Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LABU | Buy | DIREXION SHS ETF TRsp biotch bl new | $3,086,000 | -37.5% | 99,855 | +1.4% | 5.58% | -23.7% |
| SGEN | Buy | SEATTLE GENETICS INC | $1,539,000 | +24.2% | 18,020 | +0.7% | 2.78% | +51.7% |
| ILMN | Buy | ILLUMINA INC | $1,436,000 | -17.0% | 4,721 | +0.5% | 2.60% | +1.4% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $1,403,000 | -6.6% | 8,279 | +1.0% | 2.54% | +14.1% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $1,100,000 | +13.5% | 13,684 | +2.5% | 1.99% | +38.6% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $973,000 | -25.2% | 9,933 | +0.1% | 1.76% | -8.6% |
| FBIO | Buy | FORTRESS BIOTECH INC | $865,000 | +146.4% | 613,551 | +162.2% | 1.56% | +201.2% |
| INCY | Buy | INCYTE CORP | $791,000 | -12.3% | 10,659 | +0.4% | 1.43% | +7.0% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $677,000 | -2.6% | 2,439 | +9.8% | 1.22% | +19.0% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $654,000 | -18.8% | 9,700 | +3.2% | 1.18% | -0.8% |
| AMRN | Buy | AMARIN CORP PLCspons adr new | $510,000 | +57.9% | 33,641 | +102.2% | 0.92% | +92.9% |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $432,000 | +35.0% | 12,005 | +0.2% | 0.78% | +65.1% |
| AMGN | Buy | AMGEN INC | $294,000 | +14.4% | 1,518 | +8.7% | 0.53% | +39.7% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $282,000 | +11.0% | 3,127 | +3.8% | 0.51% | +35.6% |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $279,000 | – | 3,498 | – | 0.50% | – |
| ICPT | Sell | INTERCEPT PHARMACEUTICALS IN | $261,000 | -44.1% | 3,926 | -33.1% | 0.47% | -31.7% |
| LGND | Buy | LIGAND PHARMACEUTICALS INC | $242,000 | +0.4% | 2,428 | +15.0% | 0.44% | +22.4% |
| NKTR | Buy | NEKTAR THERAPEUTICS | $235,000 | -47.2% | 12,927 | +3.4% | 0.42% | -35.4% |
| EXEL | Buy | EXELIXIS INC | $232,000 | -4.9% | 13,132 | +14.8% | 0.42% | +16.1% |
| ALKS | New | ALKERMES PLC | $227,000 | – | 11,632 | – | 0.41% | – |
| FGEN | Buy | FIBROGEN INC | $212,000 | -4.1% | 5,742 | +17.6% | 0.38% | +17.1% |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -4,806 | – | -0.36% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -6,116 | – | -0.51% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -3,570 | – | -0.55% | – |
| VKTX | Exit | VIKING THERAPEUTICS INC | $0 | – | -48,485 | – | -0.60% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -36,731 | – | -0.68% | – |
| PCRX | Exit | PACIRA BIOSCIENCES | $0 | – | -11,250 | – | -0.72% | – |
| INSM | Exit | INSMED INC | $0 | – | -26,936 | – | -1.02% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -5,840 | – | -1.10% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -5,353 | – | -1.20% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -62,575 | – | -1.28% | – |
Q2 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IBB | New | ISHARES TRnasdaq biotech | $13,638,000 | – | 125,000 | – | 20.18% | – |
| IBB | New | ISHARES TRcall | $9,274,000 | – | 85,000 | – | 13.72% | – |
| LABU | New | DIREXION SHS ETF TRsp biotch bl new | $4,940,000 | – | 98,432 | – | 7.31% | – |
| MTD | New | METTLER TOLEDO INTERNATIONAL | $2,717,000 | – | 3,235 | – | 4.02% | – |
| ILMN | New | ILLUMINA INC | $1,730,000 | – | 4,699 | – | 2.56% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $1,502,000 | – | 8,193 | – | 2.22% | – |
| BMY | New | BRISTOL MYERS SQUIBB CO | $1,497,000 | – | 33,000 | – | 2.22% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $1,300,000 | – | 9,927 | – | 1.92% | – |
| IONS | New | IONIS PHARMACEUTICALS INC | $1,293,000 | – | 20,124 | – | 1.91% | – |
| PRQR | New | PROQR THRAPEUTICS N V | $1,260,000 | – | 138,461 | – | 1.86% | – |
| SGEN | New | SEATTLE GENETICS INC | $1,239,000 | – | 17,901 | – | 1.83% | – |
| QGEN | New | QIAGEN NV | $1,170,000 | – | 28,858 | – | 1.73% | – |
| QURE | New | UNIQURE NV | $1,111,000 | – | 14,215 | – | 1.64% | – |
| EXAS | New | EXACT SCIENCES CORP | $1,007,000 | – | 8,534 | – | 1.49% | – |
| ONCE | New | SPARK THERAPEUTICS INC | $993,000 | – | 9,699 | – | 1.47% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $969,000 | – | 13,351 | – | 1.43% | – |
| INCY | New | INCYTE CORP | $902,000 | – | 10,613 | – | 1.34% | – |
| IMMU | New | IMMUNOMEDICS INC | $868,000 | – | 62,575 | – | 1.28% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $813,000 | – | 5,353 | – | 1.20% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $805,000 | – | 9,400 | – | 1.19% | – |
| BLUE | New | BLUEBIRD BIO INC | $743,000 | – | 5,840 | – | 1.10% | – |
| ASND | New | ASCENDIS PHARMA A Ssponsored adr | $713,000 | – | 6,190 | – | 1.06% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $695,000 | – | 2,221 | – | 1.03% | – |
| INSM | New | INSMED INC | $690,000 | – | 26,936 | – | 1.02% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $656,000 | – | 17,339 | – | 0.97% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $640,000 | – | 6,780 | – | 0.95% | – |
| GTHX | New | G1 THERAPEUTICS INC | $639,000 | – | 20,844 | – | 0.94% | – |
| GWPH | New | GW PHARMACEUTICALS PLCads | $633,000 | – | 3,674 | – | 0.94% | – |
| EPZM | New | EPIZYME INC | $632,000 | – | 50,378 | – | 0.94% | – |
| CRSP | New | CRISPR THERAPEUTICS AGnamen akt | $622,000 | – | 13,214 | – | 0.92% | – |
| ARNA | New | ARENA PHARMACEUTICALS INC | $573,000 | – | 9,770 | – | 0.85% | – |
| CELG | New | CELGENE CORP | $520,000 | – | 5,625 | – | 0.77% | – |
| MGNX | New | MACROGENICS INC | $510,000 | – | 30,075 | – | 0.76% | – |
| GBT | New | GLOBAL BLOOD THERAPEUTICS IN | $499,000 | – | 9,479 | – | 0.74% | – |
| PCRX | New | PACIRA BIOSCIENCES | $489,000 | – | 11,250 | – | 0.72% | – |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $475,000 | – | 10,852 | – | 0.70% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $467,000 | – | 5,872 | – | 0.69% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $466,000 | – | 28,490 | – | 0.69% | – |
| ZGNX | New | ZOGENIX INC | $465,000 | – | 9,725 | – | 0.69% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $458,000 | – | 36,731 | – | 0.68% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $445,000 | – | 12,503 | – | 0.66% | – |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $420,000 | – | 18,631 | – | 0.62% | – |
| VKTX | New | VIKING THERAPEUTICS INC | $402,000 | – | 48,485 | – | 0.60% | – |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $374,000 | – | 3,570 | – | 0.55% | – |
| FBIO | New | FORTRESS BIOTECH INC | $351,000 | – | 234,030 | – | 0.52% | – |
| ANAB | New | ANAPTYSBIO INC | $345,000 | – | 6,116 | – | 0.51% | – |
| CKPT | New | CHECKPOINT THERAPEUTICS INC | $342,000 | – | 112,760 | – | 0.51% | – |
| AMRN | New | AMARIN CORP PLCspons adr new | $323,000 | – | 16,641 | – | 0.48% | – |
| TECH | New | BIO TECHNE CORP | $323,000 | – | 1,551 | – | 0.48% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $322,000 | – | 5,064 | – | 0.48% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $320,000 | – | 11,981 | – | 0.47% | – |
| IQV | New | IQVIA HLDGS INC | $319,000 | – | 1,985 | – | 0.47% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $300,000 | – | 2,112 | – | 0.44% | – |
| GRFS | New | GRIFOLS S Asp adr rep b nvt | $278,000 | – | 13,196 | – | 0.41% | – |
| GILD | New | GILEAD SCIENCES INC | $276,000 | – | 4,082 | – | 0.41% | – |
| BIIB | New | BIOGEN INC | $263,000 | – | 1,123 | – | 0.39% | – |
| AMGN | New | AMGEN INC | $257,000 | – | 1,397 | – | 0.38% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $254,000 | – | 3,012 | – | 0.38% | – |
| EXEL | New | EXELIXIS INC | $244,000 | – | 11,440 | – | 0.36% | – |
| LGND | New | LIGAND PHARMACEUTICALS INC | $241,000 | – | 2,111 | – | 0.36% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $240,000 | – | 4,806 | – | 0.36% | – |
| FGEN | New | FIBROGEN INC | $221,000 | – | 4,883 | – | 0.33% | – |
| REPH | New | RECRO PHARMA INC | $115,000 | – | 11,353 | – | 0.17% | – |
Q4 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SCYX | Exit | SCYNEXIS INC | $0 | – | -29,974 | – | -0.09% | – |
| REPH | Exit | RECRO PHARMA INC | $0 | – | -11,353 | – | -0.19% | – |
| CFRX | Exit | CONTRAFECT CORP | $0 | – | -67,500 | – | -0.33% | – |
| PRTK | Exit | PARATEK PHARMACEUTICALS INC | $0 | – | -18,000 | – | -0.42% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -1,945 | – | -0.68% | – |
| EXEL | Exit | EXELIXIS INC | $0 | – | -16,475 | – | -0.70% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -4,533 | – | -0.84% | – |
| GRFS | Exit | GRIFOLS S Asp adr rep b nvt | $0 | – | -16,445 | – | -0.84% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -2,805 | – | -0.86% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -1,032 | – | -0.87% | – |
| FBIO | Exit | FORTRESS BIOTECH INC | $0 | – | -234,030 | – | -0.89% | – |
| CRL | Exit | CHARLES RIV LABS INTL INC | $0 | – | -2,826 | – | -0.91% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -1,841 | – | -0.91% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -45,004 | – | -0.95% | – |
| CKPT | Exit | CHECKPOINT THERAPEUTICS INC | $0 | – | -112,760 | – | -0.96% | – |
| XON | Exit | INTREXON CORP | $0 | – | -23,780 | – | -0.98% | – |
| IQV | Exit | IQVIA HLDGS INC | $0 | – | -3,156 | – | -0.98% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -120,150 | – | -0.99% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -3,391 | – | -1.00% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -20,828 | – | -1.03% | – |
| TECH | Exit | BIO TECHNE CORP | $0 | – | -2,242 | – | -1.09% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -6,134 | – | -1.12% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -3,998 | – | -1.21% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -11,250 | – | -1.32% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -11,803 | – | -1.72% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -12,345 | – | -2.04% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -9,747 | – | -2.08% | – |
| ADMS | Exit | ADAMAS PHARMACEUTICALS INC | $0 | – | -44,500 | – | -2.13% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -9,854 | – | -2.28% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -2,531 | – | -2.44% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -17,138 | – | -2.48% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -6,210 | – | -2.53% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -25,242 | – | -2.56% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS IN | $0 | – | -308,569 | – | -2.71% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -15,102 | – | -2.78% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -13,499 | – | -2.82% | – |
| QGEN | Exit | QIAGEN NV | $0 | – | -31,620 | – | -2.86% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -23,293 | – | -2.87% | – |
| SGEN | Exit | SEATTLE GENETICS INC | $0 | – | -19,288 | – | -3.55% | – |
| MEIP | Exit | MEI PHARMA INC | $0 | – | -360,000 | – | -3.70% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -8,727 | – | -4.02% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -12,847 | – | -4.26% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -4,972 | – | -4.36% | – |
| MTD | Exit | METTLER TOLEDO INTERNATIONAL | $0 | – | -3,235 | – | -4.70% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -82,430 | – | -5.78% | – |
| PRQR | Exit | PROQR THRAPEUTICS N V | $0 | – | -138,461 | – | -6.40% | – |
| TSRO | Exit | TESARO INC | $0 | – | -94,300 | – | -8.78% | – |
Q3 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TSRO | Buy | TESARO INC | $3,679,000 | +620.0% | 94,300 | +720.0% | 8.78% | +692.7% |
| PRQR | Sell | PROQR THRAPEUTICS N V | $2,679,000 | +138.6% | 138,461 | -10.0% | 6.40% | +162.7% |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $2,421,000 | +309.6% | 82,430 | +534.1% | 5.78% | +350.9% |
| MTD | Sell | METTLER TOLEDO INTERNATIONAL | $1,970,000 | -5.3% | 3,235 | -10.0% | 4.70% | +4.3% |
| ILMN | Sell | ILLUMINA INC | $1,825,000 | +22.1% | 4,972 | -7.1% | 4.36% | +34.4% |
| ALXN | Sell | ALEXION PHARMACEUTICALS INC | $1,786,000 | +4.8% | 12,847 | -6.5% | 4.26% | +15.3% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $1,682,000 | +6.1% | 8,727 | -6.5% | 4.02% | +16.7% |
| MEIP | Sell | MEI PHARMA INC | $1,552,000 | -1.5% | 360,000 | -10.0% | 3.70% | +8.4% |
| SGEN | Sell | SEATTLE GENETICS INC | $1,487,000 | +7.5% | 19,288 | -7.4% | 3.55% | +18.4% |
| IONS | Sell | IONIS PHARMACEUTICALS INC | $1,201,000 | +20.5% | 23,293 | -2.6% | 2.87% | +32.6% |
| QGEN | Sell | QIAGEN NV | $1,198,000 | +1.3% | 31,620 | -3.4% | 2.86% | +11.5% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $1,181,000 | -15.0% | 13,499 | -4.3% | 2.82% | -6.5% |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $1,165,000 | -12.7% | 15,102 | -4.6% | 2.78% | -3.9% |
| ACHN | New | ACHILLION PHARMACEUTICALS IN | $1,136,000 | – | 308,569 | – | 2.71% | – |
| ALKS | Sell | ALKERMES PLC | $1,071,000 | +1.8% | 25,242 | -1.2% | 2.56% | +12.1% |
| LOXO | Sell | LOXO ONCOLOGY INC | $1,061,000 | -11.4% | 6,210 | -10.0% | 2.53% | -2.4% |
| FGEN | Sell | FIBROGEN INC | $1,041,000 | -9.7% | 17,138 | -7.0% | 2.48% | -0.6% |
| REGN | Sell | REGENERON PHARMACEUTICALS | $1,023,000 | +9.9% | 2,531 | -6.2% | 2.44% | +21.0% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $956,000 | -1.8% | 9,854 | -4.7% | 2.28% | +8.0% |
| ADMS | Buy | ADAMAS PHARMACEUTICALS INC | $891,000 | +130.2% | 44,500 | +196.7% | 2.13% | +153.5% |
| CELG | Buy | CELGENE CORP | $872,000 | +13.0% | 9,747 | +0.2% | 2.08% | +24.4% |
| INCY | Buy | INCYTE CORP | $853,000 | +3.3% | 12,345 | +0.2% | 2.04% | +13.7% |
| NKTR | Buy | NEKTAR THERAPEUTICS | $720,000 | +72.7% | 11,803 | +38.3% | 1.72% | +90.2% |
| PCRX | Sell | PACIRA PHARMACEUTICALS INC | $553,000 | +37.9% | 11,250 | -10.0% | 1.32% | +51.7% |
| RARE | Sell | ULTRAGENYX PHARMACEUTICAL IN | $468,000 | -3.5% | 6,134 | -2.8% | 1.12% | +6.2% |
| TECH | Buy | BIO TECHNE CORP | $458,000 | +62.4% | 2,242 | +17.6% | 1.09% | +78.6% |
| ACAD | Buy | ACADIA PHARMACEUTICALS INC | $432,000 | +84.6% | 20,828 | +35.9% | 1.03% | +103.4% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $417,000 | +38.5% | 3,391 | +10.6% | 1.00% | +52.5% |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $415,000 | -2.8% | 120,150 | -10.0% | 0.99% | +7.0% |
| IQV | Buy | IQVIA HLDGS INC | $409,000 | +47.1% | 3,156 | +13.2% | 0.98% | +61.9% |
| XON | Buy | INTREXON CORP | $409,000 | +66.9% | 23,780 | +35.3% | 0.98% | +83.8% |
| AKBA | Sell | AKEBIA THERAPEUTICS INC | $397,000 | -20.4% | 45,004 | -10.0% | 0.95% | -12.4% |
| AMGN | Sell | AMGEN INC | $382,000 | -65.1% | 1,841 | -69.0% | 0.91% | -61.6% |
| CRL | Buy | CHARLES RIV LABS INTL INC | $380,000 | +23.8% | 2,826 | +3.4% | 0.91% | +36.2% |
| FBIO | New | FORTRESS BIOTECH INC | $374,000 | – | 234,030 | – | 0.89% | – |
| BIIB | Sell | BIOGEN INC | $365,000 | -64.4% | 1,032 | -70.8% | 0.87% | -60.8% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $359,000 | +19.3% | 2,805 | +5.5% | 0.86% | +31.2% |
| GRFS | Buy | GRIFOLS S Asp adr rep b nvt | $351,000 | +31.0% | 16,445 | +32.2% | 0.84% | +44.2% |
| GILD | Buy | GILEAD SCIENCES INC | $350,000 | +16.3% | 4,533 | +6.6% | 0.84% | +28.0% |
| EXEL | Buy | EXELIXIS INC | $292,000 | 0.0% | 16,475 | +21.5% | 0.70% | +10.1% |
| BLUE | Buy | BLUEBIRD BIO INC | $284,000 | +10.9% | 1,945 | +19.3% | 0.68% | +22.2% |
| PRTK | Sell | PARATEK PHARMACEUTICALS INC | $175,000 | -14.2% | 18,000 | -10.0% | 0.42% | -5.4% |
| CFRX | Sell | CONTRAFECT CORP | $140,000 | -15.7% | 67,500 | -10.0% | 0.33% | -7.2% |
| REPH | Sell | RECRO PHARMA INC | $81,000 | +28.6% | 11,353 | -10.0% | 0.19% | +40.9% |
| SCYX | Sell | SCYNEXIS INC | $36,000 | -34.5% | 29,974 | -10.0% | 0.09% | -27.7% |
| PGNX | Exit | PROGENICS PHARMACEUTICALS IN | $0 | – | -10,891 | – | -0.19% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -7,000 | – | -0.56% | – |
| IBB | Exit | ISHARES TRnasdaq biotech | $0 | – | -18,750 | – | -4.46% | – |
| BIB | Exit | PROSHARES TR | $0 | – | -93,805 | – | -11.64% | – |
| XBI | Exit | SPDR SERIES TRUSTs&p biotech | $0 | – | -58,000 | – | -11.97% | – |
Q2 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | New | SPDR SERIES TRUSTs&p biotech | $5,521,000 | – | 58,000 | – | 11.97% | – |
| BIB | New | PROSHARES TR | $5,366,000 | – | 93,805 | – | 11.64% | – |
| MTD | New | METTLER TOLEDO INTERNATIONAL | $2,080,000 | – | 3,594 | – | 4.51% | – |
| IBB | New | ISHARES TRnasdaq biotech | $2,059,000 | – | 18,750 | – | 4.46% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $1,705,000 | – | 13,734 | – | 3.70% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $1,586,000 | – | 9,331 | – | 3.44% | – |
| MEIP | New | MEI PHARMA INC | $1,576,000 | – | 400,000 | – | 3.42% | – |
| ILMN | New | ILLUMINA INC | $1,495,000 | – | 5,352 | – | 3.24% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $1,390,000 | – | 14,112 | – | 3.02% | – |
| SGEN | New | SEATTLE GENETICS INC | $1,383,000 | – | 20,834 | – | 3.00% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $1,334,000 | – | 15,833 | – | 2.89% | – |
| LOXO | New | LOXO ONCOLOGY INC | $1,197,000 | – | 6,900 | – | 2.60% | – |
| QGEN | New | QIAGEN NV | $1,183,000 | – | 32,720 | – | 2.57% | – |
| FGEN | New | FIBROGEN INC | $1,153,000 | – | 18,423 | – | 2.50% | – |
| PRQR | New | PROQR THRAPEUTICS N V | $1,123,000 | – | 153,846 | – | 2.44% | – |
| AMGN | New | AMGEN INC | $1,095,000 | – | 5,930 | – | 2.38% | – |
| ALKS | New | ALKERMES PLC | $1,052,000 | – | 25,552 | – | 2.28% | – |
| BIIB | New | BIOGEN INC | $1,025,000 | – | 3,532 | – | 2.22% | – |
| IONS | New | IONIS PHARMACEUTICALS INC | $997,000 | – | 23,916 | – | 2.16% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $974,000 | – | 10,336 | – | 2.11% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $931,000 | – | 2,698 | – | 2.02% | – |
| INCY | New | INCYTE CORP | $826,000 | – | 12,321 | – | 1.79% | – |
| CELG | New | CELGENE CORP | $772,000 | – | 9,724 | – | 1.67% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $591,000 | – | 13,000 | – | 1.28% | – |
| TSRO | New | TESARO INC | $511,000 | – | 11,500 | – | 1.11% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $499,000 | – | 50,004 | – | 1.08% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $485,000 | – | 6,311 | – | 1.05% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $427,000 | – | 133,500 | – | 0.93% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $417,000 | – | 8,532 | – | 0.90% | – |
| PCRX | New | PACIRA PHARMACEUTICALS INC | $401,000 | – | 12,500 | – | 0.87% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $387,000 | – | 15,000 | – | 0.84% | – |
| CKPT | New | CHECKPOINT THERAPEUTICS INC | $336,000 | – | 112,760 | – | 0.73% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $335,000 | – | 3,998 | – | 0.73% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $307,000 | – | 2,734 | – | 0.67% | – |
| GILD | New | GILEAD SCIENCES INC | $301,000 | – | 4,251 | – | 0.65% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $301,000 | – | 3,065 | – | 0.65% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $301,000 | – | 2,660 | – | 0.65% | – |
| EXEL | New | EXELIXIS INC | $292,000 | – | 13,555 | – | 0.63% | – |
| TECH | New | BIO TECHNE CORP | $282,000 | – | 1,907 | – | 0.61% | – |
| IQV | New | IQVIA HLDGS INC | $278,000 | – | 2,789 | – | 0.60% | – |
| GRFS | New | GRIFOLS S Asp adr rep b nvt | $268,000 | – | 12,442 | – | 0.58% | – |
| MDCO | New | MEDICINES CO | $257,000 | – | 7,000 | – | 0.56% | – |
| BLUE | New | BLUEBIRD BIO INC | $256,000 | – | 1,631 | – | 0.56% | – |
| XON | New | INTREXON CORP | $245,000 | – | 17,580 | – | 0.53% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $234,000 | – | 15,328 | – | 0.51% | – |
| PRTK | New | PARATEK PHARMACEUTICALS INC | $204,000 | – | 20,000 | – | 0.44% | – |
| CFRX | New | CONTRAFECT CORP | $166,000 | – | 75,000 | – | 0.36% | – |
| PGNX | New | PROGENICS PHARMACEUTICALS IN | $88,000 | – | 10,891 | – | 0.19% | – |
| REPH | New | RECRO PHARMA INC | $63,000 | – | 12,615 | – | 0.14% | – |
| SCYX | New | SCYNEXIS INC | $55,000 | – | 33,304 | – | 0.12% | – |
Q4 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PGNX | Exit | PROGENICS PHARMACEUTICALS IN | $0 | – | -21,782 | – | -0.14% | – |
| SCYX | Exit | SCYNEXIS INC | $0 | – | -66,608 | – | -0.14% | – |
| CFRX | Exit | CONTRAFECT CORP | $0 | – | -150,000 | – | -0.15% | – |
| LGND | Exit | LIGAND PHARMACEUTICALS INC | $0 | – | -1,519 | – | -0.19% | – |
| REPH | Exit | RECRO PHARMA INC | $0 | – | -25,231 | – | -0.20% | – |
| AVXS | Exit | AVEXIS INC | $0 | – | -2,500 | – | -0.22% | – |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -15,874 | – | -0.23% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -4,481 | – | -0.23% | – |
| SNR | Exit | NEW SR INVT GROUP INC | $0 | – | -41,850 | – | -0.34% | – |
| AKBA | Exit | AKEBIA THERAPEUTICS INC | $0 | – | -21,009 | – | -0.37% | – |
| XON | Exit | INTREXON CORP | $0 | – | -23,928 | – | -0.41% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -4,108 | – | -0.43% | – |
| CKPT | Exit | CHECKPOINT THERAPEUTICS INC | $0 | – | -112,760 | – | -0.46% | – |
| Q | Exit | QUINTILES IMS HOLDINGS INC | $0 | – | -5,413 | – | -0.46% | – |
| TECH | Exit | BIO TECHNE CORP | $0 | – | -4,268 | – | -0.46% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -14,000 | – | -0.47% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -6,462 | – | -0.47% | – |
| CRL | Exit | CHARLES RIV LABS INTL INC | $0 | – | -4,955 | – | -0.48% | – |
| GRFS | Exit | GRIFOLS S Asp adr rep b nvt | $0 | – | -24,805 | – | -0.49% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -15,639 | – | -0.53% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -9,644 | – | -0.53% | – |
| BIVV | Exit | BIOVERATIV INC | $0 | – | -11,056 | – | -0.57% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -11,899 | – | -0.57% | – |
| ADMS | Exit | ADAMAS PHARMACEUTICALS INC | $0 | – | -30,000 | – | -0.57% | – |
| TSRO | Exit | TESARO INC | $0 | – | -5,000 | – | -0.58% | – |
| JUNO | Exit | JUNO THERAPEUTICS INC | $0 | – | -14,720 | – | -0.59% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -133,500 | – | -0.66% | – |
| GILD | Exit | GILEAD SCIENCES INCcall | $0 | – | -10,000 | – | -0.73% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -25,000 | – | -0.84% | – |
| PRTK | Exit | PARATEK PHARMACEUTICALS INC | $0 | – | -40,000 | – | -0.90% | – |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -100,000 | – | -0.98% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -15,000 | – | -1.11% | – |
| LOXO | Exit | LOXO ONCOLOGY INC | $0 | – | -13,800 | – | -1.14% | – |
| LLY | Exit | LILLY ELI & COcall | $0 | – | -15,000 | – | -1.15% | – |
| LABU | Exit | DIREXION SHS ETF TRsp biotch bl new | $0 | – | -16,002 | – | -1.23% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -11,447 | – | -1.44% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -19,926 | – | -1.66% | – |
| QGEN | Exit | QIAGEN NV | $0 | – | -64,421 | – | -1.82% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -4,561 | – | -1.83% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -6,687 | – | -1.88% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -170,500 | – | -1.89% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -11,406 | – | -1.91% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -33,347 | – | -2.00% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -11,235 | – | -2.01% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -44,183 | – | -2.01% | – |
| SGEN | Exit | SEATTLE GENETICS INC | $0 | – | -41,263 | – | -2.01% | – |
| MTD | Exit | METTLER TOLEDO INTERNATIONAL | $0 | – | -3,594 | – | -2.02% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -20,148 | – | -2.11% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -16,177 | – | -2.12% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -60,000 | – | -2.19% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -48,244 | – | -2.20% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -104,328 | – | -2.25% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -18,274 | – | -2.49% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB COcall | $0 | – | -45,000 | – | -2.57% | – |
| PFE | Exit | PFIZER INC | $0 | – | -112,300 | – | -3.60% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -120,000 | – | -3.65% | – |
| IBB | Exit | ISHARES TRnasdaq biotech | $0 | – | -12,500 | – | -3.74% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INCcall | $0 | – | -35,000 | – | -4.40% | – |
| MRK | Exit | MERCK & CO INC | $0 | – | -83,700 | – | -4.81% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -47,459 | – | -5.00% | – |
| XBI | Exit | SPDR SERIES TRUSTs&p biotech | $0 | – | -65,000 | – | -5.05% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB CO | $0 | – | -90,000 | – | -5.15% | – |
| BIB | Exit | PROSHARES TR | $0 | – | -130,500 | – | -7.17% | – |
Q3 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $5,576,000 | +42.4% | 47,459 | -3.3% | 5.00% | +39.5% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $2,778,000 | +13.5% | 18,274 | -3.8% | 2.49% | +11.1% |
| NKTR | Buy | NEKTAR THERAPEUTICS | $2,504,000 | +31.8% | 104,328 | +7.3% | 2.25% | +29.1% |
| ALKS | Buy | ALKERMES PLC | $2,453,000 | -0.7% | 48,244 | +13.2% | 2.20% | -2.8% |
| CELG | Buy | CELGENE CORP | $2,359,000 | +26.6% | 16,177 | +12.8% | 2.12% | +24.0% |
| INCY | Buy | INCYTE CORP | $2,352,000 | +4.8% | 20,148 | +13.0% | 2.11% | +2.6% |
| SGEN | Buy | SEATTLE GENETICS INC | $2,245,000 | +23.6% | 41,263 | +17.6% | 2.01% | +21.0% |
| IONS | Buy | IONIS PHARMACEUTICALS INC | $2,240,000 | +0.4% | 44,183 | +0.7% | 2.01% | -1.7% |
| ILMN | Buy | ILLUMINA INC | $2,238,000 | +30.1% | 11,235 | +13.3% | 2.01% | +27.4% |
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $2,226,000 | +46.7% | 33,347 | +13.1% | 2.00% | +43.7% |
| AMGN | Buy | AMGEN INC | $2,127,000 | +25.8% | 11,406 | +16.1% | 1.91% | +23.2% |
| BIIB | Buy | BIOGEN INC | $2,094,000 | +33.5% | 6,687 | +15.8% | 1.88% | +30.8% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $2,039,000 | -8.4% | 4,561 | +0.6% | 1.83% | -10.3% |
| QGEN | Buy | QIAGEN NV | $2,029,000 | +6.6% | 64,421 | +13.4% | 1.82% | +4.4% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $1,855,000 | +21.9% | 19,926 | +18.9% | 1.66% | +19.4% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $1,606,000 | +38.6% | 11,447 | +20.2% | 1.44% | +35.7% |
| JUNO | Sell | JUNO THERAPEUTICS INC | $660,000 | +22.9% | 14,720 | -18.1% | 0.59% | +20.3% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $634,000 | +66.0% | 11,899 | +93.3% | 0.57% | +62.6% |
| BIVV | New | BIOVERATIV INC | $631,000 | – | 11,056 | – | 0.57% | – |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $591,000 | +148.3% | 9,644 | +86.4% | 0.53% | +143.1% |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $589,000 | – | 15,639 | – | 0.53% | – |
| GRFS | Buy | GRIFOLS S Asp adr rep b nvt | $543,000 | +99.6% | 24,805 | +92.5% | 0.49% | +95.6% |
| CRL | Buy | CHARLES RIV LABS INTL INC | $535,000 | +106.6% | 4,955 | +93.4% | 0.48% | +102.5% |
| GILD | Buy | GILEAD SCIENCES INC | $524,000 | +127.8% | 6,462 | +98.5% | 0.47% | +122.7% |
| TECH | Buy | BIO TECHNE CORP | $516,000 | +108.1% | 4,268 | +102.1% | 0.46% | +104.0% |
| Q | Buy | QUINTILES IMS HOLDINGS INC | $515,000 | +97.3% | 5,413 | +85.3% | 0.46% | +93.3% |
| CKPT | Sell | CHECKPOINT THERAPEUTICS INC | $507,000 | -4.3% | 112,760 | -4.2% | 0.46% | -6.4% |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $481,000 | – | 4,108 | – | 0.43% | – |
| XON | Buy | INTREXON CORP | $455,000 | +2.9% | 23,928 | +30.4% | 0.41% | +0.7% |
| ICPT | Buy | INTERCEPT PHARMACEUTICALS IN | $260,000 | +18.2% | 4,481 | +146.2% | 0.23% | +15.3% |
| LGND | Sell | LIGAND PHARMACEUTICALS INC | $207,000 | -19.5% | 1,519 | -28.1% | 0.19% | -20.9% |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -29,934 | – | -0.20% | – |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -17,425 | – | -0.37% | – |
| MYGN | Exit | MYRIAD GENETICS INC | $0 | – | -20,414 | – | -0.48% | – |
| KITE | Exit | KITE PHARMA INC | $0 | – | -5,915 | – | -0.56% | – |
| BIB | Exit | PROSHARES TRput | $0 | – | -42,500 | – | -2.08% | – |
| IBB | Exit | ISHARES TRput | $0 | – | -12,500 | – | -3.55% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -65,000 | – | -4.60% | – |
Q2 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BIB | New | PROSHARES TR | $6,969,000 | – | 130,500 | – | 6.38% | – |
| MRK | New | MERCK & CO INC | $5,364,000 | – | 83,700 | – | 4.91% | – |
| XBI | New | SPDR SERIES TRUSTput | $5,017,000 | – | 65,000 | – | 4.60% | – |
| XBI | New | SPDR SERIES TRUSTs&p biotech | $5,017,000 | – | 65,000 | – | 4.60% | – |
| BMY | New | BRISTOL MYERS SQUIBB CO | $5,015,000 | – | 90,000 | – | 4.59% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INCcall | $4,258,000 | – | 35,000 | – | 3.90% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $4,091,000 | – | 120,000 | – | 3.75% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $3,916,000 | – | 49,095 | – | 3.59% | – |
| IBB | New | ISHARES TRnasdq biotec etf | $3,876,000 | – | 12,500 | – | 3.55% | – |
| IBB | New | ISHARES TRput | $3,876,000 | – | 12,500 | – | 3.55% | – |
| PFE | New | PFIZER INC | $3,772,000 | – | 112,300 | – | 3.46% | – |
| GSK | New | GLAXOSMITHKLINE PLCsponsored adr | $2,587,000 | – | 60,000 | – | 2.37% | – |
| BMY | New | BRISTOL MYERS SQUIBB COcall | $2,508,000 | – | 45,000 | – | 2.30% | – |
| ALKS | New | ALKERMES PLC | $2,471,000 | – | 42,623 | – | 2.26% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $2,448,000 | – | 18,994 | – | 2.24% | – |
| BIB | New | PROSHARES TRput | $2,270,000 | – | 42,500 | – | 2.08% | – |
| INCY | New | INCYTE CORP | $2,245,000 | – | 17,832 | – | 2.06% | – |
| IONS | New | IONIS PHARMACEUTICALS INC | $2,232,000 | – | 43,867 | – | 2.04% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $2,226,000 | – | 4,532 | – | 2.04% | – |
| MTD | New | METTLER TOLEDO INTERNATIONAL | $2,115,000 | – | 3,594 | – | 1.94% | – |
| QGEN | New | QIAGEN NV | $1,904,000 | – | 56,796 | – | 1.74% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $1,900,000 | – | 97,199 | – | 1.74% | – |
| CELG | New | CELGENE CORP | $1,863,000 | – | 14,344 | – | 1.71% | – |
| SGEN | New | SEATTLE GENETICS INC | $1,816,000 | – | 35,093 | – | 1.66% | – |
| RXDX | New | IGNYTA INC | $1,765,000 | – | 170,500 | – | 1.62% | – |
| ILMN | New | ILLUMINA INC | $1,720,000 | – | 9,915 | – | 1.58% | – |
| AMGN | New | AMGEN INC | $1,691,000 | – | 9,821 | – | 1.55% | – |
| BIIB | New | BIOGEN INC | $1,568,000 | – | 5,777 | – | 1.44% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $1,522,000 | – | 16,762 | – | 1.39% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $1,517,000 | – | 29,482 | – | 1.39% | – |
| CLVS | New | CLOVIS ONCOLOGY INC | $1,404,000 | – | 15,000 | – | 1.29% | – |
| LLY | New | LILLY ELI & COcall | $1,235,000 | – | 15,000 | – | 1.13% | – |
| PCRX | New | PACIRA PHARMACEUTICALS INC | $1,193,000 | – | 25,000 | – | 1.09% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $1,159,000 | – | 9,526 | – | 1.06% | – |
| LOXO | New | LOXO ONCOLOGY INC | $1,107,000 | – | 13,800 | – | 1.01% | – |
| LABU | New | DIREXION SHS ETF TRsp biotch bl new | $1,009,000 | – | 16,002 | – | 0.92% | – |
| PRTK | New | PARATEK PHARMACEUTICALS INC | $964,000 | – | 40,000 | – | 0.88% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $905,000 | – | 100,000 | – | 0.83% | – |
| AXSM | New | AXSOME THERAPEUTICS INC | $734,000 | – | 133,500 | – | 0.67% | – |
| GILD | New | GILEAD SCIENCES INCcall | $706,000 | – | 10,000 | – | 0.65% | – |
| TSRO | New | TESARO INC | $699,000 | – | 5,000 | – | 0.64% | – |
| KITE | New | KITE PHARMA INC | $613,000 | – | 5,915 | – | 0.56% | – |
| JUNO | New | JUNO THERAPEUTICS INC | $537,000 | – | 17,970 | – | 0.49% | – |
| MDCO | New | MEDICINES CO | $532,000 | – | 14,000 | – | 0.49% | – |
| CKPT | New | CHECKPOINT THERAPEUTICS INC | $530,000 | – | 117,760 | – | 0.49% | – |
| MYGN | New | MYRIAD GENETICS INC | $527,000 | – | 20,414 | – | 0.48% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $525,000 | – | 30,000 | – | 0.48% | – |
| XON | New | INTREXON CORP | $442,000 | – | 18,345 | – | 0.40% | – |
| SNR | New | NEW SR INVT GROUP INC | $421,000 | – | 41,850 | – | 0.39% | – |
| AXGT | New | AXOVANT SCIENCES LTD | $404,000 | – | 17,425 | – | 0.37% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $382,000 | – | 6,157 | – | 0.35% | – |
| AKBA | New | AKEBIA THERAPEUTICS INC | $302,000 | – | 21,009 | – | 0.28% | – |
| GRFS | New | GRIFOLS S Asp adr rep b nvt | $272,000 | – | 12,885 | – | 0.25% | – |
| Q | New | QUINTILES IMS HOLDINGS INC | $261,000 | – | 2,921 | – | 0.24% | – |
| CRL | New | CHARLES RIV LABS INTL INC | $259,000 | – | 2,562 | – | 0.24% | – |
| LGND | New | LIGAND PHARMACEUTICALS INC | $257,000 | – | 2,113 | – | 0.24% | – |
| TECH | New | BIO TECHNE CORP | $248,000 | – | 2,112 | – | 0.23% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $238,000 | – | 5,175 | – | 0.22% | – |
| GILD | New | GILEAD SCIENCES INC | $230,000 | – | 3,256 | – | 0.21% | – |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $220,000 | – | 1,820 | – | 0.20% | – |
| HRTX | New | HERON THERAPEUTICS INC | $220,000 | – | 15,874 | – | 0.20% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $220,000 | – | 29,934 | – | 0.20% | – |
| CFRX | New | CONTRAFECT CORP | $218,000 | – | 150,000 | – | 0.20% | – |
| AVXS | New | AVEXIS INC | $205,000 | – | 2,500 | – | 0.19% | – |
| REPH | New | RECRO PHARMA INC | $177,000 | – | 25,231 | – | 0.16% | – |
| PGNX | New | PROGENICS PHARMACEUTICALS IN | $148,000 | – | 21,782 | – | 0.14% | – |
| SCYX | New | SCYNEXIS INC | $119,000 | – | 66,608 | – | 0.11% | – |
Q4 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NVAX | Exit | NOVAVAX INC | $0 | – | -25,787 | – | -0.03% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -14,000 | – | -0.10% | – |
| GRFS | Exit | GRIFOLS S Asp adr rep b nvt | $0 | – | -11,849 | – | -0.11% | – |
| LBIO | Exit | LION BIOTECHNOLOGIES INC | $0 | – | -23,594 | – | -0.11% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -4,068 | – | -0.12% | – |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -14,844 | – | -0.12% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -1,768 | – | -0.12% | – |
| JUNO | Exit | JUNO THERAPEUTICS INC | $0 | – | -6,918 | – | -0.12% | – |
| ICPT | Exit | INTERCEPT PHARMACEUTICALS IN | $0 | – | -1,306 | – | -0.12% | – |
| Q | Exit | QUINTILES TRANSNATIO HLDGS I | $0 | – | -2,730 | – | -0.12% | – |
| OPHT | Exit | OPHTHOTECH CORP | $0 | – | -6,746 | – | -0.17% | – |
| CPHD | Exit | CEPHEID | $0 | – | -5,985 | – | -0.18% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -7,074 | – | -0.28% | – |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INC | $0 | – | -25,000 | – | -0.32% | – |
| SDS | Exit | PROSHARES TR | $0 | – | -40,000 | – | -0.37% | – |
| LABU | Exit | DIREXION SHS ETF TRsp biotch bl new | $0 | – | -14,640 | – | -0.40% | – |
| CFRX | Exit | CONTRAFECT CORP | $0 | – | -300,000 | – | -0.42% | – |
| SNR | Exit | NEW SR INVT GROUP INC | $0 | – | -83,700 | – | -0.54% | – |
| ADMS | Exit | ADAMAS PHARMACEUTICALS INC | $0 | – | -60,000 | – | -0.55% | – |
| PRTK | Exit | PARATEK PHARMACEUTICALS INC | $0 | – | -80,000 | – | -0.58% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -28,000 | – | -0.59% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -50,000 | – | -0.96% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB COcall | $0 | – | -45,000 | – | -1.36% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -60,000 | – | -1.45% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -76,439 | – | -1.57% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -32,141 | – | -1.57% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -26,859 | – | -1.58% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -30,639 | – | -1.59% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -54,692 | – | -1.62% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -24,571 | – | -1.69% | – |
| MTD | Exit | METTLER TOLEDO INTERNATIONAL | $0 | – | -7,188 | – | -1.69% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -7,512 | – | -1.69% | – |
| QGEN | Exit | QIAGEN NV | $0 | – | -110,565 | – | -1.70% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -176,611 | – | -1.70% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -45,064 | – | -1.71% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -18,322 | – | -1.71% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -34,626 | – | -1.83% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -18,400 | – | -1.88% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -10,704 | – | -1.88% | – |
| SGEN | Exit | SEATTLE GENETICS INC | $0 | – | -67,953 | – | -2.06% | – |
| PFE | Exit | PFIZER INC | $0 | – | -112,300 | – | -2.13% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -81,677 | – | -2.15% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -120,000 | – | -2.21% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB CO | $0 | – | -75,686 | – | -2.29% | – |
| BIB | Exit | PROSHARES TR | $0 | – | -85,000 | – | -2.31% | – |
| MRK | Exit | MERCK & CO INC | $0 | – | -83,700 | – | -2.93% | – |
| IBB | Exit | ISHARES TRnasdq biotec etf | $0 | – | -25,000 | – | -4.06% | – |
| XBI | Exit | SPDR SERIES TRUSTs&p biotech | $0 | – | -130,000 | – | -4.83% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -430,400 | – | -16.00% | – |
| IWM | Exit | ISHARES TRput | $0 | – | -350,000 | – | -24.38% | – |
Q3 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IWM | New | ISHARES TRput | $43,474,000 | – | 350,000 | – | 24.38% | – |
| XBI | New | SPDR SERIES TRUSTput | $28,531,000 | – | 430,400 | – | 16.00% | – |
| XBI | Buy | SPDR SERIES TRUSTs&p biotech | $8,618,000 | +170.8% | 130,000 | +120.9% | 4.83% | +57.2% |
| IBB | Buy | ISHARES TRnasdq biotec etf | $7,236,000 | +59.0% | 25,000 | +41.4% | 4.06% | -7.6% |
| BIB | New | PROSHARES TR | $4,119,000 | – | 85,000 | – | 2.31% | – |
| BMY | Buy | BRISTOL MYERS SQUIBB CO | $4,081,000 | -22.6% | 75,686 | +5.6% | 2.29% | -55.1% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $3,943,000 | +20.3% | 120,000 | +10.5% | 2.21% | -30.2% |
| ALKS | Sell | ALKERMES PLC | $3,841,000 | +7.3% | 81,677 | -1.4% | 2.15% | -37.7% |
| SGEN | Sell | SEATTLE GENETICS INC | $3,670,000 | +22.6% | 67,953 | -8.3% | 2.06% | -28.8% |
| BIIB | Buy | BIOGEN INC | $3,351,000 | +53.2% | 10,704 | +18.4% | 1.88% | -11.0% |
| ILMN | Sell | ILLUMINA INC | $3,343,000 | +27.1% | 18,400 | -1.8% | 1.88% | -26.2% |
| INCY | Sell | INCYTE CORP | $3,265,000 | +15.9% | 34,626 | -1.7% | 1.83% | -32.7% |
| AMGN | Sell | AMGEN INC | $3,056,000 | +7.9% | 18,322 | -1.6% | 1.71% | -37.4% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $3,054,000 | +26.0% | 45,064 | +3.2% | 1.71% | -26.8% |
| QGEN | Buy | QIAGEN NV | $3,034,000 | +31.6% | 110,565 | +4.6% | 1.70% | -23.6% |
| NKTR | Sell | NEKTAR THERAPEUTICS | $3,034,000 | +19.4% | 176,611 | -1.1% | 1.70% | -30.7% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $3,020,000 | +19.6% | 7,512 | +3.9% | 1.69% | -30.6% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $3,011,000 | +49.1% | 24,571 | +42.0% | 1.69% | -13.4% |
| AGIO | Buy | AGIOS PHARMACEUTICALS INC | $2,889,000 | +59.3% | 54,692 | +26.3% | 1.62% | -7.5% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $2,835,000 | +26.0% | 30,639 | +6.0% | 1.59% | -26.8% |
| CELG | Buy | CELGENE CORP | $2,808,000 | +24.1% | 26,859 | +17.1% | 1.58% | -27.9% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $2,803,000 | +7.7% | 32,141 | +6.3% | 1.57% | -37.4% |
| IONS | Buy | IONIS PHARMACEUTICALS INC | $2,801,000 | +69.7% | 76,439 | +7.9% | 1.57% | -1.5% |
| GSK | Buy | GLAXOSMITHKLINE PLCsponsored adr | $2,588,000 | +19.4% | 60,000 | +20.0% | 1.45% | -30.7% |
| BMY | New | BRISTOL MYERS SQUIBB COcall | $2,426,000 | – | 45,000 | – | 1.36% | – |
| PCRX | New | PACIRA PHARMACEUTICALS INC | $1,711,000 | – | 50,000 | – | 0.96% | – |
| MDCO | Buy | MEDICINES CO | $1,057,000 | +126.3% | 28,000 | +101.7% | 0.59% | +31.5% |
| PRTK | Buy | PARATEK PHARMACEUTICALS INC | $1,041,000 | +98.7% | 80,000 | +112.4% | 0.58% | +15.4% |
| ADMS | Buy | ADAMAS PHARMACEUTICALS INC | $985,000 | +44.0% | 60,000 | +32.7% | 0.55% | -16.5% |
| CFRX | New | CONTRAFECT CORP | $744,000 | – | 300,000 | – | 0.42% | – |
| PTLA | New | PORTOLA PHARMACEUTICALS INC | $568,000 | – | 25,000 | – | 0.32% | – |
| CPHD | Sell | CEPHEID | $315,000 | +50.7% | 5,985 | -11.8% | 0.18% | -12.4% |
| Q | Sell | QUINTILES TRANSNATIO HLDGS I | $221,000 | -84.3% | 2,730 | -87.3% | 0.12% | -90.9% |
| ICPT | New | INTERCEPT PHARMACEUTICALS IN | $215,000 | – | 1,306 | – | 0.12% | – |
| JUNO | New | JUNO THERAPEUTICS INC | $208,000 | – | 6,918 | – | 0.12% | – |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $209,000 | -4.6% | 1,768 | -14.3% | 0.12% | -44.8% |
| AXGT | Buy | AXOVANT SCIENCES LTD | $208,000 | +20.9% | 14,844 | +10.9% | 0.12% | -29.5% |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $206,000 | – | 4,068 | – | 0.12% | – |
| LBIO | Sell | LION BIOTECHNOLOGIES INC | $194,000 | -1.0% | 23,594 | -2.6% | 0.11% | -42.3% |
| GRFS | Buy | GRIFOLS S Asp adr rep b nvt | $189,000 | +1.1% | 11,849 | +5.9% | 0.11% | -41.4% |
| MCRB | Sell | SERES THERAPEUTICS INC | $172,000 | -70.9% | 14,000 | -31.2% | 0.10% | -83.2% |
| NVAX | Sell | NOVAVAX INC | $54,000 | -74.5% | 25,787 | -11.4% | 0.03% | -85.4% |
| HOLX | Exit | HOLOGIC INC | $0 | – | -16,500 | – | -0.55% | – |
| MDVN | Exit | MEDIVATION INC | $0 | – | -51,561 | – | -3.00% | – |
| IWM | Exit | ISHARES TRrussell 2000 etf | $0 | – | -200,000 | – | -22.21% | – |
Q2 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IWM | New | ISHARES TRrussell 2000 etf | $22,996,000 | – | 200,000 | – | 22.21% | – |
| BMY | New | BRISTOL MYERS SQUIBB CO | $5,274,000 | – | 71,703 | – | 5.09% | – |
| MRK | New | MERCK & CO INC | $4,822,000 | – | 83,700 | – | 4.66% | – |
| IBB | New | ISHARES TRnasdq biotec etf | $4,550,000 | – | 17,681 | – | 4.39% | – |
| PFE | New | PFIZER INC | $3,954,000 | – | 112,300 | – | 3.82% | – |
| ALKS | New | ALKERMES PLC | $3,581,000 | – | 82,858 | – | 3.46% | – |
| AZN | New | ASTRAZENECA PLCsponsored adr | $3,278,000 | – | 108,563 | – | 3.17% | – |
| XBI | New | SPDR SERIES TRUSTs&p biotech | $3,183,000 | – | 58,857 | – | 3.07% | – |
| MDVN | New | MEDIVATION INC | $3,109,000 | – | 51,561 | – | 3.00% | – |
| SGEN | New | SEATTLE GENETICS INC | $2,994,000 | – | 74,093 | – | 2.89% | – |
| AMGN | New | AMGEN INC | $2,833,000 | – | 18,619 | – | 2.74% | – |
| INCY | New | INCYTE CORP | $2,818,000 | – | 35,237 | – | 2.72% | – |
| ILMN | New | ILLUMINA INC | $2,631,000 | – | 18,741 | – | 2.54% | – |
| MTD | New | METTLER TOLEDO INTERNATIONAL | $2,623,000 | – | 7,188 | – | 2.53% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $2,602,000 | – | 30,248 | – | 2.51% | – |
| NKTR | New | NEKTAR THERAPEUTICS | $2,540,000 | – | 178,531 | – | 2.45% | – |
| REGN | New | REGENERON PHARMACEUTICALS | $2,526,000 | – | 7,233 | – | 2.44% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $2,424,000 | – | 43,684 | – | 2.34% | – |
| QGEN | New | QIAGEN NV | $2,306,000 | – | 105,751 | – | 2.23% | – |
| CELG | New | CELGENE CORP | $2,262,000 | – | 22,932 | – | 2.18% | – |
| BMRN | New | BIOMARIN PHARMACEUTICAL INC | $2,250,000 | – | 28,915 | – | 2.17% | – |
| BIIB | New | BIOGEN INC | $2,187,000 | – | 9,042 | – | 2.11% | – |
| GSK | New | GLAXOSMITHKLINE PLCsponsored adr | $2,167,000 | – | 50,000 | – | 2.09% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $2,020,000 | – | 17,301 | – | 1.95% | – |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $1,814,000 | – | 43,295 | – | 1.75% | – |
| IONS | New | IONIS PHARMACEUTICALS INC | $1,651,000 | – | 70,868 | – | 1.60% | – |
| Q | New | QUINTILES TRANSNATIO HLDGS I | $1,406,000 | – | 21,520 | – | 1.36% | – |
| SNR | New | NEW SR INVT GROUP INC | $894,000 | – | 83,700 | – | 0.86% | – |
| SDS | New | PROSHARES TR | $712,000 | – | 40,000 | – | 0.69% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $684,000 | – | 45,198 | – | 0.66% | – |
| MCRB | New | SERES THERAPEUTICS INC | $591,000 | – | 20,339 | – | 0.57% | – |
| HOLX | New | HOLOGIC INC | $571,000 | – | 16,500 | – | 0.55% | – |
| PRTK | New | PARATEK PHARMACEUTICALS INC | $524,000 | – | 37,665 | – | 0.51% | – |
| MDCO | New | MEDICINES CO | $467,000 | – | 13,885 | – | 0.45% | – |
| LABU | New | DIREXION SHS ETF TRsp biotch bl new | $413,000 | – | 14,640 | – | 0.40% | – |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $346,000 | – | 7,074 | – | 0.33% | – |
| OPHT | New | OPHTHOTECH CORP | $344,000 | – | 6,746 | – | 0.33% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $219,000 | – | 2,064 | – | 0.21% | – |
| NVAX | New | NOVAVAX INC | $212,000 | – | 29,107 | – | 0.20% | – |
| CPHD | New | CEPHEID | $209,000 | – | 6,782 | – | 0.20% | – |
| LBIO | New | LION BIOTECHNOLOGIES INC | $196,000 | – | 24,226 | – | 0.19% | – |
| GRFS | New | GRIFOLS S Asp adr rep b nvt | $187,000 | – | 11,188 | – | 0.18% | – |
| AXGT | New | AXOVANT SCIENCES LTD | $172,000 | – | 13,389 | – | 0.17% | – |
Q4 2015
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FLDM | Exit | FLUIDIGM CORP DEL | $0 | – | -15,000 | – | -0.07% | – |
| XNPT | Exit | XENOPORT INC | $0 | – | -40,000 | – | -0.08% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -15,000 | – | -0.08% | – |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -14,750 | – | -0.09% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -57,747 | – | -0.10% | – |
| LABU | Exit | DIREXION SHS ETF TR | $0 | – | -14,850 | – | -0.13% | – |
| NHLD | Exit | NATIONAL HOLDINGS CORP | $0 | – | -89,530 | – | -0.14% | – |
| OPHT | Exit | OPHTHOTECH CORP | $0 | – | -7,150 | – | -0.16% | – |
| ARWR | Exit | ARROWHEAD RESH CORP | $0 | – | -51,133 | – | -0.16% | – |
| INFI | Exit | INFINITY PHARMACEUTICALS INC | $0 | – | -45,300 | – | -0.21% | – |
| AXGT | Exit | AXOVANT SCIENCES LTD | $0 | – | -30,722 | – | -0.22% | – |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -4,323 | – | -0.23% | – |
| RPRX | Exit | REPROS THERAPEUTICS INCcall | $0 | – | -98,000 | – | -0.27% | – |
| MACK | Exit | MERRIMACK PHARMACEUTICALS IN | $0 | – | -62,009 | – | -0.29% | – |
| CMRX | Exit | CHIMERIX INC | $0 | – | -14,152 | – | -0.30% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -46,079 | – | -0.33% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -75,000 | – | -0.37% | – |
| NVAX | Exit | NOVAVAX INCcall | $0 | – | -100,000 | – | -0.39% | – |
| NVAX | Exit | NOVAVAX INCput | $0 | – | -100,000 | – | -0.39% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -5,571 | – | -0.40% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS IN | $0 | – | -106,104 | – | -0.40% | – |
| CRIS | Exit | CURIS INC | $0 | – | -374,500 | – | -0.42% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -5,626 | – | -0.43% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INC | $0 | – | -21,000 | – | -0.48% | – |
| ZGNX | Exit | ZOGENIX INC | $0 | – | -65,700 | – | -0.49% | – |
| VCEL | Exit | VERICEL CORP | $0 | – | -332,157 | – | -0.50% | – |
| FLML | Exit | FLAMEL TECHNOLOGIES SAsponsored adr | $0 | – | -56,788 | – | -0.51% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -250,000 | – | -0.63% | – |
| NSTG | Exit | NANOSTRING TECHNOLOGIES INC | $0 | – | -102,200 | – | -0.90% | – |
| HOLX | Exit | HOLOGIC INC | $0 | – | -48,000 | – | -1.04% | – |
| BIB | Exit | PROSHARES TR | $0 | – | -32,717 | – | -1.05% | – |
| MRK | Exit | MERCK & CO INC NEW | $0 | – | -41,000 | – | -1.12% | – |
| BMY | Exit | BRISTOL MYERS SQUIBB CO | $0 | – | -36,000 | – | -1.18% | – |
| AGIO | Exit | AGIOS PHARMACEUTICALS INC | $0 | – | -46,000 | – | -1.79% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -48,448 | – | -2.15% | – |
| CPHD | Exit | CEPHEID | $0 | – | -90,000 | – | -2.25% | – |
| ISIS | Exit | ISIS PHARMACEUTICALS INC | $0 | – | -101,401 | – | -2.26% | – |
| QGEN | Exit | QIAGEN NV | $0 | – | -160,000 | – | -2.28% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -40,876 | – | -2.35% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -136,000 | – | -2.39% | – |
| MTD | Exit | METTLER TOLEDO INTERNATIONAL | $0 | – | -15,200 | – | -2.39% | – |
| TECH | Exit | BIO TECHNE CORP | $0 | – | -47,000 | – | -2.40% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -42,012 | – | -2.44% | – |
| SGEN | Exit | SEATTLE GENETICS INC | $0 | – | -124,558 | – | -2.65% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -444,258 | – | -2.69% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -10,627 | – | -2.73% | – |
| ILMN | Exit | ILLUMINA INC | $0 | – | -28,334 | – | -2.75% | – |
| MDVN | Exit | MEDIVATION INC | $0 | – | -118,372 | – | -2.78% | – |
| ALKS | Exit | ALKERMES PLC | $0 | – | -86,864 | – | -2.81% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -17,467 | – | -2.81% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -47,137 | – | -2.82% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -33,021 | – | -2.85% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -47,400 | – | -2.89% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -58,567 | – | -2.97% | – |
| IBB | Exit | ISHARES TRnasdq biotec etf | $0 | – | -20,000 | – | -3.35% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -862,500 | – | -29.65% | – |
Q3 2015
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | Buy | SPDR SERIES TRUSTput | $53,691,000 | +3877.1% | 862,500 | +86150.0% | 29.65% | +2673.2% |
| IBB | New | ISHARES TRnasdq biotec etf | $6,067,000 | – | 20,000 | – | 3.35% | – |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $5,386,000 | +17.0% | 58,567 | +11.8% | 2.97% | -18.5% |
| INCY | Buy | INCYTE CORP | $5,230,000 | +19.8% | 47,400 | +13.2% | 2.89% | -16.4% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $5,164,000 | +33.0% | 33,021 | +53.8% | 2.85% | -7.3% |
| CELG | Buy | CELGENE CORP | $5,099,000 | +14.8% | 47,137 | +22.8% | 2.82% | -20.0% |
| ALKS | Buy | ALKERMES PLC | $5,096,000 | +11.5% | 86,864 | +22.3% | 2.81% | -22.2% |
| BIIB | Buy | BIOGEN INC | $5,097,000 | +12.1% | 17,467 | +55.2% | 2.81% | -21.8% |
| MDVN | Buy | MEDIVATION INC | $5,031,000 | +28.3% | 118,372 | +244.7% | 2.78% | -10.6% |
| ILMN | Buy | ILLUMINA INC | $4,982,000 | +6.4% | 28,334 | +32.1% | 2.75% | -25.8% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $4,943,000 | +10.6% | 10,627 | +21.3% | 2.73% | -22.9% |
| NKTR | Buy | NEKTAR THERAPEUTICS | $4,869,000 | +5.8% | 444,258 | +20.7% | 2.69% | -26.3% |
| SGEN | Buy | SEATTLE GENETICS INC | $4,803,000 | -4.9% | 124,558 | +19.4% | 2.65% | -33.7% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $4,425,000 | -9.9% | 42,012 | +17.0% | 2.44% | -37.2% |
| TECH | Buy | BIO TECHNE CORP | $4,346,000 | +29.8% | 47,000 | +38.2% | 2.40% | -9.5% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $4,328,000 | +35.8% | 136,000 | +172.0% | 2.39% | -5.3% |
| MTD | Buy | METTLER TOLEDO INTERNATIONAL | $4,328,000 | +15.2% | 15,200 | +38.2% | 2.39% | -19.7% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $4,257,000 | -2.3% | 40,876 | +15.9% | 2.35% | -31.9% |
| QGEN | Buy | QIAGEN NV | $4,128,000 | +18.9% | 160,000 | +14.3% | 2.28% | -17.1% |
| ISIS | Buy | ISIS PHARMACEUTICALS INC | $4,099,000 | +7.6% | 101,401 | +53.2% | 2.26% | -25.0% |
| CPHD | Buy | CEPHEID | $4,068,000 | +4.5% | 90,000 | +41.4% | 2.25% | -27.1% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $3,893,000 | -7.2% | 48,448 | +38.5% | 2.15% | -35.3% |
| AGIO | New | AGIOS PHARMACEUTICALS INC | $3,247,000 | – | 46,000 | – | 1.79% | – |
| BMY | New | BRISTOL MYERS SQUIBB CO | $2,131,000 | – | 36,000 | – | 1.18% | – |
| MRK | New | MERCK & CO INC NEW | $2,025,000 | – | 41,000 | – | 1.12% | – |
| BIB | Sell | PROSHARES TR | $1,906,000 | -60.6% | 32,717 | -38.9% | 1.05% | -72.6% |
| NSTG | Buy | NANOSTRING TECHNOLOGIES INC | $1,635,000 | +76.8% | 102,200 | +70.3% | 0.90% | +23.2% |
| ARRY | Sell | ARRAY BIOPHARMA INC | $1,140,000 | -50.6% | 250,000 | -21.9% | 0.63% | -65.6% |
| FLML | Buy | FLAMEL TECHNOLOGIES SAsponsored adr | $926,000 | -15.6% | 56,788 | +9.7% | 0.51% | -41.2% |
| VCEL | Sell | VERICEL CORP | $900,000 | -30.4% | 332,157 | -8.3% | 0.50% | -51.5% |
| ZGNX | New | ZOGENIX INC | $887,000 | – | 65,700 | – | 0.49% | – |
| PCRX | Sell | PACIRA PHARMACEUTICALS INC | $863,000 | -74.0% | 21,000 | -55.3% | 0.48% | -81.9% |
| AMGN | Buy | AMGEN INC | $778,000 | -8.7% | 5,626 | +1.4% | 0.43% | -36.3% |
| CRIS | Buy | CURIS INC | $756,000 | +6.2% | 374,500 | +74.2% | 0.42% | -26.1% |
| ACHN | Buy | ACHILLION PHARMACEUTICALS IN | $733,000 | +24.0% | 106,104 | +59.1% | 0.40% | -13.5% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $731,000 | -22.2% | 5,571 | +3.2% | 0.40% | -45.7% |
| NVAX | New | NOVAVAX INCcall | $707,000 | – | 100,000 | – | 0.39% | – |
| NVAX | New | NOVAVAX INCput | $707,000 | – | 100,000 | – | 0.39% | – |
| EPZM | Sell | EPIZYME INC | $593,000 | -65.9% | 46,079 | -36.3% | 0.33% | -76.2% |
| CMRX | Sell | CHIMERIX INC | $541,000 | -38.9% | 14,152 | -26.1% | 0.30% | -57.3% |
| MACK | Sell | MERRIMACK PHARMACEUTICALS IN | $528,000 | -40.7% | 62,009 | -13.9% | 0.29% | -58.6% |
| RPRX | New | REPROS THERAPEUTICS INCcall | $494,000 | – | 98,000 | – | 0.27% | – |
| GILD | Buy | GILEAD SCIENCES INC | $424,000 | -14.5% | 4,323 | +2.1% | 0.23% | -40.5% |
| AXGT | New | AXOVANT SCIENCES LTD | $397,000 | – | 30,722 | – | 0.22% | – |
| INFI | Sell | INFINITY PHARMACEUTICALS INC | $383,000 | -56.3% | 45,300 | -43.4% | 0.21% | -69.6% |
| ARWR | Sell | ARROWHEAD RESH CORP | $295,000 | -49.7% | 51,133 | -37.7% | 0.16% | -64.9% |
| OPHT | New | OPHTHOTECH CORP | $290,000 | – | 7,150 | – | 0.16% | – |
| LABU | New | DIREXION SHS ETF TR | $241,000 | – | 14,850 | – | 0.13% | – |
| ACRX | Sell | ACELRX PHARMACEUTICALS INC | $176,000 | -58.5% | 57,747 | -42.2% | 0.10% | -71.1% |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $155,000 | – | 14,750 | – | 0.09% | – |
| ASMB | Sell | ASSEMBLY BIOSCIENCES INC | $143,000 | -88.6% | 15,000 | -76.9% | 0.08% | -92.0% |
| XNPT | Sell | XENOPORT INC | $139,000 | -82.6% | 40,000 | -69.2% | 0.08% | -87.8% |
| FLDM | New | FLUIDIGM CORP DEL | $122,000 | – | 15,000 | – | 0.07% | – |
| NEPT | Exit | NEPTUNE TECH & BIORES INC. CMN | $0 | – | -15 | – | -0.00% | – |
| JUNO | Exit | JUNO THERAPEUTICS, INC. CMNput | $0 | – | -50 | – | -0.04% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC CMNcall | $0 | – | -2,000 | – | -0.11% | – |
| JUNO | Exit | JUNO THERAPEUTICS, INC. CMN | $0 | – | -5,000 | – | -0.21% | – |
| KBIO | Exit | KALOBIOS PHARMACEUTICALS INC CMN | $0 | – | -746,467 | – | -0.28% | – |
| RPRXZ | Exit | WTS/REPROS THERAPEUTICS INC. SERIES B 2.4500 EXP02/07/2016call | $0 | – | -98,000 | – | -0.36% | – |
| ZGNX | Exit | ZOGENIX, INC. CMN | $0 | – | -300,000 | – | -0.40% | – |
| RLYP | Exit | RELYPSA, INC. CMN | $0 | – | -18,000 | – | -0.47% | – |
| BIOD | Exit | BIODEL INC CMN | $0 | – | -650,000 | – | -0.53% | – |
| OCRX | Exit | OCERA THERAPEUTICS INC CMN CLASS | $0 | – | -186,573 | – | -0.56% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL INC. CMN | $0 | – | -9,000 | – | -0.73% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC CMN | $0 | – | -15,000 | – | -0.97% | – |
| TSRO | Exit | TESARO INC CMN | $0 | – | -30,000 | – | -1.40% | – |
| RCPT | Exit | RECEPTOS, INC. CMN | $0 | – | -28,124 | – | -4.23% | – |