$5.06 Billion is the total value of Avoro Capital Advisors LLC's 40 reported holdings in Q2 2022. The portfolio turnover from Q1 2022 to Q2 2022 was 11.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UTHR | Sell | UNITED THERAPEUTICS CORP | $699,851,000 | +28.7% | 2,970,000 | -2.0% | 13.83% | +39.3% |
| ARGX | Buy | ARGENX SEsponsored adr | $479,493,000 | +21.2% | 1,265,555 | +0.8% | 9.48% | +31.2% |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $443,382,000 | -7.7% | 9,805,000 | +3.8% | 8.76% | -0.0% |
| HZNP | Sell | HORIZON THERAPEUTICS PLC | $398,800,000 | -41.7% | 5,000,000 | -23.1% | 7.88% | -36.9% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $372,609,000 | -14.9% | 5,550,555 | +4.2% | 7.36% | -7.9% |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $287,832,000 | +48.3% | 26,800,000 | +30.7% | 5.69% | +60.5% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $272,145,000 | +16.3% | 3,284,000 | +8.2% | 5.38% | +25.9% |
| SGEN | Buy | SEAGEN INC | $269,834,000 | +42.4% | 1,525,000 | +16.0% | 5.33% | +54.2% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $254,114,000 | +3.8% | 3,390,000 | +8.1% | 5.02% | +12.3% |
| ASND | Buy | ASCENDIS PHARMAsponsored adr | $211,484,000 | -18.1% | 2,275,000 | +3.4% | 4.18% | -11.3% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $198,356,000 | -6.6% | 1,360,000 | +4.6% | 3.92% | +1.2% |
| XENE | Sell | XENON PHARMACEUTICALS INC | $149,058,000 | -2.2% | 4,900,000 | -1.7% | 2.94% | +5.9% |
| MDGL | Buy | MADRIGAL PHARMACEUTICALS INC | $109,875,000 | -21.4% | 1,535,000 | +7.7% | 2.17% | -15.0% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $101,789,000 | -33.0% | 9,220,000 | +1.0% | 2.01% | -27.5% |
| KURA | KURA ONCOLOGY INC | $87,984,000 | +14.0% | 4,800,000 | 0.0% | 1.74% | +23.4% | |
| KRYS | Buy | KRYSTAL BIOTECH INC | $70,585,000 | +5.6% | 1,075,000 | +7.0% | 1.40% | +14.3% |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $68,770,000 | +125.6% | 6,500,000 | +246.7% | 1.36% | +144.0% |
| ISEE | Sell | IVERIC BIO INC | $68,494,000 | -43.9% | 7,120,000 | -1.8% | 1.35% | -39.3% |
| XBI | Sell | SPDR SERIES TRUST - S&P BIOTECHetf | $66,843,000 | -75.6% | 900,000 | -70.5% | 1.32% | -73.6% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL INC | $44,745,000 | +167.9% | 750,000 | +226.1% | 0.88% | +189.8% |
| PMVP | Buy | PMV PHARMACEUTICALS INC | $44,175,000 | -3.6% | 3,100,000 | +40.9% | 0.87% | +4.4% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $42,756,000 | +10.8% | 2,222,222 | +0.1% | 0.84% | +19.9% |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $34,881,000 | +28.6% | 7,550,000 | +11.0% | 0.69% | +39.2% |
| MNKD | Buy | MANNKIND CORP | $34,671,000 | +7.1% | 9,100,000 | +3.4% | 0.68% | +15.9% |
| GLUE | Buy | MONTE ROSA THERAPEUTICS INC | $32,023,000 | -31.0% | 3,311,536 | +0.0% | 0.63% | -25.4% |
| DSGN | DESIGN THERAPEUTICS INC | $31,111,000 | -13.3% | 2,222,222 | 0.0% | 0.62% | -6.1% | |
| CBAY | CYMABAY THERAPEUTICS INC | $30,385,000 | -5.1% | 10,300,000 | 0.0% | 0.60% | +2.6% | |
| KYMR | Buy | KYMERA THERAPEUTICS INC | $24,809,000 | -28.2% | 1,260,000 | +54.3% | 0.49% | -22.3% |
| AADI BIOSCIENCES INC | $22,538,000 | -27.4% | 1,829,402 | 0.0% | 0.44% | -21.5% | ||
| RNA | AVIDITY BIOSCIENCES INC | $18,889,000 | -21.3% | 1,300,000 | 0.0% | 0.37% | -14.8% | |
| DICE THERAPEUTICS INC | $16,684,000 | -18.9% | 1,075,000 | 0.0% | 0.33% | -12.0% | ||
| MARINUS PHARMACEUTICALS INC | $15,246,000 | -48.2% | 3,150,000 | 0.0% | 0.30% | -44.1% | ||
| NUVALENT INC | $14,231,000 | -2.4% | 1,049,471 | 0.0% | 0.28% | +5.6% | ||
| IO BIOTECH INC | $9,601,000 | +0.2% | 2,055,883 | 0.0% | 0.19% | +8.6% | ||
| AMRN | AMARIN CORP PLCsponsored adr | $8,940,000 | -54.7% | 6,000,000 | 0.0% | 0.18% | -50.8% | |
| TANGO THERAPEUTICS INC | $7,022,000 | -40.2% | 1,550,000 | 0.0% | 0.14% | -35.0% | ||
| FENC | FENNEC PHARMACEUTICALS INC | $6,780,000 | +0.9% | 1,200,000 | 0.0% | 0.13% | +8.9% | |
| RLAY | New | RELAY THERAPEUTICS INC | $6,700,000 | – | 400,000 | +100.0% | 0.13% | – |
| AMTI | APPLIED MOLECULAR TRANS INC | $2,997,000 | -61.3% | 1,030,000 | 0.0% | 0.06% | -58.2% | |
| GNCA | GENOCEA BIOSCIENCES INC | $86,000 | -98.6% | 5,084,184 | 0.0% | 0.00% | -98.3% | |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -6,950,000 | -100.0% | -0.17% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCsponsored adr | $0 | – | -1,670,000 | -100.0% | -0.21% | – |
| PRAX | Exit | PRAXIS PRECISION MEDICINES INC | $0 | – | -2,150,000 | -100.0% | -0.40% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -2,275,000 | -100.0% | -1.01% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-08-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| AMICUS THERAPEUTICS INC | 36 | Q3 2023 | 17.9% |
| MIRATI THERAPEUTICS INC. | 35 | Q3 2023 | 17.2% |
| BIOMARIN PHARMACEUTICAL INC | 31 | Q3 2023 | 8.0% |
| SAREPTA THERAPUTICS INC | 28 | Q3 2023 | 14.8% |
| ASCENDIS PHARMA | 28 | Q3 2023 | 9.1% |
| ARGENX SE | 26 | Q3 2023 | 9.5% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
| FENNEC PHARMACEUTICALS INC | 25 | Q3 2023 | 0.4% |
| MADRIGAL PHARMACEUTICALS INC | 22 | Q3 2023 | 7.2% |
| XENON PHARMACEUTICALS INC | 22 | Q3 2023 | 3.3% |
View Avoro Capital Advisors LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| DICE Therapeutics, Inc. | February 14, 2023 | 2,525,555 | 5.3% |
| IOVANCE BIOTHERAPEUTICS, INC. | February 14, 2023 | 7,020,000 | 4.4% |
| IVERIC bio, Inc. | February 14, 2023 | 6,750,000 | 5.0% |
| Kura Oncology, Inc. | February 14, 2023 | 3,105,000 | 4.5% |
| Aadi Bioscience, Inc. | September 26, 2022 | 2,849,402 | 11.7% |
| ARENA PHARMACEUTICALS INC | February 11, 2022 | 1,235,000 | 2.0% |
| AVADEL PHARMACEUTICALS PLC | February 11, 2022 | 1,670,000 | 2.9% |
| FENNEC PHARMACEUTICALS INC. | February 11, 2022 | 1,200,000 | 4.6% |
| POINT Biopharma Global Inc.Sold out | February 11, 2022 | 0 | 0.0% |
View Avoro Capital Advisors LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-23 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Avoro Capital Advisors LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.