$784 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 128 reported holdings in Q3 2015. The portfolio turnover from Q2 2015 to Q3 2015 was 49.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PFE | Sell | PFIZER INC | $18,030,000 | -38.5% | 574,013 | -34.3% | 2.30% | -19.9% |
| ABBV | Sell | ABBVIE INC | $17,792,000 | -34.9% | 327,000 | -19.7% | 2.27% | -15.3% |
| CELG | Sell | CELGENE CORP | $12,980,000 | -29.9% | 120,000 | -25.0% | 1.66% | -8.7% |
| GILD | Sell | GILEAD SCIENCES INC | $11,783,000 | -68.6% | 120,000 | -62.5% | 1.50% | -59.0% |
| CLVS | Sell | CLOVIS ONCOLOGY INC | $9,656,000 | -8.4% | 105,000 | -12.5% | 1.23% | +19.3% |
| AMGN | Sell | AMGEN INC | $6,944,000 | -24.9% | 50,200 | -16.6% | 0.89% | -2.1% |
| CHKP | Sell | CHECK POINT SOFTWARE TECH LTord | $5,738,000 | -20.8% | 72,327 | -20.6% | 0.73% | +3.1% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $4,337,000 | -31.9% | 310,000 | -31.1% | 0.55% | -11.4% |
| ITCI | Sell | INTRA CELLULAR THERAPIES INC | $4,220,000 | +3.2% | 105,400 | -17.7% | 0.54% | +34.2% |
| KMPH | Sell | KEMPHARM INC | $3,961,000 | -9.2% | 204,393 | -13.9% | 0.50% | +18.3% |
| GWPH | Sell | GW PHARMACEUTICALS PLCads | $3,938,000 | -26.3% | 43,100 | -0.9% | 0.50% | -4.0% |
| AMAG | Sell | AMAG PHARMACEUTICALS INC | $3,386,000 | -45.7% | 85,230 | -5.5% | 0.43% | -29.2% |
| CPRX | Sell | CATALYST PHARMACEUTICALS INC | $3,300,000 | -33.4% | 1,100,000 | -8.3% | 0.42% | -13.2% |
| FWP | Sell | FORWARD PHARMA A/Ssponsored adr | $3,181,000 | -44.3% | 135,000 | -10.0% | 0.41% | -27.4% |
| INSM | Sell | INSMED INC | $3,064,000 | -41.6% | 165,000 | -23.3% | 0.39% | -23.9% |
| CYNA | Sell | CYNAPSUS THERAPEUTICS INC | $3,059,000 | -42.5% | 188,930 | -40.3% | 0.39% | -25.1% |
| RARE | Sell | ULTRAGENYX PHARMACEUTICAL IN | $2,957,000 | -39.5% | 30,700 | -35.6% | 0.38% | -21.1% |
| VRX | Sell | VALEANT PHARMACEUTICALS INTL | $2,809,000 | -72.4% | 15,750 | -65.6% | 0.36% | -64.0% |
| ITEK | Sell | INOTEK PHARMACEUTICALS CORP | $2,773,000 | +48.9% | 295,000 | -22.4% | 0.35% | +94.5% |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $2,754,000 | -7.9% | 80,000 | -15.8% | 0.35% | +19.8% |
| NVLS | Sell | NIVALIS THERAPEUTICS INC | $2,616,000 | -32.3% | 201,720 | -20.9% | 0.33% | -11.6% |
| CATB | Sell | CATABASIS PHARMACEUTICALS IN | $2,595,000 | -48.7% | 327,476 | -26.6% | 0.33% | -33.3% |
| CYTK | Sell | CYTOKINETICS INC | $2,490,000 | -12.3% | 372,250 | -11.8% | 0.32% | +14.4% |
| DVAX | Sell | DYNAVAX TECHNOLOGIES CORP | $2,454,000 | -30.2% | 100,000 | -33.3% | 0.31% | -9.0% |
| ELLO | Sell | ELLOMAY CAPITAL LIMITED | $2,335,000 | -7.3% | 221,097 | -10.4% | 0.30% | +20.6% |
| PRTA | Sell | PROTHENA CORP PLC | $2,046,000 | -66.3% | 45,133 | -60.8% | 0.26% | -56.1% |
| RLYP | Sell | RELYPSA INC | $1,981,000 | -54.6% | 107,000 | -18.9% | 0.25% | -40.9% |
| SGEN | Sell | SEATTLE GENETICS INC | $1,928,000 | -71.5% | 50,000 | -64.3% | 0.25% | -63.0% |
| NVS | Sell | NOVARTIS A Gsponsored adr | $1,838,000 | -81.3% | 20,000 | -80.0% | 0.24% | -75.6% |
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $1,766,000 | -61.3% | 55,000 | -63.3% | 0.22% | -49.7% |
| PIRS | Sell | PIERIS PHARMACEUTICALS INC | $1,647,000 | -50.1% | 900,000 | -25.0% | 0.21% | -35.0% |
| ARRY | Sell | ARRAY BIOPHARMA INC | $1,596,000 | -72.3% | 350,000 | -56.2% | 0.20% | -63.9% |
| MRNS | Sell | MARINUS PHARMACEUTICALS INC | $1,352,000 | -61.0% | 162,120 | -45.7% | 0.17% | -49.3% |
| ORBK | Sell | ORBOTECH LTDord | $1,213,000 | -72.9% | 78,482 | -63.5% | 0.16% | -64.6% |
| WIX | Sell | WIX COM LTD | $1,013,000 | -64.4% | 58,160 | -51.7% | 0.13% | -53.6% |
| CHTR | Sell | CHARTER COMMUNICATIONS INC Dcl a new | $708,000 | -58.9% | 4,026 | -60.0% | 0.09% | -46.7% |
| 3106PS | Sell | DELPHI AUTOMOTIVE PLC | $696,000 | -84.6% | 9,150 | -82.8% | 0.09% | -79.9% |
| AOS | Sell | SMITH A O | $681,000 | -81.3% | 10,441 | -79.4% | 0.09% | -75.6% |
| SAGE | Sell | SAGE THERAPEUTICS INC | $339,000 | -90.3% | 8,000 | -83.3% | 0.04% | -87.5% |
| NICE | Sell | NICE SYS LTDsponsored adr | $255,000 | -78.0% | 4,525 | -75.2% | 0.03% | -71.1% |
| PTCT | Sell | PTC THERAPEUTICS INC | $107,000 | -96.7% | 4,000 | -94.0% | 0.01% | -95.5% |
| LMNS | Exit | LUMENIS LTD | $0 | – | -245 | -100.0% | 0.00% | – |
| TTHI | Exit | TRANSITION THERAPEUTICS INC | $0 | – | -70,273 | -100.0% | -0.01% | – |
| PRGO | Exit | PERRIGO CO PLC | $0 | – | -273 | -100.0% | -0.02% | – |
| EARS | Exit | AURIS MED HLDG AG | $0 | – | -63,967 | -100.0% | -0.03% | – |
| ZSAN | Exit | ZOSANO PHARMA CORP | $0 | – | -62,300 | -100.0% | -0.04% | – |
| GALT | Exit | GALECTIN THERAPEUTICS INC | $0 | – | -205,000 | -100.0% | -0.06% | – |
| SPNS | Exit | SAPIENS INTL CORP N V | $0 | – | -56,420 | -100.0% | -0.06% | – |
| IPXL | Exit | IMPAX LABORATORIES INC | $0 | – | -15,000 | -100.0% | -0.07% | – |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -245,000 | -100.0% | -0.10% | – |
| VFC | Exit | V F CORP | $0 | – | -17,600 | -100.0% | -0.12% | – |
| BRCM | Exit | BROADCOM CORPcl a | $0 | – | -24,894 | -100.0% | -0.13% | – |
| Exit | APTOSE BIOSCIENCES INC | $0 | – | -221,096 | -100.0% | -0.14% | – | |
| TW | Exit | TOWERS WATSON & COcl a | $0 | – | -12,807 | -100.0% | -0.16% | – |
| TTPH | Exit | TETRAPHASE PHARMACEUTICALS I | $0 | – | -49,500 | -100.0% | -0.23% | – |
| SNA | Exit | SNAP ON INC | $0 | – | -15,340 | -100.0% | -0.24% | – |
| TRVN | Exit | TREVENA INC | $0 | – | -410,000 | -100.0% | -0.25% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -113,000 | -100.0% | -0.25% | – |
| Exit | MEDICINES COcall | $0 | – | -1,000 | -100.0% | -0.28% | – | |
| AAPL | Exit | APPLE INC | $0 | – | -23,223 | -100.0% | -0.28% | – |
| TKMR | Exit | TEKMIRA PHARMACEUTICALS CORP | $0 | – | -255,000 | -100.0% | -0.30% | – |
| MLNX | Exit | MELLANOX TECHNOLOGIES LTD | $0 | – | -62,850 | -100.0% | -0.30% | – |
| AGTC | Exit | APPLIED GENETIC TECHNOL CORP | $0 | – | -200,124 | -100.0% | -0.30% | – |
| PAY | Exit | VERIFONE SYS INC | $0 | – | -93,055 | -100.0% | -0.31% | – |
| OCUL | Exit | OCULAR THERAPEUTIX INC | $0 | – | -160,000 | -100.0% | -0.33% | – |
| KRE | Exit | SPDR SERIES TRUSTs&p regl bkg | $0 | – | -80,080 | -100.0% | -0.35% | – |
| SNSS | Exit | SUNESIS PHARMACEUTICALS INC | $0 | – | -1,235,000 | -100.0% | -0.36% | – |
| RCPT | Exit | RECEPTOS INC | $0 | – | -20,000 | -100.0% | -0.37% | – |
| MDVN | Exit | MEDIVATION INC | $0 | – | -34,115 | -100.0% | -0.38% | – |
| FEZ | Exit | SPDR INDEX SHS FDSeuro stoxx 50 | $0 | – | -104,920 | -100.0% | -0.38% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -180,000 | -100.0% | -0.50% | – |
| EWG | Exit | ISHARESmsci germany etf | $0 | – | -192,630 | -100.0% | -0.53% | – |
| BCOMF | Exit | B COMMUNICATIONS LTD | $0 | – | -5,977,000 | -100.0% | -0.63% | – |
| VRNT | Exit | VERINT SYS INC | $0 | – | -139,434 | -100.0% | -0.83% | – |
| CXRX | Exit | CONCORDIA HEALTHCARE CORP | $0 | – | -100,000 | -100.0% | -0.88% | – |
| Exit | BIOMARIN PHARMACEUTICAL INCcall | $0 | – | -1,000 | -100.0% | -1.34% | – | |
| Exit | PERRIGO CO PLCcall | $0 | – | -1,000 | -100.0% | -1.81% | – | |
| MRK | Exit | MERCK & CO INC NEW | $0 | – | -400,000 | -100.0% | -2.23% | – |
| Exit | TEVA PHARMACEUTICAL INDS LTDcall | $0 | – | -6,500 | -100.0% | -3.76% | – | |
| Exit | ISHARES TRput | $0 | – | -13,865 | -100.0% | -16.96% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2015-11-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-05-15 |
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.