$4.83 Billion is the total value of RTW INVESTMENTS, LP's 106 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 40.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $274,876,000 | -18.0% | 1,683,362 | -14.8% | 5.69% | +16.3% |
| TMO | Sell | THERMO FISHER SCIENTIFIC INC | $220,312,000 | -24.2% | 373,000 | -14.4% | 4.56% | +7.5% |
| PTCT | Sell | PTC THERAPEUTICS INC | $194,804,000 | -7.6% | 5,221,228 | -1.4% | 4.03% | +31.0% |
| VCEL | Sell | VERICEL CORP | $153,552,000 | -13.5% | 4,017,570 | -11.1% | 3.18% | +22.6% |
| TNDM | Sell | TANDEM DIABETES CARE INC | $116,864,000 | -33.1% | 1,004,936 | -13.4% | 2.42% | -5.2% |
| AXNX | Sell | AXONICS INC | $109,166,000 | +0.3% | 1,743,864 | -10.3% | 2.26% | +42.1% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEW | $105,048,000 | -30.7% | 3,084,215 | -21.4% | 2.17% | -1.8% |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INC | $104,140,000 | -19.3% | 2,757,947 | -15.5% | 2.16% | +14.3% |
| FULC | Sell | FULCRUM THERAPEUTICS INC | $85,405,000 | +24.9% | 3,611,194 | -6.6% | 1.77% | +77.0% |
| ACET | Sell | ADICET BIO INC | $59,700,000 | +12.9% | 2,989,482 | -1.1% | 1.24% | +60.1% |
| GH | Sell | GUARDANT HEALTH INC | $45,698,000 | -43.8% | 689,887 | -15.2% | 0.95% | -20.4% |
| CSTL | Sell | CASTLE BIOSCIENCES INC | $22,281,000 | -13.2% | 496,675 | -17.1% | 0.46% | +22.9% |
| LUNG | Sell | PULMONX CORP | $19,805,000 | -47.0% | 798,255 | -31.5% | 0.41% | -24.8% |
| ITOS | Sell | ITEOS THERAPEUTICS INC | $15,736,000 | -85.6% | 489,014 | -79.2% | 0.33% | -79.6% |
| CTMX | Sell | CYTOMX THERAPEUTICS INC | $15,432,000 | -40.9% | 5,779,700 | -4.1% | 0.32% | -16.3% |
| NSTG | Sell | NANOSTRING TECHNOLOGIES INC | $14,040,000 | -45.0% | 404,029 | -33.1% | 0.29% | -21.8% |
| TELA | Sell | TELA BIO INC | $11,834,000 | -33.9% | 1,017,546 | -27.3% | 0.24% | -6.5% |
| Sell | SIGHT SCIENCES INC | $11,526,000 | -44.6% | 997,099 | -15.8% | 0.24% | -21.4% | |
| LJPC | Sell | LA JOLLA PHARMACEUTICAL CO | $9,938,000 | -8.2% | 2,327,403 | -0.0% | 0.21% | +30.4% |
| AGEN | Sell | AGENUS INC | $8,813,000 | -53.4% | 3,582,481 | -39.0% | 0.18% | -34.1% |
| PRQR | Sell | PROQR THRAPEUTICS N V | $6,354,000 | -88.7% | 7,019,610 | -0.1% | 0.13% | -83.9% |
| Sell | PROCEPT BIOROBOTICS CORP | $5,638,000 | +16.1% | 161,138 | -17.0% | 0.12% | +64.8% | |
| JNJ | Sell | JOHNSON & JOHNSON | $3,213,000 | -85.0% | 18,127 | -85.5% | 0.07% | -78.9% |
| APLS | Sell | APELLIS PHARMACEUTICALS INC | $2,601,000 | -97.2% | 51,194 | -97.4% | 0.05% | -96.1% |
| GTH | Sell | GENETRON HLDGS LTDads | $2,626,000 | -69.7% | 1,198,961 | -15.7% | 0.05% | -57.5% |
| Sell | SOPHIA GENETICS SAordinary shares | $1,752,000 | -58.6% | 226,589 | -24.5% | 0.04% | -41.9% | |
| Sell | MAXCYTE INC | $1,395,000 | -50.2% | 199,567 | -27.4% | 0.03% | -29.3% | |
| CNTB | Sell | CONNECT BIOPHARMA HLDGS LTDads | $1,349,000 | -41.8% | 446,564 | -0.8% | 0.03% | -17.6% |
| AKYA | Sell | AKOYA BIOSCIENCES INC | $854,000 | -44.2% | 77,676 | -22.3% | 0.02% | -18.2% |
| ADVM | Sell | ADVERUM BIOTECHNOLOGIES INC | $293,000 | -97.8% | 223,725 | -97.0% | 0.01% | -96.9% |
| ACHL | Exit | ACHILLES THERAPEUTICS PLCsponsored ads | $0 | – | -12,229 | -100.0% | -0.00% | – |
| BOLT | Exit | BOLT BIOTHERAPEUTICS INC | $0 | – | -126,365 | -100.0% | -0.01% | – |
| MDXG | Exit | MIMEDX GROUP INC | $0 | – | -295,748 | -100.0% | -0.03% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -400,000 | -100.0% | -0.03% | – | |
| Exit | MINK THERAPEUTICS INC | $0 | – | -416,666 | -100.0% | -0.03% | – | |
| Exit | TANGO THERAPEUTICS INC | $0 | – | -180,819 | -100.0% | -0.03% | – | |
| BMEA | Exit | BIOMEA FUSION INC | $0 | – | -593,846 | -100.0% | -0.06% | – |
| MRUS | Exit | MERUS N V | $0 | – | -196,231 | -100.0% | -0.09% | – |
| VINC | Exit | VINCERX PHARMA INC | $0 | – | -741,236 | -100.0% | -0.11% | – |
| ABUS | Exit | ARBUTUS BIOPHARMA CORP | $0 | – | -2,504,493 | -100.0% | -0.14% | – |
| OSUR | Exit | ORASURE TECHNOLOGIES INC | $0 | – | -1,154,380 | -100.0% | -0.15% | – |
| CLSD | Exit | CLEARSIDE BIOMEDICAL INC | $0 | – | -3,806,018 | -100.0% | -0.15% | – |
| NEO | Exit | NEOGENOMICS INC | $0 | – | -311,111 | -100.0% | -0.16% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -666,666 | -100.0% | -0.32% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -346,842 | -100.0% | -0.34% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -5,968,017 | -100.0% | -0.70% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -582,265 | -100.0% | -0.77% | – |
| IDYA | Exit | IDEAYA BIOSCIENCES INC | $0 | – | -2,520,076 | -100.0% | -0.87% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -6,722,624 | -100.0% | -1.64% | – |
| SPY | Exit | SPDR S&P 500 ETF TRtr unit | $0 | – | -889,739 | -100.0% | -6.17% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.