Orbimed Advisors - Q3 2017 holdings

$10.5 Billion is the total value of Orbimed Advisors's 143 reported holdings in Q3 2017. The portfolio turnover from Q2 2017 to Q3 2017 was 21.0% .

 Value Shares↓ Weighting
ALXN SellALEXION PHARMACEUTICALS INC$511,425,000
+8.6%
3,645,486
-5.8%
4.89%
-1.0%
BIIB  BIOGEN INC$510,386,000
+15.4%
1,630,0000.0%4.88%
+5.2%
CELG SellCELGENE CORP$488,785,000
+9.9%
3,351,977
-2.2%
4.67%
+0.2%
BSX SellBOSTON SCIENTIFIC CORP$390,790,000
-2.1%
13,397,000
-7.0%
3.74%
-10.7%
MRK  MERCK & CO INC$351,333,000
-0.1%
5,487,0000.0%3.36%
-8.9%
VRTX BuyVERTEX PHARMACEUTICALS INC$315,377,000
+20.8%
2,074,302
+2.4%
3.01%
+10.1%
PBYI  PUMA BIOTECHNOLOGY INC$290,482,000
+37.0%
2,425,7350.0%2.78%
+24.9%
LLY  LILLY ELI & CO$263,036,000
+3.9%
3,075,0000.0%2.51%
-5.2%
REGN BuyREGENERON PHARMACEUTICALS$256,097,000
+11.7%
572,770
+22.7%
2.45%
+1.8%
CI BuyCIGNA CORPORATION$236,685,000
+15.7%
1,266,100
+3.6%
2.26%
+5.5%
A SellAGILENT TECHNOLOGIES INC$233,617,000
+3.3%
3,638,900
-4.6%
2.23%
-5.8%
AMGN SellAMGEN INC$233,640,000
+4.1%
1,253,100
-3.8%
2.23%
-5.1%
WMGI  WRIGHT MED GROUP N V$231,439,000
-5.9%
8,946,2340.0%2.21%
-14.2%
AET BuyAETNA INC NEW$222,057,000
+64.7%
1,396,500
+57.3%
2.12%
+50.2%
CLVS BuyCLOVIS ONCOLOGY INC$196,826,000
-0.1%
2,388,670
+13.5%
1.88%
-8.9%
ANTM BuyANTHEM INC$176,136,000
+1.7%
927,618
+0.8%
1.68%
-7.3%
CMTA NewCLEMENTIA PHARMACEUTICALS IN$176,082,00010,425,225
+100.0%
1.68%
ABBV SellABBVIE INC$174,610,000
+9.6%
1,965,000
-10.6%
1.67%
-0.1%
ARRY  ARRAY BIOPHARMA INC$174,450,000
+47.0%
14,182,9000.0%1.67%
+34.0%
INCY SellINCYTE CORP$172,308,000
-17.7%
1,476,000
-11.3%
1.65%
-25.0%
LOXO  LOXO ONCOLOGY INC$159,183,000
+14.9%
1,728,0000.0%1.52%
+4.8%
GILD SellGILEAD SCIENCES INC$156,207,000
+6.4%
1,928,000
-7.0%
1.49%
-2.9%
EW SellEDWARDS LIFESCIENCES CORP$152,017,000
-30.1%
1,390,700
-24.4%
1.45%
-36.3%
JNJ  JOHNSON & JOHNSON$146,183,000
-1.7%
1,124,4000.0%1.40%
-10.4%
IMMU BuyIMMUNOMEDICS INC$139,755,000
+221.1%
9,996,816
+102.8%
1.34%
+193.0%
BGNE BuyBEIGENE LTDsponsored adr$135,925,000
+134.6%
1,313,788
+2.0%
1.30%
+114.0%
ALNY BuyALNYLAM PHARMACEUTICALS INC$127,453,000
+150.0%
1,084,800
+69.7%
1.22%
+128.1%
ASND  ASCENDIS PHARMA A Ssponsored adr$122,065,000
+30.6%
3,367,3150.0%1.17%
+19.1%
BOLD SellAUDENTES THERAPEUTICS INC$115,671,000
+25.9%
4,129,638
-14.0%
1.10%
+14.7%
MYL BuyMYLAN N V$112,967,000
-2.3%
3,601,100
+20.9%
1.08%
-10.9%
JAZZ BuyJAZZ PHARMACEUTICALS PLC$109,571,000
+29.1%
749,200
+37.2%
1.05%
+17.6%
SEM BuySELECT MED HLDGS CORP$107,107,000
+89.2%
5,578,500
+51.3%
1.02%
+72.7%
TMO  THERMO FISHER SCIENTIFIC INC$101,071,000
+8.4%
534,2000.0%0.97%
-1.1%
JUNO BuyJUNO THERAPEUTICS INC$91,587,000
+234.8%
2,041,608
+123.1%
0.88%
+204.9%
IRWD  IRONWOOD PHARMACEUTICALS INC$90,823,000
-16.5%
5,759,2000.0%0.87%
-23.9%
PFE  PFIZER INC$87,779,000
+6.3%
2,458,8000.0%0.84%
-3.1%
CRVS  CORVUS PHARMACEUTICALS INC$85,747,000
+31.7%
5,379,3490.0%0.82%
+20.1%
ILMN  ILLUMINA INC$79,381,000
+14.8%
398,5000.0%0.76%
+4.7%
AGN  ALLERGAN PLC$76,567,000
-15.7%
373,5900.0%0.73%
-23.1%
MGLN SellMAGELLAN HEALTH INC$76,168,000
-14.0%
882,600
-27.4%
0.73%
-21.6%
UNH SellUNITEDHEALTH GROUP INC$74,423,000
-6.4%
380,000
-11.3%
0.71%
-14.6%
GBT BuyGLOBAL BLOOD THERAPEUTICS IN$74,322,000
+25.1%
2,393,635
+10.2%
0.71%
+14.0%
UHS NewUNIVERSAL HLTH SVCS INCcl b$74,219,000669,000
+100.0%
0.71%
AERI SellAERIE PHARMACEUTICALS INC$69,896,000
-27.4%
1,438,182
-21.5%
0.67%
-33.8%
BMRN SellBIOMARIN PHARMACEUTICAL INC$69,235,000
-22.4%
743,900
-24.3%
0.66%
-29.2%
MDT  MEDTRONIC PLC$68,360,000
-12.4%
879,0000.0%0.65%
-20.2%
BLUE BuyBLUEBIRD BIO INC$66,195,000
+57.6%
481,946
+20.5%
0.63%
+43.9%
NTLA  INTELLIA THERAPEUTICS INC$66,155,000
+55.3%
2,662,1800.0%0.63%
+41.7%
AGNPRA  ALLERGAN PLCpfd conv ser a$65,076,000
-14.9%
88,2000.0%0.62%
-22.4%
SHPG SellSHIRE PLCsponsored adr$61,242,000
-32.5%
399,908
-27.1%
0.58%
-38.5%
SYK BuySTRYKER CORP$59,790,000
+36.2%
421,000
+33.1%
0.57%
+24.1%
ISRG BuyINTUITIVE SURGICAL INC$58,988,000
+30.8%
56,400
+17.0%
0.56%
+19.2%
ACHN SellACHILLION PHARMACEUTICALS IN$58,652,000
-2.5%
13,062,900
-0.3%
0.56%
-11.1%
INSM SellINSMED INC$58,519,000
-22.4%
1,875,016
-57.3%
0.56%
-29.2%
GWPH  GW PHARMACEUTICALS PLCads$56,943,000
+1.2%
561,0710.0%0.54%
-7.8%
BMY  BRISTOL MYERS SQUIBB CO$55,753,000
+14.4%
874,7000.0%0.53%
+4.3%
IART BuyINTEGRA LIFESCIENCES HLDGS C$55,069,000
+136.6%
1,090,910
+155.5%
0.53%
+115.6%
MNKKQ  MALLINCKRODT PUB LTD CO$55,035,000
-16.6%
1,472,7000.0%0.53%
-24.0%
INSYQ  INSYS THERAPEUTICS INC NEW$54,802,000
-29.8%
6,171,4400.0%0.52%
-35.9%
VRAY  VIEWRAY INC$54,481,000
-11.0%
9,458,5670.0%0.52%
-18.7%
KALA NewKALA PHARMACEUTICALS INC$54,251,0002,375,279
+100.0%
0.52%
GLPG BuyGALAPAGOS NVspon adr$53,296,000
+145.7%
523,790
+84.8%
0.51%
+124.2%
IOVA BuyIOVANCE BIOTHERAPEUTICS INC$49,799,000
+97.6%
6,425,626
+89.9%
0.48%
+80.3%
NVRO BuyNEVRO CORP$44,977,000
+33.9%
494,900
+9.7%
0.43%
+22.2%
EHTH  EHEALTH INC$43,831,000
+27.1%
1,834,7000.0%0.42%
+15.7%
RDUS BuyRADIUS HEALTH INC$43,284,000
+35.9%
1,122,800
+59.5%
0.41%
+24.0%
PIRS  PIERIS PHARMACEUTICALS INC$41,815,000
+13.8%
7,259,6200.0%0.40%
+3.9%
IMGN BuyIMMUNOGEN INC$41,697,000
+48.9%
5,450,581
+38.4%
0.40%
+35.8%
SGYPQ SellSYNERGY PHARMACEUTICALS DEL$39,502,000
-58.0%
13,621,443
-35.6%
0.38%
-61.7%
MNTA  MOMENTA PHARMACEUTICALS INC$39,018,000
+9.5%
2,109,0680.0%0.37%
-0.3%
ONCE NewSPARK THERAPEUTICS INC$38,340,000430,016
+100.0%
0.37%
DERM  DERMIRA INC$38,310,000
-7.3%
1,418,8730.0%0.37%
-15.5%
ALPN NewALPINE IMMUNE SCIENCES INC$38,263,0003,298,516
+100.0%
0.37%
SELB  SELECTA BIOSCIENCES INC$33,631,000
-8.1%
1,842,7970.0%0.32%
-16.4%
DMTX  DIMENSION THERAPEUTICS INC$32,386,000
+313.8%
5,397,6980.0%0.31%
+278.0%
 NABRIVA THERAPEUTICS PLC$32,102,000
-21.8%
3,919,6000.0%0.31%
-28.8%
GKOS SellGLAUKOS CORP$27,605,000
-61.8%
836,500
-52.0%
0.26%
-65.1%
ASMB SellASSEMBLY BIOSCIENCES INC$26,121,000
+42.4%
748,026
-15.8%
0.25%
+30.2%
SYBX NewSYNLOGIC INC$25,005,0001,314,996
+100.0%
0.24%
INCY NewINCYTE CORPput$23,348,000200,000
+100.0%
0.22%
ICPT SellINTERCEPT PHARMACEUTICALS IN$22,425,000
-78.4%
386,380
-54.9%
0.21%
-80.3%
DBVT  DBV TECHNOLOGIES S Asponsored adr$21,767,000
+18.8%
512,9000.0%0.21%
+8.3%
OBSV  OBSEVA SA$21,209,000
-4.8%
2,605,5310.0%0.20%
-13.2%
NTRA BuyNATERA INC$20,317,000
+46.6%
1,576,190
+23.5%
0.19%
+33.8%
EVHC SellENVISION HEALTHCARE CORP$19,809,000
-45.3%
440,700
-23.8%
0.19%
-50.3%
SVA  SINOVAC BIOTECH LTD$18,806,000
+4.4%
2,667,5000.0%0.18%
-4.8%
ZLAB NewZAI LAB LTDadr$17,770,000658,160
+100.0%
0.17%
NBIX  NEUROCRINE BIOSCIENCES INC$17,455,000
+33.2%
284,8410.0%0.17%
+21.9%
VNDA  VANDA PHARMACEUTICALS INC$17,325,000
+9.8%
967,8590.0%0.17%
+0.6%
XNCR  XENCOR INC$17,127,000
+8.6%
747,2440.0%0.16%
-0.6%
CTIC  CTI BIOPHARMA CORP$15,950,000
-3.6%
5,000,0000.0%0.15%
-12.1%
NVO NewNOVO-NORDISK A Sadr$15,890,000330,000
+100.0%
0.15%
ADAP  ADAPTIMMUNE THERAPEUTICS PLCsponds adr$15,681,000
+82.4%
1,914,6600.0%0.15%
+66.7%
SHPG NewSHIRE PLCput$15,314,000100,000
+100.0%
0.15%
HCA SellHCA HEALTHCARE INC$14,915,000
-71.4%
187,400
-68.6%
0.14%
-73.8%
CHRS  COHERUS BIOSCIENCES INC$14,414,000
-7.0%
1,079,7000.0%0.14%
-14.8%
STDY  STEADYMED LTD$14,225,000
-46.8%
4,246,1960.0%0.14%
-51.4%
NVTA BuyINVITAE CORP$14,226,000
+225.8%
1,518,197
+232.5%
0.14%
+195.7%
WMGIZ BuyWRIGHT MED GROUP N Vright 03/01/2019$13,505,000
+6.6%
8,713,088
+0.4%
0.13%
-3.0%
NVUS  NOVUS THERAPEUTICS INC$13,218,000
-10.9%
2,537,1100.0%0.13%
-19.2%
NUVA BuyNUVASIVE INC$12,240,000
+142.6%
220,700
+236.4%
0.12%
+120.8%
 AEGERION PHARMACEUTICALS INCnote 2.000% 8/1$12,151,000
-1.0%
15,000,0000.0%0.12%
-10.1%
ARGX  ARGENX SEsponsored adr$11,305,000
+6.6%
500,0000.0%0.11%
-2.7%
AUPH  AURINIA PHARMACEUTICALS INC$11,270,000
+2.3%
1,797,4000.0%0.11%
-6.1%
PRQR SellPROQR THRAPEUTICS N V$11,132,000
-7.1%
2,295,346
-0.4%
0.11%
-15.9%
HRTX  HERON THERAPEUTICS INC$10,498,000
+16.6%
650,0000.0%0.10%
+6.4%
VRNA  VERONA PHARMA PLCsponsored ads$10,233,000
+31.7%
666,6660.0%0.10%
+21.0%
BMY NewBRISTOL MYERS SQUIBB COcall$9,561,000150,000
+100.0%
0.09%
FLDM  FLUIDIGM CORP DEL$8,800,000
+24.8%
1,746,1000.0%0.08%
+13.5%
NLNK SellNEWLINK GENETICS CORP$8,462,000
-37.6%
831,274
-55.0%
0.08%
-43.0%
DCPH NewDECIPHERA PHARMACEUTICALS IN$7,487,000394,270
+100.0%
0.07%
 FLUIDIGM CORP DELnote 2.750% 2/0$7,390,000
+17.3%
10,000,0000.0%0.07%
+7.6%
ALKS  ALKERMES PLC$7,372,000
-12.3%
145,0000.0%0.07%
-20.5%
AGLE  AEGLEA BIOTHERAPEUTICS INC$7,244,000
+28.0%
1,469,5240.0%0.07%
+16.9%
TEVA SellTEVA PHARMACEUTICAL INDS LTDsponsored adr$7,137,000
-59.2%
405,500
-23.0%
0.07%
-62.8%
SRPT NewSAREPTA THERAPEUTICS INCcall$6,804,000150,000
+100.0%
0.06%
CRSP  CRISPR THERAPEUTICS AGnamen akt$6,651,000
+11.5%
372,1910.0%0.06%
+1.6%
RDHL  REDHILL BIOPHARMA LTDsponsored ads$6,107,000
+25.4%
564,9000.0%0.06%
+13.7%
HALO  HALOZYME THERAPEUTICS INC$6,080,000
+35.5%
350,0000.0%0.06%
+23.4%
SRRA  SIERRA ONCOLOGY INC$5,741,000
+32.5%
3,703,7040.0%0.06%
+22.2%
ZBH  ZIMMER BIOMET HLDGS INC$5,737,000
-8.8%
49,0000.0%0.06%
-16.7%
 INOTEK PHARMACEUTICALS CORPnote 5.750% 8/0$5,547,000
+30.2%
7,000,0000.0%0.05%
+17.8%
SNDX  SYNDAX PHARMACEUTICALS INC$5,113,000
-16.2%
437,0000.0%0.05%
-23.4%
GLYC  GLYCOMIMETICS INC$4,723,000
+25.4%
337,5880.0%0.04%
+15.4%
MCRB NewSERES THERAPEUTICS INC$3,520,000219,458
+100.0%
0.03%
MRNS  MARINUS PHARMACEUTICALS INC$3,332,000
+328.3%
567,6000.0%0.03%
+300.0%
INFI SellINFINITY PHARMACEUTICALS INC$2,936,000
-42.5%
2,207,245
-32.1%
0.03%
-47.2%
VRX  VALEANT PHARMACEUTICALS INTL$2,793,000
-17.2%
194,9000.0%0.03%
-22.9%
OTIC SellOTONOMY INC$2,093,000
-92.9%
644,074
-58.7%
0.02%
-93.5%
 OREXIGEN THERAPEUTICS INCnote 2.750%12/0$2,042,000
-16.4%
5,210,0000.0%0.02%
-23.1%
XENE  XENON PHARMACEUTICALS INC$1,873,000
-6.4%
634,8120.0%0.02%
-14.3%
BLRX  BIOLINERX LTDsponsored adr$1,163,000
+32.5%
1,038,6000.0%0.01%
+22.2%
MCRB NewSERES THERAPEUTICS INCcall$1,203,00075,000
+100.0%
0.01%
NVLNF  NOVELION THERAPEUTICS INC$703,000
-23.8%
100,0000.0%0.01%
-30.0%
AFMD SellAFFIMED N V$735,000
-80.1%
326,650
-81.8%
0.01%
-82.1%
 BIOMARIN PHARMACEUTICAL INCnote 1.500%10/1$602,000
+0.7%
500,0000.0%0.01%0.0%
 BIOMARIN PHARMACEUTICAL INCnote 0.750%10/1$558,000
+0.4%
500,0000.0%0.01%
-16.7%
NLNK NewNEWLINK GENETICS CORPcall$509,00050,000
+100.0%
0.01%
ALIM  ALIMERA SCIENCES INC$338,000
-2.9%
250,0000.0%0.00%
-25.0%
XTNT  XTANT MED HLDGS INC$343,000
+9.2%
475,4390.0%0.00%0.0%
VSAR NewVERSARTIS INCcall$123,00050,000
+100.0%
0.00%
ROKA SellROKA BIOSCIENCE INC$147,000
-93.6%
201,617
-77.4%
0.00%
-95.8%
MDGS  MEDIGUS LTDsponsord adr new$134,000
+2.3%
60,0000.0%0.00%0.0%
AMRN ExitAMARIN CORP PLCspons adr new$0-204,857
-100.0%
-0.01%
CLLS ExitCELLECTIS S Asponsored ads$0-66,799
-100.0%
-0.02%
NERV ExitMINERVA NEUROSCIENCES INC$0-344,173
-100.0%
-0.03%
TSRO ExitTESARO INC$0-30,301
-100.0%
-0.04%
SIEN ExitSIENTRA INC$0-483,347
-100.0%
-0.05%
NVRO ExitNEVRO CORPcall$0-75,000
-100.0%
-0.06%
AZN ExitASTRAZENECA PLCput$0-250,000
-100.0%
-0.09%
MNKKQ ExitMALLINCKRODT PUB LTD COput$0-200,000
-100.0%
-0.09%
JAZZ ExitJAZZ PHARMACEUTICALS PLCcall$0-100,000
-100.0%
-0.16%
ExitIMMUNOGEN INCnote 4.500% 7/0$0-10,000,000
-100.0%
-0.19%
ExitIMMUNOMEDICS INCnote 4.750% 2/1$0-30,000,000
-100.0%
-0.57%
HUM ExitHUMANA INC$0-770,900
-100.0%
-1.94%
Other managers

Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):

Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR filed 2017-11-14
Signatures

The EDGAR filing(s) were signed by:

About Orbimed Advisors

Orbimed Advisors is a leading healthcare-focused investment firm that manages over $16 billion in assets. The firm was founded in 1998 by Samuel Isaly, who has over 50 years of experience in the healthcare industry. Isaly is widely regarded as a pioneer in the field of healthcare investing and has been recognized for his contributions to the industry by numerous organizations.

Orbimed Advisors has a team of over 100 professionals, including investment professionals, research analysts, and operational experts. The firm has offices in New York, San Francisco, Shanghai, and Mumbai, and invests in companies across the healthcare spectrum, including biotechnology, pharmaceuticals, medical devices, and healthcare services.

The firm's investment philosophy is based on a deep understanding of the healthcare industry and a rigorous approach to due diligence. Orbimed Advisors seeks to identify companies with innovative technologies and strong management teams that have the potential to transform the healthcare landscape.

Orbimed Advisors has a strong track record of success, with numerous successful investments in companies such as Juno Therapeutics, Spark Therapeutics, and Kite Pharma. The firm's leadership team, which includes CEO Sven Borho, COO Jonathan Silverstein, and Chief Investment Officer Carl Gordon, has decades of experience in the healthcare industry and is widely respected for their expertise and insights.

Overall, Orbimed Advisors is a leading healthcare investment firm that has a proven track record of success and a deep understanding of the healthcare industry. Investors looking to gain exposure to the healthcare sector may want to consider Orbimed Advisors as a potential investment opportunity.

It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
BIOGEN INC42Q3 20235.0%
VERTEX PHARMACEUTICALS INC42Q3 20233.7%
THERMO FISHER SCIENTIFIC INC42Q3 20233.2%
SINOVAC BIOTECH LTD41Q3 20237.2%
NEUROCRINE BIOSCIENCES INC41Q3 20232.7%
BOSTON SCIENTIFIC CORP40Q3 20235.6%
BRISTOL-MYERS SQUIBB CO40Q2 20235.2%
AMGEN INC40Q3 20235.5%
INTUITIVE SURGICAL INC40Q3 20233.8%
GILEAD SCIENCES INC39Q3 20235.5%

View Orbimed Advisors's complete holdings history.

Latest significant ownerships (13-D/G)
Orbimed Advisors Q3 2017 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
Ikena Oncology, Inc.September 21, 20232,189,1115.2%
Galecto, Inc.September 18, 2023749,5572.8%
PMV Pharmaceuticals, Inc.August 23, 20236,563,07713.5%
Gracell Biotechnologies Inc.August 11, 20237,641,5318.0%
Xtant Medical Holdings, Inc.August 03, 202373,114,59256.7%
Turnstone Biologics Corp.July 24, 20233,099,26513.4%
Prelude Therapeutics IncMay 24, 202315,716,64228.6%
VectivBio Holding AGMay 24, 20235,156,5617.7%
Fusion Pharmaceuticals Inc.May 16, 20232,930,6704.6%
Verona Pharma plcMay 16, 20233,777,7784.8%

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Latest filings
TypeFiled
42024-04-26
42024-04-23
42024-04-18
42024-04-15
3/A2024-04-12
SC 13D/A2024-04-12
42024-04-05
SC 13D/A2024-04-04
32024-04-03
SC 13D2024-03-28

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