| JOHNSON & JOHNSON | 6,641,064 | $32,607,624 | 12.01% |
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| Prosight Management, LP | 4,078,804 | $20,026,928 | 6.35% |
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| Perceptive Advisors | 11,331,103 | $55,635,715 | 1.86% |
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| 683 Capital Management, LLC | 2,457,609 | $12,066,861 | 0.94% |
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| Rhenman & Partners Asset Management AB | 538,986 | $2,646,421 | 0.28% |
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| Fort Sheridan Advisors LLC | 102,137 | $501,495 | 0.11% |
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| INNOVIS ASSET MANAGEMENT LLC | 30,496 | $149,736 | 0.06% |
|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4,671,017 | $22,934,693 | 0.05% |
|---|
| ROYCE & ASSOCIATES LP | 677,715 | $3,327,581 | 0.03% |
|---|
| CreativeOne Wealth, LLC | 81,009 | $398 | 0.03% |
|---|
| CORNERCAP INVESTMENT COUNSEL INC | 31,866 | $156,462 | 0.03% |
|---|
| Laurion Capital Management LP | 367,937 | $1,806,571 | 0.01% |
|---|
| Alyeska Investment Group, L.P. | 330,182 | $1,621,194 | 0.01% |
|---|
| TOCQUEVILLE ASSET MANAGEMENT L.P. | 20,150 | $98,937 | 0.00% |
|---|
| DAVENPORT & Co LLC | 64,355 | $315,983 | 0.00% |
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| BLAIR WILLIAM & CO/IL | 132,133 | $648,773 | 0.00% |
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| China Universal Asset Management Co., Ltd. | 1,522 | $7 | 0.00% |
|---|
| OneDigital Investment Advisors LLC | 15,970 | $78,413 | 0.00% |
|---|
| Russell Investments Group, Ltd. | 192,466 | $945,006 | 0.00% |
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| LETKO, BROSSEAU & ASSOCIATES INC | 22,700 | $111,457 | 0.00% |
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