| SC 13G/A | 2018-02-13 | FMR LLC | Spark Therapeutics, Inc. | 5,550,816 | 15.0% | EDGAR |
| SC 13G/A | 2018-02-12 | VANGUARD GROUP INC | Spark Therapeutics, Inc. | 2,577,279 | 7.0% | EDGAR |
| SC 13G/A | 2018-02-12 | VANGUARD GROUP INC | Spark Therapeutics, Inc. | 2,577,279 | 7.0% | EDGAR |
| SC 13G/A | 2018-01-23 | BlackRock Inc. | Spark Therapeutics, Inc. | 2,650,258 | 7.2% | EDGAR |
| SC 13G | 2018-01-11 | JPMORGAN CHASE & CO | Spark Therapeutics, Inc. | 2,239,459 | 6.0% | EDGAR |
| SC 13D/A | 2017-06-01 | Children's Hospital of Philadelphia Foundation | Spark Therapeutics, Inc. | 4,998,910 | 16.0% | EDGAR |
| SC 13G/A | 2017-02-14 | FMR LLC | Spark Therapeutics, Inc. | 4,615,957 | 15.0% | EDGAR |
| SC 13G | 2017-02-13 | VANGUARD GROUP INC | Spark Therapeutics, Inc. | 1,736,974 | 5.6% | EDGAR |
| SC 13G/A | 2017-02-10 | PRICE T ROWE ASSOCIATES INC /MD/ | Spark Therapeutics, Inc. | 3,210,596 | 10.4% | EDGAR |
| SC 13G/A | 2017-02-07 | PRICE T ROWE ASSOCIATES INC /MD/ | Spark Therapeutics, Inc. | 3,041,716 | 9.8% | EDGAR |
| SC 13G | 2017-01-30 | BlackRock Inc. | Spark Therapeutics, Inc. | 1,841,654 | 6.0% | EDGAR |
| SC 13D/A | 2016-12-22 | Sofinnova Venture Partners VIII, L.P. | Spark Therapeutics, Inc. | 904,986 | 2.9% | EDGAR |
| SC 13G/A | 2016-12-12 | PRICE T ROWE ASSOCIATES INC /MD/ | Spark Therapeutics, Inc. | 3,256,841 | 10.5% | EDGAR |
| SC 13D/A | 2016-08-31 | Children's Hospital of Philadelphia Foundation | Spark Therapeutics, Inc. | 5,838,910 | 19.0% | EDGAR |
| SC 13D/A | 2016-07-05 | Children's Hospital of Philadelphia Foundation | Spark Therapeutics, Inc. | 6,838,910 | 22.7% | EDGAR |
| SC 13G/A | 2016-02-12 | FMR LLC | Spark Therapeutics, Inc. | 4,019,544 | 15.0% | EDGAR |
| SC 13G | 2016-02-12 | PRICE T ROWE ASSOCIATES INC /MD/ | Spark Therapeutics, Inc. | 2,052,928 | 7.6% | EDGAR |
| SC 13D/A | 2016-01-07 | Children's Hospital of Philadelphia Foundation | Spark Therapeutics, Inc. | 7,832,910 | 28.9% | EDGAR |
| SC 13D/A | 2015-12-22 | Children's Hospital of Philadelphia Foundation | Spark Therapeutics, Inc. | 7,964,415 | 29.7% | EDGAR |
| SC 13D/A | 2015-10-21 | Sofinnova Venture Partners VIII, L.P. | Spark Therapeutics, Inc. | 1,589,032 | 6.5% | EDGAR |