Rock Springs Capital Management LP

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$2.12 Billion is the total value of Rock Springs Capital Management LP's 133 reported holdings in Q4 2018. The portfolio turnover from Q3 2018 to Q4 2018 was 16.0% .

All

			Value		Shares		↓ Weighting
UNH	Buy	UNITEDHEALTH GROUP INC	$150,244,000	-4.1%	603,100	+2.4%	7.09%	+25.0%
WCG	Buy	WELLCARE HEALTH PLANS INC	$91,957,000	+21.8%	389,500	+65.4%	4.34%	+58.8%
ISRG	Buy	INTUITIVE SURGICAL INC	$72,796,000	-10.3%	152,000	+7.5%	3.44%	+16.9%
AMRN	Buy	AMARIN CORP PLCspons adr new	$60,918,000	-13.4%	4,476,000	+3.5%	2.88%	+12.8%
GWPH	Buy	GW PHARMACEUTICALS PLCads	$58,385,000	-15.5%	599,500	+49.9%	2.76%	+10.2%
HCA		HCA HEALTHCARE INC	$56,625,000	-10.5%	455,000	0.0%	2.67%	+16.6%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$56,314,000	-29.0%	788,600	+22.3%	2.66%	-7.4%
PCRX	Sell	PACIRA PHARMACEUTICALS INC	$53,775,000	-15.3%	1,250,000	-3.3%	2.54%	+10.3%
EHC	Buy	ENCOMPASS HEALTH CORP	$44,733,000	-15.2%	725,000	+7.2%	2.11%	+10.6%
TSRO	Sell	TESARO INC	$44,676,000	+55.8%	601,700	-18.1%	2.11%	+103.2%
MOH	Sell	MOLINA HEALTHCARE INC	$39,747,000	-51.0%	342,000	-37.2%	1.88%	-36.1%
SRPT	Buy	SAREPTA THERAPEUTICS INC	$35,686,000	-28.8%	327,000	+5.3%	1.68%	-7.3%
LOXO	Buy	LOXO ONCOLOGY INC	$33,827,000	-2.4%	241,500	+19.0%	1.60%	+27.3%
VRTX	Buy	VERTEX PHARMACEUTICALS INC	$33,639,000	-11.0%	203,000	+3.6%	1.59%	+16.1%
TFX	Buy	TELEFLEX INC	$33,602,000	+1.8%	130,000	+4.8%	1.59%	+32.7%
IRTC	Buy	IRHYTHM TECHNOLOGIES INC	$33,489,000	-26.3%	482,000	+0.4%	1.58%	-3.9%
BSX	Buy	BOSTON SCIENTIFIC CORP	$32,336,000	+5.0%	915,000	+14.4%	1.53%	+36.9%
BGNE	Sell	BEIGENE LTDsponsored adr	$30,128,000	-18.6%	214,800	-0.1%	1.42%	+6.0%
EW	Buy	EDWARDS LIFESCIENCES CORP	$28,107,000	-10.3%	183,500	+1.9%	1.33%	+16.9%
SYK		STRYKER CORP	$28,058,000	-11.8%	179,000	0.0%	1.32%	+14.9%
COLL	Sell	COLLEGIUM PHARMACEUTICAL INC	$27,560,000	+13.3%	1,605,105	-2.7%	1.30%	+47.7%
PEN	Sell	PENUMBRA INC	$27,495,000	-21.9%	225,000	-4.3%	1.30%	+1.8%
WMGI		WRIGHT MED GROUP N V	$27,220,000	-6.2%	1,000,000	0.0%	1.28%	+22.3%
MDGL	Sell	MADRIGAL PHARMACEUTICALS INC	$27,166,000	-62.9%	241,000	-29.5%	1.28%	-51.6%
EXAS		EXACT SCIENCES CORP	$24,294,000	-20.0%	385,000	0.0%	1.15%	+4.3%
ALXN	Sell	ALEXION PHARMACEUTICALS INC	$23,610,000	-43.4%	242,500	-19.2%	1.11%	-26.2%
ACHC	Buy	ACADIA HEALTHCARE COMPANY IN	$23,158,000	-6.0%	900,750	+28.7%	1.09%	+22.5%
ALGN	Buy	ALIGN TECHNOLOGY INC	$21,990,000	-16.7%	105,000	+55.6%	1.04%	+8.6%
TMO		THERMO FISHER SCIENTIFIC INC	$21,484,000	-8.3%	96,000	0.0%	1.01%	+19.6%
ALLK	Sell	ALLAKOS INC	$21,117,000	+15.9%	404,000	-0.2%	1.00%	+51.1%
ONCE		SPARK THERAPEUTICS INC	$21,038,000	-28.2%	537,500	0.0%	0.99%	-6.5%
IDXX	Buy	IDEXX LABS INC	$20,555,000	-1.4%	110,500	+32.3%	0.97%	+28.5%
BAX	Buy	BAXTER INTL INC	$19,792,000	-13.6%	300,700	+1.2%	0.93%	+12.7%
INCY	Sell	INCYTE CORP	$19,713,000	-19.0%	310,000	-12.0%	0.93%	+5.6%
RARE	Buy	ULTRAGENYX PHARMACEUTICAL IN	$18,479,000	+21.0%	425,000	+112.5%	0.87%	+57.7%
PRAH	Sell	PRA HEALTH SCIENCES INC	$18,392,000	-42.1%	200,000	-30.6%	0.87%	-24.5%
RDUS	Sell	RADIUS HEALTH INC	$18,139,000	-19.6%	1,100,000	-13.2%	0.86%	+4.8%
ARGX	Buy	ARGENX SEsponsored adr	$17,100,000	+36.6%	178,000	+7.9%	0.81%	+78.1%
GLPG		GALAPAGOS NVspon adr	$16,284,000	-18.4%	177,500	0.0%	0.77%	+6.4%
WST		WEST PHARMACEUTICAL SVSC INC	$15,685,000	-20.6%	160,000	0.0%	0.74%	+3.5%
NVTA		INVITAE CORP	$15,484,000	-33.9%	1,400,000	0.0%	0.73%	-13.8%
ASND		ASCENDIS PHARMA A Ssponsored adr	$15,255,000	-11.6%	243,500	0.0%	0.72%	+15.2%
ALDR	Sell	ALDER BIOPHARMACEUTICALS INC	$15,119,000	-44.4%	1,475,000	-9.6%	0.71%	-27.4%
BIIB		BIOGEN INC	$15,046,000	-14.8%	50,000	0.0%	0.71%	+10.9%
INGN	Sell	INOGEN INC	$14,528,000	-52.8%	117,000	-7.1%	0.69%	-38.4%
OBSV		OBSEVA SA	$14,179,000	-29.8%	1,120,000	0.0%	0.67%	-8.5%
ALNY	Sell	ALNYLAM PHARMACEUTICALS INC	$14,145,000	-17.8%	194,000	-1.3%	0.67%	+7.2%
FGEN		FIBROGEN INC	$14,162,000	-23.8%	306,000	0.0%	0.67%	-0.7%
TBPH		THERAVANCE BIOPHARMA INC	$14,075,000	-21.7%	550,000	0.0%	0.66%	+2.0%
MDCO	Buy	MEDICINES CO	$13,913,000	-32.6%	726,900	+5.3%	0.66%	-12.0%
RARX		RA PHARMACEUTICALS INC	$13,650,000	+0.6%	750,000	0.0%	0.64%	+31.2%
HRTX		HERON THERAPEUTICS INC	$13,619,000	-18.0%	525,000	0.0%	0.64%	+6.8%
XENT	Buy	INTERSECT ENT INC	$13,104,000	-0.9%	465,000	+1.1%	0.62%	+29.2%
AXGN	Buy	AXOGEN INC	$12,339,000	-38.4%	603,970	+11.1%	0.58%	-19.7%
A	Buy	AGILENT TECHNOLOGIES INC	$12,332,000	+6.5%	182,800	+11.4%	0.58%	+38.9%
EXEL	Buy	EXELIXIS INC	$12,223,000	+15.9%	621,400	+4.4%	0.58%	+51.0%
ZBH	Sell	ZIMMER BIOMET HLDGS INC	$12,187,000	-58.8%	117,500	-47.8%	0.58%	-46.3%
CELG	Sell	CELGENE CORP	$11,866,000	-63.2%	185,150	-48.6%	0.56%	-52.1%
BPMC	Buy	BLUEPRINT MEDICINES CORP	$11,518,000	-26.2%	213,658	+6.8%	0.54%	-3.7%
SGEN	New	SEATTLE GENETICS INC	$11,474,000	–	202,500	+100.0%	0.54%	–
INSM	Sell	INSMED INC	$11,152,000	-38.0%	850,000	-4.5%	0.53%	-19.3%
IMMU	Buy	IMMUNOMEDICS INC	$11,131,000	-31.0%	780,000	+0.6%	0.52%	-10.1%
DVA	Sell	DAVITA INC	$11,074,000	-62.2%	215,200	-47.3%	0.52%	-50.6%
BMRN	Buy	BIOMARIN PHARMACEUTICAL INC	$10,984,000	-9.4%	129,000	+3.2%	0.52%	+18.0%
BOLD	Buy	AUDENTES THERAPEUTICS INC	$10,660,000	-36.6%	500,000	+17.6%	0.50%	-17.4%
ASMB	Sell	ASSEMBLY BIOSCIENCES INC	$10,179,000	-44.1%	450,000	-8.2%	0.48%	-27.2%
FIXX	Sell	HOMOLOGY MEDICINES INC	$10,062,000	-6.3%	450,000	-4.3%	0.48%	+22.1%
GBT	Buy	GLOBAL BLOOD THERAPEUTICS IN	$10,057,000	+76.4%	245,000	+63.3%	0.48%	+130.6%
EPZM	Buy	EPIZYME INC	$9,902,000	-24.7%	1,607,500	+29.5%	0.47%	-1.9%
ACRS	Buy	ACLARIS THERAPEUTICS INC	$9,824,000	-23.1%	1,329,400	+51.1%	0.46%	+0.2%
RIGL	Buy	RIGEL PHARMACEUTICALS INC	$9,660,000	-27.0%	4,200,000	+1.8%	0.46%	-4.8%
BHVN		BIOHAVEN PHARMACTL HLDG CO L	$9,615,000	-1.5%	260,000	0.0%	0.45%	+28.6%
FOLD		AMICUS THERAPEUTICS INC	$9,580,000	-20.8%	1,000,000	0.0%	0.45%	+3.2%
PBYI	Sell	PUMA BIOTECHNOLOGY INC	$9,289,000	-58.4%	456,462	-6.4%	0.44%	-45.9%
RTRX		RETROPHIN INC	$9,052,000	-21.2%	400,000	0.0%	0.43%	+2.6%
ANAB	Sell	ANAPTYSBIO INC	$8,675,000	-47.3%	136,000	-17.6%	0.41%	-31.4%
ZGNX		ZOGENIX INC	$8,568,000	-26.5%	235,000	0.0%	0.40%	-4.3%
ZLAB		ZAI LAB LTDadr	$8,127,000	+19.2%	350,000	0.0%	0.38%	+55.5%
GH	New	GUARDANT HEALTH INC	$8,119,000	–	216,000	+100.0%	0.38%	–
IFRX	Buy	INFLARX NV	$7,925,000	+30.1%	217,900	+22.8%	0.37%	+69.2%
TBIO		TRANSLATE BIO INC	$7,569,000	-25.0%	1,009,179	0.0%	0.36%	-2.2%
FRPT	New	FRESHPET INC	$7,558,000	–	235,000	+100.0%	0.36%	–
RTIX		RTI SURGICAL INC	$7,215,000	-17.8%	1,950,000	0.0%	0.34%	+7.2%
NVCR	Buy	NOVOCURE LTD	$6,529,000	+398.4%	195,000	+680.0%	0.31%	+555.3%
MRTX	Sell	MIRATI THERAPEUTICS INC	$6,363,000	-43.7%	150,000	-37.5%	0.30%	-26.7%
ODT	Buy	ODONATE THERAPEUTICS INC	$6,266,000	-25.9%	445,000	+2.2%	0.30%	-3.3%
CHRS		COHERUS BIOSCIENCES INC	$6,064,000	-45.1%	670,000	0.0%	0.29%	-28.5%
AXNX	New	AXONICS MODULATION TECH INC	$6,044,000	–	400,000	+100.0%	0.28%	–
CO		GLOBAL CORD BLOOD CORPORATIO	$5,966,000	-7.7%	925,000	0.0%	0.28%	+20.5%
NVAX		NOVAVAX INC	$5,980,000	-2.1%	3,250,000	0.0%	0.28%	+27.6%
PTLA	Sell	PORTOLA PHARMACEUTICALS INC	$5,856,000	-32.1%	300,000	-7.4%	0.28%	-11.5%
RYTM	Buy	RHYTHM PHARMACEUTICALS INC	$5,820,000	-7.2%	216,500	+0.7%	0.28%	+21.1%
MYOV		MYOVANT SCIENCES LTD	$5,702,000	-38.2%	347,500	0.0%	0.27%	-19.5%
BCRX		BIOCRYST PHARMACEUTICALS	$5,649,000	+5.8%	700,000	0.0%	0.27%	+38.3%
APTX		APTINYX INC	$5,045,000	-42.9%	305,000	0.0%	0.24%	-25.6%
AGLE		AEGLEA BIOTHERAPEUTICS INC	$4,869,000	-21.7%	650,000	0.0%	0.23%	+2.2%
CBAY		CYMABAY THERAPEUTICS INC	$4,829,000	-29.0%	613,604	0.0%	0.23%	-7.3%
SAGE		SAGE THERAPEUTICS INC	$4,694,000	-32.2%	49,000	0.0%	0.22%	-11.6%
FPRX	Sell	FIVE PRIME THERAPEUTICS INC	$4,697,000	-43.6%	505,000	-15.6%	0.22%	-26.2%
CLVS	Sell	CLOVIS ONCOLOGY INC	$4,598,000	-42.3%	256,000	-5.6%	0.22%	-24.7%
BLUE	Sell	BLUEBIRD BIO INC	$4,464,000	-41.8%	45,000	-14.3%	0.21%	-24.1%
MNTA	Sell	MOMENTA PHARMACEUTICALS INC	$4,416,000	-64.7%	400,000	-15.8%	0.21%	-54.0%
ADAP		ADAPTIMMUNE THERAPEUTICS PLCsponds adr	$4,313,000	-57.6%	750,000	0.0%	0.20%	-44.6%
		INSMED INCnote 1.750% 1/1	$4,296,000	-15.3%	6,000,000	0.0%	0.20%	+10.3%
MRSN		MERSANA THERAPEUTICS INC	$4,080,000	-59.2%	1,000,000	0.0%	0.19%	-46.7%
		ALDER BIOPHARMACEUTICALS INCnote 2.500% 2/0	$4,001,000	-25.4%	5,000,000	0.0%	0.19%	-2.6%
		MEDICINES COnote 2.750% 7/1	$3,793,000	-16.8%	5,000,000	0.0%	0.18%	+8.5%
ACHN	Sell	ACHILLION PHARMACEUTICALS IN	$3,697,000	-58.1%	2,325,000	-3.1%	0.18%	-45.3%
DERM	Sell	DERMIRA INC	$3,717,000	-43.2%	517,000	-13.8%	0.18%	-26.2%
ARDX	Sell	ARDELYX INC	$3,580,000	-67.4%	2,000,000	-20.8%	0.17%	-57.5%
DVAX	Buy	DYNAVAX TECHNOLOGIES CORP	$3,477,000	+4.6%	380,000	+41.8%	0.16%	+36.7%
TORC		RESTORBIO INC	$3,448,000	-43.1%	400,000	0.0%	0.16%	-25.6%
CMTA	Sell	CLEMENTIA PHARMACEUTICALS IN	$3,234,000	-15.9%	275,000	-20.3%	0.15%	+10.1%
SPRO		SPERO THERAPEUTICS INC	$3,229,000	-41.5%	525,000	0.0%	0.15%	-24.0%
CORV		CORREVIO PHARMA CORP	$2,988,000	-38.1%	1,200,000	0.0%	0.14%	-19.4%
LJPC	Sell	LA JOLLA PHARMACEUTICAL CO	$2,614,000	-53.9%	277,236	-1.6%	0.12%	-40.0%
		MEDICINES COnote 2.500% 1/1	$2,589,000	-19.9%	3,000,000	0.0%	0.12%	+4.3%
PHAS	New	PHASEBIO PHARMACEUTICALS INC	$2,580,000	–	835,000	+100.0%	0.12%	–
CGEN	Buy	COMPUGEN LTDord	$2,387,000	-42.5%	1,100,000	+2.0%	0.11%	-24.7%
	Sell	NABRIVA THERAPEUTICS PLC	$2,336,000	-51.9%	1,600,000	-11.1%	0.11%	-37.5%
PRTK		PARATEK PHARMACEUTICALS INC	$2,309,000	-47.1%	450,000	0.0%	0.11%	-31.0%
ARVN		ARVINAS INC	$1,928,000	-23.8%	150,000	0.0%	0.09%	-1.1%
GTHX	Sell	G1 THERAPEUTICS INC	$1,915,000	-84.3%	100,000	-57.1%	0.09%	-79.6%
CHMA		CHIASMA INC	$1,633,000	-13.6%	525,000	0.0%	0.08%	+13.2%
SLDB	Sell	SOLID BIOSCIENCES INC	$1,581,000	-64.7%	58,999	-37.9%	0.08%	-53.7%
		THERAVANCE BIOPHARMA INCnote 3.250%11/0	$1,547,000	-12.6%	1,500,000	0.0%	0.07%	+14.1%
CRVS	Sell	CORVUS PHARMACEUTICALS INC	$1,468,000	-70.2%	400,000	-30.4%	0.07%	-61.5%
PTI	New	PROTEOSTASIS THERAPEUTICS IN	$1,296,000	–	400,000	+100.0%	0.06%	–
		NEUROCRINE BIOSCIENCES INCnote 2.250% 5/1	$1,196,000	-29.9%	1,000,000	0.0%	0.06%	-9.7%
		RADIUS HEALTH INCnote 3.000% 9/0	$1,157,000	+0.3%	1,500,000	0.0%	0.06%	+31.0%
MGNX	Sell	MACROGENICS INC	$1,028,000	-82.6%	80,981	-70.6%	0.05%	-77.0%
		PACIRA PHARMACEUTICALS INCnote 2.375% 4/0	$994,000	-6.2%	1,000,000	0.0%	0.05%	+23.7%
		DERMIRA INCnote 3.000% 5/1	$775,000	-7.1%	1,000,000	0.0%	0.04%	+23.3%
GTXI	Exit	GTX INC DELcall	$0	–	-50,000	-100.0%	-0.00%	–
SCYX	Exit	SCYNEXIS INC	$0	–	-820,000	-100.0%	-0.04%	–
UROV	Exit	UROVANT SCIENCES LTD	$0	–	-100,000	-100.0%	-0.04%	–
CDTX	Exit	CIDARA THERAPEUTICS INC	$0	–	-300,000	-100.0%	-0.05%	–
MCRB	Exit	SERES THERAPEUTICS INC	$0	–	-220,000	-100.0%	-0.06%	–
MNLO	Exit	MENLO THERAPEUTICS INC	$0	–	-330,000	-100.0%	-0.12%	–
AGN	Exit	ALLERGAN PLC	$0	–	-17,665	-100.0%	-0.12%	–
VKTX	Exit	VIKING THERAPEUTICS INC	$0	–	-200,000	-100.0%	-0.13%	–
ITCI	Exit	INTRA CELLULAR THERAPIES INC	$0	–	-187,500	-100.0%	-0.15%	–
ADVM	Exit	ADVERUM BIOTECHNOLOGIES INC	$0	–	-900,000	-100.0%	-0.20%	–
CLSD	Exit	CLEARSIDE BIOMEDICAL INC	$0	–	-975,000	-100.0%	-0.22%	–
KURA	Exit	KURA ONCOLOGY INC	$0	–	-405,000	-100.0%	-0.26%	–
ENTA	Exit	ENANTA PHARMACEUTICALS INC	$0	–	-92,500	-100.0%	-0.29%	–
ELAN	Exit	ELANCO ANIMAL HEALTH INC	$0	–	-375,000	-100.0%	-0.47%	–
ECYT	Exit	ENDOCYTE INC	$0	–	-850,000	-100.0%	-0.55%	–
ARNA	Exit	ARENA PHARMACEUTICALS INC	$0	–	-375,000	-100.0%	-0.62%	–
ABBV	Exit	ABBVIE INC	$0	–	-325,000	-100.0%	-1.11%	–

Original filings

The following EDGAR filing(s) were analyzed to create this report:

View 13F-HR filed 2019-02-14

Signatures

The EDGAR filing(s) were signed by:

Nnamdi Etoh — Controller

Top long-term holdings

Name	Quarters owned	Latest quarter owned	Max weighting
INTUITIVE SURGICAL INC	40	Q3 2023	3.4%
NEUROCRINE BIOSCIENCES INC	39	Q3 2023	4.8%
PACIRA PHARMACEUTICALS INC	39	Q3 2023	2.6%
ULTRAGENYX PHARMACEUTICAL IN	39	Q3 2023	1.9%
ACADIA HEALTHCARE COMPANY IN	38	Q3 2023	4.4%
ASCENDIS PHARMA A/S	35	Q3 2023	1.3%
INVITAE CORP	35	Q3 2023	1.8%
BIOMARIN PHARMACEUTICAL INC	35	Q3 2023	1.3%
MACROGENICS INC	35	Q3 2023	0.5%
COLLEGIUM PHARMACEUTICAL INC	34	Q3 2023	2.1%

View Rock Springs Capital Management LP's complete holdings history.

Latest significant ownerships (13-D/G)

Rock Springs Capital Management LP Q4 2018 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
Aeglea BioTherapeutics, Inc.	February 14, 2023	3,413,906	5.6%
Compass Therapeutics, Inc.	February 14, 2023	5,333,188	4.2%
Mirum Pharmaceuticals, Inc.	February 14, 2023	1,795,733	4.9%
PhaseBio Pharmaceuticals Inc^{Sold out}	February 14, 2023	0	0.0%
Sierra Oncology, Inc.^{Sold out}	February 14, 2023	0	0.0%
ARDELYX, INC.^{Sold out}	February 15, 2022	0	0.0%
CHIASMA, INC^{Sold out}	February 15, 2022	0	0.0%
FIVE PRIME THERAPEUTICS, INC.^{Sold out}	February 15, 2022	0	0.0%
F-star Therapeutics, Inc.	February 15, 2022	751,889	3.6%
Protara Therapeutics, Inc.^{Sold out}	February 15, 2022	0	0.0%

View Rock Springs Capital Management LP's complete significant-ownership history.

Latest filings

Type	Filed
SC 13G/A	2024-04-05
13F-HR	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14

View Rock Springs Capital Management LP's complete filings history.

All filings

View complete filings history.

Compare quarters

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