| Tikvah Management LLC | 571,619 | $12,890,008 | 4.38% |
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| Kent Lake Capital LLC | 400,000 | $9,020,000 | 4.14% |
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| BOONE CAPITAL MANAGEMENT LLC | 501,144 | $11,300,797 | 4.06% |
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| PURA VIDA INVESTMENTS, LLC | 1,102,062 | $24,851,498 | 3.29% |
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| Portolan Capital Management | 1,416,623 | $31,944,849 | 2.83% |
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| ASHFORD CAPITAL MANAGEMENT INC | 890,588 | $20,082,759 | 2.81% |
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| Camber Capital Management LP | 3,425,000 | $77,234 | 2.52% |
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| BRIDGER MANAGEMENT, LLC | 154,900 | $3,492,995 | 1.16% |
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| Granahan Investment Management | 1,178,512 | $26,575,446 | 0.82% |
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| MARATHON CAPITAL MANAGEMENT | 101,920 | $2,298,296 | 0.57% |
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| PLATINUM INVESTMENT MANAGEMENT LTD | 716,001 | $16,145,823 | 0.56% |
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| EAM Investors, LLC | 116,562 | $2,628,473 | 0.49% |
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| GILDER GAGNON HOWE & CO LLC | 1,268,202 | $28,597,960 | 0.39% |
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| Diametric Capital, LP | 37,872 | $854,014 | 0.38% |
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| China Universal Asset Management Co., Ltd. | 51,148 | $1,153 | 0.36% |
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| Olympiad Research LP | 13,667 | $308,191 | 0.30% |
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| Hillsdale Investment Management Inc. | 96,320 | $2,172,016 | 0.20% |
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| Parkman Healthcare Partners LLC | 50,144 | $1,130,747 | 0.20% |
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| FRONTIER CAPITAL MANAGEMENT CO LLC | 811,856 | $18,307,353 | 0.18% |
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| IRONWOOD INVESTMENT MANAGEMENT LLC | 11,301 | $254,838 | 0.15% |
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