| Pivotal bioVenture Partners Investment Advisor LLC | 797,008 | $134,766,083 | 53.75% |
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| Nan Fung Group Holdings Ltd | 225,688 | $38,161,584 | 30.90% |
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| Sofinnova Investments, Inc. | 1,381,149 | $233,538,484 | 14.73% |
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| First Light Asset Management, LLC | 303,137 | $51,257,435 | 4.87% |
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| Altium Capital Management LP | 34,000 | $5,749,060 | 3.00% |
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| DAFNA Capital Management LLC | 52,873 | $8,940,296 | 2.78% |
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| Logos Global Management LP | 115,000 | $19,445,350 | 2.59% |
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| GENERAL ATLANTIC, L.P. | 986,710 | $166,842,794 | 2.58% |
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| MPM BioImpact LLC | 53,210 | $8,997,279 | 2.40% |
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| Rock Springs Capital Management LP | 505,433 | $85,463,666 | 2.29% |
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| Boxer Capital, LLC | 250,000 | $42,272,500 | 2.25% |
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| CATALYST PRIVATE WEALTH, LLC | 21,837 | $3,692,418 | 2.18% |
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| Avidity Partners Management LP | 286,700 | $48,478,103 | 1.95% |
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| GREAT POINT PARTNERS LLC | 60,500 | $10,229,945 | 1.86% |
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| Patient Capital Management, LLC | 176,252 | $29,802,411 | 1.75% |
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| INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 30,500 | $5,157,245 | 1.74% |
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| Clarius Group, LLC | 99,221 | $16,777,279 | 1.60% |
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| Parkman Healthcare Partners LLC | 51,311 | $8,676,177 | 1.59% |
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| Cormorant Asset Management, LP | 140,000 | $23,672,600 | 1.38% |
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| Sio Capital Management, LLC | 24,129 | $4,079,973 | 1.26% |
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