$659 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 108 reported holdings in Q1 2018. The portfolio turnover from Q4 2017 to Q1 2018 was 100.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -800 | -100.0% | -0.00% | – |
| CMG | Exit | CHIPOTLE MEXICAN GRILL INC | $0 | – | -400 | -100.0% | -0.01% | – |
| TRIP | Exit | TRIPADVISOR INC | $0 | – | -4,000 | -100.0% | -0.02% | – |
| LVNTA | Exit | LIBERTY INTERACTIVE CORP | $0 | – | -3,000 | -100.0% | -0.02% | – |
| LOW | Exit | LOWES COS INC | $0 | – | -2,600 | -100.0% | -0.03% | – |
| ECL | Exit | ECOLAB INC | $0 | – | -2,000 | -100.0% | -0.03% | – |
| SAGE | Exit | SAGE THERAPEUTICS INCput | $0 | – | -2,400 | -100.0% | -0.05% | – |
| TJX | Exit | TJX COS INC NEW | $0 | – | -5,800 | -100.0% | -0.05% | – |
| CATB | Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -328,030 | -100.0% | -0.06% | – |
| ALBO | Exit | ALBIREO PHARMA INC | $0 | – | -35,431 | -100.0% | -0.11% | – |
| SBPH | Exit | SPRING BK PHARMACEUTICALS IN | $0 | – | -74,309 | -100.0% | -0.12% | – |
| ITEK | Exit | INOTEK PHARMACEUTICALS CORP | $0 | – | -100,441 | -100.0% | -0.12% | – |
| ACOR | Exit | ACORDA THERAPEUTICS INC | $0 | – | -50,000 | -100.0% | -0.13% | – |
| ALRN | Exit | AILERON THERAPEUTICS INC | $0 | – | -125,000 | -100.0% | -0.16% | – |
| AXSM | Exit | AXSOME THERAPEUTICS INC | $0 | – | -301,000 | -100.0% | -0.20% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -210,000 | -100.0% | -0.20% | – |
| OVID | Exit | OVID THERAPEUTICS INC | $0 | – | -180,674 | -100.0% | -0.21% | – |
| KALA | Exit | KALA PHARMACEUTICALS INC | $0 | – | -100,000 | -100.0% | -0.22% | – |
| AAP | Exit | ADVANCE AUTO PARTS INCcall | $0 | – | -21,000 | -100.0% | -0.25% | – |
| MYL | Exit | MYLAN N Vcall | $0 | – | -50,000 | -100.0% | -0.25% | – |
| GLMD | Exit | GALMED PHARMACEUTICALS LTD | $0 | – | -238,095 | -100.0% | -0.25% | – |
| ORBK | Exit | ORBOTECH LTDord | $0 | – | -43,488 | -100.0% | -0.26% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -240,000 | -100.0% | -0.26% | – |
| SELB | Exit | SELECTA BIOSCIENCES INC | $0 | – | -228,534 | -100.0% | -0.26% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDsponsored adr | $0 | – | -118,750 | -100.0% | -0.26% | – |
| CPRX | Exit | CATALYST PHARMACEUTICALS INC | $0 | – | -576,825 | -100.0% | -0.26% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -345,000 | -100.0% | -0.27% | – |
| PANW | Exit | PALO ALTO NETWORKS INC | $0 | – | -16,055 | -100.0% | -0.27% | – |
| SMMT | Exit | SUMMIT THERAPEUTICS PLCspons ads | $0 | – | -212,018 | -100.0% | -0.28% | – |
| CASC | Exit | CASCADIAN THERAPEUTICS INC | $0 | – | -681,210 | -100.0% | -0.30% | – |
| CRBP | Exit | CORBUS PHARMACEUTICALS HLDGS | $0 | – | -375,000 | -100.0% | -0.31% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -37,000 | -100.0% | -0.34% | – |
| TXMD | Exit | THERAPEUTICSMD INC | $0 | – | -479,980 | -100.0% | -0.34% | – |
| SVRA | Exit | SAVARA INC | $0 | – | -200,000 | -100.0% | -0.35% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -35,000 | -100.0% | -0.37% | – |
| EDGE | Exit | EDGE THERAPEUTICS INC | $0 | – | -333,737 | -100.0% | -0.37% | – |
| IMGN | Exit | IMMUNOGEN INC | $0 | – | -500,000 | -100.0% | -0.38% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -35,000 | -100.0% | -0.41% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -1,300,000 | -100.0% | -0.43% | – |
| CTSH | Exit | COGNIZANT TECHNOLOGY SOLUTIOcl a | $0 | – | -55,086 | -100.0% | -0.46% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS IN | $0 | – | -100,000 | -100.0% | -0.46% | – |
| HON | Exit | HONEYWELL INTL INC | $0 | – | -26,750 | -100.0% | -0.48% | – |
| XLF | Exit | SELECT SECTOR SPDR TRsbi int-finl | $0 | – | -155,000 | -100.0% | -0.51% | – |
| FLKS | Exit | FLEX PHARMA INC | $0 | – | -241,211 | -100.0% | -0.51% | – |
| WIX | Exit | WIX COM LTD | $0 | – | -78,180 | -100.0% | -0.53% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -300,000 | -100.0% | -0.55% | – |
| INCY | Exit | INCYTE CORP | $0 | – | -50,000 | -100.0% | -0.56% | – |
| INCY | Exit | INCYTE CORPput | $0 | – | -50,000 | -100.0% | -0.56% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -30,000 | -100.0% | -0.58% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -170,000 | -100.0% | -0.60% | – |
| ONCE | Exit | SPARK THERAPEUTICS INC | $0 | – | -100,000 | -100.0% | -0.60% | – |
| NOMD | Exit | NOMAD FOODS LTD | $0 | – | -340,162 | -100.0% | -0.68% | – |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -205,000 | -100.0% | -0.90% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -344,300 | -100.0% | -1.08% | – |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INC | $0 | – | -210,000 | -100.0% | -1.20% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -85,823 | -100.0% | -1.51% | – |
| CELJF | Exit | CELLCOM ISRAEL LTD | $0 | – | -1,359,744 | -100.0% | -1.64% | – |
| IBB | Exit | ISHARES TRput | $0 | – | -500,000 | -100.0% | -6.26% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2018-05-10
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-05-15 |
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.