| Evolutionary Tree Capital Management, LLC | 16,669 | $3,307,796 | 4.27% |
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| Eagle Health Investments LP | 93,243 | $18,503,141 | 4.08% |
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| Atika Capital Management LLC | 140,165 | $27,814,343 | 3.65% |
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| Eversept Partners, LP | 193,018 | $38,302,492 | 3.24% |
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| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 368,526 | $73,130,299 | 3.19% |
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| Integral Health Asset Management, LLC | 105,000 | $20,836,200 | 2.88% |
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| Prosight Management, LP | 40,000 | $7,937,600 | 2.52% |
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| Velan Capital Investment Management LP | 15,300 | $3,036,132 | 2.45% |
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| Kopp Family Office, LLC | 18,112 | $3,594 | 2.28% |
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| Miura Global Management | 15,000 | $2,976,600 | 2.04% |
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| PURA VIDA INVESTMENTS, LLC | 40,487 | $8,034,240 | 1.52% |
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| AtonRa Partners | 3,423 | $679,260 | 1.42% |
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| GILDER GAGNON HOWE & CO LLC | 463,094 | $91,896,324 | 1.40% |
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| Bullseye Asset Management LLC | 12,387 | $2,459 | 1.37% |
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| Intrinsic Edge Capital Management LLC | 56,371 | $11,186,261 | 1.26% |
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| WASATCH ADVISORS LP | 977,607 | $193,996,333 | 1.23% |
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| NEXT CENTURY GROWTH INVESTORS LLC | 47,855 | $9,496,346 | 1.03% |
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| Paloma Partners Management Co | 150,000 | $29,766,000 | 1.03% |
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| WESTFIELD CAPITAL MANAGEMENT CO LP | 732,400 | $145,337,456 | 0.99% |
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| Parkman Healthcare Partners LLC | 26,923 | $5,342,600 | 0.98% |
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