$6.41 Billion is the total value of Avoro Capital Advisors LLC's 46 reported holdings in Q3 2023. The portfolio turnover from Q2 2023 to Q3 2023 was 30.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HZNP | HORIZON THERAPEUTICS PLC | $809,830,000 | +12.5% | 7,000,000 | 0.0% | 12.63% | +29.3% | |
| UTHR | Sell | UNITED THERAPEUTICS CORP | $644,294,175 | +0.3% | 2,852,500 | -2.0% | 10.05% | +15.3% |
| ARGX | Sell | ARGENX SEsponsored adr | $491,630,000 | -0.2% | 1,000,000 | -20.9% | 7.67% | +14.8% |
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $487,910,500 | -7.9% | 4,025,000 | -13.0% | 7.61% | +5.8% |
| APLS | APELLIS PHARMACEUTICALS INC | $422,666,662 | -58.2% | 11,111,111 | 0.0% | 6.59% | -52.0% | |
| SGEN | SEAGEN INC | $373,300,413 | +10.2% | 1,759,606 | 0.0% | 5.82% | +26.8% | |
| ASND | Buy | ASCENDIS PHARMAsponsored adr | $343,658,800 | +7.5% | 3,670,000 | +2.5% | 5.36% | +23.6% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $340,648,000 | -1.8% | 3,850,000 | -3.8% | 5.31% | +12.9% |
| FOLD | AMICUS THERAPEUTICS INC | $333,184,000 | -3.2% | 27,400,000 | 0.0% | 5.20% | +11.3% | |
| KRYS | Buy | KRYSTAL BIOTECH INC | $297,604,380 | -1.0% | 2,565,555 | +0.2% | 4.64% | +13.8% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $290,399,971 | +44.7% | 6,666,666 | +20.0% | 4.53% | +66.4% |
| MDGL | Buy | MADRIGAL PHARMACEUTICALS INC | $227,092,200 | -35.1% | 1,555,000 | +2.6% | 3.54% | -25.4% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $179,067,758 | -14.7% | 1,011,111 | -8.5% | 2.79% | -1.9% |
| XENE | XENON PHARMACEUTICALS INC | $167,384,000 | -11.3% | 4,900,000 | 0.0% | 2.61% | +2.0% | |
| CBAY | CYMABAY THERAPEUTICS INC | $153,573,000 | +36.2% | 10,300,000 | 0.0% | 2.40% | +56.5% | |
| Buy | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $113,999,943 | +29.6% | 1,999,999 | +15.9% | 1.78% | +49.0% | |
| BCRX | Sell | BIOCRYST PHARMACEUTICALS INC | $81,774,000 | -3.6% | 11,550,000 | -4.2% | 1.28% | +10.8% |
| Sell | ROIVANT SCIENCES LTD | $54,325,572 | -7.2% | 4,651,162 | -19.9% | 0.85% | +6.7% | |
| KYMR | KYMERA THERAPEUTICS INC | $53,584,500 | -39.5% | 3,855,000 | 0.0% | 0.84% | -30.4% | |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL INC | $53,475,000 | +54.6% | 1,500,000 | +100.0% | 0.83% | +77.8% |
| New | STRUCTURE THERAPEUTICS INCsponsored adr | $50,420,000 | – | 1,000,000 | +100.0% | 0.79% | – | |
| Sell | NUVALENT INC | $37,350,625 | -44.6% | 812,500 | -49.2% | 0.58% | -36.3% | |
| MNKD | Sell | MANNKIND CORP | $37,170,000 | +0.4% | 9,000,000 | -1.1% | 0.58% | +15.5% |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $37,106,659 | -33.1% | 2,555,555 | -3.6% | 0.58% | -23.0% |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | $30,485,000 | -35.4% | 6,700,000 | 0.0% | 0.48% | -25.8% | |
| AKRO | New | AKERO THERAPEUTICS ORD | $28,099,972 | – | 555,555 | +100.0% | 0.44% | – |
| KURA | Sell | KURA ONCOLOGY INC | $27,177,600 | -17.3% | 2,980,000 | -4.0% | 0.42% | -4.9% |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $25,612,500 | – | 1,250,000 | +100.0% | 0.40% | – |
| MARINUS PHARMACEUTICALS INC | $25,357,500 | -25.9% | 3,150,000 | 0.0% | 0.40% | -14.7% | ||
| Buy | TANGO THERAPEUTICS INC | $25,022,220 | +359.6% | 2,222,222 | +35.5% | 0.39% | +427.0% | |
| GLUE | MONTE ROSA THERAPEUTICS INC | $21,722,650 | -30.1% | 4,535,000 | 0.0% | 0.34% | -19.5% | |
| CERE | New | CEREVEL THERAPEUTICS HLDNG | $20,859,766 | – | 955,555 | +100.0% | 0.32% | – |
| PMVP | Sell | PMV PHARMACEUTICALS INC | $18,420,000 | -3.8% | 3,000,000 | -2.0% | 0.29% | +10.4% |
| RNA | AVIDITY BIOSCIENCES INC | $16,013,800 | -42.5% | 2,510,000 | 0.0% | 0.25% | -33.9% | |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS INC | $15,181,550 | +19.1% | 565,000 | +58.1% | 0.24% | +37.0% |
| AADI BIOSCIENCES INC | $13,791,106 | -29.2% | 2,849,402 | 0.0% | 0.22% | -18.6% | ||
| TSHA | New | TAYSHA GENE THERAPIES INC | $12,403,000 | – | 3,925,000 | +100.0% | 0.19% | – |
| VRCA | VERRICA PHARMACEUTICALS INC | $11,476,539 | -32.7% | 2,954,064 | 0.0% | 0.18% | -22.5% | |
| MRUS | New | MERUS N V | $10,479,990 | – | 444,444 | +100.0% | 0.16% | – |
| FENC | FENNEC PHARMACEUTICALS INC | $9,012,000 | -14.9% | 1,200,000 | 0.0% | 0.14% | -2.1% | |
| IKNA | IKENA ONCOLOGY INC | $7,101,200 | -34.0% | 1,640,000 | 0.0% | 0.11% | -24.0% | |
| MCRB | SERES THERAPEUTICS INC | $5,950,000 | -50.3% | 2,500,000 | 0.0% | 0.09% | -42.6% | |
| IO BIOTECH INC | $2,837,119 | -29.6% | 2,055,883 | 0.0% | 0.04% | -20.0% | ||
| TALS | TALARIS THERAPEUTICS INC | $1,405,000 | -7.6% | 500,000 | 0.0% | 0.02% | +4.8% | |
| QQQ | New | Invesco QQQ Trustput | $1,220,000 | – | 500,000 | +100.0% | 0.02% | – |
| New | AEGLEA BIOTHERAPEUTICS INC | $140,361 | – | 11,458 | +100.0% | 0.00% | – | |
| AGLE | Exit | AEGLEA BIOTHERAPEUTICS INC | $0 | – | -286,459 | -100.0% | -0.00% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -6,375,000 | -100.0% | -0.28% | – |
| DSGN | Exit | DESIGN THERAPEUTICS INC | $0 | – | -3,500,000 | -100.0% | -0.30% | – |
| Exit | DICE THERAPEUTICS INC | $0 | – | -2,199,342 | -100.0% | -1.39% | – | |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -8,050,000 | -100.0% | -4.30% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| AMICUS THERAPEUTICS INC | 36 | Q3 2023 | 17.9% |
| MIRATI THERAPEUTICS INC. | 35 | Q3 2023 | 17.2% |
| BIOMARIN PHARMACEUTICAL INC | 31 | Q3 2023 | 8.0% |
| SAREPTA THERAPUTICS INC | 28 | Q3 2023 | 14.8% |
| ASCENDIS PHARMA | 28 | Q3 2023 | 9.1% |
| ARGENX SE | 26 | Q3 2023 | 9.5% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
| FENNEC PHARMACEUTICALS INC | 25 | Q3 2023 | 0.4% |
| MADRIGAL PHARMACEUTICALS INC | 22 | Q3 2023 | 7.2% |
| XENON PHARMACEUTICALS INC | 22 | Q3 2023 | 3.3% |
View Avoro Capital Advisors LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| DICE Therapeutics, Inc. | February 14, 2023 | 2,525,555 | 5.3% |
| IOVANCE BIOTHERAPEUTICS, INC. | February 14, 2023 | 7,020,000 | 4.4% |
| IVERIC bio, Inc. | February 14, 2023 | 6,750,000 | 5.0% |
| Kura Oncology, Inc. | February 14, 2023 | 3,105,000 | 4.5% |
| Aadi Bioscience, Inc. | September 26, 2022 | 2,849,402 | 11.7% |
| ARENA PHARMACEUTICALS INC | February 11, 2022 | 1,235,000 | 2.0% |
| AVADEL PHARMACEUTICALS PLC | February 11, 2022 | 1,670,000 | 2.9% |
| FENNEC PHARMACEUTICALS INC. | February 11, 2022 | 1,200,000 | 4.6% |
| POINT Biopharma Global Inc.Sold out | February 11, 2022 | 0 | 0.0% |
View Avoro Capital Advisors LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-23 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Avoro Capital Advisors LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.