| VR Adviser, LLC | 2,105,386 | $21,580,207 | 4.21% |
|---|
| COMMODORE CAPITAL LP | 1,390,772 | $14,255,413 | 2.17% |
|---|
| Soleus Capital Management, L.P. | 1,687,933 | $17,301,313 | 1.79% |
|---|
| NEA Management Company, LLC | 1,250,001 | $12,812,510 | 0.89% |
|---|
| JACOB ASSET MANAGEMENT OF NEW YORK LLC | 68,209 | $699,142 | 0.82% |
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| RA Capital Management | 1,400,001 | $14,350,010 | 0.32% |
|---|
| PFM Health Sciences, LP | 310,965 | $3,187,391 | 0.14% |
|---|
| GAGNON SECURITIES LLC | 54,022 | $553,725 | 0.12% |
|---|
| JNBA Financial Advisors | 38,091 | $390,433 | 0.05% |
|---|
| Murphy Pohlad Asset Management LLC | 11,200 | $114,800 | 0.05% |
|---|
| PUNCH & ASSOCIATES INVESTMENT MANAGEMENT, INC. | 60,000 | $615,000 | 0.04% |
|---|
| Pointe Capital Management LLC | 4,000 | $41,000 | 0.03% |
|---|
| CAPTRUST FINANCIAL ADVISORS | 570,145 | $5,843,986 | 0.03% |
|---|
| Accredited Investors Inc. | 29,115 | $298,429 | 0.02% |
|---|
| 683 Capital Management, LLC | 13,800 | $141,450 | 0.01% |
|---|
| Tradition Wealth Management, LLC | 3,850 | $39 | 0.01% |
|---|
| Cresset Asset Management, LLC | 13,223 | $135,536 | 0.00% |
|---|
| MILLENNIUM MANAGEMENT LLC | 392,167 | $4,020 | 0.00% |
|---|
| MORGAN STANLEY | 1,324,513 | $13,576,259 | 0.00% |
|---|
| Qube Research & Technologies Ltd | 20,874 | $213,959 | 0.00% |
|---|