| Evolutionary Tree Capital Management, LLC | 12,998 | $4,219,671 | 5.08% |
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| Atika Capital Management LLC | 140,165 | $45,503,165 | 4.56% |
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| Eagle Health Investments LP | 72,843 | $23,647,752 | 4.42% |
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| Integral Health Asset Management, LLC | 103,000 | $33,437,920 | 4.14% |
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| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 282,068 | $91,570,556 | 3.39% |
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| Kopp Family Office, LLC | 18,112 | $5,880 | 3.16% |
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| Iron Triangle Partners LP | 70,000 | $22,724,800 | 3.04% |
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| Nicholas Investment Partners, LP | 115,187 | $37,394,308 | 2.56% |
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| PURA VIDA INVESTMENTS, LLC | 55,171 | $17,910,713 | 2.37% |
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| Eversept Partners, LP | 82,445 | $26,764,945 | 2.24% |
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| GILDER GAGNON HOWE & CO LLC | 496,053 | $161,038,727 | 2.20% |
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| Bullseye Asset Management LLC | 13,187 | $4,281 | 2.15% |
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| AtonRa Partners | 3,553 | $1,153,446 | 1.79% |
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| Bellevue Group AG | 357,020 | $115,902,973 | 1.65% |
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| Leverage Partners Absolute Return Fund SPC | 5,000 | $1,623 | 1.51% |
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| DRIEHAUS CAPITAL MANAGEMENT LLC | 353,449 | $114,743,683 | 1.45% |
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| Park West Asset Management LLC | 50,000 | $16,232,000 | 1.42% |
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| Lisanti Capital Growth, LLC | 28,968 | $9,404,172 | 1.30% |
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| SECTORAL ASSET MANAGEMENT INC | 24,000 | $7,791,360 | 1.30% |
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| EAM Global Investors LLC | 13,482 | $4,376,797 | 1.29% |
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