$1.66 Billion is the total value of Palo Alto Investors LP's 42 reported holdings in Q3 2021. The portfolio turnover from Q2 2021 to Q3 2021 was 4.8% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ABMD | Sell | ABIOMED INC | $178,977,000 | -1.8% | 549,820 | -5.8% | 10.80% | +7.5% |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $171,039,000 | -7.4% | 2,212,950 | 0.0% | 10.32% | +1.4% | |
| INSM | INSMED INC | $165,766,000 | -3.2% | 6,019,106 | 0.0% | 10.00% | +6.0% | |
| STAA | Sell | STAAR SURGICAL CO | $146,590,000 | -24.2% | 1,140,511 | -10.0% | 8.85% | -17.0% |
| UTHR | UNITED THERAPEUTICS CORP | $126,844,000 | +2.9% | 687,206 | 0.0% | 7.66% | +12.7% | |
| PRTA | Sell | PROTHENA CORP PLC | $120,043,000 | +34.9% | 1,685,282 | -2.7% | 7.24% | +47.7% |
| BIIB | BIOGEN INC | $102,329,000 | -18.3% | 361,600 | 0.0% | 6.18% | -10.5% | |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $96,589,000 | +0.2% | 10,114,043 | +1.1% | 5.83% | +9.7% |
| RVNC | REVANCE THERAPEUTICS INC | $89,204,000 | -6.0% | 3,201,866 | 0.0% | 5.38% | +2.9% | |
| VNDA | VANDA PHARMACEUTICALS INC | $64,992,000 | -20.3% | 3,791,805 | 0.0% | 3.92% | -12.7% | |
| EHTH | EHEALTH INC | $46,408,000 | -30.7% | 1,145,870 | 0.0% | 2.80% | -24.1% | |
| ACAD | ACADIA PHARMACEUTICALS INC | $38,832,000 | -31.9% | 2,337,877 | 0.0% | 2.34% | -25.4% | |
| ALGN | ALIGN TECHNOLOGY INC | $36,868,000 | +8.9% | 55,405 | 0.0% | 2.22% | +19.2% | |
| EPZM | EPIZYME INC | $35,105,000 | -38.4% | 6,856,513 | 0.0% | 2.12% | -32.5% | |
| KPTI | KARYOPHARM THERAPEUTICS INC | $31,329,000 | -43.6% | 5,383,052 | 0.0% | 1.89% | -38.2% | |
| SAGE | Buy | SAGE THERAPEUTICS INC | $27,380,000 | -19.7% | 617,930 | +2.9% | 1.65% | -12.1% |
| GRTS | GRITSTONE ONCOLOGY INC | $25,448,000 | +18.3% | 2,356,282 | 0.0% | 1.54% | +29.5% | |
| GOSS | GOSSAMER BIO INC | $22,286,000 | +54.8% | 1,772,950 | 0.0% | 1.34% | +69.6% | |
| CLVS | CLOVIS ONCOLOGY INC | $20,000,000 | -23.1% | 4,484,411 | 0.0% | 1.21% | -15.8% | |
| ALKS | Buy | ALKERMES PLC | $18,193,000 | +52.3% | 589,900 | +21.1% | 1.10% | +66.9% |
| DRNA | Buy | DICERNA PHARMACEUTICALS INC | $17,251,000 | +38.9% | 855,713 | +157.2% | 1.04% | +52.2% |
| AZN | New | ASTRAZENECA PLC-SPONS ADRsponsored adr | $12,101,000 | – | 201,489 | +100.0% | 0.73% | – |
| ANAB | ANAPTYSBIO INC | $11,840,000 | +4.6% | 436,592 | 0.0% | 0.72% | +14.6% | |
| PBYI | PUMA BIOTECHNOLOGY INC | $9,765,000 | -23.6% | 1,392,997 | 0.0% | 0.59% | -16.5% | |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $8,502,000 | +23.4% | 444,900 | +10.9% | 0.51% | +35.0% |
| KZR | KEZAR LIFE SCIENCES INC | $5,670,000 | +59.1% | 656,200 | 0.0% | 0.34% | +74.5% | |
| CYTK | CYTOKINETICS INC | $4,421,000 | +80.6% | 123,686 | 0.0% | 0.27% | +97.8% | |
| KLDO | KALEIDO BIOSCIENCES INC | $4,294,000 | -26.6% | 786,400 | 0.0% | 0.26% | -19.6% | |
| TVTX | TRAVERE THERAPEUTICS INC | $4,027,000 | +66.2% | 166,069 | 0.0% | 0.24% | +81.3% | |
| ZGNX | ZOGENIX INC | $3,261,000 | -12.1% | 214,700 | 0.0% | 0.20% | -3.4% | |
| MGTA | MAGENTA THERAPEUTICS INC | $3,147,000 | -25.6% | 432,300 | 0.0% | 0.19% | -18.5% | |
| RIGL | RIGEL PHARMACEUTICALS INC | $2,368,000 | -16.4% | 652,395 | 0.0% | 0.14% | -8.3% | |
| ALDX | ALDEYRA THERAPEUTICS INC | $1,412,000 | -22.5% | 160,800 | 0.0% | 0.08% | -15.0% | |
| TCMD | TACTILE SYSTEMS TECHNOLOGY I | $1,205,000 | -14.5% | 27,100 | 0.0% | 0.07% | -6.4% | |
| ATNX | ATHENEX INC | $958,000 | -34.8% | 318,200 | 0.0% | 0.06% | -28.4% | |
| ALIMERA SCIENCES INC | $848,000 | -53.6% | 200,919 | 0.0% | 0.05% | -49.5% | ||
| URGN | UROGEN PHARMA LTD | $412,000 | +10.2% | 24,500 | 0.0% | 0.02% | +19.0% | |
| SYRS | SYROS PHARMACEUTICALS INC | $360,000 | -18.0% | 80,600 | 0.0% | 0.02% | -8.3% | |
| MARINUS PHARMACEUTICALS INC | $357,000 | -36.5% | 31,330 | 0.0% | 0.02% | -29.0% | ||
| VIRX | VIRACTA THERAPEUTICS INC | $266,000 | -29.4% | 33,212 | 0.0% | 0.02% | -23.8% | |
| IDRA | IDERA PHARMACEUTICALS INC | $79,000 | -14.1% | 77,044 | 0.0% | 0.01% | 0.0% | |
| NERV | MINERVA NEUROSCIENCES INC | $63,000 | -25.0% | 36,319 | 0.0% | 0.00% | -20.0% | |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -94,850 | -100.0% | -0.96% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-11-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Biomarin Pharmaceuticals, Inc | 42 | Q3 2023 | 16.6% |
| UNITED THERAPEUTICS CORP DEL | 42 | Q3 2023 | 15.3% |
| INSMED INC | 42 | Q3 2023 | 14.1% |
| STAAR Surgical Company | 42 | Q3 2023 | 11.8% |
| AMICUS THERAPEUTICS INC | 42 | Q3 2023 | 12.1% |
| VANDA PHARMACEUTICALS INC | 42 | Q3 2023 | 5.8% |
| PROTHENA CORP PLC | 42 | Q3 2023 | 9.1% |
| CYTOKINETICS INC | 40 | Q3 2023 | 0.4% |
| ALIGN TECHNOLOGY INC | 39 | Q3 2023 | 2.5% |
| ABIOMED INC | 38 | Q3 2022 | 17.1% |
View Palo Alto Investors LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ALIMERA SCIENCES INCSold out | April 03, 2023 | 0 | 0.0% |
| Epizyme, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| INSMED Inc | February 14, 2023 | 5,871,291 | 4.3% |
| Vanda Pharmaceuticals Inc. | February 14, 2023 | 1,087,064 | 1.4% |
| ALIMERA SCIENCES INC | February 14, 2022 | 802,423 | 11.6% |
| Clovis Oncology, Inc. | February 14, 2022 | 3,997,826 | 3.1% |
| STAAR SURGICAL CO | February 14, 2022 | 1,140,511 | 2.4% |
| Aimmune Therapeutics, Inc.Sold out | February 16, 2021 | 0 | 0.0% |
| AMAG PHARMACEUTICALS, INC.Sold out | February 16, 2021 | 0 | 0.0% |
| ALIMERA SCIENCES INC | February 14, 2020 | 802,424 | 16.2% |
View Palo Alto Investors LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| SC 13G/A | 2023-04-03 |
| 4 | 2023-03-28 |
View Palo Alto Investors LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.