$1.02 Billion is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 133 reported holdings in Q2 2015. The portfolio turnover from Q1 2015 to Q2 2015 was 55.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| PFE | Sell | PFIZER INC | $29,306,000 | -17.7% | 874,013 | -14.6% | 2.87% | -22.6% |
| MYL | Sell | MYLAN N V | $11,876,000 | -26.5% | 175,000 | -35.7% | 1.16% | -30.8% |
| TEVA | Sell | TEVA PHARMACEUTICAL INDS LTDadr | $10,478,000 | -58.2% | 177,300 | -56.0% | 1.03% | -60.7% |
| AMGN | Sell | AMGEN INC | $9,242,000 | -51.9% | 60,200 | -49.9% | 0.90% | -54.8% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $8,207,000 | -17.7% | 60,000 | -25.0% | 0.80% | -22.5% |
| SGEN | Sell | SEATTLE GENETICS INC | $6,776,000 | -4.2% | 140,000 | -30.0% | 0.66% | -9.8% |
| ALDR | Sell | ALDER BIOPHARMACEUTICALS INC | $6,621,000 | +52.9% | 125,000 | -16.7% | 0.65% | +43.9% |
| VNDA | Sell | VANDA PHARMACEUTICALS INC | $6,515,000 | +28.9% | 513,390 | -5.5% | 0.64% | +21.3% |
| AMAG | Sell | AMAG PHARMACEUTICALS INC | $6,231,000 | -43.1% | 90,230 | -54.9% | 0.61% | -46.4% |
| ARRY | Sell | ARRAY BIOPHARMA INC | $5,768,000 | -15.3% | 800,000 | -13.4% | 0.56% | -20.3% |
| FWP | Sell | FORWARD PHARMA A/Ssponsored adr | $5,708,000 | +12.0% | 150,000 | -16.7% | 0.56% | +5.3% |
| INSM | Sell | INSMED INC | $5,250,000 | +1.0% | 215,000 | -14.0% | 0.51% | -5.0% |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $5,017,000 | -40.4% | 28,840 | -41.0% | 0.49% | -44.0% |
| BLCM | Sell | BELLICUM PHARMACEUTICALS INC | $4,924,000 | -13.5% | 231,514 | -7.2% | 0.48% | -18.7% |
| RLYP | Sell | RELYPSA INC | $4,368,000 | -10.3% | 132,000 | -2.2% | 0.43% | -15.6% |
| ITCI | Sell | INTRA CELLULAR THERAPIES INC | $4,090,000 | +14.2% | 128,000 | -14.7% | 0.40% | +7.5% |
| PTLA | Sell | PORTOLA PHARMACEUTICALS INC | $3,917,000 | +3.2% | 86,000 | -14.0% | 0.38% | -2.8% |
| MDVN | Sell | MEDIVATION INC | $3,896,000 | -16.4% | 34,115 | -5.5% | 0.38% | -21.2% |
| DEPO | Sell | DEPOMED INC | $3,863,000 | -13.8% | 180,000 | -10.0% | 0.38% | -19.1% |
| SNSS | Sell | SUNESIS PHARMACEUTICALS INC | $3,717,000 | +16.7% | 1,235,000 | -5.0% | 0.36% | +9.6% |
| AOS | Sell | SMITH A O | $3,644,000 | -9.9% | 50,620 | -17.8% | 0.36% | -15.2% |
| SAGE | Sell | SAGE THERAPEUTICS INC | $3,504,000 | +6.1% | 48,000 | -27.0% | 0.34% | -0.3% |
| KITE | Sell | KITE PHARMA INC | $3,473,000 | -8.7% | 56,970 | -13.6% | 0.34% | -14.1% |
| PTCT | Sell | PTC THERAPEUTICS INC | $3,201,000 | -24.9% | 66,500 | -5.0% | 0.31% | -29.3% |
| AGTC | Sell | APPLIED GENETIC TECHNOL CORP | $3,070,000 | -34.7% | 200,124 | -14.9% | 0.30% | -38.4% |
| TKMR | Sell | TEKMIRA PHARMACEUTICALS CORP | $3,024,000 | -42.0% | 255,000 | -14.6% | 0.30% | -45.5% |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $2,990,000 | +2.0% | 95,000 | -5.0% | 0.29% | -3.9% |
| AAPL | Sell | APPLE INC | $2,913,000 | -45.2% | 23,223 | -45.7% | 0.28% | -48.6% |
| SBUX | Sell | STARBUCKS CORP | $2,873,000 | -30.5% | 53,583 | -38.6% | 0.28% | -34.7% |
| TTPH | Sell | TETRAPHASE PHARMACEUTICALS I | $2,348,000 | -14.6% | 49,500 | -34.0% | 0.23% | -19.6% |
| ITEK | Sell | INOTEK PHARMACEUTICALS CORP | $1,862,000 | -14.1% | 380,000 | -5.0% | 0.18% | -19.5% |
| TW | Sell | TOWERS WATSON & COcl a | $1,611,000 | -68.2% | 12,807 | -66.6% | 0.16% | -70.0% |
| EXEL | Sell | EXELIXIS INC | $1,504,000 | +17.0% | 400,000 | -20.0% | 0.15% | +9.7% |
| BRCM | Sell | BROADCOM CORPcl a | $1,282,000 | -70.6% | 24,894 | -75.3% | 0.13% | -72.2% |
| VFC | Sell | V F CORP | $1,227,000 | -61.4% | 17,600 | -58.3% | 0.12% | -63.7% |
| IMMU | Sell | IMMUNOMEDICS INC | $995,000 | -13.4% | 245,000 | -18.3% | 0.10% | -19.2% |
| GNVC | Sell | GENVEC INC | $735,000 | -52.9% | 360,325 | -31.8% | 0.07% | -55.6% |
| IPXL | Sell | IMPAX LABORATORIES INC | $689,000 | -85.3% | 15,000 | -85.0% | 0.07% | -86.3% |
| GALT | Sell | GALECTIN THERAPEUTICS INC | $560,000 | -62.9% | 205,000 | -54.4% | 0.06% | -65.0% |
| ZSAN | Sell | ZOSANO PHARMA CORP | $452,000 | -75.8% | 62,300 | -66.3% | 0.04% | -77.3% |
| EARS | Sell | AURIS MED HLDG AG | $316,000 | -68.3% | 63,967 | -65.7% | 0.03% | -70.2% |
| PRGO | Sell | PERRIGO CO PLC | $246,000 | -91.9% | 273 | -98.5% | 0.02% | -92.4% |
| CNCE | Sell | CONCERT PHARMACEUTICALS INC | $236,000 | -95.8% | 15,858 | -95.8% | 0.02% | -96.1% |
| TTHI | Sell | TRANSITION THERAPEUTICS INC | $148,000 | -92.1% | 70,273 | -74.3% | 0.01% | -92.8% |
| ADHD | Exit | ALCOBRA LTD | $0 | – | -200 | -100.0% | 0.00% | – |
| SPPI | Exit | SPECTRUM PHARMACEUTICALS INC | $0 | – | -50,000 | -100.0% | -0.03% | – |
| BLRX | Exit | BIOLINERX LTDsponsored adr | $0 | – | -193,284 | -100.0% | -0.04% | – |
| OHRP | Exit | OHR PHARMACEUTICAL INC | $0 | – | -187,500 | -100.0% | -0.05% | – |
| ACHN | Exit | ACHILLION PHARMACEUTICALS IN | $0 | – | -65,538 | -100.0% | -0.07% | – |
| MSTX | Exit | MAST THERAPEUTICS INC | $0 | – | -1,374,900 | -100.0% | -0.07% | – |
| EBIO | Exit | ELEVEN BIOTHERAPEUTICS INC | $0 | – | -87,110 | -100.0% | -0.08% | – |
| JUNO | Exit | JUNO THERAPEUTICS INC | $0 | – | -15,000 | -100.0% | -0.10% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -157,179 | -100.0% | -0.11% | – |
| SGNT | Exit | SAGENT PHARMACEUTICALS INC | $0 | – | -50,000 | -100.0% | -0.12% | – |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -79,900 | -100.0% | -0.12% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -80,957 | -100.0% | -0.12% | – |
| ASND | Exit | ASCENDIS PHARMA A Ssponsored adr | $0 | – | -70,000 | -100.0% | -0.13% | – |
| ASMB | Exit | ASSEMBLY BIOSCIENCES INC | $0 | – | -100,000 | -100.0% | -0.14% | – |
| NLNK | Exit | NEWLINK GENETICS CORP | $0 | – | -25,000 | -100.0% | -0.14% | – |
| MDGN | Exit | MEDGENICS INC | $0 | – | -175,000 | -100.0% | -0.15% | – |
| OCRX | Exit | OCERA THERAPEUTICS INC | $0 | – | -321,254 | -100.0% | -0.16% | – |
| Exit | MANNKIND CORPput | $0 | – | -3,000 | -100.0% | -0.16% | – | |
| CNAT | Exit | CONATUS PHARMACEUTICALS INC | $0 | – | -220,000 | -100.0% | -0.16% | – |
| TKAI | Exit | TOKAI PHARMACEUTICALS INC | $0 | – | -146,341 | -100.0% | -0.17% | – |
| CLLS | Exit | CELLECTIS S Asponsored ads | $0 | – | -50,000 | -100.0% | -0.18% | – |
| THRM | Exit | GENTHERM INC | $0 | – | -34,550 | -100.0% | -0.18% | – |
| UNP | Exit | UNION PAC CORP | $0 | – | -17,489 | -100.0% | -0.20% | – |
| SRCL | Exit | STERICYCLE INC | $0 | – | -14,500 | -100.0% | -0.21% | – |
| PCLN | Exit | PRICELINE GRP INC | $0 | – | -1,820 | -100.0% | -0.22% | – |
| ITB | Exit | ISHARESus home cons etf | $0 | – | -76,000 | -100.0% | -0.22% | – |
| SGMO | Exit | SANGAMO BIOSCIENCES INC | $0 | – | -140,000 | -100.0% | -0.23% | – |
| AAVL | Exit | AVALANCHE BIOTECHNOLOGIES IN | $0 | – | -60,000 | -100.0% | -0.25% | – |
| ATRA | Exit | ATARA BIOTHERAPEUTICS INC | $0 | – | -63,579 | -100.0% | -0.28% | – |
| RTRX | Exit | RETROPHIN INC | $0 | – | -111,392 | -100.0% | -0.28% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -150,000 | -100.0% | -0.29% | – |
| AERI | Exit | AERIE PHARMACEUTICALS INC | $0 | – | -90,000 | -100.0% | -0.29% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -105,000 | -100.0% | -0.30% | – |
| KERX | Exit | KERYX BIOPHARMACEUTICALS INC | $0 | – | -230,000 | -100.0% | -0.30% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -75,000 | -100.0% | -0.31% | – |
| AEGR | Exit | AEGERION PHARMACEUTICALS INC | $0 | – | -120,000 | -100.0% | -0.33% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -13,796 | -100.0% | -0.34% | – |
| TJX | Exit | TJX COS INC NEW | $0 | – | -47,330 | -100.0% | -0.34% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC NE | $0 | – | -36,000 | -100.0% | -0.35% | – |
| Exit | DYAX CORPput | $0 | – | -2,000 | -100.0% | -0.35% | – | |
| ARIA | Exit | ARIAD PHARMACEUTICALS INC | $0 | – | -445,000 | -100.0% | -0.38% | – |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -25,000 | -100.0% | -0.45% | – |
| XLV | Exit | SELECT SECTOR SPDR TRsbi healthcare | $0 | – | -59,853 | -100.0% | -0.45% | – |
| CVS | Exit | CVS HEALTH CORP | $0 | – | -42,260 | -100.0% | -0.45% | – |
| KYTH | Exit | KYTHERA BIOPHARMACEUTICALS I | $0 | – | -90,000 | -100.0% | -0.47% | – |
| KMDA | Exit | KAMADA LTD | $0 | – | -293,727 | -100.0% | -0.54% | – |
| INSYQ | Exit | INSYS THERAPEUTICS INC NEW | $0 | – | -100,000 | -100.0% | -0.60% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -86,637 | -100.0% | -0.62% | – |
| DYAX | Exit | DYAX CORP | $0 | – | -367,556 | -100.0% | -0.64% | – |
| IWM | Exit | ISHARES TRrussell 2000 etf | $0 | – | -56,100 | -100.0% | -0.73% | – |
| ASPX | Exit | AUSPEX PHARMACEUTICALS INC | $0 | – | -125,074 | -100.0% | -1.31% | – |
| ENDP | Exit | ENDO INTL PLC | $0 | – | -210,000 | -100.0% | -1.96% | – |
| B108PS | Exit | ACTAVIS PLC | $0 | – | -192,100 | -100.0% | -5.95% | – |
| Exit | SPDR S&P 500 ETF TRput | $0 | – | -3,500 | -100.0% | -7.52% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2015-08-06
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.