$2.45 Billion is the total value of Tekla Capital Management LLC's 197 reported holdings in Q2 2019. The portfolio turnover from Q1 2019 to Q2 2019 was 14.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CELG | Celgene Corp. | $136,230,000 | -2.0% | 1,473,710 | 0.0% | 5.56% | -1.5% | |
| AMGN | Buy | Amgen Inc. | $134,461,000 | +0.5% | 729,658 | +3.6% | 5.49% | +1.0% |
| GILD | Buy | Gilead Sciences, Inc. | $124,048,000 | +9.1% | 1,836,112 | +5.0% | 5.06% | +9.6% |
| JNJ | Sell | Johnson & Johnson | $123,960,000 | -1.3% | 890,004 | -0.9% | 5.06% | -0.8% |
| VRTX | Buy | Vertex Pharmaceuticals Inc. | $89,807,000 | +10.0% | 489,734 | +10.4% | 3.66% | +10.6% |
| PFE | Sell | Pfizer Inc. | $89,597,000 | +1.9% | 2,068,265 | -0.1% | 3.66% | +2.4% |
| MRK | Buy | Merck & Co., Inc. | $84,998,000 | +2.9% | 1,013,695 | +2.1% | 3.47% | +3.4% |
| UNH | Unitedhealth Group Inc. | $79,092,000 | -1.3% | 324,133 | 0.0% | 3.23% | -0.8% | |
| ILMN | Sell | Illumina, Inc. | $73,067,000 | -1.0% | 198,471 | -16.4% | 2.98% | -0.5% |
| BIIB | Sell | Biogen Inc. | $52,548,000 | -29.3% | 224,690 | -28.5% | 2.14% | -28.9% |
| ALXN | Buy | Alexion Pharmaceuticals, Inc. | $52,394,000 | +3.2% | 400,014 | +6.5% | 2.14% | +3.6% |
| REGN | Buy | Regeneron Pharmaceuticals, Inc. | $52,261,000 | -10.1% | 166,968 | +18.0% | 2.13% | -9.6% |
| MDT | Sell | Medtronic plcshares | $46,751,000 | +4.3% | 480,035 | -2.4% | 1.91% | +4.8% |
| INCY | Sell | Incyte Corp. | $43,409,000 | -4.6% | 510,933 | -3.4% | 1.77% | -4.2% |
| ABT | Buy | Abbott Laboratories | $42,399,000 | +16.0% | 504,148 | +10.3% | 1.73% | +16.6% |
| TMO | Sell | Thermo Fisher Scientific Inc. | $39,999,000 | +2.4% | 136,198 | -4.6% | 1.63% | +2.8% |
| BMY | Bristol-Myers Squibb Company | $33,470,000 | -4.9% | 738,044 | 0.0% | 1.37% | -4.5% | |
| CVS | Buy | CVS Health Corp. | $31,354,000 | +14.8% | 575,401 | +13.6% | 1.28% | +15.3% |
| ISRG | Buy | Intuitive Surgical, Inc. | $29,204,000 | +27.1% | 55,675 | +38.2% | 1.19% | +27.8% |
| ANTM | Sell | Anthem, Inc. | $29,196,000 | -28.0% | 103,456 | -26.8% | 1.19% | -27.7% |
| ZTS | Sell | Zoetis Inc.class a | $28,212,000 | +9.0% | 248,584 | -3.3% | 1.15% | +9.5% |
| LLY | Sell | Eli Lilly and Co. | $28,052,000 | -26.8% | 253,199 | -14.3% | 1.14% | -26.4% |
| BSX | Buy | Boston Scientific Corporation | $27,174,000 | +49.5% | 632,250 | +33.5% | 1.11% | +50.3% |
| NVS | Buy | Novartis AGsponsored adr | $25,297,000 | -5.0% | 277,047 | +0.1% | 1.03% | -4.5% |
| ABBV | Buy | AbbVie Inc. | $24,239,000 | -6.1% | 333,316 | +4.1% | 0.99% | -5.6% |
| AGN | Sell | Allergan plcshares | $24,157,000 | -14.6% | 144,281 | -25.3% | 0.99% | -14.2% |
| DHR | Danaher Corp. | $22,714,000 | +8.3% | 158,931 | 0.0% | 0.93% | +8.8% | |
| SRPT | Sarepta Therapeutics, Inc. | $22,465,000 | +27.5% | 147,847 | 0.0% | 0.92% | +28.1% | |
| SYK | Sell | Stryker Corporation | $21,164,000 | -12.9% | 102,950 | -16.3% | 0.86% | -12.5% |
| BMRN | Buy | BioMarin Pharmaceutical Inc. | $21,050,000 | +6.7% | 245,763 | +10.7% | 0.86% | +7.2% |
| SGEN | Seattle Genetics, Inc. | $20,066,000 | -5.5% | 289,925 | 0.0% | 0.82% | -5.0% | |
| CI | Cigna Corporation | $18,395,000 | -2.0% | 116,756 | 0.0% | 0.75% | -1.6% | |
| MYL | Mylan N.V.shares | $17,958,000 | -32.8% | 943,152 | 0.0% | 0.73% | -32.5% | |
| NBIX | Sell | Neurocrine Biosciences, Inc. | $17,484,000 | -10.5% | 207,078 | -6.6% | 0.71% | -10.1% |
| IDXX | Sell | IDEXX Laboratories, Inc. | $17,003,000 | +19.5% | 61,754 | -3.0% | 0.69% | +20.1% |
| SAGE | Buy | Sage Therapeutics, Inc. | $15,406,000 | +21.3% | 84,145 | +5.4% | 0.63% | +21.9% |
| PRAH | Buy | PRA Health Sciences, Inc. | $15,170,000 | -4.2% | 153,003 | +6.6% | 0.62% | -3.7% |
| ARRY | Sell | Array BioPharma Inc. | $15,005,000 | +69.0% | 323,883 | -11.1% | 0.61% | +69.5% |
| BDX | Sell | Becton, Dickinson and Co. | $14,727,000 | -4.5% | 58,438 | -5.3% | 0.60% | -4.0% |
| EXEL | Exelixis, Inc. | $14,499,000 | -10.2% | 678,467 | 0.0% | 0.59% | -9.8% | |
| BAX | Buy | Baxter International Inc. | $14,472,000 | +29.3% | 176,698 | +28.4% | 0.59% | +29.9% |
| AZN | Sell | AstraZeneca PLCsponsored adr | $13,829,000 | -5.2% | 334,998 | -7.2% | 0.56% | -4.9% |
| BLUE | Buy | bluebird bio, Inc. | $12,964,000 | -9.5% | 101,918 | +12.0% | 0.53% | -9.1% |
| EW | Buy | Edwards Lifesciences Corp. | $12,889,000 | +18.6% | 69,769 | +22.8% | 0.53% | +19.3% |
| MCK | Buy | McKesson Corp. | $12,860,000 | +55.4% | 95,691 | +35.3% | 0.52% | +56.2% |
| HUM | Buy | Humana Inc. | $12,767,000 | +34.5% | 48,122 | +34.9% | 0.52% | +35.3% |
| WELL | Sell | Welltower Inc. | $12,419,000 | -32.6% | 152,322 | -35.8% | 0.51% | -32.2% |
| NVO | Sell | Novo Nordisk A/Ssponsored adr | $12,301,000 | -6.5% | 241,000 | -4.2% | 0.50% | -6.0% |
| HCA | HCA Healthcare, Inc. | $12,107,000 | +3.7% | 89,569 | 0.0% | 0.49% | +4.2% | |
| ABC | Buy | AmerisourceBergen Corp. | $11,960,000 | +89.8% | 140,273 | +77.1% | 0.49% | +90.6% |
| BGNE | BeiGene, Ltd.sponsored adr | $11,761,000 | -6.1% | 94,889 | 0.0% | 0.48% | -5.7% | |
| ALNY | Buy | Alnylam Pharmaceuticals, Inc. | $11,709,000 | -6.1% | 161,372 | +20.9% | 0.48% | -5.7% |
| GWPH | Buy | GW Pharmaceuticals PLCads | $11,119,000 | +89.0% | 64,499 | +84.9% | 0.45% | +90.0% |
| FGEN | Buy | FibroGen, Inc. | $11,038,000 | +15.6% | 244,320 | +39.0% | 0.45% | +16.0% |
| AMRN | Sell | Amarin Corporation plcsponsored adr | $10,728,000 | -15.5% | 553,295 | -9.5% | 0.44% | -15.0% |
| MDCO | Sell | The Medicines Company | $10,142,000 | +23.7% | 278,092 | -5.2% | 0.41% | +24.3% |
| NKTR | Nektar Therapeutics | $10,093,000 | +5.9% | 283,679 | 0.0% | 0.41% | +6.5% | |
| OHI | Sell | Omega Healthcare Investors, Inc. | $10,024,000 | -22.8% | 272,766 | -19.8% | 0.41% | -22.4% |
| JAZZ | Jazz Pharmaceuticals plcshares | $9,619,000 | -0.3% | 67,471 | 0.0% | 0.39% | +0.3% | |
| ZBH | Zimmer Biomet Holdings, Inc. | $9,378,000 | -7.8% | 79,654 | 0.0% | 0.38% | -7.3% | |
| SBRA | Sabra Health Care REIT, Inc. | $9,180,000 | +1.1% | 466,247 | 0.0% | 0.38% | +1.6% | |
| BPMC | Sell | Blueprint Medicines Corporation | $8,959,000 | -3.3% | 94,976 | -17.9% | 0.37% | -2.7% |
| GSK | GlaxoSmithKline PLCshares | $8,752,000 | -4.2% | 218,700 | 0.0% | 0.36% | -3.8% | |
| ESPR | Esperion Therapeutics, Inc. | $8,588,000 | +15.9% | 184,607 | 0.0% | 0.35% | +16.3% | |
| ABMD | Buy | ABIOMED, Inc. | $8,522,000 | +24.4% | 32,716 | +36.4% | 0.35% | +25.2% |
| ASND | Buy | Ascendis Pharma A/Ssponsored adr | $8,480,000 | +17.4% | 73,647 | +20.0% | 0.35% | +18.1% |
| CRSP | CRISPR Therapeutics AGnamen akt | $8,400,000 | +31.8% | 178,348 | 0.0% | 0.34% | +32.4% | |
| IONS | Buy | Ionis Pharmaceuticals, Inc. | $8,201,000 | -7.9% | 127,598 | +16.3% | 0.34% | -7.5% |
| XBI | SPDR S&P Biotech ETFs&p biotech etf | $7,808,000 | -3.1% | 89,022 | 0.0% | 0.32% | -2.4% | |
| ALGN | Align Technology, Inc. | $7,740,000 | -3.7% | 28,278 | 0.0% | 0.32% | -3.4% | |
| XLRN | Acceleron Pharma Inc. | $7,739,000 | -11.8% | 188,388 | 0.0% | 0.32% | -11.2% | |
| XRAY | Sell | DENTSPLY SIRONA Inc. | $7,407,000 | -4.6% | 126,921 | -18.9% | 0.30% | -4.1% |
| STRO | Sutro Biopharma, Inc. | $7,298,000 | -0.1% | 641,268 | 0.0% | 0.30% | +0.3% | |
| TEVA | Sell | Teva Pharmaceutical Industries Ltd.sponsored adr | $7,253,000 | -48.1% | 785,851 | -11.8% | 0.30% | -47.8% |
| AGIO | Buy | Agios Pharmaceuticals, Inc. | $7,250,000 | +17.1% | 145,342 | +58.4% | 0.30% | +17.9% |
| SNN | Sell | Smith & Nephew plcshares | $6,998,000 | -5.9% | 160,734 | -13.3% | 0.29% | -5.3% |
| PIRS | Sell | Pieris Pharmaceuticals, Inc. | $6,812,000 | -2.6% | 1,449,269 | -30.6% | 0.28% | -2.1% |
| VTR | Ventas, Inc. | $6,732,000 | +7.1% | 98,496 | 0.0% | 0.28% | +7.8% | |
| LTC | LTC Properties, Inc. | $6,640,000 | -0.3% | 145,421 | 0.0% | 0.27% | +0.4% | |
| CHRS | Sell | Coherus Biosciences, Inc. | $6,440,000 | +49.8% | 291,419 | -7.5% | 0.26% | +50.3% |
| RMD | Sell | ResMed Inc. | $6,359,000 | -11.3% | 52,110 | -24.4% | 0.26% | -11.0% |
| PTCT | Buy | PTC Therapeutics, Inc. | $6,282,000 | +143.1% | 139,608 | +103.4% | 0.26% | +143.8% |
| GLPG | Galapagos NVsponsored adr | $6,256,000 | +9.5% | 48,525 | 0.0% | 0.26% | +9.9% | |
| ACHC | Acadia Healthcare Co., Inc. | $6,052,000 | +19.3% | 173,155 | 0.0% | 0.25% | +19.9% | |
| ZGNX | Buy | Zogenix, Inc. | $5,932,000 | +20.1% | 124,148 | +38.3% | 0.24% | +20.4% |
| LH | Sell | Laboratory Corporation of America Holdingssponsored adr | $5,433,000 | -22.2% | 31,424 | -31.2% | 0.22% | -21.8% |
| IMMU | Buy | Immunomedics, Inc. | $5,400,000 | -2.3% | 389,313 | +35.3% | 0.22% | -1.8% |
| DOC | Physicians Realty Trust | $5,300,000 | -7.3% | 303,908 | 0.0% | 0.22% | -6.9% | |
| WCG | Sell | WellCare Health Plans, Inc. | $5,099,000 | -2.0% | 17,886 | -7.3% | 0.21% | -1.4% |
| EPZM | Buy | Epizyme, Inc. | $5,015,000 | +39.8% | 399,604 | +38.1% | 0.20% | +40.4% |
| LGND | Buy | Ligand Pharmaceuticals Inc. | $5,029,000 | +33.8% | 44,055 | +47.4% | 0.20% | +34.0% |
| IOVA | Sell | Iovance Biotherapeutics, Inc. | $4,881,000 | +136.6% | 199,073 | -8.2% | 0.20% | +136.9% |
| TECH | Bio-Techne Corporation | $4,524,000 | +5.0% | 21,701 | 0.0% | 0.18% | +5.7% | |
| ALKS | Alkermes plcshares | $4,464,000 | -38.2% | 198,048 | 0.0% | 0.18% | -38.1% | |
| STE | Sell | STERIS plcshares | $4,315,000 | -29.8% | 28,981 | -39.6% | 0.18% | -29.6% |
| ICPT | Sell | Intercept Pharmaceuticals, Inc. | $4,285,000 | -35.4% | 53,857 | -9.1% | 0.18% | -34.9% |
| ACAD | Buy | ACADIA Pharmaceuticals Inc. | $4,281,000 | +52.2% | 160,147 | +52.9% | 0.18% | +53.5% |
| BHC | Bausch Health Co. Inc. | $4,257,000 | +2.1% | 168,812 | 0.0% | 0.17% | +3.0% | |
| ANAB | Buy | AnaptysBio, Inc. | $4,220,000 | -12.3% | 74,798 | +13.6% | 0.17% | -11.8% |
| UTHR | Buy | United Therapeutics Corporationclass b | $4,223,000 | -12.8% | 54,094 | +31.1% | 0.17% | -12.7% |
| MASI | Buy | Masimo Corp. | $4,127,000 | +178.5% | 27,732 | +158.8% | 0.17% | +180.0% |
| ARGX | argenx SEsponsored adr | $4,018,000 | +13.4% | 28,381 | 0.0% | 0.16% | +13.9% | |
| FOLD | Amicus Therapeutics, Inc. | $3,926,000 | -8.2% | 314,597 | 0.0% | 0.16% | -8.0% | |
| HZNP | New | Horizon Therapeutics plcshares | $3,789,000 | – | 157,473 | +100.0% | 0.16% | – |
| THC | Buy | Tenet Healthcare Corp. | $3,774,000 | -7.3% | 182,671 | +29.4% | 0.15% | -6.7% |
| PHG | Koninklijke Philips N.V.ny reg sh | $3,722,000 | +6.7% | 85,400 | 0.0% | 0.15% | +7.0% | |
| SNY | Sell | Sanofisponsored adr | $3,719,000 | -53.3% | 85,941 | -52.2% | 0.15% | -53.1% |
| MRUS | Sell | Merus N.V. | $3,591,000 | -23.5% | 245,114 | -22.8% | 0.15% | -23.0% |
| GBT | Sell | Global Blood Therapeutics, Inc. | $3,551,000 | -22.0% | 67,516 | -21.5% | 0.14% | -21.6% |
| NVCR | Sell | Novocure Ltd.ordinary shares | $3,419,000 | +7.6% | 54,074 | -18.0% | 0.14% | +8.5% |
| ALC | New | Alcon Inc.ordinary shares | $3,436,000 | – | 55,369 | +100.0% | 0.14% | – |
| ALBO | Sell | Albireo Pharma, Inc. | $3,390,000 | -15.8% | 105,154 | -15.9% | 0.14% | -15.9% |
| BCEL | New | Atreca, Inc. | $3,297,000 | – | 175,000 | +100.0% | 0.14% | – |
| LIVN | Buy | LivaNova PLCshares | $3,287,000 | +196.4% | 45,681 | +300.7% | 0.13% | +197.8% |
| MPW | Sell | Medical Properties Trust, Inc. | $3,262,000 | -45.9% | 187,063 | -42.6% | 0.13% | -45.7% |
| VAR | Sell | Varian Medical Systems, Inc. | $3,271,000 | -12.0% | 24,027 | -8.4% | 0.13% | -11.9% |
| TAK | Takeda Pharmaceutical SP ADRsponsored ads | $3,153,000 | -13.1% | 178,128 | 0.0% | 0.13% | -12.2% | |
| PTLA | Portola Pharmaceuticals, Inc.sponsored adr | $3,132,000 | -21.8% | 115,448 | 0.0% | 0.13% | -21.5% | |
| SNH | Senior Housing Properties Trust | $2,958,000 | -29.8% | 357,720 | 0.0% | 0.12% | -29.2% | |
| XNCR | Xencor, Inc. | $2,963,000 | +31.8% | 72,382 | 0.0% | 0.12% | +33.0% | |
| IQV | IQVIA Holdings Inc. | $2,637,000 | +11.8% | 16,391 | 0.0% | 0.11% | +12.5% | |
| DGX | Sell | Quest Diagnostics Inc. | $2,648,000 | -55.7% | 26,012 | -60.9% | 0.11% | -55.6% |
| A | New | Agilent Technologies, Inc. | $2,509,000 | – | 33,600 | +100.0% | 0.10% | – |
| RARE | Sell | Ultragenyx Pharmaceutical Inc. | $2,443,000 | -54.2% | 38,480 | -50.0% | 0.10% | -53.9% |
| NTLA | Intellia Therapeutics, Inc. | $2,460,000 | -4.2% | 150,290 | 0.0% | 0.10% | -3.8% | |
| AVDL | Avadel Pharmaceuticals plcsponsored adr | $2,354,000 | +100.7% | 814,588 | 0.0% | 0.10% | +100.0% | |
| ENDP | Endo International plcshares | $2,190,000 | -48.7% | 531,570 | 0.0% | 0.09% | -48.6% | |
| HR | Healthcare Realty Trust Inc. | $2,130,000 | -2.4% | 68,000 | 0.0% | 0.09% | -2.2% | |
| TFX | Teleflex Inc. | $2,112,000 | +9.6% | 6,379 | 0.0% | 0.09% | +10.3% | |
| HQY | New | HealthEquity, Inc. | $2,080,000 | – | 31,810 | +100.0% | 0.08% | – |
| HOLX | Buy | Hologic, Inc. | $2,051,000 | +116.8% | 42,701 | +118.5% | 0.08% | +121.1% |
| WMGI | Sell | Wright Medical Group N.V.ordinary shares | $2,043,000 | -43.4% | 68,506 | -40.3% | 0.08% | -43.5% |
| CRL | Buy | Charles River Laboratories International, Inc. | $2,010,000 | +30.1% | 14,167 | +33.1% | 0.08% | +30.2% |
| BOLD | Audentes Therapeutics, Inc. | $1,990,000 | -3.0% | 52,574 | 0.0% | 0.08% | -2.4% | |
| AERI | Sell | Aerie Pharmaceuticals, Inc. | $1,971,000 | -39.4% | 66,688 | -2.6% | 0.08% | -39.4% |
| MYOK | MyoKardia, Inc. | $1,935,000 | -3.6% | 38,600 | 0.0% | 0.08% | -3.7% | |
| ARDX | Ardelyx, Inc. | $1,720,000 | -3.9% | 639,370 | 0.0% | 0.07% | -4.1% | |
| CLLS | Sell | Cellectis SAsponsored adr | $1,718,000 | -45.9% | 110,147 | -36.3% | 0.07% | -45.7% |
| ARQL | Sell | ArQule, Inc. | $1,675,000 | +39.8% | 152,110 | -39.2% | 0.07% | +38.8% |
| ARNA | Sell | Arena Pharmaceuticals, Inc. | $1,642,000 | -29.9% | 28,002 | -46.4% | 0.07% | -29.5% |
| NTUS | New | Natus Medical Inc. | $1,573,000 | – | 61,219 | +100.0% | 0.06% | – |
| GHDX | Genomic Health, Inc. | $1,543,000 | -17.0% | 26,531 | 0.0% | 0.06% | -16.0% | |
| QURE | uniQure N.V.shares | $1,544,000 | +31.1% | 19,751 | 0.0% | 0.06% | +31.2% | |
| SYNH | Syneos Health, Inc.class a | $1,483,000 | -1.3% | 29,027 | 0.0% | 0.06% | 0.0% | |
| PTGX | Sell | Protagonist Therapeutics, Inc. | $1,469,000 | -34.1% | 121,341 | -31.6% | 0.06% | -34.1% |
| WVE | Buy | WaVe Life Sciences Ltd.shares | $1,460,000 | +23.8% | 55,955 | +84.5% | 0.06% | +25.0% |
| VRNA | Verona Pharma plcsponsored adr | $1,471,000 | -14.4% | 275,000 | 0.0% | 0.06% | -14.3% | |
| HCP | HCP, Inc. | $1,455,000 | +2.2% | 45,500 | 0.0% | 0.06% | +1.7% | |
| TXMD | New | TherapeuticsMD, Inc. | $1,409,000 | – | 541,815 | +100.0% | 0.06% | – |
| MRTX | Mirati Therapeutics, Inc. | $1,400,000 | +40.6% | 13,590 | 0.0% | 0.06% | +42.5% | |
| MDGL | Madrigal Pharmaceuticals, Inc. | $1,398,000 | -16.3% | 13,340 | 0.0% | 0.06% | -16.2% | |
| EVH | Buy | Evolent Health, Inc. | $1,385,000 | +161.3% | 174,270 | +313.5% | 0.06% | +159.1% |
| MIST | New | Milestone Pharmaceuticals, Inc. | $1,358,000 | – | 50,000 | +100.0% | 0.06% | – |
| CNCE | Buy | Concert Pharmaceuticals, Inc. | $1,330,000 | +142.7% | 110,853 | +144.4% | 0.05% | +145.5% |
| SGMO | Sell | Sangamo Therapeutics, Inc. | $1,301,000 | -43.5% | 120,768 | -50.0% | 0.05% | -43.6% |
| DPLO | Diplomat Pharmacy, Inc. | $1,308,000 | +4.8% | 214,845 | 0.0% | 0.05% | +3.9% | |
| HTA | Healthcare Trust of America, Inc. | $1,262,000 | -4.0% | 46,000 | 0.0% | 0.05% | -3.8% | |
| MTEM | Molecular Templates, Inc. | $1,203,000 | +43.7% | 144,110 | 0.0% | 0.05% | +44.1% | |
| EDIT | Sell | Editas Medicine, Inc. | $1,113,000 | -40.6% | 44,989 | -41.3% | 0.04% | -40.8% |
| ALLK | Allakos Inc. | $1,058,000 | +7.0% | 24,414 | 0.0% | 0.04% | +7.5% | |
| SNR | Sell | New Senior Investment Group Inc. | $1,062,000 | -26.1% | 158,047 | -40.1% | 0.04% | -25.9% |
| PRGO | Perrigo Company plcshares | $1,034,000 | -1.1% | 21,718 | 0.0% | 0.04% | 0.0% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $987,000 | -19.5% | 114,670 | 0.0% | 0.04% | -20.0% | |
| VKTX | Viking Therapeutics, Inc. | $946,000 | -16.5% | 114,016 | 0.0% | 0.04% | -15.2% | |
| MOR | New | MorphoSys AGsponsored ads | $957,000 | – | 39,643 | +100.0% | 0.04% | – |
| ACIU | AC Immune SAshares | $954,000 | +9.9% | 171,813 | 0.0% | 0.04% | +11.4% | |
| INGN | Buy | Inogen, Inc. | $935,000 | +22.5% | 14,000 | +75.0% | 0.04% | +22.6% |
| ADAP | Adaptimmune Therapeutics plcsponsored adr | $919,000 | -6.5% | 228,496 | 0.0% | 0.04% | -5.0% | |
| PBYI | Puma Biotechnology, Inc. | $907,000 | -67.2% | 71,340 | 0.0% | 0.04% | -67.0% | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | $814,000 | +44.6% | 30,700 | 0.0% | 0.03% | +43.5% | |
| GMRE | Global Medical REIT Inc. | $771,000 | +6.9% | 73,400 | 0.0% | 0.03% | +6.9% | |
| AFMD | Affimed N.V. | $729,000 | -31.7% | 254,000 | 0.0% | 0.03% | -30.2% | |
| ITCI | Sell | Intra-Cellular Therapies, Inc. | $715,000 | -46.7% | 55,096 | -50.0% | 0.03% | -47.3% |
| FOMX | Foamix Pharmaceuticals Ltdshares | $716,000 | -36.5% | 300,781 | 0.0% | 0.03% | -37.0% | |
| OVID | Sell | Ovid Therapeutics Inc.sponsored adr | $690,000 | -21.6% | 372,733 | -25.0% | 0.03% | -22.2% |
| RGNX | New | REGENXBIO Inc. | $658,000 | – | 12,801 | +100.0% | 0.03% | – |
| ARPO | Aerpio Pharmaceuticals, Inc. | $673,000 | +0.9% | 740,000 | 0.0% | 0.03% | 0.0% | |
| CBAY | New | CymaBay Therapeutics, Inc. | $631,000 | – | 88,102 | +100.0% | 0.03% | – |
| RARX | New | Ra Pharmaceuticals, Inc. | $577,000 | – | 19,190 | +100.0% | 0.02% | – |
| CLVS | Sell | Clovis Oncology, Inc. | $561,000 | -70.0% | 37,700 | -50.0% | 0.02% | -69.7% |
| MYGN | Myriad Genetics, Inc. | $571,000 | -16.3% | 20,549 | 0.0% | 0.02% | -17.9% | |
| CYH | Community Health Systems, Inc. | $545,000 | -28.4% | 203,935 | 0.0% | 0.02% | -29.0% | |
| RYTM | Rhythm Pharmaceuticals, Inc. | $548,000 | -19.6% | 24,890 | 0.0% | 0.02% | -21.4% | |
| CMRX | New | Chimerix, Inc. | $494,000 | – | 114,333 | +100.0% | 0.02% | – |
| FATE | New | Fate Therapeutics, Inc. | $495,000 | – | 24,379 | +100.0% | 0.02% | – |
| TTPH | Tetraphase Pharmaceuticals, Inc. | $413,000 | -64.1% | 859,322 | 0.0% | 0.02% | -63.8% | |
| IMGN | ImmunoGen, Inc. | $365,000 | -20.0% | 168,190 | 0.0% | 0.02% | -21.1% | |
| CAH | Cardinal Health, Inc. | $297,000 | -2.0% | 6,300 | 0.0% | 0.01% | 0.0% | |
| MNKKQ | Mallinckrodt plcsponsored adr | $303,000 | -57.7% | 32,980 | 0.0% | 0.01% | -58.6% | |
| ABIO | New | ARCA biopharma, Inc. | $264,000 | – | 36,068 | +100.0% | 0.01% | – |
| CDTX | Cidara Therapeutics, Inc. | $267,000 | -36.6% | 158,784 | 0.0% | 0.01% | -35.3% | |
| NVAX | New | Novavax, Inc. | $167,000 | – | 28,550 | +100.0% | 0.01% | – |
| CLSD | Clearside Biomedical, Inc. | $161,000 | -29.4% | 165,330 | 0.0% | 0.01% | -22.2% | |
| Trillium Therapeutics Inc. | $146,000 | -50.3% | 446,099 | 0.0% | 0.01% | -50.0% | ||
| BLCM | Bellicum Pharmaceuticals, Inc. | $102,000 | -49.5% | 60,000 | 0.0% | 0.00% | -50.0% | |
| QHCCQ | Quorum Health Corp. | $33,000 | 0.0% | 23,725 | 0.0% | 0.00% | 0.0% | |
| CLDX | Celldex Therapeutics, Inc. | $19,000 | -45.7% | 7,053 | 0.0% | 0.00% | 0.0% | |
| JNCE | Exit | Jounce Therapeutics, Inc. | $0 | – | -10,127 | -100.0% | -0.00% | – |
| NUVA | Exit | NuVasive, Inc. | $0 | – | -3,816 | -100.0% | -0.01% | – |
| ABIO | Exit | ARCA biopharma, Inc. | $0 | – | -811,227 | -100.0% | -0.01% | – |
| NVAX | Exit | Novavax, Inc. | $0 | – | -571,000 | -100.0% | -0.01% | – |
| ALQA | Exit | Alliqua BioMedical, Inc. | $0 | – | -148,500 | -100.0% | -0.02% | – |
| DNLI | Exit | Denali Therapeutics Inc. | $0 | – | -19,372 | -100.0% | -0.02% | – |
| HZNP | Exit | Horizon Pharma plcshares | $0 | – | -19,350 | -100.0% | -0.02% | – |
| ATNX | Exit | Athenex, Inc. | $0 | – | -45,530 | -100.0% | -0.02% | – |
| SNDX | Exit | Syndax Pharmaceuticals, Inc. | $0 | – | -143,438 | -100.0% | -0.03% | – |
| RDY | Exit | Dr. Reddy's Laboratories Ltd.sponsored adr | $0 | – | -28,950 | -100.0% | -0.05% | – |
| MRNS | Exit | Marinus Pharmaceuticals, Inc. | $0 | – | -328,436 | -100.0% | -0.06% | – |
| AKBA | Exit | Akebia Therapeutics, Inc. | $0 | – | -213,942 | -100.0% | -0.07% | – |
| CNC | Exit | Centene Corporation | $0 | – | -128,295 | -100.0% | -0.28% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-08-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.