$2.64 Billion is the total value of Tekla Capital Management LLC's 180 reported holdings in Q2 2018. The portfolio turnover from Q1 2018 to Q2 2018 was 15.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GILD | Gilead Sciences, Inc. | $146,192,000 | -6.0% | 2,063,699 | 0.0% | 5.55% | -8.3% | |
| AMGN | Amgen Inc. | $129,322,000 | +8.3% | 700,588 | 0.0% | 4.91% | +5.6% | |
| BIIB | Buy | Biogen Inc. | $117,244,000 | +13.1% | 403,955 | +6.7% | 4.45% | +10.3% |
| JNJ | Johnson & Johnson | $108,367,000 | -5.3% | 893,082 | 0.0% | 4.11% | -7.6% | |
| UNH | Buy | Unitedhealth Group Incorporated | $104,347,000 | +38.4% | 425,317 | +20.7% | 3.96% | +35.1% |
| CELG | Sell | Celgene Corporation | $99,392,000 | -17.6% | 1,251,470 | -7.5% | 3.77% | -19.6% |
| VRTX | Sell | Vertex Pharmaceuticals Incorporated | $98,835,000 | -1.2% | 581,522 | -5.3% | 3.75% | -3.6% |
| PFE | Buy | Pfizer Inc. | $85,609,000 | +17.6% | 2,359,687 | +15.0% | 3.25% | +14.7% |
| ILMN | Sell | Illumina, Inc. | $79,456,000 | +14.0% | 284,492 | -3.5% | 3.02% | +11.2% |
| MRK | Merck & Co., Inc. | $77,940,000 | +11.4% | 1,284,022 | 0.0% | 2.96% | +8.8% | |
| MYL | Sell | Mylan N.V.shares | $59,885,000 | -15.8% | 1,657,017 | -4.1% | 2.27% | -17.8% |
| ALXN | Sell | Alexion Pharmaceuticals, Inc. | $54,429,000 | -2.1% | 438,416 | -12.1% | 2.06% | -4.5% |
| REGN | Buy | Regeneron Pharmaceuticals, Inc. | $50,450,000 | +5.0% | 146,237 | +4.8% | 1.91% | +2.4% |
| ABBV | Buy | AbbVie Inc. | $47,590,000 | +11.6% | 513,658 | +14.0% | 1.81% | +8.9% |
| INCY | Incyte Corporation | $43,245,000 | -19.6% | 645,442 | 0.0% | 1.64% | -21.6% | |
| AGN | Allergan plcshares | $41,486,000 | -0.9% | 248,836 | 0.0% | 1.57% | -3.4% | |
| ABT | Sell | Abbott Laboratories | $38,242,000 | -20.1% | 627,019 | -21.5% | 1.45% | -22.0% |
| MDT | Sell | Medtronic plcshares | $36,272,000 | -13.4% | 423,693 | -18.9% | 1.38% | -15.5% |
| BMY | Buy | Bristol-Myers Squibb Company | $36,028,000 | +8.3% | 651,030 | +23.8% | 1.37% | +5.7% |
| LLY | Sell | Eli Lilly and Company | $33,288,000 | -11.6% | 390,108 | -19.9% | 1.26% | -13.8% |
| TMO | Buy | Thermo Fisher Scientific Inc. | $31,629,000 | +3.6% | 152,695 | +3.3% | 1.20% | +1.1% |
| HUM | Sell | Humana Inc. | $31,267,000 | -2.0% | 105,053 | -11.5% | 1.19% | -4.4% |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $30,995,000 | +10.5% | 234,489 | -38.1% | 1.18% | +7.8% |
| IDXX | Sell | IDEXX Laboratories, Inc. | $28,247,000 | -3.6% | 129,608 | -15.3% | 1.07% | -5.9% |
| AZN | Buy | AstraZeneca PLCsponsored adr | $27,347,000 | +76.7% | 778,888 | +76.0% | 1.04% | +72.4% |
| NBIX | Sell | Neurocrine Biosciences, Inc. | $26,502,000 | +14.4% | 269,769 | -3.5% | 1.01% | +11.7% |
| TEVA | Buy | Teva Pharmaceutical Industries Limitedsponsored adr | $26,359,000 | +42.4% | 1,083,843 | +0.1% | 1.00% | +38.9% |
| ANTM | Buy | Anthem, Inc. | $26,334,000 | +31.0% | 110,633 | +20.9% | 1.00% | +27.7% |
| XBI | SPDR S&P Biotech ETFs&p biotech etf | $23,841,000 | +8.5% | 250,460 | 0.0% | 0.90% | +5.8% | |
| CVS | CVS Health Corporation | $23,586,000 | +3.4% | 366,521 | 0.0% | 0.90% | +0.9% | |
| SYK | Buy | Stryker Corporation | $23,072,000 | +123.1% | 136,631 | +112.6% | 0.88% | +117.9% |
| CNC | Sell | Centene Corporation | $22,772,000 | -7.4% | 184,819 | -19.7% | 0.86% | -9.7% |
| SAGE | Buy | Sage Therapeutics, Inc. | $22,480,000 | +12.0% | 143,614 | +15.2% | 0.85% | +9.2% |
| NVS | Sell | Novartis AGsponsored adr | $22,346,000 | -21.3% | 295,820 | -15.7% | 0.85% | -23.2% |
| JAZZ | Sell | Jazz Pharmaceuticals plcshares | $19,031,000 | +2.9% | 110,452 | -9.8% | 0.72% | +0.4% |
| DHR | Buy | Danaher Corporation | $19,033,000 | +159.7% | 192,871 | +157.7% | 0.72% | +153.3% |
| SGEN | Sell | Seattle Genetics, Inc. | $18,550,000 | +2.3% | 279,417 | -19.4% | 0.70% | -0.1% |
| OHI | Omega Healthcare Investors, Inc. | $17,973,000 | +14.6% | 579,785 | 0.0% | 0.68% | +11.8% | |
| AET | Buy | Aetna Inc. | $17,822,000 | +121.7% | 97,122 | +104.2% | 0.68% | +116.0% |
| SBRA | Sabra Health Care REIT, Inc. | $15,746,000 | +23.1% | 724,606 | 0.0% | 0.60% | +20.3% | |
| BSX | Boston Scientific Corporation | $14,963,000 | +19.7% | 457,585 | 0.0% | 0.57% | +16.9% | |
| GSK | Sell | GlaxoSmithKline plcshares | $14,471,000 | -6.2% | 359,000 | -9.1% | 0.55% | -8.5% |
| FOLD | Amicus Therapeutics, Inc. | $13,672,000 | +3.9% | 875,304 | 0.0% | 0.52% | +1.4% | |
| ZBH | Buy | Zimmer Biomet Holdings, Inc. | $13,244,000 | +48.0% | 118,846 | +44.8% | 0.50% | +44.5% |
| BMRN | Sell | BioMarin Pharmaceutical Inc. | $13,239,000 | -41.9% | 140,538 | -50.0% | 0.50% | -43.3% |
| MCK | McKesson Corporation | $13,180,000 | -5.3% | 98,797 | 0.0% | 0.50% | -7.6% | |
| ALNY | Alnylam Pharmaceuticals, Inc. | $12,841,000 | -17.3% | 130,376 | 0.0% | 0.49% | -19.4% | |
| BDX | Buy | Becton, Dickinson and Company | $12,691,000 | +239.4% | 52,978 | +207.0% | 0.48% | +232.4% |
| MPW | Medical Properties Trust, Inc. | $12,055,000 | +8.0% | 858,586 | 0.0% | 0.46% | +5.3% | |
| WELLPRI | Welltower Inc.6.50% preferred perpetual | $11,890,000 | +6.8% | 200,000 | 0.0% | 0.45% | +4.2% | |
| SNH | Senior Housing Properties Trustshares | $11,696,000 | +15.5% | 646,554 | 0.0% | 0.44% | +12.7% | |
| BLUE | Buy | bluebird bio, Inc. | $11,331,000 | +0.1% | 72,198 | +8.9% | 0.43% | -2.3% |
| DPLO | Diplomat Pharmacy, Inc. | $11,221,000 | +26.8% | 439,001 | 0.0% | 0.43% | +23.8% | |
| ISRG | Buy | Intuitive Surgical, Inc. | $11,234,000 | +91.4% | 23,479 | +65.1% | 0.43% | +86.8% |
| FGEN | Buy | FibroGen, Inc. | $11,156,000 | +131.5% | 178,207 | +70.8% | 0.42% | +126.2% |
| ACHC | Acadia Healthcare Company, Inc. | $11,144,000 | +4.4% | 272,400 | 0.0% | 0.42% | +1.9% | |
| PIRS | Pieris Pharmaceuticals, Inc. | $10,583,000 | -25.7% | 2,087,380 | 0.0% | 0.40% | -27.4% | |
| CRSP | Buy | CRISPR Therapeutics AG | $10,480,000 | +62.4% | 178,348 | +26.3% | 0.40% | +58.6% |
| ENDP | Buy | Endo International plcshares | $10,169,000 | +87.2% | 1,078,414 | +17.9% | 0.39% | +82.9% |
| ADAP | Adaptimmune Therapeutics plcsponsored adr | $10,154,000 | +5.7% | 855,468 | 0.0% | 0.38% | +2.9% | |
| GWPH | Sell | GW Pharmaceuticals plcads | $9,977,000 | -20.1% | 71,497 | -35.5% | 0.38% | -21.9% |
| BAX | Buy | Baxter International Inc.sponsored adr | $9,904,000 | +281.1% | 134,124 | +235.6% | 0.38% | +272.3% |
| EW | Edwards Lifesciences Corporation | $9,648,000 | +4.3% | 66,275 | 0.0% | 0.37% | +1.7% | |
| MRUS | Sell | Merus N.V. | $9,425,000 | +6.1% | 414,115 | -13.6% | 0.36% | +3.8% |
| BPMC | Buy | Blueprint Medicines Corporation | $9,268,000 | +36.2% | 146,001 | +96.7% | 0.35% | +32.8% |
| NKTR | Buy | Nektar Therapeutics | $9,218,000 | -30.3% | 188,769 | +51.6% | 0.35% | -32.0% |
| EXEL | Buy | Exelixis, Inc. | $9,211,000 | +7.0% | 428,022 | +10.1% | 0.35% | +4.5% |
| CLLS | Buy | Cellectis S.A.sponsored adr | $8,995,000 | +0.8% | 317,950 | +12.3% | 0.34% | -1.7% |
| LTC | LTC Properties, Inc. | $8,961,000 | +12.5% | 209,673 | 0.0% | 0.34% | +9.7% | |
| MDCO | Sell | The Medicines Company | $8,762,000 | -4.4% | 238,741 | -14.2% | 0.33% | -7.0% |
| BGNE | Buy | BeiGene, Ltd.sponsored adr | $8,422,000 | +1.3% | 54,785 | +10.7% | 0.32% | -0.9% |
| Aegerion Pharmaceuticals, Inc.note 2.00% 8/15/19 | $8,436,000 | -15.7% | 13,000,000 | 0.0% | 0.32% | -17.7% | ||
| XLRN | Sell | Acceleron Pharma Inc. | $8,286,000 | -22.4% | 170,766 | -37.5% | 0.31% | -24.3% |
| ESRX | Express Scripts Holding Company | $8,223,000 | +11.8% | 106,500 | 0.0% | 0.31% | +9.1% | |
| GLPG | Sell | Galapagos NVsponsored adr | $8,003,000 | -16.1% | 86,815 | -9.2% | 0.30% | -18.1% |
| ABC | AmerisourceBergen Corporation | $7,905,000 | -1.1% | 92,707 | 0.0% | 0.30% | -3.5% | |
| HCA | Sell | HCA Healthcare, Inc. | $7,704,000 | -13.6% | 75,090 | -18.3% | 0.29% | -15.9% |
| ESPR | Esperion Therapeutics, Inc. | $7,418,000 | -45.8% | 189,287 | 0.0% | 0.28% | -47.2% | |
| SNY | Sanofi | $7,198,000 | -0.2% | 179,900 | 0.0% | 0.27% | -2.5% | |
| ALKS | Sell | Alkermes plcshares | $7,040,000 | -42.2% | 171,042 | -18.6% | 0.27% | -43.7% |
| WMGI | Wright Medical Group N.V.ordinary shares | $6,926,000 | +30.9% | 266,781 | 0.0% | 0.26% | +27.7% | |
| CI | Sell | Cigna Corporation | $6,876,000 | -27.5% | 40,461 | -28.5% | 0.26% | -29.3% |
| EPZM | Epizyme, Inc. | $6,576,000 | -23.7% | 485,325 | 0.0% | 0.25% | -25.4% | |
| NVO | Novo Nordisk A/Ssponsored adr | $6,268,000 | -6.3% | 135,900 | 0.0% | 0.24% | -8.5% | |
| DOC | Buy | Physicians Realty Trust | $6,233,000 | +50.9% | 391,016 | +47.4% | 0.24% | +47.2% |
| SHPG | Sell | Shire plcshares | $6,113,000 | -64.6% | 36,216 | -68.7% | 0.23% | -65.5% |
| RMD | Buy | ResMed Inc. | $6,073,000 | +82.4% | 58,630 | +73.4% | 0.23% | +76.9% |
| RARE | Sell | Ultragenyx Pharmaceutical Inc. | $5,916,000 | -21.9% | 76,958 | -48.2% | 0.22% | -24.1% |
| VTR | Buy | Ventas, Inc. | $5,609,000 | +28.7% | 98,496 | +11.9% | 0.21% | +26.0% |
| THC | Tenet Healthcare Corporation | $5,522,000 | +38.4% | 164,500 | 0.0% | 0.21% | +35.5% | |
| AVDL | Avadel Pharmaceuticals plcsponsored adr | $4,993,000 | -15.9% | 814,588 | 0.0% | 0.19% | -18.2% | |
| PBYI | Buy | Puma Biotechnology, Inc. | $4,930,000 | +29.4% | 83,340 | +48.9% | 0.19% | +26.4% |
| EDIT | Editas Medicine, Inc. | $4,937,000 | +8.1% | 137,801 | 0.0% | 0.19% | +5.1% | |
| MASI | Buy | Masimo Corporation | $4,689,000 | +27.9% | 48,020 | +15.2% | 0.18% | +24.5% |
| FOMX | Foamix Pharmaceuticals Ltd.shares | $4,661,000 | -2.3% | 930,398 | 0.0% | 0.18% | -4.8% | |
| UTHR | United Therapeutics Corporationclass b | $4,669,000 | +0.7% | 41,261 | 0.0% | 0.18% | -1.7% | |
| NTLA | Intellia Therapeutics, Inc. | $4,580,000 | +29.7% | 167,381 | 0.0% | 0.17% | +27.0% | |
| VRX | Bausch Health Companies Inc. | $4,462,000 | +46.0% | 192,000 | 0.0% | 0.17% | +42.0% | |
| ALBO | Albireo Pharma, Inc. | $4,438,000 | +9.0% | 125,000 | 0.0% | 0.17% | +6.3% | |
| ARRY | Buy | Array BioPharma Inc. | $4,297,000 | +68.7% | 256,056 | +64.1% | 0.16% | +64.6% |
| NVRO | Nevro Corp. | $4,231,000 | -7.9% | 52,990 | 0.0% | 0.16% | -10.1% | |
| TSRO | Buy | TESARO, Inc. | $4,223,000 | +28.3% | 94,970 | +64.9% | 0.16% | +25.0% |
| OVID | Ovid Therapeutics Inc. | $4,179,000 | +10.3% | 535,824 | 0.0% | 0.16% | +8.2% | |
| ARNA | Buy | Arena Pharmaceuticals, Inc. | $4,088,000 | +514.7% | 93,767 | +457.2% | 0.16% | +496.2% |
| SNR | Sell | New Senior Investment Group Inc. | $4,004,000 | -44.6% | 528,919 | -40.2% | 0.15% | -45.9% |
| VRNA | Verona Pharma plcsponsored adr | $3,781,000 | -31.3% | 275,000 | 0.0% | 0.14% | -33.2% | |
| IONS | Sell | Ionis Pharmaceuticals, Inc. | $3,452,000 | -52.7% | 82,838 | -50.0% | 0.13% | -53.9% |
| CLVS | Clovis Oncology, Inc. | $3,428,000 | -13.9% | 75,400 | 0.0% | 0.13% | -16.1% | |
| PTLA | Portola Pharmaceuticals, Inc. | $3,398,000 | +15.6% | 89,978 | 0.0% | 0.13% | +13.2% | |
| CHRS | Buy | Coherus Biosciences, Inc. | $3,372,000 | +68.6% | 240,843 | +33.0% | 0.13% | +64.1% |
| ARGX | argenx SEsponsored adr | $3,226,000 | +3.0% | 38,931 | 0.0% | 0.12% | 0.0% | |
| ARPO | New | Aerpio Pharmaceuticals, Inc. | $3,175,000 | – | 765,000 | +100.0% | 0.12% | – |
| TLGT | Buy | Teligent, Inc. | $3,136,000 | +69.2% | 906,362 | +64.4% | 0.12% | +65.3% |
| ZTS | New | Zoetis, Inc.class a | $3,046,000 | – | 35,760 | +100.0% | 0.12% | – |
| TTPH | Tetraphase Pharmaceuticals, Inc. | $3,068,000 | +16.3% | 859,322 | 0.0% | 0.12% | +12.6% | |
| PRAH | PRA Health Sciences, Inc. | $3,030,000 | +12.5% | 32,460 | 0.0% | 0.12% | +9.5% | |
| VAR | Buy | Varian Medical Systems, Inc. | $2,983,000 | +380.4% | 26,227 | +417.8% | 0.11% | +370.8% |
| ASND | Buy | Ascendis Pharma A/Ssponsored adr | $2,921,000 | +619.5% | 43,914 | +606.7% | 0.11% | +593.8% |
| WELL | Buy | Welltower Inc. | $2,856,000 | +145.2% | 45,560 | +112.9% | 0.11% | +140.0% |
| Trillium Therapeutics Inc. | $2,810,000 | -16.7% | 468,399 | 0.0% | 0.11% | -18.3% | ||
| PRGO | Perrigo Company plcshares | $2,720,000 | -12.5% | 37,300 | 0.0% | 0.10% | -14.9% | |
| AFMD | Sell | Affimed N.V. | $2,681,000 | -19.7% | 1,624,792 | -10.0% | 0.10% | -21.5% |
| HZNP | Horizon Pharma plcshares | $2,698,000 | +16.6% | 162,900 | 0.0% | 0.10% | +13.3% | |
| GBT | Sell | Global Blood Therapeutics, Inc. | $2,684,000 | -57.2% | 59,390 | -54.3% | 0.10% | -58.2% |
| AKBA | Buy | Akebia Therapeutics, Inc. | $2,661,000 | +110.2% | 266,612 | +100.7% | 0.10% | +106.1% |
| EVH | Evolent Health, Inc.class a | $2,579,000 | +47.7% | 122,500 | 0.0% | 0.10% | +44.1% | |
| CRL | Charles River Laboratories International, Inc. | $2,545,000 | +5.2% | 22,670 | 0.0% | 0.10% | +3.2% | |
| Egalet Corporationnote 5.50% 4/1/20 | $2,445,000 | -5.5% | 7,000,000 | 0.0% | 0.09% | -7.9% | ||
| ARDX | Ardelyx, Inc. | $2,366,000 | -26.7% | 639,370 | 0.0% | 0.09% | -28.6% | |
| STE | Buy | STERIS plcshares | $2,353,000 | +51.7% | 22,403 | +34.9% | 0.09% | +48.3% |
| CBAY | CymaBay Therapeutics, Inc. | $2,281,000 | +3.3% | 169,962 | 0.0% | 0.09% | +1.2% | |
| HSIC | Henry Schein, Inc. | $2,281,000 | +8.1% | 31,400 | 0.0% | 0.09% | +6.1% | |
| INVA | Innoviva, Inc. | $2,230,000 | -17.2% | 161,603 | 0.0% | 0.08% | -19.0% | |
| RARX | Sell | Ra Pharmaceuticals, Inc. | $2,189,000 | +21.7% | 219,952 | -35.0% | 0.08% | +18.6% |
| DERM | Dermira, Inc. | $2,155,000 | +15.2% | 234,200 | 0.0% | 0.08% | +12.3% | |
| RVNC | Buy | Revance Therapeutics, Inc. | $2,139,000 | +60.2% | 77,919 | +79.8% | 0.08% | +55.8% |
| HR | Healthcare Realty Trust Incorporated | $1,977,000 | +4.9% | 68,000 | 0.0% | 0.08% | +2.7% | |
| ONCE | Spark Therapeutics, Inc. | $1,825,000 | +24.3% | 22,046 | 0.0% | 0.07% | +21.1% | |
| LOXO | New | Loxo Oncology, Inc. | $1,798,000 | – | 10,365 | +100.0% | 0.07% | – |
| ACHN | Achillion Pharmaceuticals, Inc. | $1,743,000 | -23.7% | 616,000 | 0.0% | 0.07% | -25.8% | |
| SGMO | New | Sangamo Therapeutics, Inc. | $1,711,000 | – | 120,512 | +100.0% | 0.06% | – |
| TFX | Buy | Teleflex Incorporated | $1,711,000 | +170.3% | 6,379 | +157.0% | 0.06% | +160.0% |
| SNN | Smith & Nephew plcsponsored adr | $1,657,000 | -1.6% | 44,148 | 0.0% | 0.06% | -3.1% | |
| ACIU | AC Immune SAshares | $1,598,000 | -10.1% | 171,813 | 0.0% | 0.06% | -11.6% | |
| ZGNX | New | Zogenix, Inc. | $1,563,000 | – | 35,352 | +100.0% | 0.06% | – |
| XENE | Sell | Xenon Pharmaceuticals Inc. | $1,507,000 | +9.8% | 163,819 | -41.5% | 0.06% | +7.5% |
| PTGX | Protagonist Therapeutics, Inc. | $1,472,000 | -21.8% | 219,042 | 0.0% | 0.06% | -23.3% | |
| TXMD | Sell | TherapeuticsMD, Inc. | $1,463,000 | -35.9% | 234,384 | -50.0% | 0.06% | -37.1% |
| AMRN | Amarin Corporation plcsponsored adr | $1,477,000 | +2.6% | 478,149 | 0.0% | 0.06% | 0.0% | |
| QURE | Sell | uniQure N.V.shares | $1,427,000 | -69.6% | 37,741 | -81.1% | 0.05% | -70.5% |
| ACAD | ACADIA Pharmaceuticals Inc. | $1,431,000 | -32.0% | 93,689 | 0.0% | 0.05% | -34.1% | |
| SNDX | Syndax Pharmaceuticals, Inc. | $1,404,000 | -50.7% | 200,000 | 0.0% | 0.05% | -52.3% | |
| HTA | Healthcare Trust of America, Inc.class a | $1,240,000 | +1.9% | 46,000 | 0.0% | 0.05% | 0.0% | |
| HCP | HCP, Inc. | $1,175,000 | +11.2% | 45,500 | 0.0% | 0.04% | +9.8% | |
| MNKKQ | Mallinckrodt plcshares | $1,155,000 | +28.9% | 61,900 | 0.0% | 0.04% | +25.7% | |
| NSTG | NanoString Technologies, Inc. | $1,016,000 | +82.1% | 74,250 | 0.0% | 0.04% | +77.3% | |
| NUVA | New | NuVasive, Inc. | $1,021,000 | – | 19,580 | +100.0% | 0.04% | – |
| NLNK | NewLink Genetics Corporation | $976,000 | -34.3% | 205,026 | 0.0% | 0.04% | -36.2% | |
| CLSD | New | Clearside Biomedical, Inc. | $884,000 | – | 82,665 | +100.0% | 0.03% | – |
| LMAT | New | LeMaitre Vascular, Inc. | $909,000 | – | 27,150 | +100.0% | 0.03% | – |
| CDTX | Cidara Therapeutics, Inc. | $826,000 | +30.1% | 158,784 | 0.0% | 0.03% | +24.0% | |
| HOLX | Hologic, Inc. | $777,000 | +6.4% | 19,546 | 0.0% | 0.03% | +3.6% | |
| MTEM | Buy | Molecular Templates, Inc. | $754,000 | +78.3% | 144,110 | +172.5% | 0.03% | +81.2% |
| NVAX | Novavax, Inc. | $765,000 | -36.2% | 571,000 | 0.0% | 0.03% | -38.3% | |
| CYH | Community Health Systems, Inc. | $677,000 | -16.2% | 203,935 | 0.0% | 0.03% | -16.1% | |
| GMRE | Global Medical REIT Inc. | $650,000 | +27.5% | 73,400 | 0.0% | 0.02% | +25.0% | |
| LIVN | New | LivaNova PLC | $628,000 | – | 6,287 | +100.0% | 0.02% | – |
| RMR | The RMR Group Inc.class a | $584,000 | +12.3% | 7,441 | 0.0% | 0.02% | +10.0% | |
| BLCM | Bellicum Pharmaceuticals, Inc. | $443,000 | +12.4% | 60,000 | 0.0% | 0.02% | +13.3% | |
| ABIO | ARCA biopharma, Inc. | $451,000 | +11.4% | 811,227 | 0.0% | 0.02% | +6.2% | |
| DEPO | New | Depomed, Inc. | $420,000 | – | 62,973 | +100.0% | 0.02% | – |
| IOVA | New | Iovance Biotherapeutics, Inc. | $427,000 | – | 33,395 | +100.0% | 0.02% | – |
| ALQA | Alliqua BioMedical, Inc. | $338,000 | +6.3% | 165,000 | 0.0% | 0.01% | +8.3% | |
| CAH | Cardinal Health, Inc. | $308,000 | -22.0% | 6,300 | 0.0% | 0.01% | -20.0% | |
| AGIO | Agios Pharmaceuticals, Inc. | $237,000 | +3.0% | 2,810 | 0.0% | 0.01% | 0.0% | |
| NCNA | Sell | NuCana plc | $187,000 | -59.7% | 9,823 | -60.0% | 0.01% | -61.1% |
| TBPH | Theravance Biopharma, Inc. | $183,000 | -6.6% | 8,083 | 0.0% | 0.01% | -12.5% | |
| QHCCQ | Quorum Health Corporation | $119,000 | -38.7% | 23,725 | 0.0% | 0.01% | -37.5% | |
| JNCE | Jounce Therapeutics, Inc. | $78,000 | -65.5% | 10,127 | 0.0% | 0.00% | -66.7% | |
| CLDX | Celldex Therapeutics, Inc. | $53,000 | -78.5% | 105,800 | 0.0% | 0.00% | -80.0% | |
| NTUS | Exit | Natus Medical Incorporated | $0 | – | -11,335 | -100.0% | -0.02% | – |
| ADMS | Exit | Adamas Pharmaceuticals, Inc. | $0 | – | -16,699 | -100.0% | -0.02% | – |
| EIGR | Exit | Eiger BioPharmaceuticals, Inc. | $0 | – | -45,854 | -100.0% | -0.02% | – |
| FMI | Exit | Foundation Medicine, Inc. | $0 | – | -6,353 | -100.0% | -0.02% | – |
| XNCR | Exit | Xencor, Inc. | $0 | – | -20,000 | -100.0% | -0.02% | – |
| PTCT | Exit | PTC Therapeutics, Inc. | $0 | – | -24,299 | -100.0% | -0.03% | – |
| NTRA | Exit | Natera, Inc. | $0 | – | -103,731 | -100.0% | -0.04% | – |
| CYTK | Exit | Cytokinetics, Incorporated | $0 | – | -137,797 | -100.0% | -0.04% | – |
| GKOS | Exit | Glaukos Corporation | $0 | – | -55,079 | -100.0% | -0.07% | – |
| ABMD | Exit | ABIOMED, Inc. | $0 | – | -6,514 | -100.0% | -0.07% | – |
| LXRX | Exit | Lexicon Pharmaceuticals, Inc. | $0 | – | -231,054 | -100.0% | -0.08% | – |
| QTNT | Exit | Quotient Limitedshares | $0 | – | -442,461 | -100.0% | -0.08% | – |
| PHG | Exit | Koninklijke Philips N.V.ny registry shares | $0 | – | -75,335 | -100.0% | -0.11% | – |
| MYOV | Exit | Myovant Sciences Ltd. | $0 | – | -150,471 | -100.0% | -0.12% | – |
| ALDR | Exit | Alder Biopharmaceuticals, Inc. | $0 | – | -279,950 | -100.0% | -0.14% | – |
| BHVN | Exit | Biohaven Pharmaceutical Holding Company Ltd. | $0 | – | -162,477 | -100.0% | -0.16% | – |
| CTMX | Exit | CytomX Therapeutics, Inc. | $0 | – | -265,045 | -100.0% | -0.29% | – |
| AVXS | Exit | AveXis, Inc. | $0 | – | -70,347 | -100.0% | -0.34% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2018-08-13
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.