| Type | Filed | Filer | Subject | Shares Owned | Percent Owned | |
|---|---|---|---|---|---|---|
| SC 13G | 2011-02-08 | BlackRock Inc. | TARGACEPT INC | 1,879,860 | 6.6% | EDGAR |
| SC 13G/A | 2010-02-16 | FMR LLC | TARGACEPT INC | 4,099,654 | 14.8% | EDGAR |
| SC 13G/A | 2010-02-16 | BIOTECHNOLOGY VALUE FUND L P | TARGACEPT INC | 418,368 | 1.5% | EDGAR |
| SC 13G/A | 2010-02-12 | WELLINGTON MANAGEMENT CO LLP | TARGACEPT INC | 3,408,215 | 12.3% | EDGAR |
| SC 13G/A | 2010-02-12 | NOMURA INTERNATIONAL PLC | TARGACEPT INC | 519,716 | 1.9% | EDGAR |
| SC 13G/A | 2010-02-12 | GLAXOSMITHKLINE PLC | TARGACEPT INC | 1,013,553 | 4.0% | EDGAR |
| SC 13G/A | 2010-02-12 | Visium Asset Management, LP | TARGACEPT INC | 1,352,059 | 4.9% | EDGAR |
| SC 13G | 2010-02-12 | SECTORAL ASSET MANAGEMENT INC | TARGACEPT INC | 1,464,412 | 5.3% | EDGAR |
| SC 13G/A | 2010-02-03 | EuclidSR Partners, L.P. | TARGACEPT INC | 556,631 | 2.0% | EDGAR |
| SC 13G/A | 2009-10-20 | BIOTECHNOLOGY VALUE FUND L P | TARGACEPT INC | 465,425 | 1.8% | EDGAR |
| SC 13G | 2009-09-10 | FMR LLC | TARGACEPT INC | 2,802,911 | 11.2% | EDGAR |
| SC 13G | 2009-08-03 | Visium Asset Management, LP | TARGACEPT INC | 1,420,323 | 5.7% | EDGAR |
| SC 13G/A | 2009-07-14 | BIOTECHNOLOGY VALUE FUND L P | TARGACEPT INC | 653,509 | 2.6% | EDGAR |
| SC 13G/A | 2009-02-17 | GLAXOSMITHKLINE PLC | TARGACEPT INC | 1,424,176 | 5.7% | EDGAR |
| SC 13G/A | 2009-02-17 | WELLINGTON MANAGEMENT CO LLP | TARGACEPT INC | 3,304,882 | 13.2% | EDGAR |
| SC 13G/A | 2009-02-12 | EuclidSR Partners, L.P. | TARGACEPT INC | 1,152,631 | 4.6% | EDGAR |
| SC 13G/A | 2009-01-27 | BIOTECHNOLOGY VALUE FUND L P | TARGACEPT INC | 472,301 | 1.9% | EDGAR |
| SC 13G/A | 2008-02-14 | BIOTECHNOLOGY VALUE FUND L P | TARGACEPT INC | 230,530 | 1.1% | EDGAR |
| SC 13G/A | 2008-02-14 | WELLINGTON MANAGEMENT CO LLP | TARGACEPT INC | 1,632,159 | 8.0% | EDGAR |
| SC 13G/A | 2008-02-12 | OXFORD BIOSCIENCE PARTNERS IV LP | TARGACEPT INC | - | - | EDGAR |