MED INC	$0	–	-461,253	–	-0.48%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-272,983	–	-0.49%	–
TNDM	Exit	TANDEM DIABETES CARE INC	$0	–	-313,444	–	-0.49%	–
SGMO	Exit	SANGAMO THERAPEUTICS INC	$0	–	-3,850,000	–	-0.50%	–
BAX	Exit	BAXTER INTL INC	$0	–	-474,623	–	-0.53%	–
PACB	Exit	PACIFIC BIOSIENCES CALIF IN	$0	–	-3,904,467	–	-0.53%	–
ARVN	Exit	ARVINAS INC	$0	–	-1,641,503	–	-0.54%	–
INSM	Exit	INSMED INC	$0	–	-1,220,169	–	-0.54%	–
BIO	Exit	BIO RAD LABS INCcl a	$0	–	-78,186	–	-0.56%	–
EVH	Exit	EVOLENT HEALTH INCcl a	$0	–	-3,273,325	–	-0.56%	–
CDNA	Exit	CAREDX INC	$0	–	-1,115,903	–	-0.58%	–
BDTX	Exit	BLACK DIAMOND THERAPEUTICS I	$0	–	-1,403,000	–	-0.59%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-345,085	–	-0.59%	–
AMGN	Exit	AMGEN INC	$0	–	-179,613	–	-0.63%	–
HOLX	Exit	HOLOGIC INC	$0	–	-696,980	–	-0.64%	–
HRC	Exit	HILL ROM HLDGS INC	$0	–	-571,069	–	-0.66%	–
DXCM	Exit	DEXCOM INC	$0	–	-121,705	–	-0.69%	–
SRRK	Exit	SCHOLAR ROCK HLDG CORP	$0	–	-2,842,515	–	-0.70%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-356,350	–	-0.70%	–
GWPH	Exit	GW PHARMACEUTICALS PLCads	$0	–	-562,943	–	-0.76%	–
MTEM	Exit	MOLECULAR TEMPLATES INC	$0	–	-5,021,996	–	-0.76%	–
RLAY	Exit	RELAY THERAPEUTICS INC	$0	–	-1,300,000	–	-0.76%	–
CI	Exit	CIGNA CORP NEW	$0	–	-335,737	–	-0.79%	–
GBIO	Exit	GENERATION BIO CO	$0	–	-1,880,000	–	-0.80%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-3,632,358	–	-0.83%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-1,033,647	–	-0.83%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-260,846	–	-0.84%	–
PODD	Exit	INSULET CORP	$0	–	-269,875	–	-0.88%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-827,818	–	-0.91%	–
SYK	Exit	STRYKER CORPORATION	$0	–	-322,771	–	-0.93%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-5,092,000	–	-0.99%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-1,886,297	–	-1.00%	–
EXEL	Exit	EXELIXIS INC	$0	–	-3,073,500	–	-1.04%	–
CRSP	Exit	CRISPR THERAPEUTICS AGnamen akt	$0	–	-949,262	–	-1.10%	–
CRL	Exit	CHARLES RIV LABS INTL INC	$0	–	-351,083	–	-1.10%	–
RDUS	Exit	RADIUS HEALTH INC	$0	–	-7,431,414	–	-1.16%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-831,450	–	-1.19%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-2,217,500	–	-1.22%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-3,579,919	–	-1.27%	–
ANTM	Exit	ANTHEM INC	$0	–	-349,123	–	-1.30%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-1,579,504	–	-1.33%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-453,384	–	-1.35%	–
BMY	Exit	BRISTOL MYERS SQUIBB CO	$0	–	-1,645,912	–	-1.37%	–
HUM	Exit	HUMANA INC	$0	–	-243,996	–	-1.40%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-324,053	–	-1.40%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-153,184	–	-1.50%	–
MGNX	Exit	MACROGENICS INC	$0	–	-5,282,188	–	-1.84%	–
ABT	Exit	ABBOTT LABS	$0	–	-1,288,285	–	-1.94%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-5,469,131	–	-1.99%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-4,151,002	–	-2.01%	–
MYOK	Exit	MYOKARDIA INC	$0	–	-1,128,400	–	-2.13%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INC	$0	–	-1,421,128	–	-2.25%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NEW	$0	–	-5,465,715	–	-2.81%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-1,559,805	–	-3.14%	–
MRNA	Exit	MODERNA INC	$0	–	-3,341,950	–	-3.27%	–
ARGX	Exit	ARGENX SEsponsored adr	$0	–	-959,016	–	-3.48%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-960,600	–	-3.61%	–
INCY	Exit	INCYTE CORP	$0	–	-3,279,450	–	-4.07%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-3,297,451	–	-4.38%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-8,716,270	–	-5.72%	–

Q3 2020

			Value		Shares		↓ Weighting
IONS	Buy	IONIS PHARMACEUTICALS INC	$413,588,000	-15.0%	8,716,270	+5.7%	5.72%	-17.0%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$317,083,000	-19.1%	3,297,451	+2.7%	4.38%	-21.0%
INCY	Sell	INCYTE CORP	$294,298,000	-14.0%	3,279,450	-0.4%	4.07%	-16.1%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$261,398,000	-8.4%	960,600	-2.2%	3.61%	-10.5%
ARGX	Buy	ARGENX SEsponsored adr	$251,761,000	+17.2%	959,016	+0.5%	3.48%	+14.4%
MRNA	Sell	MODERNA INC	$236,443,000	+10.1%	3,341,950	-0.1%	3.27%	+7.5%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$227,108,000	-4.8%	1,559,805	-3.1%	3.14%	-7.0%
ESPR	Buy	ESPERION THERAPEUTICS INC NEW	$203,160,000	-25.3%	5,465,715	+3.1%	2.81%	-27.1%
ALXN	Buy	ALEXION PHARMACEUTICALS INC	$162,619,000	+2.5%	1,421,128	+0.6%	2.25%	+0.1%
MYOK	Sell	MYOKARDIA INC	$153,835,000	+31.8%	1,128,400	-6.6%	2.13%	+28.7%
AGIO	Buy	AGIOS PHARMACEUTICALS INC	$145,286,000	-32.5%	4,151,002	+3.2%	2.01%	-34.1%
HALO	Sell	HALOZYME THERAPEUTICS INC	$143,729,000	-20.3%	5,469,131	-18.7%	1.99%	-22.2%
ABT	Buy	ABBOTT LABS	$140,204,000	+19.4%	1,288,285	+0.3%	1.94%	+16.5%
MGNX	Buy	MACROGENICS INC	$133,059,000	-4.7%	5,282,188	+5.6%	1.84%	-7.0%
ISRG	Sell	INTUITIVE SURGICAL INC	$108,690,000	+22.1%	153,184	-2.0%	1.50%	+19.2%
UNH	Buy	UNITEDHEALTH GROUP INC	$101,030,000	+11.7%	324,053	+5.7%	1.40%	+9.1%
HUM	Buy	HUMANA INC	$100,987,000	+10.5%	243,996	+3.5%	1.40%	+7.9%
BMY	Buy	BRISTOL MYERS SQUIBB CO	$99,232,000	+4.7%	1,645,912	+2.1%	1.37%	+2.2%
DHR	Buy	DANAHER CORPORATION	$97,627,000	+22.2%	453,384	+0.4%	1.35%	+19.4%
SAGE	Buy	SAGE THERAPEUTICS INC	$96,539,000	+64.0%	1,579,504	+11.6%	1.33%	+60.1%
ANTM	Buy	ANTHEM INC	$93,771,000	+15.0%	349,123	+12.6%	1.30%	+12.3%
ITCI	Sell	INTRA CELLULAR THERAPIES INC	$91,861,000	-5.3%	3,579,919	-5.3%	1.27%	-7.6%
FATE	Buy	FATE THERAPEUTICS INC	$88,634,000	+31.7%	2,217,500	+13.1%	1.22%	+28.7%
MDT	Sell	MEDTRONIC PLC	$86,404,000	-3.6%	831,450	-14.9%	1.19%	-5.9%
RDUS	Buy	RADIUS HEALTH INC	$84,272,000	-11.8%	7,431,414	+6.1%	1.16%	-13.9%
CRL	Sell	CHARLES RIV LABS INTL INC	$79,502,000	+24.6%	351,083	-4.0%	1.10%	+21.6%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$79,396,000	+35.0%	949,262	+18.6%	1.10%	+31.7%
EXEL	Buy	EXELIXIS INC	$75,147,000	+3.9%	3,073,500	+0.9%	1.04%	+1.4%
BSX	Buy	BOSTON SCIENTIFIC CORP	$72,075,000	+18.6%	1,886,297	+9.0%	1.00%	+15.8%
MYOV	Buy	MYOVANT SCIENCES LTD	$71,542,000	-25.3%	5,092,000	+9.6%	0.99%	-27.1%
SYK	Sell	STRYKER CORPORATION	$67,256,000	+15.2%	322,771	-0.4%	0.93%	+12.5%
EW	Buy	EDWARDS LIFESCIENCES CORP	$66,076,000	+20.8%	827,818	+4.6%	0.91%	+18.0%
PODD	Buy	INSULET CORP	$63,850,000	+41.8%	269,875	+16.5%	0.88%	+38.5%
BDX	Buy	BECTON DICKINSON & CO	$60,694,000	+3.1%	260,846	+6.1%	0.84%	+0.7%
CNC	Sell	CENTENE CORP DEL	$60,293,000	-9.0%	1,033,647	-0.9%	0.83%	-11.2%
NKTR	Buy	NEKTAR THERAPEUTICS	$60,261,000	-26.4%	3,632,358	+2.8%	0.83%	-28.1%
GBIO	Buy	GENERATION BIO CO	$58,111,000	+92.2%	1,880,000	+30.6%	0.80%	+87.6%
CI	Sell	CIGNA CORP NEW	$56,877,000	-10.0%	335,737	-0.3%	0.79%	-12.1%
RLAY	New	RELAY THERAPEUTICS INC	$55,367,000	–	1,300,000	–	0.76%	–
MTEM	Buy	MOLECULAR TEMPLATES INC	$54,840,000	+14.4%	5,021,996	+44.4%	0.76%	+11.6%
GWPH	Buy	GW PHARMACEUTICALS PLCads	$54,803,000	+27.7%	562,943	+61.0%	0.76%	+24.7%
JAZZ	Buy	JAZZ PHARMACEUTICALS PLC	$50,812,000	+58.2%	356,350	+22.4%	0.70%	+54.3%
SRRK	Buy	SCHOLAR ROCK HLDG CORP	$50,284,000	+0.6%	2,842,515	+3.5%	0.70%	-1.8%
DXCM	Buy	DEXCOM INC	$50,170,000	+20.5%	121,705	+18.5%	0.69%	+17.7%
HRC	Buy	HILL ROM HLDGS INC	$47,690,000	+3.1%	571,069	+35.6%	0.66%	+0.6%
HOLX	Buy	HOLOGIC INC	$46,328,000	+53.0%	696,980	+31.2%	0.64%	+49.5%
AMGN	Buy	AMGEN INC	$45,651,000	+15.2%	179,613	+6.9%	0.63%	+12.5%
HCA	Buy	HCA HEALTHCARE INC	$43,025,000	+29.2%	345,085	+0.6%	0.59%	+26.1%
CDNA	Sell	CAREDX INC	$42,337,000	+2.4%	1,115,903	-4.4%	0.58%	0.0%
EVH	Sell	EVOLENT HEALTH INCcl a	$40,622,000	+13.5%	3,273,325	-34.9%	0.56%	+10.7%
BIO	Sell	BIO RAD LABS INCcl a	$40,302,000	+11.8%	78,186	-2.1%	0.56%	+9.2%
INSM	Sell	INSMED INC	$39,216,000	-2.2%	1,220,169	-16.2%	0.54%	-4.6%
ARVN	Buy	ARVINAS INC	$38,756,000	-26.9%	1,641,503	+3.8%	0.54%	-28.8%
PACB	Sell	PACIFIC BIOSIENCES CALIF IN	$38,537,000	+33.6%	3,904,467	-53.3%	0.53%	+30.4%
BAX	Sell	BAXTER INTL INC	$38,169,000	-29.1%	474,623	-24.1%	0.53%	-30.8%
TNDM	Buy	TANDEM DIABETES CARE INC	$35,576,000	+55.1%	313,444	+35.2%	0.49%	+51.4%
INSP	Buy	INSPIRE MED SYS INC	$35,228,000	+65.7%	272,983	+11.8%	0.49%	+61.8%
SWAV	Buy	SHOCKWAVE MED INC	$34,963,000	+76.5%	461,253	+10.3%	0.48%	+72.5%
AXNX	Buy	AXONICS MODULATION TECHNOLOG	$32,918,000	+81.5%	644,944	+24.9%	0.46%	+77.0%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$31,288,000	+24.3%	70,865	+2.0%	0.43%	+21.3%
EXAS	New	EXACT SCIENCES CORP	$31,043,000	–	304,490	–	0.43%	–
IDXX	Buy	IDEXX LABS INC	$30,819,000	+26.8%	78,398	+6.5%	0.43%	+23.8%
ZBH	Sell	ZIMMER BIOMET HOLDINGS INC	$30,732,000	+13.2%	225,740	-0.8%	0.42%	+10.7%
LVGO	Sell	LIVONGO HEALTH INC	$28,476,000	+47.2%	203,329	-21.0%	0.39%	+43.4%
ABMD	Buy	ABIOMED INC	$28,093,000	+20.3%	101,398	+4.9%	0.39%	+17.2%
DVA	Buy	DAVITA INC	$27,956,000	+17.7%	326,400	+8.7%	0.39%	+14.9%
ALGN	Sell	ALIGN TECHNOLOGY INC	$27,706,000	+2.1%	84,635	-14.4%	0.38%	-0.3%
VEEV	Buy	VEEVA SYS INC	$26,816,000	+81.4%	95,367	+51.2%	0.37%	+77.5%
TFX	Buy	TELEFLEX INCORPORATED	$26,772,000	-6.1%	78,644	+0.4%	0.37%	-8.4%
TDOC	Sell	TELADOC HEALTH INC	$26,606,000	-7.9%	121,354	-19.8%	0.37%	-10.0%
CHRS	Buy	COHERUS BIOSCIENCES INC	$25,738,000	+24.5%	1,403,400	+21.3%	0.36%	+21.5%
GKOS	Buy	GLAUKOS CORP	$25,540,000	+34.6%	515,754	+4.4%	0.35%	+31.2%
CHNG	Buy	CHANGE HEALTHCARE INC	$24,637,000	+51.2%	1,697,939	+16.7%	0.34%	+47.2%
QTRX	Buy	QUANTERIX CORP	$24,417,000	+86.7%	723,674	+51.6%	0.34%	+82.2%
MASI	Buy	MASIMO CORP	$24,114,000	+8.4%	102,153	+4.7%	0.33%	+5.7%
PEN	Buy	PENUMBRA INC	$23,558,000	+34.2%	121,194	+23.5%	0.33%	+31.5%
HMSY	Buy	HMS HLDGS CORP	$21,962,000	-16.7%	916,984	+12.6%	0.30%	-18.8%
KZR	Buy	KEZAR LIFE SCIENCES INC	$21,940,000	-0.2%	4,533,148	+6.9%	0.30%	-2.6%
IRTC	Sell	IRHYTHM TECHNOLOGIES INC	$21,553,000	+99.7%	90,518	-2.8%	0.30%	+94.8%
OMCL	Buy	OMNICELL INC	$20,787,000	+45.6%	278,421	+37.7%	0.29%	+42.1%
GMED	Buy	GLOBUS MED INCcl a	$20,290,000	+22.3%	409,735	+17.8%	0.28%	+19.1%
SILK	Buy	SILK RD MED INC	$20,205,000	+96.6%	300,619	+22.5%	0.28%	+92.4%
TXG	Buy	10X GENOMICS INC	$19,199,000	+74.7%	153,989	+25.1%	0.26%	+69.9%
HCAT	Buy	HEALTH CATALYST INC	$19,101,000	+87.5%	521,896	+49.5%	0.26%	+83.3%
GH	Buy	GUARDANT HEALTH INC	$18,151,000	+76.8%	162,383	+28.3%	0.25%	+73.1%
ILMN	Sell	ILLUMINA INC	$18,096,000	-49.1%	58,547	-39.0%	0.25%	-50.3%
GNMK	Sell	GENMARK DIAGNOSTICS INC	$17,946,000	-18.1%	1,263,811	-15.1%	0.25%	-20.0%
NVRO	Buy	NEVRO CORP	$16,795,000	+25.8%	120,569	+7.9%	0.23%	+22.8%
NEO	Sell	NEOGENOMICS INC	$15,748,000	+4.7%	426,892	-12.1%	0.22%	+2.3%
AMED	Buy	AMEDISYS INC	$14,623,000	+20.5%	61,851	+1.2%	0.20%	+17.4%
PHR	Buy	PHREESIA INC	$13,718,000	+28.6%	426,956	+13.2%	0.19%	+25.8%
ZLAB	Sell	ZAI LAB LTDadr	$13,407,000	-6.8%	161,200	-7.9%	0.18%	-9.3%
ONEM	Buy	1LIFE HEALTHCARE INC	$13,288,000	-18.1%	468,564	+4.9%	0.18%	-20.0%
AMWL	New	AMERICAN WELL CORPcl a	$11,259,000	–	379,854	–	0.16%	–
BGNE	Sell	BEIGENE LTDsponsored adr	$11,286,000	+3.3%	39,400	-32.1%	0.16%	+0.6%
REGN	Sell	REGENERON PHARMACEUTICALS	$11,196,000	-22.3%	20,000	-13.4%	0.16%	-24.0%
CVS	Sell	CVS HEALTH CORP	$10,920,000	-27.5%	186,981	-19.3%	0.15%	-29.1%
TRHC	Buy	TABULA RASA HEALTHCARE INC	$9,967,000	-15.9%	244,469	+12.9%	0.14%	-17.9%
OXFD	Buy	OXFORD IMMUNOTEC GLOBAL PLC	$9,362,000	+5.3%	800,157	+17.0%	0.13%	+2.4%
SGEN	Sell	SEATTLE GENETICS INC	$9,119,000	-2.3%	46,600	-15.1%	0.13%	-4.5%
BLI	New	BERKELEY LTS INC	$8,209,000	–	107,510	–	0.11%	–
ACCD	New	ACCOLADE INC	$8,137,000	–	209,327	–	0.11%	–
TMDX	Buy	TRANSMEDICS GROUP INC	$7,953,000	+4.4%	577,147	+35.8%	0.11%	+1.9%
GILD	Sell	GILEAD SCIENCES INC	$7,817,000	-24.5%	123,700	-8.0%	0.11%	-26.0%
XENT	Sell	INTERSECT ENT INC	$7,721,000	+1.3%	473,382	-15.9%	0.11%	-0.9%
AVTR	Sell	AVANTOR INC	$6,906,000	+11.3%	307,089	-15.8%	0.10%	+8.0%
AKCA	Sell	AKCEA THERAPEUTICS INC	$6,172,000	-69.2%	340,264	-76.7%	0.08%	-70.1%
HZNP	Sell	HORIZON THERAPEUTICS PUB LTD	$6,012,000	-31.6%	77,400	-51.1%	0.08%	-33.1%
VCRA	Sell	VOCERA COMMUNICATONS INC	$5,856,000	-19.7%	201,390	-41.5%	0.08%	-21.4%
IART	Sell	INTEGRA LIFESCIENCES HLDGS C	$5,781,000	-38.8%	122,426	-39.1%	0.08%	-40.3%
QTNT	Buy	QUOTIENT LTD	$4,714,000	+6.3%	917,074	+53.1%	0.06%	+3.2%
GOCO	New	GOHEALTH INC	$4,099,000	–	314,672	–	0.06%	–
NUVA	Buy	NUVASIVE INC	$3,988,000	+7.8%	82,100	+23.5%	0.06%	+5.8%
OM	New	OUTSET MED INC	$3,996,000	–	79,921	–	0.06%	–
BNR	Buy	BURNING ROCK BIOTECH LTDsponsored adr	$3,681,000	+203.0%	146,761	+226.1%	0.05%	+200.0%
RARE	Buy	ULTRAGENYX PHARMACEUTICAL IN	$3,370,000	+79.5%	41,000	+70.8%	0.05%	+74.1%
BNTX	Sell	BIONTECH SEsponsored ads	$3,427,000	+2.7%	49,500	-1.0%	0.05%	0.0%
IMAB	New	I MABsponsored ads	$3,057,000	–	65,000	–	0.04%	–
PFE	New	PFIZER INC	$2,712,000	–	73,900	–	0.04%	–
BIIB	New	BIOGEN INC	$2,440,000	–	8,600	–	0.03%	–
ASND	Buy	ASCENDIS PHARMA A Ssponsored adr	$2,392,000	+21.6%	15,500	+16.5%	0.03%	+17.9%
CVAC	New	CUREVAC NV	$2,351,000	–	50,500	–	0.03%	–
FGEN	New	FIBROGEN INC	$2,179,000	–	53,000	–	0.03%	–
GTH	Buy	GENETRON HLDGS LTDads	$1,915,000	+58.7%	160,410	+60.4%	0.03%	+52.9%
BHVN	New	BIOHAVEN PHARMACTL HLDG CO L	$1,593,000	–	24,500	–	0.02%	–
KURA	New	KURA ONCOLOGY INC	$1,471,000	–	48,000	–	0.02%	–
RDY	Sell	DR REDDYS LABS LTDadr	$591,000	-69.9%	8,500	-77.0%	0.01%	-71.4%
MTCH	New	MATCH GROUP INC NEW	$606,000	–	5,478	–	0.01%	–
STNE	New	STONECO LTD	$566,000	–	10,700	–	0.01%	–
CYBR	New	CYBERARK SOFTWARE LTD	$445,000	–	4,300	–	0.01%	–
ULTA	New	ULTA BEAUTY INC	$448,000	–	2,000	–	0.01%	–
IT	New	GARTNER INC	$425,000	–	3,400	–	0.01%	–
KOS	Buy	KOSMOS ENERGY LTD	$417,000	+317.0%	425,000	+608.3%	0.01%	+500.0%
AVNT	New	AVIENT CORPORATION	$360,000	–	13,600	–	0.01%	–
POL	Exit	POLYONE CORP	$0	–	-13,600	–	-0.01%	–
STIM	Exit	NEURONETICS INC	$0	–	-250,000	–	-0.01%	–
MTCH	Exit	MATCH GROUP INC	$0	–	-5,300	–	-0.01%	–
NARI	Exit	INARI MED INC	$0	–	-15,000	–	-0.01%	–
YI	Exit	111 INCads	$0	–	-170,525	–	-0.02%	–
RGNX	Exit	REGENXBIO INC	$0	–	-41,000	–	-0.02%	–
VIR	Exit	VIR BIOTECHNOLOGY INC	$0	–	-42,500	–	-0.02%	–
MNTA	Exit	MOMENTA PHARMACEUTICALS INC	$0	–	-74,400	–	-0.04%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-56,800	–	-0.04%	–
LEGN	Exit	LEGEND BIOTECH CORPsponsored ads	$0	–	-134,261	–	-0.08%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-76,900	–	-0.13%	–

Q2 2020

			Value		Shares		↓ Weighting
IONS	New	IONIS PHARMACEUTICALS INC	$486,413,000	–	8,249,873	–	6.88%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$391,730,000	–	3,210,900	–	5.54%	–
INCY	New	INCYTE CORP	$342,331,000	–	3,292,600	–	4.84%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$285,258,000	–	982,600	–	4.04%	–
ESPR	New	ESPERION THERAPEUTICS INC NEW	$272,104,000	–	5,303,135	–	3.85%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$238,467,000	–	1,610,065	–	3.38%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$215,181,000	–	4,023,573	–	3.04%	–
ARGX	New	ARGENX SEsponsored adr	$214,873,000	–	954,016	–	3.04%	–
MRNA	New	MODERNA INC	$214,779,000	–	3,344,950	–	3.04%	–
HALO	New	HALOZYME THERAPEUTICS INC	$180,446,000	–	6,730,552	–	2.55%	–
ALXN	New	ALEXION PHARMACEUTICALS INC	$158,576,000	–	1,412,828	–	2.24%	–
MGNX	New	MACROGENICS INC	$139,659,000	–	5,002,116	–	1.98%	–
ABT	New	ABBOTT LABS	$117,421,000	–	1,284,272	–	1.66%	–
MYOK	New	MYOKARDIA INC	$116,747,000	–	1,208,313	–	1.65%	–
ITCI	New	INTRA CELLULAR THERAPIES INC	$97,031,000	–	3,779,919	–	1.37%	–
MYOV	New	MYOVANT SCIENCES LTD	$95,821,000	–	4,647,000	–	1.36%	–
RDUS	New	RADIUS HEALTH INC	$95,511,000	–	7,007,385	–	1.35%	–
BMY	New	BRISTOL MYERS SQUIBB CO	$94,792,000	–	1,612,112	–	1.34%	–
HUM	New	HUMANA INC	$91,369,000	–	235,640	–	1.29%	–
UNH	New	UNITEDHEALTH GROUP INC	$90,442,000	–	306,636	–	1.28%	–
MDT	New	MEDTRONIC PLC	$89,639,000	–	977,523	–	1.27%	–
ISRG	New	INTUITIVE SURGICAL INC	$89,026,000	–	156,233	–	1.26%	–
NKTR	New	NEKTAR THERAPEUTICS	$81,871,000	–	3,535,013	–	1.16%	–
ANTM	New	ANTHEM INC	$81,530,000	–	310,025	–	1.15%	–
DHR	New	DANAHER CORPORATION	$79,862,000	–	451,633	–	1.13%	–
EXEL	New	EXELIXIS INC	$72,348,000	–	3,047,500	–	1.02%	–
FATE	New	FATE THERAPEUTICS INC	$67,295,000	–	1,961,400	–	0.95%	–
CNC	New	CENTENE CORP DEL	$66,267,000	–	1,042,747	–	0.94%	–
CRL	New	CHARLES RIV LABS INTL INC	$63,783,000	–	365,833	–	0.90%	–
CI	New	CIGNA CORP NEW	$63,187,000	–	336,726	–	0.89%	–
BSX	New	BOSTON SCIENTIFIC CORP	$60,762,000	–	1,730,620	–	0.86%	–
BDTX	New	BLACK DIAMOND THERAPEUTICS I	$59,150,000	–	1,403,000	–	0.84%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$58,826,000	–	800,462	–	0.83%	–
SAGE	New	SAGE THERAPEUTICS INC	$58,856,000	–	1,415,504	–	0.83%	–
BDX	New	BECTON DICKINSON & CO	$58,846,000	–	245,940	–	0.83%	–
SYK	New	STRYKER CORP	$58,371,000	–	323,942	–	0.83%	–
EW	New	EDWARDS LIFESCIENCES CORP	$54,713,000	–	791,682	–	0.77%	–
BAX	New	BAXTER INTL INC	$53,855,000	–	625,495	–	0.76%	–
ARVN	New	ARVINAS INC	$53,051,000	–	1,581,703	–	0.75%	–
SRRK	New	SCHOLAR ROCK HLDG CORP	$50,007,000	–	2,746,106	–	0.71%	–
MTEM	New	MOLECULAR TEMPLATES INC	$47,951,000	–	3,477,240	–	0.68%	–
HRC	New	HILL ROM HLDGS INC	$46,250,000	–	421,294	–	0.66%	–
PODD	New	INSULET CORP	$45,020,000	–	231,749	–	0.64%	–
GWPH	New	GW PHARMACEUTICALS PLCads	$42,899,000	–	349,566	–	0.61%	–
DXCM	New	DEXCOM INC	$41,637,000	–	102,705	–	0.59%	–
CDNA	New	CAREDX INC	$41,341,000	–	1,166,839	–	0.58%	–
INSM	New	INSMED INC	$40,103,000	–	1,456,174	–	0.57%	–
AMGN	New	AMGEN INC	$39,616,000	–	167,963	–	0.56%	–
BIO	New	BIO RAD LABS INCcl a	$36,061,000	–	79,871	–	0.51%	–
EVH	New	EVOLENT HEALTH INCcl a	$35,802,000	–	5,028,363	–	0.51%	–
ILMN	New	ILLUMINA INC	$35,571,000	–	96,047	–	0.50%	–
SGMO	New	SANGAMO THERAPEUTICS INC	$34,496,000	–	3,850,000	–	0.49%	–
VYGR	New	VOYAGER THERAPEUTICS INC	$34,226,000	–	2,712,083	–	0.48%	–
ICPT	New	INTERCEPT PHARMACEUTICALS IN	$33,775,000	–	704,976	–	0.48%	–
HCA	New	HCA HEALTHCARE INC	$33,308,000	–	343,166	–	0.47%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$32,124,000	–	291,136	–	0.46%	–
HOLX	New	HOLOGIC INC	$30,272,000	–	531,089	–	0.43%	–
GBIO	New	GENERATION BIO CO	$30,240,000	–	1,440,000	–	0.43%	–
MOH	New	MOLINA HEALTHCARE INC	$29,291,000	–	164,572	–	0.42%	–
TDOC	New	TELADOC HEALTH INC	$28,874,000	–	151,299	–	0.41%	–
PACB	New	PACIFIC BIOSIENCES CALIF IN	$28,855,000	–	8,363,741	–	0.41%	–
TFX	New	TELEFLEX INCORPORATED	$28,512,000	–	78,333	–	0.40%	–
ZBH	New	ZIMMER BIOMET HOLDINGS INC	$27,155,000	–	227,508	–	0.38%	–
ALGN	New	ALIGN TECHNOLOGY INC	$27,134,000	–	98,869	–	0.38%	–
WVE	New	WAVE LIFE SCIENCES LTD	$27,096,000	–	2,602,858	–	0.38%	–
HMSY	New	HMS HLDGS CORP	$26,374,000	–	814,264	–	0.37%	–
FIXX	New	HOMOLOGY MEDICINES INC	$26,387,000	–	1,737,122	–	0.37%	–
HCM	New	HUTCHISON CHINA MEDITECH LTDsponsored adr	$26,137,000	–	947,674	–	0.37%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$25,179,000	–	69,491	–	0.36%	–
IDXX	New	IDEXX LABS INC	$24,302,000	–	73,607	–	0.34%	–
DVA	New	DAVITA INC	$23,758,000	–	300,200	–	0.34%	–
ABMD	New	ABIOMED INC	$23,359,000	–	96,699	–	0.33%	–
TNDM	New	TANDEM DIABETES CARE INC	$22,934,000	–	231,839	–	0.32%	–
MASI	New	MASIMO CORP	$22,238,000	–	97,541	–	0.32%	–
KZR	New	KEZAR LIFE SCIENCES INC	$21,973,000	–	4,241,940	–	0.31%	–
GNMK	New	GENMARK DIAGNOSTICS INC	$21,907,000	–	1,489,284	–	0.31%	–
INSP	New	INSPIRE MED SYS INC	$21,255,000	–	244,250	–	0.30%	–
CHRS	New	COHERUS BIOSCIENCES INC	$20,671,000	–	1,157,400	–	0.29%	–
AKCA	New	AKCEA THERAPEUTICS INC	$20,033,000	–	1,462,296	–	0.28%	–
SWAV	New	SHOCKWAVE MED INC	$19,805,000	–	418,089	–	0.28%	–
LVGO	New	LIVONGO HEALTH INC	$19,343,000	–	257,258	–	0.27%	–
GKOS	New	GLAUKOS CORP	$18,972,000	–	493,811	–	0.27%	–
AXNX	New	AXONICS MODULATION TECHNOLOG	$18,132,000	–	516,428	–	0.26%	–
PEN	New	PENUMBRA INC	$17,552,000	–	98,152	–	0.25%	–
GTHX	New	G1 THERAPEUTICS INC	$17,514,000	–	721,925	–	0.25%	–
GMED	New	GLOBUS MED INCcl a	$16,590,000	–	347,729	–	0.24%	–
CHNG	New	CHANGE HEALTHCARE INC	$16,299,000	–	1,455,240	–	0.23%	–
ONEM	New	1LIFE HEALTHCARE INC	$16,228,000	–	446,807	–	0.23%	–
CVS	New	CVS HEALTH CORP	$15,052,000	–	231,681	–	0.21%	–
NEO	New	NEOGENOMICS INC	$15,040,000	–	485,470	–	0.21%	–
RMD	New	RESMED INC	$14,939,000	–	77,805	–	0.21%	–
VEEV	New	VEEVA SYS INC	$14,782,000	–	63,056	–	0.21%	–
ZLAB	New	ZAI LAB LTDadr	$14,381,000	–	175,100	–	0.20%	–
REGN	New	REGENERON PHARMACEUTICALS	$14,406,000	–	23,100	–	0.20%	–
OMCL	New	OMNICELL INC	$14,274,000	–	202,131	–	0.20%	–
NVRO	New	NEVRO CORP	$13,352,000	–	111,762	–	0.19%	–
QTRX	New	QUANTERIX CORP	$13,079,000	–	477,515	–	0.18%	–
AMED	New	AMEDISYS INC	$12,139,000	–	61,143	–	0.17%	–
TRHC	New	TABULA RASA HEALTHCARE INC	$11,853,000	–	216,581	–	0.17%	–
TXG	New	10X GENOMICS INC	$10,992,000	–	123,077	–	0.16%	–
BGNE	New	BEIGENE LTDsponsored adr	$10,927,000	–	58,000	–	0.16%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$10,794,000	–	93,140	–	0.15%	–
PHR	New	PHREESIA INC	$10,666,000	–	377,169	–	0.15%	–
CDTX	New	CIDARA THERAPEUTICS INC	$10,415,000	–	2,822,495	–	0.15%	–
GILD	New	GILEAD SCIENCES INC	$10,348,000	–	134,500	–	0.15%	–
GH	New	GUARDANT HEALTH INC	$10,268,000	–	126,561	–	0.14%	–
SILK	New	SILK RD MED INC	$10,277,000	–	245,338	–	0.14%	–
HCAT	New	HEALTH CATALYST INC	$10,185,000	–	349,169	–	0.14%	–
IART	New	INTEGRA LIFESCIENCES HLDGS C	$9,440,000	–	200,897	–	0.13%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$9,485,000	–	76,900	–	0.13%	–
SGEN	New	SEATTLE GENETICS INC	$9,329,000	–	54,900	–	0.13%	–
LH	New	LABORATORY CORP AMER HLDGS	$9,009,000	–	54,234	–	0.13%	–
OXFD	New	OXFORD IMMUNOTEC GLOBAL PLC	$8,889,000	–	683,795	–	0.13%	–
HZNP	New	HORIZON THERAPEUTICS PUB LTD	$8,793,000	–	158,200	–	0.12%	–
XENT	New	INTERSECT ENT INC	$7,624,000	–	563,090	–	0.11%	–
TMDX	New	TRANSMEDICS GROUP INC	$7,616,000	–	425,000	–	0.11%	–
VCRA	New	VOCERA COMMUNICATONS INC	$7,295,000	–	344,081	–	0.10%	–
COO	New	COOPER COS INC	$7,189,000	–	25,345	–	0.10%	–
XRAY	New	DENTSPLY SIRONA INC	$7,011,000	–	159,129	–	0.10%	–
DGX	New	QUEST DIAGNOSTICS INC	$6,838,000	–	60,005	–	0.10%	–
AVTR	New	AVANTOR INC	$6,203,000	–	364,877	–	0.09%	–
LEGN	New	LEGEND BIOTECH CORPsponsored ads	$5,714,000	–	134,261	–	0.08%	–
INGN	New	INOGEN INC	$5,289,000	–	148,912	–	0.08%	–
QTNT	New	QUOTIENT LTD	$4,434,000	–	599,154	–	0.06%	–
NUVA	New	NUVASIVE INC	$3,701,000	–	66,500	–	0.05%	–
ABBV	New	ABBVIE INC	$3,633,000	–	37,000	–	0.05%	–
BNTX	New	BIONTECH SEsponsored ads	$3,337,000	–	50,000	–	0.05%	–
SRPT	New	SAREPTA THERAPEUTICS INC	$3,255,000	–	20,300	–	0.05%	–
PTCT	New	PTC THERAPEUTICS INC	$2,882,000	–	56,800	–	0.04%	–
BMYRT	New	BRISTOL MYERS SQUIBB COright 99/99/9999	$2,864,000	–	800,000	–	0.04%	–
SNY	New	SANOFIsponsored adr	$2,910,000	–	57,000	–	0.04%	–
MNTA	New	MOMENTA PHARMACEUTICALS INC	$2,475,000	–	74,400	–	0.04%	–
ACAD	New	ACADIA PHARMACEUTICALS INC	$2,176,000	–	44,900	–	0.03%	–
MRTX	New	MIRATI THERAPEUTICS INC	$2,032,000	–	17,800	–	0.03%	–
ASND	New	ASCENDIS PHARMA A Ssponsored adr	$1,967,000	–	13,300	–	0.03%	–
RDY	New	DR REDDYS LABS LTDadr	$1,961,000	–	37,000	–	0.03%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL IN	$1,877,000	–	24,000	–	0.03%	–
VIR	New	VIR BIOTECHNOLOGY INC	$1,741,000	–	42,500	–	0.02%	–
QURE	New	UNIQURE NV	$1,555,000	–	34,500	–	0.02%	–
RGNX	New	REGENXBIO INC	$1,510,000	–	41,000	–	0.02%	–
CLLS	New	CELLECTIS S Aspon ads	$1,486,000	–	83,500	–	0.02%	–
BNR	New	BURNING ROCK BIOTECH LTDsponsored adr	$1,215,000	–	45,000	–	0.02%	–
GTH	New	GENETRON HLDGS LTDads	$1,207,000	–	100,000	–	0.02%	–
YI	New	111 INCads	$1,083,000	–	170,525	–	0.02%	–
NARI	New	INARI MED INC	$727,000	–	15,000	–	0.01%	–
EA	New	ELECTRONIC ARTS INC	$617,000	–	4,670	–	0.01%	–
A	New	AGILENT TECHNOLOGIES INC	$548,000	–	6,200	–	0.01%	–
MCO	New	MOODYS CORP	$549,000	–	2,000	–	0.01%	–
FDS	New	FACTSET RESH SYS INC	$558,000	–	1,700	–	0.01%	–
MTCH	New	MATCH GROUP INC	$567,000	–	5,300	–	0.01%	–
POOL	New	POOL CORPORATION	$598,000	–	2,200	–	0.01%	–
MCK	New	MCKESSON CORP	$597,000	–	3,892	–	0.01%	–
SPGI	New	S&P GLOBAL INC	$560,000	–	1,700	–	0.01%	–
MTD	New	METTLER TOLEDO INTERNATIONAL	$564,000	–	700	–	0.01%	–
BFB	New	BROWN FORMAN CORPcl b	$484,000	–	7,600	–	0.01%	–
MKC	New	MCCORMICK & CO INC	$502,000	–	2,800	–	0.01%	–
MELI	New	MERCADOLIBRE INC	$493,000	–	500	–	0.01%	–
JD	New	JD.COM INCspon adr cl a	$524,000	–	8,700	–	0.01%	–
STIM	New	NEURONETICS INC	$483,000	–	250,000	–	0.01%	–
HTHT	New	HUAZHU GROUP LTDsponsored ads	$473,000	–	13,500	–	0.01%	–
GGG	New	GRACO INC	$466,000	–	9,700	–	0.01%	–
PKI	New	PERKINELMER INC	$471,000	–	4,800	–	0.01%	–
CSGP	New	COSTAR GROUP INC	$497,000	–	700	–	0.01%	–
SWKS	New	SKYWORKS SOLUTIONS INC	$473,000	–	3,700	–	0.01%	–
SQM	New	SOCIEDAD QUIMICA MINERA DE Cspon adr ser b	$474,000	–	18,200	–	0.01%	–
TRMB	New	TRIMBLE INC	$505,000	–	11,700	–	0.01%	–
TYL	New	TYLER TECHNOLOGIES INC	$529,000	–	1,525	–	0.01%	–
VAR	New	VARIAN MED SYS INC	$502,000	–	4,100	–	0.01%	–
WSO	New	WATSCO INC	$498,000	–	2,800	–	0.01%	–
ANSS	New	ANSYS INC	$526,000	–	1,802	–	0.01%	–
ADI	New	ANALOG DEVICES INC	$503,000	–	4,100	–	0.01%	–
ADBE	New	ADOBE INC	$479,000	–	1,100	–	0.01%	–
CTLT	New	CATALENT INC	$418,000	–	5,700	–	0.01%	–
PAYX	New	PAYCHEX INC	$409,000	–	5,400	–	0.01%	–
TRU	New	TRANSUNION	$444,000	–	5,096	–	0.01%	–
MKTX	New	MARKETAXESS HLDGS INC	$412,000	–	822	–	0.01%	–
FTNT	New	FORTINET INC	$398,000	–	2,900	–	0.01%	–
IPGP	New	IPG PHOTONICS CORP	$433,000	–	2,700	–	0.01%	–
VRSN	New	VERISIGN INC	$434,000	–	2,100	–	0.01%	–
VRSK	New	VERISK ANALYTICS INC	$424,000	–	2,489	–	0.01%	–
IBKR	New	INTERACTIVE BROKERS GROUP IN	$393,000	–	9,400	–	0.01%	–
ICE	New	INTERCONTINENTAL EXCHANGE IN	$440,000	–	4,800	–	0.01%	–
IQV	New	IQVIA HLDGS INC	$411,000	–	2,900	–	0.01%	–
ALV	New	AUTOLIV INC	$439,000	–	6,800	–	0.01%	–
XLNX	New	XILINX INC	$413,000	–	4,200	–	0.01%	–
EL	New	LAUDER ESTEE COS INCcl a	$424,000	–	2,248	–	0.01%	–
CLX	New	CLOROX CO DEL	$439,000	–	2,000	–	0.01%	–
MSCI	New	MSCI INC	$396,000	–	1,186	–	0.01%	–
ENTG	New	ENTEGRIS INC	$431,000	–	7,300	–	0.01%	–
BR	New	BROADRIDGE FINL SOLUTIONS IN	$429,000	–	3,400	–	0.01%	–
FAST	New	FASTENAL CO	$428,000	–	10,000	–	0.01%	–
TW	New	TRADEWEB MKTS INCcl a	$395,000	–	6,800	–	0.01%	–
AXP	New	AMERICAN EXPRESS CO	$343,000	–	3,600	–	0.01%	–
ST	New	SENSATA TECHNOLOGIES HLDNG P	$369,000	–	9,900	–	0.01%	–
TCOM	New	TRIP COM GROUP LTDads	$340,000	–	13,100	–	0.01%	–
DPZ	New	DOMINOS PIZZA INC	$369,000	–	1,000	–	0.01%	–
MKL	New	MARKEL CORP	$369,000	–	400	–	0.01%	–
POL	New	POLYONE CORP	$357,000	–	13,600	–	0.01%	–
SCI	New	SERVICE CORP INTL	$331,000	–	8,500	–	0.01%	–
BKNG	New	BOOKING HLDGS INC	$318,000	–	200	–	0.01%	–
STZ	New	CONSTELLATION BRANDS INCcl a	$360,000	–	2,059	–	0.01%	–
SBUX	New	STARBUCKS CORP	$319,000	–	4,334	–	0.01%	–
WAB	New	WABTEC	$368,000	–	6,400	–	0.01%	–
AZPN	New	ASPEN TECHNOLOGY INC	$311,000	–	3,000	–	0.00%	–
LYV	New	LIVE NATION ENTERTAINMENT IN	$275,000	–	6,200	–	0.00%	–
BLKB	New	BLACKBAUD INC	$234,000	–	4,107	–	0.00%	–
KOS	New	KOSMOS ENERGY LTD	$100,000	–	60,000	–	0.00%	–
CVET	New	COVETRUS INC	$27,000	–	1,520	–	0.00%	–

Q4 2019

			Value		Shares		↓ Weighting
CVET	Exit	COVETRUS INC	$0	–	-1,520	–	0.00%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INCcall	$0	–	-150	–	-0.00%	–
STML	Exit	STEMLINE THERAPEUTICS INC	$0	–	-31,500	–	-0.01%	–
AZPN	Exit	ASPEN TECHNOLOGY INC	$0	–	-3,000	–	-0.01%	–
CTRP	Exit	CTRIP COM INTL LTDsponsored ads	$0	–	-13,100	–	-0.01%	–
SBUX	Exit	STARBUCKS CORP	$0	–	-4,334	–	-0.01%	–
LIN	Exit	LINDE PLC	$0	–	-1,848	–	-0.01%	–
XLNX	Exit	XILINX INC	$0	–	-4,200	–	-0.01%	–
VRSN	Exit	VERISIGN INC	$0	–	-2,100	–	-0.01%	–
TYL	Exit	TYLER TECHNOLOGIES INC	$0	–	-1,525	–	-0.01%	–
BKNG	Exit	BOOKING HLDGS INC	$0	–	-200	–	-0.01%	–
MSCI	Exit	MSCI INC	$0	–	-1,786	–	-0.01%	–
ANSS	Exit	ANSYS INC	$0	–	-1,802	–	-0.01%	–
KOS	Exit	KOSMOS ENERGY LTD	$0	–	-60,000	–	-0.01%	–
BLKB	Exit	BLACKBAUD INC	$0	–	-4,107	–	-0.01%	–
VRSK	Exit	VERISK ANALYTICS INC	$0	–	-2,489	–	-0.01%	–
MCO	Exit	MOODYS CORP	$0	–	-2,000	–	-0.01%	–
AXP	Exit	AMERICAN EXPRESS CO	$0	–	-3,600	–	-0.01%	–
SPGI	Exit	S&P GLOBAL INC	$0	–	-1,700	–	-0.01%	–
LYV	Exit	LIVE NATION ENTERTAINMENT IN	$0	–	-6,200	–	-0.01%	–
ADBE	Exit	ADOBE INC	$0	–	-1,500	–	-0.01%	–
VNE	Exit	VEONEER INCORPORATED	$0	–	-29,700	–	-0.01%	–
EL	Exit	LAUDER ESTEE COS INCcl a	$0	–	-2,248	–	-0.01%	–
CLX	Exit	CLOROX CO DEL	$0	–	-2,800	–	-0.01%	–
ICE	Exit	INTERCONTINENTAL EXCHANGE IN	$0	–	-4,800	–	-0.01%	–
TRMB	Exit	TRIMBLE INC	$0	–	-11,700	–	-0.01%	–
PAYX	Exit	PAYCHEX INC	$0	–	-5,400	–	-0.01%	–
POL	Exit	POLYONE CORP	$0	–	-13,600	–	-0.01%	–
CERN	Exit	CERNER CORP	$0	–	-6,200	–	-0.01%	–
BR	Exit	BROADRIDGE FINL SOLUTIONS IN	$0	–	-3,400	–	-0.01%	–
MKTX	Exit	MARKETAXESS HLDGS INC	$0	–	-1,322	–	-0.01%	–
POOL	Exit	POOL CORPORATION	$0	–	-2,200	–	-0.01%	–
JD	Exit	JD COM INCspon adr cl a	$0	–	-14,700	–	-0.01%	–
GGG	Exit	GRACO INC	$0	–	-9,700	–	-0.01%	–
MKC	Exit	MCCORMICK & CO INC	$0	–	-2,800	–	-0.01%	–
HTHT	Exit	HUAZHU GROUP LTDsponsored ads	$0	–	-13,500	–	-0.01%	–
SWKS	Exit	SKYWORKS SOLUTIONS INC	$0	–	-5,700	–	-0.01%	–
AUTL	Exit	AUTOLUS THERAPEUTICS PLCspon ads	$0	–	-34,600	–	-0.01%	–
CL	Exit	COLGATE PALMOLIVE CO	$0	–	-6,100	–	-0.01%	–
KEX	Exit	KIRBY CORP	$0	–	-5,900	–	-0.01%	–
VAR	Exit	VARIAN MED SYS INC	$0	–	-4,100	–	-0.01%	–
IBKR	Exit	INTERACTIVE BROKERS GROUP IN	$0	–	-9,400	–	-0.01%	–
MKL	Exit	MARKEL CORP	$0	–	-400	–	-0.01%	–
WSO	Exit	WATSCO INC	$0	–	-2,800	–	-0.01%	–
WAB	Exit	WABTEC CORP	$0	–	-6,400	–	-0.01%	–
ENTG	Exit	ENTEGRIS INC	$0	–	-10,300	–	-0.01%	–
MCHP	Exit	MICROCHIP TECHNOLOGY INC	$0	–	-5,000	–	-0.01%	–
IPGP	Exit	IPG PHOTONICS CORP	$0	–	-3,500	–	-0.01%	–
EA	Exit	ELECTRONIC ARTS INC	$0	–	-4,800	–	-0.01%	–
ADI	Exit	ANALOG DEVICES INC	$0	–	-4,100	–	-0.01%	–
MTD	Exit	METTLER TOLEDO INTERNATIONAL	$0	–	-700	–	-0.01%	–
DPZ	Exit	DOMINOS PIZZA INC	$0	–	-1,900	–	-0.01%	–
BFB	Exit	BROWN FORMAN CORPcl b	$0	–	-7,600	–	-0.01%	–
ST	Exit	SENSATA TECHNOLOGIES HLDNG P	$0	–	-9,900	–	-0.01%	–
SQM	Exit	SOCIEDAD QUIMICA MINERA DE Cspon adr ser b	$0	–	-18,200	–	-0.01%	–
MTB	Exit	M & T BK CORP	$0	–	-3,000	–	-0.01%	–
ALV	Exit	AUTOLIV INC	$0	–	-6,800	–	-0.01%	–
CBPO	Exit	CHINA BIOLOGIC PRODS HLDGS I	$0	–	-4,500	–	-0.01%	–
ADMS	Exit	ADAMAS PHARMACEUTICALS INC	$0	–	-116,000	–	-0.01%	–
FAST	Exit	FASTENAL CO	$0	–	-19,299	–	-0.01%	–
MNTA	Exit	MOMENTA PHARMACEUTICALS INC	$0	–	-50,000	–	-0.01%	–
LVGO	Exit	LIVONGO HEALTH INC	$0	–	-43,220	–	-0.01%	–
MCK	Exit	MCKESSON CORP	$0	–	-5,924	–	-0.02%	–
ZGNX	Exit	ZOGENIX INC	$0	–	-23,000	–	-0.02%	–
LH	Exit	LABORATORY CORP AMER HLDGS	$0	–	-5,573	–	-0.02%	–
FATE	Exit	FATE THERAPEUTICS INC	$0	–	-60,100	–	-0.02%	–
ZLAB	Exit	ZAI LAB LTDadr	$0	–	-30,000	–	-0.02%	–
XLRN	Exit	ACCELERON PHARMA INC	$0	–	-25,800	–	-0.02%	–
TEVA	Exit	TEVA PHARMACEUTICAL INDS LTDsponsored ads	$0	–	-150,000	–	-0.02%	–
CRL	Exit	CHARLES RIV LABS INTL INC	$0	–	-8,300	–	-0.02%	–
ARNA	Exit	ARENA PHARMACEUTICALS INC	$0	–	-23,517	–	-0.02%	–
PTLA	Exit	PORTOLA PHARMACEUTICALS INC	$0	–	-43,700	–	-0.02%	–
RGNX	Exit	REGENXBIO INC	$0	–	-33,700	–	-0.02%	–
BPMC	Exit	BLUEPRINT MEDICINES CORP	$0	–	-15,800	–	-0.02%	–
GWPH	Exit	GW PHARMACEUTICALS PLCads	$0	–	-10,453	–	-0.02%	–
QURE	Exit	UNIQURE NV	$0	–	-30,900	–	-0.02%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-15,900	–	-0.02%	–
ASND	Exit	ASCENDIS PHARMA A Ssponsored adr	$0	–	-13,600	–	-0.02%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-10,000	–	-0.02%	–
LABD	Exit	DIREXION SHS ETF TRdaily s&p biotec	$0	–	-55,000	–	-0.03%	–
PFE	Exit	PFIZER INC	$0	–	-40,000	–	-0.03%	–
MDCO	Exit	MEDICINES CO	$0	–	-28,900	–	-0.03%	–
CTLT	Exit	CATALENT INC	$0	–	-37,500	–	-0.03%	–
BNFT	Exit	BENEFITFOCUS INC	$0	–	-90,463	–	-0.04%	–
A	Exit	AGILENT TECHNOLOGIES INC	$0	–	-29,800	–	-0.04%	–
BIO	Exit	BIO RAD LABS INCcl a	$0	–	-6,750	–	-0.04%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-166,300	–	-0.05%	–
STIM	Exit	NEURONETICS INC	$0	–	-325,961	–	-0.05%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-81,200	–	-0.05%	–
AVTR	Exit	AVANTOR INC	$0	–	-196,951	–	-0.05%	–
SWAV	Exit	SHOCKWAVE MED INC	$0	–	-101,358	–	-0.06%	–
SYNH	Exit	SYNEOS HEALTH INCcl a	$0	–	-62,000	–	-0.06%	–
ACAD	Exit	ACADIA PHARMACEUTICALS INC	$0	–	-90,400	–	-0.06%	–
PEN	Exit	PENUMBRA INC	$0	–	-25,048	–	-0.06%	–
HSIC	Exit	HENRY SCHEIN INC	$0	–	-63,575	–	-0.08%	–
KZR	Exit	KEZAR LIFE SCIENCES INC	$0	–	-1,230,523	–	-0.08%	–
CHRS	Exit	COHERUS BIOSCIENCES INC	$0	–	-201,435	–	-0.08%	–
SILK	Exit	SILK RAOD MEDICAL INC	$0	–	-131,954	–	-0.08%	–
MTLS	Exit	MATERIALISE NVsponsored ads	$0	–	-240,770	–	-0.08%	–
CDTX	Exit	CIDARA THERAPEUTICS INC	$0	–	-2,295,272	–	-0.08%	–
SDC	Exit	SMILEDIRECTCLUB INC	$0	–	-350,000	–	-0.09%	–
TXG	Exit	10X GENOMICS INC	$0	–	-100,000	–	-0.09%	–
HCAT	Exit	HEALTH CATALYST INC	$0	–	-160,216	–	-0.09%	–
AGN	Exit	ALLERGAN PLC	$0	–	-30,800	–	-0.10%	–
PHR	Exit	PHREESIA INC	$0	–	-220,690	–	-0.10%	–
INGN	Exit	INOGEN INC	$0	–	-113,323	–	-0.10%	–
QTNT	Exit	QUOTIENT LTD	$0	–	-747,894	–	-0.11%	–
MYL	Exit	MYLAN N V	$0	–	-293,200	–	-0.11%	–
GH	Exit	GUARDANT HEALTH INC	$0	–	-94,761	–	-0.11%	–
VCRA	Exit	VOCERA COMMUNICATONS INC	$0	–	-249,173	–	-0.11%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-105,688	–	-0.12%	–
SGEN	Exit	SEATTLE GENETICS INC	$0	–	-81,300	–	-0.13%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-131,818	–	-0.13%	–
RMD	Exit	RESMED INC	$0	–	-54,630	–	-0.14%	–
BIIB	Exit	BIOGEN INC	$0	–	-32,350	–	-0.14%	–
VEEV	Exit	VEEVA SYS INC	$0	–	-50,884	–	-0.14%	–
XENT	Exit	INTERSECT ENT INC	$0	–	-458,588	–	-0.14%	–
HOLX	Exit	HOLOGIC INC	$0	–	-155,208	–	-0.15%	–
HZNP	Exit	HORIZON THERAPEUTICS PUB LTD	$0	–	-323,300	–	-0.16%	–
QTRX	Exit	QUANTERIX CORP	$0	–	-406,101	–	-0.17%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-72,100	–	-0.17%	–
IDXX	Exit	IDEXX LABS INC	$0	–	-34,134	–	-0.17%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-85,239	–	-0.17%	–
COO	Exit	COOPER COS INC	$0	–	-31,969	–	-0.18%	–
QDEL	Exit	QUIDEL CORP	$0	–	-160,016	–	-0.18%	–
FIT	Exit	FITBIT INCcl a	$0	–	-2,659,944	–	-0.19%	–
MASI	Exit	MASIMO CORP	$0	–	-68,392	–	-0.19%	–
CHNG	Exit	CHANGE HEALTHCARE INC	$0	–	-863,922	–	-0.19%	–
OXFD	Exit	OXFORD IMMUNOTEC GLOBAL PLC	$0	–	-637,972	–	-0.20%	–
TRHC	Exit	TABULA RASA HEALTHCARE INC	$0	–	-201,693	–	-0.21%	–
AMGN	Exit	AMGEN INC	$0	–	-57,700	–	-0.21%	–
SUPN	Exit	SUPERNUS PHARMACEUTICALS INC	$0	–	-416,600	–	-0.21%	–
TNDM	Exit	TANDEM DIABETES CARE INC	$0	–	-194,736	–	-0.21%	–
PACB	Exit	PACIFIC BIOSIENCES CALIF IN	$0	–	-2,373,787	–	-0.23%	–
OMCL	Exit	OMNICELL INC	$0	–	-171,646	–	-0.23%	–
NVRO	Exit	NEVRO CORP	$0	–	-145,111	–	-0.23%	–
IART	Exit	INTEGRA LIFESCIENCES HLDGS C	$0	–	-213,557	–	-0.24%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-184,419	–	-0.25%	–
HCM	Exit	HUTCHISON CHINA MEDITECH LTDsponsored adr	$0	–	-788,198	–	-0.26%	–
GNMK	Exit	GENMARK DIAGNOSTICS INC	$0	–	-2,267,252	–	-0.26%	–
HMSY	Exit	HMS HLDGS CORP	$0	–	-411,972	–	-0.26%	–
PODD	Exit	INSULET CORP	$0	–	-89,245	–	-0.27%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-243,457	–	-0.28%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-297,666	–	-0.28%	–
CDNA	Exit	CAREDX INC	$0	–	-722,655	–	-0.30%	–
GTHX	Exit	G1 THERAPEUTICS INC	$0	–	-721,925	–	-0.31%	–
WMGI	Exit	WRIGHT MED GROUP NV	$0	–	-804,291	–	-0.31%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-57,236	–	-0.31%	–
ARVN	Exit	ARVINAS INC	$0	–	-806,403	–	-0.32%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-2,588,990	–	-0.36%	–
SRRK	Exit	SCHOLAR ROCK HOLDING CORP	$0	–	-2,197,100	–	-0.37%	–
ZBH	Exit	ZIMMER BIOMET HLDGS INC	$0	–	-144,373	–	-0.37%	–
LIVN	Exit	LIVANOVA PLC	$0	–	-271,314	–	-0.37%	–
TFX	Exit	TELEFLEX INC	$0	–	-59,114	–	-0.37%	–
HRC	Exit	HILL ROM HLDGS INC	$0	–	-198,762	–	-0.39%	–
INSM	Exit	INSMED INC	$0	–	-1,191,480	–	-0.39%	–
QGEN	Exit	QIAGEN NV	$0	–	-638,943	–	-0.39%	–
EVH	Exit	EVOLENT HEALTH INCcl a	$0	–	-3,025,022	–	-0.40%	–
AMED	Exit	AMEDISYS INC	$0	–	-175,658	–	-0.43%	–
ABMD	Exit	ABIOMED INC	$0	–	-133,031	–	-0.44%	–
MYOV	Exit	MYOVANT SCIENCES LTD	$0	–	-4,815,109	–	-0.47%	–
GKOS	Exit	GLAUKOS CORP	$0	–	-402,148	–	-0.47%	–
DXCM	Exit	DEXCOM INC	$0	–	-168,887	–	-0.47%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-211,382	–	-0.47%	–
FIXX	Exit	HOMOLOGY MEDICINES INC	$0	–	-1,612,122	–	-0.54%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-692,914	–	-0.56%	–
BAX	Exit	BAXTER INTL INC	$0	–	-355,568	–	-0.58%	–
WVE	Exit	WAVE LIFE SCIENCES LTD	$0	–	-1,552,858	–	-0.59%	–
SGMO	Exit	SANGAMO THERAPEUTICS INC	$0	–	-3,650,000	–	-0.61%	–
CRSP	Exit	CRISPR THERAPEUTICS AGnamen akt	$0	–	-837,162	–	-0.64%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-551,600	–	-0.65%	–
CI	Exit	CIGNA CORP NEW	$0	–	-239,294	–	-0.68%	–
BOLD	Exit	AUDENTES THERAPEUTICS INC	$0	–	-1,429,604	–	-0.75%	–
SYK	Exit	STRYKER CORP	$0	–	-188,284	–	-0.76%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-330,227	–	-0.79%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-194,432	–	-0.80%	–
VYGR	Exit	VOYAGER THERAPEUTICS INC	$0	–	-2,704,683	–	-0.87%	–
ICPT	Exit	INTERCEPT PHARMACEUTICALS IN	$0	–	-702,176	–	-0.87%	–
BMY	Exit	BRISTOL MYERS SQUIBB CO	$0	–	-937,009	–	-0.88%	–
AKCA	Exit	AKCEA THERAPEUTICS INC	$0	–	-3,109,911	–	-0.89%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-200,827	–	-0.94%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-238,712	–	-0.96%	–
DHR	Exit	DANAHER CORPORATION	$0	–	-371,763	–	-1.00%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-1,419,988	–	-1.08%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-3,172,886	–	-1.08%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-338,483	–	-1.14%	–
HUM	Exit	HUMANA INC	$0	–	-242,673	–	-1.15%	–
ILMN	Exit	ILLUMINA INC	$0	–	-207,332	–	-1.17%	–
MGNX	Exit	MACROGENICS INC	$0	–	-5,125,564	–	-1.22%	–
MYOK	Exit	MYOKARDIA INC	$0	–	-1,292,513	–	-1.25%	–
EXEL	Exit	EXELIXIS INC	$0	–	-3,858,700	–	-1.27%	–
ANTM	Exit	ANTHEM INC	$0	–	-306,106	–	-1.37%	–
MRNA	Exit	MODERNA INC	$0	–	-4,844,081	–	-1.43%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-1,139,057	–	-1.44%	–
ALDR	Exit	ALDER BIOPHARMACEUTICALS INC	$0	–	-4,492,466	–	-1.58%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-807,638	–	-1.63%	–
ABT	Exit	ABBOTT LABS	$0	–	-1,098,114	–	-1.71%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-175,645	–	-1.76%	–
CELG	Exit	CELGENE CORP	$0	–	-1,085,600	–	-2.00%	–
ARGX	Exit	ARGENX SEsponsored adr	$0	–	-973,239	–	-2.05%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-3,571,554	–	-2.15%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-8,014,356	–	-2.31%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INC	$0	–	-1,366,528	–	-2.49%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NEW	$0	–	-4,241,461	–	-2.89%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-1,965,072	–	-2.94%	–
RDUS	Exit	RADIUS HEALTH INC	$0	–	-6,876,885	–	-3.29%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-1,303,504	–	-3.40%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-1,429,139	–	-4.50%	–
INCY	Exit	INCYTE CORP	$0	–	-3,696,200	–	-5.10%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-3,298,474	–	-5.53%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-8,321,914	–	-9.27%	–

Q3 2019

			Value		Shares		↓ Weighting
IONS	Buy	IONIS PHARMACEUTICALS INC	$498,566,000	-2.5%	8,321,914	+4.6%	9.27%	+6.2%
NBIX	Sell	NEUROCRINE BIOSCIENCES INC	$297,225,000	-0.7%	3,298,474	-7.0%	5.53%	+8.1%
INCY	Sell	INCYTE CORP	$274,369,000	-12.7%	3,696,200	-0.0%	5.10%	-4.9%
VRTX	Buy	VERTEX PHARMACEUTICALS INC	$242,125,000	-7.0%	1,429,139	+0.6%	4.50%	+1.2%
SAGE	Sell	SAGE THERAPEUTICS INC	$182,869,000	-24.4%	1,303,504	-1.4%	3.40%	-17.7%
RDUS	Buy	RADIUS HEALTH INC	$177,079,000	+6.3%	6,876,885	+0.5%	3.29%	+15.7%
ALNY	Buy	ALNYLAM PHARMACEUTICALS INC	$158,031,000	+13.0%	1,965,072	+2.0%	2.94%	+23.1%
ESPR	Buy	ESPERION THERAPEUTICS INC NEW	$155,492,000	-17.6%	4,241,461	+4.5%	2.89%	-10.3%
ALXN	Buy	ALEXION PHARMACEUTICALS INC	$133,838,000	-23.8%	1,366,528	+1.9%	2.49%	-17.0%
HALO	Sell	HALOZYME THERAPEUTICS INC	$124,303,000	-12.3%	8,014,356	-2.8%	2.31%	-4.4%
AGIO	Buy	AGIOS PHARMACEUTICALS INC	$115,718,000	-25.8%	3,571,554	+14.2%	2.15%	-19.2%
ARGX	Buy	ARGENX SEsponsored adr	$110,360,000	-17.5%	973,239	+3.0%	2.05%	-10.1%
CELG	Sell	CELGENE CORP	$107,801,000	-37.0%	1,085,600	-41.3%	2.00%	-31.3%
ISRG	Buy	INTUITIVE SURGICAL INC	$94,836,000	+7.3%	175,645	+4.3%	1.76%	+16.9%
ABT	Buy	ABBOTT LABS	$91,879,000	+14.1%	1,098,114	+14.7%	1.71%	+24.3%
MDT	Buy	MEDTRONIC PLC	$87,726,000	+15.6%	807,638	+3.6%	1.63%	+25.9%
ALDR	Buy	ALDER BIOPHARMACEUTICALS INC	$84,728,000	+74.8%	4,492,466	+9.1%	1.58%	+90.3%
TDOC	Sell	TELADOC HEALTH INC	$77,137,000	-19.1%	1,139,057	-20.6%	1.44%	-11.8%
MRNA	Buy	MODERNA INC	$77,118,000	+11.5%	4,844,081	+2.5%	1.43%	+21.4%
ANTM	Sell	ANTHEM INC	$73,496,000	-27.8%	306,106	-15.1%	1.37%	-21.3%
EXEL	Sell	EXELIXIS INC	$68,241,000	-17.7%	3,858,700	-0.5%	1.27%	-10.3%
MYOK	Buy	MYOKARDIA INC	$67,404,000	+6.3%	1,292,513	+2.2%	1.25%	+15.8%
MGNX	Buy	MACROGENICS INC	$65,402,000	-12.3%	5,125,564	+16.6%	1.22%	-4.6%
ILMN	Sell	ILLUMINA INC	$63,075,000	-24.9%	207,332	-9.1%	1.17%	-18.2%
HUM	Buy	HUMANA INC	$62,044,000	-3.0%	242,673	+0.6%	1.15%	+5.6%
ALGN	Buy	ALIGN TECHNOLOGY INC	$61,238,000	-27.0%	338,483	+10.4%	1.14%	-20.5%
BSX	Buy	BOSTON SCIENTIFIC CORP	$57,779,000	-2.6%	1,419,988	+2.8%	1.08%	+6.1%
NKTR	Buy	NEKTAR THERAPEUTICS	$57,794,000	-38.3%	3,172,886	+20.5%	1.08%	-32.8%
DHR	Buy	DANAHER CORPORATION	$53,694,000	+7.1%	371,763	+6.0%	1.00%	+16.7%
UNH	Buy	UNITEDHEALTH GROUP INC	$51,877,000	+9.4%	238,712	+22.8%	0.96%	+19.1%
BDX	Buy	BECTON DICKINSON & CO	$50,801,000	+34.7%	200,827	+34.2%	0.94%	+46.7%
AKCA	Buy	AKCEA THERAPEUTICS INC	$47,861,000	-34.2%	3,109,911	+0.3%	0.89%	-28.3%
BMY	Buy	BRISTOL MYERS SQUIBB CO	$47,516,000	+22.5%	937,009	+9.5%	0.88%	+33.3%
ICPT	Sell	INTERCEPT PHARMACEUTICALS IN	$46,596,000	-17.7%	702,176	-1.4%	0.87%	-10.3%
VYGR	Buy	VOYAGER THERAPEUTICS INC	$46,548,000	-36.2%	2,704,683	+0.9%	0.87%	-30.5%
EW	Buy	EDWARDS LIFESCIENCES CORP	$42,758,000	+33.0%	194,432	+11.8%	0.80%	+44.8%
JAZZ	Sell	JAZZ PHARMACEUTICALS PLC	$42,315,000	-10.6%	330,227	-0.6%	0.79%	-2.7%
SYK	Buy	STRYKER CORP	$40,726,000	+24.5%	188,284	+18.3%	0.76%	+35.4%
BOLD	Buy	AUDENTES THERAPEUTICS INC	$40,158,000	-22.6%	1,429,604	+4.4%	0.75%	-15.6%
CI	Buy	CIGNA CORP NEW	$36,322,000	+9.4%	239,294	+13.5%	0.68%	+19.2%
GILD	Sell	GILEAD SCIENCES INC	$34,960,000	-51.6%	551,600	-48.4%	0.65%	-47.3%
CRSP	Buy	CRISPR THERAPEUTICS AGnamen akt	$34,315,000	-10.1%	837,162	+3.3%	0.64%	-2.1%
WVE	Buy	WAVE LIFE SCIENCES LTD	$31,880,000	-19.3%	1,552,858	+2.5%	0.59%	-12.1%
BAX	Buy	BAXTER INTL INC	$31,102,000	+20.9%	355,568	+13.2%	0.58%	+31.7%
CNC	Buy	CENTENE CORP DEL	$29,975,000	-15.3%	692,914	+2.7%	0.56%	-7.8%
FIXX	Buy	HOMOLOGY MEDICINES INC	$29,179,000	+6.3%	1,612,122	+15.0%	0.54%	+15.8%
HCA	Buy	HCA HEALTHCARE INC	$25,455,000	+0.8%	211,382	+13.2%	0.47%	+9.7%
DXCM	Buy	DEXCOM INC	$25,205,000	+1.9%	168,887	+2.3%	0.47%	+11.1%
GKOS	Buy	GLAUKOS CORP	$25,138,000	+210.9%	402,148	+275.0%	0.47%	+239.1%
MYOV	Buy	MYOVANT SCIENCES LTD	$25,039,000	-29.2%	4,815,109	+23.1%	0.47%	-22.8%
ABMD	Sell	ABIOMED INC	$23,665,000	-32.5%	133,031	-1.2%	0.44%	-26.5%
AMED	Buy	AMEDISYS INC	$23,013,000	+8.7%	175,658	+0.8%	0.43%	+18.6%
EVH	Buy	EVOLENT HEALTH INCcl a	$21,750,000	+16.5%	3,025,022	+28.8%	0.40%	+27.0%
QGEN	Sell	QIAGEN NV	$21,066,000	-30.2%	638,943	-14.2%	0.39%	-23.9%
INSM	Buy	INSMED INC	$21,018,000	+32.3%	1,191,480	+92.0%	0.39%	+44.3%
HRC	Sell	HILL ROM HLDGS INC	$20,916,000	-14.3%	198,762	-14.8%	0.39%	-6.7%
TFX	Buy	TELEFLEX INC	$20,084,000	+65.0%	59,114	+60.8%	0.37%	+79.8%
LIVN	Buy	LIVANOVA PLC	$20,020,000	+4.7%	271,314	+2.1%	0.37%	+14.1%
ZBH	Buy	ZIMMER BIOMET HLDGS INC	$19,818,000	+66.3%	144,373	+42.7%	0.37%	+81.8%
SRRK	Buy	SCHOLAR ROCK HOLDING CORP	$19,664,000	-36.5%	2,197,100	+12.6%	0.37%	-30.8%
ITCI	Buy	INTRA CELLULAR THERAPIES INC	$19,340,000	-33.6%	2,588,990	+15.3%	0.36%	-27.7%
ARVN	New	ARVINAS INC	$17,378,000	–	806,403	–	0.32%	–
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$16,671,000	-0.5%	57,236	+0.4%	0.31%	+8.4%
WMGI	Buy	WRIGHT MED GROUP NV	$16,593,000	+16.3%	804,291	+68.1%	0.31%	+26.6%
GTHX	Buy	G1 THERAPEUTICS INC	$16,445,000	-20.2%	721,925	+7.4%	0.31%	-13.1%
CDNA	Buy	CAREDX INC	$16,339,000	-7.7%	722,655	+46.9%	0.30%	+0.7%
GMED	Buy	GLOBUS MED INCcl a	$15,217,000	+31.5%	297,666	+8.8%	0.28%	+42.9%
INSP	Buy	INSPIRE MED SYS INC	$14,856,000	+26.0%	243,457	+25.3%	0.28%	+37.3%
PODD	Buy	INSULET CORP	$14,719,000	+48.1%	89,245	+7.2%	0.27%	+61.2%
HMSY	Buy	HMS HLDGS CORP	$14,199,000	+10.0%	411,972	+3.4%	0.26%	+20.0%
HCM	Buy	HUTCHISON CHINA MEDITECH LTDsponsored adr	$13,788,000	+4.7%	788,198	+31.7%	0.26%	+13.8%
GNMK	Sell	GENMARK DIAGNOSTICS INC	$13,740,000	-10.0%	2,267,252	-3.6%	0.26%	-1.9%
IRTC	Buy	IRHYTHM TECHNOLOGIES INC	$13,667,000	-3.4%	184,419	+3.1%	0.25%	+5.4%
IART	Buy	INTEGRA LIFESCIENCES HLDGS C	$12,828,000	+19.8%	213,557	+11.4%	0.24%	+30.6%
NVRO	Buy	NEVRO CORP	$12,475,000	+36.9%	145,111	+3.2%	0.23%	+48.7%
OMCL	Buy	OMNICELL INC	$12,405,000	-13.5%	171,646	+3.0%	0.23%	-5.7%
PACB	New	PACIFIC BIOSIENCES CALIF IN	$12,249,000	–	2,373,787	–	0.23%	–
TNDM	Buy	TANDEM DIABETES CARE INC	$11,486,000	+6.1%	194,736	+16.0%	0.21%	+15.7%
SUPN	Sell	SUPERNUS PHARMACEUTICALS INC	$11,448,000	-25.9%	416,600	-10.8%	0.21%	-19.3%
AMGN	Buy	AMGEN INC	$11,166,000	+30.0%	57,700	+23.8%	0.21%	+41.5%
TRHC	Buy	TABULA RASA HEALTHCARE INC	$11,081,000	+16.1%	201,693	+5.5%	0.21%	+26.4%
OXFD	Buy	OXFORD IMMUNOTEC GLOBAL PLC	$10,609,000	+33.2%	637,972	+10.3%	0.20%	+44.9%
CHNG	Sell	CHANGE HEALTHCARE INC	$10,436,000	-28.5%	863,922	-13.6%	0.19%	-22.1%
MASI	Buy	MASIMO CORP	$10,176,000	+4.3%	68,392	+4.3%	0.19%	+13.2%
FIT	Sell	FITBIT INCcl a	$10,134,000	-37.7%	2,659,944	-28.0%	0.19%	-32.4%
QDEL	Sell	QUIDEL CORP	$9,817,000	-38.4%	160,016	-40.4%	0.18%	-32.7%
MOH	Buy	MOLINA HEALTHCARE INC	$9,352,000	-20.0%	85,239	+4.4%	0.17%	-13.0%
IDXX	Buy	IDEXX LABS INC	$9,282,000	+3.9%	34,134	+5.2%	0.17%	+13.1%
BGNE	Sell	BEIGENE LTDsponsored adr	$8,979,000	-22.1%	72,100	-22.5%	0.17%	-15.2%
QTRX	Buy	QUANTERIX CORP	$8,918,000	-33.6%	406,101	+2.1%	0.17%	-27.5%
HZNP	Buy	HORIZON THERAPEUTICS PUB LTD	$8,803,000	+36.3%	323,300	+20.4%	0.16%	+49.1%
HOLX	Buy	HOLOGIC INC	$7,836,000	+10.6%	155,208	+5.2%	0.15%	+20.7%
XENT	Buy	INTERSECT ENT INC	$7,801,000	-24.0%	458,588	+1.7%	0.14%	-17.1%
VEEV	Buy	VEEVA SYS INC	$7,769,000	-3.4%	50,884	+2.6%	0.14%	+5.1%
BIIB	Buy	BIOGEN INC	$7,532,000	+9.0%	32,350	+9.5%	0.14%	+18.6%
RMD	Buy	RESMED INC	$7,381,000	+14.9%	54,630	+3.8%	0.14%	+24.5%
XRAY	Buy	DENTSPLY SIRONA INC	$7,027,000	-3.9%	131,818	+5.2%	0.13%	+4.8%
SGEN	Buy	SEATTLE GENETICS INC	$6,943,000	+37.4%	81,300	+11.4%	0.13%	+50.0%
CVS	Buy	CVS HEALTH CORP	$6,666,000	+106.2%	105,688	+78.1%	0.12%	+125.5%
VCRA	Buy	VOCERA COMMUNICATONS INC	$6,142,000	-0.6%	249,173	+28.7%	0.11%	+7.5%
GH	Sell	GUARDANT HEALTH INC	$6,049,000	-41.5%	94,761	-20.9%	0.11%	-36.2%
MYL	New	MYLAN N V	$5,799,000	–	293,200	–	0.11%	–
QTNT	Buy	QUOTIENT LTD	$5,811,000	-15.3%	747,894	+2.0%	0.11%	-7.7%
INGN	Buy	INOGEN INC	$5,429,000	-16.0%	113,323	+17.0%	0.10%	-8.2%
PHR	New	PHREESIA INC	$5,350,000	–	220,690	–	0.10%	–
AGN	Sell	ALLERGAN PLC	$5,183,000	-3.6%	30,800	-4.0%	0.10%	+4.3%
HCAT	New	HEALTH CATALYST INC	$5,069,000	–	160,216	–	0.09%	–
TXG	New	10X GENOMICS INC	$5,040,000	–	100,000	–	0.09%	–
SDC	New	SMILEDIRECTCLUB INC	$4,858,000	–	350,000	–	0.09%	–
SILK	Buy	SILK RAOD MEDICAL INC	$4,292,000	-30.2%	131,954	+4.1%	0.08%	-23.8%
CHRS	Buy	COHERUS BIOSCIENCES INC	$4,081,000	+10.8%	201,435	+20.9%	0.08%	+20.6%
HSIC	Buy	HENRY SCHEIN INC	$4,037,000	-0.3%	63,575	+9.8%	0.08%	+8.7%
PEN	Sell	PENUMBRA INC	$3,369,000	-16.4%	25,048	-0.5%	0.06%	-8.7%
ACAD	Sell	ACADIA PHARMACEUTICALS INC	$3,253,000	+17.2%	90,400	-12.9%	0.06%	+29.8%
SWAV	Buy	SHOCKWAVE MED INC	$3,034,000	-45.5%	101,358	+3.9%	0.06%	-41.1%
AVTR	Buy	AVANTOR INC	$2,895,000	-19.0%	196,951	+5.2%	0.05%	-11.5%
PTCT	Sell	PTC THERAPEUTICS INC	$2,746,000	-26.9%	81,200	-2.8%	0.05%	-20.3%
STIM	Buy	NEURONETICS INC	$2,709,000	-33.3%	325,961	+0.4%	0.05%	-27.5%
KURA	Buy	KURA ONCOLOGY INC	$2,523,000	-11.8%	166,300	+14.5%	0.05%	-4.1%
BIO	New	BIO RAD LABS INCcl a	$2,246,000	–	6,750	–	0.04%	–
A	Sell	AGILENT TECHNOLOGIES INC	$2,284,000	-39.8%	29,800	-41.3%	0.04%	-35.4%
BNFT	Buy	BENEFITFOCUS INC	$2,154,000	-10.0%	90,463	+2.6%	0.04%	-2.4%
MDCO	Sell	MEDICINES CO	$1,445,000	-8.9%	28,900	-33.6%	0.03%	0.0%
LABD	Sell	DIREXION SHS ETF TRdaily s&p biotec	$1,393,000	-31.0%	55,000	-50.9%	0.03%	-23.5%
ASND	Sell	ASCENDIS PHARMA A Ssponsored adr	$1,310,000	-37.5%	13,600	-25.3%	0.02%	-33.3%
JNJ	New	JOHNSON & JOHNSON	$1,294,000	–	10,000	–	0.02%	–
MRTX	Sell	MIRATI THERAPEUTICS INC	$1,239,000	-44.1%	15,900	-26.0%	0.02%	-39.5%
QURE	Buy	UNIQURE NV	$1,216,000	-43.6%	30,900	+12.0%	0.02%	-37.8%
GWPH	Sell	GW PHARMACEUTICALS PLCads	$1,202,000	-43.6%	10,453	-15.4%	0.02%	-38.9%
PTLA	New	PORTOLA PHARMACEUTICALS INC	$1,172,000	–	43,700	–	0.02%	–
RGNX	Buy	REGENXBIO INC	$1,200,000	-29.4%	33,700	+1.8%	0.02%	-24.1%
BPMC	Buy	BLUEPRINT MEDICINES CORP	$1,161,000	-20.6%	15,800	+1.9%	0.02%	-12.0%
ARNA	Sell	ARENA PHARMACEUTICALS INC	$1,076,000	-60.9%	23,517	-49.9%	0.02%	-57.4%
CRL	New	CHARLES RIV LABS INTL INC	$1,099,000	–	8,300	–	0.02%	–
XLRN	New	ACCELERON PHARMA INC	$1,019,000	–	25,800	–	0.02%	–
TEVA	New	TEVA PHARMACEUTICAL INDS LTDsponsored ads	$1,028,000	–	150,000	–	0.02%	–
ZLAB	Sell	ZAI LAB LTDadr	$971,000	-72.2%	30,000	-70.0%	0.02%	-70.0%
ZGNX	New	ZOGENIX INC	$921,000	–	23,000	–	0.02%	–
FATE	Buy	FATE THERAPEUTICS INC	$933,000	-22.1%	60,100	+1.9%	0.02%	-15.0%
LH	Sell	LABORATORY CORP AMER HLDGS	$936,000	-6.4%	5,573	-3.6%	0.02%	0.0%
MCK	Sell	MCKESSON CORP	$810,000	-1.9%	5,924	-3.7%	0.02%	+7.1%
LVGO	New	LIVONGO HEALTH INC	$754,000	–	43,220	–	0.01%	–
MNTA	New	MOMENTA PHARMACEUTICALS INC	$648,000	–	50,000	–	0.01%	–
FAST	Buy	FASTENAL CO	$630,000	+97.5%	19,299	+97.0%	0.01%	+140.0%
ADMS	New	ADAMAS PHARMACEUTICALS INC	$593,000	–	116,000	–	0.01%	–
CBPO	Buy	CHINA BIOLOGIC PRODS HLDGS I	$515,000	+49.7%	4,500	+24.7%	0.01%	+66.7%
ALV	Buy	AUTOLIV INC	$536,000	+111.9%	6,800	+89.8%	0.01%	+150.0%
SQM	Buy	SOCIEDAD QUIMICA MINERA DE Cspon adr ser b	$501,000	+130.9%	18,200	+160.4%	0.01%	+125.0%
MTB	Buy	M & T BK CORP	$474,000	+61.2%	3,000	+73.3%	0.01%	+80.0%
ST	Buy	SENSATA TECHNOLOGIES HLDNG P	$496,000	+64.2%	9,900	+60.7%	0.01%	+80.0%
WSO	Buy	WATSCO INC	$474,000	+45.4%	2,800	+40.5%	0.01%	+50.0%
IPGP	Buy	IPG PHOTONICS CORP	$475,000	+43.9%	3,500	+63.5%	0.01%	+50.0%
ENTG	Buy	ENTEGRIS INC	$485,000	+49.2%	10,300	+18.3%	0.01%	+50.0%
WAB	Buy	WABTEC CORP	$460,000	+46.5%	6,400	+46.1%	0.01%	+80.0%
EA	Buy	ELECTRONIC ARTS INC	$470,000	+49.7%	4,800	+54.8%	0.01%	+80.0%
DPZ	Buy	DOMINOS PIZZA INC	$465,000	+28.5%	1,900	+46.2%	0.01%	+50.0%
VAR	Buy	VARIAN MED SYS INC	$488,000	+28.4%	4,100	+46.9%	0.01%	+50.0%
ADI	Buy	ANALOG DEVICES INC	$458,000	+36.3%	4,100	+37.9%	0.01%	+50.0%
KEX	Buy	KIRBY CORP	$485,000	+43.5%	5,900	+38.0%	0.01%	+50.0%
MCHP	Buy	MICROCHIP TECHNOLOGY INC	$465,000	+48.1%	5,000	+38.2%	0.01%	+80.0%
MTD	Buy	METTLER TOLEDO INTERNATIONAL	$493,000	+23.6%	700	+47.4%	0.01%	+28.6%
BFB	Buy	BROWN FORMAN CORPcl b	$477,000	+34.0%	7,600	+18.4%	0.01%	+50.0%
IBKR	Buy	INTERACTIVE BROKERS GROUP IN	$506,000	+62.2%	9,400	+63.3%	0.01%	+80.0%
MKL	Buy	MARKEL CORP	$473,000	+55.6%	400	+43.4%	0.01%	+80.0%
AUTL	Buy	AUTOLUS THERAPEUTICS PLCspon ads	$430,000	-21.4%	34,600	+1.8%	0.01%	-11.1%
ADBE	Buy	ADOBE INC	$414,000	+17.6%	1,500	+25.7%	0.01%	+33.3%
AXP	Buy	AMERICAN EXPRESS CO	$426,000	+15.1%	3,600	+20.0%	0.01%	+33.3%
BR	Buy	BROADRIDGE FINL SOLUTIONS IN	$423,000	+15.9%	3,400	+18.8%	0.01%	+33.3%
CERN	Buy	CERNER CORP	$423,000	+9.0%	6,200	+17.0%	0.01%	+14.3%
CLX	New	CLOROX CO DEL	$425,000	–	2,800	–	0.01%	–
CL	Buy	COLGATE PALMOLIVE CO	$448,000	+34.5%	6,100	+31.2%	0.01%	+33.3%
GGG	Buy	GRACO INC	$447,000	+29.2%	9,700	+40.5%	0.01%	+33.3%
HTHT	Buy	HUAZHU GROUP LTDsponsored ads	$446,000	+31.6%	13,500	+44.5%	0.01%	+33.3%
ICE	Buy	INTERCONTINENTAL EXCHANGE IN	$443,000	+34.2%	4,800	+25.1%	0.01%	+33.3%
JD	Buy	JD COM INCspon adr cl a	$415,000	+11.9%	14,700	+19.9%	0.01%	+33.3%
LYV	Buy	LIVE NATION ENTERTAINMENT IN	$411,000	+24.2%	6,200	+24.0%	0.01%	+33.3%
MKC	Buy	MCCORMICK & CO INC	$438,000	+18.1%	2,800	+17.1%	0.01%	+33.3%
MCO	Buy	MOODYS CORP	$410,000	+12.9%	2,000	+7.6%	0.01%	+33.3%
PAYX	New	PAYCHEX INC	$447,000	–	5,400	–	0.01%	–
POL	Buy	POLYONE CORP	$444,000	+56.3%	13,600	+50.5%	0.01%	+60.0%
POOL	Buy	POOL CORPORATION	$444,000	+21.0%	2,200	+14.5%	0.01%	+33.3%
SPGI	Buy	S&P GLOBAL INC	$416,000	+18.2%	1,700	+10.1%	0.01%	+33.3%
SWKS	Buy	SKYWORKS SOLUTIONS INC	$452,000	+47.2%	5,700	+43.3%	0.01%	+60.0%
TRMB	Buy	TRIMBLE INC	$454,000	+26.5%	11,700	+47.0%	0.01%	+33.3%
VNE	Buy	VEONEER INCORPORATED	$445,000	+166.5%	29,700	+207.5%	0.01%	+166.7%
LIN	New	LINDE PLC	$358,000	–	1,848	–	0.01%	–
XLNX	New	XILINX INC	$403,000	–	4,200	–	0.01%	–
VRSN	Buy	VERISIGN INC	$396,000	+8.5%	2,100	+20.4%	0.01%	+16.7%
CTRP	Buy	CTRIP COM INTL LTDsponsored ads	$384,000	+15.3%	13,100	+45.0%	0.01%	+16.7%
BKNG	Buy	BOOKING HLDGS INC	$393,000	+29.3%	200	+23.5%	0.01%	+40.0%
STML	New	STEMLINE THERAPEUTICS INC	$328,000	–	31,500	–	0.01%	–
ALXN	New	ALEXION PHARMACEUTICALS INCcall	$113,000	–	150	–	0.00%	–
CRM	Exit	SALESFORCE COM INC	$0	–	-1,956	–	-0.01%	–
USB	Exit	US BANCORP DEL	$0	–	-5,662	–	-0.01%	–
BIS	Exit	PROSHARES TRultsh nasd biot	$0	–	-25,000	–	-0.01%	–
AFMD	Exit	AFFIMED N V	$0	–	-167,500	–	-0.01%	–
MELI	Exit	MERCADOLIBRE INC	$0	–	-835	–	-0.01%	–
VKTX	Exit	VIKING THERAPEUTICS INC	$0	–	-96,000	–	-0.01%	–
ANAB	Exit	ANAPTYSBIO INC	$0	–	-17,000	–	-0.02%	–
WCG	Exit	WELLCARE HEALTH PLANS INC	$0	–	-4,851	–	-0.02%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL INC	$0	–	-22,800	–	-0.02%	–
FOLD	Exit	AMICUS THERAPEUTICS INC	$0	–	-150,000	–	-0.03%	–
BLUE	Exit	BLUEBIRD BIO INC	$0	–	-18,200	–	-0.04%	–
CSLT	Exit	CASTLIGHT HEALTH INCcl b	$0	–	-800,000	–	-0.04%	–
AVDR	Exit	AVEDRO INC	$0	–	-804,379	–	-0.27%	–

Q2 2019

			Value		Shares		↓ Weighting
IONS	New	IONIS PHARMACEUTICALS INC	$511,404,000	–	7,957,128	–	8.73%	–
INCY	New	INCYTE CORP	$314,153,000	–	3,697,650	–	5.36%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$299,426,000	–	3,546,444	–	5.11%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$260,489,000	–	1,420,489	–	4.45%	–
SAGE	New	SAGE THERAPEUTICS INC	$241,935,000	–	1,321,404	–	4.13%	–
ESPR	New	ESPERION THERAPEUTICS INC NEW	$188,750,000	–	4,057,411	–	3.22%	–
ALXN	New	ALEXION PHARMACEUTICALS INC	$175,700,000	–	1,341,428	–	3.00%	–
CELG	New	CELGENE CORP	$171,014,000	–	1,850,000	–	2.92%	–
RDUS	New	RADIUS HEALTH INC	$166,642,000	–	6,840,785	–	2.84%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$156,031,000	–	3,128,134	–	2.66%	–
HALO	New	HALOZYME THERAPEUTICS INC	$141,698,000	–	8,247,860	–	2.42%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$139,852,000	–	1,927,394	–	2.39%	–
ARGX	New	ARGENX SEsponsored adr	$133,742,000	–	944,639	–	2.28%	–
ANTM	New	ANTHEM INC	$101,804,000	–	360,739	–	1.74%	–
TDOC	New	TELADOC HEALTH INC	$95,299,000	–	1,435,012	–	1.63%	–
NKTR	New	NEKTAR THERAPEUTICS	$93,671,000	–	2,632,686	–	1.60%	–
ISRG	New	INTUITIVE SURGICAL INC	$88,377,000	–	168,482	–	1.51%	–
ILMN	New	ILLUMINA INC	$84,009,000	–	228,191	–	1.43%	–
ALGN	New	ALIGN TECHNOLOGY INC	$83,915,000	–	306,595	–	1.43%	–
EXEL	New	EXELIXIS INC	$82,890,000	–	3,878,800	–	1.42%	–
ABT	New	ABBOTT LABS	$80,534,000	–	957,595	–	1.38%	–
MDT	New	MEDTRONIC PLC	$75,907,000	–	779,411	–	1.30%	–
MGNX	New	MACROGENICS INC	$74,588,000	–	4,395,264	–	1.27%	–
VYGR	New	VOYAGER THERAPEUTICS INC	$72,957,000	–	2,680,283	–	1.25%	–
AKCA	New	AKCEA THERAPEUTICS INC	$72,713,000	–	3,100,768	–	1.24%	–
GILD	New	GILEAD SCIENCES INC	$72,235,000	–	1,069,200	–	1.23%	–
MRNA	New	MODERNA INC	$69,163,000	–	4,724,246	–	1.18%	–
HUM	New	HUMANA INC	$63,994,000	–	241,212	–	1.09%	–
MYOK	New	MYOKARDIA INC	$63,423,000	–	1,264,913	–	1.08%	–
BSX	New	BOSTON SCIENTIFIC CORP	$59,346,000	–	1,380,782	–	1.01%	–
ICPT	New	INTERCEPT PHARMACEUTICALS IN	$56,638,000	–	711,803	–	0.97%	–
BOLD	New	AUDENTES THERAPEUTICS INC	$51,853,000	–	1,369,604	–	0.88%	–
DHR	New	DANAHER CORPORATION	$50,122,000	–	350,698	–	0.86%	–
ALDR	New	ALDER BIOPHARMACEUTICALS INC	$48,478,000	–	4,118,806	–	0.83%	–
UNH	New	UNITEDHEALTH GROUP INC	$47,434,000	–	194,394	–	0.81%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$47,355,000	–	332,173	–	0.81%	–
WVE	New	WAVE LIFE SCIENCES LTD	$39,526,000	–	1,515,002	–	0.68%	–
SGMO	New	SANGAMO THERAPEUTICS INC	$39,311,000	–	3,650,000	–	0.67%	–
BMY	New	BRISTOL MYERS SQUIBB CO	$38,802,000	–	855,609	–	0.66%	–
CRSP	New	CRISPR THERAPEUTICS AGnamen akt	$38,173,000	–	810,462	–	0.65%	–
BDX	New	BECTON DICKINSON & CO	$37,724,000	–	149,692	–	0.64%	–
CNC	New	CENTENE CORP DEL	$35,372,000	–	674,525	–	0.60%	–
MYOV	New	MYOVANT SCIENCES LTD	$35,386,000	–	3,910,109	–	0.60%	–
ABMD	New	ABIOMED INC	$35,083,000	–	134,682	–	0.60%	–
CI	New	CIGNA CORP NEW	$33,204,000	–	210,754	–	0.57%	–
SYK	New	STRYKER CORP	$32,721,000	–	159,163	–	0.56%	–
EW	New	EDWARDS LIFESCIENCES CORP	$32,138,000	–	173,966	–	0.55%	–
SRRK	New	SCHOLAR ROCK HOLDING CORP	$30,956,000	–	1,951,839	–	0.53%	–
QGEN	New	QIAGEN NV	$30,190,000	–	744,513	–	0.52%	–
ITCI	New	INTRA CELLULAR THERAPIES INC	$29,147,000	–	2,245,500	–	0.50%	–
FIXX	New	HOMOLOGY MEDICINES INC	$27,440,000	–	1,402,122	–	0.47%	–
BAX	New	BAXTER INTL INC	$25,736,000	–	314,237	–	0.44%	–
HCA	New	HCA HEALTHCARE INC	$25,242,000	–	186,745	–	0.43%	–
DXCM	New	DEXCOM INC	$24,744,000	–	165,136	–	0.42%	–
HRC	New	HILL ROM HLDGS INC	$24,397,000	–	233,198	–	0.42%	–
AMED	New	AMEDISYS INC	$21,163,000	–	174,310	–	0.36%	–
GTHX	New	G1 THERAPEUTICS INC	$20,601,000	–	671,925	–	0.35%	–
LIVN	New	LIVANOVA PLC	$19,117,000	–	265,666	–	0.33%	–
EVH	New	EVOLENT HEALTH INCcl a	$18,675,000	–	2,349,000	–	0.32%	–
CDNA	New	CAREDX INC	$17,707,000	–	492,008	–	0.30%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$16,747,000	–	57,024	–	0.29%	–
FIT	New	FITBIT INCcl a	$16,265,000	–	3,696,530	–	0.28%	–
QDEL	New	QUIDEL CORP	$15,926,000	–	268,470	–	0.27%	–
INSM	New	INSMED INC	$15,884,000	–	620,459	–	0.27%	–
AVDR	New	AVEDRO INC	$15,798,000	–	804,379	–	0.27%	–
SUPN	New	SUPERNUS PHARMACEUTICALS INC	$15,453,000	–	467,000	–	0.26%	–
GNMK	New	GENMARK DIAGNOSTICS INC	$15,271,000	–	2,353,067	–	0.26%	–
CHNG	New	CHANGE HEALTHCARE INC	$14,600,000	–	1,000,000	–	0.25%	–
OMCL	New	OMNICELL INC	$14,342,000	–	166,715	–	0.24%	–
WMGI	New	WRIGHT MED GROUP NV	$14,269,000	–	478,495	–	0.24%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$14,143,000	–	178,848	–	0.24%	–
QTRX	New	QUANTERIX CORP	$13,434,000	–	397,569	–	0.23%	–
HCM	New	HUTCHISON CHINA MEDITECH LTDsponsored adr	$13,163,000	–	598,310	–	0.22%	–
HMSY	New	HMS HLDGS CORP	$12,906,000	–	398,442	–	0.22%	–
TFX	New	TELEFLEX INC	$12,175,000	–	36,766	–	0.21%	–
ZBH	New	ZIMMER BIOMET HLDGS INC	$11,915,000	–	101,199	–	0.20%	–
INSP	New	INSPIRE MED SYS INC	$11,787,000	–	194,340	–	0.20%	–
MOH	New	MOLINA HEALTHCARE INC	$11,689,000	–	81,661	–	0.20%	–
GMED	New	GLOBUS MED INCcl a	$11,568,000	–	273,482	–	0.20%	–
BGNE	New	BEIGENE LTDsponsored adr	$11,527,000	–	93,000	–	0.20%	–
TNDM	New	TANDEM DIABETES CARE INC	$10,829,000	–	167,847	–	0.18%	–
COO	New	COOPER COS INC	$10,770,000	–	31,969	–	0.18%	–
IART	New	INTEGRA LIFESCIENCES HLDGS C	$10,708,000	–	191,733	–	0.18%	–
GH	New	GUARDANT HEALTH INC	$10,346,000	–	119,848	–	0.18%	–
XENT	New	INTERSECT ENT INC	$10,258,000	–	450,718	–	0.18%	–
PODD	New	INSULET CORP	$9,938,000	–	83,246	–	0.17%	–
MASI	New	MASIMO CORP	$9,761,000	–	65,592	–	0.17%	–
TRHC	New	TABULA RASA HEALTHCARE INC	$9,545,000	–	191,175	–	0.16%	–
KZR	New	KEZAR LIFE SCIENCES INC	$9,487,000	–	1,230,523	–	0.16%	–
NVRO	New	NEVRO CORP	$9,112,000	–	140,548	–	0.16%	–
IDXX	New	IDEXX LABS INC	$8,934,000	–	32,449	–	0.15%	–
AMGN	New	AMGEN INC	$8,587,000	–	46,600	–	0.15%	–
GKOS	New	GLAUKOS CORP	$8,086,000	–	107,235	–	0.14%	–
VEEV	New	VEEVA SYS INC	$8,039,000	–	49,590	–	0.14%	–
OXFD	New	OXFORD IMMUNOTEC GLOBAL PLC	$7,962,000	–	578,615	–	0.14%	–
XRAY	New	DENTSPLY SIRONA INC	$7,313,000	–	125,313	–	0.12%	–
HOLX	New	HOLOGIC INC	$7,085,000	–	147,548	–	0.12%	–
BIIB	New	BIOGEN INC	$6,911,000	–	29,550	–	0.12%	–
QTNT	New	QUOTIENT LTD	$6,858,000	–	733,441	–	0.12%	–
INGN	New	INOGEN INC	$6,465,000	–	96,843	–	0.11%	–
HZNP	New	HORIZON THERAPEUTICS PUB LTD	$6,460,000	–	268,500	–	0.11%	–
RMD	New	RESMED INC	$6,422,000	–	52,626	–	0.11%	–
VCRA	New	VOCERA COMMUNICATONS INC	$6,181,000	–	193,634	–	0.11%	–
SILK	New	SILK RAOD MEDICAL INC	$6,145,000	–	126,810	–	0.10%	–
SWAV	New	SHOCKWAVE MED INC	$5,569,000	–	97,547	–	0.10%	–
AGN	New	ALLERGAN PLC	$5,375,000	–	32,100	–	0.09%	–
SGEN	New	SEATTLE GENETICS INC	$5,052,000	–	73,000	–	0.09%	–
MTLS	New	MATERIALISE NVsponsored ads	$4,700,000	–	240,770	–	0.08%	–
HSIC	New	HENRY SCHEIN INC	$4,048,000	–	57,917	–	0.07%	–
STIM	New	NEURONETICS INC	$4,063,000	–	324,779	–	0.07%	–
PEN	New	PENUMBRA INC	$4,029,000	–	25,180	–	0.07%	–
CDTX	New	CIDARA THERAPEUTICS INC	$3,856,000	–	2,295,272	–	0.07%	–
A	New	AGILENT TECHNOLOGIES INC	$3,792,000	–	50,782	–	0.06%	–
PTCT	New	PTC THERAPEUTICS INC	$3,758,000	–	83,500	–	0.06%	–
CHRS	New	COHERUS BIOSCIENCES INC	$3,683,000	–	166,635	–	0.06%	–
AVTR	New	AVANTOR INC	$3,574,000	–	187,231	–	0.06%	–
ZLAB	New	ZAI LAB LTDadr	$3,487,000	–	100,000	–	0.06%	–
CVS	New	CVS HEALTH CORP	$3,233,000	–	59,326	–	0.06%	–
SYNH	New	SYNEOS HEALTH INCcl a	$3,168,000	–	62,000	–	0.05%	–
KURA	New	KURA ONCOLOGY INC	$2,859,000	–	145,200	–	0.05%	–
ACAD	New	ACADIA PHARMACEUTICALS INC	$2,775,000	–	103,800	–	0.05%	–
ARNA	New	ARENA PHARMACEUTICALS INC	$2,751,000	–	46,917	–	0.05%	–
CSLT	New	CASTLIGHT HEALTH INCcl b	$2,584,000	–	800,000	–	0.04%	–
BNFT	New	BENEFITFOCUS INC	$2,394,000	–	88,163	–	0.04%	–
BLUE	New	BLUEBIRD BIO INC	$2,315,000	–	18,200	–	0.04%	–
MRTX	New	MIRATI THERAPEUTICS INC	$2,215,000	–	21,500	–	0.04%	–
QURE	New	UNIQURE NV	$2,157,000	–	27,600	–	0.04%	–
ASND	New	ASCENDIS PHARMA A Ssponsored adr	$2,096,000	–	18,200	–	0.04%	–
GWPH	New	GW PHARMACEUTICALS PLCads	$2,130,000	–	12,353	–	0.04%	–
CTLT	New	CATALENT INC	$2,033,000	–	37,500	–	0.04%	–
LABD	New	DIREXION SHS ETF TRdaily s&p biotec	$2,018,000	–	112,000	–	0.03%	–
FOLD	New	AMICUS THERAPEUTICS INC	$1,872,000	–	150,000	–	0.03%	–
PFE	New	PFIZER INC	$1,733,000	–	40,000	–	0.03%	–
RGNX	New	REGENXBIO INC	$1,700,000	–	33,100	–	0.03%	–
MDCO	New	MEDICINES CO	$1,586,000	–	43,500	–	0.03%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL INC	$1,448,000	–	22,800	–	0.02%	–
BPMC	New	BLUEPRINT MEDICINES CORP	$1,462,000	–	15,500	–	0.02%	–
WCG	New	WELLCARE HEALTH PLANS INC	$1,383,000	–	4,851	–	0.02%	–
FATE	New	FATE THERAPEUTICS INC	$1,198,000	–	59,000	–	0.02%	–
LH	New	LABORATORY CORP AMER HLDGS	$1,000,000	–	5,783	–	0.02%	–
ANAB	New	ANAPTYSBIO INC	$959,000	–	17,000	–	0.02%	–
VKTX	New	VIKING THERAPEUTICS INC	$797,000	–	96,000	–	0.01%	–
MCK	New	MCKESSON CORP	$826,000	–	6,149	–	0.01%	–
MELI	New	MERCADOLIBRE INC	$511,000	–	835	–	0.01%	–
AUTL	New	AUTOLUS THERAPEUTICS PLCspon ads	$547,000	–	34,000	–	0.01%	–
AFMD	New	AFFIMED N V	$481,000	–	167,500	–	0.01%	–
MSCI	New	MSCI INC	$426,000	–	1,786	–	0.01%	–
CERN	New	CERNER CORP	$388,000	–	5,298	–	0.01%	–
EL	New	LAUDER ESTEE COS INCcl a	$412,000	–	2,248	–	0.01%	–
MKTX	New	MARKETAXESS HLDGS INC	$425,000	–	1,322	–	0.01%	–
BIS	New	PROSHARES TRultsh nasd biot	$426,000	–	25,000	–	0.01%	–
MTD	New	METTLER TOLEDO INTERNATIONAL	$399,000	–	475	–	0.01%	–
GGG	New	GRACO INC	$346,000	–	6,903	–	0.01%	–
KOS	New	KOSMOS ENERGY LTD	$376,000	–	60,000	–	0.01%	–
KEX	New	KIRBY CORP	$338,000	–	4,274	–	0.01%	–
MKC	New	MCCORMICK & CO INC	$371,000	–	2,391	–	0.01%	–
JD	New	JD COM INCspon adr cl a	$371,000	–	12,263	–	0.01%	–
ICE	New	INTERCONTINENTAL EXCHANGE IN	$330,000	–	3,837	–	0.01%	–
MCO	New	MOODYS CORP	$363,000	–	1,858	–	0.01%	–
IPGP	New	IPG PHOTONICS CORP	$330,000	–	2,141	–	0.01%	–
HTHT	New	HUAZHU GROUP LTDsponsored ads	$339,000	–	9,344	–	0.01%	–
ADBE	New	ADOBE INC	$352,000	–	1,193	–	0.01%	–
LYV	New	LIVE NATION ENTERTAINMENT IN	$331,000	–	5,000	–	0.01%	–
POOL	New	POOL CORPORATION	$367,000	–	1,921	–	0.01%	–
ENTG	New	ENTEGRIS INC	$325,000	–	8,706	–	0.01%	–
SPGI	New	S&P GLOBAL INC	$352,000	–	1,544	–	0.01%	–
DPZ	New	DOMINOS PIZZA INC	$362,000	–	1,300	–	0.01%	–
CTRP	New	CTRIP COM INTL LTDsponsored ads	$333,000	–	9,032	–	0.01%	–
CL	New	COLGATE PALMOLIVE CO	$333,000	–	4,651	–	0.01%	–
SBUX	New	STARBUCKS CORP	$363,000	–	4,334	–	0.01%	–
BFB	New	BROWN FORMAN CORPcl b	$356,000	–	6,417	–	0.01%	–
BR	New	BROADRIDGE FINL SOLUTIONS IN	$365,000	–	2,862	–	0.01%	–
TRMB	New	TRIMBLE INC	$359,000	–	7,958	–	0.01%	–
TYL	New	TYLER TECHNOLOGIES INC	$329,000	–	1,525	–	0.01%	–
VAR	New	VARIAN MED SYS INC	$380,000	–	2,791	–	0.01%	–
VRSN	New	VERISIGN INC	$365,000	–	1,744	–	0.01%	–
VRSK	New	VERISK ANALYTICS INC	$365,000	–	2,489	–	0.01%	–
BLKB	New	BLACKBAUD INC	$343,000	–	4,107	–	0.01%	–
WSO	New	WATSCO INC	$326,000	–	1,993	–	0.01%	–
CBPO	New	CHINA BIOLOGIC PRODS HLDGS I	$344,000	–	3,609	–	0.01%	–
AZPN	New	ASPEN TECHNOLOGY INC	$373,000	–	3,000	–	0.01%	–
ANSS	New	ANSYS INC	$369,000	–	1,802	–	0.01%	–
ADI	New	ANALOG DEVICES INC	$336,000	–	2,973	–	0.01%	–
AXP	New	AMERICAN EXPRESS CO	$370,000	–	3,000	–	0.01%	–
SWKS	New	SKYWORKS SOLUTIONS INC	$307,000	–	3,978	–	0.01%	–
USB	New	US BANCORP DEL	$297,000	–	5,662	–	0.01%	–
WAB	New	WABTEC CORP	$314,000	–	4,382	–	0.01%	–
MTB	New	M & T BK CORP	$294,000	–	1,731	–	0.01%	–
BKNG	New	BOOKING HLDGS INC	$304,000	–	162	–	0.01%	–
POL	New	POLYONE CORP	$284,000	–	9,035	–	0.01%	–
IBKR	New	INTERACTIVE BROKERS GROUP IN	$312,000	–	5,757	–	0.01%	–
CRM	New	SALESFORCE COM INC	$297,000	–	1,956	–	0.01%	–
MCHP	New	MICROCHIP TECHNOLOGY INC	$314,000	–	3,617	–	0.01%	–
EA	New	ELECTRONIC ARTS INC	$314,000	–	3,100	–	0.01%	–
MKL	New	MARKEL CORP	$304,000	–	279	–	0.01%	–
FAST	New	FASTENAL CO	$319,000	–	9,798	–	0.01%	–
ST	New	SENSATA TECHNOLOGIES HLDNG P	$302,000	–	6,162	–	0.01%	–
ALV	New	AUTOLIV INC	$253,000	–	3,582	–	0.00%	–
SQM	New	SOCIEDAD QUIMICA MINERA DE Cspon adr ser b	$217,000	–	6,990	–	0.00%	–
VNE	New	VEONEER INCORPORATED	$167,000	–	9,658	–	0.00%	–
CVET	New	COVETRUS INC	$37,000	–	1,520	–	0.00%	–

Q4 2018

			Value		Shares		↓ Weighting
IOVA	Exit	IOVANCE BIOTHERAPEUTICS INC	$0	–	-25,000	–	-0.02%	–
NTLA	Exit	INTELLIA THERAPEUTICS INC	$0	–	-16,434	–	-0.03%	–
HCSG	Exit	HEALTHCARE SVCS GRP INC	$0	–	-15,000	–	-0.04%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-8,000	–	-0.04%	–
PINC	Exit	PREMIER INCcl a	$0	–	-15,100	–	-0.04%	–
VAR	Exit	VARIAN MED SYS INC	$0	–	-6,300	–	-0.04%	–
PTLA	Exit	PORTOLA PHARMACEUTICALS INC	$0	–	-26,650	–	-0.04%	–
QURE	Exit	UNIQURE NV	$0	–	-19,900	–	-0.05%	–
ADAP	Exit	ADAPTIMMUNE THERAPEUTICS PLCsponds adr	$0	–	-58,535	–	-0.05%	–
VYGR	Exit	VOYAGER THERAPEUTICS INC	$0	–	-43,422	–	-0.05%	–
MRK	Exit	MERCK & CO INC	$0	–	-12,500	–	-0.06%	–
XLRN	Exit	ACCELERON PHARMA INC	$0	–	-16,200	–	-0.06%	–
PTCT	Exit	PTC THERAPEUTICS INC	$0	–	-22,500	–	-0.07%	–
MCK	Exit	MCKESSON CORP	$0	–	-8,503	–	-0.07%	–
GWPH	Exit	GW PHARMACEUTICALS PLCads	$0	–	-6,629	–	-0.07%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-54,600	–	-0.08%	–
ACAD	Exit	ACADIA PHARMACEUTICALS INC	$0	–	-57,000	–	-0.08%	–
MRTX	Exit	MIRATI THERAPEUTICS INC	$0	–	-25,000	–	-0.08%	–
EGRX	Exit	EAGLE PHARMACEUTICALS INC	$0	–	-18,000	–	-0.08%	–
TEVA	Exit	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$0	–	-60,000	–	-0.08%	–
PFE	Exit	PFIZER INC	$0	–	-29,200	–	-0.08%	–
SYNH	Exit	SYNEOS HEALTH INCcl a	$0	–	-26,156	–	-0.09%	–
CLLS	Exit	CELLECTIS S Asponsored ads	$0	–	-49,600	–	-0.09%	–
ARNA	Exit	ARENA PHARMACEUTICALS INC	$0	–	-30,817	–	-0.09%	–
AET	Exit	AETNA INC NEW	$0	–	-7,100	–	-0.09%	–
IRWD	Exit	IRONWOOD PHARMACEUTICALS INC	$0	–	-79,400	–	-0.09%	–
TSRO	Exit	TESARO INC	$0	–	-38,550	–	-0.10%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-19,861	–	-0.10%	–
SAGE	Exit	SAGE THERAPEUTICS INC	$0	–	-11,200	–	-0.10%	–
ANGO	Exit	ANGIODYNAMICS INC	$0	–	-75,700	–	-0.10%	–
BLUE	Exit	BLUEBIRD BIO INC	$0	–	-11,400	–	-0.11%	–
RGNX	Exit	REGENXBIO INC	$0	–	-23,300	–	-0.11%	–
PODD	Exit	INSULET CORP	$0	–	-18,000	–	-0.12%	–
BGNE	Exit	BEIGENE LTDsponsored adr	$0	–	-11,620	–	-0.13%	–
SRPT	Exit	SAREPTA THERAPEUTICS INC	$0	–	-13,100	–	-0.13%	–
AMRX	Exit	AMNEAL PHARMACEUTICALS INC	$0	–	-95,000	–	-0.13%	–
CSLT	Exit	CASTLIGHT HEALTH INCcl b	$0	–	-888,842	–	-0.15%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL INC	$0	–	-31,850	–	-0.15%	–
MASI	Exit	MASIMO CORP	$0	–	-19,476	–	-0.15%	–
AGN	Exit	ALLERGAN PLC	$0	–	-13,000	–	-0.16%	–
MDSO	Exit	MEDIDATA SOLUTIONS INC	$0	–	-36,907	–	-0.17%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-20,000	–	-0.18%	–
PEN	Exit	PENUMBRA INC	$0	–	-19,142	–	-0.18%	–
MTLS	Exit	MATERIALISE NVsponsored ads	$0	–	-210,731	–	-0.18%	–
ICPT	Exit	INTERCEPT PHARMACEUTICALS IN	$0	–	-24,148	–	-0.19%	–
LGND	Exit	LIGAND PHARMACEUTICALS INC	$0	–	-11,270	–	-0.20%	–
AMED	Exit	AMEDISYS INC	$0	–	-25,204	–	-0.20%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-55,520	–	-0.22%	–
IBB	Exit	ISHARES TRnasdaq biotech	$0	–	-28,000	–	-0.22%	–
CHRS	Exit	COHERUS BIOSCIENCES INC	$0	–	-215,935	–	-0.23%	–
VEEV	Exit	VEEVA SYS INC	$0	–	-32,691	–	-0.23%	–
STIM	Exit	NEURONETICS INC	$0	–	-111,907	–	-0.23%	–
OXFD	Exit	OXFORD IMMUNOTEC GLOBAL PLC	$0	–	-221,837	–	-0.23%	–
INCY	Exit	INCYTE CORP	$0	–	-52,350	–	-0.23%	–
SGEN	Exit	SEATTLE GENETICS INC	$0	–	-46,950	–	-0.23%	–
ENDP	Exit	ENDO INTL PLC	$0	–	-217,392	–	-0.23%	–
CERN	Exit	CERNER CORP	$0	–	-59,146	–	-0.24%	–
INSP	Exit	INSPIRE MED SYS INC	$0	–	-90,696	–	-0.24%	–
TNDM	Exit	TANDEM DIABETES CARE INC	$0	–	-97,195	–	-0.26%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-110,878	–	-0.26%	–
ESRX	Exit	EXPRESS SCRIPTS HLDG CO	$0	–	-44,500	–	-0.27%	–
HZNP	Exit	HORIZON PHARMA PLC	$0	–	-221,678	–	-0.28%	–
HSIC	Exit	SCHEIN HENRY INC	$0	–	-51,368	–	-0.28%	–
NVRO	Exit	NEVRO CORP	$0	–	-80,415	–	-0.29%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-47,869	–	-0.29%	–
TFX	Exit	TELEFLEX INC	$0	–	-17,792	–	-0.30%	–
QGEN	Exit	QIAGEN NV	$0	–	-134,189	–	-0.32%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-41,550	–	-0.32%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-36,888	–	-0.33%	–
QTNT	Exit	QUOTIENT LTD	$0	–	-721,858	–	-0.35%	–
INGN	Exit	INOGEN INC	$0	–	-23,261	–	-0.36%	–
IDXX	Exit	IDEXX LABS INC	$0	–	-24,307	–	-0.38%	–
COO	Exit	COOPER COS INC	$0	–	-22,811	–	-0.40%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-69,661	–	-0.42%	–
QTRX	Exit	QUANTERIX CORP	$0	–	-313,230	–	-0.43%	–
XENT	Exit	INTERSECT ENT INC	$0	–	-234,227	–	-0.43%	–
TRHC	Exit	TABULA RASA HEALTHCARE INC	$0	–	-86,884	–	-0.45%	–
HMSY	Exit	HMS HLDGS CORP	$0	–	-227,020	–	-0.47%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-50,478	–	-0.48%	–
OMCL	Exit	OMNICELL INC	$0	–	-104,650	–	-0.48%	–
AMGN	Exit	AMGEN INC	$0	–	-36,950	–	-0.49%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-40,494	–	-0.50%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-34,471	–	-0.53%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-151,251	–	-0.54%	–
WCG	Exit	WELLCARE HEALTH PLANS INC	$0	–	-28,269	–	-0.58%	–
IART	Exit	INTEGRA LIFESCIENCES HLDGS C	$0	–	-141,620	–	-0.59%	–
CDNA	Exit	CAREDX INC	$0	–	-337,049	–	-0.62%	–
GNMK	Exit	GENMARK DIAGNOSTICS INC	$0	–	-1,339,502	–	-0.62%	–
DXCM	Exit	DEXCOM INC	$0	–	-71,647	–	-0.65%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-25,480	–	-0.65%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-137,500	–	-0.67%	–
RMD	Exit	RESMED INC	$0	–	-93,192	–	-0.68%	–
INSM	Exit	INSMED INC	$0	–	-566,301	–	-0.73%	–
SHPG	Exit	SHIRE PLCsponsored adr	$0	–	-64,185	–	-0.74%	–
ZBH	Exit	ZIMMER BIOMET HLDGS INC	$0	–	-92,104	–	-0.77%	–
HCM	Exit	HUTCHISON CHINA MEDITECH LTDsponsored adr	$0	–	-400,029	–	-0.82%	–
FIT	Exit	FITBIT INCcl a	$0	–	-2,513,900	–	-0.85%	–
BIIB	Exit	BIOGEN INC	$0	–	-39,245	–	-0.88%	–
PACB	Exit	PACIFIC BIOSCIENCES OF CALIF INC	$0	–	-2,575,000	–	-0.88%	–
LIVN	Exit	LIVANOVA PLC	$0	–	-116,443	–	-0.92%	–
AKCA	Exit	AKCEA THERAPEUTICS INC	$0	–	-418,496	–	-0.93%	–
HOLX	Exit	HOLOGIC INC	$0	–	-361,894	–	-0.94%	–
ABMD	Exit	ABIOMED INC	$0	–	-33,135	–	-0.94%	–
ALDR	Exit	ALDER BIOPHARMACEUTICALS INC	$0	–	-905,254	–	-0.96%	–
KTWO	Exit	K2M GROUP HLDGS INC	$0	–	-552,054	–	-0.96%	–
MGNX	Exit	MACROGENICS INC	$0	–	-724,302	–	-0.98%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-310,536	–	-1.02%	–
LH	Exit	LABORATORY CORP AMER HLDGS	$0	–	-94,040	–	-1.04%	–
WBA	Exit	WALGREENS BOOTS ALLIANCE INC	$0	–	-226,018	–	-1.04%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NEW	$0	–	-391,852	–	-1.10%	–
HRC	Exit	HILL ROM HLDGS INC	$0	–	-185,689	–	-1.11%	–
WMGI	Exit	WRIGHT MED GROUP NV	$0	–	-622,692	–	-1.15%	–
PRAH	Exit	PRA HEALTH SCIENCES INC	$0	–	-166,400	–	-1.16%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-219,891	–	-1.22%	–
SUPN	Exit	SUPERNUS PHARMACEUTICALS INC	$0	–	-386,500	–	-1.23%	–
BAX	Exit	BAXTER INTL INC	$0	–	-263,348	–	-1.29%	–
MYL	Exit	MYLAN N V	$0	–	-565,350	–	-1.31%	–
BMY	Exit	BRISTOL MYERS SQUIBB CO	$0	–	-341,729	–	-1.35%	–
ABC	Exit	AMERISOURCEBERGEN CORP	$0	–	-238,853	–	-1.40%	–
SYK	Exit	STRYKER CORP	$0	–	-141,380	–	-1.59%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INC	$0	–	-183,080	–	-1.61%	–
DHR	Exit	DANAHER CORP DEL	$0	–	-253,016	–	-1.74%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-105,413	–	-1.74%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-218,021	–	-2.00%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-123,848	–	-2.09%	–
HUM	Exit	HUMANA INC	$0	–	-98,510	–	-2.12%	–
CI	Exit	CIGNA CORPORATION	$0	–	-169,463	–	-2.24%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-213,758	–	-2.28%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-978,929	–	-2.39%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-253,333	–	-2.80%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-496,446	–	-3.10%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-87,868	–	-3.20%	–
TDOC	Exit	TELADOC HEALTH INC	$0	–	-586,520	–	-3.21%	–
ILMN	Exit	ILLUMINA INC	$0	–	-147,707	–	-3.44%	–
CELG	Exit	CELGENE CORP	$0	–	-606,000	–	-3.44%	–
ABT	Exit	ABBOTT LABS	$0	–	-766,710	–	-3.57%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-146,310	–	-3.63%	–
ANTM	Exit	ANTHEM INC	$0	–	-224,188	–	-3.90%	–

Q3 2018

			Value		Shares		↓ Weighting
ANTM	Buy	ANTHEM INC	$61,439,000	+20.9%	224,188	+5.0%	3.90%	-10.1%
ALGN	Buy	ALIGN TECHNOLOGY INC	$57,239,000	+27.7%	146,310	+11.6%	3.63%	-5.0%
ABT	Buy	ABBOTT LABS	$56,246,000	+62.1%	766,710	+34.8%	3.57%	+20.6%
CELG	Buy	CELGENE CORP	$54,231,000	+28.2%	606,000	+13.7%	3.44%	-4.6%
ILMN	Buy	ILLUMINA INC	$54,217,000	+37.7%	147,707	+4.8%	3.44%	+2.4%
TDOC	Buy	TELADOC HEALTH INC	$50,646,000	+53.0%	586,520	+2.9%	3.21%	+13.9%
ISRG	Buy	INTUITIVE SURGICAL INC	$50,436,000	+20.1%	87,868	+0.1%	3.20%	-10.6%
MDT	Buy	MEDTRONIC PLC	$48,835,000	+41.9%	496,446	+23.5%	3.10%	+5.6%
EW	Buy	EDWARDS LIFESCIENCES CORP	$44,105,000	+47.3%	253,333	+23.2%	2.80%	+9.6%
BSX	Buy	BOSTON SCIENTIFIC CORP	$37,689,000	+40.5%	978,929	+19.3%	2.39%	+4.5%
JAZZ	Buy	JAZZ PHARMACEUTICALS PLC	$35,939,000	+26.5%	213,758	+29.6%	2.28%	-5.9%
CI	Buy	CIGNA CORPORATION	$35,291,000	+64.5%	169,463	+34.2%	2.24%	+22.4%
HUM	Buy	HUMANA INC	$33,348,000	+29.0%	98,510	+13.4%	2.12%	-4.0%
UNH	Buy	UNITEDHEALTH GROUP INC	$32,949,000	+38.8%	123,848	+28.0%	2.09%	+3.3%
CNC	Buy	CENTENE CORP DEL	$31,565,000	+56.9%	218,021	+33.6%	2.00%	+16.7%
BDX	Buy	BECTON DICKINSON & CO	$27,513,000	+41.4%	105,413	+29.8%	1.74%	+5.2%
DHR	Buy	DANAHER CORP DEL	$27,493,000	+27.5%	253,016	+15.8%	1.74%	-5.1%
ALXN	Buy	ALEXION PHARMACEUTICALS INC	$25,450,000	+25.2%	183,080	+11.8%	1.61%	-6.9%
SYK	Buy	STRYKER CORP	$25,120,000	+25.2%	141,380	+19.0%	1.59%	-6.8%
BMY	Buy	BRISTOL MYERS SQUIBB CO	$21,215,000	+47.0%	341,729	+31.0%	1.35%	+9.3%
MYL	Buy	MYLAN N V	$20,692,000	+14.0%	565,350	+12.5%	1.31%	-15.2%
BAX	Buy	BAXTER INTL INC	$20,301,000	+30.9%	263,348	+25.4%	1.29%	-2.6%
SUPN	Buy	SUPERNUS PHARMACEUTICALS INC	$19,460,000	-0.4%	386,500	+18.3%	1.23%	-25.9%
ALNY	Buy	ALNYLAM PHARMACEUTICALS INC	$19,245,000	+88.8%	219,891	+112.5%	1.22%	+40.5%
PRAH	Buy	PRA HEALTH SCIENCES INC	$18,336,000	+51.8%	166,400	+28.6%	1.16%	+12.9%
WMGI	Buy	WRIGHT MED GROUP NV	$18,071,000	+22.1%	622,692	+9.2%	1.15%	-9.2%
HRC	Buy	HILL ROM HLDGS INC	$17,529,000	+11.7%	185,689	+3.3%	1.11%	-16.9%
ESPR	Buy	ESPERION THERAPEUTICS INC NEW	$17,386,000	+41.5%	391,852	+25.0%	1.10%	+5.3%
LH	Buy	LABORATORY CORP AMER HLDGS	$16,333,000	+20.9%	94,040	+25.0%	1.04%	-10.1%
IONS	Sell	IONIS PHARMACEUTICALS INC	$16,017,000	+19.2%	310,536	-3.7%	1.02%	-11.3%
MGNX	Buy	MACROGENICS INC	$15,529,000	+26.0%	724,302	+21.3%	0.98%	-6.3%
KTWO	Sell	K2M GROUP HLDGS INC	$15,110,000	+9.6%	552,054	-9.9%	0.96%	-18.5%
ALDR	Buy	ALDER BIOPHARMACEUTICALS INC	$15,072,000	+25.7%	905,254	+19.3%	0.96%	-6.5%
ABMD	Buy	ABIOMED INC	$14,902,000	+34.5%	33,135	+22.4%	0.94%	+0.1%
AKCA	Buy	AKCEA THERAPEUTICS INC	$14,656,000	+63.0%	418,496	+10.3%	0.93%	+21.3%
LIVN	Buy	LIVANOVA PLC	$14,435,000	+31.6%	116,443	+5.9%	0.92%	-2.0%
PACB	New	PACIFIC BIOSCIENCES OF CALIF INC	$13,931,000	–	2,575,000	–	0.88%	–
BIIB	Sell	BIOGEN INC	$13,866,000	+21.4%	39,245	-0.3%	0.88%	-9.6%
FIT	Buy	FITBIT INCcl a	$13,449,000	+0.1%	2,513,900	+22.2%	0.85%	-25.6%
HCM	Buy	HUTCHISON CHINA MEDITECH LTDsponsored adr	$12,877,000	+28.5%	400,029	+20.3%	0.82%	-4.3%
ZBH	Buy	ZIMMER BIOMET HLDGS INC	$12,109,000	+52.2%	92,104	+29.0%	0.77%	+13.3%
SHPG	Sell	SHIRE PLCsponsored adr	$11,635,000	+5.6%	64,185	-1.7%	0.74%	-21.5%
INSM	Buy	INSMED INC	$11,451,000	+14.2%	566,301	+33.5%	0.73%	-15.1%
RMD	Buy	RESMED INC	$10,749,000	+26.3%	93,192	+13.4%	0.68%	-6.1%
GILD	Sell	GILEAD SCIENCES INC	$10,616,000	-6.5%	137,500	-14.2%	0.67%	-30.5%
REGN	Buy	REGENERON PHARMACEUTICALS	$10,295,000	+72.9%	25,480	+47.6%	0.65%	+28.5%
DXCM	Sell	DEXCOM INC	$10,248,000	-60.2%	71,647	-73.6%	0.65%	-70.4%
GNMK	Buy	GENMARK DIAGNOSTICS INC	$9,845,000	+30.1%	1,339,502	+12.9%	0.62%	-3.1%
CDNA	New	CAREDX INC	$9,724,000	–	337,049	–	0.62%	–
IART	Buy	INTEGRA LIFESCIENCES HLDGS C	$9,329,000	+149.0%	141,620	+143.5%	0.59%	+85.6%
WCG	Buy	WELLCARE HEALTH PLANS INC	$9,060,000	+66.9%	28,269	+28.2%	0.58%	+24.2%
GMED	Buy	GLOBUS MED INCcl a	$8,585,000	+129.8%	151,251	+104.3%	0.54%	+70.8%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$8,414,000	+39.4%	34,471	+18.3%	0.53%	+3.9%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$7,805,000	+8.6%	40,494	-4.3%	0.50%	-19.2%
AMGN	Sell	AMGEN INC	$7,659,000	-13.4%	36,950	-22.9%	0.49%	-35.5%
OMCL	Buy	OMNICELL INC	$7,524,000	+124.3%	104,650	+63.7%	0.48%	+66.8%
MOH	Sell	MOLINA HEALTHCARE INC	$7,506,000	+46.7%	50,478	-3.4%	0.48%	+9.2%
HMSY	Buy	HMS HLDGS CORP	$7,449,000	+135.9%	227,020	+55.4%	0.47%	+75.8%
TRHC	Buy	TABULA RASA HEALTHCARE INC	$7,054,000	+64.2%	86,884	+29.1%	0.45%	+22.1%
XENT	Buy	INTERSECT ENT INC	$6,734,000	+104.2%	234,227	+166.1%	0.43%	+52.0%
QTRX	Buy	QUANTERIX CORP	$6,709,000	+182.4%	313,230	+89.3%	0.43%	+109.9%
IRTC	Buy	IRHYTHM TECHNOLOGIES INC	$6,594,000	+77.0%	69,661	+51.7%	0.42%	+31.4%
COO	Buy	COOPER COS INC	$6,322,000	+39.1%	22,811	+18.2%	0.40%	+3.6%
IDXX	Buy	IDEXX LABS INC	$6,068,000	+297.6%	24,307	+247.2%	0.38%	+196.2%
INGN	Buy	INOGEN INC	$5,678,000	+407.0%	23,261	+287.0%	0.36%	+278.9%
QTNT	Buy	QUOTIENT LTD	$5,450,000	+112.2%	721,858	+125.7%	0.35%	+58.0%
HCA	Buy	HCA HEALTHCARE INC	$5,132,000	+163.3%	36,888	+94.1%	0.33%	+96.4%
NBIX	Sell	NEUROCRINE BIOSCIENCES INC	$5,109,000	+19.4%	41,550	-4.6%	0.32%	-11.2%
QGEN	Buy	QIAGEN NV	$5,083,000	+83.0%	134,189	+74.6%	0.32%	+35.9%
TFX	Buy	TELEFLEX INC	$4,734,000	+26.1%	17,792	+27.1%	0.30%	-6.2%
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$4,642,000	-0.5%	47,869	-3.3%	0.29%	-26.1%
NVRO	Buy	NEVRO CORP	$4,584,000	+122.5%	80,415	+211.7%	0.29%	+65.3%
HZNP	Buy	HORIZON PHARMA PLC	$4,340,000	+36.8%	221,678	+15.7%	0.28%	+1.5%
XRAY	Buy	DENTSPLY SIRONA INC	$4,185,000	+27.3%	110,878	+47.7%	0.26%	-5.4%
TNDM	Sell	TANDEM DIABETES CARE INC	$4,164,000	+65.9%	97,195	-14.7%	0.26%	+23.4%
CERN	Buy	CERNER CORP	$3,810,000	+10.1%	59,146	+2.2%	0.24%	-18.0%
INSP	Buy	INSPIRE MED SYS INC	$3,816,000	+123.2%	90,696	+89.1%	0.24%	+65.8%
ENDP	Buy	ENDO INTL PLC	$3,659,000	+291.8%	217,392	+119.4%	0.23%	+190.0%
SGEN	Sell	SEATTLE GENETICS INC	$3,621,000	+10.2%	46,950	-5.2%	0.23%	-17.9%
INCY	Sell	INCYTE CORP	$3,616,000	-1.6%	52,350	-4.6%	0.23%	-26.8%
STIM	Buy	NEURONETICS INC	$3,588,000	+171.8%	111,907	+123.8%	0.23%	+101.8%
OXFD	Buy	OXFORD IMMUNOTEC GLOBAL PLC	$3,600,000	+152.5%	221,837	+100.5%	0.23%	+86.9%
VEEV	Buy	VEEVA SYS INC	$3,559,000	+349.9%	32,691	+217.5%	0.23%	+237.3%
CHRS	Buy	COHERUS BIOSCIENCES INC	$3,563,000	+28.6%	215,935	+9.1%	0.23%	-4.2%
IBB	New	ISHARES TRnasdaq biotech	$3,414,000	–	28,000	–	0.22%	–
NKTR	Buy	NEKTAR THERAPEUTICS	$3,384,000	+100.8%	55,520	+60.9%	0.22%	+49.3%
AMED	New	AMEDISYS INC	$3,149,000	–	25,204	–	0.20%	–
LGND	Sell	LIGAND PHARMACEUTICALS INC	$3,094,000	+23.7%	11,270	-6.6%	0.20%	-8.0%
ICPT	Sell	INTERCEPT PHARMACEUTICALS IN	$3,051,000	+47.5%	24,148	-2.0%	0.19%	+10.2%
MTLS	Buy	MATERIALISE NVsponsored ads	$2,908,000	+470.2%	210,731	+435.8%	0.18%	+327.9%
PEN	Buy	PENUMBRA INC	$2,866,000	+47.9%	19,142	+36.5%	0.18%	+10.3%
MDSO	Buy	MEDIDATA SOLUTIONS INC	$2,706,000	+621.6%	36,907	+693.9%	0.17%	+437.5%
AGN	Buy	ALLERGAN PLC	$2,476,000	+48.5%	13,000	+30.0%	0.16%	+10.6%
RARE	Sell	ULTRAGENYX PHARMACEUTICAL INC	$2,431,000	-19.2%	31,850	-18.6%	0.15%	-40.1%
MASI	Buy	MASIMO CORP	$2,426,000	+67.9%	19,476	+31.6%	0.15%	+25.2%
CSLT	Buy	CASTLIGHT HEALTH INCcl b	$2,400,000	+96.6%	888,842	+209.3%	0.15%	+46.2%
AMRX	Buy	AMNEAL PHARMACEUTICALS INC	$2,108,000	+71.2%	95,000	+26.7%	0.13%	+27.6%
SRPT	New	SAREPTA THERAPEUTICS INC	$2,116,000	–	13,100	–	0.13%	–
BGNE	Buy	BEIGENE LTDsponsored adr	$2,001,000	+13.2%	11,620	+1.0%	0.13%	-15.9%
RGNX	Sell	REGENXBIO INC	$1,759,000	+3.0%	23,300	-2.1%	0.11%	-23.3%
BLUE	Sell	BLUEBIRD BIO INC	$1,664,000	-17.8%	11,400	-11.6%	0.11%	-38.7%
SAGE	Sell	SAGE THERAPEUTICS INC	$1,582,000	-16.5%	11,200	-7.4%	0.10%	-37.9%
AGIO	Sell	AGIOS PHARMACEUTICALS INC	$1,532,000	-36.9%	19,861	-31.1%	0.10%	-53.1%
TSRO	Buy	TESARO INC	$1,504,000	+33.9%	38,550	+52.7%	0.10%	-1.0%
IRWD	New	IRONWOOD PHARMACEUTICALS INC	$1,466,000	–	79,400	–	0.09%	–
ARNA	Sell	ARENA PHARMACEUTICALS INC	$1,418,000	+3.5%	30,817	-1.9%	0.09%	-23.1%
CLLS	Sell	CELLECTIS S Asponsored ads	$1,400,000	-2.2%	49,600	-2.0%	0.09%	-27.0%
SYNH	Sell	SYNEOS HEALTH INCcl a	$1,348,000	+7.8%	26,156	-1.9%	0.09%	-19.6%
TEVA	Sell	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$1,292,000	-41.0%	60,000	-33.3%	0.08%	-56.1%
EGRX	Sell	EAGLE PHARMACEUTICALS INC	$1,248,000	-50.0%	18,000	-45.5%	0.08%	-62.9%
ACAD	New	ACADIA PHARMACEUTICALS INC	$1,183,000	–	57,000	–	0.08%	–
ITCI	Sell	INTRA CELLULAR THERAPIES INC	$1,185,000	-16.1%	54,600	-31.7%	0.08%	-37.5%
MRTX	Sell	MIRATI THERAPEUTICS INC	$1,178,000	-6.3%	25,000	-2.0%	0.08%	-29.9%
GWPH	Sell	GW PHARMACEUTICALS PLCads	$1,145,000	+14.3%	6,629	-7.7%	0.07%	-14.1%
MCK	Sell	MCKESSON CORP	$1,128,000	-28.7%	8,503	-28.2%	0.07%	-46.7%
PTCT	New	PTC THERAPEUTICS INC	$1,058,000	–	22,500	–	0.07%	–
XLRN	New	ACCELERON PHARMA INC	$927,000	–	16,200	–	0.06%	–
VYGR	Buy	VOYAGER THERAPEUTICS INC	$822,000	+148.3%	43,422	+156.6%	0.05%	+85.7%
ADAP	Sell	ADAPTIMMUNE THERAPEUTICS PLCsponds adr	$794,000	+11.7%	58,535	-2.3%	0.05%	-18.0%
QURE	Sell	UNIQURE NV	$724,000	-5.2%	19,900	-1.5%	0.05%	-29.2%
PTLA	Sell	PORTOLA PHARMACEUTICALS INC	$710,000	-54.7%	26,650	-35.8%	0.04%	-66.4%
PINC	New	PREMIER INCcl a	$691,000	–	15,100	–	0.04%	–
NTLA	Sell	INTELLIA THERAPEUTICS INC	$470,000	+2.6%	16,434	-1.8%	0.03%	-23.1%
IOVA	New	IOVANCE BIOTHERAPEUTICS INC	$281,000	–	25,000	–	0.02%	–
EARS	Exit	AURIS MED HLDG AG	$0	–	-193,125	–	-0.01%	–
AACH	Exit	AAC HLDGS INC	$0	–	-39,000	–	-0.03%	–
MDCO	Exit	MEDICINES CO	$0	–	-17,050	–	-0.05%	–
BLCM	Exit	BELLICUM PHARMACEUTICALS INC	$0	–	-90,020	–	-0.06%	–
CLVS	Exit	CLOVIS ONCOLOGY INC	$0	–	-17,250	–	-0.07%	–
CAH	Exit	CARDINAL HEALTH INC	$0	–	-18,000	–	-0.08%	–
COTV	Exit	COTIVITI HLDGS INC	$0	–	-24,774	–	-0.09%	–
FMI	Exit	FOUNDATION MEDICINE INC	$0	–	-8,357	–	-0.10%	–
ALKS	Exit	ALKERMES PLC	$0	–	-32,650	–	-0.12%	–
DVAX	Exit	DYNAVAX TECHNOLOGIES CORP	$0	–	-91,800	–	-0.12%	–
VRX	Exit	VALEANT PHARMACEUTICALS INTL	$0	–	-130,000	–	-0.26%	–

Q2 2018

			Value		Shares		↓ Weighting
ANTM	New	ANTHEM INC	$50,826,000	–	213,527	–	4.33%	–
ALGN	New	ALIGN TECHNOLOGY INC	$44,840,000	–	131,058	–	3.82%	–
CELG	New	CELGENE CORP	$42,315,000	–	532,800	–	3.61%	–
ISRG	New	INTUITIVE SURGICAL INC	$41,981,000	–	87,739	–	3.58%	–
ILMN	New	ILLUMINA INC	$39,372,000	–	140,971	–	3.36%	–
ABT	New	ABBOTT LABS	$34,694,000	–	568,850	–	2.96%	–
MDT	New	MEDTRONIC PLC	$34,405,000	–	401,881	–	2.93%	–
TDOC	New	TELADOC INC	$33,095,000	–	570,110	–	2.82%	–
EW	New	EDWARDS LIFESCIENCES CORP	$29,938,000	–	205,660	–	2.55%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$28,418,000	–	164,933	–	2.42%	–
BSX	New	BOSTON SCIENTIFIC CORP	$26,833,000	–	820,596	–	2.29%	–
HUM	New	HUMANA INC	$25,849,000	–	86,850	–	2.20%	–
DXCM	New	DEXCOM INC	$25,730,000	–	270,897	–	2.19%	–
UNH	New	UNITEDHEALTH GROUP INC	$23,731,000	–	96,729	–	2.02%	–
DHR	New	DANAHER CORP DEL	$21,558,000	–	218,465	–	1.84%	–
CI	New	CIGNA CORPORATION	$21,453,000	–	126,234	–	1.83%	–
ABC	New	AMERISOURCEBERGEN CORP	$20,367,000	–	238,853	–	1.74%	–
ALXN	New	ALEXION PHARMACEUTICALS INC	$20,327,000	–	163,730	–	1.73%	–
CNC	New	CENTENE CORP DEL	$20,114,000	–	163,247	–	1.72%	–
SYK	New	STRYKER CORP	$20,056,000	–	118,770	–	1.71%	–
SUPN	New	SUPERNUS PHARMACEUTICALS INC	$19,547,000	–	326,600	–	1.67%	–
BDX	New	BECTON DICKINSON & CO	$19,456,000	–	81,215	–	1.66%	–
MYL	New	MYLAN N V	$18,155,000	–	502,350	–	1.55%	–
HRC	New	HILL ROM HLDGS INC	$15,694,000	–	179,689	–	1.34%	–
BAX	New	BAXTER INTL INC	$15,506,000	–	210,000	–	1.32%	–
WMGI	New	WRIGHT MED GROUP NV	$14,805,000	–	570,301	–	1.26%	–
BMY	New	BRISTOL MYERS SQUIBB CO	$14,435,000	–	260,849	–	1.23%	–
HOLX	New	HOLOGIC INC	$14,385,000	–	361,894	–	1.23%	–
KTWO	New	K2M GROUP HLDGS INC	$13,791,000	–	612,941	–	1.18%	–
WBA	New	WALGREENS BOOTS ALLIANCE INC	$13,564,000	–	226,018	–	1.16%	–
LH	New	LABORATORY CORP AMER HLDGS	$13,508,000	–	75,240	–	1.15%	–
FIT	New	FITBIT INCcl a	$13,438,000	–	2,057,900	–	1.15%	–
IONS	New	IONIS PHARMACEUTICALS INC	$13,442,000	–	322,586	–	1.15%	–
MGNX	New	MACROGENICS INC	$12,326,000	–	596,913	–	1.05%	–
ESPR	New	ESPERION THERAPEUTICS INC NEW	$12,287,000	–	313,520	–	1.05%	–
PRAH	New	PRA HEALTH SCIENCES INC	$12,081,000	–	129,400	–	1.03%	–
ALDR	New	ALDER BIOPHARMACEUTICALS INC	$11,992,000	–	758,964	–	1.02%	–
BIIB	New	BIOGEN INC	$11,419,000	–	39,345	–	0.97%	–
GILD	New	GILEAD SCIENCES INC	$11,356,000	–	160,300	–	0.97%	–
ABMD	New	ABIOMED INC	$11,077,000	–	27,081	–	0.94%	–
SHPG	New	SHIRE PLCsponsored adr	$11,021,000	–	65,292	–	0.94%	–
LIVN	New	LIVANOVA PLC	$10,973,000	–	109,924	–	0.94%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$10,194,000	–	103,500	–	0.87%	–
INSM	New	INSMED INC	$10,029,000	–	424,051	–	0.86%	–
HCM	New	HUTCHISON CHINA MEDITECH LTDsponsored adr	$10,023,000	–	332,536	–	0.85%	–
AKCA	New	AKCEA THERAPEUTICS INC	$8,993,000	–	379,301	–	0.77%	–
AMGN	New	AMGEN INC	$8,842,000	–	47,900	–	0.75%	–
RMD	New	RESMED INC	$8,514,000	–	82,200	–	0.73%	–
ZBH	New	ZIMMER BIOMET HLDGS INC	$7,957,000	–	71,401	–	0.68%	–
GNMK	New	GENMARK DIAGNOSTICS INC	$7,570,000	–	1,186,502	–	0.64%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$7,188,000	–	42,294	–	0.61%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$6,034,000	–	29,131	–	0.51%	–
REGN	New	REGENERON PHARMACEUTICALS	$5,955,000	–	17,260	–	0.51%	–
WCG	New	WELLCARE HEALTH PLANS INC	$5,430,000	–	22,050	–	0.46%	–
MOH	New	MOLINA HEALTHCARE INC	$5,116,000	–	52,240	–	0.44%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$4,665,000	–	49,519	–	0.40%	–
COO	New	COOPER COS INC	$4,544,000	–	19,300	–	0.39%	–
TRHC	New	TABULA RASA HEALTHCARE INC	$4,296,000	–	67,306	–	0.37%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$4,278,000	–	43,550	–	0.36%	–
TFX	New	TELEFLEX INC	$3,755,000	–	14,000	–	0.32%	–
IART	New	INTEGRA LIFESCIENCES HLDGS C	$3,746,000	–	58,161	–	0.32%	–
GMED	New	GLOBUS MED INCcl a	$3,736,000	–	74,045	–	0.32%	–
HSIC	New	SCHEIN HENRY INC	$3,731,000	–	51,368	–	0.32%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$3,726,000	–	45,921	–	0.32%	–
INCY	New	INCYTE CORP	$3,675,000	–	54,850	–	0.31%	–
CERN	New	CERNER CORP	$3,462,000	–	57,900	–	0.30%	–
ESRX	New	EXPRESS SCRIPTS HLDG CO	$3,436,000	–	44,500	–	0.29%	–
OMCL	New	OMNICELL INC	$3,354,000	–	63,945	–	0.29%	–
XENT	New	INTERSECT ENT INC	$3,297,000	–	88,028	–	0.28%	–
XRAY	New	DENTSPLY SIRONA INC	$3,287,000	–	75,093	–	0.28%	–
SGEN	New	SEATTLE GENETICS INC	$3,286,000	–	49,500	–	0.28%	–
HZNP	New	HORIZON PHARMA PLC	$3,173,000	–	191,578	–	0.27%	–
HMSY	New	HMS HLDGS CORP	$3,158,000	–	146,069	–	0.27%	–
VRX	New	VALEANT PHARMACEUTICALS INTL	$3,021,000	–	130,000	–	0.26%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL INC	$3,009,000	–	39,150	–	0.26%	–
QGEN	New	QIAGEN NV	$2,778,000	–	76,838	–	0.24%	–
CHRS	New	COHERUS BIOSCIENCES INC	$2,770,000	–	197,835	–	0.24%	–
QTNT	New	QUOTIENT LTD	$2,568,000	–	319,814	–	0.22%	–
TNDM	New	TANDEM DIABETES CARE INC	$2,510,000	–	114,006	–	0.21%	–
EGRX	New	EAGLE PHARMACEUTICALS INC	$2,497,000	–	33,000	–	0.21%	–
LGND	New	LIGAND PHARMACEUTICALS INC	$2,501,000	–	12,070	–	0.21%	–
JNJ	New	JOHNSON & JOHNSON	$2,427,000	–	20,000	–	0.21%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$2,427,000	–	28,811	–	0.21%	–
QTRX	New	QUANTERIX CORP	$2,376,000	–	165,480	–	0.20%	–
TEVA	New	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$2,189,000	–	90,000	–	0.19%	–
ICPT	New	INTERCEPT PHARMACEUTICALS IN	$2,068,000	–	24,648	–	0.18%	–
NVRO	New	NEVRO CORP	$2,060,000	–	25,798	–	0.18%	–
BLUE	New	BLUEBIRD BIO INC	$2,025,000	–	12,900	–	0.17%	–
HCA	New	HCA HEALTHCARE INC	$1,949,000	–	19,000	–	0.17%	–
PEN	New	PENUMBRA INC	$1,938,000	–	14,027	–	0.16%	–
SAGE	New	SAGE THERAPEUTICS INC	$1,894,000	–	12,100	–	0.16%	–
BGNE	New	BEIGENE LTDsponsored adr	$1,768,000	–	11,500	–	0.15%	–
INSP	New	INSPIRE MED SYS INC	$1,710,000	–	47,953	–	0.15%	–
RGNX	New	REGENXBIO INC	$1,708,000	–	23,800	–	0.15%	–
ANGO	New	ANGIODYNAMICS INC	$1,684,000	–	75,700	–	0.14%	–
NKTR	New	NEKTAR THERAPEUTICS	$1,685,000	–	34,500	–	0.14%	–
AGN	New	ALLERGAN PLC	$1,667,000	–	10,000	–	0.14%	–
MCK	New	MCKESSON CORP	$1,581,000	–	11,850	–	0.14%	–
PTLA	New	PORTOLA PHARMACEUTICALS INC	$1,567,000	–	41,500	–	0.13%	–
PODD	New	INSULET CORP	$1,543,000	–	18,000	–	0.13%	–
IDXX	New	IDEXX LABS INC	$1,526,000	–	7,000	–	0.13%	–
MASI	New	MASIMO CORP	$1,445,000	–	14,800	–	0.12%	–
OXFD	New	OXFORD IMMUNOTEC GLOBAL PLC	$1,426,000	–	110,661	–	0.12%	–
CLLS	New	CELLECTIS S Asponsored ads	$1,431,000	–	50,600	–	0.12%	–
ITCI	New	INTRA CELLULAR THERAPIES INC	$1,412,000	–	79,900	–	0.12%	–
DVAX	New	DYNAVAX TECHNOLOGIES CORP	$1,400,000	–	91,800	–	0.12%	–
ARNA	New	ARENA PHARMACEUTICALS INC	$1,370,000	–	31,417	–	0.12%	–
ALKS	New	ALKERMES PLC	$1,344,000	–	32,650	–	0.12%	–
STIM	New	NEURONETICS INC	$1,320,000	–	50,000	–	0.11%	–
AET	New	AETNA INC NEW	$1,303,000	–	7,100	–	0.11%	–
SYNH	New	SYNEOS HEALTH INCcl a	$1,250,000	–	26,656	–	0.11%	–
MRTX	New	MIRATI THERAPEUTICS INC	$1,257,000	–	25,500	–	0.11%	–
AMRX	New	AMNEAL PHARMACEUTICALS INC	$1,231,000	–	75,000	–	0.10%	–
CSLT	New	CASTLIGHT HEALTH INCcl b	$1,221,000	–	287,340	–	0.10%	–
FMI	New	FOUNDATION MEDICINE INC	$1,142,000	–	8,357	–	0.10%	–
TSRO	New	TESARO INC	$1,123,000	–	25,250	–	0.10%	–
INGN	New	INOGEN INC	$1,120,000	–	6,011	–	0.10%	–
COTV	New	COTIVITI HLDGS INC	$1,093,000	–	24,774	–	0.09%	–
PFE	New	PFIZER INC	$1,059,000	–	29,200	–	0.09%	–
GWPH	New	GW PHARMACEUTICALS PLCads	$1,002,000	–	7,179	–	0.08%	–
ENDP	New	ENDO INTL PLC	$934,000	–	99,092	–	0.08%	–
CAH	New	CARDINAL HEALTH INC	$879,000	–	18,000	–	0.08%	–
VEEV	New	VEEVA SYS INC	$791,000	–	10,296	–	0.07%	–
CLVS	New	CLOVIS ONCOLOGY INC	$784,000	–	17,250	–	0.07%	–
MRK	New	MERCK & CO INC	$759,000	–	12,500	–	0.06%	–
QURE	New	UNIQURE NV	$764,000	–	20,200	–	0.06%	–
ADAP	New	ADAPTIMMUNE THERAPEUTICS PLCsponds adr	$711,000	–	59,935	–	0.06%	–
VAR	New	VARIAN MED SYS INC	$716,000	–	6,300	–	0.06%	–
BLCM	New	BELLICUM PHARMACEUTICALS INC	$664,000	–	90,020	–	0.06%	–
HCSG	New	HEALTHCARE SVCS GRP INC	$648,000	–	15,000	–	0.06%	–
MDCO	New	MEDICINES CO	$626,000	–	17,050	–	0.05%	–
CVS	New	CVS HEALTH CORP	$515,000	–	8,000	–	0.04%	–
MTLS	New	MATERIALISE NVsponsored ads	$510,000	–	39,329	–	0.04%	–
NTLA	New	INTELLIA THERAPEUTICS INC	$458,000	–	16,734	–	0.04%	–
MDSO	New	MEDIDATA SOLUTIONS INC	$375,000	–	4,649	–	0.03%	–
AACH	New	AAC HLDGS INC	$365,000	–	39,000	–	0.03%	–
VYGR	New	VOYAGER THERAPEUTICS INC	$331,000	–	16,922	–	0.03%	–
EARS	New	AURIS MED HLDG AG	$151,000	–	193,125	–	0.01%	–

Q4 2017

			Value		Shares		↓ Weighting
SGRY	Exit	SURGERY PARTNERS INC	$0	–	-31,000	–	-0.03%	–
ALDR	Exit	ALDER BIOPHARMACEUTICALS INC	$0	–	-33,000	–	-0.04%	–
ESPR	Exit	ESPERION THERAPEUTICS INC NEW	$0	–	-8,000	–	-0.04%	–
AACH	Exit	AAC HLDGS INC	$0	–	-45,000	–	-0.05%	–
CLDX	Exit	CELLDEX THERAPEUTICS INC NEW	$0	–	-160,000	–	-0.05%	–
OBLN	Exit	OBALON THERAPEUTICS INC	$0	–	-48,000	–	-0.05%	–
MYGN	Exit	MYRIAD GENETICS INC	$0	–	-13,000	–	-0.05%	–
TBPH	Exit	THERAVANCE BIOPHARMA INC	$0	–	-14,428	–	-0.05%	–
ICPT	Exit	INTERCEPT PHARMACEUTICALS IN	$0	–	-8,500	–	-0.05%	–
ADMS	Exit	ADAMAS PHARMACEUTICALS INC	$0	–	-24,000	–	-0.05%	–
CEMP	Exit	CEMPRA INC	$0	–	-165,000	–	-0.06%	–
QTNT	Exit	QUOTIENT LTD	$0	–	-110,000	–	-0.06%	–
EVHC	Exit	ENVISION HEALTHCARE CORP	$0	–	-13,026	–	-0.06%	–
GWPH	Exit	GW PHARMACEUTICALS PLCads	$0	–	-6,000	–	-0.06%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-40,000	–	-0.07%	–
VAR	Exit	VARIAN MED SYS INC	$0	–	-7,000	–	-0.07%	–
CVS	Exit	CVS HEALTH CORP	$0	–	-8,800	–	-0.08%	–
MDCO	Exit	MEDICINES CO	$0	–	-19,500	–	-0.08%	–
COTV	Exit	COTIVITI HLDGS INC	$0	–	-21,708	–	-0.08%	–
INO	Exit	INOVIO PHARMACEUTICALS INC	$0	–	-144,000	–	-0.10%	–
NVRO	Exit	NEVRO CORP	$0	–	-10,700	–	-0.10%	–
ENDP	Exit	ENDO INTL PLC	$0	–	-115,000	–	-0.10%	–
GKOS	Exit	GLAUKOS CORP	$0	–	-30,000	–	-0.10%	–
PODD	Exit	INSULET CORP	$0	–	-18,000	–	-0.10%	–
PFE	Exit	PFIZER INC	$0	–	-29,200	–	-0.11%	–
HMSY	Exit	HMS HLDGS CORP	$0	–	-53,500	–	-0.11%	–
EXEL	Exit	EXELIXIS INC	$0	–	-52,000	–	-0.13%	–
DVAX	Exit	DYNAVAX TECHNOLOGIES CORP	$0	–	-59,500	–	-0.13%	–
XENT	Exit	INTERSECT ENT INC	$0	–	-41,000	–	-0.13%	–
BIVV	Exit	BIOVERATIV INC	$0	–	-22,750	–	-0.14%	–
CAH	Exit	CARDINAL HEALTH INC	$0	–	-20,000	–	-0.14%	–
RDUS	Exit	RADIUS HEALTH INC	$0	–	-36,500	–	-0.15%	–
TSRO	Exit	TESARO INC	$0	–	-11,000	–	-0.15%	–
MASI	Exit	MASIMO CORP	$0	–	-17,000	–	-0.15%	–
TRHC	Exit	TABULA RASA HEALTHCARE INC	$0	–	-55,407	–	-0.16%	–
ACHC	Exit	ACADIA HEALTHCARE COMPANY IN	$0	–	-31,000	–	-0.16%	–
PEN	Exit	PENUMBRA INC	$0	–	-16,800	–	-0.16%	–
CLVS	Exit	CLOVIS ONCOLOGY INC	$0	–	-18,500	–	-0.16%	–
HALO	Exit	HALOZYME THERAPEUTICS INC	$0	–	-87,600	–	-0.16%	–
TDOC	Exit	TELADOC INC	$0	–	-47,000	–	-0.16%	–
GMED	Exit	GLOBUS MED INCcl a	$0	–	-55,000	–	-0.17%	–
HCA	Exit	HCA HEALTHCARE INC	$0	–	-21,300	–	-0.18%	–
PTLA	Exit	PORTOLA PHARMACEUTICALS INC	$0	–	-31,500	–	-0.18%	–
IRTC	Exit	IRHYTHM TECHNOLOGIES INC	$0	–	-33,400	–	-0.18%	–
ANGO	Exit	ANGIODYNAMICS INC	$0	–	-101,700	–	-0.18%	–
HCM	Exit	HUTCHISON CHINA MEDTECH LTDsponsored adr	$0	–	-64,573	–	-0.18%	–
MRK	Exit	MERCK & CO INC	$0	–	-27,500	–	-0.18%	–
IPXL	Exit	IMPAX LABORATORIES INC	$0	–	-87,000	–	-0.18%	–
EARS	Exit	AURIS MED HLDG AG	$0	–	-2,169,625	–	-0.19%	–
JUNO	Exit	JUNO THERAPEUTICS INC	$0	–	-43,000	–	-0.20%	–
QGEN	Exit	QIAGEN NV	$0	–	-61,611	–	-0.20%	–
HCSG	Exit	HEALTHCARE SVCS GRP INC	$0	–	-38,000	–	-0.22%	–
DXCM	Exit	DEXCOM INC	$0	–	-45,000	–	-0.23%	–
RARE	Exit	ULTRAGENYX PHARMACEUTICAL INC	$0	–	-42,000	–	-0.23%	–
PRTA	Exit	PROTHENA CORP PLC	$0	–	-37,400	–	-0.25%	–
SGEN	Exit	SEATTLE GENETICS INC	$0	–	-45,000	–	-0.26%	–
TFX	Exit	TELEFLEX INC	$0	–	-10,200	–	-0.26%	–
UTHR	Exit	UNITED THERAPEUTICS CORP DEL	$0	–	-21,600	–	-0.26%	–
NUVA	Exit	NUVASIVE INC	$0	–	-46,204	–	-0.27%	–
MCK	Exit	MCKESSON CORP	$0	–	-18,000	–	-0.29%	–
ALKS	Exit	ALKERMES PLC	$0	–	-56,100	–	-0.30%	–
NKTR	Exit	NEKTAR THERAPEUTICS	$0	–	-123,000	–	-0.31%	–
MOH	Exit	MOLINA HEALTHCARE INC	$0	–	-43,500	–	-0.31%	–
IBB	Exit	ISHARES TRnasdq biotec etf	$0	–	-9,000	–	-0.31%	–
AGIO	Exit	AGIOS PHARMACEUTICALS INC	$0	–	-45,000	–	-0.31%	–
HSIC	Exit	SCHEIN HENRY INC	$0	–	-38,000	–	-0.33%	–
ESRX	Exit	EXPRESS SCRIPTS HLDG CO	$0	–	-49,500	–	-0.33%	–
XRAY	Exit	DENTSPLY SIRONA INC	$0	–	-54,500	–	-0.34%	–
NBIX	Exit	NEUROCRINE BIOSCIENCES INC	$0	–	-56,000	–	-0.36%	–
BLUE	Exit	BLUEBIRD BIO INC	$0	–	-25,100	–	-0.36%	–
RMD	Exit	RESMED INC	$0	–	-47,000	–	-0.38%	–
PRGO	Exit	PERRIGO CO PLC	$0	–	-46,468	–	-0.41%	–
JNJ	Exit	JOHNSON & JOHNSON	$0	–	-31,500	–	-0.43%	–
AGN	Exit	ALLERGAN PLC	$0	–	-20,500	–	-0.44%	–
ACAD	Exit	ACADIA PHARMACEUTICALS INC	$0	–	-117,000	–	-0.46%	–
BMRN	Exit	BIOMARIN PHARMACEUTICAL INC	$0	–	-48,800	–	-0.48%	–
EGRX	Exit	EAGLE PHARMACEUTICALS INC	$0	–	-81,550	–	-0.51%	–
TMO	Exit	THERMO FISHER SCIENTIFIC INC	$0	–	-25,808	–	-0.51%	–
GNMK	Exit	GENMARK DIAGNOSTICS INC	$0	–	-523,677	–	-0.53%	–
CERN	Exit	CERNER CORP	$0	–	-74,500	–	-0.56%	–
MYL	Exit	MYLAN N V	$0	–	-181,200	–	-0.59%	–
COO	Exit	COOPER COS INC	$0	–	-24,000	–	-0.60%	–
HZNP	Exit	HORIZON PHARMA PLC	$0	–	-486,463	–	-0.65%	–
SHPG	Exit	SHIRE PLCsponsored adr	$0	–	-42,440	–	-0.68%	–
LGND	Exit	LIGAND PHARAMCEUTICALS INC	$0	–	-48,700	–	-0.69%	–
Q	Exit	QUINTILES IMS HOLDING INC	$0	–	-71,170	–	-0.71%	–
BCR	Exit	BARD C R INC	$0	–	-22,740	–	-0.76%	–
HUM	Exit	HUMANA INC	$0	–	-31,350	–	-0.80%	–
MGNX	Exit	MACROGENICS INC	$0	–	-433,299	–	-0.84%	–
LH	Exit	LABORATORY CORP AMER HLDGS	$0	–	-54,680	–	-0.86%	–
MNKKQ	Exit	MALLINCKRODT PUB LTD CO	$0	–	-229,983	–	-0.90%	–
ALNY	Exit	ALNYLAM PHARMACEUTICALS INC	$0	–	-75,593	–	-0.93%	–
CI	Exit	CIGNA CORPORATION	$0	–	-47,650	–	-0.93%	–
IART	Exit	INTEGRA LIFESCIENCES HLDGS C	$0	–	-176,850	–	-0.93%	–
AET	Exit	AETNA INC NEW	$0	–	-56,700	–	-0.94%	–
VRTX	Exit	VERTEX PHARMACEUTICALS INC	$0	–	-59,800	–	-0.95%	–
ABBV	Exit	ABBVIE INC	$0	–	-102,777	–	-0.96%	–
THC	Exit	TENET HEALTHCARE CORP	$0	–	-616,796	–	-1.06%	–
TEVA	Exit	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$0	–	-581,940	–	-1.07%	–
BDX	Exit	BECTON DICKINSON & CO	$0	–	-55,000	–	-1.13%	–
ZBH	Exit	ZIMMER BIOMET HLDGS INC	$0	–	-93,000	–	-1.14%	–
LIVN	Exit	LIVANOVA PLC	$0	–	-158,069	–	-1.16%	–
CNC	Exit	CENTENE CORP DEL	$0	–	-118,930	–	-1.20%	–
SYK	Exit	STRYKER CORP	$0	–	-84,300	–	-1.25%	–
ALXN	Exit	ALEXION PHARMACEUTICALS INC	$0	–	-86,000	–	-1.26%	–
HRC	Exit	HILL ROM HLDGS INC	$0	–	-169,939	–	-1.32%	–
HOLX	Exit	HOLOGIC INC	$0	–	-363,101	–	-1.39%	–
IONS	Exit	IONIS PHARMACEUTICALS INC	$0	–	-265,706	–	-1.41%	–
REGN	Exit	REGENERON PHARMACEUTICALS	$0	–	-30,200	–	-1.41%	–
BAX	Exit	BAXTER INTL INC	$0	–	-216,000	–	-1.42%	–
DHR	Exit	DANAHER CORP DEL	$0	–	-158,800	–	-1.42%	–
WMGI	Exit	WRIGHT MED GROUP NV	$0	–	-541,801	–	-1.47%	–
ABMD	Exit	ABIOMED INC	$0	–	-85,110	–	-1.50%	–
ABC	Exit	AMERISOURCEBERGEN CORP	$0	–	-197,991	–	-1.71%	–
JAZZ	Exit	JAZZ PHARMACEUTICALS PLC	$0	–	-115,252	–	-1.76%	–
MDT	Exit	MEDTRONIC PLC	$0	–	-217,000	–	-1.76%	–
INCY	Exit	INCYTE CORP	$0	–	-146,366	–	-1.79%	–
BIIB	Exit	BIOGEN INC	$0	–	-58,900	–	-1.93%	–
WBA	Exit	WALGREENS BOOTS ALLIANCE INC	$0	–	-262,060	–	-2.12%	–
BSX	Exit	BOSTON SCIENTIFIC CORP	$0	–	-696,000	–	-2.12%	–
LLY	Exit	LILLY ELI & CO	$0	–	-241,262	–	-2.16%	–
EW	Exit	EDWARDS LIFESCIENCES CORP	$0	–	-205,860	–	-2.35%	–
UNH	Exit	UNITEDHEALTH GROUP INC	$0	–	-136,270	–	-2.79%	–
ABT	Exit	ABBOTT LABS	$0	–	-503,000	–	-2.81%	–
ISRG	Exit	INTUITIVE SURGICAL INC	$0	–	-30,377	–	-3.32%	–
ANTM	Exit	ANTHEM INC	$0	–	-171,143	–	-3.40%	–
ILMN	Exit	ILLUMINA INC	$0	–	-163,525	–	-3.41%	–
GILD	Exit	GILEAD SCIENCES INC	$0	–	-402,541	–	-3.41%	–
ALGN	Exit	ALIGN TECHNOLOGY INC	$0	–	-192,746	–	-3.75%	–
AMGN	Exit	AMGEN INC	$0	–	-198,645	–	-3.87%	–
CELG	Exit	CELGENE CORP	$0	–	-332,369	–	-5.07%	–

Q3 2017

			Value		Shares		↓ Weighting
CELG	Buy	CELGENE CORP	$48,461,000	+42.4%	332,369	+26.9%	5.07%	+26.0%
AMGN	Buy	AMGEN INC	$37,023,000	+31.3%	198,645	+21.3%	3.87%	+16.1%
ALGN	Buy	ALIGN TECHNOLOGY INC	$35,890,000	+75.5%	192,746	+41.5%	3.75%	+55.3%
GILD	Buy	GILEAD SCIENCES INC	$32,610,000	+47.8%	402,541	+29.1%	3.41%	+30.7%
ILMN	Buy	ILLUMINA INC	$32,570,000	+73.1%	163,525	+50.8%	3.41%	+53.1%
ANTM	Buy	ANTHEM INC	$32,490,000	+40.0%	171,143	+38.7%	3.40%	+23.8%
ISRG	Buy	INTUITIVE SURGICAL INC	$31,760,000	+43.2%	30,377	+28.1%	3.32%	+26.7%
ABT	Buy	ABBOTT LABS	$26,840,000	+24.6%	503,000	+13.5%	2.81%	+10.3%
UNH	Buy	UNITEDHEALTH GROUP INC	$26,688,000	+11.5%	136,270	+5.6%	2.79%	-1.3%
EW	Buy	EDWARDS LIFESCIENCES CORP	$22,503,000	+0.2%	205,860	+8.4%	2.35%	-11.3%
LLY	Buy	LILLY ELI & CO	$20,631,000	+38.4%	241,262	+33.2%	2.16%	+22.5%
BSX	Buy	BOSTON SCIENTIFIC CORP	$20,302,000	+16.6%	696,000	+10.8%	2.12%	+3.2%
WBA	Buy	WALGREENS BOOTS ALLIANCE INC	$20,224,000	+38.9%	262,060	+41.0%	2.12%	+22.9%
BIIB	Sell	BIOGEN INC	$18,443,000	+10.5%	58,900	-4.2%	1.93%	-2.2%
INCY	Buy	INCYTE CORP	$17,086,000	+10.0%	146,366	+18.6%	1.79%	-2.7%
MDT	Sell	MEDTRONIC PLC	$16,876,000	-37.8%	217,000	-29.0%	1.76%	-44.9%
JAZZ	Buy	JAZZ PHARMACEUTICALS PLC	$16,856,000	+8.2%	115,252	+15.0%	1.76%	-4.3%
ABC	Buy	AMERISOURCEBERGEN CORP	$16,384,000	+53.3%	197,991	+75.1%	1.71%	+35.6%
ABMD	Buy	ABIOMED INC	$14,350,000	+19.3%	85,110	+1.4%	1.50%	+5.5%
WMGI	Buy	WRIGHT MED GROUP NV	$14,016,000	+51.7%	541,801	+61.2%	1.47%	+34.2%
DHR	Buy	DANAHER CORP DEL	$13,622,000	+12.9%	158,800	+11.0%	1.42%	-0.1%
BAX	Buy	BAXTER INTL INC	$13,554,000	+8.7%	216,000	+4.9%	1.42%	-3.9%
REGN	Buy	REGENERON PHARMACEUTICALS	$13,503,000	-2.2%	30,200	+7.5%	1.41%	-13.5%
IONS	Buy	IONIS PHARMACEUTICALS INC	$13,469,000	+17.9%	265,706	+18.3%	1.41%	+4.3%
HOLX	Buy	HOLOGIC INC	$13,322,000	+7.4%	363,101	+32.8%	1.39%	-5.0%
HRC	Buy	HILL ROM HLDGS INC	$12,575,000	+51.2%	169,939	+62.6%	1.32%	+33.6%
ALXN	Sell	ALEXION PHARMACEUTICALS INC	$12,065,000	+7.8%	86,000	-6.5%	1.26%	-4.7%
CNC	Sell	CENTENE CORP DEL	$11,509,000	-15.2%	118,930	-30.0%	1.20%	-24.9%
LIVN	Buy	LIVANOVA PLC	$11,074,000	+76.0%	158,069	+53.8%	1.16%	+55.6%
ZBH	Buy	ZIMMER BIOMET HLDGS INC	$10,889,000	-3.6%	93,000	+5.7%	1.14%	-14.7%
BDX	Buy	BECTON DICKINSON & CO	$10,777,000	+6.2%	55,000	+5.8%	1.13%	-6.1%
TEVA	Buy	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$10,236,000	+8.0%	581,940	+104.0%	1.07%	-4.5%
THC	Buy	TENET HEALTHCARE CORP	$10,128,000	+59.4%	616,796	+87.8%	1.06%	+41.0%
ABBV	Sell	ABBVIE INC	$9,131,000	+9.9%	102,777	-10.3%	0.96%	-2.7%
VRTX	Sell	VERTEX PHARMACEUTICALS INC	$9,092,000	+3.1%	59,800	-12.6%	0.95%	-8.7%
AET	Buy	AETNA INC NEW	$9,016,000	+14.6%	56,700	+9.5%	0.94%	+1.4%
IART	Buy	INTEGRA LIFESCIENCES HLDGS C	$8,927,000	+2.1%	176,850	+10.3%	0.93%	-9.7%
CI	Sell	CIGNA CORPORATION	$8,908,000	-25.4%	47,650	-36.9%	0.93%	-34.0%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$8,878,000	-11.0%	75,593	-39.5%	0.93%	-21.2%
MNKKQ	Buy	MALLINCKRODT PUB LTD CO	$8,596,000	+3.7%	229,983	+24.4%	0.90%	-8.3%
LH	Buy	LABORATORY CORP AMER HLDGS	$8,255,000	+4.3%	54,680	+6.4%	0.86%	-7.8%
MGNX	Buy	MACROGENICS INC	$8,007,000	+44.5%	433,299	+36.9%	0.84%	+27.8%
HUM	Buy	HUMANA INC	$7,638,000	+19.8%	31,350	+18.3%	0.80%	+6.0%
BCR	Sell	BARD C R INC	$7,288,000	-38.2%	22,740	-39.0%	0.76%	-45.3%
Q	Buy	QUINTILES IMS HOLDING INC	$6,766,000	+13.6%	71,170	+7.0%	0.71%	+0.6%
LGND	Sell	LIGAND PHARAMCEUTICALS INC	$6,631,000	-13.8%	48,700	-23.2%	0.69%	-23.7%
SHPG	Sell	SHIRE PLCsponsored adr	$6,499,000	-27.0%	42,440	-21.2%	0.68%	-35.4%
HZNP	Buy	HORIZON PHARMA PLC	$6,173,000	+27.6%	486,463	+19.4%	0.65%	+12.9%
MYL	Sell	MYLAN N V	$5,684,000	-44.4%	181,200	-31.2%	0.59%	-50.8%
GNMK	Buy	GENMARK DIAGNOSTICS INC	$5,043,000	+5.2%	523,677	+29.2%	0.53%	-7.1%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$4,883,000	+91.7%	25,808	+76.8%	0.51%	+69.8%
EGRX	Sell	EAGLE PHARMACEUTICALS INC	$4,864,000	-53.3%	81,550	-38.2%	0.51%	-58.7%
BMRN	Sell	BIOMARIN PHARMACEUTICAL INC	$4,542,000	-23.1%	48,800	-24.9%	0.48%	-31.9%
ACAD	Sell	ACADIA PHARMACEUTICALS INC	$4,407,000	-24.7%	117,000	-37.1%	0.46%	-33.4%
AGN	Sell	ALLERGAN PLC	$4,201,000	-40.4%	20,500	-29.3%	0.44%	-47.4%
PRGO	Sell	PERRIGO CO PLC	$3,933,000	-46.0%	46,468	-51.8%	0.41%	-52.3%
RMD	Buy	RESMED INC	$3,617,000	+28.7%	47,000	+30.2%	0.38%	+13.9%
BLUE	Buy	BLUEBIRD BIO INC	$3,447,000	+48.4%	25,100	+13.6%	0.36%	+31.3%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$3,432,000	+58.7%	56,000	+19.1%	0.36%	+40.2%
XRAY	Buy	DENTSPLY SIRONA INC	$3,260,000	-0.4%	54,500	+7.9%	0.34%	-11.9%
HSIC	New	SCHEIN HENRY INC	$3,116,000	–	38,000	–	0.33%	–
IBB	Buy	ISHARES TRnasdq biotec etf	$3,002,000	+38.3%	9,000	+28.6%	0.31%	+22.2%
MOH	Buy	MOLINA HEALTHCARE INC	$2,991,000	+162.1%	43,500	+163.6%	0.31%	+131.9%
NKTR	Buy	NEKTAR THERAPEUTICS	$2,952,000	+251.0%	123,000	+186.0%	0.31%	+212.1%
ALKS	Sell	ALKERMES PLC	$2,852,000	-64.2%	56,100	-59.2%	0.30%	-68.4%
NUVA	Buy	NUVASIVE INC	$2,562,000	-5.7%	46,204	+30.9%	0.27%	-16.5%
UTHR	Buy	UNITED THERAPEUTICS CORP DEL	$2,531,000	+150.1%	21,600	+176.9%	0.26%	+120.8%
TFX	Buy	TELEFLEX INC	$2,468,000	+69.7%	10,200	+45.7%	0.26%	+50.0%
SGEN	Buy	SEATTLE GENETICS INC	$2,448,000	+21.3%	45,000	+15.4%	0.26%	+7.1%
PRTA	Sell	PROTHENA CORP PLC	$2,422,000	+9.1%	37,400	-8.8%	0.25%	-3.4%
DXCM	Buy	DEXCOM INC	$2,202,000	-19.7%	45,000	+20.0%	0.23%	-29.0%
HCSG	Buy	HEALTHCARE SVCS GRP INC	$2,051,000	+20.0%	38,000	+4.1%	0.22%	+6.4%
QGEN	Sell	QIAGEN NV	$1,941,000	-27.1%	61,611	-22.4%	0.20%	-35.6%
IPXL	Sell	IMPAX LABORATORIES INC	$1,766,000	-37.3%	87,000	-50.3%	0.18%	-44.4%
HCM	Buy	HUTCHISON CHINA MEDTECH LTDsponsored adr	$1,751,000	+156.7%	64,573	+120.8%	0.18%	+125.9%
IRTC	Buy	IRHYTHM TECHNOLOGIES INC	$1,733,000	+73.5%	33,400	+42.1%	0.18%	+53.4%
PTLA	Sell	PORTOLA PHARMACEUTICALS INC	$1,702,000	-15.8%	31,500	-12.5%	0.18%	-25.5%
GMED	Buy	GLOBUS MED INCcl a	$1,635,000	+23.3%	55,000	+37.5%	0.17%	+8.9%
TDOC	Buy	TELADOC INC	$1,558,000	+99.5%	47,000	+108.9%	0.16%	+77.2%
PEN	Buy	PENUMBRA INC	$1,517,000	+52.9%	16,800	+48.7%	0.16%	+35.9%
HALO	Sell	HALOZYME THERAPEUTICS INC	$1,522,000	-45.8%	87,600	-60.0%	0.16%	-52.1%
ACHC	New	ACADIA HEALTHCARE COMPANY IN	$1,481,000	–	31,000	–	0.16%	–
TRHC	Buy	TABULA RASA HEALTHCARE INC	$1,482,000	+167.0%	55,407	+50.1%	0.16%	+134.8%
TSRO	Sell	TESARO INC	$1,420,000	-46.6%	11,000	-42.1%	0.15%	-52.5%
XENT	Sell	INTERSECT ENT INC	$1,277,000	-54.3%	41,000	-59.0%	0.13%	-59.4%
DVAX	New	DYNAVAX TECHNOLOGIES CORP	$1,279,000	–	59,500	–	0.13%	–
HMSY	Buy	HMS HLDGS CORP	$1,063,000	+14.9%	53,500	+7.0%	0.11%	+1.8%
GKOS	Buy	GLAUKOS CORP	$990,000	+6.1%	30,000	+33.3%	0.10%	-5.5%
PODD	Buy	INSULET CORP	$991,000	+13.6%	18,000	+5.9%	0.10%	+1.0%
NVRO	Buy	NEVRO CORP	$972,000	+34.6%	10,700	+10.3%	0.10%	+20.0%
COTV	Buy	COTIVITI HLDGS INC	$781,000	+0.1%	21,708	+3.4%	0.08%	-10.9%
CVS	Sell	CVS HEALTH CORP	$716,000	-73.4%	8,800	-73.7%	0.08%	-76.4%
ADMS	New	ADAMAS PHARMACEUTICALS INC	$508,000	–	24,000	–	0.05%	–
OBLN	Buy	OBALON THERAPEUTICS INC	$457,000	+2.5%	48,000	+6.7%	0.05%	-9.4%
WBMD	Exit	WEBMD HEALTH CORP	$0	–	-7,400	–	-0.05%	–
DVA	Exit	DAVITA INC	$0	–	-10,000	–	-0.08%	–
BIB	Exit	PROSHARES TR	$0	–	-19,000	–	-0.12%	–
KITE	Exit	KITE PHARMA INC	$0	–	-17,000	–	-0.21%	–
CBPO	Exit	CHINA BIOLOGIC PRODS INC	$0	–	-36,250	–	-0.48%	–

Q2 2017

			Value		Shares		↓ Weighting
CELG	New	CELGENE CORP	$34,025,000	–	261,992	–	4.02%	–
AMGN	New	AMGEN INC	$28,199,000	–	163,728	–	3.33%	–
MDT	New	MEDTRONIC PLC	$27,113,000	–	305,500	–	3.21%	–
UNH	New	UNITEDHEALTH GROUP INC	$23,927,000	–	129,040	–	2.83%	–
ANTM	New	ANTHEM INC	$23,205,000	–	123,347	–	2.74%	–
EW	New	EDWARDS LIFESCIENCES CORP	$22,454,000	–	189,900	–	2.66%	–
ISRG	New	INTUITIVE SURGICAL INC	$22,174,000	–	23,706	–	2.62%	–
GILD	New	GILEAD SCIENCES INC	$22,069,000	–	311,803	–	2.61%	–
ABT	New	ABBOTT LABS	$21,534,000	–	443,000	–	2.55%	–
ALGN	New	ALIGN TECHNOLOGY INC	$20,446,000	–	136,200	–	2.42%	–
ILMN	New	ILLUMINA INC	$18,821,000	–	108,465	–	2.22%	–
BSX	New	BOSTON SCIENTIFIC CORP	$17,408,000	–	628,000	–	2.06%	–
BIIB	New	BIOGEN INC	$16,689,000	–	61,500	–	1.97%	–
JAZZ	New	JAZZ PHARMACEUTICALS PLC	$15,582,000	–	100,203	–	1.84%	–
INCY	New	INCYTE CORP	$15,539,000	–	123,412	–	1.84%	–
LLY	New	LILLY ELI & CO	$14,902,000	–	181,073	–	1.76%	–
WBA	New	WALGREENS BOOTS ALLIANCE INC	$14,556,000	–	185,872	–	1.72%	–
REGN	New	REGENERON PHARMACEUTICALS	$13,801,000	–	28,100	–	1.63%	–
CNC	New	CENTENE CORP DEL	$13,564,000	–	169,810	–	1.60%	–
BAX	New	BAXTER INTL INC	$12,471,000	–	206,000	–	1.48%	–
HOLX	New	HOLOGIC INC	$12,408,000	–	273,423	–	1.47%	–
DHR	New	DANAHER CORP DEL	$12,068,000	–	143,000	–	1.43%	–
ABMD	New	ABIOMED INC	$12,033,000	–	83,970	–	1.42%	–
CI	New	CIGNA CORPORATION	$11,948,000	–	75,500	–	1.41%	–
BCR	New	BARD C R INC	$11,788,000	–	37,290	–	1.39%	–
SYK	New	STRYKER CORP	$11,699,000	–	84,300	–	1.38%	–
IONS	New	IONIS PHARMACEUTICALS INC	$11,423,000	–	224,562	–	1.35%	–
ZBH	New	ZIMMER BIOMET HLDGS INC	$11,299,000	–	88,000	–	1.34%	–
ALXN	New	ALEXION PHARMACEUTICALS INC	$11,194,000	–	92,000	–	1.32%	–
ABC	New	AMERISOURCEBERGEN CORP	$10,687,000	–	113,058	–	1.26%	–
EGRX	New	EAGLE PHARMACEUTICALS INC	$10,413,000	–	131,990	–	1.23%	–
MYL	New	MYLAN N V	$10,217,000	–	263,200	–	1.21%	–
BDX	New	BECTON DICKINSON & CO	$10,146,000	–	52,000	–	1.20%	–
ALNY	New	ALNYLAM PHARMACEUTICALS INC	$9,972,000	–	125,029	–	1.18%	–
TEVA	New	TEVA PHARMACEUTICAL INDS LTDsponsored adr	$9,479,000	–	285,329	–	1.12%	–
WMGI	New	WRIGHT MED GROUP NV	$9,238,000	–	336,055	–	1.09%	–
SHPG	New	SHIRE PLCsponsored adr	$8,906,000	–	53,885	–	1.05%	–
VRTX	New	VERTEX PHARMACEUTICALS INC	$8,815,000	–	68,400	–	1.04%	–
IART	New	INTEGRA LIFESCIENCES HLDGS C	$8,741,000	–	160,350	–	1.03%	–
HRC	New	HILL ROM HLDGS INC	$8,319,000	–	104,503	–	0.98%	–
ABBV	New	ABBVIE INC	$8,308,000	–	114,574	–	0.98%	–
MNKKQ	New	MALLINCKRODT PUB LTD CO	$8,287,000	–	184,945	–	0.98%	–
ALKS	New	ALKERMES PLC	$7,977,000	–	137,600	–	0.94%	–
LH	New	LABORATORY CORP AMER HLDGS	$7,918,000	–	51,370	–	0.94%	–
AET	New	AETNA INC NEW	$7,865,000	–	51,800	–	0.93%	–
LGND	New	LIGAND PHARAMCEUTICALS INC	$7,697,000	–	63,400	–	0.91%	–
PRGO	New	PERRIGO CO PLC	$7,285,000	–	96,468	–	0.86%	–
AGN	New	ALLERGAN PLC	$7,050,000	–	29,000	–	0.83%	–
HUM	New	HUMANA INC	$6,376,000	–	26,500	–	0.75%	–
THC	New	TENET HEALTHCARE CORP	$6,353,000	–	328,506	–	0.75%	–
LIVN	New	LIVANOVA PLC	$6,293,000	–	102,808	–	0.74%	–
Q	New	QUINTILES IMS HOLDING INC	$5,954,000	–	66,520	–	0.70%	–
BMRN	New	BIOMARIN PHARMACEUTICAL INC	$5,903,000	–	65,000	–	0.70%	–
ACAD	New	ACADIA PHARMACEUTICALS INC	$5,854,000	–	186,000	–	0.69%	–
COO	New	COOPER COS INC	$5,746,000	–	24,000	–	0.68%	–
MGNX	New	MACROGENICS INC	$5,540,000	–	316,418	–	0.66%	–
CERN	New	CERNER CORP	$4,952,000	–	74,500	–	0.59%	–
HZNP	New	HORIZON PHARMA PLC	$4,836,000	–	407,398	–	0.57%	–
GNMK	New	GENMARK DIAGNOSTICS INC	$4,793,000	–	405,178	–	0.57%	–
JNJ	New	JOHNSON & JOHNSON	$4,167,000	–	31,500	–	0.49%	–
CBPO	New	CHINA BIOLOGIC PRODS INC	$4,100,000	–	36,250	–	0.48%	–
XRAY	New	DENTSPLY SIRONA INC	$3,274,000	–	50,500	–	0.39%	–
ESRX	New	EXPRESS SCRIPTS HLDG CO	$3,160,000	–	49,500	–	0.37%	–
MCK	New	MCKESSON CORP	$2,962,000	–	18,000	–	0.35%	–
IPXL	New	IMPAX LABORATORIES INC	$2,818,000	–	175,000	–	0.33%	–
HALO	New	HALOZYME THERAPEUTICS INC	$2,808,000	–	219,000	–	0.33%	–
RMD	New	RESMED INC	$2,811,000	–	36,100	–	0.33%	–
XENT	New	INTERSECT ENT INC	$2,795,000	–	100,000	–	0.33%	–
DXCM	New	DEXCOM INC	$2,743,000	–	37,500	–	0.32%	–
NUVA	New	NUVASIVE INC	$2,716,000	–	35,304	–	0.32%	–
CVS	New	CVS HEALTH CORP	$2,687,000	–	33,400	–	0.32%	–
QGEN	New	QIAGEN NV	$2,664,000	–	79,444	–	0.32%	–
TSRO	New	TESARO INC	$2,657,000	–	19,000	–	0.31%	–
TMO	New	THERMO FISHER SCIENTIFIC INC	$2,547,000	–	14,600	–	0.30%	–
BLUE	New	BLUEBIRD BIO INC	$2,322,000	–	22,100	–	0.28%	–
AGIO	New	AGIOS PHARMACEUTICALS INC	$2,315,000	–	45,000	–	0.27%	–
PRTA	New	PROTHENA CORP PLC	$2,219,000	–	41,000	–	0.26%	–
IBB	New	ISHARES TRnasdq biotec etf	$2,171,000	–	7,000	–	0.26%	–
NBIX	New	NEUROCRINE BIOSCIENCES INC	$2,162,000	–	47,000	–	0.26%	–
PTLA	New	PORTOLA PHARMACEUTICALS INC	$2,022,000	–	36,000	–	0.24%	–
SGEN	New	SEATTLE GENETICS INC	$2,018,000	–	39,000	–	0.24%	–
HCA	New	HCA HEALTHCARE INC	$1,857,000	–	21,300	–	0.22%	–
KITE	New	KITE PHARMA INC	$1,762,000	–	17,000	–	0.21%	–
MRK	New	MERCK & CO INC	$1,762,000	–	27,500	–	0.21%	–
CLVS	New	CLOVIS ONCOLOGY INC	$1,732,000	–	18,500	–	0.20%	–
HCSG	New	HEALTHCARE SVCS GRP INC	$1,709,000	–	36,500	–	0.20%	–
RDUS	New	RADIUS HEALTH INC	$1,651,000	–	36,500	–	0.20%	–
ANGO	New	ANGIODYNAMICS INC	$1,649,000	–	101,700	–	0.20%	–
RARE	New	ULTRAGENYX PHARMACEUTICAL INC	$1,615,000	–	42,000	–	0.19%	–
CAH	New	CARDINAL HEALTH INC	$1,558,000	–	20,000	–	0.18%	–
EARS	New	AURIS MED HLDG AG	$1,551,000	–	2,169,625	–	0.18%	–
MASI	New	MASIMO CORP	$1,550,000	–	17,000	–	0.18%	–
TFX	New	TELEFLEX INC	$1,454,000	–	7,000	–	0.17%	–
BIVV	New	BIOVERATIV INC	$1,369,000	–	22,750	–	0.16%	–
GMED	New	GLOBUS MED INCcl a	$1,326,000	–	40,000	–	0.16%	–
JUNO	New	JUNO THERAPEUTICS INC	$1,285,000	–	43,000	–	0.15%	–
ENDP	New	ENDO INTL PLC	$1,285,000	–	115,000	–	0.15%	–
EXEL	New	EXELIXIS INC	$1,281,000	–	52,000	–	0.15%	–
MOH	New	MOLINA HEALTHCARE INC	$1,141,000	–	16,500	–	0.14%	–
INO	New	INOVIO PHARMACEUTICALS INC	$1,129,000	–	144,000	–	0.13%	–
ICPT	New	INTERCEPT PHARMACEUTICALS IN	$1,029,000	–	8,500	–	0.12%	–
BIB	New	PROSHARES TR	$1,015,000	–	19,000	–	0.12%	–
UTHR	New	UNITED THERAPEUTICS CORP DEL	$1,012,000	–	7,800	–	0.12%	–
IRTC	New	IRHYTHM TECHNOLOGIES INC	$999,000	–	23,500	–	0.12%	–
PEN	New	PENUMBRA INC	$992,000	–	11,300	–	0.12%	–
PFE	New	PFIZER INC	$981,000	–	29,200	–	0.12%	–
GKOS	New	GLAUKOS CORP	$933,000	–	22,500	–	0.11%	–
HMSY	New	HMS HLDGS CORP	$925,000	–	50,000	–	0.11%	–
PODD	New	INSULET CORP	$872,000	–	17,000	–	0.10%	–
NKTR	New	NEKTAR THERAPEUTICS	$841,000	–	43,000	–	0.10%	–
EVHC	New	ENVISION HEALTHCARE CORP	$816,000	–	13,026	–	0.10%	–
QTNT	New	QUOTIENT LTD	$810,000	–	110,000	–	0.10%	–
COTV	New	COTIVITI HLDGS INC	$780,000	–	21,000	–	0.09%	–
TDOC	New	TELADOC INC	$781,000	–	22,500	–	0.09%	–
CEMP	New	CEMPRA INC	$759,000	–	165,000	–	0.09%	–
MDCO	New	MEDICINES CO	$741,000	–	19,500	–	0.09%	–
NVRO	New	NEVRO CORP	$722,000	–	9,700	–	0.08%	–
VAR	New	VARIAN MED SYS INC	$722,000	–	7,000	–	0.08%	–
SGRY	New	SURGERY PARTNERS INC	$705,000	–	31,000	–	0.08%	–
HCM	New	HUTCHISON CHINA MEDTECH LTDsponsored adr	$682,000	–	29,242	–	0.08%	–
DVA	New	DAVITA INC	$648,000	–	10,000	–	0.08%	–
GWPH	New	GW PHARMACEUTICALS PLCads	$602,000	–	6,000	–	0.07%	–
TBPH	New	THERAVANCE BIOPHARMA INC	$575,000	–	14,428	–	0.07%	–
TRHC	New	TABULA RASA HEALTHCARE INC	$555,000	–	36,907	–	0.07%	–
ITCI	New	INTRA CELLULAR THERAPIES INC	$497,000	–	40,000	–	0.06%	–
OBLN	New	OBALON THERAPEUTICS INC	$446,000	–	45,000	–	0.05%	–
WBMD	New	WEBMD HEALTH CORP	$434,000	–	7,400	–	0.05%	–
CLDX	New	CELLDEX THERAPEUTICS INC NEW	$395,000	–	160,000	–	0.05%	–
ALDR	New	ALDER BIOPHARMACEUTICALS INC	$378,000	–	33,000	–	0.04%	–
ESPR	New	ESPERION THERAPEUTICS INC NEW	$370,000	–	8,000	–	0.04%	–
MYGN	New	MYRIAD GENETICS INC	$336,000	–	13,000	–	0.04%	–
AACH	New	AAC HLDGS INC	$312,000	–	45,000	–	0.04%	–

Q4 2016

			Value		Shares		↓ Weighting
EIGR	Exit	Eiger BioPharmaceuticals, Inc.	$0	–	-3,333	–	-0.01%	–
QHCCQ	Exit	Quorum Health Corp	$0	–	-12,500	–	-0.01%	–
MYGN	Exit	Myriad Genetics, Inc.	$0	–	-14,000	–	-0.05%	–
SGRY	Exit	Surgery Partners, Inc.	$0	–	-15,000	–	-0.06%	–
WBMD	Exit	Webmd Health Corp	$0	–	-7,400	–	-0.07%	–
PEN	Exit	Penumbra, Inc.	$0	–	-5,000	–	-0.07%	–
RMD	Exit	ResMed Inc.	$0	–	-8,000	–	-0.09%	–
ESPR	Exit	Esperion Therapeutics Inc.	$0	–	-40,000	–	-0.10%	–
PODD	Exit	Insulet Corporation	$0	–	-15,000	–	-0.11%	–
CLDX	Exit	Celldex Therapeutics, Inc.	$0	–	-160,000	–	-0.12%	–
DVA	Exit	Davita Healthcare Partners, Inc.	$0	–	-10,000	–	-0.12%	–
TBPH	Exit	Theravance Biopharma, Inc.	$0	–	-18,428	–	-0.12%	–
NVAX	Exit	Novavax, Inc.	$0	–	-325,000	–	-0.12%	–
VAR	Exit	Varian Medical Systems, Inc.	$0	–	-7,000	–	-0.13%	–
UTHR	Exit	United Therapeutics Corporation	$0	–	-6,300	–	-0.13%	–
EXEL	Exit	Exelixis, Inc.	$0	–	-60,000	–	-0.14%	–
AACH	Exit	AAC Hldgs Inc	$0	–	-45,000	–	-0.14%	–
NVRO	Exit	Nevro Corp.	$0	–	-7,500	–	-0.14%	–
KITE	Exit	Kite Pharma, Inc.	$0	–	-14,000	–	-0.14%	–
GWPH	Exit	GW Pharmaceuticals PLCads	$0	–	-6,000	–	-0.14%	–
TMH	Exit	Team Health Holdings Inc.	$0	–	-25,000	–	-0.15%	–
PTLA	Exit	Portola Pharmaceuticals Inc.	$0	–	-36,000	–	-0.15%	–
QTNT	Exit	Quotient Limited	$0	–	-110,000	–	-0.16%	–
CVS	Exit	CVS Health Corporation	$0	–	-9,700	–	-0.16%	–
EVHC	Exit	Envision Healthcare Hldgs Inc.	$0	–	-39,000	–	-0.16%	–
ABBV	Exit	Abbvie Inc.	$0	–	-15,000	–	-0.17%	–
MOH	Exit	Molina Healthcare Inc.	$0	–	-16,500	–	-0.17%	–
ALDR	Exit	Alder Biopharmaceuticals Inc.	$0	–	-33,000	–	-0.20%	–
TFX	Exit	Teleflex Incorporated	$0	–	-6,500	–	-0.20%	–
LH	Exit	Laboratory Corporation of America Holdings	$0	–	-8,000	–	-0.20%	–
JUNO	Exit	Juno Therapeutics, Inc.	$0	–	-37,000	–	-0.20%	–
LABU	Exit	Direxion SHS ETF TRsp biotech bl new	$0	–	-25,175	–	-0.22%	–
BMY	Exit	Bristol-Myers Squibb Company	$0	–	-23,000	–	-0.22%	–
ALR	Exit	Alere Inc	$0	–	-30,000	–	-0.23%	–
INSYQ	Exit	Insys Therapeutics Inc.	$0	–	-115,000	–	-0.24%	–
ACAD	Exit	Acadia Pharmaceuticals, Inc.	$0	–	-45,000	–	-0.26%	–
INO	Exit	Inovio Pharmaceuticals, Inc.	$0	–	-155,000	–	-0.26%	–
HCSG	Exit	Healthcare Services Group Inc.	$0	–	-38,100	–	-0.27%	–
CLVS	Exit	Clovis Oncology Inc.	$0	–	-43,000	–	-0.28%	–
ALNY	Exit	Alnylam Pharmaceuticals Inc.	$0	–	-24,000	–	-0.29%	–
PFE	Exit	Pfizer Inc.	$0	–	-50,000	–	-0.31%	–
WMGI	Exit	Wright Med Group N V	$0	–	-70,309	–	-0.31%	–
AET	Exit	Aetna Inc.	$0	–	-16,400	–	-0.34%	–
HUM	Exit	Humana, Inc.	$0	–	-10,800	–	-0.34%	–
ACHN	Exit	Achillion Pharmaceuticals, Inc.	$0	–	-240,000	–	-0.35%	–
BLUE	Exit	Bluebird Bio, Inc.	$0	–	-29,000	–	-0.36%	–
GMED	Exit	Globus Medical, Inc.cl a	$0	–	-87,700	–	-0.36%	–
EGRX	Exit	Eagle Pharmaceuticals Inc.	$0	–	-29,000	–	-0.37%	–
HZNP	Exit	Horizon Pharma plc	$0	–	-117,000	–	-0.38%	–
BIB	Exit	ProShares Trust	$0	–	-45,500	–	-0.40%	–
ICPT	Exit	Intercept Pharmaceuticals, Inc.	$0	–	-13,500	–	-0.40%	–
IPXL	Exit	Impax Laboratories, Inc.	$0	–	-95,000	–	-0.41%	–
ANGO	Exit	AngioDynamics, Inc.	$0	–	-130,000	–	-0.41%	–
SGEN	Exit	Seattle Genetics, Inc.	$0	–	-43,000	–	-0.42%	–
ZLTQ	Exit	Zeltiq Aesthetics Inc.	$0	–	-60,000	–	-0.42%	–
HCA	Exit	HCA Holdings, Inc.	$0	–	-31,200	–	-0.43%	–
AGIO	Exit	Agios Pharmaceuticals, Inc.	$0	–	-45,000	–	-0.43%	–
ALKS	Exit	Alkermes Public Limited Company	$0	–	-51,500	–	-0.44%	–
PRTA	Exit	Prothena Corporation plc	$0	–	-41,000	–	-0.44%	–
MGNX	Exit	Macrogenics, Inc.	$0	–	-83,000	–	-0.45%	–
QGEN	Exit	Qiagen NV	$0	–	-91,500	–	-0.45%	–
TMO	Exit	Thermo Fisher Scientific Inc.	$0	–	-16,000	–	-0.46%	–
ANTM	Exit	Anthem, Inc.	$0	–	-20,600	–	-0.47%	–
NVDQ	Exit	Novadaq Technologies Inc.	$0	–	-230,000	–	-0.48%	–
LLY	Exit	Lilly Eli & Co.	$0	–	-35,000	–	-0.51%	–
MRK	Exit	Merck & Co., Inc.	$0	–	-47,000	–	-0.53%	–
NBIX	Exit	Neurocrine Biosciences, Inc.	$0	–	-58,000	–	-0.53%	–
RARE	Exit	Ultragenyx Pharmaceuticals Inc.	$0	–	-43,000	–	-0.55%	–
NKTR	Exit	Nektar Therapeutics	$0	–	-186,000	–	-0.58%	–
XENT	Exit	Intersect Ent, Inc.	$0	–	-205,325	–	-0.59%	–
RDUS	Exit	Radius Health Inc.	$0	–	-61,000	–	-0.60%	–
ESRX	Exit	Express Scripts Holding Company	$0	–	-49,500	–	-0.63%	–
EARS	Exit	Auris Medical Holding AG	$0	–	-2,169,625	–	-0.68%	–
ENDP	Exit	Endo International PLC	$0	–	-190,000	–	-0.69%	–
HALO	Exit	Halozyme Therapeutics, Inc.	$0	–	-318,000	–	-0.69%	–
IBB	Exit	iSHARES Trustnasdq biotec etf	$0	–	-13,500	–	-0.71%	–
PRGO	Exit	Perrigo Company plc	$0	–	-42,700	–	-0.71%	–
IONS	Exit	Ionis Pharmaceuticals Inc.	$0	–	-108,000	–	-0.72%	–
NUVA	Exit	Nuvasive, Inc.	$0	–	-60,000	–	-0.72%	–
MCK	Exit	McKesson Corporation	$0	–	-24,000	–	-0.72%	–
MASI	Exit	Masimo Corporation	$0	–	-70,000	–	-0.75%	–
COO	Exit	Cooper Companies Inc.	$0	–	-23,500	–	-0.76%	–
AMSG	Exit	Amsurg Corp	$0	–	-71,400	–	-0.86%	–
CHRS	Exit	Coherus BioSciences, Inc	$0	–	-202,000	–	-0.98%	–
BCR	Exit	C.R. Bard, Inc.	$0	–	-25,000	–	-1.01%	–
MNKKQ	Exit	Mallinckrodt Pub Ltd Co.	$0	–	-80,800	–	-1.02%	–
JNJ	Exit	Johnson & Johnson	$0	–	-50,000	–	-1.07%	–
BMRN	Exit	BioMarin Pharmaceutical Inc.	$0	–	-65,000	–	-1.09%	–
ALXN	Exit	Alexion Pharmaceuticals, Inc.	$0	–	-49,400	–	-1.09%	–
CERN	Exit	Cerner Corporation	$0	–	-98,500	–	-1.10%	–
AGN	Exit	Allergan PLC	$0	–	-29,400	–	-1.22%	–
ARIA	Exit	ARIAD Pharmaceuticals, Inc.	$0	–	-495,000	–	-1.22%	–
AKRXQ	Exit	Akorn Inc	$0	–	-252,000	–	-1.24%	–
ABMD	Exit	Abiomed Inc	$0	–	-55,450	–	-1.29%	–
SHPG	Exit	Shire PLCsponsored adr	$0	–	-38,090	–	-1.33%	–
VRTX	Exit	Vertex Pharmaceuticals Incorporated	$0	–	-85,000	–	-1.34%	–
CI	Exit	Cigna Corporation	$0	–	-59,722	–	-1.41%	–
INCY	Exit	Incyte Corporation	$0	–	-91,000	–	-1.55%	–
TEVA	Exit	Teva Pharmaceuticals Industries Ltdadr	$0	–	-187,190	–	-1.56%	–
ISRG	Exit	Intuitive Surgical, Inc.	$0	–	-12,000	–	-1.57%	–
CAH	Exit	Cardinal Health, Inc.	$0	–	-114,280	–	-1.60%	–
MYL	Exit	Mylan N V	$0	–	-235,700	–	-1.62%	–
BAX	Exit	Baxter International Inc.	$0	–	-190,000	–	-1.63%	–
HOLX	Exit	Hologic, Inc.	$0	–	-242,100	–	-1.70%	–
CNC	Exit	Centene Corporation	$0	–	-141,430	–	-1.71%	–
BDX	Exit	Becton, Dickinson and Company	$0	–	-55,000	–	-1.79%	–
JAZZ	Exit	Jazz Pharmaceuticals Public Limited Company	$0	–	-83,800	–	-1.84%	–
EW	Exit	Edwards Lifesciences Corporation	$0	–	-85,000	–	-1.85%	–
ZBH	Exit	Zimmer Biomet Holdings, Inc.	$0	–	-80,000	–	-1.88%	–
LGND	Exit	Ligand Pharmaceuticals Incorporated	$0	–	-106,880	–	-1.97%	–
GILD	Exit	Gilead Sciences, Inc.	$0	–	-156,500	–	-2.24%	–
BSX	Exit	Boston Scientific Corporation	$0	–	-575,000	–	-2.47%	–
UNH	Exit	UnitedHealth Group Incorporated	$0	–	-99,200	–	-2.51%	–
AMGN	Exit	Amgen Inc.	$0	–	-83,500	–	-2.52%	–
REGN	Exit	Regeneron Pharmaceuticals, Inc.	$0	–	-38,000	–	-2.76%	–
ABT	Exit	Abbott Laboratories	$0	–	-384,000	–	-2.93%	–
BIIB	Exit	Biogen Inc.	$0	–	-54,500	–	-3.08%	–
ILMN	Exit	Illumina, Inc.	$0	–	-94,475	–	-3.10%	–
CELG	Exit	Celgene Corporation	$0	–	-194,250	–	-3.67%	–
SYK	Exit	Stryker Corporation	$0	–	-180,800	–	-3.80%	–
MDT	Exit	Medtronic PLC	$0	–	-247,500	–	-3.86%	–

Q3 2016

			Value		Shares		↓ Weighting
MDT	Sell	Medtronic PLC	$21,384,000	-12.8%	247,500	-12.4%	3.86%	-16.2%
SYK	Buy	Stryker Corporation	$21,047,000	-0.8%	180,800	+2.1%	3.80%	-4.7%
CELG	Sell	Celgene Corporation	$20,305,000	+5.0%	194,250	-0.9%	3.67%	+0.8%
ILMN	Buy	Illumina, Inc.	$17,162,000	+33.5%	94,475	+3.2%	3.10%	+28.2%
ABT	Buy	Abbott Laboratories	$16,239,000	+8.3%	384,000	+0.7%	2.93%	+4.0%
REGN	Buy	Regeneron Pharmaceuticals, Inc.	$15,277,000	+45.8%	38,000	+26.7%	2.76%	+40.0%
BSX	Buy	Boston Scientific Corporation	$13,685,000	+17.1%	575,000	+15.0%	2.47%	+12.4%
LGND	Buy	Ligand Pharmaceuticals Incorporated	$10,908,000	+28.8%	106,880	+50.5%	1.97%	+23.7%
ZBH	Sell	Zimmer Biomet Holdings, Inc.	$10,402,000	+0.2%	80,000	-7.2%	1.88%	-3.8%
EW	Buy	Edwards Lifesciences Corporation	$10,248,000	+51.1%	85,000	+25.0%	1.85%	+45.1%
JAZZ	Buy	Jazz Pharmaceuticals Public Limited Company	$10,180,000	-4.3%	83,800	+11.3%	1.84%	-8.1%
BDX	Sell	Becton, Dickinson and Company	$9,885,000	-1.2%	55,000	-6.8%	1.79%	-5.2%
CNC	Buy	Centene Corporation	$9,470,000	+13.0%	141,430	+20.5%	1.71%	+8.6%
HOLX	Buy	Hologic, Inc.	$9,401,000	+14.0%	242,100	+1.6%	1.70%	+9.5%
BAX	Buy	Baxter International Inc.	$9,044,000	+20.5%	190,000	+14.5%	1.63%	+15.6%
MYL	Buy	Mylan N V	$8,985,000	+73.6%	235,700	+96.9%	1.62%	+66.6%
CAH	Sell	Cardinal Health, Inc.	$8,880,000	-39.7%	114,280	-39.5%	1.60%	-42.1%
TEVA	Sell	Teva Pharmaceuticals Industries Ltdadr	$8,613,000	-25.2%	187,190	-18.3%	1.56%	-28.2%
CI	Buy	Cigna Corporation	$7,783,000	+26.7%	59,722	+24.4%	1.41%	+21.6%
VRTX	Buy	Vertex Pharmaceuticals Incorporated	$7,413,000	+30.6%	85,000	+28.8%	1.34%	+25.4%
SHPG	Sell	Shire PLCsponsored adr	$7,384,000	+3.2%	38,090	-2.0%	1.33%	-0.9%
ABMD	Sell	Abiomed Inc	$7,130,000	+14.1%	55,450	-3.1%	1.29%	+9.5%
AKRXQ	Buy	Akorn Inc	$6,870,000	+89.9%	252,000	+98.4%	1.24%	+82.2%
AGN	Sell	Allergan PLC	$6,771,000	-16.5%	29,400	-16.2%	1.22%	-19.9%
CERN	Buy	Cerner Corporation	$6,082,000	+73.0%	98,500	+64.2%	1.10%	+66.0%
MNKKQ	Buy	Mallinckrodt Pub Ltd Co.	$5,638,000	+97.3%	80,800	+71.9%	1.02%	+89.4%
CHRS	Sell	Coherus BioSciences, Inc	$5,410,000	+5.4%	202,000	-33.6%	0.98%	+1.1%
AMSG	Sell	Amsurg Corp	$4,787,000	-16.6%	71,400	-3.5%	0.86%	-19.9%
MASI	Sell	Masimo Corporation	$4,164,000	+5.7%	70,000	-6.7%	0.75%	+1.5%
MCK	Sell	McKesson Corporation	$4,002,000	-17.5%	24,000	-7.7%	0.72%	-20.8%
PRGO	Sell	Perrigo Company plc	$3,942,000	-1.2%	42,700	-3.0%	0.71%	-5.2%
IBB	Buy	iSHARES Trustnasdq biotec etf	$3,908,000	+78.7%	13,500	+58.8%	0.71%	+71.4%
ENDP	Buy	Endo International PLC	$3,829,000	+372.1%	190,000	+265.4%	0.69%	+352.3%
ESRX	Sell	Express Scripts Holding Company	$3,491,000	-29.1%	49,500	-23.8%	0.63%	-31.9%
RDUS	Buy	Radius Health Inc.	$3,299,000	+124.4%	61,000	+52.5%	0.60%	+115.2%
RARE	Buy	Ultragenyx Pharmaceuticals Inc.	$3,050,000	+122.8%	43,000	+53.6%	0.55%	+113.6%
NVDQ	Sell	Novadaq Technologies Inc.	$2,661,000	+0.2%	230,000	-14.8%	0.48%	-3.8%
ANTM	Buy	Anthem, Inc.	$2,581,000	+40.3%	20,600	+47.1%	0.47%	+34.7%
TMO	Sell	Thermo Fisher Scientific Inc.	$2,545,000	-13.9%	16,000	-20.0%	0.46%	-17.3%
PRTA	Buy	Prothena Corporation plc	$2,459,000	+126.8%	41,000	+32.3%	0.44%	+117.6%
ALKS	Sell	Alkermes Public Limited Company	$2,422,000	-14.4%	51,500	-21.4%	0.44%	-17.8%
AGIO	Buy	Agios Pharmaceuticals, Inc.	$2,377,000	+57.6%	45,000	+25.0%	0.43%	+51.1%
HCA	Sell	HCA Holdings, Inc.	$2,360,000	-29.9%	31,200	-28.6%	0.43%	-32.7%
SGEN	Sell	Seattle Genetics, Inc.	$2,322,000	-15.5%	43,000	-36.8%	0.42%	-18.8%
ANGO	Sell	AngioDynamics, Inc.	$2,280,000	+4.8%	130,000	-14.1%	0.41%	+0.7%
BIB	Buy	ProShares Trust	$2,205,000	+177.0%	45,500	+122.0%	0.40%	+165.3%
EGRX	New	Eagle Pharmaceuticals Inc.	$2,030,000	–	29,000	–	0.37%	–
ACHN	Sell	Achillion Pharmaceuticals, Inc.	$1,944,000	-40.7%	240,000	-42.9%	0.35%	-43.0%
HUM	Sell	Humana, Inc.	$1,910,000	-64.6%	10,800	-64.0%	0.34%	-66.0%
AET	Sell	Aetna Inc.	$1,893,000	-40.2%	16,400	-36.7%	0.34%	-42.5%
CLVS	New	Clovis Oncology Inc.	$1,550,000	–	43,000	–	0.28%	–
INSYQ	New	Insys Therapeutics Inc.	$1,356,000	–	115,000	–	0.24%	–
LABU	Sell	Direxion SHS ETF TRsp biotech bl new	$1,228,000	-21.1%	25,175	-54.4%	0.22%	-24.2%
TFX	Sell	Teleflex Incorporated	$1,092,000	-38.5%	6,500	-35.1%	0.20%	-41.0%
MOH	New	Molina Healthcare Inc.	$962,000	–	16,500	–	0.17%	–
CVS	Sell	CVS Health Corporation	$863,000	-88.7%	9,700	-87.8%	0.16%	-89.2%
QTNT	Buy	Quotient Limited	$860,000	+11.0%	110,000	+10.0%	0.16%	+6.2%
PTLA	New	Portola Pharmaceuticals Inc.	$818,000	–	36,000	–	0.15%	–
TMH	Buy	Team Health Holdings Inc.	$814,000	+33.4%	25,000	+66.7%	0.15%	+27.8%
GWPH	New	GW Pharmaceuticals PLCads	$796,000	–	6,000	–	0.14%	–
EXEL	Sell	Exelixis, Inc.	$767,000	-42.2%	60,000	-64.7%	0.14%	-44.4%
VAR	Sell	Varian Medical Systems, Inc.	$697,000	-57.6%	7,000	-65.0%	0.13%	-59.4%
TBPH	Buy	Theravance Biopharma, Inc.	$668,000	+157.9%	18,428	+61.3%	0.12%	+146.9%
DVA	Sell	Davita Healthcare Partners, Inc.	$661,000	-34.2%	10,000	-23.1%	0.12%	-37.0%
WBMD	New	Webmd Health Corp	$368,000	–	7,400	–	0.07%	–
TTPH	Exit	Tetraphase Pharmaceuticals, Inc.	$0	–	-22,000	–	-0.02%	–
ZFGN	Exit	Zafgen, Inc.	$0	–	-20,000	–	-0.02%	–
INFI	Exit	Infinity Pharmaceuticals, Inc.	$0	–	-160,000	–	-0.04%	–
HTWR	Exit	Heartware International, Inc.	$0	–	-3,813	–	-0.04%	–
THC	Exit	Tenet Healthcare Corporation	$0	–	-10,000	–	-0.05%	–
CYH	Exit	Community Health Systems, Inc.	$0	–	-50,000	–	-0.11%	–
CPHD	Exit	Cepheid Inc.	$0	–	-30,000	–	-0.17%	–
SUPN	Exit	Supernus Pharmaceuticals, Inc.	$0	–	-164,000	–	-0.63%	–
STJ	Exit	St. Jude Medical, Inc.	$0	–	-60,000	–	-0.88%	–
MDVN	Exit	Medivation, Inc.	$0	–	-78,000	–	-0.88%	–

Q2 2016

			Value		Shares		↓ Weighting
MDT	New	Medtronic, Inc.	$24,513,000	–	282,500	–	4.61%	–
SYK	New	Stryker Corporation	$21,210,000	–	177,000	–	3.99%	–
CELG	New	Celgene Corporation	$19,336,000	–	196,050	–	3.64%	–
ABT	New	Abbott Laboratories	$14,997,000	–	381,500	–	2.82%	–
CAH	New	Cardinal Health, Inc.	$14,727,000	–	188,780	–	2.77%	–
UNH	New	UnitedHealth Group Incorporated	$14,007,000	–	99,200	–	2.64%	–
BIIB	New	Biogen Inc.	$13,179,000	–	54,500	–	2.48%	–
GILD	New	Gilead Sciences, Inc.	$13,055,000	–	156,500	–	2.46%	–
ILMN	New	Illumina, Inc.	$12,855,000	–	91,575	–	2.42%	–
AMGN	New	Amgen Inc.	$12,705,000	–	83,500	–	2.39%	–
BSX	New	Boston Scientific Corporation	$11,685,000	–	500,000	–	2.20%	–
TEVA	New	Teva Pharmaceuticals Industries Ltdadr	$11,512,000	–	229,190	–	2.17%	–
JAZZ	New	Jazz Pharmaceuticals Public Limited Company	$10,641,000	–	75,300	–	2.00%	–
REGN	New	Regeneron Pharmaceuticals, Inc.	$10,477,000	–	30,000	–	1.97%	–
ZBH	New	Zimmer Biomet Holdings, Inc.	$10,377,000	–	86,200	–	1.95%	–
BDX	New	Becton, Dickinson and Company	$10,006,000	–	59,000	–	1.88%	–
EARS	New	Auris Medical Holding AG	$9,091,000	–	2,169,625	–	1.71%	–
LGND	New	Ligand Pharmaceuticals Incorporated	$8,472,000	–	71,030	–	1.59%	–
CNC	New	Centene Corporation	$8,377,000	–	117,380	–	1.58%	–
HOLX	New	Hologic, Inc.	$8,245,000	–	238,300	–	1.55%	–
AGN	New	Allergan PLC	$8,111,000	–	35,100	–	1.53%	–
ISRG	New	Intuitive Surgical, Inc.	$7,937,000	–	12,000	–	1.49%	–
CVS	New	CVS Health Corporation	$7,640,000	–	79,800	–	1.44%	–
BAX	New	Baxter International Inc.	$7,507,000	–	166,000	–	1.41%	–
INCY	New	Incyte Corporation	$7,278,000	–	91,000	–	1.37%	–
SHPG	New	Shire PLCsponsored adr	$7,152,000	–	38,850	–	1.35%	–
EW	New	Edwards Lifesciences Corporation	$6,782,000	–	68,000	–	1.28%	–
ABMD	New	Abiomed Inc	$6,251,000	–	57,200	–	1.18%	–
CI	New	Cigna Corporation	$6,144,000	–	48,000	–	1.16%	–
JNJ	New	Johnson & Johnson	$6,065,000	–	50,000	–	1.14%	–
BCR	New	C.R. Bard, Inc.	$5,879,000	–	25,000	–	1.11%	–
ALXN	New	Alexion Pharmaceuticals, Inc.	$5,768,000	–	49,400	–	1.08%	–
AMSG	New	Amsurg Corp	$5,738,000	–	74,000	–	1.08%	–
VRTX	New	Vertex Pharmaceuticals Incorporated	$5,677,000	–	66,000	–	1.07%	–
HUM	New	Humana, Inc.	$5,396,000	–	30,000	–	1.02%	–
MYL	New	Mylan Inc.	$5,176,000	–	119,700	–	0.97%	–
CHRS	New	Coherus BioSciences, Inc	$5,135,000	–	304,000	–	0.97%	–
BMRN	New	BioMarin Pharmaceutical Inc.	$5,057,000	–	65,000	–	0.95%	–
ESRX	New	Express Scripts Holding Company	$4,927,000	–	65,000	–	0.93%	–
MCK	New	McKesson Corporation	$4,853,000	–	26,000	–	0.91%	–
MDVN	New	Medivation, Inc.	$4,703,000	–	78,000	–	0.88%	–
STJ	New	St. Jude Medical, Inc.	$4,680,000	–	60,000	–	0.88%	–
COO	New	Cooper Companies Inc.	$4,032,000	–	23,500	–	0.76%	–
PRGO	New	Perrigo Company plc	$3,989,000	–	44,000	–	0.75%	–
MASI	New	Masimo Corporation	$3,939,000	–	75,000	–	0.74%	–
ARIA	New	ARIAD Pharmaceuticals, Inc.	$3,658,000	–	495,000	–	0.69%	–
AKRXQ	New	Akorn Inc	$3,618,000	–	127,000	–	0.68%	–
NUVA	New	Nuvasive, Inc.	$3,583,000	–	60,000	–	0.67%	–
CERN	New	Cerner Corporation	$3,516,000	–	60,000	–	0.66%	–
HCA	New	HCA Holdings, Inc.	$3,365,000	–	43,700	–	0.63%	–
SUPN	New	Supernus Pharmaceuticals, Inc.	$3,341,000	–	164,000	–	0.63%	–
ACHN	New	Achillion Pharmaceuticals, Inc.	$3,276,000	–	420,000	–	0.62%	–
AET	New	Aetna Inc.	$3,163,000	–	25,900	–	0.60%	–
TMO	New	Thermo Fisher Scientific Inc.	$2,955,000	–	20,000	–	0.56%	–
MNKKQ	New	Mallinckrodt Pub Ltd Co.	$2,857,000	–	47,000	–	0.54%	–
ALKS	New	Alkermes Public Limited Company	$2,831,000	–	65,500	–	0.53%	–
LLY	New	Lilly Eli & Co.	$2,756,000	–	35,000	–	0.52%	–
SGEN	New	Seattle Genetics, Inc.	$2,748,000	–	68,000	–	0.52%	–
HALO	New	Halozyme Therapeutics, Inc.	$2,744,000	–	318,000	–	0.52%	–
IPXL	New	Impax Laboratories, Inc.	$2,738,000	–	95,000	–	0.52%	–
MRK	New	Merck & Co., Inc.	$2,708,000	–	47,000	–	0.51%	–
NVDQ	New	Novadaq Technologies Inc.	$2,657,000	–	270,000	–	0.50%	–
XENT	New	Intersect Ent, Inc.	$2,655,000	–	205,325	–	0.50%	–
NKTR	New	Nektar Therapeutics	$2,647,000	–	186,000	–	0.50%	–
NBIX	New	Neurocrine Biosciences, Inc.	$2,636,000	–	58,000	–	0.50%	–
IONS	New	Ionis Pharmaceuticals Inc.	$2,515,000	–	108,000	–	0.47%	–
NVAX	New	Novavax, Inc.	$2,363,000	–	325,000	–	0.44%	–
MGNX	New	Macrogenics, Inc.	$2,240,000	–	83,000	–	0.42%	–
IBB	New	iSHARES Trustnasdaq biotec etf	$2,187,000	–	8,500	–	0.41%	–
ANGO	New	AngioDynamics, Inc.	$2,176,000	–	151,400	–	0.41%	–
GMED	New	Globus Medical, Inc.cl a	$2,090,000	–	87,700	–	0.39%	–
QGEN	New	Qiagen NV	$1,996,000	–	91,500	–	0.38%	–
HZNP	New	Horizon Pharma plc	$1,927,000	–	117,000	–	0.36%	–
ICPT	New	Intercept Pharmaceuticals, Inc.	$1,926,000	–	13,500	–	0.36%	–
ANTM	New	Anthem, Inc.	$1,839,000	–	14,000	–	0.35%	–
TFX	New	Teleflex Incorporated	$1,775,000	–	10,010	–	0.33%	–
PFE	New	Pfizer Inc.	$1,761,000	–	50,000	–	0.33%	–
BMY	New	Bristol-Myers Squibb Company	$1,692,000	–	23,000	–	0.32%	–
VAR	New	Varian Medical Systems, Inc.	$1,645,000	–	20,000	–	0.31%	–
ZLTQ	New	Zeltiq Aesthetics Inc.	$1,640,000	–	60,000	–	0.31%	–
HCSG	New	Healthcare Services Group Inc.	$1,577,000	–	38,100	–	0.30%	–
LABU	New	Direxion SHS ETF TRsp biotech bl new	$1,557,000	–	55,175	–	0.29%	–
AGIO	New	Agios Pharmaceuticals, Inc.	$1,508,000	–	36,000	–	0.28%	–
RDUS	New	Radius Health Inc.	$1,470,000	–	40,000	–	0.28%	–
ACAD	New	Acadia Pharmaceuticals, Inc.	$1,461,000	–	45,000	–	0.28%	–
INO	New	Inovio Pharmaceuticals, Inc.	$1,432,000	–	155,000	–	0.27%	–
JUNO	New	Juno Therapeutics, Inc.	$1,422,000	–	37,000	–	0.27%	–
RARE	New	Ultragenyx Pharmaceuticals Inc.	$1,369,000	–	28,000	–	0.26%	–
ALNY	New	Alnylam Pharmaceuticals Inc.	$1,332,000	–	24,000	–	0.25%	–
EXEL	New	Exelixis, Inc.	$1,328,000	–	170,000	–	0.25%	–
BLUE	New	Bluebird Bio, Inc.	$1,255,000	–	29,000	–	0.24%	–
ALR	New	Alere Inc	$1,250,000	–	30,000	–	0.24%	–
WMGI	New	Wright Med Group N V	$1,221,000	–	70,309	–	0.23%	–
PRTA	New	Prothena Corporation plc	$1,084,000	–	31,000	–	0.20%	–
LH	New	Laboratory Corporation of America Holdings	$1,042,000	–	8,000	–	0.20%	–
AACH	New	AAC Hldgs Inc	$1,027,000	–	45,000	–	0.19%	–
DVA	New	Davita Healthcare Partners, Inc.	$1,005,000	–	13,000	–	0.19%	–
EVHC	New	Envision Healthcare Hldgs Inc.	$989,000	–	39,000	–	0.19%	–
ABBV	New	Abbvie Inc.	$929,000	–	15,000	–	0.18%	–
CPHD	New	Cepheid Inc.	$923,000	–	30,000	–	0.17%	–
ALDR	New	Alder Biopharmaceuticals Inc.	$824,000	–	33,000	–	0.16%	–
ENDP	New	Endo International PLC	$811,000	–	52,000	–	0.15%	–
BIB	New	ProShares Trust	$796,000	–	20,500	–	0.15%	–
QTNT	New	Quotient Limited	$775,000	–	100,000	–	0.15%	–
CLDX	New	Celldex Therapeutics, Inc.	$702,000	–	160,000	–	0.13%	–
KITE	New	Kite Pharma, Inc.	$700,000	–	14,000	–	0.13%	–
UTHR	New	United Therapeutics Corporation	$667,000	–	6,300	–	0.13%	–
TMH	New	Team Health Holdings Inc.	$610,000	–	15,000	–	0.12%	–
CYH	New	Community Health Systems, Inc.	$603,000	–	50,000	–	0.11%	–
NVRO	New	Nevro Corp.	$553,000	–	7,500	–	0.10%	–
RMD	New	ResMed Inc.	$506,000	–	8,000	–	0.10%	–
PODD	New	Insulet Corporation	$454,000	–	15,000	–	0.08%	–
MYGN	New	Myriad Genetics, Inc.	$428,000	–	14,000	–	0.08%	–
ESPR	New	Esperion Therapeutics Inc.	$395,000	–	40,000	–	0.07%	–
PEN	New	Penumbra, Inc.	$298,000	–	5,000	–	0.06%	–
THC	New	Tenet Healthcare Corporation	$276,000	–	10,000	–	0.05%	–
SGRY	New	Surgery Partners, Inc.	$269,000	–	15,000	–	0.05%	–
TBPH	New	Theravance Biopharma, Inc.	$259,000	–	11,428	–	0.05%	–
HTWR	New	Heartware International, Inc.	$220,000	–	3,813	–	0.04%	–
INFI	New	Infinity Pharmaceuticals, Inc.	$213,000	–	160,000	–	0.04%	–
QHCCQ	New	Quorum Health Corp	$134,000	–	12,500	–	0.02%	–
ZFGN	New	Zafgen, Inc.	$120,000	–	20,000	–	0.02%	–
TTPH	New	Tetraphase Pharmaceuticals, Inc.	$95,000	–	22,000	–	0.02%	–
EIGR	New	Eiger BioPharmaceuticals, Inc.	$66,000	–	3,333	–	0.01%	–

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