$10.5 Billion is the total value of Orbimed Advisors's 131 reported holdings in Q4 2014. The portfolio turnover from Q3 2014 to Q4 2014 was 34.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BIIB | Buy | BIOGEN IDEC INC | $507,376,000 | +28.9% | 1,494,700 | +25.6% | 4.85% | +17.9% |
| BMY | Buy | BRISTOL MYERS SQUIBB CO | $453,864,000 | +21.6% | 7,688,700 | +5.4% | 4.34% | +11.3% |
| AMGN | Buy | AMGEN INC | $431,357,000 | +18.0% | 2,708,000 | +4.0% | 4.12% | +7.9% |
| CELG | Buy | CELGENE CORP | $409,139,000 | +29.7% | 3,657,600 | +9.9% | 3.91% | +18.7% |
| GILD | Buy | GILEAD SCIENCES INC | $400,558,000 | +0.0% | 4,249,500 | +13.0% | 3.83% | -8.5% |
| B108PS | Buy | ACTAVIS PLC | $383,078,000 | +10.5% | 1,488,200 | +3.6% | 3.66% | +1.2% |
| HCA | Buy | HCA HOLDINGS INC | $316,164,000 | +6.4% | 4,308,000 | +2.3% | 3.02% | -2.6% |
| ILMN | Buy | ILLUMINA INC | $272,551,000 | +23.8% | 1,476,600 | +9.9% | 2.60% | +13.3% |
| ISRG | Buy | INTUITIVE SURGICAL INC | $232,734,000 | +30.4% | 440,000 | +13.9% | 2.22% | +19.3% |
| IPXL | Buy | IMPAX LABORATORIES INC | $211,559,000 | +39.3% | 6,678,000 | +4.3% | 2.02% | +27.5% |
| PRGO | Buy | PERRIGO CO PLC | $208,582,000 | +21.3% | 1,247,800 | +9.0% | 1.99% | +11.0% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $205,667,000 | +35.6% | 1,731,200 | +28.2% | 1.96% | +24.1% |
| HNT | Buy | HEALTH NET INC | $198,671,000 | +40.3% | 3,711,400 | +20.9% | 1.90% | +28.3% |
| COO | Buy | COOPER COS INC | $197,847,000 | +11.2% | 1,220,600 | +6.8% | 1.89% | +1.7% |
| ESRX | Buy | EXPRESS SCRIPTS HLDG CO | $195,334,000 | +31.8% | 2,307,000 | +10.0% | 1.87% | +20.6% |
| MOH | Buy | MOLINA HEALTHCARE INC | $191,739,000 | +65.6% | 3,581,900 | +30.8% | 1.83% | +51.4% |
| MRK | Buy | MERCK & CO INC NEW | $165,560,000 | +4.9% | 2,915,300 | +9.5% | 1.58% | -4.0% |
| REGN | Buy | REGENERON PHARMACEUTICALS | $160,080,000 | +20.1% | 390,200 | +5.6% | 1.53% | +9.9% |
| MCK | Buy | MCKESSON CORP | $154,024,000 | +11.8% | 742,000 | +4.8% | 1.47% | +2.2% |
| ZBH | Buy | ZIMMER HLDGS INC | $145,484,000 | +14.9% | 1,282,700 | +1.8% | 1.39% | +5.1% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $133,339,000 | +46.9% | 5,968,600 | +3.0% | 1.27% | +34.4% |
| P103PS | Buy | NPS PHARMACEUTICALS INC | $105,697,000 | +55.4% | 2,954,900 | +13.0% | 1.01% | +42.3% |
| SYK | Buy | STRYKER CORP | $97,311,000 | +20.2% | 1,031,600 | +2.9% | 0.93% | +9.9% |
| PODD | Buy | INSULET CORP | $91,982,000 | +27.8% | 1,997,000 | +2.3% | 0.88% | +16.9% |
| PFE | Buy | PFIZER INC | $85,943,000 | +8.9% | 2,759,000 | +3.3% | 0.82% | -0.5% |
| MGLN | Buy | MAGELLAN HEALTH INC | $72,516,000 | +229.1% | 1,208,000 | +200.0% | 0.69% | +201.3% |
| FLDM | Buy | FLUIDIGM CORP DEL | $72,054,000 | +40.0% | 2,136,200 | +1.7% | 0.69% | +28.3% |
| T107PS | Buy | WRIGHT MED GROUP INC | $67,900,000 | -8.3% | 2,527,000 | +3.4% | 0.65% | -16.0% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $61,430,000 | +18.7% | 332,000 | +6.4% | 0.59% | +8.7% |
| MNKKQ | Buy | MALLINCKRODT PUB LTD CO | $56,150,000 | +111.9% | 567,001 | +92.9% | 0.54% | +93.9% |
| SIEN | New | SIENTRA INC | $53,481,000 | – | 3,185,308 | +100.0% | 0.51% | – |
| AGN | New | ALLERGAN INCcall | $53,148,000 | – | 250,000 | +100.0% | 0.51% | – |
| INSYQ | Buy | INSYS THERAPEUTICS INC NEW | $52,413,000 | +83.7% | 1,243,200 | +69.0% | 0.50% | +68.1% |
| JNJ | Buy | JOHNSON & JOHNSON | $51,762,000 | +14.8% | 495,000 | +17.0% | 0.50% | +5.1% |
| NUVA | Buy | NUVASIVE INC | $50,556,000 | +119.0% | 1,072,000 | +61.9% | 0.48% | +100.4% |
| TSRO | New | TESARO INC | $49,463,000 | – | 1,330,000 | +100.0% | 0.47% | – |
| EXAS | Buy | EXACT SCIENCES CORP | $48,788,000 | +46.1% | 1,778,000 | +3.2% | 0.47% | +33.5% |
| PBYI | Buy | PUMA BIOTECHNOLOGY INC | $47,488,000 | -6.5% | 250,900 | +17.8% | 0.45% | -14.5% |
| CLVS | New | CLOVIS ONCOLOGY INC | $39,990,000 | – | 714,100 | +100.0% | 0.38% | – |
| PRQR | Buy | PROQR THRAPEUTICS N V | $39,643,000 | +142.7% | 1,829,400 | +92.6% | 0.38% | +121.6% |
| OPHT | Buy | OPHTHOTECH CORP | $38,669,000 | +193.2% | 861,800 | +154.4% | 0.37% | +168.1% |
| MDT | Buy | MEDTRONIC INC | $35,652,000 | +36.0% | 493,800 | +16.7% | 0.34% | +24.5% |
| ARRY | Buy | ARRAY BIOPHARMA INC | $34,282,000 | +50.0% | 7,247,700 | +13.2% | 0.33% | +37.2% |
| CAH | Buy | CARDINAL HEALTH INC | $26,237,000 | +26.4% | 325,000 | +17.3% | 0.25% | +15.7% |
| KYTH | New | KYTHERA BIOPHARMACEUTICALS I | $25,070,000 | – | 722,900 | +100.0% | 0.24% | – |
| UNH | Buy | UNITEDHEALTH GROUP INC | $23,756,000 | +37.7% | 235,000 | +17.5% | 0.23% | +26.1% |
| VRX | Buy | VALEANT PHARMACEUTICALS INTL | $23,184,000 | +28.0% | 162,000 | +17.4% | 0.22% | +17.5% |
| F113PS | Buy | COVIDIEN PLC | $21,602,000 | +38.3% | 211,200 | +16.9% | 0.21% | +26.4% |
| FWP | New | FORWARD PHARMA A/Ssponsored adr | $20,009,000 | – | 960,600 | +100.0% | 0.19% | – |
| AMAG | Buy | AMAG PHARMACEUTICALS INC | $19,989,000 | +296.4% | 469,000 | +196.8% | 0.19% | +260.4% |
| RCPT | New | RECEPTOS INC | $19,124,000 | – | 156,100 | +100.0% | 0.18% | – |
| ANTM | New | ANTHEM INC | $17,443,000 | – | 138,800 | +100.0% | 0.17% | – |
| XNCR | Buy | XENCOR INC | $16,778,000 | +114.9% | 1,046,000 | +24.7% | 0.16% | +95.1% |
| HZNP | Buy | HORIZON PHARMA PLC | $13,857,000 | +25.9% | 1,075,000 | +20.0% | 0.13% | +14.8% |
| MEIP | Buy | MEI PHARMA INC | $10,353,000 | -22.0% | 2,424,500 | +26.0% | 0.10% | -28.8% |
| MDXG | Buy | MIMEDX GROUP INC | $9,648,000 | +70.1% | 836,800 | +5.2% | 0.09% | +55.9% |
| ABT | Buy | ABBOTT LABS | $9,499,000 | +26.9% | 211,000 | +17.2% | 0.09% | +16.7% |
| AEGR | New | AEGERION PHARMACEUTICALS INCcall | $8,376,000 | – | 400,000 | +100.0% | 0.08% | – |
| AET | Buy | AETNA INC NEW | $8,350,000 | +28.9% | 94,000 | +17.5% | 0.08% | +17.6% |
| New | OREXIGEN THERAPEUTICS INCnote 2.750%12/0 | $7,538,000 | – | 7,500,000 | +100.0% | 0.07% | – | |
| New | INCYTE CORPnote 1.250%11/1 | $6,558,000 | – | 4,250,000 | +100.0% | 0.06% | – | |
| RGLS | New | REGULUS THERAPEUTICS INC | $6,416,000 | – | 400,000 | +100.0% | 0.06% | – |
| New | INCYTE CORPnote 0.375%11/1 | $6,425,000 | – | 4,250,000 | +100.0% | 0.06% | – | |
| DVA | Buy | DAVITA HEALTHCARE PARTNERS I | $5,756,000 | +21.1% | 76,000 | +16.9% | 0.06% | +10.0% |
| ASPX | New | AUSPEX PHARMACEUTICALS INC | $4,912,000 | – | 93,600 | +100.0% | 0.05% | – |
| BSX | Buy | BOSTON SCIENTIFIC CORP | $4,240,000 | +32.1% | 320,000 | +17.8% | 0.04% | +20.6% |
| SGEN | New | SEATTLE GENETICS INCput | $3,213,000 | – | 100,000 | +100.0% | 0.03% | – |
| CNXR | New | CONNECTURE INC | $2,724,000 | – | 302,300 | +100.0% | 0.03% | – |
| SGMO | New | SANGAMO BIOSCIENCES INCcall | $1,521,000 | – | 100,000 | +100.0% | 0.02% | – |
| CEMP | New | CEMPRA INC | $1,176,000 | – | 50,000 | +100.0% | 0.01% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2015-02-13
About Orbimed Advisors
Orbimed Advisors is a leading healthcare-focused investment firm that manages over $16 billion in assets. The firm was founded in 1998 by Samuel Isaly, who has over 50 years of experience in the healthcare industry. Isaly is widely regarded as a pioneer in the field of healthcare investing and has been recognized for his contributions to the industry by numerous organizations.
Orbimed Advisors has a team of over 100 professionals, including investment professionals, research analysts, and operational experts. The firm has offices in New York, San Francisco, Shanghai, and Mumbai, and invests in companies across the healthcare spectrum, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
The firm's investment philosophy is based on a deep understanding of the healthcare industry and a rigorous approach to due diligence. Orbimed Advisors seeks to identify companies with innovative technologies and strong management teams that have the potential to transform the healthcare landscape.
Orbimed Advisors has a strong track record of success, with numerous successful investments in companies such as Juno Therapeutics, Spark Therapeutics, and Kite Pharma. The firm's leadership team, which includes CEO Sven Borho, COO Jonathan Silverstein, and Chief Investment Officer Carl Gordon, has decades of experience in the healthcare industry and is widely respected for their expertise and insights.
Overall, Orbimed Advisors is a leading healthcare investment firm that has a proven track record of success and a deep understanding of the healthcare industry. Investors looking to gain exposure to the healthcare sector may want to consider Orbimed Advisors as a potential investment opportunity.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| BIOGEN INC | 42 | Q3 2023 | 5.0% |
| VERTEX PHARMACEUTICALS INC | 42 | Q3 2023 | 3.7% |
| THERMO FISHER SCIENTIFIC INC | 42 | Q3 2023 | 3.2% |
| SINOVAC BIOTECH LTD | 41 | Q3 2023 | 7.2% |
| NEUROCRINE BIOSCIENCES INC | 41 | Q3 2023 | 2.7% |
| BOSTON SCIENTIFIC CORP | 40 | Q3 2023 | 5.6% |
| BRISTOL-MYERS SQUIBB CO | 40 | Q2 2023 | 5.2% |
| AMGEN INC | 40 | Q3 2023 | 5.5% |
| INTUITIVE SURGICAL INC | 40 | Q3 2023 | 3.8% |
| GILEAD SCIENCES INC | 39 | Q3 2023 | 5.5% |
View Orbimed Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Ikena Oncology, Inc. | September 21, 2023 | 2,189,111 | 5.2% |
| Galecto, Inc. | September 18, 2023 | 749,557 | 2.8% |
| PMV Pharmaceuticals, Inc. | August 23, 2023 | 6,563,077 | 13.5% |
| Gracell Biotechnologies Inc. | August 11, 2023 | 7,641,531 | 8.0% |
| Xtant Medical Holdings, Inc. | August 03, 2023 | 73,114,592 | 56.7% |
| Turnstone Biologics Corp. | July 24, 2023 | 3,099,265 | 13.4% |
| Prelude Therapeutics Inc | May 24, 2023 | 15,716,642 | 28.6% |
| VectivBio Holding AG | May 24, 2023 | 5,156,561 | 7.7% |
| Fusion Pharmaceuticals Inc. | May 16, 2023 | 2,930,670 | 4.6% |
| Verona Pharma plc | May 16, 2023 | 3,777,778 | 4.8% |
View Orbimed Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 4 | 2024-05-08 |
| SC 13D/A | 2024-05-08 |
| 4 | 2024-05-03 |
| 4 | 2024-04-26 |
| 4 | 2024-04-23 |
| 4 | 2024-04-18 |
| 4 | 2024-04-15 |
| 3/A | 2024-04-12 |
| SC 13D/A | 2024-04-12 |
| 4 | 2024-04-05 |
View Orbimed Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.