Baker Brothers Advisors - Q1 2017 holdings

$12.2 Billion is the total value of Baker Brothers Advisors's 119 reported holdings in Q1 2017. The portfolio turnover from Q4 2016 to Q1 2017 was 19.5% .

 Value Shares↓ Weighting
INCY BuyIncyte Corporation$4,559,485,000
+93.5%
34,110,011
+45.2%
37.31%
+61.5%
SGEN BuySeattle Genetics, Inc.$2,873,680,000
+19.1%
45,715,556
+0.0%
23.52%
-0.6%
ACAD  ACADIA Pharmaceuticals Inc.$887,684,000
+19.2%
25,819,7680.0%7.26%
-0.5%
ALXN BuyAlexion Pharmaceuticals, Inc.$793,410,000
-0.9%
6,544,130
+0.0%
6.49%
-17.3%
GHDX BuyGenomic Health, Inc.$433,648,000
+7.2%
13,770,982
+0.0%
3.55%
-10.6%
BMRN  BioMarin Pharmaceutical Inc.$421,913,000
+6.0%
4,806,4830.0%3.45%
-11.6%
DBVT  DBV Technologies S.A.sponsored adr$194,047,000
+0.3%
5,509,5600.0%1.59%
-16.3%
AQXP BuyAquinox Pharmaceuticals, Inc.$182,491,000
+4.9%
10,934,154
+3.8%
1.49%
-12.4%
BGNE  BeiGene, Ltd.sponsored adr$134,475,000
+20.6%
3,673,1750.0%1.10%
+0.6%
AKAOQ  Achaogen, Inc.$115,613,000
+93.8%
4,582,3820.0%0.95%
+61.7%
BCRX BuyBioCryst Pharmaceuticals, Inc.$98,421,000
+41.8%
11,716,784
+6.9%
0.80%
+18.4%
 BioMarin Pharmaceutical Inc.note 1.875% 4/23/2017$95,967,000
+6.0%
22,379,0000.0%0.78%
-11.5%
AAAP BuyAdvanced Accelerator Applications S.A.sponsored ads$88,557,000
+52.7%
2,221,706
+2.5%
0.72%
+27.4%
NVTA  Invitae Corporation$80,609,000
+39.3%
7,288,3000.0%0.66%
+16.4%
AMRN BuyAmarin Corporation plcsponsored adr new$72,501,000
+6.2%
22,656,469
+2.2%
0.59%
-11.4%
ONCE  Spark Therapeutics, Inc.$70,320,000
+6.9%
1,318,3410.0%0.58%
-10.9%
ACOR  Acorda Therapeutics, Inc.$69,338,000
+11.7%
3,301,7910.0%0.57%
-6.9%
BLCM BuyBellicum Pharmaceuticals, Inc.$62,099,000
-6.3%
5,032,313
+3.4%
0.51%
-21.8%
CERS  Cerus Corporation$58,087,000
+2.3%
13,053,2750.0%0.48%
-14.7%
EXEL SellExelixis, Inc.$56,419,000
+26.0%
2,603,569
-13.3%
0.46%
+5.2%
NewNovavax, Inc.note 3.75% 2/1/2023 added$48,554,000108,500,000
+100.0%
0.40%
HRTX BuyHeron Therapeutics, Inc.$41,754,000
+33.7%
2,783,569
+16.8%
0.34%
+11.8%
NBIX  Neurocrine Biosciences, Inc.$38,772,000
+11.9%
895,4220.0%0.32%
-6.8%
AVXS BuyAveXis, Inc.$38,015,000
+152.6%
500,000
+58.6%
0.31%
+110.1%
ASND BuyAscendis Pharma A/Ssponsored adr$37,841,000
+82.7%
1,351,463
+32.1%
0.31%
+52.7%
VSAR SellVersartis, Inc.$35,454,000
+23.9%
1,660,593
-13.5%
0.29%
+3.2%
BLUE  bluebird bio, Inc.$31,946,000
+47.3%
351,4410.0%0.26%
+22.5%
PGNX  Progenics Pharmaceuticals, Inc.$29,744,000
+9.3%
3,150,8080.0%0.24%
-9.0%
 Acorda Therapeutics, Inc.note 1.75% 6/15/2021$29,696,000
+11.8%
35,083,0000.0%0.24%
-6.5%
MRUS  Merus N.V.$28,293,000
+15.5%
1,160,0140.0%0.23%
-3.3%
IDRA BuyIdera Pharmaceuticals, Inc.$25,408,000
+64.9%
10,286,483
+0.1%
0.21%
+37.7%
SGMO BuySangamo Therapeutics, Inc.$23,561,000
+90.5%
4,530,901
+11.7%
0.19%
+59.5%
GLPG  Galapagos NVsponsored adr$22,400,000
+34.3%
259,8940.0%0.18%
+11.6%
XNCR  Xencor, Inc.$20,860,000
-9.1%
872,0720.0%0.17%
-24.0%
HALO  Halozyme Therapeutics, Inc.$18,034,000
+31.2%
1,391,5070.0%0.15%
+9.6%
 NeuroDerm Ltd.$15,178,000
+19.6%
571,6670.0%0.12%0.0%
NTLA  Intellia Therapeutics, Inc.$14,965,000
+7.5%
1,062,1200.0%0.12%
-10.3%
SAGE  Sage Therapeutics, Inc.$14,806,000
+39.2%
208,3280.0%0.12%
+16.3%
AIMT  Aimmune Therapeutics, Inc.$14,644,000
+6.3%
673,9080.0%0.12%
-11.1%
DERM BuyDermira, Inc.$14,171,000
+43.1%
415,448
+27.3%
0.12%
+19.6%
ARRY SellArray BioPharma Inc.$14,178,000
-37.6%
1,585,913
-38.7%
0.12%
-48.0%
 BioMarin Pharmaceutical Inc.note 0.75% 10/15/2018$13,830,000
+0.7%
12,228,0000.0%0.11%
-16.3%
AERI  Aerie Pharmaceuticals, Inc.$13,576,000
+19.8%
299,3560.0%0.11%0.0%
SellAegerion Pharmaceuticals, Inc.note 2.0% 8/15/2019$13,241,000
-30.7%
16,517,000
-37.7%
0.11%
-42.2%
FOMX  Foamix Pharmaceuticals Ltd.$12,210,000
-55.4%
2,466,7020.0%0.10%
-62.7%
MRTX  Mirati Therapeutics, Inc.$11,800,000
+9.5%
2,269,1980.0%0.10%
-8.5%
IMGN  ImmunoGen, Inc.$11,669,000
+89.7%
3,015,3530.0%0.10%
+58.3%
LJPC BuyLa Jolla Pharmaceutical Company$11,317,000
+4595.9%
379,134
+2658.1%
0.09%
+4550.0%
CPRX  Catalyst Pharmaceuticals, Inc.$9,949,000
+85.7%
5,102,1530.0%0.08%
+52.8%
ITCI  Intra-Cellular Therapies, Inc.$9,899,000
+7.7%
609,1660.0%0.08%
-10.0%
ALKS  Alkermes plc$8,790,000
+5.3%
150,2510.0%0.07%
-12.2%
ABEO  Abeona Therapeutics Inc.$8,422,000
+3.1%
1,684,3640.0%0.07%
-13.8%
RIGL BuyRigel Pharmaceuticals, Inc.$8,337,000
+73.5%
2,518,882
+24.8%
0.07%
+44.7%
ACHN  Achillion Pharmaceuticals, Inc.$7,816,000
+1.9%
1,856,6370.0%0.06%
-14.7%
LGND  Ligand Pharmaceuticals Incorporated$7,767,000
+4.2%
73,3860.0%0.06%
-12.3%
AGIO  Agios Pharmaceuticals, Inc.$7,514,000
+40.0%
128,6660.0%0.06%
+15.1%
CFRX  ContraFect Corporation$7,283,000
+2.9%
4,045,8760.0%0.06%
-13.0%
INSM  Insmed Incorporated$7,004,000
+32.4%
400,0000.0%0.06%
+9.6%
MGNX  MacroGenics, Inc.$6,764,000
-9.0%
363,6760.0%0.06%
-24.7%
ASMB  Assembly Biosciences, Inc.$6,373,000
+109.8%
250,0000.0%0.05%
+73.3%
CBAY BuyCymaBay Therapeutics, Inc.$6,078,000
+1036.1%
1,413,499
+357.0%
0.05%
+900.0%
LOXO  Loxo Oncology, Inc.$5,796,000
+31.0%
137,7350.0%0.05%
+9.3%
AKTX  Akari Therapeutics plcsponsored adr$5,501,000
+57.3%
496,9010.0%0.04%
+32.4%
STML BuyStemline Therapeutics, Inc.$5,416,000
+51.8%
633,497
+90.0%
0.04%
+25.7%
RXDX  Ignyta, Inc.$4,911,000
+62.3%
571,0000.0%0.04%
+33.3%
BIIB  Biogen Inc.$4,511,000
-3.6%
16,5000.0%0.04%
-19.6%
ALDR  Alder BioPharmaceuticals, Inc.$4,520,0000.0%217,3280.0%0.04%
-15.9%
 Array BioPharma Inc.note 3.0% 6/1/2020$4,258,000
+1.5%
3,000,0000.0%0.04%
-14.6%
ANAB NewAnaptysBio, Inc.$4,163,000150,000
+100.0%
0.03%
ZGNX SellZogenix, Inc.$4,144,000
-59.3%
381,939
-54.5%
0.03%
-66.0%
NBRV  Nabriva Therapeutics AGsponsored adr$4,200,000
+101.3%
350,0000.0%0.03%
+70.0%
EPZM  Epizyme, Inc.$3,987,000
+41.7%
232,4810.0%0.03%
+17.9%
RARX  Ra Pharmaceuticals, Inc.$3,789,000
+40.2%
177,9520.0%0.03%
+19.2%
RARE  Ultragenyx Pharmaceutical Inc.$3,389,000
-3.6%
50,0000.0%0.03%
-17.6%
SYRS  Syros Pharmaceuticals, Inc.$3,257,000
+31.0%
204,4650.0%0.03%
+12.5%
TRVN BuyTrevena, Inc.$3,146,000
+18.9%
857,206
+90.5%
0.03%0.0%
 Inotek Pharmaceuticals Corporationnote 5.75% 8/1/2021$3,008,000
-41.8%
5,000,0000.0%0.02%
-51.0%
ADMS  Adamas Pharmaceuticals, Inc.$3,021,000
+3.6%
172,6300.0%0.02%
-13.8%
GNMX BuyAevi Genomic Medicine, Inc.$3,010,000
-34.0%
1,618,089
+83.8%
0.02%
-44.4%
SNSS  Sunesis Pharmaceuticals, Inc.$3,041,000
+13.3%
741,6650.0%0.02%
-3.8%
KPTI  Karyopharm Therapeutics Inc.$2,786,000
+36.6%
216,9900.0%0.02%
+15.0%
 Protalix BioTherapeutics, Inc.note 4.5% 9/15/2018$2,543,000
+10.9%
3,423,0000.0%0.02%
-4.5%
 Trillium Therapeutics Inc.$2,544,000
+8.9%
413,6970.0%0.02%
-8.7%
SELB  Selecta Biosciences, Inc.$2,516,000
-16.5%
175,7120.0%0.02%
-30.0%
DMTX  Dimension Therapeutics, Inc.$2,191,000
-59.8%
1,251,8810.0%0.02%
-66.0%
JNCE NewJounce Therapeutics, Inc.$2,199,000100,000
+100.0%
0.02%
TNXP NewTonix Pharmaceuticals Holdings Corp.$2,099,000449,500
+100.0%
0.02%
NTRA SellNatera, Inc.$2,028,000
-30.5%
228,676
-8.3%
0.02%
-41.4%
GLYC  GlycoMimetics, Inc.$2,070,000
-11.0%
381,2350.0%0.02%
-26.1%
SBPH  Spring Bank Pharmaceuticals, Inc.$1,952,000
+11.4%
219,2980.0%0.02%
-5.9%
INFI  Infinity Pharmaceuticals, Inc.$1,875,000
+139.2%
580,4000.0%0.02%
+87.5%
NVIV  InVivo Therapeutics Holdings Corp.$1,620,000
-3.6%
400,0000.0%0.01%
-18.8%
AGLE SellAeglea BioTherapeutics, Inc.$1,415,000
-19.5%
189,987
-53.0%
0.01%
-29.4%
MCRB  Seres Therapeutics, Inc.$1,409,000
+13.8%
125,0000.0%0.01%0.0%
MDWD  MediWound Ltd.$1,492,000
+44.2%
226,0000.0%0.01%
+20.0%
MYOK  MyoKardia, Inc.$1,315,000
+1.5%
100,0000.0%0.01%
-15.4%
FLGT  Fulgent Genetics, Inc.$1,365,000
-5.6%
125,0000.0%0.01%
-21.4%
CLLS  Cellectis S.A.sponsored ads$1,200,000
+41.5%
50,0000.0%0.01%
+25.0%
CRBP SellCorbus Pharmaceuticals Holdings, Inc.$1,074,000
-51.1%
130,129
-50.0%
0.01%
-59.1%
JUNO SellJuno Therapeutics, Inc.$1,110,000
-26.4%
50,000
-37.5%
0.01%
-40.0%
AFMD  Affimed N.V.$920,000
+27.8%
400,0000.0%0.01%
+14.3%
IMDZ  Immune Design Corp.$1,013,000
+23.7%
148,9370.0%0.01%0.0%
MDGL  Madrigal Pharmaceuticals, Inc.$890,000
+3.4%
57,7620.0%0.01%
-12.5%
CMRX  Chimerix, Inc.$735,000
+38.7%
115,2160.0%0.01%
+20.0%
XLRN  Acceleron Pharma Inc.$761,000
+3.7%
28,7650.0%0.01%
-14.3%
FPRX  Five Prime Therapeutics, Inc.$696,000
-27.8%
19,2470.0%0.01%
-33.3%
ADAP  Adaptimmune Therapeutics plcsponsored adr$551,000
+36.0%
100,0000.0%0.01%
+25.0%
PTN  Palatin Technologies, Inc.$671,000
-35.2%
2,050,0000.0%0.01%
-50.0%
RTTR  Ritter Pharmaceuticals, Inc.$568,000
-47.6%
400,0000.0%0.01%
-54.5%
ABUS  Arbutus Biopharma Corporation$587,000
+32.8%
180,5820.0%0.01%
+25.0%
DVAX  Dynavax Technologies Corporation$446,000
+50.7%
75,0000.0%0.00%
+33.3%
PRTO SellProteon Therapeutics, Inc.$523,000
-29.3%
298,591
-23.3%
0.00%
-42.9%
BIVV NewBioverativ Inc.$449,0008,249
+100.0%
0.00%
CCXI  ChemoCentryx, Inc.$357,000
-1.7%
49,0640.0%0.00%
-25.0%
BDSI  BioDelivery Sciences International, Inc.$399,000
+8.4%
210,0210.0%0.00%
-25.0%
WINT  Windtree Therapeutics, Inc.$291,000
-8.8%
254,9730.0%0.00%
-33.3%
BPMX NewBioPharmX Corporation$191,000377,295
+100.0%
0.00%
CYCCP  Cyclacel Pharmaceuticals, Inc.pfd conv ex 6%$83,000
+1.2%
13,2530.0%0.00%0.0%
BTXWS  BioTime, Inc.*w exp 10/1/201$12,000
-14.3%
20,0840.0%0.00%
DNAI ExitProNAi Therapeutics, Inc.$0-200,000
-100.0%
-0.00%
ALNY ExitAlnylam Pharmaceuticals, Inc.$0-11,340
-100.0%
-0.00%
FMI ExitFoundation Medicine, Inc.$0-20,892
-100.0%
-0.00%
ExitAptose Biosciences Inc.$0-258,311
-100.0%
-0.00%
ALDX ExitAldeyra Therapeutics, Inc.$0-142,000
-100.0%
-0.01%
TENX ExitTenax Therapeutics, Inc.$0-420,000
-100.0%
-0.01%
PRQR ExitProQR Therapeutics N.V.$0-212,698
-100.0%
-0.01%
CLCD ExitColucid Pharmaceuticals, Inc.$0-30,310
-100.0%
-0.01%
QURE ExituniQure N.V.$0-230,000
-100.0%
-0.01%
CNCE ExitConcert Pharmaceuticals, Inc.$0-152,964
-100.0%
-0.02%
SCYX ExitSCYNEXIS, Inc.$0-467,600
-100.0%
-0.02%
OSIR ExitOsiris Therapeutics, Inc.$0-499,193
-100.0%
-0.02%
ENTA ExitEnanta Pharmaceuticals, Inc.$0-75,357
-100.0%
-0.02%
IONS ExitIonis Pharmaceuticals, Inc.$0-57,140
-100.0%
-0.03%
NERV ExitMinerva Neurosciences, Inc.$0-258,805
-100.0%
-0.03%
ADHD ExitAlcobra Ltd.$0-2,336,359
-100.0%
-0.05%
DSCI ExitDerma Sciences, Inc.$0-3,752,390
-100.0%
-0.19%
ABBV ExitAbbVie Inc.$0-1,685,994
-100.0%
-1.04%
ExitIncyte Corporationnote 0.375% 11/15/2018$0-259,000,000
-100.0%
-5.08%
ExitIncyte Corporationnote 1.25% 11/15/2020$0-274,500,000
-100.0%
-5.48%
Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR filed 2017-05-15
Signatures

The EDGAR filing(s) were signed by:

About Baker Brothers Advisors

Baker Brothers Advisors is a well-known investment management firm that specializes in the healthcare sector. The firm was founded in 2000 by brothers Julian and Felix Baker, who are both highly respected in the industry. Julian Baker is the CEO of the firm, while Felix Baker serves as a managing partner.

Baker Brothers Advisors has a reputation for investing in innovative healthcare companies that have the potential to make a significant impact on the industry. The firm has a long-term investment approach and is known for taking large positions in companies that it believes in. Some of the firm's most successful investments include companies such as Pharmacyclics, which was acquired by AbbVie for $21 billion, and Ariad Pharmaceuticals, which was acquired by Takeda for $5.2 billion.

The firm's investment strategy is led by its Chief Investment Officer, Dr. Robert Duggan, who has a background in both medicine and finance. Dr. Duggan is known for his ability to identify promising healthcare companies and for his willingness to take risks on early-stage companies.

Overall, Baker Brothers Advisors is a highly respected investment management firm that has a proven track record of success in the healthcare sector. While the firm's investment approach may not be suitable for all investors, those who are interested in the healthcare sector may want to consider Baker Brothers Advisors as a potential investment opportunity.

It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
Incyte Corporation42Q3 202337.6%
ACADIA Pharmaceuticals Inc.42Q3 202310.9%
Biomarin Pharmaceuticals Inc.42Q3 20235.9%
BioCryst Pharmaceuticals, Inc.42Q3 20231.7%
Cerus Corporation42Q3 20230.9%
Insmed Incorporated42Q3 20230.4%
Mirati Therapeutics, Inc.41Q3 20231.8%
Bluebird Bio Inc.41Q3 20230.3%
Heron Therapeutics, Inc.39Q3 20231.5%
ChemoCentryx, Inc.37Q3 20220.6%

View Baker Brothers Advisors's complete holdings history.

Latest significant ownerships (13-D/G)
Baker Brothers Advisors Q1 2017 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
Neoleukin Therapeutics, Inc.August 17, 20239,469,83820.0%
Mereo Biopharma Group plcAugust 10, 202314,604,3912.2%
Verastem, Inc.August 10, 2023? ?
TScan Therapeutics, Inc.June 02, 20232,793,9386.5%
ACADIA PHARMACEUTICALS INCMay 24, 202343,084,28026.5%
INCYTE CORPMarch 15, 202336,280,96716.3%
Seagen Inc.March 13, 202346,985,65625.1%
Talis Biomedical CorpMarch 10, 202337,569,14066.2%
Aeglea BioTherapeutics, Inc.February 14, 20236,384,0139.9%
Merus N.V.February 14, 2023? ?

View Baker Brothers Advisors's complete significant-ownership history.

Latest filings
TypeFiled
42024-04-23
SC 13D/A2024-04-23
42024-04-22
32024-04-18
SC 13D2024-04-18
32024-04-01
42024-04-01
42024-04-01
42024-04-01
SC 13D2024-04-01

View Baker Brothers Advisors's complete filings history.

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Export Baker Brothers Advisors's holdings