Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | APOGEE THERAPEUTICS INC | $180,907,737 | – | 8,493,321 | – | 19.04% | – | |
| New | RAYZEBIO INC | $89,174,003 | – | 4,016,847 | – | 9.39% | – | |
| COGT | Buy | COGENT BIOSCIENCES INC | $45,670,628 | -17.7% | 4,684,167 | +0.0% | 4.81% | -45.8% |
| TSHA | New | TAYSHA GENE THERAPIES INC | $45,644,443 | – | 14,444,444 | – | 4.80% | – |
| Buy | ENLIVEN THERAPEUTICS INC | $40,363,961 | -11.3% | 2,954,902 | +32.5% | 4.25% | -41.6% | |
| PHVS | Buy | PHARVARIS N V | $32,630,516 | +62.5% | 1,563,513 | +17.9% | 3.44% | +7.0% |
| CABA | Buy | CABALETTA BIO INC | $30,032,911 | +17.9% | 1,973,253 | +0.0% | 3.16% | -22.4% |
| GHRS | Sell | GH RESEARCH PLCordinary shares | $27,578,456 | -33.9% | 2,744,125 | -22.0% | 2.90% | -56.5% |
| New | HILLEVAX INC | $27,401,860 | – | 2,037,313 | – | 2.88% | – | |
| SVRA | Buy | SAVARA INC | $27,158,790 | +33.8% | 7,184,865 | +13.1% | 2.86% | -11.9% |
| AMAM | Sell | AMBRX BIOPHARMA INCsponsored ads | $23,805,000 | -41.8% | 2,070,000 | -16.7% | 2.51% | -61.7% |
| TVTX | New | TRAVERE THERAPEUTICS INC | $23,455,672 | – | 2,623,677 | – | 2.47% | – |
| TERN | Buy | TERNS PHARMACEUTICALS INC | $15,554,133 | -40.2% | 3,092,273 | +4.0% | 1.64% | -60.6% |
| MRSN | New | MERSANA THERAPEUTICS INC | $14,386,560 | – | 11,328,000 | – | 1.51% | – |
| New | DIANTHUS THERAPEUTICS INC | $12,681,741 | – | 927,706 | – | 1.34% | – | |
| ADVM | Buy | ADVERUM BIOTECHNOLOGIES INC | $9,859,950 | +59.6% | 6,573,300 | +69.1% | 1.04% | +5.1% |
| New | ACELYRIN INC | $8,790,256 | – | 864,332 | – | 0.92% | – | |
| New | SAGIMET BIOSCIENCES INC | $4,532,000 | – | 515,000 | – | 0.48% | – | |
| AGLE | Sell | AEGLEA BIOTHERAPEUTICS INC | $3,614,167 | +26.5% | 295,034 | -95.3% | 0.38% | -16.8% |
| OLMA | New | OLEMA PHARMACEUTICALS INC | $951,469 | – | 77,042 | – | 0.10% | – |
| Exit | AVALO THERAPEUTICS INC | $0 | – | -1,250,000 | – | -0.07% | – | |
| BDTX | Exit | BLACK DIAMOND THERAPEUTICS I | $0 | – | -353,629 | – | -0.29% | – |
| Exit | THESEUS PHARMACEUTICALS INC | $0 | – | -770,000 | – | -1.15% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $73,335,577 | – | 3,082,622 | – | 11.73% | – |
| COGT | New | COGENT BIOSCIENCES INC | $55,460,123 | – | 4,684,132 | – | 8.87% | – |
| FDMT | New | 4D MOLECULAR THERAPEUTICS IN | $54,210,000 | – | 3,000,000 | – | 8.67% | – |
| New | ENLIVEN THERAPEUTICS INC | $45,516,892 | – | 2,230,127 | – | 7.28% | – | |
| MRUS | New | MERUS N V | $45,451,215 | – | 1,726,214 | – | 7.27% | – |
| GHRS | New | GH RESEARCH PLCordinary shares | $41,730,688 | – | 3,517,125 | – | 6.67% | – |
| AMAM | New | AMBRX BIOPHARMA INCsponsored ads | $40,902,442 | – | 2,484,960 | – | 6.54% | – |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $26,250,003 | – | 2,916,667 | – | 4.20% | – |
| TERN | New | TERNS PHARMACEUTICALS INC | $26,012,604 | – | 2,972,869 | – | 4.16% | – |
| CABA | New | CABALETTA BIO INC | $25,474,670 | – | 1,973,251 | – | 4.07% | – |
| DYN | New | DYNE THERAPEUTICS INC | $24,456,521 | – | 2,173,913 | – | 3.91% | – |
| CELC | New | CELCUITY INC | $23,117,138 | – | 2,105,386 | – | 3.70% | – |
| SVRA | New | SAVARA INC | $20,293,142 | – | 6,351,531 | – | 3.24% | – |
| PHVS | New | PHARVARIS N V | $20,078,668 | – | 1,326,200 | – | 3.21% | – |
| RYTM | New | RHYTHM PHARMACEUTICALS INC | $17,974,100 | – | 1,090,000 | – | 2.87% | – |
| ORIC | New | ORIC PHARMACEUTICALS INC | $16,628,563 | – | 2,142,856 | – | 2.66% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $10,792,619 | – | 1,040,754 | – | 1.73% | – |
| TRVI | New | TREVI THERAPEUTICS INC | $8,179,529 | – | 3,422,397 | – | 1.31% | – |
| APLT | New | APPLIED THERAPEUTICS INC | $7,242,284 | – | 5,658,034 | – | 1.16% | – |
| New | THESEUS PHARMACEUTICALS INC | $7,184,100 | – | 770,000 | – | 1.15% | – | |
| MIST | New | MILESTONE PHARMACEUTICALS IN | $6,295,114 | – | 2,208,812 | – | 1.01% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $6,179,131 | – | 3,886,246 | – | 0.99% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $6,100,072 | – | 5,304,410 | – | 0.98% | – |
| PLRX | New | PLIANT THERAPEUTICS INC | $5,235,756 | – | 288,949 | – | 0.84% | – |
| LYRA | New | LYRA THERAPEUTICS INC | $3,798,339 | – | 924,170 | – | 0.61% | – |
| AGLE | New | AEGLEA BIOTHERAPEUTICS INC | $2,857,621 | – | 6,343,221 | – | 0.46% | – |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $1,785,826 | – | 353,629 | – | 0.29% | – |
| New | RALLYBIO CORP | $1,519,891 | – | 268,532 | – | 0.24% | – | |
| AFMD | New | AFFIMED N V | $854,571 | – | 1,428,571 | – | 0.14% | – |
| New | AVALO THERAPEUTICS INC | $444,000 | – | 1,250,000 | – | 0.07% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CLDX | Exit | Celldex Therapeutics Inc | $0 | – | -75,000 | – | -0.32% | – |
| AFMD | Exit | Affimed NV | $0 | – | -1,428,571 | – | -0.45% | – |
| Exit | Rallybio Corp | $0 | – | -268,532 | – | -0.60% | – | |
| LIFE | Exit | aTyr Pharma Inc | $0 | – | -1,398,889 | – | -0.65% | – |
| IMCR | Exit | Immunocore Holdings PLCads | $0 | – | -94,605 | – | -0.68% | – |
| LYRA | Exit | Lyra Therapeutics Inc | $0 | – | -924,170 | – | -0.71% | – |
| TRVI | Exit | Trevi Therapeutics Inc | $0 | – | -3,050,022 | – | -0.72% | – |
| ALT | Exit | Altimmune Inc | $0 | – | -369,306 | – | -0.73% | – |
| PRVB | Exit | Provention Bio Inc | $0 | – | -1,118,653 | – | -0.78% | – |
| SVRA | Exit | Savara Inc | $0 | – | -4,555,038 | – | -1.09% | – |
| RXDX | Exit | Prometheus Biosciences Inc | $0 | – | -121,663 | – | -1.11% | – |
| Exit | Ventyx Biosciences Inc | $0 | – | -207,925 | – | -1.12% | – | |
| INZY | Exit | Inozyme Pharma Inc | $0 | – | -2,709,987 | – | -1.12% | – |
| FULC | Exit | Fulcrum Therapeutics Inc | $0 | – | -1,200,000 | – | -1.50% | – |
| Exit | LianBiospons adr | $0 | – | -5,378,341 | – | -1.66% | – | |
| AVTE | Exit | Aerovate Therapeutics Inc | $0 | – | -833,927 | – | -2.13% | – |
| Exit | Dice Therapeutics Inc | $0 | – | -764,979 | – | -2.39% | – | |
| AKUS | Exit | Akouos Inc | $0 | – | -2,800,566 | – | -2.92% | – |
| TIL | Exit | Instil Bio Inc | $0 | – | -4,105,779 | – | -3.07% | – |
| ANNX | Exit | Annexon Inc | $0 | – | -3,220,050 | – | -3.07% | – |
| GOSS | Exit | Gossamer Bio Inc | $0 | – | -1,747,000 | – | -3.23% | – |
| Exit | Marinus Pharmaceuticals Inc | $0 | – | -3,156,803 | – | -3.24% | – | |
| TERN | Exit | Terns Pharmaceuticals Inc | $0 | – | -3,707,891 | – | -3.37% | – |
| MIST | Exit | Milestone Pharmaceuticals Inc | $0 | – | -2,425,737 | – | -3.44% | – |
| PLRX | Exit | Pliant Therapeutics Inc | $0 | – | -1,080,000 | – | -3.48% | – |
| GHRS | Exit | GH Research PLCord sh | $0 | – | -3,333,154 | – | -5.98% | – |
| VRDN | Exit | Viridian Therapeutics Inc | $0 | – | -2,130,308 | – | -6.74% | – |
| RLMD | Exit | Relmada Therapeutics Inc | $0 | – | -1,518,056 | – | -8.67% | – |
| COGT | Exit | Cogent Biosciences Inc | $0 | – | -4,038,117 | – | -9.30% | – |
| ACRS | Exit | Aclaris Therapeutics Inc | $0 | – | -4,563,962 | – | -11.08% | – |
| TCDA | Exit | Tricida Inc | $0 | – | -9,050,064 | – | -14.64% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TCDA | Buy | Tricida Inc | $94,845,000 | +37.4% | 9,050,064 | +26.9% | 14.64% | +7.6% |
| RLMD | Sell | Relmada Therapeutics Inc | $56,198,000 | +30.4% | 1,518,056 | -33.1% | 8.67% | +2.1% |
| VRDN | Buy | Viridian Therapeutics Inc | $43,693,000 | +103.8% | 2,130,308 | +15.0% | 6.74% | +59.7% |
| GHRS | Buy | GH Research PLCord sh | $38,731,000 | +21.8% | 3,333,154 | +4.6% | 5.98% | -4.6% |
| PLRX | New | Pliant Therapeutics Inc | $22,561,000 | – | 1,080,000 | – | 3.48% | – |
| MIST | New | Milestone Pharmaceuticals Inc | $22,293,000 | – | 2,425,737 | – | 3.44% | – |
| TERN | New | Terns Pharmaceuticals Inc | $21,839,000 | – | 3,707,891 | – | 3.37% | – |
| GOSS | New | Gossamer Bio Inc | $20,929,000 | – | 1,747,000 | – | 3.23% | – |
| ANNX | Buy | Annexon Inc | $19,900,000 | +173.7% | 3,220,050 | +67.0% | 3.07% | +114.5% |
| TIL | Sell | Instil Bio Inc | $19,872,000 | -28.3% | 4,105,779 | -31.5% | 3.07% | -43.8% |
| AKUS | Buy | Akouos Inc | $18,932,000 | +51.3% | 2,800,566 | +5.0% | 2.92% | +18.6% |
| New | Dice Therapeutics Inc | $15,514,000 | – | 764,979 | – | 2.39% | – | |
| AVTE | Buy | Aerovate Therapeutics Inc | $13,827,000 | +49.8% | 833,927 | +41.2% | 2.13% | +17.4% |
| FULC | New | Fulcrum Therapeutics Inc | $9,708,000 | – | 1,200,000 | – | 1.50% | – |
| New | Ventyx Biosciences Inc | $7,259,000 | – | 207,925 | – | 1.12% | – | |
| RXDX | New | Prometheus Biosciences Inc | $7,179,000 | – | 121,663 | – | 1.11% | – |
| SVRA | Buy | Savara Inc | $7,060,000 | +12.8% | 4,555,038 | +10.6% | 1.09% | -11.7% |
| IMCR | New | Immunocore Holdings PLCads | $4,441,000 | – | 94,605 | – | 0.68% | – |
| CLDX | Sell | Celldex Therapeutics Inc | $2,108,000 | -91.0% | 75,000 | -91.3% | 0.32% | -92.9% |
| XENE | Exit | Xenon Pharmaceuticals Inc | $0 | – | -30,000 | – | -0.18% | – |
| KDNY | Exit | Chinook Therapeutics Inc | $0 | – | -489,618 | – | -1.69% | – |
| Exit | Aadi Bioscience Inc | $0 | – | -1,173,518 | – | -2.85% | – | |
| VTGN | Exit | VistaGen Therapeutics Inc | $0 | – | -20,697,286 | – | -3.59% | – |
| TVTX | Exit | Travere Therapeutics Inc | $0 | – | -1,711,102 | – | -8.16% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TCDA | New | Tricida Inc | $69,039,000 | – | 7,132,079 | – | 13.60% | – |
| ACRS | New | Aclaris Therapeutics Inc | $63,713,000 | – | 4,563,962 | – | 12.55% | – |
| RLMD | New | Relmada Therapeutics Inc | $43,109,000 | – | 2,270,072 | – | 8.49% | – |
| TVTX | New | Travere Therapeutics Inc | $41,460,000 | – | 1,711,102 | – | 8.16% | – |
| COGT | New | Cogent Biosciences Inc | $36,424,000 | – | 4,038,117 | – | 7.17% | – |
| GHRS | New | GH Research PLCord sh | $31,792,000 | – | 3,185,573 | – | 6.26% | – |
| TIL | New | Instil Bio Inc | $27,709,000 | – | 5,997,657 | – | 5.46% | – |
| CLDX | New | Celldex Therapeutics Inc | $23,324,000 | – | 865,116 | – | 4.59% | – |
| VRDN | New | Viridian Therapeutics Inc | $21,438,000 | – | 1,852,919 | – | 4.22% | – |
| VTGN | New | VistaGen Therapeutics Inc | $18,214,000 | – | 20,697,286 | – | 3.59% | – |
| New | Marinus Pharmaceuticals Inc | $15,279,000 | – | 3,156,803 | – | 3.01% | – | |
| New | Aadi Bioscience Inc | $14,458,000 | – | 1,173,518 | – | 2.85% | – | |
| INZY | New | Inozyme Pharma Inc | $12,927,000 | – | 2,709,987 | – | 2.55% | – |
| AKUS | New | Akouos Inc | $12,509,000 | – | 2,667,119 | – | 2.46% | – |
| New | LianBiospons adr | $11,617,000 | – | 5,378,341 | – | 2.29% | – | |
| AVTE | New | Aerovate Therapeutics Inc | $9,228,000 | – | 590,408 | – | 1.82% | – |
| TRVI | New | Trevi Therapeutics Inc | $8,571,000 | – | 3,050,022 | – | 1.69% | – |
| KDNY | New | Chinook Therapeutics Inc | $8,563,000 | – | 489,618 | – | 1.69% | – |
| ANNX | New | Annexon Inc | $7,270,000 | – | 1,928,477 | – | 1.43% | – |
| SVRA | New | Savara Inc | $6,259,000 | – | 4,117,530 | – | 1.23% | – |
| LYRA | New | Lyra Therapeutics Inc | $5,222,000 | – | 924,170 | – | 1.03% | – |
| PRVB | New | Provention Bio Inc | $4,475,000 | – | 1,118,653 | – | 0.88% | – |
| ALT | New | Altimmune Inc | $4,321,000 | – | 369,306 | – | 0.85% | – |
| LIFE | New | aTyr Pharma Inc | $3,959,000 | – | 1,398,889 | – | 0.78% | – |
| AFMD | New | Affimed NV | $3,957,000 | – | 1,428,571 | – | 0.78% | – |
| New | Rallybio Corp | $2,027,000 | – | 268,532 | – | 0.40% | – | |
| XENE | New | Xenon Pharmaceuticals Inc | $913,000 | – | 30,000 | – | 0.18% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -19,495 | – | -0.04% | – |
| TCDA | Exit | TRICIDA INC | $0 | – | -390,707 | – | -0.23% | – |
| Exit | ASTRIA THERAPEUTICS INC | $0 | – | -538,999 | – | -0.61% | – | |
| AKYA | Exit | AKOYA BIOSCIENCES INC | $0 | – | -400,000 | – | -0.72% | – |
| CVRX | Exit | CVRX INC | $0 | – | -533,370 | – | -1.13% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -1,088,817 | – | -1.18% | – |
| PHVS | Exit | PHARVARIS NV | $0 | – | -552,882 | – | -1.26% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -1,196,196 | – | -1.44% | – |
| LIFE | Exit | ATYR PHARMA INC | $0 | – | -1,565,000 | – | -1.82% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -706,050 | – | -2.05% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -3,427,461 | – | -2.13% | – |
| Exit | NUVALENT INC | $0 | – | -803,951 | – | -2.33% | – | |
| CNTA | Exit | CENTESSA PHARMACEUTICALS PLCspons adr | $0 | – | -1,127,272 | – | -2.42% | – |
| GRPH | Exit | GRAPHITE BIO INC | $0 | – | -1,612,617 | – | -3.40% | – |
| Exit | MARINUS PHARMACEUTICALS INC | $0 | – | -2,641,809 | – | -3.86% | – | |
| KNTE | Exit | KINNATE BIOPHARMA INC | $0 | – | -1,473,014 | – | -4.36% | – |
| GHRS | Exit | GH RESEARCH PLCord sh | $0 | – | -1,642,296 | – | -4.65% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -1,387,720 | – | -4.67% | – |
| TVTX | Exit | TRAVERE THERAPEUTICS INC | $0 | – | -1,732,410 | – | -5.40% | – |
| OLMA | Exit | OLEMA PHARMACEUTICALS INC | $0 | – | -1,536,193 | – | -5.44% | – |
| ALT | Exit | ALTIMMUNE INC | $0 | – | -3,800,000 | – | -5.52% | – |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -16,047,286 | – | -5.65% | – |
| Exit | AADI BIOSCIENCE INC | $0 | – | -1,529,402 | – | -5.77% | – | |
| CLDX | Exit | CELLDEX THERAPEUTICS INC | $0 | – | -1,098,174 | – | -7.62% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -4,563,962 | – | -10.55% | – |
| TIL | Exit | INSTIL BIO INC | $0 | – | -6,865,076 | – | -15.76% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CLDX | Sell | CELLDEX THERAPEUTICS INC | $59,290,000 | +42.9% | 1,098,174 | -11.5% | 7.62% | +51.3% |
| New | AADI BIOSCIENCE INC | $44,919,000 | – | 1,529,402 | – | 5.77% | – | |
| ALT | Buy | ALTIMMUNE INC | $42,978,000 | +24.7% | 3,800,000 | +8.6% | 5.52% | +32.0% |
| TVTX | New | TRAVERE THERAPEUTICS INC | $42,011,000 | – | 1,732,410 | – | 5.40% | – |
| GHRS | Buy | GH RESEARCH PLCord sh | $36,229,000 | +30.7% | 1,642,296 | +28.7% | 4.65% | +38.4% |
| New | NUVALENT INC | $18,129,000 | – | 803,951 | – | 2.33% | – | |
| CRVS | New | CORVUS PHARMACEUTICALS INC | $16,589,000 | – | 3,427,461 | – | 2.13% | – |
| CGEM | Sell | CULLINAN ONCOLOGY INC | $15,936,000 | -36.6% | 706,050 | -27.7% | 2.05% | -32.9% |
| LIFE | New | ATYR PHARMA INC | $14,210,000 | – | 1,565,000 | – | 1.82% | – |
| ATHA | Sell | ATHIRA PHARMA INC | $11,220,000 | -26.2% | 1,196,196 | -19.4% | 1.44% | -21.9% |
| PHVS | Sell | PHARVARIS NV | $9,803,000 | -41.7% | 552,882 | -38.8% | 1.26% | -38.3% |
| CVRX | Sell | CVRX INC | $8,822,000 | -50.3% | 533,370 | -15.8% | 1.13% | -47.3% |
| New | ASTRIA THERAPEUTICS INC | $4,765,000 | – | 538,999 | – | 0.61% | – | |
| TCDA | New | TRICIDA INC | $1,813,000 | – | 390,707 | – | 0.23% | – |
| ACET | Exit | ADICET BIO INC | $0 | – | -183,702 | – | -0.23% | – |
| Exit | CATABASIS PHARMACEUTICALS INC | $0 | – | -3,234,000 | – | -0.83% | – | |
| HARP | Exit | HARPOON THERAPEUTICS INC | $0 | – | -512,005 | – | -0.86% | – |
| ALGS | Exit | ALIGOS THERAPEUTICS INC | $0 | – | -408,377 | – | -1.01% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -272,306 | – | -1.40% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -575,000 | – | -1.45% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -391,000 | – | -1.51% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -625,754 | – | -2.17% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -2,001,686 | – | -2.36% | – | |
| PRVB | Exit | PROVENTION BIO INC | $0 | – | -2,902,744 | – | -2.97% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TIL | New | INSTIL BIO INC | $132,633,000 | – | 6,865,076 | – | 16.09% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $80,143,000 | – | 4,563,962 | – | 9.72% | – |
| VTGN | New | VISTAGEN THERAPEUTICS INC | $50,549,000 | – | 16,047,286 | – | 6.13% | – |
| GRPH | New | GRAPHITE BIO INC | $49,556,000 | – | 1,612,617 | – | 6.01% | – |
| New | MARINUS PHARMACEUTICALS INC | $47,394,000 | – | 2,641,809 | – | 5.75% | – | |
| RLMD | New | RELMADA THERAPEUTICS INC | $44,421,000 | – | 1,387,720 | – | 5.39% | – |
| OLMA | New | OLEMA PHARMACEUTICALS INC | $42,983,000 | – | 1,536,193 | – | 5.21% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC | $41,486,000 | – | 1,240,610 | – | 5.03% | – |
| ALT | New | ALTIMMUNE INC | $34,475,000 | – | 3,500,000 | – | 4.18% | – |
| KNTE | New | KINNATE BIOPHARMA INC | $34,292,000 | – | 1,473,014 | – | 4.16% | – |
| GHRS | New | GH RESEARCH PLCord sh | $27,724,000 | – | 1,275,831 | – | 3.36% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $25,136,000 | – | 976,145 | – | 3.05% | – |
| CNTA | New | CENTESSA PHARMACEUTICALS PLCspons ads | $25,037,000 | – | 1,127,272 | – | 3.04% | – |
| PRVB | New | PROVENTION BIO INC | $24,470,000 | – | 2,902,744 | – | 2.97% | – |
| New | TRILLIUM THERAPEUTICS INC | $19,416,000 | – | 2,001,686 | – | 2.36% | – | |
| EPIX | New | ESSA PHARMA INC | $17,878,000 | – | 625,754 | – | 2.17% | – |
| CVRX | New | CVRX INC | $17,734,000 | – | 633,370 | – | 2.15% | – |
| PHVS | New | PHARVARIS NV | $16,821,000 | – | 902,882 | – | 2.04% | – |
| ATHA | New | ATHIRA PHARMA INC | $15,206,000 | – | 1,485,005 | – | 1.84% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $12,430,000 | – | 391,000 | – | 1.51% | – |
| KURA | New | KURA ONCOLOGY INC | $11,989,000 | – | 575,000 | – | 1.45% | – |
| KROS | New | KEROS THERAPEUTICS INC | $11,565,000 | – | 272,306 | – | 1.40% | – |
| COGT | New | COGENT BIOSCIENCES INC | $8,830,000 | – | 1,088,817 | – | 1.07% | – |
| ALGS | New | ALIGOS THERAPEUTICS INC | $8,325,000 | – | 408,377 | – | 1.01% | – |
| AKYA | New | AKOYA BIOSCIENCES INC | $7,736,000 | – | 400,000 | – | 0.94% | – |
| HARP | New | HARPOON THERAPEUTICS INC | $7,102,000 | – | 512,005 | – | 0.86% | – |
| New | CATABASIS PHARMACEUTICALS INC | $6,824,000 | – | 3,234,000 | – | 0.83% | – | |
| ACET | New | ADICET BIO INC | $1,890,000 | – | 183,702 | – | 0.23% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $357,000 | – | 19,495 | – | 0.04% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MDNA | Exit | MEDICENNA THERAPEUTICS CORP | $0 | – | -92,453 | – | -0.08% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -51,653 | – | -0.09% | – |
| TSHA | Exit | TAYSHA GENE THERAPIES INC | $0 | – | -107,982 | – | -0.51% | – |
| BCTG | Exit | BCTG ACQUISITION CORP | $0 | – | -500,000 | – | -1.01% | – |
| FSDC | Exit | FS DEVELOPMENT CORP-A | $0 | – | -500,000 | – | -1.10% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -625,710 | – | -1.81% | – |
| UMRX | Exit | UNUM THERAPEUTICS INC | $0 | – | -4,355,273 | – | -1.99% | – |
| ALXO | Exit | ALX ONCOLOGY HOLDINGS INC | $0 | – | -300,000 | – | -2.22% | – |
| MTCR | Exit | METACRINE INC | $0 | – | -1,143,673 | – | -2.28% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC | $0 | – | -800,000 | – | -2.32% | – |
| MRNS | Exit | MARINUS PHARMACEUTICALS INC | $0 | – | -1,192,883 | – | -3.00% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -575,000 | – | -3.45% | – |
| IMV | Exit | IMV INC | $0 | – | -4,000,000 | – | -3.47% | – |
| CRDF | Exit | CARDIFF ONCOLOGY INC | $0 | – | -1,271,985 | – | -3.53% | – |
| HGEN | Exit | HUMANIGEN INC | $0 | – | -2,332,516 | – | -4.86% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -668,440 | – | -4.92% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -672,306 | – | -5.07% | – |
| SURF | Exit | SURFACE ONCOLOGY INC | $0 | – | -3,877,895 | – | -5.23% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -1,521,623 | – | -5.50% | – |
| ALT | Exit | ALTIMMUNE INC | $0 | – | -4,500,000 | – | -11.62% | – |
| CNST | Exit | CONSTELLATION PHARMACEUTICAL | $0 | – | -4,016,873 | – | -15.92% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -7,204,577 | – | -20.03% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Buy | TRILLIUM THERAPEUTICS INC | $102,377,000 | +86.4% | 7,204,577 | +6.1% | 20.03% | +52.3% | |
| ATHA | New | ATHIRA PHARMA INC | $28,089,000 | – | 1,521,623 | – | 5.50% | – |
| HGEN | New | HUMANIGEN INC | $24,818,000 | – | 2,332,516 | – | 4.86% | – |
| CRDF | New | CARDIFF ONCOLOGY INC | $18,049,000 | – | 1,271,985 | – | 3.53% | – |
| IMV | New | IMV INC | $17,760,000 | – | 4,000,000 | – | 3.47% | – |
| MRNS | Sell | MARINUS PHARMACEUTICALS INC | $15,329,000 | +5.4% | 1,192,883 | -79.2% | 3.00% | -13.9% |
| CLDX | New | CELLDEX THERAPEUTICS INC | $11,864,000 | – | 800,000 | – | 2.32% | – |
| MTCR | New | METACRINE INC | $11,677,000 | – | 1,143,673 | – | 2.28% | – |
| ALXO | New | ALX ONCOLOGY HOLDINGS INC | $11,322,000 | – | 300,000 | – | 2.22% | – |
| UMRX | New | UNUM THERAPEUTICS INC | $10,191,000 | – | 4,355,273 | – | 1.99% | – |
| FSDC | New | FS DEVELOPMENT CORP-A | $5,599,000 | – | 500,000 | – | 1.10% | – |
| BCTG | New | BCTG ACQUISITION CORP | $5,180,000 | – | 500,000 | – | 1.01% | – |
| TSHA | New | TAYSHA GENE THERAPIES INC | $2,598,000 | – | 107,982 | – | 0.51% | – |
| GRTX | New | GALERA THERAPEUTICS INC | $467,000 | – | 51,653 | – | 0.09% | – |
| MDNA | New | MEDICENNA THERAPEUTICS CORP | $383,000 | – | 92,453 | – | 0.08% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -378,888 | – | -1.10% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -291,140 | – | -1.39% | – |
| ADAP | Exit | ADAPTIMMUNE THERAPEUTICSspons adr | $0 | – | -781,940 | – | -1.87% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCspons adr | $0 | – | -1,057,827 | – | -2.05% | – |
| NARI | Exit | INARI MEDICAL INC | $0 | – | -235,000 | – | -2.73% | – |
| MYOV | Exit | MYOVANT SCIENCES LTD | $0 | – | -845,000 | – | -4.17% | – |
| VXRT | Exit | VAXART INC | $0 | – | -2,765,000 | – | -5.86% | – |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CNST | New | CONSTELLATION PHARMACEUTICALS INC | $120,707,000 | – | 4,016,873 | – | 28.90% | – |
| New | TRILLIUM THERAPEUTICS INC | $54,931,000 | – | 6,790,000 | – | 13.15% | – | |
| ALT | New | ALTIMMUNE INC | $48,195,000 | – | 4,500,000 | – | 11.54% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $29,913,000 | – | 668,440 | – | 7.16% | – |
| SURF | New | SURFACE ONCOLOGY INC | $25,439,000 | – | 3,877,895 | – | 6.09% | – |
| KROS | New | KEROS THERAPEUTICS INC | $25,218,000 | – | 672,306 | – | 6.04% | – |
| VXRT | New | VAXART INC | $24,470,000 | – | 2,765,000 | – | 5.86% | – |
| MYOV | New | MYOVANT SCIENCES LTD | $17,424,000 | – | 845,000 | – | 4.17% | – |
| MRNS | New | MARINUS PHARMACEUTICALS INC | $14,545,000 | – | 5,726,540 | – | 3.48% | – |
| NARI | New | INARI MEDICAL INC | $11,383,000 | – | 235,000 | – | 2.73% | – |
| KURA | New | KURA ONCOLOGY INC | $9,373,000 | – | 575,000 | – | 2.24% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $9,273,000 | – | 625,710 | – | 2.22% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCspons adr | $8,547,000 | – | 1,057,827 | – | 2.05% | – |
| ADAP | New | ADAPTIMMUNE THERAPEUTICSspons adr | $7,827,000 | – | 781,940 | – | 1.87% | – |
| ETNB | New | 89BIO INC | $5,802,000 | – | 291,140 | – | 1.39% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $4,585,000 | – | 378,888 | – | 1.10% | – |