$2.21 Billion is the total value of Tekla Capital Management LLC's 217 reported holdings in Q1 2020. The portfolio turnover from Q4 2019 to Q1 2020 was 11.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GILD | Sell | Gilead Sciences, Inc. | $141,170,000 | +14.9% | 1,888,305 | -0.1% | 6.38% | +37.4% |
| AMGN | Sell | Amgen Inc. | $121,612,000 | -18.3% | 599,871 | -2.8% | 5.50% | -2.3% |
| VRTX | Sell | Vertex Pharmaceuticals Incorporated | $115,579,000 | +6.9% | 485,730 | -1.6% | 5.22% | +27.8% |
| JNJ | Sell | Johnson & Johnson | $109,988,000 | -17.8% | 838,769 | -8.5% | 4.97% | -1.7% |
| BIIB | Buy | Biogen Inc. | $105,271,000 | +24.4% | 332,735 | +16.7% | 4.76% | +48.7% |
| REGN | Sell | Regeneron Pharmaceuticals, Inc. | $83,438,000 | +10.4% | 170,878 | -15.1% | 3.77% | +32.0% |
| MRK | Sell | Merck & Co., Inc. | $78,679,000 | -28.6% | 1,022,596 | -15.6% | 3.56% | -14.6% |
| ILMN | Sell | Illumina, Inc. | $72,464,000 | -19.9% | 265,319 | -2.7% | 3.28% | -4.2% |
| PFE | Sell | Pfizer Inc. | $59,413,000 | -27.3% | 1,820,248 | -12.7% | 2.69% | -13.1% |
| UNH | Sell | Unitedhealth Group Incorporated | $56,566,000 | -22.7% | 226,827 | -8.8% | 2.56% | -7.6% |
| BMY | Buy | Bristol-Myers Squibb Company | $47,097,000 | -5.3% | 844,932 | +9.0% | 2.13% | +13.2% |
| MDT | Sell | Medtronic plcshares | $40,311,000 | -24.5% | 447,011 | -5.1% | 1.82% | -9.8% |
| ALXN | Sell | Alexion Pharmaceuticals, Inc. | $37,113,000 | -21.3% | 413,326 | -5.2% | 1.68% | -5.9% |
| ABT | Sell | Abbott Laboratories | $36,815,000 | -10.2% | 466,550 | -1.1% | 1.66% | +7.4% |
| LLY | Buy | Eli Lilly and Company | $35,883,000 | +29.9% | 258,669 | +23.1% | 1.62% | +55.2% |
| TMO | Sell | Thermo Fisher Scientific Inc. | $31,770,000 | -20.8% | 112,025 | -9.2% | 1.44% | -5.3% |
| INCY | Buy | Incyte Corporation | $31,653,000 | -5.4% | 432,246 | +12.8% | 1.43% | +13.0% |
| CVS | CVS Health Corporation | $29,546,000 | -20.1% | 497,986 | 0.0% | 1.34% | -4.5% | |
| AGN | Sell | Allergan plcshares | $27,978,000 | -8.3% | 157,981 | -1.0% | 1.26% | +9.6% |
| ABBV | AbbVie Inc. | $25,974,000 | -14.0% | 340,916 | 0.0% | 1.17% | +2.8% | |
| CI | Sell | Cigna Corporation | $25,276,000 | -35.1% | 142,655 | -25.1% | 1.14% | -22.5% |
| SGEN | Sell | Seattle Genetics, Inc. | $24,752,000 | -21.7% | 214,530 | -22.5% | 1.12% | -6.4% |
| BMRN | Sell | BioMarin Pharmaceutical Inc. | $22,867,000 | -2.2% | 270,613 | -2.2% | 1.03% | +17.0% |
| SYK | Buy | Stryker Corporation | $22,609,000 | -5.3% | 135,795 | +19.5% | 1.02% | +13.3% |
| DHR | Sell | Danaher Corporation | $22,056,000 | -13.2% | 159,352 | -3.7% | 1.00% | +3.9% |
| BSX | Buy | Boston Scientific Corporation | $19,175,000 | -24.9% | 587,662 | +4.1% | 0.87% | -10.2% |
| BDX | Buy | Becton, Dickinson and Company | $17,866,000 | -0.9% | 77,754 | +17.4% | 0.81% | +18.6% |
| ZTS | Sell | Zoetis Inc.class a | $17,883,000 | -29.0% | 151,952 | -20.2% | 0.81% | -15.2% |
| NBIX | Buy | Neurocrine Biosciences, Inc. | $17,842,000 | -14.0% | 206,150 | +6.8% | 0.81% | +2.8% |
| CNC | Buy | Centene Corporation | $17,122,000 | +82.1% | 288,194 | +92.7% | 0.77% | +117.4% |
| ISRG | Sell | Intuitive Surgical, Inc. | $16,856,000 | -26.3% | 34,039 | -12.0% | 0.76% | -11.9% |
| MYL | Sell | Mylan N.V.shares | $15,070,000 | -27.8% | 1,010,754 | -2.7% | 0.68% | -13.7% |
| ALNY | Sell | Alnylam Pharmaceuticals, Inc. | $14,980,000 | -9.5% | 137,617 | -4.3% | 0.68% | +8.1% |
| ANTM | Sell | Anthem, Inc. | $14,887,000 | -51.7% | 65,568 | -35.7% | 0.67% | -42.2% |
| NVS | Sell | Novartis AGsponsored adr | $14,828,000 | -25.8% | 179,847 | -14.8% | 0.67% | -11.4% |
| HUM | Sell | Humana Inc. | $14,486,000 | -28.2% | 46,130 | -16.1% | 0.66% | -14.2% |
| SNY | Buy | Sanofisponsored adr | $14,312,000 | +52.8% | 327,367 | +75.4% | 0.65% | +82.8% |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $13,707,000 | -41.5% | 140,129 | -22.8% | 0.62% | -30.0% |
| EW | Sell | Edwards Lifesciences Corporation | $12,710,000 | -21.7% | 67,382 | -3.1% | 0.58% | -6.4% |
| AZN | AstraZeneca PLCsponsored adr | $12,331,000 | -10.4% | 276,098 | 0.0% | 0.56% | +6.9% | |
| PRAH | Sell | PRA Health Sciences, Inc. | $11,917,000 | -29.9% | 143,508 | -6.2% | 0.54% | -16.2% |
| HZNP | Buy | Horizon Therapeutics plcshares | $11,826,000 | +7.2% | 399,257 | +31.0% | 0.54% | +28.3% |
| TECH | Buy | Bio-Techne Corporation | $10,939,000 | -0.5% | 57,691 | +15.2% | 0.50% | +19.0% |
| IDXX | Sell | IDEXX Laboratories, Inc. | $9,766,000 | -14.3% | 40,314 | -7.6% | 0.44% | +2.3% |
| ACAD | Buy | ACADIA Pharmaceuticals Inc. | $9,363,000 | +0.3% | 221,599 | +1.5% | 0.42% | +19.8% |
| WELL | Buy | Welltower Inc. | $9,297,000 | -40.7% | 203,083 | +6.0% | 0.42% | -29.2% |
| BGNE | Sell | BeiGene, Ltd.sponsored adr | $9,231,000 | -31.3% | 74,984 | -7.5% | 0.42% | -17.9% |
| IONS | Sell | Ionis Pharmaceuticals, Inc. | $9,135,000 | -28.0% | 193,201 | -8.0% | 0.41% | -14.0% |
| EXEL | Exelixis, Inc. | $8,870,000 | -2.3% | 515,125 | 0.0% | 0.40% | +16.9% | |
| IQV | Buy | IQVIA Holdings Inc. | $8,873,000 | +60.3% | 82,266 | +129.7% | 0.40% | +91.9% |
| OHI | Buy | Omega Healthcare Investors, Inc. | $8,133,000 | -32.6% | 306,433 | +7.6% | 0.37% | -19.3% |
| BPMC | Buy | Blueprint Medicines Corporation | $8,148,000 | -13.0% | 139,336 | +19.2% | 0.37% | +4.0% |
| NVO | Sell | Novo Nordisk A/Ssponsored adr | $8,067,000 | -37.0% | 134,005 | -39.5% | 0.36% | -24.7% |
| MCK | Sell | McKesson Corporation | $8,051,000 | -13.5% | 59,525 | -11.6% | 0.36% | +3.4% |
| BAX | Sell | Baxter International Inc. | $7,890,000 | -27.4% | 97,183 | -25.2% | 0.36% | -13.1% |
| ZBH | Buy | Zimmer Biomet Holdings, Inc. | $7,901,000 | -17.1% | 78,168 | +22.8% | 0.36% | -0.8% |
| GSK | Sell | GlaxoSmithKline PLCshares | $7,838,000 | -35.1% | 206,868 | -19.5% | 0.35% | -22.5% |
| ASND | Ascendis Pharma A/Ssponsored adr | $7,807,000 | -19.1% | 69,332 | 0.0% | 0.35% | -3.3% | |
| MRNA | New | Moderna, Inc. | $7,612,000 | – | 254,146 | +100.0% | 0.34% | – |
| HCA | Sell | HCA Healthcare, Inc. | $7,532,000 | -46.8% | 83,833 | -12.5% | 0.34% | -36.6% |
| NVCR | NovoCure Ltd.ordinary shares | $7,235,000 | -20.1% | 107,438 | 0.0% | 0.33% | -4.4% | |
| MPW | Buy | Medical Properties Trust, Inc. | $7,119,000 | -9.9% | 411,743 | +10.0% | 0.32% | +7.7% |
| TEVA | Teva Pharmaceutical Industries Ltd.sponsored adr | $7,057,000 | -8.4% | 785,851 | 0.0% | 0.32% | +9.6% | |
| DOC | Buy | Physicians Realty Trust | $6,911,000 | -20.1% | 495,733 | +8.5% | 0.31% | -4.6% |
| FGEN | FibroGen, Inc. | $6,751,000 | -19.0% | 194,270 | 0.0% | 0.30% | -3.2% | |
| JAZZ | Sell | Jazz Pharmaceuticals plcshares | $6,728,000 | -47.4% | 67,456 | -21.3% | 0.30% | -37.2% |
| AGIO | Sell | Agios Pharmaceuticals, Inc. | $6,633,000 | -35.8% | 186,964 | -13.6% | 0.30% | -23.3% |
| IOVA | Sell | Iovance Biotherapeutics, Inc. | $6,618,000 | -1.8% | 221,073 | -9.2% | 0.30% | +17.3% |
| IMMU | Immunomedics, Inc. | $6,566,000 | -36.3% | 487,103 | 0.0% | 0.30% | -23.8% | |
| STRO | Sutro Biopharma, Inc. | $6,541,000 | -7.3% | 641,268 | 0.0% | 0.30% | +10.9% | |
| MRTX | Buy | Mirati Therapeutics, Inc. | $6,056,000 | -33.7% | 78,784 | +11.2% | 0.27% | -20.6% |
| GBT | Sell | Global Blood Therapeutics, Inc. | $6,033,000 | -48.4% | 118,083 | -19.8% | 0.27% | -38.2% |
| UTHR | Buy | United Therapeutics Corporationclass b | $6,023,000 | +26.4% | 63,513 | +17.4% | 0.27% | +51.1% |
| ARGX | argenx SEsponsored adr | $5,925,000 | -17.9% | 44,977 | 0.0% | 0.27% | -1.8% | |
| BCEL | Sell | Atreca, Inc. | $5,833,000 | -28.2% | 352,424 | -32.9% | 0.26% | -14.0% |
| LTC | Buy | LTC Properties, Inc. | $5,633,000 | -24.1% | 182,293 | +10.0% | 0.26% | -9.3% |
| BMYRT | Bristol-Myers Squibb Companyright | $5,600,000 | +26.2% | 1,473,710 | 0.0% | 0.25% | +50.6% | |
| SBRA | Buy | Sabra Health Care REIT, Inc. | $5,576,000 | -44.0% | 510,660 | +9.5% | 0.25% | -33.0% |
| VTR | Buy | Ventas, Inc. | $5,577,000 | -49.5% | 208,108 | +8.7% | 0.25% | -39.7% |
| PTCT | Buy | PTC Therapeutics, Inc. | $5,390,000 | +13.0% | 120,827 | +21.6% | 0.24% | +35.6% |
| ZGNX | Buy | Zogenix, Inc. | $5,327,000 | -5.1% | 215,406 | +100.0% | 0.24% | +13.7% |
| TBPH | Buy | Theravance Biopharma, Inc. | $5,288,000 | +73.5% | 228,836 | +94.4% | 0.24% | +107.8% |
| CERN | New | Cerner Corporation | $5,134,000 | – | 81,500 | +100.0% | 0.23% | – |
| RETA | Buy | Reata Pharmaceuticals, Inc.class a | $5,071,000 | -6.1% | 35,129 | +33.0% | 0.23% | +12.3% |
| TFX | Buy | Teleflex Incorporated | $5,052,000 | -14.0% | 17,252 | +10.5% | 0.23% | +2.7% |
| ABC | Sell | AmerisourceBergen Corporation | $4,788,000 | -51.3% | 54,107 | -53.2% | 0.22% | -41.9% |
| ALLO | Buy | Allogene Therapeutics, Inc. | $4,748,000 | +127.6% | 244,261 | +204.3% | 0.22% | +172.2% |
| WAT | New | Waters Corporation | $4,733,000 | – | 26,000 | +100.0% | 0.21% | – |
| NKTR | Sell | Nektar Therapeutics | $4,696,000 | -23.3% | 263,079 | -7.3% | 0.21% | -8.6% |
| APLS | Buy | Apellis Pharmaceuticals, Inc. | $4,648,000 | +15.9% | 173,494 | +32.4% | 0.21% | +38.2% |
| AVDL | Sell | Avadel Pharmaceuticals plcsponsored adr | $4,495,000 | -26.9% | 566,066 | -30.5% | 0.20% | -12.9% |
| XRAY | Sell | DENTSPLY SIRONA Inc. | $4,455,000 | -34.3% | 114,736 | -4.2% | 0.20% | -21.5% |
| XNCR | Xencor, Inc. | $4,429,000 | -13.1% | 148,231 | 0.0% | 0.20% | +3.6% | |
| GWPH | GW Pharmaceuticals plcads | $4,387,000 | -16.3% | 50,101 | 0.0% | 0.20% | 0.0% | |
| RARE | Ultragenyx Pharmaceutical Inc. | $4,331,000 | +4.0% | 97,480 | 0.0% | 0.20% | +24.8% | |
| ABMD | Sell | ABIOMED, Inc. | $4,285,000 | -23.2% | 29,516 | -9.8% | 0.19% | -8.1% |
| SYNH | Sell | Syneos Health, Inc.class a | $4,257,000 | -38.2% | 108,001 | -6.8% | 0.19% | -26.4% |
| MTD | Buy | Mettler-Toledo International Inc. | $4,228,000 | +26.2% | 6,123 | +45.0% | 0.19% | +50.4% |
| LH | Laboratory Corporation of America Holdingssponsored adr | $3,972,000 | -25.3% | 31,424 | 0.0% | 0.18% | -10.4% | |
| GRTX | Galera Therapeutics, Inc. | $3,958,000 | -27.8% | 416,666 | 0.0% | 0.18% | -13.5% | |
| BLUE | Sell | bluebird bio, Inc. | $3,870,000 | -53.9% | 84,194 | -12.0% | 0.18% | -45.0% |
| A | Buy | Agilent Technologies, Inc. | $3,762,000 | +61.4% | 52,525 | +92.2% | 0.17% | +93.2% |
| FATE | Fate Therapeutics, Inc. | $3,680,000 | +13.5% | 165,672 | 0.0% | 0.17% | +35.0% | |
| XLRN | Sell | Acceleron Pharma Inc. | $3,649,000 | -20.3% | 40,606 | -53.0% | 0.16% | -4.6% |
| PEAK | Buy | Healthpeak Properties, Inc. | $3,587,000 | -19.0% | 150,392 | +17.0% | 0.16% | -3.6% |
| SNN | Smith & Nephew plcshares | $3,571,000 | -25.4% | 99,560 | 0.0% | 0.16% | -11.0% | |
| ARDX | Ardelyx, Inc. | $3,455,000 | -24.2% | 607,698 | 0.0% | 0.16% | -9.3% | |
| FOLD | Amicus Therapeutics, Inc. | $3,409,000 | -5.1% | 368,960 | 0.0% | 0.15% | +13.2% | |
| PIRS | Pieris Pharmaceuticals, Inc. | $3,304,000 | -37.0% | 1,449,269 | 0.0% | 0.15% | -24.7% | |
| EPZM | Sell | Epizyme, Inc. | $3,222,000 | -62.9% | 207,752 | -41.2% | 0.15% | -55.5% |
| CRSP | CRISPR Therapeutics AGnamen akt | $3,233,000 | -30.4% | 76,222 | 0.0% | 0.15% | -17.0% | |
| TAK | Takeda Pharmaceutical Company Ltd.sponsored ads | $3,190,000 | -23.1% | 210,146 | 0.0% | 0.14% | -8.3% | |
| GMAB | Buy | Genmab A/Ssponsored ads | $3,139,000 | +750.7% | 148,148 | +796.8% | 0.14% | +914.3% |
| RCKT | Rocket Pharmaceuticals, Inc. | $2,895,000 | -38.7% | 207,555 | 0.0% | 0.13% | -26.8% | |
| HR | Buy | Healthcare Realty Trust Incorporated | $2,905,000 | +4.1% | 104,024 | +24.4% | 0.13% | +23.6% |
| PKI | Buy | PerkinElmer, Inc. | $2,898,000 | +57.0% | 38,494 | +102.5% | 0.13% | +87.1% |
| ALLK | Sell | Allakos Inc. | $2,865,000 | -57.9% | 64,397 | -9.8% | 0.13% | -49.4% |
| SAGE | Sage Therapeutics Inc | $2,763,000 | -60.2% | 96,211 | 0.0% | 0.12% | -52.5% | |
| INGN | Inogen, Inc. | $2,656,000 | -24.4% | 51,406 | 0.0% | 0.12% | -9.8% | |
| RMD | Sell | ResMed Inc. | $2,626,000 | -39.0% | 17,831 | -35.8% | 0.12% | -27.0% |
| EDIT | Sell | Editas Medicine, Inc. | $2,582,000 | -41.1% | 130,201 | -12.0% | 0.12% | -29.5% |
| DCPH | Deciphera Pharmaceuticals, Inc. | $2,527,000 | -33.8% | 61,370 | 0.0% | 0.11% | -20.8% | |
| MNTA | New | Momenta Pharmaceuticals, Inc. | $2,484,000 | – | 91,316 | +100.0% | 0.11% | – |
| ALKS | Sell | Alkermes plcshares | $2,450,000 | -39.4% | 169,930 | -14.2% | 0.11% | -27.5% |
| AMRN | Buy | Amarin Corporation plcsponsored adr | $2,415,000 | -72.4% | 603,791 | +47.9% | 0.11% | -67.1% |
| ACHC | Sell | Acadia Healthcare Company, Inc. | $2,408,000 | -46.8% | 131,200 | -3.7% | 0.11% | -36.3% |
| CRL | Sell | Charles River Laboratories International, Inc. | $2,331,000 | -27.2% | 18,467 | -11.9% | 0.10% | -13.2% |
| LGND | Sell | Ligand Pharmaceuticals Incorporated | $2,225,000 | -47.9% | 30,590 | -25.3% | 0.10% | -37.7% |
| PHG | Buy | Koninklijke Philips N.V.ny reg sh | $2,241,000 | +7.5% | 55,796 | +30.7% | 0.10% | +27.8% |
| ICPT | Intercept Pharmaceuticals, Inc. | $2,167,000 | -49.2% | 34,414 | 0.0% | 0.10% | -39.1% | |
| ARWR | Sell | Arrowhead Pharmaceuticals, Inc. | $2,134,000 | -68.1% | 74,186 | -29.6% | 0.10% | -62.1% |
| QURE | Sell | uniQure N.V.shares | $2,081,000 | -59.2% | 43,849 | -38.4% | 0.09% | -51.3% |
| YMAB | Buy | Y-mAbs Therapeutics, Inc. | $1,998,000 | +464.4% | 76,548 | +575.9% | 0.09% | +592.3% |
| ENDP | Endo International plcshares | $1,967,000 | -21.1% | 531,570 | 0.0% | 0.09% | -5.3% | |
| ZLAB | Zai Lab Ltd.adr | $1,932,000 | +23.8% | 37,523 | 0.0% | 0.09% | +47.5% | |
| ALC | Sell | Alcon Inc.ordinary shares | $1,864,000 | -40.5% | 36,686 | -33.7% | 0.08% | -28.8% |
| AXSM | New | Axsome Therapeutics, Inc. | $1,858,000 | – | 31,591 | +100.0% | 0.08% | – |
| BHC | Sell | Bausch Health Companies Inc. | $1,835,000 | -55.8% | 118,412 | -14.7% | 0.08% | -47.1% |
| Buy | Trillium Therapeutics Inc. | $1,810,000 | +294.3% | 448,049 | +0.4% | 0.08% | +382.4% | |
| CHRS | Sell | Coherus Biosciences, Inc. | $1,811,000 | -19.6% | 111,663 | -10.8% | 0.08% | -3.5% |
| GMRE | Buy | Global Medical REIT Inc. | $1,770,000 | +13.3% | 174,897 | +48.1% | 0.08% | +35.6% |
| ALGN | Sell | Align Technology, Inc. | $1,747,000 | -72.0% | 10,041 | -55.1% | 0.08% | -66.5% |
| RARX | Sell | Ra Pharmaceuticals, Inc. | $1,716,000 | -34.5% | 35,743 | -36.0% | 0.08% | -21.2% |
| HTA | Buy | Healthcare Trust of America, Inc. | $1,716,000 | +23.2% | 70,662 | +53.6% | 0.08% | +47.2% |
| DGX | Quest Diagnostics Incorporated | $1,688,000 | -24.8% | 21,025 | 0.0% | 0.08% | -10.6% | |
| ANAB | AnaptysBio, Inc. | $1,671,000 | -13.1% | 118,261 | 0.0% | 0.08% | +4.1% | |
| GH | Buy | Guardant Health, Inc. | $1,646,000 | +385.5% | 23,656 | +445.9% | 0.07% | +469.2% |
| STE | Sell | STERIS plcshares | $1,570,000 | -30.3% | 11,218 | -24.2% | 0.07% | -16.5% |
| INSM | Sell | Insmed Incorporated | $1,577,000 | -59.9% | 98,387 | -40.3% | 0.07% | -52.3% |
| HRTX | Buy | Heron Therapeutics, Inc. | $1,540,000 | +9.5% | 131,183 | +119.2% | 0.07% | +32.1% |
| BHVN | Buy | Biohaven Pharmaceutical Holding Company Ltd. | $1,537,000 | -3.1% | 45,164 | +55.1% | 0.07% | +15.0% |
| PACB | Pacific Biosciences of California, Inc. | $1,516,000 | -40.5% | 495,495 | 0.0% | 0.07% | -28.1% | |
| ITCI | Intra-Cellular Therapies, Inc. | $1,448,000 | -55.2% | 94,238 | 0.0% | 0.06% | -46.7% | |
| MEDP | Medpace Holdings, Inc. | $1,385,000 | -12.7% | 18,871 | 0.0% | 0.06% | +5.0% | |
| THC | Sell | Tenet Healthcare Corporation | $1,393,000 | -67.7% | 96,736 | -14.7% | 0.06% | -61.3% |
| HQY | Sell | HealthEquity, Inc. | $1,382,000 | -41.3% | 27,310 | -14.1% | 0.06% | -30.3% |
| EXAS | New | Exact Sciences Corporation | $1,342,000 | – | 23,133 | +100.0% | 0.06% | – |
| AUPH | Aurinia Pharmaceuticals Inc. | $1,317,000 | -28.4% | 90,788 | 0.0% | 0.06% | -14.3% | |
| ESPR | Sell | Esperion Therapeutics, Inc. | $1,311,000 | -89.7% | 41,577 | -80.5% | 0.06% | -87.8% |
| DHC | Diversified Healthcare Trust | $1,299,000 | -57.0% | 357,720 | 0.0% | 0.06% | -48.2% | |
| GLPG | Galapagos NVsponsored adr | $1,282,000 | -5.2% | 6,543 | 0.0% | 0.06% | +13.7% | |
| RVNC | Revance Therapeutics, Inc. | $1,270,000 | -8.8% | 85,840 | 0.0% | 0.06% | +7.5% | |
| HALO | New | Halozyme Therapeutics, Inc. | $1,258,000 | – | 69,917 | +100.0% | 0.06% | – |
| EVH | Evolent Health, Inc. | $1,254,000 | -40.0% | 231,027 | 0.0% | 0.06% | -27.8% | |
| ACIU | AC Immune SAshares | $1,187,000 | -18.9% | 171,813 | 0.0% | 0.05% | -1.8% | |
| WVE | Buy | WaVe Life Sciences Ltd.shares | $1,201,000 | +49.8% | 128,146 | +28.1% | 0.05% | +80.0% |
| AVRO | AVROBIO, Inc. | $1,165,000 | -22.7% | 74,874 | 0.0% | 0.05% | -7.0% | |
| ARNA | Arena Pharmaceuticals, Inc. | $1,176,000 | -7.5% | 28,002 | 0.0% | 0.05% | +10.4% | |
| HOLX | Sell | Hologic, Inc. | $1,143,000 | -48.7% | 32,564 | -23.7% | 0.05% | -38.1% |
| UHT | Buy | Universal Health Realty Income Trustshares | $1,135,000 | +68.4% | 11,258 | +96.1% | 0.05% | +104.0% |
| BBIO | BridgeBio Pharma, Inc. | $1,138,000 | -17.2% | 39,228 | 0.0% | 0.05% | -1.9% | |
| KOD | New | Kodiak Sciences Inc. | $1,104,000 | – | 23,153 | +100.0% | 0.05% | – |
| OVID | Ovid Therapeutics Inc.sponsored adr | $1,111,000 | -28.2% | 372,733 | 0.0% | 0.05% | -15.3% | |
| VRNA | Sell | Verona Pharma plcsponsored adr | $1,043,000 | -34.0% | 253,179 | -7.9% | 0.05% | -21.7% |
| QTNT | Quotient Ltd. | $1,027,000 | -58.5% | 260,030 | 0.0% | 0.05% | -51.1% | |
| CLLS | Cellectissponsored adr | $1,013,000 | -46.3% | 110,147 | 0.0% | 0.05% | -35.2% | |
| EIDX | Eidos Therapeutics, Inc. | $980,000 | -14.6% | 20,000 | 0.0% | 0.04% | +2.3% | |
| GRFS | New | Grifols, S.A.sponsored adr | $954,000 | – | 47,373 | +100.0% | 0.04% | – |
| SGMO | Sangamo Therapeutics, Inc. | $954,000 | -23.9% | 149,835 | 0.0% | 0.04% | -8.5% | |
| AERI | Aerie Pharmaceuticals, Inc. | $900,000 | -44.2% | 66,688 | 0.0% | 0.04% | -32.8% | |
| MYOK | MyoKardia, Inc. | $905,000 | -35.7% | 19,300 | 0.0% | 0.04% | -22.6% | |
| MDGL | Madrigal Pharmaceuticals, Inc. | $891,000 | -26.7% | 13,340 | 0.0% | 0.04% | -13.0% | |
| XLV | Sell | Health Care Select Sector SPDR Fundsbi healthcare | $891,000 | -83.7% | 10,055 | -81.3% | 0.04% | -80.7% |
| PTLA | Sell | Portola Pharmaceuticals, Inc.sponsored adr | $779,000 | -79.8% | 109,246 | -32.5% | 0.04% | -76.0% |
| AXNX | Axonics Modulation Technologies, Inc. | $714,000 | -8.3% | 28,100 | 0.0% | 0.03% | +10.3% | |
| RGNX | Sell | REGENXBIO Inc. | $703,000 | -51.7% | 21,700 | -38.9% | 0.03% | -41.8% |
| RUBY | Buy | Rubius Therapeutics, Inc. | $694,000 | +6.8% | 155,982 | +128.1% | 0.03% | +24.0% |
| SNR | Buy | New Senior Investment Group Inc. | $656,000 | -45.7% | 256,398 | +62.2% | 0.03% | -34.8% |
| NTLA | Intellia Therapeutics, Inc. | $673,000 | -16.7% | 55,050 | 0.0% | 0.03% | -3.2% | |
| PBYI | Puma Biotechnology, Inc. | $602,000 | -3.5% | 71,340 | 0.0% | 0.03% | +12.5% | |
| CHCT | Community Healthcare Trust Incorporated | $570,000 | -10.8% | 14,900 | 0.0% | 0.03% | +8.3% | |
| IMGN | ImmunoGen, Inc. | $574,000 | -33.2% | 168,190 | 0.0% | 0.03% | -18.8% | |
| MTEM | Molecular Templates, Inc. | $562,000 | -5.1% | 42,313 | 0.0% | 0.02% | +13.6% | |
| PRGO | Perrigo Company plcshares | $520,000 | -7.0% | 10,818 | 0.0% | 0.02% | +14.3% | |
| ZYME | Zymeworks Inc. | $539,000 | -22.0% | 15,192 | 0.0% | 0.02% | -7.7% | |
| NHI | New | National Health Investors, Inc. | $497,000 | – | 10,038 | +100.0% | 0.02% | – |
| MOR | MorphoSys AGsponsored ads | $476,000 | -31.2% | 19,390 | 0.0% | 0.02% | -15.4% | |
| MNLO | New | Menlo Therapeutics Inc. | $478,000 | – | 178,181 | +100.0% | 0.02% | – |
| CDTX | Buy | Cidara Therapeutics, Inc. | $484,000 | -20.7% | 195,256 | +23.0% | 0.02% | -4.3% |
| MIST | Sell | Milestone Pharmaceuticals Inc. | $392,000 | -96.7% | 213,310 | -71.4% | 0.02% | -96.0% |
| CYH | Sell | Community Health Systems, Inc. | $393,000 | -33.5% | 117,735 | -42.3% | 0.02% | -18.2% |
| NVAX | Novavax, Inc. | $388,000 | +240.4% | 28,550 | 0.0% | 0.02% | +350.0% | |
| CLSD | Clearside Biomedical, Inc. | $281,000 | -41.3% | 165,330 | 0.0% | 0.01% | -27.8% | |
| MRUS | Merus N.V. | $257,000 | -14.0% | 21,215 | 0.0% | 0.01% | +9.1% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $267,000 | -36.0% | 114,670 | 0.0% | 0.01% | -25.0% | |
| TPTX | Turning Point Therapeutics, Inc. | $254,000 | -28.2% | 5,677 | 0.0% | 0.01% | -15.4% | |
| CBAY | CymaBay Therapeutics, Inc. | $130,000 | -24.9% | 88,102 | 0.0% | 0.01% | -14.3% | |
| ARPO | Aerpio Pharmaceuticals, Inc. | $142,000 | -11.8% | 257,554 | 0.0% | 0.01% | 0.0% | |
| MGTA | Magenta Therapeutics, Inc. | $105,000 | -58.7% | 16,757 | 0.0% | 0.01% | -50.0% | |
| ABIO | ARCA biopharma, Inc. | $100,000 | -51.5% | 36,068 | 0.0% | 0.01% | -37.5% | |
| MNKKQ | Mallinckrodt plcsponsored adr | $65,000 | -43.5% | 32,980 | 0.0% | 0.00% | -25.0% | |
| FVE | New | Five Star Senior Living Inc. | $67,000 | – | 24,237 | +100.0% | 0.00% | – |
| TTPH | Tetraphase Pharmaceuticals, Inc. | $55,000 | -54.5% | 42,965 | 0.0% | 0.00% | -60.0% | |
| CLDX | Celldex Therapeutics, Inc. | $12,000 | -25.0% | 7,053 | 0.0% | 0.00% | 0.0% | |
| VIE | New | Viela Bio, Inc. | $19,000 | – | 500 | +100.0% | 0.00% | – |
| New | Bellicum Pharmaceuticals, Inc. | $28,000 | – | 6,000 | +100.0% | 0.00% | – | |
| QHCCQ | Quorum Health Corporation | $11,000 | -52.2% | 23,725 | 0.0% | 0.00% | -100.0% | |
| BLCM | Exit | Bellicum Pharmaceuticals, Inc. | $0 | – | -60,000 | -100.0% | -0.00% | – |
| ADAP | Exit | Adaptimmune Therapeutics plcsponsored adr | $0 | – | -77,061 | -100.0% | -0.00% | – |
| MYGN | Exit | Myriad Genetics, Inc. | $0 | – | -18,805 | -100.0% | -0.02% | – |
| FOMX | Exit | Foamix Pharmaceuticals Ltdshares | $0 | – | -300,781 | -100.0% | -0.04% | – |
| XENE | Exit | Xenon Pharmaceuticals Inc. | $0 | – | -96,961 | -100.0% | -0.05% | – |
| DERM | Exit | Dermira, Inc. | $0 | – | -89,200 | -100.0% | -0.05% | – |
| MASI | Exit | Masimo Corporation | $0 | – | -21,773 | -100.0% | -0.13% | – |
| ARQL | Exit | ArQule, Inc. | $0 | – | -220,409 | -100.0% | -0.17% | – |
| IBB | Exit | iShares Nasdaq Biotechnology ETFnasdaq biotech | $0 | – | -38,834 | -100.0% | -0.18% | – |
| XBI | Exit | SPDR S&P Biotech ETFs&p biotech etf | $0 | – | -68,037 | -100.0% | -0.24% | – |
| MDCO | Exit | The Medicines Company | $0 | – | -120,670 | -100.0% | -0.39% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2020-05-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.