| Tri Locum Partners LP | 198,532 | $6,450,305 | 2.40% |
|---|
| NEXT CENTURY GROWTH INVESTORS LLC | 739,915 | $24,039,838 | 2.32% |
|---|
| Parkman Healthcare Partners LLC | 307,525 | $9,991,487 | 1.73% |
|---|
| Bullseye Asset Management LLC | 79,902 | $2,596 | 1.30% |
|---|
| Millrace Asset Group, Inc. | 33,697 | $1,095 | 1.15% |
|---|
| Pier Capital, LLC | 227,659 | $7,396,641 | 1.06% |
|---|
| WASATCH ADVISORS LP | 5,246,961 | $170,473,763 | 1.03% |
|---|
| Novo Holdings A/S | 333,884 | $10,847,891 | 0.84% |
|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 1,132,229 | $36,786,120 | 0.78% |
|---|
| Bellevue Group AG | 1,356,763 | $44,081,230 | 0.63% |
|---|
| Birchview Capital, LP | 20,000 | $649,800 | 0.49% |
|---|
| SECTORAL ASSET MANAGEMENT INC | 80,500 | $2,615,445 | 0.44% |
|---|
| PEREGRINE CAPITAL MANAGEMENT LLC | 363,074 | $11,796,274 | 0.32% |
|---|
| Point72 Europe (London) LLP | 57,480 | $1,867,525 | 0.24% |
|---|
| KLR INVESTMENT ADVISORS, LLC | 8,800 | $285,912 | 0.24% |
|---|
| FRED ALGER MANAGEMENT, LLC | 1,241,469 | $40,335,328 | 0.21% |
|---|
| TimesSquare Capital Management, LLC | 377,325 | $12,259 | 0.18% |
|---|
| Asset Management Resources, LLC | 8,028 | $260,830 | 0.16% |
|---|
| Granahan Investment Management | 154,277 | $5,012,460 | 0.15% |
|---|
| Engineers Gate Manager LP | 123,518 | $4,013,100 | 0.15% |
|---|