| Date | Person | Title | Type | Name | Shares | Shares (Total) | Price | Code |
|---|---|---|---|---|---|---|---|---|
| 2024-03-28 | HARRIGAN EDMUND | Buy | Common Stock | 413.0 | 13,115 | $57.0 | A | |
| 2024-03-28 | Clancy Paul J | Buy | Common Stock | 403.0 | 15,785 | $57.0 | A | |
| 2024-03-28 | BAKER JULIANBAKER FELIXBaker Brothers Life Sciences LPBaker Bros. Advisors (GP) LLC667, L.P.BAKER BROS. ADVISORS LP | Buy | Common Stock | 543.0 | 33,447,981 | $0.0 | A | |
| 2024-03-28 | BAKER JULIANBAKER FELIXBaker Brothers Life Sciences LPBaker Bros. Advisors (GP) LLC667, L.P.BAKER BROS. ADVISORS LP | Buy | Common Stock | 543.0 | 2,970,073 | $0.0 | A | |
| 2024-03-25 | Trotta Matteo | Buy | Employee Stock Option (right to buy) | 21868.0 | 21,868 | $0.0 | A | |
| 2024-03-25 | Trotta Matteo | Buy | Common Stock | 7828.0 | 7,828 | $0.0 | A | |
| 2024-02-14 | SWAIN PAULA J | Buy | Common Stock | 7377.0 | 84,907 | $0.0 | A | |
| 2024-02-14 | Hoppenot Herve | Buy | Common Stock | 41577.0 | 502,333 | $0.0 | A | |
| 2024-02-14 | Stamoulis Christiana | Buy | Common Stock | 7377.0 | 89,983 | $0.0 | A | |
| 2024-02-14 | Flannelly Barry P | Buy | Common Stock | 7377.0 | 85,080 | $0.0 | A | |
| 2024-02-14 | Stein Steven H | Buy | Common Stock | 7377.0 | 97,595 | $0.0 | A | |
| 2024-02-14 | Iyengar Vijay K | Buy | Common Stock | 7377.0 | 50,789 | $0.0 | A | |
| 2024-02-12 | Stamoulis Christiana | Sell | Common Stock | -387.0 | 82,606 | $57.8 | F | |
| 2024-01-22 | Morrissey Michael James | Sell | Common Stock | -108.0 | 72,300 | $61.5 | F | |
| 2024-01-22 | Dickinson Jonathan Elliott | Sell | Common Stock | -108.0 | 44,380 | $61.5 | F | |
| 2024-01-19 | Morrissey Michael James | Sell | Common Stock | -122.0 | 72,408 | $61.5 | F | |
| 2024-01-19 | Dickinson Jonathan Elliott | Sell | Common Stock | -122.0 | 44,488 | $61.5 | F | |
| 2024-01-18 | Stamoulis Christiana | Buy | Employee Stock Option (right to buy) | 27668.0 | 27,668 | $0.0 | A | |
| 2024-01-18 | CAGNONI PABLO J | Buy | Employee Stock Option (right to buy) | 21843.0 | 21,843 | $0.0 | A | |
| 2024-01-18 | Morrissey Michael James | Buy | Common Stock | 11359.0 | 72,530 | $61.2 | A |