$2.52 Billion is the total value of Tekla Capital Management LLC's 116 reported holdings in Q1 2015. The portfolio turnover from Q4 2014 to Q1 2015 was 52.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CELG | Celgene Corporation | $229,964,000 | +3.1% | 1,994,834 | 0.0% | 9.11% | -12.8% | |
| GILD | Buy | Gilead Sciences, Inc. | $223,710,000 | +14.1% | 2,279,731 | +9.6% | 8.86% | -3.5% |
| BIIB | Buy | Biogen Idec, Inc. | $143,343,000 | +29.0% | 339,483 | +3.7% | 5.68% | +9.2% |
| B108PS | Buy | Actavis plcshares | $107,645,000 | +50.6% | 361,686 | +30.3% | 4.26% | +27.5% |
| ALXN | Buy | Alexion Pharmaceuticals, Inc. | $87,049,000 | -1.4% | 502,305 | +5.3% | 3.45% | -16.5% |
| INCY | Incyte Corporation | $85,836,000 | +25.4% | 936,461 | 0.0% | 3.40% | +6.1% | |
| REGN | Sell | Regeneron Pharmaceuticals, Inc. | $84,502,000 | +3.8% | 187,166 | -5.6% | 3.35% | -12.1% |
| BMRN | Sell | BioMarin Pharmaceutical Inc. | $66,669,000 | +29.4% | 534,977 | -6.1% | 2.64% | +9.5% |
| ABBV | Buy | AbbVie Inc. | $65,015,000 | +67.2% | 1,110,614 | +86.9% | 2.58% | +41.5% |
| TEVA | Buy | Teva Pharmaceutical Industries Ltd.adr | $62,150,000 | +155.1% | 997,594 | +135.5% | 2.46% | +116.1% |
| MYL | New | Mylan NVshares euro | $59,950,000 | – | 1,010,105 | +100.0% | 2.38% | – |
| PFE | Pfizer, Inc. | $56,994,000 | +11.7% | 1,638,241 | 0.0% | 2.26% | -5.5% | |
| AMGN | Sell | Amgen, Inc. | $56,232,000 | -7.2% | 351,779 | -7.5% | 2.23% | -21.4% |
| VRTX | Sell | Vertex Pharmaceuticals, Inc. | $54,767,000 | -34.3% | 464,244 | -33.9% | 2.17% | -44.4% |
| JNJ | Buy | Johnson & Johnson | $43,722,000 | +27.8% | 434,612 | +32.8% | 1.73% | +8.1% |
| GILD | Buy | Gilead Sciences, Inc.call | $42,206,000 | +46280.2% | 430,100 | +44655.5% | 1.67% | +41700.0% |
| AKRXQ | Akorn, Inc. | $40,359,000 | +31.2% | 849,482 | 0.0% | 1.60% | +11.1% | |
| ALKS | Buy | Alkermes plcshares | $35,879,000 | +40.2% | 588,470 | +34.7% | 1.42% | +18.7% |
| AET | Aetna, Inc. | $35,361,000 | +19.9% | 331,931 | 0.0% | 1.40% | +1.5% | |
| BMY | Bristol-Myers Squibb Co. | $34,523,000 | +9.3% | 535,240 | 0.0% | 1.37% | -7.5% | |
| CTRX | Catamaran Corporation | $25,817,000 | +15.1% | 433,600 | 0.0% | 1.02% | -2.6% | |
| ILMN | Buy | Illumina, Inc. | $24,735,000 | +29.0% | 133,241 | +28.3% | 0.98% | +9.3% |
| MOH | Molina Healthcare, Inc. | $23,410,000 | +25.7% | 347,901 | 0.0% | 0.93% | +6.4% | |
| ACOR | Buy | Acorda Therapeutics, Inc. | $22,659,000 | +103.0% | 680,862 | +149.3% | 0.90% | +71.7% |
| ENDP | Endo International PLCshares | $22,584,000 | +24.4% | 251,773 | 0.0% | 0.90% | +5.3% | |
| BAX | New | Baxter International, Inc. | $21,893,000 | – | 319,600 | +100.0% | 0.87% | – |
| PRGO | Buy | Perrigo Company plcshares | $21,629,000 | +105.5% | 130,652 | +107.5% | 0.86% | +73.8% |
| VTR | Ventas Inc. | $21,379,000 | +1.8% | 292,782 | 0.0% | 0.85% | -13.8% | |
| MDRX | Buy | Allscripts Healthcare Solutions, Inc. | $21,267,000 | +3.8% | 1,778,200 | +10.8% | 0.84% | -12.1% |
| JAZZ | Sell | Jazz Pharmaceuticals plcshares | $20,863,000 | -36.7% | 120,741 | -40.0% | 0.83% | -46.4% |
| RCPT | Buy | Receptos, Inc. | $20,578,000 | +723.4% | 124,800 | +511.8% | 0.82% | +596.6% |
| NBIX | Sell | Neurocrine Biosciences, Inc. | $19,901,000 | -10.9% | 501,150 | -49.9% | 0.79% | -24.6% |
| IBB | Ishares Nasdaq Biotechnology ETFetf | $19,806,000 | +13.2% | 57,670 | 0.0% | 0.78% | -4.2% | |
| GEVA | Sell | Synageva BioPharma Corp | $19,378,000 | -6.4% | 198,689 | -10.9% | 0.77% | -20.7% |
| TMO | Buy | Thermo Fisher Scientific Inc. | $19,035,000 | +25.6% | 141,695 | +17.1% | 0.75% | +6.2% |
| DOC | Buy | Physicians Realty Trust | $18,506,000 | +16.4% | 1,050,902 | +9.7% | 0.73% | -1.5% |
| MPW | Buy | Medical Properties Trust Inc. | $17,004,000 | +26.1% | 1,153,574 | +17.9% | 0.67% | +6.8% |
| OHI | Buy | Omega Healthcare Investors Inc. | $16,760,000 | +14.0% | 413,116 | +9.7% | 0.66% | -3.5% |
| IPXL | Impax Laboratories, Inc. | $16,155,000 | +47.9% | 344,683 | 0.0% | 0.64% | +25.2% | |
| Corsicanto Ltd.note 3.5% 1/15/32 | $15,656,000 | +71.4% | 14,700,000 | 0.0% | 0.62% | +45.2% | ||
| MCK | McKesson Corporation | $15,350,000 | +9.0% | 67,862 | 0.0% | 0.61% | -7.7% | |
| SBRA | Buy | Sabra Health Care REIT Inc. | $15,123,000 | +22.1% | 456,190 | +11.8% | 0.60% | +3.3% |
| KPTI | Buy | Karyopharm Therapeutics Inc. | $14,600,000 | +183.1% | 476,966 | +246.2% | 0.58% | +140.2% |
| ALR | Alere, Inc. | $14,567,000 | +28.7% | 297,901 | 0.0% | 0.58% | +8.9% | |
| ALNY | Buy | Alnylam Pharmaceuticals, Inc. | $13,595,000 | +127.5% | 130,195 | +111.4% | 0.54% | +92.5% |
| HCNPRI | New | Health Care REIT Inc. | $13,432,000 | – | 200,000 | +100.0% | 0.53% | – |
| ALXN | New | Alexion Pharmaceuticals, Inc.call | $13,379,000 | – | 77,200 | +100.0% | 0.53% | – |
| HRTX | Heron Therapeutics, Inc. | $12,716,000 | +44.6% | 873,940 | 0.0% | 0.50% | +22.3% | |
| VSTM | Buy | Verastem, Inc. | $12,711,000 | +21.0% | 1,249,827 | +8.7% | 0.50% | +2.4% |
| IRWD | Ironwood Pharmaceuticals, Inc. | $12,289,000 | +4.4% | 768,050 | 0.0% | 0.49% | -11.6% | |
| ZBH | Buy | Zimmer Holdings, Inc. | $12,022,000 | +32.8% | 102,300 | +28.2% | 0.48% | +12.3% |
| ABBV | New | AbbVie Inc.call | $11,708,000 | – | 200,000 | +100.0% | 0.46% | – |
| SYK | Buy | Stryker Corporation | $11,433,000 | +26.5% | 123,940 | +29.3% | 0.45% | +7.1% |
| PRGO | New | Perrigo Company plccall | $11,208,000 | – | 67,700 | +100.0% | 0.44% | – |
| HCA | HCA Holdings, Inc. | $11,096,000 | +2.5% | 147,488 | 0.0% | 0.44% | -13.2% | |
| CYH | Buy | Community Health Systems, Inc. | $10,956,000 | +31.4% | 209,572 | +35.5% | 0.43% | +11.3% |
| LTC | LTC Properties Inc. | $10,884,000 | +6.5% | 236,618 | 0.0% | 0.43% | -9.8% | |
| SNH | Buy | Senior Housing Properties Trustshares | $10,642,000 | +17.5% | 479,604 | +17.1% | 0.42% | -0.5% |
| SGMO | Sangamo BioSciences, Inc. | $10,648,000 | +3.1% | 679,100 | 0.0% | 0.42% | -12.6% | |
| MRK | New | Merck & Co., Inc. | $10,634,000 | – | 185,000 | +100.0% | 0.42% | – |
| STJ | Buy | St Jude Medical, Inc. | $10,563,000 | +32.6% | 161,510 | +31.8% | 0.42% | +12.3% |
| CI | Cigna Corp | $9,611,000 | +25.8% | 74,251 | 0.0% | 0.38% | +6.4% | |
| SGNT | Buy | Sagent Pharmaceuticals, Inc. | $9,521,000 | +343.5% | 409,500 | +378.9% | 0.38% | +277.0% |
| AGIO | Buy | Agios Pharmaceuticals, Inc. | $9,458,000 | +82.7% | 100,300 | +117.1% | 0.38% | +55.0% |
| ELGX | Endologix Inc. | $9,406,000 | +11.6% | 551,000 | 0.0% | 0.37% | -5.3% | |
| TXMD | New | TherapeuticsMD, Inc. | $8,963,000 | – | 1,481,500 | +100.0% | 0.36% | – |
| IDXX | IDEXX Laboratories, Inc. | $8,692,000 | +4.2% | 56,265 | 0.0% | 0.34% | -11.8% | |
| CNC | Buy | Centene Corporation | $8,483,000 | +36.1% | 120,000 | +100.0% | 0.34% | +15.1% |
| WCG | WellCare Health Plans Inc. | $8,108,000 | +11.5% | 88,652 | 0.0% | 0.32% | -5.9% | |
| GEVA | New | Synageva BioPharma Corpcall | $6,925,000 | – | 71,000 | +100.0% | 0.27% | – |
| ARAY | Accuray, Inc. | $6,807,000 | +23.2% | 731,943 | 0.0% | 0.27% | +4.2% | |
| MACK | Merrimack Pharmaceuticals, Inc. | $6,745,000 | +5.1% | 567,787 | 0.0% | 0.27% | -11.0% | |
| BLUE | bluebird bio, Inc. | $6,585,000 | +31.7% | 54,527 | 0.0% | 0.26% | +11.5% | |
| INFI | Infinity Pharmaceuticals, Inc. | $6,132,000 | -17.2% | 438,623 | 0.0% | 0.24% | -30.0% | |
| ALNY | New | Alnylam Pharmaceuticals, Inc.call | $5,670,000 | – | 54,300 | +100.0% | 0.22% | – |
| ILMN | New | Illumina, Inc.call | $5,458,000 | – | 29,400 | +100.0% | 0.22% | – |
| AEGR | New | Aegerion Pharmaceuticals, Inc. | $5,391,000 | – | 206,000 | +100.0% | 0.21% | – |
| ACHN | New | Achillion Pharmaceuticals Inc.call | $5,396,000 | – | 547,300 | +100.0% | 0.21% | – |
| ACHN | New | Achillion Pharmaceuticals Inc. | $5,396,000 | – | 547,300 | +100.0% | 0.21% | – |
| MNTA | Sell | Momenta Pharmaceuticals, Inc. | $5,374,000 | -58.2% | 353,575 | -66.9% | 0.21% | -64.6% |
| BIIB | New | Biogen Idec, Inc.call | $5,151,000 | – | 12,200 | +100.0% | 0.20% | – |
| INCY | New | Incyte Corporationcall | $5,133,000 | – | 56,000 | +100.0% | 0.20% | – |
| ACTPRA | New | Actavis plcpreferred convertible series a | $5,060,000 | – | 5,000 | +100.0% | 0.20% | – |
| Supernus Pharmaceuticals, Inc.note 7.50% 5/1/19 | $4,826,000 | +38.3% | 2,000,000 | 0.0% | 0.19% | +17.2% | ||
| FLKS | New | Flex Pharma, Inc. | $4,559,000 | – | 232,600 | +100.0% | 0.18% | – |
| New | Spectrum Pharmaceuticals, Inc.note 2.75% 12/15/18 | $4,572,000 | – | 5,000,000 | +100.0% | 0.18% | – | |
| TROV | New | TrovaGene, Inc. | $4,427,000 | – | 650,000 | +100.0% | 0.18% | – |
| T107PS | Wright Medical Group Inc. | $4,027,000 | -4.0% | 156,100 | 0.0% | 0.16% | -18.4% | |
| ZGNX | New | Zogenix, Inc. | $3,906,000 | – | 2,850,811 | +100.0% | 0.16% | – |
| IPCI | Sell | IntelliPharmaCeutics International Inc. | $3,889,000 | +22.6% | 1,394,000 | -0.7% | 0.15% | +3.4% |
| EPZM | New | Epizyme, Inc. | $3,756,000 | – | 200,000 | +100.0% | 0.15% | – |
| ITCI | New | Intra-Cellular Therapies, Inc. | $3,582,000 | – | 150,000 | +100.0% | 0.14% | – |
| AXDX | New | Accelerate Diagnostics, Inc | $3,254,000 | – | 144,625 | +100.0% | 0.13% | – |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $3,058,000 | -38.8% | 230,300 | -33.3% | 0.12% | -48.3% |
| THC | New | Tenet Healthcare Corp | $2,946,000 | – | 59,500 | +100.0% | 0.12% | – |
| Merrimack Pharmaceuticals, Inc.note 4.50% 7/15/20 | $2,929,000 | +3.4% | 1,485,000 | 0.0% | 0.12% | -12.8% | ||
| KYTH | Sell | KYTHERA Biopharmaceuticals Inc | $2,794,000 | -27.7% | 55,717 | -50.0% | 0.11% | -38.7% |
| ATHN | New | Athenahealth, Inc.call | $2,758,000 | – | 23,100 | +100.0% | 0.11% | – |
| ATHN | New | Athenahealth, Inc. | $2,758,000 | – | 23,100 | +100.0% | 0.11% | – |
| KITE | New | Kite Pharma, Inc.call | $2,682,000 | – | 46,500 | +100.0% | 0.11% | – |
| KITE | New | Kite Pharma, Inc. | $2,682,000 | – | 46,500 | +100.0% | 0.11% | – |
| MYGN | Sell | Myriad Genetics, Inc. | $2,648,000 | -30.7% | 74,800 | -33.3% | 0.10% | -41.3% |
| MYGN | New | Myriad Genetics, Inc.call | $2,648,000 | – | 74,800 | +100.0% | 0.10% | – |
| CYH | New | Community Health Systems, Inc.call | $2,614,000 | – | 50,000 | +100.0% | 0.10% | – |
| BDSI | Sell | BioDelivery Sciences International, Inc. | $2,625,000 | -23.0% | 250,000 | -11.8% | 0.10% | -34.6% |
| IMMU | New | Immunomedics, Inc. | $1,915,000 | – | 500,000 | +100.0% | 0.08% | – |
| EBIO | Sell | Eleven Biotherapeutics, Inc. | $1,748,000 | -73.2% | 195,964 | -67.9% | 0.07% | -77.4% |
| SRNE | Sell | Sorrento Therapeutics, Inc. | $1,648,000 | -23.5% | 142,597 | -33.3% | 0.06% | -35.6% |
| SRPT | New | Sarepta Therapeutics, Inc.call | $1,529,000 | – | 115,100 | +100.0% | 0.06% | – |
| CLLS | New | Cellectis S.A.sponsored ads | $1,384,000 | – | 40,000 | +100.0% | 0.06% | – |
| BLCM | Bellicum Pharmaceuticals, Inc. | $1,390,000 | +0.6% | 60,000 | 0.0% | 0.06% | -15.4% | |
| SAGE | Buy | Sage Therapeutics, Inc. | $753,000 | +311.5% | 15,000 | +200.0% | 0.03% | +233.3% |
| ZFGN | Sell | Zafgen, Inc. | $527,000 | -35.8% | 13,307 | -50.0% | 0.02% | -44.7% |
| MGNX | Macrogenics, Inc. | $400,000 | -10.5% | 12,743 | 0.0% | 0.02% | -23.8% | |
| XNCR | New | Xencor, Inc. | $306,000 | – | 20,000 | +100.0% | 0.01% | – |
| OGXI | OncoGenex Pharmaceuticals, Inc. | $243,000 | -6.2% | 113,100 | 0.0% | 0.01% | -16.7% | |
| CLVS | Exit | Clovis Oncology, Inc. | $0 | – | -51 | -100.0% | 0.00% | – |
| AMGN | Exit | Amgen Inc.call | $0 | – | -285 | -100.0% | -0.00% | – |
| REGN | Exit | Regeneron Pharmaceuticals, Inc.call | $0 | – | -112 | -100.0% | -0.00% | – |
| JAZZ | Exit | Jazz Pharmaceuticals plccall | $0 | – | -281 | -100.0% | -0.00% | – |
| MEIP | Exit | MEI Pharma, Inc. | $0 | – | -243,920 | -100.0% | -0.05% | – |
| DRNA | Exit | Dicerna Pharmaceuticals, Inc. | $0 | – | -156,250 | -100.0% | -0.12% | – |
| LGND | Exit | Ligand Pharmaceuticals Inc. | $0 | – | -69,200 | -100.0% | -0.17% | – |
| PTCT | Exit | PTC Therapeutics, Inc. | $0 | – | -119,150 | -100.0% | -0.29% | – |
| CLDN | Exit | Celladon Corporation | $0 | – | -606,482 | -100.0% | -0.55% | – |
| LLY | Exit | Eli Lilly & Co | $0 | – | -186,918 | -100.0% | -0.60% | – |
| HCNPRI | Exit | Health Care REIT Inc.convertible preferred | $0 | – | -200,000 | -100.0% | -0.62% | – |
| P103PS | Exit | NPS Pharmaceuticals, Inc. | $0 | – | -625,900 | -100.0% | -1.05% | – |
| AGN | Exit | Allergan, Inc. | $0 | – | -228,227 | -100.0% | -2.27% | – |
| MYL | Exit | Mylan, Inc. | $0 | – | -1,010,105 | -100.0% | -2.66% | – |
| SHPG | Exit | Shire plcsponsored adr | $0 | – | -281,522 | -100.0% | -2.80% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2015-05-06
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.