| Sio Capital Management, LLC | 133,000 | $34,709 | 11.48% |
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| M.D. SASS INVESTORS SERVICES, INC. | 146,160 | $38,144 | 6.53% |
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| GREAT POINT PARTNERS LLC | 85,000 | $22,182 | 5.36% |
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| Eagle Health Investments LP | 82,144 | $21,437 | 5.28% |
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| Sio Capital Management, LLC | 58,500 | $15,267 | 5.05% |
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| MARVIN & PALMER ASSOCIATES INC | 42,546 | $11,103 | 5.00% |
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| Provident Investment Management, Inc. | 187,314 | $48,883 | 4.68% |
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| COLRAIN CAPITAL LLC | 10,000 | $2,610 | 3.64% |
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| BRIDGER MANAGEMENT, LLC | 82,800 | $21,608 | 3.54% |
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| DE BURLO GROUP INC | 68,410 | $17,852,958 | 3.32% |
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| Birch Hill Investment Advisors LLC | 234,102 | $61,094 | 3.26% |
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| Avidity Partners Management LP | 545,600 | $142,385 | 2.96% |
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| Shelter Mutual Insurance Co | 43,300 | $11,301 | 2.96% |
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| China Universal Asset Management Co., Ltd. | 32,039 | $8,361 | 2.96% |
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| Tekla Capital Management LLC | 308,884 | $80,609 | 2.83% |
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| SEAVIEW INVESTMENT MANAGERS LLC | 29,030 | $7,576 | 2.53% |
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| HARDING LOEVNER LP | 1,769,276 | $417,339 | 2.30% |
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| LOOMIS SAYLES & CO L P | 6,389,023 | $1,667,343 | 2.23% |
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| Van Hulzen Asset Management, LLC | 77,300 | $20,173 | 2.14% |
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| F/M Investments LLC | 10,076 | $2,629,534 | 2.12% |
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