| SC 13D/A | 2012-01-13 | DOMAIN PARTERS VII L P | Orexigen Therapeutics, Inc. | 7,580,065 | 14.4% | EDGAR |
| SC 13G | 2011-12-27 | QVT Financial LP | Orexigen Therapeutics, Inc. | 5,293,458 | 9.8% | EDGAR |
| SC 13G/A | 2011-02-18 | Growth Equity Opportunities Fund, LLC | Orexigen Therapeutics, Inc. | - | - | EDGAR |
| SC 13G/A | 2011-02-15 | Arkin Moshe | Orexigen Therapeutics, Inc. | - | 0.0% | EDGAR |
| SC 13G/A | 2011-02-10 | Scale Venture Partners II, LP | Orexigen Therapeutics, Inc. | 3,067,167 | 6.4% | EDGAR |
| SC 13G/A | 2011-02-10 | Arkin Moshe | Orexigen Therapeutics, Inc. | - | 0.0% | EDGAR |
| SC 13G | 2011-01-31 | SAC Capital Advisors LP | Orexigen Therapeutics, Inc. | 2,370,400 | 5.0% | EDGAR |
| SC 13G/A | 2011-01-10 | FMR LLC | Orexigen Therapeutics, Inc. | 824,413 | 1.7% | EDGAR |
| SC 13G | 2010-12-21 | Growth Equity Opportunities Fund, LLC | Orexigen Therapeutics, Inc. | 2,856,700 | 6.0% | EDGAR |
| SC 13G/A | 2010-07-12 | Arkin Moshe | Orexigen Therapeutics, Inc. | 4,869,643 | 10.3% | EDGAR |
| SC 13G/A | 2010-06-17 | Arkin Moshe | Orexigen Therapeutics, Inc. | 4,869,643 | 10.3% | EDGAR |
| SC 13G/A | 2010-05-10 | FMR LLC | Orexigen Therapeutics, Inc. | 5,812,934 | 12.3% | EDGAR |
| SC 13G/A | 2010-04-12 | FMR LLC | Orexigen Therapeutics, Inc. | 3,413,547 | 7.2% | EDGAR |
| SC 13G/A | 2010-02-16 | FMR LLC | Orexigen Therapeutics, Inc. | 6,338,864 | 13.5% | EDGAR |
| SC 13G/A | 2010-02-10 | SOFINNOVA VENTURE PARTNERS VI L P | Orexigen Therapeutics, Inc. | 1,635,055 | 3.5% | EDGAR |
| SC 13G/A | 2010-02-10 | FEDERATED INVESTORS INC /PA/ | Orexigen Therapeutics, Inc. | 443,514 | 0.9% | EDGAR |
| SC 13G | 2010-02-10 | FEDERATED INVESTORS INC /PA/ | Orexigen Therapeutics, Inc. | 2,360,706 | 5.0% | EDGAR |
| SC 13G | 2010-02-09 | Arkin Moshe | Orexigen Therapeutics, Inc. | 2,860,888 | 6.1% | EDGAR |
| SC 13G/A | 2010-01-28 | Scale Venture Partners II, LP | Orexigen Therapeutics, Inc. | 3,042,445 | 6.5% | EDGAR |
| SC 13D/A | 2009-12-03 | DOMAIN PARTERS VII L P | Orexigen Therapeutics, Inc. | 2,370,366 | 5.0% | EDGAR |