| Flagship Pioneering Inc. | 4,632,149 | $550,067,694 | 65.22% |
|---|
| Theleme Partners LLP | 7,226,861 | $858,189,744 | 41.17% |
|---|
| Triatomic Management LP | 5,250 | $623,438 | 18.39% |
|---|
| WASHINGTON UNIVERSITY | 150,000 | $17,812,500 | 8.11% |
|---|
| Crawford Fund Management, LLC | 137,300 | $16,304,375 | 4.12% |
|---|
| Baillie Gifford | 43,449,041 | $5,159,573,619 | 4.02% |
|---|
| Lancaster Investment Management | 46,500 | $5,522 | 3.61% |
|---|
| Theleme Partners LLP | 6,204 | $73,691,112 | 3.54% |
|---|
| BANQUE PICTET & CIE SA | 3,154,429 | $374,588,444 | 3.39% |
|---|
| Intrinsic Value Partners, LLC | 26,887 | $3,192,831 | 3.33% |
|---|
| Bellevue Group AG | 1,563,735 | $185,693,531 | 3.02% |
|---|
| Geo Capital Gestora de Recursos Ltd | 25,348 | $3,010 | 3.00% |
|---|
| Mission Creek Capital Partners, Inc. | 92,017 | $10,927,019 | 2.75% |
|---|
| QUATTRO FINANCIAL ADVISORS LLC | 87,100 | $10,343,125 | 2.70% |
|---|
| Telemark Asset Management, LLC | 250,000 | $29,687,500 | 2.58% |
|---|
| 683 Capital Management, LLC | 242,000 | $28,737,500 | 2.17% |
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| TITLEIST ASSET MANAGEMENT, LLC | 103,444 | $12,284,000 | 1.85% |
|---|
| Provident Co of the Employees of the Hebrew University LTD | 12,965 | $1,539,184 | 1.83% |
|---|
| CADINHA & CO LLC | 82,193 | $9,760,419 | 1.81% |
|---|
| Bank Pictet & Cie (Europe) AG | 522,626 | $62,061,838 | 1.51% |
|---|