| Type | Filed | Filer | Subject | Shares Owned | Percent Owned | |
|---|---|---|---|---|---|---|
| SC 13G/A | 2018-02-14 | Flynn James E | Horizon Pharma plc | 6,341,894 | 3.9% | EDGAR |
| SC 13G | 2018-02-13 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | Horizon Pharma plc | 8,791,589 | 5.4% | EDGAR |
| SC 13G/A | 2018-02-08 | VANGUARD GROUP INC | Horizon Pharma plc | 13,475,093 | 8.2% | EDGAR |
| SC 13G/A | 2018-01-30 | BlackRock Inc. | Horizon Pharma plc | 13,445,553 | 8.2% | EDGAR |
| SC 13G | 2017-02-15 | KINGDON CAPITAL MANAGEMENT, L.L.C. | Horizon Pharma plc | 12,748,199 | 7.8% | EDGAR |
| SC 13G/A | 2017-02-14 | FMR LLC | Horizon Pharma plc | 6,526,611 | 4.0% | EDGAR |
| SC 13G/A | 2017-02-14 | LONE PINE CAPITAL LLC | Horizon Pharma plc | 0 | 0.0% | EDGAR |
| SC 13G/A | 2017-02-14 | Flynn James E | Horizon Pharma plc | 8,956,988 | 5.6% | EDGAR |
| SC 13G/A | 2017-02-13 | VANGUARD GROUP INC | Horizon Pharma plc | 12,242,679 | 7.6% | EDGAR |
| SC 13G/A | 2017-02-10 | Broadfin Capital, LLC | Horizon Pharma plc | 6,759,819 | 4.2% | EDGAR |
| SC 13G | 2017-01-30 | BlackRock Inc. | Horizon Pharma plc | 13,067,967 | 8.1% | EDGAR |
| SC 13G/A | 2016-10-11 | FMR LLC | Horizon Pharma plc | 13,604,036 | 8.4% | EDGAR |
| SC 13G/A | 2016-02-16 | LONE PINE CAPITAL LLC | Horizon Pharma plc | 15,600,988 | 9.8% | EDGAR |
| SC 13G/A | 2016-02-16 | KINGDON CAPITAL MANAGEMENT, L.L.C. | Horizon Pharma plc | 4,776,229 | 3.0% | EDGAR |
| SC 13G/A | 2016-02-16 | Flynn James E | Horizon Pharma plc | 11,684,801 | 7.3% | EDGAR |
| SC 13G/A | 2016-02-12 | FMR LLC | Horizon Pharma plc | 23,968,894 | 15.0% | EDGAR |
| SC 13G/A | 2016-02-12 | Broadfin Capital, LLC | Horizon Pharma plc | 8,631,310 | 5.4% | EDGAR |
| SC 13G | 2016-02-11 | VANGUARD GROUP INC | Horizon Pharma plc | 9,567,662 | 6.0% | EDGAR |
| SC 13G | 2015-07-27 | LONE PINE CAPITAL LLC | Horizon Pharma plc | 8,353,668 | 5.4% | EDGAR |
| SC 13G | 2015-05-11 | FMR LLC | Horizon Pharma plc | 17,590,380 | 11.4% | EDGAR |