$784 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 128 reported holdings in Q3 2015. The portfolio turnover from Q2 2015 to Q3 2015 was 116.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Buy | SELECT SECTOR SPDR TRput | $66,230,000 | +196.8% | 10,000 | +233.3% | 8.45% | +286.6% | |
| New | SPDR S&P 500 ETF TRput | $46,969,000 | – | 2,451 | +100.0% | 5.99% | – | |
| TEVA | Buy | TEVA PHARMACEUTICAL INDS LTDadr | $42,509,000 | +305.7% | 752,905 | +324.7% | 5.42% | +428.7% |
| Buy | SPDR SERIES TRUSTput | $37,350,000 | -26.0% | 6,000 | +200.0% | 4.76% | -3.6% | |
| Buy | ISHARES TRput | $30,333,000 | +9.6% | 1,000 | +33.3% | 3.87% | +42.8% | |
| ESLT | New | ELBIT SYS LTDord | $29,169,000 | – | 100,618 | +100.0% | 3.72% | – |
| BIIB | Buy | BIOGEN INC | $24,804,000 | +1.1% | 85,000 | +40.0% | 3.16% | +31.7% |
| ORA | Buy | ORMAT TECHNOLOGIES INC | $17,551,000 | +55.2% | 132,659 | +65.6% | 2.24% | +102.1% |
| SHPG | Buy | SHIRE PLCsponsored adr | $13,252,000 | +93.0% | 169,751 | +26.0% | 1.69% | +151.3% |
| BMRN | Buy | BIOMARIN PHARMACEUTICAL INC | $13,165,000 | +60.4% | 125,000 | +108.3% | 1.68% | +109.0% |
| New | MYLAN N Vcall | $12,078,000 | – | 3,000 | +100.0% | 1.54% | – | |
| INCY | New | INCYTE CORP | $11,033,000 | – | 100,000 | +100.0% | 1.41% | – |
| BMY | Buy | BRISTOL MYERS SQUIBB CO | $8,880,000 | +33.5% | 150,000 | +50.0% | 1.13% | +73.8% |
| CELJF | New | CELLCOM ISRAEL LTD | $8,793,000 | – | 357,452 | +100.0% | 1.12% | – |
| PRGO | New | PERRIGO CO PLCcall | $8,603,000 | – | 547 | +100.0% | 1.10% | – |
| MYL | Buy | MYLAN N V | $8,052,000 | -32.2% | 200,000 | +14.3% | 1.03% | -11.7% |
| ACOR | Buy | ACORDA THERAPEUTICS INC | $7,158,000 | +43.2% | 270,000 | +80.0% | 0.91% | +86.3% |
| New | HORIZON PHARMA PLCcall | $6,937,000 | – | 3,500 | +100.0% | 0.88% | – | |
| DEPO | Buy | DEPOMED INC | $6,786,000 | +75.7% | 360,000 | +100.0% | 0.87% | +129.1% |
| XLY | New | SELECT SECTOR SPDR TRsbi cons discr | $6,625,000 | – | 89,216 | +100.0% | 0.84% | – |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $5,474,000 | – | 35,000 | +100.0% | 0.70% | – |
| TSRO | Buy | TESARO INC | $4,712,000 | -8.4% | 117,500 | +34.3% | 0.60% | +19.2% |
| EGLTQ | New | EGALET CORP | $4,284,000 | – | 325,000 | +100.0% | 0.55% | – |
| Buy | PTC THERAPEUTICS INCcall | $4,272,000 | +47.9% | 1,600 | +166.7% | 0.54% | +92.6% | |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $4,166,000 | – | 40,000 | +100.0% | 0.53% | – |
| PTLA | Buy | PORTOLA PHARMACEUTICALS INC | $4,049,000 | +3.4% | 95,000 | +10.5% | 0.52% | +34.6% |
| HZNP | New | HORIZON PHARMA PLC | $3,964,000 | – | 200,000 | +100.0% | 0.51% | – |
| CNCE | Buy | CONCERT PHARMACEUTICALS INC | $3,754,000 | +1490.7% | 200,000 | +1161.2% | 0.48% | +1982.6% |
| MGNX | Buy | MACROGENICS INC | $3,641,000 | +12.8% | 170,000 | +100.0% | 0.46% | +47.2% |
| SBUX | Buy | STARBUCKS CORP | $3,563,000 | +24.0% | 62,683 | +17.0% | 0.46% | +61.9% |
| RPTP | Buy | RAPTOR PHARMACEUTICAL CORP | $3,534,000 | +8.4% | 584,089 | +182.9% | 0.45% | +41.4% |
| New | ARRAY BIOPHARMA INCcall | $3,420,000 | – | 7,500 | +100.0% | 0.44% | – | |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $3,214,000 | -27.5% | 40,000 | +8.1% | 0.41% | -5.5% |
| CARA | Buy | CARA THERAPEUTICS INC | $3,141,000 | +454.0% | 219,800 | +370.7% | 0.40% | +616.1% |
| ARWR | Buy | ARROWHEAD RESH CORP | $3,110,000 | -8.4% | 540,000 | +13.7% | 0.40% | +19.2% |
| ABUS | New | ARBUTUS BIOPHARMA CORP | $3,075,000 | – | 505,000 | +100.0% | 0.39% | – |
| RTRX | New | RETROPHIN INC | $3,039,000 | – | 150,000 | +100.0% | 0.39% | – |
| TXMD | Buy | THERAPEUTICSMD INC | $3,003,000 | -7.4% | 512,500 | +24.2% | 0.38% | +20.4% |
| TJX | New | TJX COS INC NEW | $2,964,000 | – | 41,496 | +100.0% | 0.38% | – |
| ONCE | New | SPARK THERAPEUTICS INC | $2,921,000 | – | 70,000 | +100.0% | 0.37% | – |
| EXEL | Buy | EXELIXIS INC | $2,805,000 | +86.5% | 500,000 | +25.0% | 0.36% | +143.5% |
| ISIS | Buy | ISIS PHARMACEUTICALS INC | $2,749,000 | -0.5% | 68,000 | +41.7% | 0.35% | +29.5% |
| PTN | Buy | PALATIN TECHNOLOGIES INC | $2,720,000 | +20.3% | 3,358,483 | +32.2% | 0.35% | +57.0% |
| FPRX | Buy | FIVE PRIME THERAPEUTICS INC | $2,693,000 | -13.3% | 175,000 | +40.0% | 0.34% | +13.2% |
| GNCA | Buy | GENOCEA BIOSCIENCES INC | $2,584,000 | -37.7% | 377,200 | +24.8% | 0.33% | -18.7% |
| MDLZ | New | MONDELEZ INTL INCcl a | $2,490,000 | – | 59,475 | +100.0% | 0.32% | – |
| KERX | New | KERYX BIOPHARMACEUTICALS INC | $2,464,000 | – | 700,000 | +100.0% | 0.31% | – |
| ABEO | New | ABEONA THERAPEUTICS INC | $2,430,000 | – | 600,000 | +100.0% | 0.31% | – |
| PTNR | New | PARTNER COMMUNICATIONS CO LTadr | $2,416,000 | – | 617,951 | +100.0% | 0.31% | – |
| CEMP | New | CEMPRA INC | $2,088,000 | – | 75,000 | +100.0% | 0.27% | – |
| IMDZ | Buy | IMMUNE DESIGN CORP | $2,074,000 | -28.3% | 170,000 | +21.4% | 0.26% | -6.4% |
| AEGR | New | AEGERION PHARMACEUTICALS INC | $2,040,000 | – | 150,000 | +100.0% | 0.26% | – |
| WAB | Buy | WABTEC CORP | $2,002,000 | -5.0% | 22,735 | +1.7% | 0.26% | +23.8% |
| EPZM | New | EPIZYME INC | $1,929,000 | – | 150,000 | +100.0% | 0.25% | – |
| New | NEURODERM LTD | $1,757,000 | – | 85,000 | +100.0% | 0.22% | – | |
| PANW | New | PALO ALTO NETWORKS INC | $1,720,000 | – | 10,002 | +100.0% | 0.22% | – |
| NBRV | New | NABRIVA THERAPEUTICS AGsponsored adr | $1,663,000 | – | 175,000 | +100.0% | 0.21% | – |
| ZGNX | New | ZOGENIX INC | $1,620,000 | – | 120,000 | +100.0% | 0.21% | – |
| OCRX | New | OCERA THERAPEUTICS INC | $1,580,000 | – | 500,000 | +100.0% | 0.20% | – |
| ZFGN | New | ZAFGEN INC | $1,278,000 | – | 40,000 | +100.0% | 0.16% | – |
| HRTX | New | HERON THERAPEUTICS INC | $1,220,000 | – | 50,000 | +100.0% | 0.16% | – |
| ANAC | New | ANACOR PHARMACEUTICALS INC | $1,177,000 | – | 10,000 | +100.0% | 0.15% | – |
| NVAX | New | NOVAVAX INC | $1,061,000 | – | 150,000 | +100.0% | 0.14% | – |
| AXTA | New | AXALTA COATING SYS LTD | $1,029,000 | – | 40,626 | +100.0% | 0.13% | – |
| AIMT | New | AIMMUNE THERAPEUTICS INC | $5,000 | – | 200 | +100.0% | 0.00% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2015-11-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-05-15 |
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.