Rock Springs Capital Management LP

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$1.19 Billion is the total value of Rock Springs Capital Management LP's 128 reported holdings in Q1 2016. The portfolio turnover from Q4 2015 to Q1 2016 was 16.7% .

All

			Value		Shares		↓ Weighting
AET		AETNA INC NEW	$46,176,000	+3.9%	411,000	0.0%	3.87%	+14.9%
AGN	Buy	ALLERGAN PLC	$45,833,000	-9.5%	171,000	+5.6%	3.84%	+0.1%
ACHC	Buy	ACADIA HEALTHCARE COMPANY IN	$41,305,000	-2.0%	749,500	+11.0%	3.46%	+8.3%
HCA		HCA HOLDINGS INC	$33,562,000	+15.4%	430,000	0.0%	2.81%	+27.6%
BXLT		BAXALTA INC	$32,724,000	+3.5%	810,000	0.0%	2.74%	+14.5%
ALXN	Buy	ALEXION PHARMACEUTICALS INC	$31,707,000	-13.9%	227,750	+18.0%	2.66%	-4.8%
PFE	Buy	PFIZER INC	$30,775,000	-2.2%	1,038,300	+6.5%	2.58%	+8.1%
GILD	Buy	GILEAD SCIENCES INC	$30,341,000	-7.8%	330,300	+1.5%	2.54%	+1.9%
AAAP	Buy	ADVANCED ACCELERATOR APPLICsponsored ads	$29,172,000	+16.6%	833,000	+4.1%	2.44%	+28.9%
RDUS	Buy	RADIUS HEALTH INC	$25,419,000	-30.9%	808,500	+35.3%	2.13%	-23.5%
ISRG	Buy	INTUITIVE SURGICAL INC	$25,244,000	+17.0%	42,000	+6.3%	2.12%	+29.4%
CELG	Buy	CELGENE CORP	$23,972,000	-13.0%	239,500	+4.1%	2.01%	-3.7%
WCG	Buy	WELLCARE HEALTH PLANS INC	$21,333,000	+27.2%	230,000	+7.2%	1.79%	+40.6%
TEVA	Buy	TEVA PHARMACEUTICAL INDS LTDadr	$21,136,000	-15.1%	395,000	+4.1%	1.77%	-6.1%
COLL	Buy	COLLEGIUM PHARMACEUTICAL INC	$20,782,000	-24.8%	1,145,000	+13.9%	1.74%	-16.9%
MDCO	Buy	MEDICINES CO	$20,079,000	-14.0%	632,000	+1.1%	1.68%	-4.9%
LLY	Buy	LILLY ELI & CO	$19,875,000	-14.5%	276,000	+0.0%	1.66%	-5.5%
PCRX	Buy	PACIRA PHARMACEUTICALS INC	$17,298,000	-13.4%	326,500	+25.6%	1.45%	-4.2%
ONCE	Buy	SPARK THERAPEUTICS INC	$17,131,000	-32.5%	580,500	+3.7%	1.44%	-25.4%
ACRS	Sell	ACLARIS THERAPEUTICS INC	$16,970,000	-29.7%	895,500	-0.1%	1.42%	-22.3%
ANTM	Buy	ANTHEM INC	$16,818,000	-0.2%	121,000	+0.2%	1.41%	+10.4%
CI		CIGNA CORPORATION	$16,743,000	-6.2%	122,000	0.0%	1.40%	+3.7%
TSRO	Buy	TESARO INC	$16,709,000	-4.4%	379,500	+13.6%	1.40%	+5.7%
NBIX	Buy	NEUROCRINE BIOSCIENCES INC	$15,998,000	-25.1%	404,500	+7.2%	1.34%	-17.2%
TMO	Buy	THERMO FISHER SCIENTIFIC INC	$14,187,000	+0.0%	100,200	+0.2%	1.19%	+10.6%
AMGN	Buy	AMGEN INC	$14,093,000	+7.3%	94,000	+16.2%	1.18%	+18.7%
BIIB	Buy	BIOGEN INC	$13,836,000	-10.8%	53,150	+4.9%	1.16%	-1.4%
PRTA	Buy	PROTHENA CORP PLC	$12,677,000	-24.9%	308,000	+24.2%	1.06%	-17.0%
MD	Buy	MEDNAX INC	$12,601,000	-8.9%	195,000	+1.0%	1.06%	+0.8%
TBPH	Buy	THERAVANCE BIOPHARMA INC	$12,229,000	+15.7%	650,500	+0.9%	1.02%	+28.0%
MCK	Buy	MCKESSON CORP	$12,187,000	-14.8%	77,500	+6.9%	1.02%	-5.7%
JAZZ	Buy	JAZZ PHARMACEUTICALS PLC	$11,162,000	-1.1%	85,500	+6.5%	0.94%	+9.4%
BMY	New	BRISTOL MYERS SQUIBB CO	$10,860,000	–	170,000	+100.0%	0.91%	–
PRAH		PRA HEALTH SCIENCES INC	$10,818,000	-5.5%	253,000	0.0%	0.91%	+4.4%
GWPH	Buy	GW PHARMACEUTICALS PLCads	$10,606,000	+31.7%	147,000	+26.7%	0.89%	+45.7%
PEN	Buy	PENUMBRA INC	$10,511,000	-4.7%	228,500	+11.5%	0.88%	+5.4%
WBA	New	WALGREENS BOOTS ALLIANCE INC	$10,404,000	–	123,500	+100.0%	0.87%	–
TXMD	Buy	THERAPEUTICSMD INC	$10,080,000	-18.0%	1,575,000	+32.9%	0.84%	-9.2%
ANAC	Buy	ANACOR PHARMACEUTICALS INC	$9,487,000	+9.1%	177,500	+130.5%	0.80%	+20.6%
INCY	Buy	INCYTE CORP	$9,457,000	-31.3%	130,500	+2.8%	0.79%	-24.1%
ACHN	Buy	ACHILLION PHARMACEUTICALS IN	$9,418,000	-21.0%	1,220,000	+10.4%	0.79%	-12.6%
GLPG		GALAPAGOS NVspon adr	$8,782,000	-33.5%	210,000	0.0%	0.74%	-26.5%
BMRN	Buy	BIOMARIN PHARMACEUTICAL INC	$8,516,000	+16.1%	103,250	+47.5%	0.71%	+28.4%
ARDX	Buy	ARDELYX INC	$8,239,000	-33.4%	1,060,400	+55.4%	0.69%	-26.4%
WMGI	Buy	WRIGHT MED GROUP N V	$8,134,000	-26.2%	490,000	+7.5%	0.68%	-18.3%
INOV	Sell	INOVALON HLDGS INC	$7,914,000	-2.5%	427,300	-10.5%	0.66%	+7.8%
HLS	Buy	HEALTHSOUTH CORP	$7,827,000	+15.3%	208,000	+6.7%	0.66%	+27.6%
NVTA	Buy	INVITAE CORP	$7,698,000	+50.5%	752,500	+20.8%	0.64%	+66.2%
JUNO		JUNO THERAPEUTICS INC	$7,504,000	-13.4%	197,001	0.0%	0.63%	-4.1%
RARE	Buy	ULTRAGENYX PHARMACEUTICAL IN	$7,502,000	-36.6%	118,500	+12.3%	0.63%	-29.9%
RTIX		RTI SURGICAL INC	$7,440,000	+0.8%	1,860,000	0.0%	0.62%	+11.2%
COO	Buy	COOPER COS INC	$7,329,000	+24.1%	47,600	+8.2%	0.61%	+37.4%
EPZM	Buy	EPIZYME INC	$7,139,000	+20.4%	589,000	+59.2%	0.60%	+33.2%
RTRX	Sell	RETROPHIN INC	$7,122,000	-45.3%	521,400	-22.8%	0.60%	-39.5%
MCRB	Buy	SERES THERAPEUTICS INC	$6,959,000	-19.2%	262,000	+6.8%	0.58%	-10.6%
EW	New	EDWARDS LIFESCIENCES CORP	$6,704,000	–	76,000	+100.0%	0.56%	–
VRTX	Buy	VERTEX PHARMACEUTICALS INC	$6,669,000	-27.1%	83,900	+15.3%	0.56%	-19.5%
ALKS	New	ALKERMES PLC	$6,650,000	–	194,500	+100.0%	0.56%	–
CRVS	New	CORVUS PHARMACEUTICALS INC	$6,625,000	–	456,887	+100.0%	0.56%	–
BGNE	New	BEIGENE LTDsponsored adr	$6,595,000	–	225,000	+100.0%	0.55%	–
XENT	Buy	INTERSECT ENT INC	$6,460,000	-14.9%	340,000	+0.8%	0.54%	-5.9%
ATHN	Buy	ATHENAHEALTH INC	$6,349,000	-0.1%	45,750	+15.8%	0.53%	+10.4%
ADAP		ADAPTIMMUNE THERAPEUTICS PLCsponds adr	$6,219,000	-32.6%	765,001	0.0%	0.52%	-25.5%
NVDQ	Buy	NOVADAQ TECHNOLOGIES INC	$6,155,000	-10.5%	555,000	+2.8%	0.52%	-1.0%
HTWR	Buy	HEARTWARE INTL INC	$6,064,000	-25.1%	193,000	+20.1%	0.51%	-17.3%
DERM		DERMIRA INC	$5,997,000	-40.3%	290,000	0.0%	0.50%	-34.0%
CHRS		COHERUS BIOSCIENCES INC	$5,987,000	-7.5%	282,000	0.0%	0.50%	+2.2%
REGN	Buy	REGENERON PHARMACEUTICALS	$5,947,000	-0.4%	16,500	+50.0%	0.50%	+9.9%
FPRX	Buy	FIVE PRIME THERAPEUTICS INC	$5,871,000	+4.8%	144,500	+7.0%	0.49%	+15.8%
INSYQ	Buy	INSYS THERAPEUTICS INC NEW	$5,844,000	-39.7%	365,500	+8.0%	0.49%	-33.2%
INSM	Buy	INSMED INC	$5,702,000	-27.4%	450,000	+4.0%	0.48%	-19.7%
EVHC	Buy	ENVISION HEALTHCARE HLDGS IN	$5,426,000	-14.7%	266,000	+8.6%	0.46%	-5.6%
CO		CHINA CORD BLOOD CORP	$5,342,000	-4.7%	880,000	0.0%	0.45%	+5.4%
ADRO		ADURO BIOTECH INC	$5,316,000	-54.5%	415,000	0.0%	0.44%	-49.7%
ITCI	Buy	INTRA CELLULAR THERAPIES INC	$5,213,000	-46.2%	187,500	+4.2%	0.44%	-40.5%
FOLD	Buy	AMICUS THERAPEUTICS INC	$5,184,000	-5.7%	613,500	+8.3%	0.43%	+4.3%
ASND		ASCENDIS PHARMA A Ssponsored adr	$5,009,000	+1.3%	270,000	0.0%	0.42%	+12.0%
XNPT		XENOPORT INC	$4,961,000	-17.9%	1,100,000	0.0%	0.42%	-9.2%
TNDM		TANDEM DIABETES CARE INC	$4,899,000	-26.3%	562,500	0.0%	0.41%	-18.5%
CRME		CARDIOME PHARMA CORP	$4,867,000	-49.6%	1,190,000	0.0%	0.41%	-44.2%
AGNPRA		ALLERGAN PLCpfd conv ser a	$4,585,000	-10.7%	5,000	0.0%	0.38%	-1.3%
CGEN	Buy	COMPUGEN LTDord	$4,576,000	-11.0%	820,000	+1.9%	0.38%	-1.8%
PTI	New	PROTEOSTASIS THERAPEUTICS IN	$4,531,000	–	470,000	+100.0%	0.38%	–
CHMA	Buy	CHIASMA INC	$4,511,000	-52.7%	492,500	+1.0%	0.38%	-47.7%
NVAX	Buy	NOVAVAX INC	$4,399,000	-31.9%	852,500	+10.7%	0.37%	-24.5%
FGEN	Buy	FIBROGEN INC	$4,343,000	-25.0%	204,000	+7.4%	0.36%	-17.1%
MGNX	Buy	MACROGENICS INC	$4,219,000	-37.5%	225,000	+3.2%	0.35%	-31.1%
AIMT	Buy	AIMMUNE THERAPEUTICS INC	$3,973,000	-17.1%	293,000	+12.8%	0.33%	-8.3%
AVXS	New	AVEXIS INC	$3,889,000	–	142,758	+100.0%	0.33%	–
PRGO		PERRIGO CO PLC	$3,838,000	-11.6%	30,000	0.0%	0.32%	-2.1%
GNCA		GENOCEA BIOSCIENCES INC	$3,715,000	+46.8%	480,000	0.0%	0.31%	+62.0%
KITE		KITE PHARMA INC	$3,673,000	-25.5%	80,000	0.0%	0.31%	-17.6%
OTIC	Buy	OTONOMY INC	$3,581,000	-34.7%	240,000	+21.5%	0.30%	-27.7%
PTLA	Buy	PORTOLA PHARMACEUTICALS INC	$3,570,000	-57.9%	175,000	+6.1%	0.30%	-53.5%
	New	MEDICINES COnote 2.500% 1/1	$3,405,000	–	3,000,000	+100.0%	0.28%	–
NBRV	Buy	NABRIVA THERAPEUTICS AGsponsored adr	$3,405,000	+51.7%	380,000	+61.7%	0.28%	+67.6%
PRTK	Buy	PARATEK PHARMACEUTICALS INC	$3,383,000	+478.3%	223,000	+623.4%	0.28%	+543.2%
CDTX		CIDARA THERAPEUTICS INC	$3,175,000	-26.0%	250,000	0.0%	0.27%	-18.2%
DVAX	Buy	DYNAVAX TECHNOLOGIES CORP	$3,175,000	-12.4%	165,000	+10.0%	0.27%	-3.3%
NVCR		NOVOCURE LTD	$3,103,000	-35.2%	214,316	0.0%	0.26%	-28.4%
GI		ENDOCHOICE HLDGS INC	$3,074,000	-37.6%	590,000	0.0%	0.26%	-30.8%
RIGL	Buy	RIGEL PHARMACEUTICALS INC	$3,045,000	-8.6%	1,464,050	+33.1%	0.26%	+0.8%
EARS	New	AURIS MED HLDG AG	$2,867,000	–	787,600	+100.0%	0.24%	–
SRPT	Buy	SAREPTA THERAPEUTICS INC	$2,557,000	-38.3%	131,000	+21.9%	0.21%	-31.8%
SCYX		SCYNEXIS INC	$2,559,000	-35.1%	635,000	0.0%	0.21%	-28.4%
CLVS		CLOVIS ONCOLOGY INC	$2,400,000	-45.1%	125,000	0.0%	0.20%	-39.5%
ALDR	New	ALDER BIOPHARMACEUTICALS INC	$2,388,000	–	97,500	+100.0%	0.20%	–
DBVT	Buy	DBV TECHNOLOGIES S Asponsored adr	$2,376,000	+161.7%	73,000	+192.0%	0.20%	+188.4%
VRX	Buy	VALEANT PHARMACEUTICALS INTL	$2,249,000	-73.6%	85,500	+2.2%	0.19%	-70.9%
OPHT	New	OPHTHOTECH CORP	$2,177,000	–	51,500	+100.0%	0.18%	–
DMTX		DIMENSION THERAPEUTICS INC	$2,125,000	-30.6%	271,370	0.0%	0.18%	-23.3%
EGLTQ		EGALET CORP	$2,058,000	-37.7%	300,000	0.0%	0.17%	-31.5%
NVLS		NIVALIS THERAPEUTICS INC	$2,039,000	-46.1%	489,000	0.0%	0.17%	-40.4%
ASMB	Buy	ASSEMBLY BIOSCIENCES INC	$1,958,000	-29.7%	390,000	+5.1%	0.16%	-22.3%
TTPH	Buy	TETRAPHASE PHARMACEUTICALS I	$1,852,000	-7.7%	400,000	+100.0%	0.16%	+2.0%
LIFE	Buy	ATYR PHARMA INC	$1,708,000	-58.1%	433,496	+4.4%	0.14%	-53.7%
CERU		CERULEAN PHARMA INC	$1,694,000	-3.2%	625,000	0.0%	0.14%	+6.8%
ANTH	Buy	ANTHERA PHARMACEUTICALS INC	$1,629,000	-7.6%	450,000	+18.4%	0.14%	+1.5%
INFI	Buy	INFINITY PHARMACEUTICALS INC	$1,423,000	-15.7%	270,000	+25.6%	0.12%	-7.0%
ICPT	Sell	INTERCEPT PHARMACEUTICALS IN	$1,285,000	-44.5%	10,000	-35.5%	0.11%	-38.3%
GBT	Buy	GLOBAL BLOOD THERAPEUTICS IN	$1,237,000	-45.7%	78,000	+10.6%	0.10%	-39.9%
OREX	Buy	OREXIGEN THERAPEUTICS INC	$930,000	-67.2%	1,653,000	+0.2%	0.08%	-63.7%
PBYI	Buy	PUMA BIOTECHNOLOGY INC	$925,000	+7.3%	31,500	+186.4%	0.08%	+20.0%
SPHS		SOPHIRIS BIO INC	$905,000	-20.5%	628,563	0.0%	0.08%	-11.6%
	New	WRIGHT MED GROUP INCnote 2.000% 2/1	$898,000	–	1,000,000	+100.0%	0.08%	–
BLUE		BLUEBIRD BIO INC	$850,000	-33.8%	20,000	0.0%	0.07%	-26.8%
PTLA	New	PORTOLA PHARMACEUTICALS INCcall	$714,000	–	35,000	+100.0%	0.06%	–
MIRN		MIRNA THERAPEUTICS INC	$656,000	-30.1%	150,000	0.0%	0.06%	-22.5%
PETX	Exit	ARATANA THERAPEUTICS INC	$0	–	-43,445	-100.0%	-0.02%	–
SRPT	Exit	SAREPTA THERAPEUTICS INCcall	$0	–	-53,300	-100.0%	-0.16%	–
DYAX	Exit	DYAX CORP	$0	–	-124,000	-100.0%	-0.35%	–
ABBV	Exit	ABBVIE INC	$0	–	-87,500	-100.0%	-0.39%	–
RLYP	Exit	RELYPSA INC	$0	–	-252,000	-100.0%	-0.54%	–
IDXX	Exit	IDEXX LABS INC	$0	–	-127,500	-100.0%	-0.70%	–

Original filings

The following EDGAR filing(s) were analyzed to create this report:

View 13F-HR filed 2016-05-16

Signatures

The EDGAR filing(s) were signed by:

Evans Apeadu — Chief Financial Officer/Chief Compliance Officer

Top long-term holdings

Name	Quarters owned	Latest quarter owned	Max weighting
INTUITIVE SURGICAL INC	40	Q3 2023	3.4%
NEUROCRINE BIOSCIENCES INC	39	Q3 2023	4.8%
PACIRA PHARMACEUTICALS INC	39	Q3 2023	2.6%
ULTRAGENYX PHARMACEUTICAL IN	39	Q3 2023	1.9%
ACADIA HEALTHCARE COMPANY IN	38	Q3 2023	4.4%
ASCENDIS PHARMA A/S	35	Q3 2023	1.3%
INVITAE CORP	35	Q3 2023	1.8%
BIOMARIN PHARMACEUTICAL INC	35	Q3 2023	1.3%
MACROGENICS INC	35	Q3 2023	0.5%
COLLEGIUM PHARMACEUTICAL INC	34	Q3 2023	2.1%

View Rock Springs Capital Management LP's complete holdings history.

Latest significant ownerships (13-D/G)

Rock Springs Capital Management LP Q1 2016 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
	Filed	Shares	Percentage
Aeglea BioTherapeutics, Inc.	February 14, 2023	3,413,906	5.6%
Compass Therapeutics, Inc.	February 14, 2023	5,333,188	4.2%
Mirum Pharmaceuticals, Inc.	February 14, 2023	1,795,733	4.9%
PhaseBio Pharmaceuticals Inc^{Sold out}	February 14, 2023	0	0.0%
Sierra Oncology, Inc.^{Sold out}	February 14, 2023	0	0.0%
ARDELYX, INC.^{Sold out}	February 15, 2022	0	0.0%
CHIASMA, INC^{Sold out}	February 15, 2022	0	0.0%
FIVE PRIME THERAPEUTICS, INC.^{Sold out}	February 15, 2022	0	0.0%
F-star Therapeutics, Inc.	February 15, 2022	751,889	3.6%
Protara Therapeutics, Inc.^{Sold out}	February 15, 2022	0	0.0%

View Rock Springs Capital Management LP's complete significant-ownership history.

Latest filings

Type	Filed
SC 13G	2024-05-01
SC 13G/A	2024-04-05
13F-HR	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14
SC 13G/A	2024-02-14

View Rock Springs Capital Management LP's complete filings history.

All filings

View complete filings history.

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